KEGG   PATHWAY: aam00230
Entry
aam00230                    Pathway                                
Name
Purine metabolism - Apteryx mantelli mantelli (North Island brown kiwi)
Class
Metabolism; Nucleotide metabolism
Pathway map
aam00230  Purine metabolism
aam00230

Module
aam_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:aam00230]
aam_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:aam00230]
aam_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:aam00230]
aam_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:aam00230]
aam_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:aam00230]
aam_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:aam00230]
Other DBs
GO: 0006163 0042278
Organism
Apteryx mantelli mantelli (North Island brown kiwi) [GN:aam]
Gene
106496671  NUDT9; nudix hydrolase 9 [KO:K13988] [EC:3.6.1.13]
106496876  ADPRM; ADP-ribose/CDP-alcohol diphosphatase, manganese dependent [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
106485418  NUDT5; nudix hydrolase 5 [KO:K13987] [EC:3.6.1.13 3.6.1.58 2.7.7.96]
106487683  PGM1; phosphoglucomutase 1 [KO:K01835] [EC:5.4.2.2]
106490181  PGM2; phosphoglucomutase 2 [KO:K15779] [EC:5.4.2.2 5.4.2.7]
106485372  PRPS1; phosphoribosyl pyrophosphate synthetase 1 [KO:K00948] [EC:2.7.6.1]
106490080  PPAT; phosphoribosyl pyrophosphate amidotransferase [KO:K00764] [EC:2.4.2.14]
106494893  trifunctional purine biosynthetic protein adenosine-3-like [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
106494960  trifunctional purine biosynthetic protein adenosine-3 [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
106490207  PAICS; phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01587] [EC:4.1.1.21 6.3.2.6]
106488688  ADSL; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
106492325  ATIC; 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
106491411  APRT; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
106494681  NT5C2; 5'-nucleotidase, cytosolic II [KO:K01081] [EC:3.1.3.5]
106494751  cytosolic 5'-nucleotidase 1B-like [KO:K01081] [EC:3.1.3.5]
106487295  NT5M; 5',3'-nucleotidase, mitochondrial [KO:K01081] [EC:3.1.3.5]
106493289  NT5C1A; 5'-nucleotidase, cytosolic IA [KO:K01081] [EC:3.1.3.5]
106497037  cytosolic 5'-nucleotidase 1A-like [KO:K01081] [EC:3.1.3.5]
106485685  NT5C; 5', 3'-nucleotidase, cytosolic [KO:K01081] [EC:3.1.3.5]
106489586  NT5E; 5'-nucleotidase ecto [KO:K19970] [EC:3.1.3.5]
106489390  PNP; purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
106489185  LACC1; laccase domain containing 1 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
106484751  HPRT1; hypoxanthine phosphoribosyltransferase 1 [KO:K00760] [EC:2.4.2.8]
106483352  hypoxanthine-guanine phosphoribosyltransferase-like [KO:K00760] [EC:2.4.2.8]
106489413  IMPDH2; inosine monophosphate dehydrogenase 2 [KO:K00088] [EC:1.1.1.205]
106493141  NME2; NME/NM23 nucleoside diphosphate kinase 2 [KO:K00940] [EC:2.7.4.6]
106493142  nucleoside diphosphate kinase A [KO:K00940] [EC:2.7.4.6]
106499992  NME3; NME/NM23 nucleoside diphosphate kinase 3 [KO:K00940] [EC:2.7.4.6]
106500001  NME4; NME/NM23 nucleoside diphosphate kinase 4 [KO:K00940] [EC:2.7.4.6]
106490662  NME7; NME/NM23 family member 7 [KO:K00940] [EC:2.7.4.6]
106496137  NME6; NME/NM23 nucleoside diphosphate kinase 6 [KO:K00940] [EC:2.7.4.6]
106489620  AK9; adenylate kinase 9 [KO:K18533] [EC:2.7.4.3 2.7.4.6]
106494220  ectonucleoside triphosphate diphosphohydrolase 8-like [KO:K01510] [EC:3.6.1.5]
106494222  ENTPD8; ectonucleoside triphosphate diphosphohydrolase 8 [KO:K01510] [EC:3.6.1.5]
106494269  ectonucleoside triphosphate diphosphohydrolase 8-like [KO:K01510] [EC:3.6.1.5]
106494711  ENTPD1; ectonucleoside triphosphate diphosphohydrolase 1 [KO:K01510] [EC:3.6.1.5]
106491248  ENTPD3; ectonucleoside triphosphate diphosphohydrolase 3 [KO:K01510] [EC:3.6.1.5]
106487146  CANT1; calcium activated nucleotidase 1 [KO:K12304] [EC:3.6.1.6]
106485706  ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4 [KO:K12305] [EC:3.6.1.6]
106494176  ENTPD6; ectonucleoside triphosphate diphosphohydrolase 6 (putative) [KO:K01511] [EC:3.6.1.6]
106482860  ENTPD5; ectonucleoside triphosphate diphosphohydrolase 5 [KO:K01511] [EC:3.6.1.6]
106499238  ITPA; inosine triphosphatase [KO:K01519] [EC:3.6.1.66]
106482734  XDH; xanthine dehydrogenase [KO:K00106] [EC:1.17.1.4 1.17.3.2]
106493695  NUDT2; nudix hydrolase 2 [KO:K01518] [EC:3.6.1.17]
106497087  GMPS; guanine monophosphate synthase [KO:K01951] [EC:6.3.5.2]
106483469  GMPR; guanosine monophosphate reductase [KO:K00364] [EC:1.7.1.7]
106490941  GDA; guanine deaminase [KO:K01487] [EC:3.5.4.3]
106482084  GUK1; guanylate kinase 1 [KO:K00942] [EC:2.7.4.8]
106489774  RRM1; ribonucleotide reductase catalytic subunit M1 [KO:K10807] [EC:1.17.4.1]
106483902  RRM2B; ribonucleotide reductase regulatory TP53 inducible subunit M2B [KO:K10808] [EC:1.17.4.1]
106494774  RRM2; ribonucleotide reductase regulatory subunit M2 [KO:K10808] [EC:1.17.4.1]
106498010  HDDC2; HD domain containing 2 [KO:K07023] [EC:3.1.3.89]
106498862  DGUOK; deoxyguanosine kinase [KO:K00904] [EC:2.7.1.113]
106491894  DCK; deoxycytidine kinase [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
106493434  deoxycytidine kinase-like [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
106491441  HDDC3; HD domain containing 3 [KO:K21138] [EC:3.1.7.2]
106486222  PRUNE1; prune exopolyphosphatase [KO:K01514] [EC:3.6.1.11]
106492856  ADCY1; adenylate cyclase 1 [KO:K08041] [EC:4.6.1.1]
106492356  ADCY2; adenylate cyclase 2 [KO:K08042] [EC:4.6.1.1]
106499045  ADCY5; adenylate cyclase 5 [KO:K08045] [EC:4.6.1.1]
106483289  ADCY7; adenylate cyclase 7 [KO:K08047] [EC:4.6.1.1]
106496221  ADCY8; adenylate cyclase 8 [KO:K08048] [EC:4.6.1.1]
106482327  ADCY9; adenylate cyclase 9 [KO:K08049] [EC:4.6.1.1]
106493891  adenylate cyclase type 10-like [KO:K11265] [EC:4.6.1.1]
106492053  GUCY1A3; guanylate cyclase 1 soluble subunit alpha [KO:K12318] [EC:4.6.1.2]
106485845  guanylate cyclase soluble subunit beta-2-like [KO:K12319] [EC:4.6.1.2]
106492070  GUCY1B3; guanylate cyclase 1 soluble subunit beta [KO:K12319] [EC:4.6.1.2]
106485871  guanylate cyclase soluble subunit beta-2-like [KO:K12319] [EC:4.6.1.2]
106488668  GUCY2C; guanylate cyclase 2C [KO:K12320] [EC:4.6.1.2]
106487682  retinal guanylyl cyclase 1-like [KO:K12321] [EC:4.6.1.2]
106490807  GUCY2F; guanylate cyclase 2F, retinal [KO:K12322] [EC:4.6.1.2]
106493342  NPR2; natriuretic peptide receptor 2 [KO:K12324] [EC:4.6.1.2]
106489039  PDE1C; phosphodiesterase 1C [KO:K13755] [EC:3.1.4.17]
106498614  PDE1B; phosphodiesterase 1B [KO:K13755] [EC:3.1.4.17]
106499123  PDE1A; phosphodiesterase 1A [KO:K13755] [EC:3.1.4.17]
106486056  cGMP-dependent 3',5'-cyclic phosphodiesterase-like [KO:K18283] [EC:3.1.4.17]
106488616  cGMP-inhibited 3',5'-cyclic phosphodiesterase A-like [KO:K19021] [EC:3.1.4.17]
106497111  PDE3B; phosphodiesterase 3B [KO:K13296] [EC:3.1.4.17]
106491978  PDE5A; phosphodiesterase 5A [KO:K13762] [EC:3.1.4.35]
106482504  PDE6B; phosphodiesterase 6B [KO:K13756] [EC:3.1.4.35]
106484917  rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta-like [KO:K13756] [EC:3.1.4.35]
106491527  PDE6C; phosphodiesterase 6C [KO:K13757] [EC:3.1.4.35]
106483790  PDE6D; phosphodiesterase 6D [KO:K13758]
106488530  PDE6H; phosphodiesterase 6H [KO:K13760]
106483669  PDE9A; phosphodiesterase 9A [KO:K13761] [EC:3.1.4.35]
106486807  PDE10A; phosphodiesterase 10A [KO:K18438] [EC:3.1.4.17 3.1.4.35]
106499327  PDE11A; phosphodiesterase 11A [KO:K13298] [EC:3.1.4.17 3.1.4.35]
106485513  ADSS; adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
106491464  adenylosuccinate synthetase isozyme 2-like [KO:K01939] [EC:6.3.4.4]
106482996  ADSSL1; adenylosuccinate synthase like 1 [KO:K01939] [EC:6.3.4.4]
106485265  AMPD1; adenosine monophosphate deaminase 1 [KO:K01490] [EC:3.5.4.6]
106496940  AMPD2; adenosine monophosphate deaminase 2 [KO:K01490] [EC:3.5.4.6]
106497119  AMPD3; adenosine monophosphate deaminase 3 [KO:K01490] [EC:3.5.4.6]
106498933  ADK; adenosine kinase [KO:K00856] [EC:2.7.1.20]
106500118  ADA; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
106488944  CECR1; cat eye syndrome chromosome region, candidate 1 [KO:K19572] [EC:3.5.4.4]
106483081  AK7; adenylate kinase 7 [KO:K00939] [EC:2.7.4.3]
106495285  AK1; adenylate kinase 1 [KO:K00939] [EC:2.7.4.3]
106487282  AK4; adenylate kinase 4 [KO:K00939] [EC:2.7.4.3]
106483748  AK8; adenylate kinase 8 [KO:K00939] [EC:2.7.4.3]
106499465  AK5; adenylate kinase 5 [KO:K00939] [EC:2.7.4.3]
106493299  AK2; adenylate kinase 2 [KO:K00939] [EC:2.7.4.3]
106495175  AK6; adenylate kinase 6 [KO:K18532] [EC:2.7.4.3]
106496772  AK3; adenylate kinase 3 [KO:K00944] [EC:2.7.4.10]
106494259  ENTPD2; ectonucleoside triphosphate diphosphohydrolase 2 [KO:K01509] [EC:3.6.1.-]
106487311  NTPCR; nucleoside-triphosphatase, cancer-related [KO:K06928] [EC:3.6.1.15]
106497910  ENPP3; ectonucleotide pyrophosphatase/phosphodiesterase 3 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
106498023  ENPP1; ectonucleotide pyrophosphatase/phosphodiesterase 1 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
106485709  cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like [KO:K13293] [EC:3.1.4.53]
106484688  PDE4B; phosphodiesterase 4B [KO:K13293] [EC:3.1.4.53]
106495587  PDE4C; phosphodiesterase 4C [KO:K13293] [EC:3.1.4.53]
106495240  cAMP-specific 3',5'-cyclic phosphodiesterase 4D [KO:K13293] [EC:3.1.4.53]
106497915  PDE7B; phosphodiesterase 7B [KO:K18436] [EC:3.1.4.53]
106494369  PDE7A; phosphodiesterase 7A [KO:K18436] [EC:3.1.4.53]
106496529  PDE8A; phosphodiesterase 8A [KO:K18437] [EC:3.1.4.53]
106489564  FHIT; fragile histidine triad [KO:K01522] [EC:3.6.1.29]
106495208  ENPP4; ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) [KO:K18424] [EC:3.6.1.29]
106491990  PAPSS1; 3'-phosphoadenosine 5'-phosphosulfate synthase 1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
106489044  PAPSS2; 3'-phosphoadenosine 5'-phosphosulfate synthase 2 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
106499688  uricase-like [KO:K00365] [EC:1.7.3.3]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
aam00030  Pentose phosphate pathway
aam00220  Arginine biosynthesis
aam00250  Alanine, aspartate and glutamate metabolism
aam00260  Glycine, serine and threonine metabolism
aam00340  Histidine metabolism
aam00630  Glyoxylate and dicarboxylate metabolism
aam00730  Thiamine metabolism
aam00740  Riboflavin metabolism
aam00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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