KEGG   PATHWAY: pfor00230
Entry
pfor00230                   Pathway                                
Name
Purine metabolism - Poecilia formosa (Amazon molly)
Class
Metabolism; Nucleotide metabolism
Pathway map
pfor00230  Purine metabolism
pfor00230

Module
pfor_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:pfor00230]
pfor_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:pfor00230]
pfor_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:pfor00230]
pfor_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:pfor00230]
pfor_M00546  Purine degradation, xanthine => urea [PATH:pfor00230]
pfor_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:pfor00230]
pfor_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:pfor00230]
Other DBs
GO: 0006163 0042278
Organism
Poecilia formosa (Amazon molly) [GN:pfor]
Gene
103129312  ak6; adenylate kinase isoenzyme 6 isoform X1 [KO:K18532] [EC:2.7.4.3]
103129619  [KO:K08041] [EC:4.6.1.1]
103129697  ampd1; AMP deaminase 1 isoform X1 [KO:K01490] [EC:3.5.4.6]
103130136  [KO:K01466] [EC:3.5.2.5]
103130226  [KO:K13761] [EC:3.1.4.35]
103130371  nt5e; 5'-nucleotidase [KO:K19970] [EC:3.1.3.5]
103130762  [KO:K13293] [EC:3.1.4.53]
103130861  [KO:K00365] [EC:1.7.3.3]
103130884  [KO:K00365] [EC:1.7.3.3]
103131040  [KO:K08049] [EC:4.6.1.1]
103131082  [KO:K12320] [EC:4.6.1.2]
103131147  [KO:K03783] [EC:2.4.2.1]
103131327  [KO:K01511] [EC:3.6.1.6]
103131428  prune; protein prune homolog [KO:K01514] [EC:3.6.1.11]
103131434  [KO:K12323] [EC:4.6.1.2]
103131439  [KO:K12323] [EC:4.6.1.2]
103131446  ak8; adenylate kinase 8 [KO:K00939] [EC:2.7.4.3]
103131482  [KO:K01081] [EC:3.1.3.5]
103133503  [KO:K01081] [EC:3.1.3.5]
103133528  [KO:K13811] [EC:2.7.7.4 2.7.1.25]
103133663  entpd3; ectonucleoside triphosphate diphosphohydrolase 3 isoform X1 [KO:K01510] [EC:3.6.1.5]
103133729  [KO:K00760] [EC:2.4.2.8]
103133763  impdh1; inosine-5'-monophosphate dehydrogenase 1 isoform X1 [KO:K00088] [EC:1.1.1.205]
103133900  [KO:K01939] [EC:6.3.4.4]
103134052  [KO:K00856] [EC:2.7.1.20]
103134126  pde10a; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X3 [KO:K18438] [EC:3.1.4.17 3.1.4.35]
103134327  pde11a; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A [KO:K13298] [EC:3.1.4.17 3.1.4.35]
103134679  [KO:K03783] [EC:2.4.2.1]
103134683  [KO:K03783] [EC:2.4.2.1]
103134828  [KO:K08045] [EC:4.6.1.1]
103135144  [KO:K00939] [EC:2.7.4.3]
103135158  gmpr; GMP reductase 1 [KO:K00364] [EC:1.7.1.7]
103135166  [KO:K10808] [EC:1.17.4.1]
103135203  [KO:K01513] [EC:3.1.4.1 3.6.1.9]
103135434  [KO:K13293] [EC:3.1.4.53]
103135621  prps1; ribose-phosphate pyrophosphokinase 1 isoform X1 [KO:K00948] [EC:2.7.6.1]
103135697  [KO:K13755] [EC:3.1.4.17]
103135757  guk1; guanylate kinase isoform X1 [KO:K00942] [EC:2.7.4.8]
103135846  [KO:K18437] [EC:3.1.4.53]
103135877  dck; deoxycytidine kinase isoform X1 [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
103135932  [KO:K18437] [EC:3.1.4.53]
103135994  pde1b; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B isoform X1 [KO:K13755] [EC:3.1.4.17]
103136063  [KO:K01081] [EC:3.1.3.5]
103136099  adssl1; adenylosuccinate synthetase isozyme 1 [KO:K01939] [EC:6.3.4.4]
103136188  [KO:K01511] [EC:3.6.1.6]
103136248  pde9a; high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A isoform X1 [KO:K13761] [EC:3.1.4.35]
103136300  [KO:K10807] [EC:1.17.4.1]
103136427  [KO:K13293] [EC:3.1.4.53]
103136574  [KO:K07127] [EC:3.5.2.17]
103136576  [KO:K07127] [EC:3.5.2.17]
103137029  pfas; phosphoribosylformylglycinamidine synthase isoform X1 [KO:K01952] [EC:6.3.5.3]
103137058  itpa; inosine triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
103137100  ppat; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
103137221  pgm1; phosphoglucomutase-1 [KO:K01835] [EC:5.4.2.2]
103137226  [KO:K00939] [EC:2.7.4.3]
103137227  ak4; adenylate kinase 4, mitochondrial [KO:K00939] [EC:2.7.4.3]
103137241  [KO:K13293] [EC:3.1.4.53]
103137467  [KO:K01939] [EC:6.3.4.4]
103137650  [KO:K06928] [EC:3.6.1.15]
103137652  [KO:K06928] [EC:3.6.1.15]
103137799  [KO:K13762] [EC:3.1.4.35]
103137821  gucy1a3; guanylate cyclase soluble subunit alpha-3 [KO:K12318] [EC:4.6.1.2]
103137822  gucy1b3; guanylate cyclase soluble subunit beta-1 isoform X2 [KO:K12319] [EC:4.6.1.2]
103137926  pgm2; phosphoglucomutase-2 [KO:K15779] [EC:5.4.2.2 5.4.2.7]
103137982  [KO:K03783] [EC:2.4.2.1]
103138067  adcy7; adenylate cyclase type 7 isoform X1 [KO:K08047] [EC:4.6.1.1]
103138531  [KO:K00942] [EC:2.7.4.8]
103138590  [KO:K08048] [EC:4.6.1.1]
103138639  nme6; nucleoside diphosphate kinase 6 [KO:K00940] [EC:2.7.4.6]
103138674  pde7b; cAMP-specific 3',5'-cyclic phosphodiesterase 7B isoform X2 [KO:K18436] [EC:3.1.4.53]
103138689  ak9; adenylate kinase 9 isoform X1 [KO:K18533] [EC:2.7.4.3 2.7.4.6]
103138807  ak7; adenylate kinase 7 [KO:K00939] [EC:2.7.4.3]
103138881  cecr1; adenosine deaminase CECR1 [KO:K19572] [EC:3.5.4.4]
103139443  pde3b; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [KO:K13296] [EC:3.1.4.17]
103139470  ampd3; AMP deaminase 3 [KO:K01490] [EC:3.5.4.6]
103139584  nudt2; bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] [KO:K01518] [EC:3.6.1.17]
103139718  pde7a; high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A isoform X1 [KO:K18436] [EC:3.1.4.53]
103139735  urad; putative 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K13485] [EC:4.1.1.97]
103139871  hprt1; hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
103139954  adcy3; adenylate cyclase type 3 isoform X1 [KO:K08043] [EC:4.6.1.1]
103140006  [KO:K13293] [EC:3.1.4.53]
103140008  [KO:K01835] [EC:5.4.2.2]
103140083  pde6a; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha isoform X1 [KO:K08718] [EC:3.1.4.35]
103140936  [KO:K13759]
103140961  cant1; soluble calcium-activated nucleotidase 1 isoform X1 [KO:K12304] [EC:3.6.1.6]
103141004  [KO:K08049] [EC:4.6.1.1]
103141066  [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
103141167  [KO:K08046] [EC:4.6.1.1]
103141208  [KO:K08046] [EC:4.6.1.1]
103141417  enpp4; bis(5'-adenosyl)-triphosphatase ENPP4 [KO:K18424] [EC:3.6.1.29]
103141934  entpd2; ectonucleoside triphosphate diphosphohydrolase 2 [KO:K01509] [EC:3.6.1.-]
103142330  [KO:K00856] [EC:2.7.1.20]
103142511  [KO:K03783] [EC:2.4.2.1]
103142628  [KO:K00940] [EC:2.7.4.6]
103142678  hddc3; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 [KO:K21138] [EC:3.1.7.2]
103142774  [KO:K00939] [EC:2.7.4.3]
103142775  [KO:K00939] [EC:2.7.4.3]
103142776  [KO:K00939] [EC:2.7.4.3]
103142996  [KO:K08041] [EC:4.6.1.1]
103143443  ak2; adenylate kinase 2, mitochondrial isoform X1 [KO:K00939] [EC:2.7.4.3]
103143545  atic; bifunctional purine biosynthesis protein PURH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
103143581  [KO:K18437] [EC:3.1.4.53]
103143662  [KO:K13760]
103143746  [KO:K13293] [EC:3.1.4.53]
103143816  nt5m; 5'(3')-deoxyribonucleotidase, mitochondrial [KO:K01081] [EC:3.1.3.5]
103143832  pde4c; cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X2 [KO:K13293] [EC:3.1.4.53]
103143901  papss1; bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
103144118  [KO:K08043] [EC:4.6.1.1]
103144149  hddc2; HD domain-containing protein 2 [KO:K07023] [EC:3.1.3.89]
103144496  adprm; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
103145114  entpd1; ectonucleoside triphosphate diphosphohydrolase 1 isoform X1 [KO:K01510] [EC:3.6.1.5]
103145373  [KO:K12322] [EC:4.6.1.2]
103145401  nme3; nucleoside diphosphate kinase 3 isoform X1 [KO:K00940] [EC:2.7.4.6]
103145423  [KO:K00940] [EC:2.7.4.6]
103145552  gucy1a2; guanylate cyclase soluble subunit alpha-2 [KO:K12318] [EC:4.6.1.2]
103145576  [KO:K19021] [EC:3.1.4.17]
103145622  [KO:K10807] [EC:1.17.4.1]
103145633  gda; guanine deaminase [KO:K01487] [EC:3.5.4.3]
103145661  entpd4; ectonucleoside triphosphate diphosphohydrolase 4 isoform X1 [KO:K12305] [EC:3.6.1.6]
103145920  [KO:K03783] [EC:2.4.2.1]
103145975  [KO:K00364] [EC:1.7.1.7]
103146018  [KO:K08042] [EC:4.6.1.1]
103146247  [KO:K00088] [EC:1.1.1.205]
103146284  pde2a; cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X2 [KO:K18283] [EC:3.1.4.17]
103146673  [KO:K01081] [EC:3.1.3.5]
103146793  rrm2; ribonucleoside-diphosphate reductase subunit M2 [KO:K10808] [EC:1.17.4.1]
103146804  allc; probable allantoicase [KO:K01477] [EC:3.5.3.4]
103146874  [KO:K00940] [EC:2.7.4.6]
103147386  adsl; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
103147585  [KO:K01490] [EC:3.5.4.6]
103147758  ak3; GTP:AMP phosphotransferase AK3, mitochondrial [KO:K00944] [EC:2.7.4.10]
103147813  [KO:K08046] [EC:4.6.1.1]
103147814  [KO:K08046] [EC:4.6.1.1]
103148141  [KO:K13756] [EC:3.1.4.35]
103148351  [KO:K01081] [EC:3.1.3.5]
103148612  ak5; adenylate kinase isoenzyme 5 [KO:K00939] [EC:2.7.4.3]
103149118  [KO:K12324] [EC:4.6.1.2]
103149367  [KO:K01081] [EC:3.1.3.5]
103149373  [KO:K07127] [EC:3.5.2.17]
103149387  [KO:K12321] [EC:4.6.1.2]
103149765  [KO:K01513] [EC:3.1.4.1 3.6.1.9]
103150368  [KO:K13298] [EC:3.1.4.17 3.1.4.35]
103150496  [KO:K12304] [EC:3.6.1.6]
103150650  pde6g; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma [KO:K13759]
103150682  [KO:K01490] [EC:3.5.4.6]
103150940  [KO:K08048] [EC:4.6.1.1]
103150941  xdh; xanthine dehydrogenase/oxidase [KO:K00106] [EC:1.17.1.4 1.17.3.2]
103151063  [KO:K01490] [EC:3.5.4.6]
103151136  [KO:K13760]
103151138  [KO:K13760]
103151208  pde6c; cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' [KO:K13757] [EC:3.1.4.35]
103151327  [KO:K16855] [EC:3.6.1.62 3.6.1.64]
103151344  nme7; nucleoside diphosphate kinase 7 isoform X3 [KO:K00940] [EC:2.7.4.6]
103151396  pde1a; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X1 [KO:K13755] [EC:3.1.4.17]
103151529  nudt5; ADP-sugar pyrophosphatase [KO:K13987] [EC:3.6.1.13 3.6.1.58 2.7.7.96]
103151564  [KO:K08042] [EC:4.6.1.1]
103151760  [KO:K22600] [EC:4.6.1.2]
103151843  [KO:K00904] [EC:2.7.1.113]
103151924  prps2; ribose-phosphate pyrophosphokinase 2 [KO:K00948] [EC:2.7.6.1]
103152478  ada; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
103152543  [KO:K19021] [EC:3.1.4.17]
103152661  [KO:K01511] [EC:3.6.1.6]
103153337  nudt9; ADP-ribose pyrophosphatase, mitochondrial [KO:K13988] [EC:3.6.1.13]
103153344  [KO:K00940] [EC:2.7.4.6]
103153414  gucy2c; heat-stable enterotoxin receptor isoform X1 [KO:K12320] [EC:4.6.1.2]
103153998  gmps; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
103154140  [KO:K08049] [EC:4.6.1.1]
103154297  aprt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
103154385  [KO:K01509] [EC:3.6.1.-]
103154519  [KO:K12324] [EC:4.6.1.2]
103154685  [KO:K12322] [EC:4.6.1.2]
103155660  impdh2; inosine-5'-monophosphate dehydrogenase 2 isoform X1 [KO:K00088] [EC:1.1.1.205]
103155789  [KO:K01081] [EC:3.1.3.5]
103156017  adcy8; adenylate cyclase type 8 isoform X1 [KO:K08048] [EC:4.6.1.1]
103156214  pde6d; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta isoform X1 [KO:K13758]
103156467  lacc1; laccase domain-containing protein 1 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
103156856  gart; trifunctional purine biosynthetic protein adenosine-3 isoform X2 [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
103156938  [KO:K19572] [EC:3.5.4.4]
107836182  pde6h; retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma [KO:K13759]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
pfor00030  Pentose phosphate pathway
pfor00220  Arginine biosynthesis
pfor00250  Alanine, aspartate and glutamate metabolism
pfor00260  Glycine, serine and threonine metabolism
pfor00340  Histidine metabolism
pfor00630  Glyoxylate and dicarboxylate metabolism
pfor00730  Thiamine metabolism
pfor00740  Riboflavin metabolism
pfor00790  Folate biosynthesis
KO pathway
ko00230   

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