KEGG   PATHWAY: masi00310
Entry
masi00310                   Pathway                                
Name
Lysine degradation - Myxocyprinus asiaticus (Chinese sucker)
Class
Metabolism; Amino acid metabolism
Pathway map
masi00310  Lysine degradation
masi00310

Module
masi_M00032  Lysine degradation, lysine => saccharopine => acetoacetyl-CoA [PATH:masi00310]
Other DBs
GO: 0006554
Organism
Myxocyprinus asiaticus (Chinese sucker) [GN:masi]
Gene
127435942  alpha-aminoadipic semialdehyde synthase, mitochondrial isoform X1 [KO:K14157] [EC:1.5.1.8 1.5.1.9]
127432454  alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
127453048  kynurenine/alpha-aminoadipate aminotransferase, mitochondrial [KO:K00825] [EC:2.6.1.7 2.6.1.39]
127436111  2-oxoadipate dehydrogenase complex component E1 [KO:K15791] [EC:1.2.4.-]
127455380  dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial-like isoform X1 [KO:K00658] [EC:2.3.1.61]
127410965  dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial-like isoform X1 [KO:K00658] [EC:2.3.1.61]
127437741  dihydrolipoyl dehydrogenase, mitochondrial-like [KO:K00382] [EC:1.8.1.4]
127436342  dihydrolipoyl dehydrogenase, mitochondrial-like [KO:K00382] [EC:1.8.1.4]
127450250  glutaryl-CoA dehydrogenase, mitochondrial-like [KO:K00252] [EC:1.3.8.6]
127446642  glutaryl-CoA dehydrogenase a [KO:K00252] [EC:1.3.8.6]
127416366  hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha a isoform X1 [KO:K07515] [EC:4.2.1.17 1.1.1.211]
127455035  trifunctional enzyme subunit alpha, mitochondrial-like [KO:K07515] [EC:4.2.1.17 1.1.1.211]
127447182  peroxisomal bifunctional enzyme isoform X1 [KO:K07514] [EC:4.2.1.17 1.1.1.35 5.3.3.8]
127412081  enoyl-CoA hydratase, mitochondrial [KO:K07511] [EC:4.2.1.17]
127414186  enoyl-CoA hydratase, mitochondrial-like isoform X1 [KO:K07511] [EC:4.2.1.17]
127444097  hydroxyacyl-coenzyme A dehydrogenase, mitochondrial [KO:K00022] [EC:1.1.1.35]
127432429  acetyl-CoA acetyltransferase, mitochondrial [KO:K00626] [EC:2.3.1.9]
127433513  acetyl-CoA acetyltransferase, mitochondrial-like isoform X1 [KO:K00626] [EC:2.3.1.9]
127415633  acetyl-CoA acetyltransferase, cytosolic [KO:K00626] [EC:2.3.1.9]
127438149  hydroxylysine kinase-like isoform X1 [KO:K18201] [EC:2.7.1.81]
127438719  hydroxylysine kinase-like [KO:K18201] [EC:2.7.1.81]
127430088  5-phosphohydroxy-L-lysine phospho-lyase-like isoform X1 [KO:K18202] [EC:4.2.3.134]
127422420  peroxisomal sarcosine oxidase [KO:K00306] [EC:1.5.3.1 1.5.3.7]
127412244  calmodulin-lysine N-methyltransferase-like isoform X1 [KO:K18826] [EC:2.1.1.60]
127421727  histone-lysine N-methyltransferase 2A-like [KO:K09186] [EC:2.1.1.354]
127429777  histone-lysine N-methyltransferase 2A-like isoform X1 [KO:K09186] [EC:2.1.1.354]
127418716  histone-lysine N-methyltransferase 2D-like isoform X1 [KO:K09187] [EC:2.1.1.354]
127419740  histone-lysine N-methyltransferase 2D-like isoform X1 [KO:K09187] [EC:2.1.1.354]
127431841  histone-lysine N-methyltransferase 2C-like isoform X1 [KO:K09188] [EC:2.1.1.354]
127434229  histone-lysine N-methyltransferase 2C-like isoform X1 [KO:K09188] [EC:2.1.1.354]
127441623  histone-lysine N-methyltransferase 2C-like isoform X1 [KO:K09188] [EC:2.1.1.354]
127442645  histone-lysine N-methyltransferase 2C isoform X1 [KO:K09188] [EC:2.1.1.354]
127425593  histone-lysine N-methyltransferase 2B-like isoform X1 [KO:K14959] [EC:2.1.1.354]
127421184  histone-lysine N-methyltransferase 2B-like isoform X1 [KO:K14959] [EC:2.1.1.354]
127422178  histone-lysine N-methyltransferase 2B-like [KO:K14959] [EC:2.1.1.354]
127429839  histone-lysine N-methyltransferase 2B-like [KO:K14959] [EC:2.1.1.354]
127436493  inactive histone-lysine N-methyltransferase 2E-like isoform X1 [KO:K09189] [EC:2.1.1.354]
127435394  inactive histone-lysine N-methyltransferase 2E-like isoform X1 [KO:K09189] [EC:2.1.1.354]
127450448  histone-lysine N-methyltransferase SETD1A isoform X1 [KO:K11422] [EC:2.1.1.354]
127432980  histone-lysine N-methyltransferase SETD1B-A isoform X1 [KO:K11422] [EC:2.1.1.354]
127433402  histone-lysine N-methyltransferase SETD1B-A-like isoform X1 [KO:K11422] [EC:2.1.1.354]
127452313  LOW QUALITY PROTEIN: histone-lysine N-methyltransferase SETD1A-like [KO:K11422] [EC:2.1.1.354]
127415408  histone-lysine N-methyltransferase SETD1B [KO:K11422] [EC:2.1.1.354]
127413043  histone-lysine N-methyltransferase SETD7 isoform X1 [KO:K11431] [EC:2.1.1.364]
127417647  histone-lysine N-methyltransferase SETD7-like isoform X1 [KO:K11431] [EC:2.1.1.364]
127422907  histone-lysine N-methyltransferase PRDM9 isoform X1 [KO:K20796] [EC:2.1.1.354]
127425594  histone-lysine N-methyltransferase ASH1L [KO:K06101] [EC:2.1.1.354]
127420966  histone-lysine N-methyltransferase ASH1L-like [KO:K06101] [EC:2.1.1.354]
127455610  N-lysine methyltransferase SMYD2-A-like [KO:K11426] [EC:2.1.1.354 2.1.1.357]
127455620  histone-lysine N-methyltransferase SMYD3-like [KO:K11426] [EC:2.1.1.354 2.1.1.357]
127414566  histone-lysine N-methyltransferase SMYD1b isoform X1 [KO:K11426] [EC:2.1.1.354 2.1.1.357]
127415843  N-lysine methyltransferase SMYD2-B [KO:K11426] [EC:2.1.1.354 2.1.1.357]
127422792  histone-lysine N-methyltransferase SMYD1-like [KO:K11426] [EC:2.1.1.354 2.1.1.357]
127410894  N-lysine methyltransferase SMYD2-A [KO:K11426] [EC:2.1.1.354 2.1.1.357]
127411468  histone-lysine N-methyltransferase SMYD3 isoform X1 [KO:K11426] [EC:2.1.1.354 2.1.1.357]
127424355  histone-lysine N-methyltransferase SUV39H1-A [KO:K11419] [EC:2.1.1.355]
127414501  histone-lysine N-methyltransferase SUV39H1b [KO:K11419] [EC:2.1.1.355]
127423831  histone-lysine N-methyltransferase SUV39H1-like [KO:K11419] [EC:2.1.1.355]
127430577  histone-lysine N-methyltransferase EHMT1-like isoform X1 [KO:K11420] [EC:2.1.1.355]
127425224  histone-lysine N-methyltransferase EHMT2-like [KO:K11420] [EC:2.1.1.355]
127439577  histone-lysine N-methyltransferase EHMT1a isoform X1 [KO:K11420] [EC:2.1.1.355]
127421499  histone-lysine N-methyltransferase EHMT2-like isoform X1 [KO:K11420] [EC:2.1.1.355]
127428598  histone-lysine N-methyltransferase EHMT1 isoform X1 [KO:K11420] [EC:2.1.1.355]
127425596  histone-lysine N-methyltransferase SETDB1-A-like isoform X1 [KO:K11421] [EC:2.1.1.366]
127420967  histone-lysine N-methyltransferase SETDB1-A-like [KO:K11421] [EC:2.1.1.366]
127452895  histone-lysine N-methyltransferase SETDB1-B-like isoform X1 [KO:K11421] [EC:2.1.1.366]
127453831  histone-lysine N-methyltransferase SETDB1-B [KO:K11421] [EC:2.1.1.366]
127443437  histone-lysine N-methyltransferase SETDB2 isoform X1 [KO:K18494] [EC:2.1.1.355]
127424417  PR domain zinc finger protein 2-like isoform X1 [KO:K11432] [EC:2.1.1.355]
127425848  PR domain zinc finger protein 2-like [KO:K11432] [EC:2.1.1.355]
127414460  PR domain zinc finger protein 2 [KO:K11432] [EC:2.1.1.355]
127427622  PR domain zinc finger protein 2-like [KO:K11432] [EC:2.1.1.355]
127449771  histone-lysine N-methyltransferase EZH1-like isoform X1 [KO:K17451] [EC:2.1.1.356]
127451124  histone-lysine N-methyltransferase EZH1-like isoform X1 [KO:K17451] [EC:2.1.1.356]
127431759  histone-lysine N-methyltransferase EZH2-like [KO:K11430] [EC:2.1.1.356]
127434185  histone-lysine N-methyltransferase EZH2 [KO:K11430] [EC:2.1.1.356]
127428338  histone-lysine N-methyltransferase SETMAR-like isoform X1 [KO:K11433] [EC:2.1.1.357]
127431017  histone-lysine N-methyltransferase NSD2-like [KO:K15588] [EC:2.1.1.357]
127413112  histone-lysine N-methyltransferase, H3 lysine-36 specific-like [KO:K15588] [EC:2.1.1.357]
127429312  histone-lysine N-methyltransferase, H3 lysine-36 specific-like [KO:K15588] [EC:2.1.1.357]
127417885  histone-lysine N-methyltransferase NSD2-like isoform X1 [KO:K15588] [EC:2.1.1.357]
127412226  histone-lysine N-methyltransferase NSD2-like isoform X1 [KO:K11424] [EC:2.1.1.357]
127414253  histone-lysine N-methyltransferase NSD2-like isoform X1 [KO:K11424] [EC:2.1.1.357]
127432704  histone-lysine N-methyltransferase NSD3-like isoform X1 [KO:K11425] [EC:2.1.1.370 2.1.1.371]
127433635  histone-lysine N-methyltransferase NSD3-like isoform X1 [KO:K11425] [EC:2.1.1.370 2.1.1.371]
127454335  histone-lysine N-methyltransferase SETD2-like isoform X1 [KO:K11423] [EC:2.1.1.359]
127437915  histone-lysine N-methyltransferase, H3 lysine-79 specific-like isoform X1 [KO:K11427] [EC:2.1.1.360]
127439273  histone-lysine N-methyltransferase, H3 lysine-79 specific-like isoform X1 [KO:K11427] [EC:2.1.1.360]
127432609  N-lysine methyltransferase KMT5A-A-like [KO:K11428] [EC:2.1.1.361]
127433711  N-lysine methyltransferase KMT5A-A-like isoform X1 [KO:K11428] [EC:2.1.1.361]
127436002  lysine methyltransferase 5Ab [KO:K11428] [EC:2.1.1.361]
127414562  putative histone-lysine N-methyltransferase PRDM6 isoform X1 [KO:K20795] [EC:2.1.1.361]
127423857  putative histone-lysine N-methyltransferase PRDM6 [KO:K20795] [EC:2.1.1.361]
127456131  histone-lysine N-methyltransferase KMT5B-like [KO:K11429] [EC:2.1.1.362]
127416989  histone-lysine N-methyltransferase KMT5B [KO:K11429] [EC:2.1.1.362]
127422432  MDS1 and EVI1 complex locus protein EVI1-A-like [KO:K04462] [EC:2.1.1.367]
127430167  MDS1 and EVI1 complex locus protein EVI1-A-like isoform X1 [KO:K04462] [EC:2.1.1.367]
127424664  histone-lysine N-methyltransferase PRDM16-like [KO:K22410] [EC:2.1.1.367]
127414438  histone-lysine N-methyltransferase PRDM16-like [KO:K22410] [EC:2.1.1.367]
127430672  trimethyllysine dioxygenase, mitochondrial-like [KO:K00474] [EC:1.14.11.8]
127429350  trimethyllysine dioxygenase, mitochondrial-like [KO:K00474] [EC:1.14.11.8]
127431038  aldehyde dehydrogenase family 3 member A2-like isoform X1 [KO:K00128] [EC:1.2.1.3]
127449938  aldehyde dehydrogenase family 16 member A1-like isoform X1 [KO:K00128] [EC:1.2.1.3]
127451346  aldehyde dehydrogenase family 16 member A1 isoform X1 [KO:K00128] [EC:1.2.1.3]
127422570  aldehyde dehydrogenase family 3 member A2a [KO:K00128] [EC:1.2.1.3]
127429187  aldehyde dehydrogenase family 3 member A2-like [KO:K00128] [EC:1.2.1.3]
127429738  aldehyde dehydrogenase family 3 member A2 [KO:K00128] [EC:1.2.1.3]
127435818  aldehyde dehydrogenase 2 family member, tandem duplicate 2 isoform X1 [KO:K00128] [EC:1.2.1.3]
127414608  4-trimethylaminobutyraldehyde dehydrogenase A-like [KO:K00149] [EC:1.2.1.47 1.2.1.3]
127441089  4-trimethylaminobutyraldehyde dehydrogenase B [KO:K00149] [EC:1.2.1.47 1.2.1.3]
127442640  4-trimethylaminobutyraldehyde dehydrogenase B [KO:K00149] [EC:1.2.1.47 1.2.1.3]
127424099  4-trimethylaminobutyraldehyde dehydrogenase A [KO:K00149] [EC:1.2.1.47 1.2.1.3]
127446986  gamma-butyrobetaine dioxygenase-like [KO:K00471] [EC:1.14.11.1]
127415608  gamma-butyrobetaine dioxygenase-like [KO:K00471] [EC:1.14.11.1]
127424395  procollagen-lysine,2-oxoglutarate 5-dioxygenase 1-like [KO:K00473] [EC:1.14.11.4]
127414474  procollagen-lysine,2-oxoglutarate 5-dioxygenase 1-like [KO:K00473] [EC:1.14.11.4]
127431646  procollagen-lysine,2-oxoglutarate 5-dioxygenase 2-like isoform X1 [KO:K13645] [EC:1.14.11.4]
127434416  procollagen-lysine,2-oxoglutarate 5-dioxygenase 2-like isoform X1 [KO:K13645] [EC:1.14.11.4]
127419328  multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3-like [KO:K13646] [EC:1.14.11.4 2.4.1.50 2.4.1.66]
127419824  multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 isoform X1 [KO:K13646] [EC:1.14.11.4 2.4.1.50 2.4.1.66]
127424447  procollagen galactosyltransferase 2-like isoform X1 [KO:K11703] [EC:2.4.1.50]
127444162  procollagen galactosyltransferase 1 [KO:K11703] [EC:2.4.1.50]
127450831  procollagen galactosyltransferase 1 [KO:K11703] [EC:2.4.1.50]
127432972  probable inactive glycosyltransferase 25 family member 3 [KO:K11703] [EC:2.4.1.50]
127451717  procollagen galactosyltransferase 1-like [KO:K11703] [EC:2.4.1.50]
127415238  procollagen galactosyltransferase 2-like [KO:K11703] [EC:2.4.1.50]
127433870  probable inactive glycosyltransferase 25 family member 3 [KO:K11703] [EC:2.4.1.50]
127443065  procollagen galactosyltransferase 2 [KO:K11703] [EC:2.4.1.50]
Compound
C00024  Acetyl-CoA
C00026  2-Oxoglutarate
C00037  Glycine
C00042  Succinate
C00047  L-Lysine
C00068  Thiamin diphosphate
C00136  Butanoyl-CoA
C00164  Acetoacetate
C00322  2-Oxoadipate
C00332  Acetoacetyl-CoA
C00408  L-Pipecolate
C00431  5-Aminopentanoate
C00449  N6-(L-1,3-Dicarboxypropyl)-L-lysine
C00450  (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate
C00487  Carnitine
C00489  Glutarate
C00527  Glutaryl-CoA
C00739  D-Lysine
C00877  Crotonoyl-CoA
C00956  L-2-Aminoadipate
C00990  5-Aminopentanamide
C01087  (R)-2-Hydroxyglutarate
C01142  (3S)-3,6-Diaminohexanoate
C01144  (S)-3-Hydroxybutanoyl-CoA
C01149  4-Trimethylammoniobutanal
C01181  4-Trimethylammoniobutanoate
C01186  (3S,5S)-3,5-Diaminohexanoate
C01211  Procollagen 5-hydroxy-L-lysine
C01259  (3S)-3-Hydroxy-N6,N6,N6-trimethyl-L-lysine
C01672  Cadaverine
C02188  Protein lysine
C02727  N6-Acetyl-L-lysine
C03087  5-Acetamidopentanoate
C03196  (S)-2-Hydroxyglutarate
C03239  6-Amino-2-oxohexanoate
C03273  5-Oxopentanoate
C03366  5-Phosphooxy-L-lysine
C03656  (S)-5-Amino-3-oxohexanoic acid
C03793  N6,N6,N6-Trimethyl-L-lysine
C04020  D-Lysopine
C04076  L-2-Aminoadipate 6-semialdehyde
C04092  Delta1-Piperideine-2-carboxylate
C04487  5-(D-Galactosyloxy)-L-lysine-procollagen
C05161  (2R,5S)-2,5-Diaminohexanoate
C05231  L-3-Aminobutyryl-CoA
C05544  Protein N6-methyl-L-lysine
C05545  Protein N6,N6-dimethyl-L-lysine
C05546  Protein N6,N6,N6-trimethyl-L-lysine
C05548  6-Acetamido-2-oxohexanoate
C05825  2-Amino-5-oxohexanoate
C06157  [Dihydrolipoyllysine-residue succinyltransferase] S-glutaryldihydrolipoyllysine
C12455  5-Aminopentanal
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16741  L-Hydroxylysine
C22667  4-Carboxy-1-hydroxybutyryl-ThPP
Reference
PMID:11802770
  Authors
Vaz FM, Wanders RJ.
  Title
Carnitine biosynthesis in mammals.
  Journal
Biochem J 361:417-29 (2002)
DOI:10.1042/bj3610417
Reference
PMID:1682209
  Authors
Large PJ, Robertson A.
  Title
The route of lysine breakdown in Candida tropicalis.
  Journal
FEMS Microbiol Lett 66:209-13 (1991)
DOI:10.1111/j.1574-6968.1990.tb03998.x
Related
pathway
masi00020  Citrate cycle (TCA cycle)
masi00780  Biotin metabolism
KO pathway
ko00310   
LinkDB

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