Entry |
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Symbol |
DHFR-TS
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Name |
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Pathway |
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Module |
M00126 | Tetrahydrofolate biosynthesis, GTP => THF |
M00841 | Tetrahydrofolate biosynthesis, mediated by PTPS, GTP => THF |
M00938 | Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP |
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Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09104 Nucleotide metabolism
00240 Pyrimidine metabolism
K13998 DHFR-TS; dihydrofolate reductase / thymidylate synthase
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
K13998 DHFR-TS; dihydrofolate reductase / thymidylate synthase
00670 One carbon pool by folate
K13998 DHFR-TS; dihydrofolate reductase / thymidylate synthase
Enzymes [BR:ko01000]
1. Oxidoreductases
1.5 Acting on the CH-NH group of donors
1.5.1 With NAD+ or NADP+ as acceptor
1.5.1.3 dihydrofolate reductase
K13998 DHFR-TS; dihydrofolate reductase / thymidylate synthase
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.45 thymidylate synthase
K13998 DHFR-TS; dihydrofolate reductase / thymidylate synthase
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Other DBs |
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Genes |
» show all
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Reference |
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Authors |
Lazar G, Zhang H, Goodman HM |
Title |
The origin of the bifunctional dihydrofolate reductase-thymidylate synthase isogenes of Arabidopsis thaliana. |
Journal |
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Sequence |
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Reference |
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Authors |
Schlichtherle IM, Roos DS, Van Houten JL |
Title |
Cloning and molecular analysis of the bifunctional dihydrofolate reductase-thymidylate synthase gene in the ciliated protozoan Paramecium tetraurelia. |
Journal |
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LinkDB |
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