KEGG   PATHWAY: ogo04142
Entry
ogo04142                    Pathway                                
Name
Lysosome - Oncorhynchus gorbuscha (pink salmon)
Description
Lysosomes are membrane-delimited organelles in animal cells serving as the cell's main digestive compartment to which all sorts of macromolecules are delivered for degradation. They contain more than 40 hydrolases in an acidic environment (pH of about 5). After synthesis in the ER, lysosomal enzymes are decorated with mannose-6-phosphate residues, which are recognized by mannose-6-phosphate receptors in the trans-Golgi network. They are packaged into clathrin-coated vesicles and are transported to late endosomes. Substances for digestion are acquired by the lysosomes via a series of processes including endocytosis, phagocytosis, and autophagy.
Class
Cellular Processes; Transport and catabolism
Pathway map
ogo04142  Lysosome
ogo04142

Other DBs
GO: 0005764
Organism
Oncorhynchus gorbuscha (pink salmon) [GN:ogo]
Gene
123990275  si:ch73-173p19.2; V-type proton ATPase 116 kDa subunit a1 isoform X1 [KO:K02154]
123993316  LOW QUALITY PROTEIN: V-type proton ATPase 116 kDa subunit a3-like [KO:K02154]
124047851  V-type proton ATPase 116 kDa subunit a2-like [KO:K02154]
124034267  V-type proton ATPase 116 kDa subunit a2-like isoform X1 [KO:K02154]
124048435  V-type proton ATPase 116 kDa subunit a1-like isoform X1 [KO:K02154]
123999207  V-type proton ATPase 116 kDa subunit a1-like isoform X1 [KO:K02154]
124013297  tcirg1a; LOW QUALITY PROTEIN: V-type proton ATPase 116 kDa subunit a3 [KO:K02154]
124036369  V-type proton ATPase 116 kDa subunit a2-like [KO:K02154]
124007173  V-type proton ATPase 116 kDa subunit a2-like isoform X1 [KO:K02154]
124015470  V-type proton ATPase 116 kDa subunit a1-like isoform X1 [KO:K02154]
124009959  V-type proton ATPase subunit d 1-like [KO:K02146]
124035471  V-type proton ATPase subunit d 1 [KO:K02146]
124026981  V-type proton ATPase subunit d 1 [KO:K02146]
124009647  atp6v1h; V-type proton ATPase subunit H isoform X1 [KO:K02144]
124040708  V-type proton ATPase subunit H-like [KO:K02144]
124026772  V-type proton ATPase subunit S1-like [KO:K03662]
124046029  V-type proton ATPase subunit S1-like [KO:K03662]
124032211  V-type proton ATPase subunit S1-like [KO:K03662]
124032439  atp6ap1a; ATPase H+ transporting accessory protein 1a isoform X1 [KO:K03662]
124039922  V-type proton ATPase 16 kDa proteolipid subunit [KO:K02155]
124048376  atp6v0cb; ATPase H+ transporting V0 subunit cb [KO:K02155]
124000281  atp6v0ca; ATPase H+ transporting V0 subunit ca [KO:K02155]
124037923  V-type proton ATPase 16 kDa proteolipid subunit [KO:K02155]
124041861  atp6v0b; V-type proton ATPase 21 kDa proteolipid subunit [KO:K03661]
124009392  V-type proton ATPase 21 kDa proteolipid subunit [KO:K03661]
124034632  dmX-like protein 1 isoform X1 [KO:K24155]
124017829  dmxl2; dmX-like protein 2 isoform X1 [KO:K24155]
123989545  WD repeat-containing protein 7 isoform X1 [KO:K24738]
123990849  nuclear receptor coactivator 7-like isoform X1 [KO:K25442]
123995186  nuclear receptor coactivator 7-like isoform X1 [KO:K25442]
124001265  si:ch211-15d5.11; nuclear receptor coactivator 7 isoform X1 [KO:K25442]
124046275  nuclear receptor coactivator 7-like isoform X1 [KO:K25442]
124035690  lysosomal protective protein-like [KO:K13289] [EC:3.4.16.5]
124026161  ctsa; lysosomal protective protein [KO:K13289] [EC:3.4.16.5]
124033111  lysosomal protective protein-like [KO:K13289] [EC:3.4.16.5]
123995189  ctsbb; cathepsin Bb [KO:K01363] [EC:3.4.22.1]
124001459  cathepsin B-like [KO:K01363] [EC:3.4.22.1]
124046724  ctsba; cathepsin B [KO:K01363] [EC:3.4.22.1]
124006275  dipeptidyl peptidase 1-like [KO:K01275] [EC:3.4.14.1]
124006475  dipeptidyl peptidase 1-like [KO:K01275] [EC:3.4.14.1]
124019850  cathepsin D-like isoform X1 [KO:K01379] [EC:3.4.23.5]
124019880  cathepsin D-like isoform X1 [KO:K01379] [EC:3.4.23.5]
123998568  cathepsin D-like isoform X1 [KO:K01379] [EC:3.4.23.5]
124024511  cathepsin D-like isoform X1 [KO:K01379] [EC:3.4.23.5]
124015511  napsa; LOW QUALITY PROTEIN: napsin-A [KO:K01379] [EC:3.4.23.5]
124019765  LOW QUALITY PROTEIN: cathepsin D-like [KO:K01382] [EC:3.4.23.34]
123993592  cathepsin F-like isoform X1 [KO:K01373] [EC:3.4.22.41]
124011096  cathepsin F-like isoform X1 [KO:K01373] [EC:3.4.22.41]
124035003  pro-cathepsin H-like isoform X1 [KO:K01366] [EC:3.4.22.16]
124036427  ctsh; pro-cathepsin H [KO:K01366] [EC:3.4.22.16]
123997752  ctsk; cathepsin K [KO:K01371] [EC:3.4.22.38]
124006230  cathepsin K-like [KO:K01371] [EC:3.4.22.38]
124047777  procathepsin L-like [KO:K01365] [EC:3.4.22.15]
124047778  procathepsin L-like [KO:K01365] [EC:3.4.22.15]
124047780  procathepsin L-like [KO:K01365] [EC:3.4.22.15]
124047781  procathepsin L-like [KO:K01365] [EC:3.4.22.15]
124048614  procathepsin L-like [KO:K01365] [EC:3.4.22.15]
124048615  procathepsin L-like [KO:K01365] [EC:3.4.22.15]
123999588  LOW QUALITY PROTEIN: procathepsin L-like [KO:K01365] [EC:3.4.22.15]
124037743  cts12; procathepsin L [KO:K01365] [EC:3.4.22.15]
124001749  ctsl.1; cathepsin L.1 [KO:K01365] [EC:3.4.22.15]
124004113  procathepsin L-like [KO:K01365] [EC:3.4.22.15]
123993507  ctso; cathepsin O [KO:K01374] [EC:3.4.22.42]
123997753  cathepsin S-like [KO:K01368] [EC:3.4.22.27]
124006231  cathepsin S-like [KO:K01368] [EC:3.4.22.27]
124002606  cathepsin Z-like [KO:K08568] [EC:3.4.18.1]
124009860  cathepsin Z [KO:K08568] [EC:3.4.18.1]
124031150  cathepsin Z-like [KO:K08568] [EC:3.4.18.1]
124046780  LOW QUALITY PROTEIN: legumain-like [KO:K01369] [EC:3.4.22.34]
124046214  tpp1; tripeptidyl-peptidase 1 [KO:K01279] [EC:3.4.14.9]
123993576  gla; alpha-galactosidase A [KO:K01189] [EC:3.2.1.22]
124012350  glb1; beta-galactosidase [KO:K12309] [EC:3.2.1.23]
124003753  lysosomal alpha-glucosidase-like [KO:K12316] [EC:3.2.1.20]
124025282  LOW QUALITY PROTEIN: lysosomal alpha-glucosidase-like [KO:K12316] [EC:3.2.1.20]
123998196  gba; lysosomal acid glucosylceramidase [KO:K01201] [EC:3.2.1.45]
124036455  idua; alpha-L-iduronidase isoform X1 [KO:K01217] [EC:3.2.1.76]
123991645  alpha-N-acetylgalactosaminidase-like [KO:K01204] [EC:3.2.1.49]
123997615  alpha-N-acetylgalactosaminidase-like [KO:K01204] [EC:3.2.1.49]
124048436  naglu; LOW QUALITY PROTEIN: alpha-N-acetylglucosaminidase [KO:K01205] [EC:3.2.1.50]
124001517  galcb; galactocerebrosidase isoform X1 [KO:K01202] [EC:3.2.1.46]
123999507  beta-glucuronidase-like [KO:K01195] [EC:3.2.1.31]
124014924  beta-glucuronidase-like [KO:K01195] [EC:3.2.1.31]
124013076  tissue alpha-L-fucosidase-like [KO:K01206] [EC:3.2.1.51]
124043129  tissue alpha-L-fucosidase-like [KO:K01206] [EC:3.2.1.51]
124029225  tissue alpha-L-fucosidase-like [KO:K01206] [EC:3.2.1.51]
124030261  tissue alpha-L-fucosidase-like [KO:K01206] [EC:3.2.1.51]
124001274  fuca2; plasma alpha-L-fucosidase [KO:K01206] [EC:3.2.1.51]
123989307  beta-hexosaminidase subunit beta-like isoform X1 [KO:K12373] [EC:3.2.1.52]
124007037  hexb; beta-hexosaminidase subunit beta isoform X1 [KO:K12373] [EC:3.2.1.52]
124031501  hexa; beta-hexosaminidase subunit alpha [KO:K12373] [EC:3.2.1.52]
124002265  manba; beta-mannosidase [KO:K01192] [EC:3.2.1.25]
124018621  man2b1; lysosomal alpha-mannosidase isoform X1 [KO:K12311] [EC:3.2.1.24]
124018633  LOW QUALITY PROTEIN: lysosomal alpha-mannosidase-like [KO:K12311] [EC:3.2.1.24]
124020031  sialidase-1-like [KO:K01186] [EC:3.2.1.18]
124012789  sialidase-1-like [KO:K01186] [EC:3.2.1.18]
123995503  hyaluronidase PH-20-like [KO:K01197] [EC:3.2.1.35]
124003069  hyal1; hyaluronidase-1 [KO:K01197] [EC:3.2.1.35]
124003117  hyaluronidase-2-like [KO:K01197] [EC:3.2.1.35]
124003394  hyaluronidase-2-like [KO:K01197] [EC:3.2.1.35]
124010034  hyaluronidase-like [KO:K01197] [EC:3.2.1.35]
124010113  hyaluronidase-4-like [KO:K01197] [EC:3.2.1.35]
124010185  hyaluronidase-5-like isoform X1 [KO:K01197] [EC:3.2.1.35]
124037024  hyaluronidase-5-like [KO:K01197] [EC:3.2.1.35]
124027884  hyaluronidase-2-like [KO:K01197] [EC:3.2.1.35]
124037592  hyaluronidase-4-like [KO:K01197] [EC:3.2.1.35]
124045745  hyal3; hyaluronidase-3 isoform X1 [KO:K01197] [EC:3.2.1.35]
124031551  hyaluronidase-2-like [KO:K01197] [EC:3.2.1.35]
124031773  si:dkey-72l14.3; glyco_hydro_56 domain-containing protein [KO:K01197] [EC:3.2.1.35]
124035886  arsa; arylsulfatase A [KO:K01134] [EC:3.1.6.8]
124007397  arsb; arylsulfatase B [KO:K01135] [EC:3.1.6.12]
124040212  arylsulfatase G-like [KO:K12381] [EC:3.1.6.-]
124033834  galns; N-acetylgalactosamine-6-sulfatase isoform X1 [KO:K01132] [EC:3.1.6.4]
123989342  gnsb; glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), b [KO:K01137] [EC:3.1.6.14]
124019611  LOW QUALITY PROTEIN: N-acetylglucosamine-6-sulfatase-like [KO:K01137] [EC:3.1.6.14]
124010384  ids; iduronate 2-sulfatase isoform X1 [KO:K01136] [EC:3.1.6.13]
124002725  sgsh; N-sulphoglucosamine sulphohydrolase [KO:K01565] [EC:3.10.1.1]
124040035  lysosomal acid lipase/cholesteryl ester hydrolase-like [KO:K01052] [EC:3.1.1.13]
124048161  lipf; gastric triacylglycerol lipase [KO:K01052] [EC:3.1.1.13]
123999641  phospholipase A2 group XV-like [KO:K06129] [EC:3.1.1.5]
124038033  phospholipase A2 group XV-like isoform X1 [KO:K06129] [EC:3.1.1.5]
123996736  deoxyribonuclease-2-alpha-like isoform X1 [KO:K01158] [EC:3.1.22.1]
124005231  deoxyribonuclease-2-alpha-like [KO:K01158] [EC:3.1.22.1]
124033925  lysosomal acid phosphatase-like [KO:K14410] [EC:3.1.3.2]
124035895  lysosomal acid phosphatase-like isoform X1 [KO:K14410] [EC:3.1.3.2]
124004012  acp5a; tartrate-resistant acid phosphatase type 5a [KO:K14379] [EC:3.1.3.2]
124039457  tartrate-resistant acid phosphatase type 5-like [KO:K14379] [EC:3.1.3.2]
124007125  smpd1; sphingomyelin phosphodiesterase [KO:K12350] [EC:3.1.4.12]
124012346  acid ceramidase-like [KO:K12348] [EC:3.5.1.23]
124002212  acid ceramidase-like [KO:K12348] [EC:3.5.1.23]
123993501  aga; N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase [KO:K01444] [EC:3.5.1.26]
124038207  zgc:153169; N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase isoform X1 [KO:K01444] [EC:3.5.1.26]
124040450  prosaposin-like isoform X1 [KO:K12382]
124048065  prosaposin-like [KO:K12382]
124034285  sftpbb; surfactant protein Bb [KO:K12382]
124006943  sftpba; prosaposin [KO:K12382]
124048848  prosaposin-like isoform X1 [KO:K12382]
123993717  ganglioside GM2 activator-like [KO:K12383]
124011597  ganglioside GM2 activator-like [KO:K12383]
124020678  lysosomal thioesterase PPT2-A-like [KO:K01074] [EC:3.1.2.22]
124012053  palmitoyl-protein thioesterase 1-like [KO:K01074] [EC:3.1.2.22]
124013176  lysosomal thioesterase PPT2-A-like [KO:K01074] [EC:3.1.2.22]
124043624  palmitoyl-protein thioesterase 1-like [KO:K01074] [EC:3.1.2.22]
124043650  lysosomal thioesterase PPT2-A-like isoform X1 [KO:K01074] [EC:3.1.2.22]
123993538  lysosome-associated membrane glycoprotein 2-like isoform X1 [KO:K06528]
124010489  lamp2; lysosome-associated membrane glycoprotein 2 isoform X1 [KO:K06528]
124024839  LOW QUALITY PROTEIN: lysosome-associated membrane glycoprotein 1-like [KO:K06528]
124026379  lysosome-associated membrane glycoprotein 1-like [KO:K06528]
124027392  lysosome-associated membrane glycoprotein 1-like [KO:K06528]
124044211  lysosome-associated membrane glycoprotein 1-like [KO:K06528]
124044284  lysosome-associated membrane glycoprotein 1-like [KO:K06528]
123996910  lysosome-associated membrane glycoprotein 3-like [KO:K06562]
124037796  lysosome-associated membrane glycoprotein 3 [KO:K06562]
124014017  cd68; salivary glue protein Sgs-3 [KO:K06501]
124045963  CD63 antigen-like [KO:K06497]
124032147  CD63 antigen-like [KO:K06497]
124048663  lysosome membrane protein 2-like [KO:K12384]
124034488  scarb2a; lysosome membrane protein 2a isoform X1 [KO:K12384]
124036112  lysosome membrane protein 2-like [KO:K12384]
123999425  lysosome membrane protein 2-like [KO:K12384]
123999426  scarb2c; lysosome membrane protein 2c [KO:K12384]
124009654  npc1; NPC intracellular cholesterol transporter 1 [KO:K12385]
124041723  NPC intracellular cholesterol transporter 1-like [KO:K12385]
124001117  NPC intracellular cholesterol transporter 2-like [KO:K13443]
123997204  cystinosin-like [KO:K12386]
123991653  cystinosin-like [KO:K12386]
124041275  slc17a5; sialin isoform X1 [KO:K12301]
124012052  sialin-like [KO:K12301]
124043622  sialin-like [KO:K12301]
124002618  natural resistance-associated macrophage protein 2-like isoform X1 [KO:K21398]
124031181  natural resistance-associated macrophage protein 2-like isoform X1 [KO:K21398]
123990562  laptm4a; lysosomal-associated transmembrane protein 4A [KO:K12387]
123994838  lysosomal-associated transmembrane protein 4A-like isoform X1 [KO:K12387]
123998102  lysosomal-associated transmembrane protein 4B-like isoform X1 [KO:K12387]
124006425  lysosomal-associated transmembrane protein 4B-like isoform X1 [KO:K12387]
124034069  ATP-binding cassette sub-family A member 2-like isoform X1 [KO:K05642]
124036568  LOW QUALITY PROTEIN: ATP-binding cassette sub-family A member 2-like [KO:K05642]
124033242  abcb9; ATP-binding cassette sub-family B member 9 [KO:K05656]
124036503  LOW QUALITY PROTEIN: ABC-type oligopeptide transporter ABCB9-like [KO:K05656]
123991037  sialomucin core protein 24-like isoform X1 [KO:K06546]
123995255  sialomucin core protein 24-like isoform X1 [KO:K06546]
124034342  ectonucleoside triphosphate diphosphohydrolase 4-like isoform X1 [KO:K12305] [EC:3.6.1.6]
124034915  ectonucleoside triphosphate diphosphohydrolase 4-like [KO:K12305] [EC:3.6.1.6]
123994379  sortilin-like [KO:K12388]
124014166  sortilin-like [KO:K12388]
124045475  sortilin-like [KO:K12388]
124031356  sort1a; sortilin [KO:K12388]
124032372  sortilin-like [KO:K12388]
124000777  cln3; LOW QUALITY PROTEIN: battenin [KO:K12389]
124014459  cln5; ceroid-lipofuscinosis neuronal protein 5 isoform X1 [KO:K12390]
123995486  uncharacterized protein LOC123995486 [KO:K12307]
124009798  mfsd8l2; uncharacterized protein mfsd8l2 [KO:K12307]
124014275  mfsd8; major facilitator superfamily domain-containing protein 8 isoform X1 [KO:K12307]
124018032  heparan-alpha-glucosaminide N-acetyltransferase-like [KO:K10532] [EC:2.3.1.78]
124018041  heparan-alpha-glucosaminide N-acetyltransferase-like isoform X1 [KO:K10532] [EC:2.3.1.78]
124018042  heparan-alpha-glucosaminide N-acetyltransferase-like isoform X1 [KO:K10532] [EC:2.3.1.78]
124041438  si:dkey-192p21.6; heparan-alpha-glucosaminide N-acetyltransferase [KO:K10532] [EC:2.3.1.78]
124029691  LOW QUALITY PROTEIN: heparan-alpha-glucosaminide N-acetyltransferase-like [KO:K10532] [EC:2.3.1.78]
124003442  sumf1; formylglycine-generating enzyme isoform X1 [KO:K13444] [EC:1.8.3.7]
123994493  N-acetylglucosamine-1-phosphotransferase subunits alpha/beta-like [KO:K08239] [EC:2.7.8.17]
124013741  N-acetylglucosamine-1-phosphotransferase subunits alpha/beta-like [KO:K08239] [EC:2.7.8.17]
124048344  gnptg; N-acetylglucosamine-1-phosphotransferase subunit gamma [KO:K10087]
123997793  nagpa; N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase [KO:K01125] [EC:3.1.4.45]
123990742  LOW QUALITY PROTEIN: cation-independent mannose-6-phosphate receptor-like [KO:K06564]
123995079  cation-independent mannose-6-phosphate receptor-like [KO:K06564]
124004742  m6pr; cation-dependent mannose-6-phosphate receptor [KO:K10089]
123998120  cation-dependent mannose-6-phosphate receptor-like [KO:K10089]
124012576  clathrin light chain A-like isoform X1 [KO:K04644]
124001820  clathrin light chain A-like isoform X1 [KO:K04644]
123993768  cltb; clathrin light chain B [KO:K04645]
124011575  clathrin light chain A-like [KO:K04645]
123992666  clathrin heavy chain 1-like isoform X1 [KO:K04646]
124010579  clathrin heavy chain 1-like isoform X1 [KO:K04646]
123998623  clathrin heavy chain 1 isoform X1 [KO:K04646]
124005512  clathrin heavy chain 1-like isoform X1 [KO:K04646]
124036435  clathrin heavy chain 1-like [KO:K04646]
124033754  AP-1 complex subunit gamma-1-like isoform X1 [KO:K12391]
124041585  ap1g2; AP-1 complex subunit gamma-like 2 [KO:K12391]
124035736  AP-1 complex subunit gamma-1 isoform X1 [KO:K12391]
124009588  AP-1 complex subunit gamma-1-like isoform X1 [KO:K12391]
124034273  AP-1 complex subunit beta-1 isoform X1 [KO:K12392]
124036362  LOW QUALITY PROTEIN: AP-1 complex subunit beta-1-like [KO:K12392]
123997145  AP-1 complex subunit mu-1 isoform X1 [KO:K12393]
123997971  AP-1 complex subunit mu-1-like [KO:K12393]
123998839  AP-1 complex subunit mu-1 [KO:K12393]
124038014  AP-1 complex subunit mu-2-like [KO:K12393]
124016464  ap1m2; AP-1 complex subunit mu-2 [KO:K12393]
124016517  AP-1 complex subunit mu-2 [KO:K12393]
123997213  AP-1 complex subunit sigma-2-like [KO:K12394]
124018961  AP-1 complex subunit sigma-2-like [KO:K12394]
124018974  AP-1 complex subunit sigma-2 isoform X1 [KO:K12394]
124020585  AP-1 complex subunit sigma-2-like [KO:K12394]
124014024  AP-1 complex subunit sigma-1A [KO:K12394]
124007859  AP-1 complex subunit sigma-1A-like [KO:K12394]
123992254  uncharacterized protein LOC123992254 [KO:K12395]
124009653  AP-1 complex subunit sigma-2-like isoform X1 [KO:K12395]
124041644  AP-1 complex subunit sigma-2-like isoform X1 [KO:K12395]
124005275  AP-1 complex subunit sigma-3-like [KO:K12395]
123997049  AP-3 complex subunit delta-1-like isoform X1 [KO:K12396]
124037693  AP-3 complex subunit delta-1-like isoform X1 [KO:K12396]
124040149  AP-3 complex subunit beta-2 isoform X1 [KO:K12397]
124049087  LOW QUALITY PROTEIN: AP-3 complex subunit beta-1-like [KO:K12397]
124006749  ap3b1a; AP-3 complex subunit beta-1 [KO:K12397]
124034169  AP-3 complex subunit mu-2 [KO:K12398]
124020492  AP-3 complex subunit mu-1-like isoform X1 [KO:K12398]
124036478  LOW QUALITY PROTEIN: AP-3 complex subunit mu-2-like [KO:K12398]
124034636  AP-3 complex subunit sigma-1-like [KO:K12399]
124021466  ap3s2; AP-3 complex subunit sigma-2 [KO:K12399]
124035973  AP-3 complex subunit sigma-1 isoform X1 [KO:K12399]
124027948  AP-3 complex subunit sigma-2-like [KO:K12399]
124037485  ap4e1; AP-4 complex subunit epsilon-1 [KO:K12400]
124018239  ap4b1; AP-4 complex subunit beta-1 [KO:K12401]
124009987  ap4m1; AP-4 complex subunit mu-1 [KO:K12402]
124001263  ap4s1; AP-4 complex subunit sigma-1 [KO:K12403]
124003257  LOW QUALITY PROTEIN: ADP-ribosylation factor-binding protein GGA3-like [KO:K12404]
124003798  ADP-ribosylation factor-binding protein GGA1-like isoform X1 [KO:K12404]
124019558  ADP-ribosylation factor-binding protein GGA2-like [KO:K12404]
124022058  LOW QUALITY PROTEIN: ADP-ribosylation factor-binding protein GGA3-like [KO:K12404]
123998905  ADP-ribosylation factor-binding protein GGA3-like [KO:K12404]
123999232  ADP-ribosylation factor-binding protein GGA1-like [KO:K12404]
124015603  ADP-ribosylation factor-binding protein GGA3-like [KO:K12404]
124015707  ADP-ribosylation factor-binding protein GGA1-like [KO:K12404]
124016134  ADP-ribosylation factor-binding protein GGA1-like isoform X1 [KO:K12404]
124003965  mucolipin-1-like [KO:K04992]
124015497  mucolipin-1-like isoform X1 [KO:K04992]
124015758  mucolipin-1-like [KO:K04992]
124002801  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog [KO:K19363]
124040167  uncharacterized protein LOC124040167 [KO:K19363]
124019909  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog [KO:K19363]
124019912  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog isoform X1 [KO:K19363]
124023959  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog [KO:K19363]
124024241  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog [KO:K19363]
124025450  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog [KO:K19363]
124025619  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog [KO:K19363]
123999720  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog [KO:K19363]
124027405  LITAF domain-containing protein-like isoform X1 [KO:K19363]
124015082  litaf; lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog [KO:K19363]
124015957  uncharacterized protein LOC124015957 isoform X1 [KO:K19363]
Compound
C00002  ATP
C00008  ADP
C00159  D-Mannose
C00275  D-Mannose 6-phosphate
Reference
PMID:12628346
  Authors
Eskelinen EL, Tanaka Y, Saftig P
  Title
At the acidic edge: emerging functions for lysosomal membrane proteins.
  Journal
Trends Cell Biol 13:137-45 (2003)
DOI:10.1016/S0962-8924(03)00005-9
Reference
PMID:1883197
  Authors
Neufeld EF
  Title
Lysosomal storage diseases.
  Journal
Annu Rev Biochem 60:257-80 (1991)
DOI:10.1146/annurev.bi.60.070191.001353
Reference
PMID:2943218
  Authors
von Figura K, Hasilik A
  Title
Lysosomal enzymes and their receptors.
  Journal
Annu Rev Biochem 55:167-93 (1986)
DOI:10.1146/annurev.bi.55.070186.001123
Reference
PMID:15987739
  Authors
Janvier K, Bonifacino JS
  Title
Role of the endocytic machinery in the sorting of lysosome-associated membrane proteins.
  Journal
Mol Biol Cell 16:4231-42 (2005)
DOI:10.1091/mbc.E05-03-0213
Reference
PMID:18635948
  Authors
Vergarajauregui S, Puertollano R
  Title
Mucolipidosis type IV: the importance of functional lysosomes for efficient autophagy.
  Journal
Autophagy 4:832-4 (2008)
DOI:10.4161/auto.6567
Reference
PMID:34249946
  Authors
Jaskolka MC, Winkley SR, Kane PM
  Title
RAVE and Rabconnectin-3 Complexes as Signal Dependent Regulators of Organelle Acidification.
  Journal
Front Cell Dev Biol 9:698190 (2021)
DOI:10.3389/fcell.2021.698190
Reference
PMID:34646033
  Authors
Majdoul S, Compton AA
  Title
Lessons in self-defence: inhibition of virus entry by intrinsic immunity.
  Journal
Nat Rev Immunol 10.1038/s41577-021-00626-8 (2021)
DOI:10.1038/s41577-021-00626-8
Related
pathway
ogo00511  Other glycan degradation
ogo00531  Glycosaminoglycan degradation
ogo04130  SNARE interactions in vesicular transport
ogo04140  Autophagy - animal
ogo04144  Endocytosis
KO pathway
ko04142   
LinkDB

DBGET integrated database retrieval system