KEGG   PATHWAY: aam04820
Entry
aam04820                    Pathway                                
Name
Cytoskeleton in muscle cells - Apteryx mantelli mantelli (North Island brown kiwi)
Class
Cellular Processes; Cell motility
Pathway map
aam04820  Cytoskeleton in muscle cells
aam04820

Organism
Apteryx mantelli mantelli (North Island brown kiwi) [GN:aam]
Gene
106487646  collagen alpha-1(I) chain [KO:K06236]
106483393  COL1A2; collagen type I alpha 2 chain [KO:K06236]
106499174  COL3A1; collagen type III alpha 1 chain [KO:K19720]
106500185  COL5A3; collagen type V alpha 3 chain [KO:K19721]
106499815  COL24A1; collagen type XXIV alpha 1 chain [KO:K19721]
106495542  COL27A1; collagen type XXVII alpha 1 chain [KO:K19721]
106499182  COL5A2; collagen type V alpha 2 chain [KO:K19721]
106495471  collagen alpha-1(V) chain [KO:K19721]
106499741  COL11A1; collagen type XI alpha 1 chain [KO:K19721]
106491577  collagen alpha-1(I) chain-like [KO:K19721]
106496618  collagen alpha-2(IX) chain-like [KO:K08131]
106492535  COL9A1; collagen type IX alpha 1 chain [KO:K08131]
106493499  COL9A3; collagen type IX alpha 3 chain [KO:K08131]
106488654  DCN; decorin [KO:K04660]
106484676  ELN; elastin [KO:K14211]
106491159  collagen alpha-4(VI) chain-like [KO:K06238]
106484387  COL6A3; collagen type VI alpha 3 chain [KO:K06238]
106482282  COL6A1; collagen type VI alpha 1 chain [KO:K06238]
106482286  COL6A2; collagen type VI alpha 2 chain [KO:K06238]
106482797  THBS1; thrombospondin 1 [KO:K16857]
106494326  THBS3; thrombospondin 3 [KO:K04659]
106496803  COMP; cartilage oligomeric matrix protein [KO:K04659]
106487359  THBS2; thrombospondin 2 [KO:K04659]
106496465  FBN1; fibrillin 1 [KO:K06825]
106497721  fibrillin-2-like [KO:K23342]
106485911  COL4A4; collagen type IV alpha 4 chain [KO:K06237]
106482661  COL4A5; collagen type IV alpha 5 chain [KO:K06237]
106482670  collagen alpha-6(IV) chain-like [KO:K06237]
106485842  COL4A3; collagen type IV alpha 3 chain [KO:K06237]
106493997  COL4A1; collagen type IV alpha 1 chain [KO:K06237]
106493998  COL4A2; collagen type IV alpha 2 chain [KO:K06237]
106488554  FBLN1; fibulin 1 [KO:K17307]
106488746  FBLN2; fibulin 2 [KO:K17307]
106485404  NID1; nidogen 1 [KO:K06826]
106487690  SDC1; syndecan 1 [KO:K06257]
106483861  SDC2; syndecan 2 [KO:K16336]
106489426  SDC3; syndecan 3 [KO:K16337]
106493375  SDC4; syndecan 4 [KO:K16338]
106495570  AGRN; agrin [KO:K06254]
106484567  desmocollin-1-like [KO:K07601]
106484568  DSG2; desmoglein 2 [KO:K07597]
106488825  PKP2; plakophilin 2 [KO:K12642]
106487633  JUP; junction plakoglobin [KO:K10056]
106483753  DSP; desmoplakin [KO:K10381]
106489924  vimentin [KO:K07606]
106499086  DES; desmin [KO:K07610]
106497996  LAMA2; laminin subunit alpha 2 [KO:K05637]
106484524  LAMA1; laminin subunit alpha 1 [KO:K05637]
106489819  integrin alpha-2-like [KO:K06481]
106499982  ITGA2; integrin subunit alpha 2 [KO:K06481]
106492755  ITGA3; integrin subunit alpha 3 [KO:K06482]
106499121  ITGA4; integrin subunit alpha 4 [KO:K06483]
106499243  ITGA6; integrin subunit alpha 6 [KO:K06485]
106483498  ITGA8; integrin subunit alpha 8 [KO:K06584]
106489001  ITGA9; integrin subunit alpha 9 [KO:K06585]
106492271  ITGA11; integrin subunit alpha 11 [KO:K06587]
106499128  ITGAV; integrin subunit alpha V [KO:K06487]
106489947  ITGB1; integrin subunit beta 1 [KO:K05719]
106485578  integrin beta-3-like [KO:K06493]
106485378  integrin beta-3-like [KO:K06493]
106485674  ITGB4; integrin subunit beta 4 [KO:K06525]
106499039  integrin beta-5-like [KO:K06588]
106499040  integrin beta-5-like [KO:K06588]
106499136  ITGB6; integrin subunit beta 6 [KO:K06589]
106483431  ITGB8; integrin subunit beta 8 [KO:K06591]
106499531  TLN1; talin 1 [KO:K06271]
106496464  TLN2; talin 2 [KO:K06271]
106498898  VCL; vinculin [KO:K05700]
106491462  alpha-actinin-3-like [KO:K21073]
106485448  ACTN2; actinin alpha 2 [KO:K21073]
106491504  ACTG1; actin gamma 1 [KO:K05692]
106497766  actin, cytoplasmic type 5 [KO:K05692]
106497948  actin, cytoplasmic 1 [KO:K05692]
106492183  DAG1; dystroglycan 1 [KO:K06265]
106483397  SGCE; sarcoglycan epsilon [KO:K27061]
106490183  SGCB; sarcoglycan beta [KO:K12566]
106493635  SGCD; sarcoglycan delta [KO:K12563]
106500409  SGCG; sarcoglycan gamma [KO:K12564]
106490117  SGCZ; sarcoglycan zeta [KO:K27062]
106488302  SSPN; sarcospan [KO:K22194]
106496316  SNTB1; syntrophin beta 1 [KO:K24064]
106494459  DTNA; dystrobrevin alpha [KO:K26998]
106498419  filamin-C-like [KO:K27393]
106500059  ATP1A2; ATPase Na+/K+ transporting subunit alpha 2 [KO:K01539] [EC:7.2.2.13]
106490649  ATP1A1; ATPase Na+/K+ transporting subunit alpha 1 [KO:K01539] [EC:7.2.2.13]
106487548  ATP1B4; ATPase Na+/K+ transporting family member beta 4 [KO:K01540]
106485899  ATP1B3; ATPase Na+/K+ transporting subunit beta 3 [KO:K01540]
106490663  ATP1B1; ATPase Na+/K+ transporting subunit beta 1 [KO:K01540]
106495458  ANK3; ankyrin 3 [KO:K09259]
106495383  SPTAN1; spectrin alpha, non-erythrocytic 1 [KO:K06114]
106498270  SPTBN5; spectrin beta, non-erythrocytic 5 [KO:K06115]
106493724  SPTBN4; spectrin beta, non-erythrocytic 4 [KO:K06115]
106490379  SPTBN1; spectrin beta, non-erythrocytic 1 [KO:K06115]
106499631  cysteine and glycine-rich protein 1 [KO:K09377]
106488810  cysteine and glycine-rich protein 2 [KO:K09377]
106488166  cysteine and glycine-rich protein 2-like [KO:K09377]
106498233  CSRP3; cysteine and glycine rich protein 3 [KO:K09377]
106500242  CSRP1; cysteine and glycine rich protein 1 [KO:K09377]
106496872  myosin heavy chain, skeletal muscle, adult-like [KO:K24220]
106496871  myosin heavy chain, skeletal muscle, adult [KO:K24220]
106490133  MYH7B; myosin heavy chain 7B [KO:K24220]
106490592  MYH15; myosin heavy chain 15 [KO:K24220]
106496862  myosin heavy chain, skeletal muscle, adult-like [KO:K24220]
106484950  myosin-6-like [KO:K17751]
106482581  MYH11; myosin heavy chain 11 [KO:K10352]
106488543  MYH9; myosin heavy chain 9 [KO:K10352]
106493188  MYH10; myosin heavy chain 10 [KO:K10352]
106492363  MYL1; myosin light chain 1 [KO:K05738]
106485299  MYL3; myosin light chain 3 [KO:K12749]
106497421  MYL4; myosin light chain 4 [KO:K12750]
106495672  MYL2; myosin light chain 2 [KO:K10351]
106482513  MYL5; myosin light chain 5 [KO:K12753]
106483926  myosin regulatory light chain 2, atrial isoform-like [KO:K12754]
106499912  MYL9; myosin light chain 9 [KO:K12755]
106488265  MYBPC1; myosin binding protein C, slow type [KO:K12557]
106498120  MYBPC3; myosin binding protein C, cardiac [KO:K12568]
106485630  MYBPH; myosin binding protein H [KO:K24494]
106487350  ACTA1; actin, alpha 1, skeletal muscle [KO:K10354]
106482816  ACTC1; actin, alpha, cardiac muscle 1 [KO:K12314]
106498226  actin, alpha skeletal muscle B-like [KO:K12314]
106487044  TNNC1; troponin C1, slow skeletal and cardiac type [KO:K05865]
106485638  TNNI1; troponin I1, slow skeletal type [KO:K10371]
106497601  TNNC2; troponin C2, fast skeletal type [KO:K12042]
106497045  TNNI2; troponin I2, fast skeletal type [KO:K12043]
106496993  TNNT3; troponin T3, fast skeletal type [KO:K12046]
106485633  troponin T, cardiac muscle isoforms-like [KO:K12045]
106485634  troponin T, cardiac muscle isoforms [KO:K12045]
106496455  TPM1; tropomyosin 1 (alpha) [KO:K10373]
106499505  TPM2; tropomyosin 2 (beta) [KO:K10374]
106484291  TPM3; tropomyosin 3 [KO:K09290]
106494274  TPM4; tropomyosin 4 [KO:K10375]
106499120  TTN; titin [KO:K12567] [EC:2.7.11.1]
106487194  MYOT; myotilin [KO:K19875]
106491983  SYNPO2; synaptopodin 2 [KO:K24066]
106482302  NEB; nebulin [KO:K18267]
106489955  NEBL; nebulette [KO:K25865]
106498906  MYOZ1; myozenin 1 [KO:K26050]
106491902  MYOZ2; myozenin 2 [KO:K26050]
106493570  MYOZ3; myozenin 3 [KO:K26050]
106484037  PDLIM3; PDZ and LIM domain 3 [KO:K23353]
106487238  PDLIM4; PDZ and LIM domain 4 [KO:K23353]
106498875  PDZ and LIM domain protein 1-like [KO:K23353]
106485259  CAPZA1; capping actin protein of muscle Z-line alpha subunit 1 [KO:K10364]
106488128  CAPZA2; capping actin protein of muscle Z-line alpha subunit 2 [KO:K10364]
106488291  CAPZA3; capping actin protein of muscle Z-line alpha subunit 3 [KO:K10364]
106487389  CAPZB; capping actin protein of muscle Z-line beta subunit [KO:K10365]
106490280  XIRP1; xin actin binding repeat containing 1 [KO:K27381]
106499103  XIRP2; xin actin binding repeat containing 2 [KO:K27381]
106483725  NRAP; nebulin related anchoring protein [KO:K24421]
106486947  MYPN; myopalladin [KO:K22028]
106499864  LDB3; LIM domain binding 3 [KO:K19867]
106492075  PDZ and LIM domain protein 5-like [KO:K19867]
106489868  PDLIM7; PDZ and LIM domain 7 [KO:K19867]
106492074  PDZ and LIM domain protein 5-like [KO:K19867]
106486926  TMOD1; tropomodulin 1 [KO:K10370]
106496488  TMOD3; tropomodulin 3 [KO:K10370]
106484819  TMOD4; tropomodulin 4 [KO:K10370]
106496558  tropomodulin-2 [KO:K10370]
106497257  ZYX; zyxin [KO:K06273]
106484774  FHL1; four and a half LIM domains 1 [KO:K14365]
106493977  FHL2; four and a half LIM domains 2 [KO:K14380]
106490900  FHL3; four and a half LIM domains 3 [KO:K24414]
106495908  LMOD2; leiomodin 2 [KO:K22030]
106491479  leiomodin-1-like [KO:K22030]
106485625  LMOD1; leiomodin 1 [KO:K22030]
106494567  LMOD3; leiomodin 3 [KO:K22030]
106498963  ankyrin repeat domain-containing protein 1-like [KO:K21433]
106494111  ANKRD1; ankyrin repeat domain 1 [KO:K21433]
106493658  FMNL2; formin like 2 [KO:K23957]
106495645  FMNL1; formin like 1 [KO:K23957]
106483096  inverted formin-2-like [KO:K23958]
106483095  inverted formin-2-like [KO:K23958]
106485529  DAAM2; dishevelled associated activator of morphogenesis 2 [KO:K04512]
106495229  DAAM1; dishevelled associated activator of morphogenesis 1 [KO:K04512]
106488058  DIAPH1; diaphanous related formin 1 [KO:K05740]
106496814  DIAPH2; diaphanous related formin 2 [KO:K05741]
106491678  DIAPH3; diaphanous related formin 3 [KO:K05745]
106485472  FMN2; formin 2 [KO:K02184]
106484624  MYOM1; myomesin 1 [KO:K24495]
106486678  MYOM2; myomesin 2 [KO:K24495]
106493294  MYOM3; myomesin 3 [KO:K24495]
106497211  ENO2; enolase 2 [KO:K01689] [EC:4.2.1.11]
106482746  ENO1; enolase 1 [KO:K01689] [EC:4.2.1.11]
106491999  ANK2; ankyrin 2 [KO:K09255]
106492210  CKM; creatine kinase, M-type [KO:K27382] [EC:2.7.3.2]
106497701  TRIM54; tripartite motif containing 54 [KO:K10653]
106488712  E3 ubiquitin-protein ligase Midline-1-like [KO:K10653]
106484594  TRIM55; tripartite motif containing 55 [KO:K10654]
106488915  TRIM63; tripartite motif containing 63 [KO:K10655] [EC:2.3.2.27]
106485265  AMPD1; adenosine monophosphate deaminase 1 [KO:K01490] [EC:3.5.4.6]
106496940  AMPD2; adenosine monophosphate deaminase 2 [KO:K01490] [EC:3.5.4.6]
106497119  AMPD3; adenosine monophosphate deaminase 3 [KO:K01490] [EC:3.5.4.6]
106492940  PLEC; plectin [KO:K10388]
106482946  SYNE3; spectrin repeat containing nuclear envelope family member 3 [KO:K21761]
106496893  SYNE1; spectrin repeat containing nuclear envelope protein 1 [KO:K19326]
106483100  SYNE2; spectrin repeat containing nuclear envelope protein 2 [KO:K19346]
106491357  SUN1; Sad1 and UNC84 domain containing 1 [KO:K19347]
106488960  SUN2; Sad1 and UNC84 domain containing 2 [KO:K19347]
106499004  TMEM43; transmembrane protein 43 [KO:K27488]
106482709  LBR; lamin B receptor [KO:K19532] [EC:1.3.1.70]
106492305  LMNA; lamin A/C [KO:K12641]
106496418  lamin-L(III)-like [KO:K07611]
106497709  LMNB2; lamin B2 [KO:K07611]
Reference
PMID:12142273
  Authors
Clark KA, McElhinny AS, Beckerle MC, Gregorio CC
  Title
Striated muscle cytoarchitecture: an intricate web of form and function.
  Journal
Annu Rev Cell Dev Biol 18:637-706 (2002)
DOI:10.1146/annurev.cellbio.18.012502.105840
Reference
PMID:31407867
  Authors
Mukund K, Subramaniam S
  Title
Skeletal muscle: A review of molecular structure and function, in health and disease.
  Journal
Wiley Interdiscip Rev Syst Biol Med 12:e1462 (2020)
DOI:10.1002/wsbm.1462
Reference
PMID:24481844
  Authors
Stroud MJ, Banerjee I, Veevers J, Chen J
  Title
Linker of nucleoskeleton and cytoskeleton complex proteins in cardiac structure, function, and disease.
  Journal
Circ Res 114:538-48 (2014)
DOI:10.1161/CIRCRESAHA.114.301236
Reference
PMID:28640448
  Authors
Henderson CA, Gomez CG, Novak SM, Mi-Mi L, Gregorio CC
  Title
Overview of the Muscle Cytoskeleton.
  Journal
Compr Physiol 7:891-944 (2017)
DOI:10.1002/cphy.c160033
Reference
PMID:32265741
  Authors
Csapo R, Gumpenberger M, Wessner B
  Title
Skeletal Muscle Extracellular Matrix - What Do We Know About Its Composition, Regulation, and Physiological Roles? A Narrative Review.
  Journal
Front Physiol 11:253 (2020)
DOI:10.3389/fphys.2020.00253
Reference
PMID:27114860
  Authors
Pinch M, Guth R, Samanta MP, Chaidez A, Unguez GA
  Title
The myogenic electric organ of Sternopygus macrurus: a non-contractile tissue with a skeletal muscle transcriptome.
  Journal
PeerJ 4:e1828 (2016)
DOI:10.7717/peerj.1828
Reference
PMID:23860255
  Authors
Sequeira V, Nijenkamp LL, Regan JA, van der Velden J
  Title
The physiological role of cardiac cytoskeleton and its alterations in heart failure.
  Journal
Biochim Biophys Acta 1838:700-22 (2014)
DOI:10.1016/j.bbamem.2013.07.011
Reference
PMID:36960155
  Authors
Zhang B, Powers JD, McCulloch AD, Chi NC
  Title
Nuclear mechanosignaling in striated muscle diseases.
  Journal
Front Physiol 14:1126111 (2023)
DOI:10.3389/fphys.2023.1126111
Reference
PMID:21464301
  Authors
Al-Amoudi A, Castano-Diez D, Devos DP, Russell RB, Johnson GT, Frangakis AS
  Title
The three-dimensional molecular structure of the desmosomal plaque.
  Journal
Proc Natl Acad Sci U S A 108:6480-5 (2011)
DOI:10.1073/pnas.1019469108
Reference
PMID:33067392
  Authors
Sikora M, Ermel UH, Seybold A, Kunz M, Calloni G, Reitz J, Vabulas RM, Hummer G, Frangakis AS
  Title
Desmosome architecture derived from molecular dynamics simulations and cryo-electron tomography.
  Journal
Proc Natl Acad Sci U S A 117:27132-27140 (2020)
DOI:10.1073/pnas.2004563117
Reference
PMID:26910421
  Authors
Xu XP, Kim E, Swift M, Smith JW, Volkmann N, Hanein D
  Title
Three-Dimensional Structures of Full-Length, Membrane-Embedded Human alpha(IIb)beta(3) Integrin Complexes.
  Journal
Biophys J 110:798-809 (2016)
DOI:10.1016/j.bpj.2016.01.016
Reference
PMID:22945352
  Authors
Wang W, Shi Z, Jiao S, Chen C, Wang H, Liu G, Wang Q, Zhao Y, Greene MI, Zhou Z
  Title
Structural insights into SUN-KASH complexes across the nuclear envelope.
  Journal
Cell Res 22:1440-52 (2012)
DOI:10.1038/cr.2012.126
Reference
PMID:23597672
  Authors
Sosa BA, Kutay U, Schwartz TU
  Title
Structural insights into LINC complexes.
  Journal
Curr Opin Struct Biol 23:285-91 (2013)
DOI:10.1016/j.sbi.2013.03.005
Reference
PMID:33058875
  Authors
Cruz VE, Esra Demircioglu F, Schwartz TU
  Title
Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes.
  Journal
J Mol Biol 432:6028-6041 (2020)
DOI:10.1016/j.jmb.2020.09.019
Reference
PMID:36523505
  Authors
Schuler SC, Liu Y, Dumontier S, Grandbois M, Le Moal E, Cornelison D, Bentzinger CF
  Title
Extracellular matrix: Brick and mortar in the skeletal muscle stem cell niche.
  Journal
Front Cell Dev Biol 10:1056523 (2022)
DOI:10.3389/fcell.2022.1056523
Reference
PMID:30425656
  Authors
Brull A, Morales Rodriguez B, Bonne G, Muchir A, Bertrand AT
  Title
The Pathogenesis and Therapies of Striated Muscle Laminopathies.
  Journal
Front Physiol 9:1533 (2018)
DOI:10.3389/fphys.2018.01533
Reference
PMID:36552829
  Authors
Storey EC, Fuller HR
  Title
Genotype-Phenotype Correlations in Human Diseases Caused by Mutations of LINC Complex-Associated Genes: A Systematic Review and Meta-Summary.
  Journal
Cells 11:cells11244065 (2022)
DOI:10.3390/cells11244065
Related
pathway
aam04512  ECM-receptor interaction
aam04814  Motor proteins
KO pathway
ko04820   
LinkDB

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