KEGG   PATHWAY: rbb04144
Entry
rbb04144                    Pathway                                
Name
Endocytosis - Rhinopithecus bieti (black snub-nosed monkey)
Description
Endocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins entering through clathrin-dependent endocytosis (CDE) have sequences in their cytoplasmic domains that bind to the APs (adaptor-related protein complexes) and enable their rapid removal from the PM. In addition to APs and clathrin, there are numerous accessory proteins including dynamin. Depending on the various proteins that enter the endosome membrane, these cargoes are sorted to distinct destinations. Some cargoes, such as nutrient receptors, are recycled back to the PM. Ubiquitylated membrane proteins, such as activated growth-factor receptors, are sorted into intraluminal vesicles and eventually end up in the lysosome lumen via multivesicular endosomes (MVEs). There are distinct mechanisms of clathrin-independent endocytosis (CIE) depending upon the cargo and the cell type.
Class
Cellular Processes; Transport and catabolism
Pathway map
rbb04144  Endocytosis
rbb04144

Other DBs
GO: 0006897
Organism
Rhinopithecus bieti (black snub-nosed monkey) [GN:rbb]
Gene
108512110  SH3GL1; endophilin-A2 isoform X1 [KO:K11247]
108512122  [KO:K00889] [EC:2.7.1.68]
108512426  VPS29; vacuolar protein sorting-associated protein 29 isoform X1 [KO:K18467]
108512466  TGFBR1; TGF-beta receptor type-1 isoform X1 [KO:K04674] [EC:2.7.11.30]
108512667  PIP5K1C; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [KO:K00889] [EC:2.7.1.68]
108512721  ARPC5; actin-related protein 2/3 complex subunit 5 [KO:K05754]
108512733  IL2RB; interleukin-2 receptor subunit beta isoform X1 [KO:K05069]
108512773  CYTH4; cytohesin-4 [KO:K18441]
108512778  CHMP2B; charged multivesicular body protein 2b [KO:K12192]
108512814  DNM1; dynamin-1 isoform X1 [KO:K01528] [EC:3.6.5.5]
108512826  SH3GLB2; endophilin-B2 isoform X1 [KO:K21269]
108513001  AP2A2; LOW QUALITY PROTEIN: AP-2 complex subunit alpha-2 [KO:K11824]
108513128  [KO:K18466]
108513135  PRKCI; protein kinase C iota type [KO:K06069] [EC:2.7.11.13]
108513583  RAB11FIP1; rab11 family-interacting protein 1 isoform X1 [KO:K12484]
108513680  ARF6; ADP-ribosylation factor 6 [KO:K07941]
108513853  GRK5; G protein-coupled receptor kinase 5 isoform X1 [KO:K08291] [EC:2.7.11.16]
108514002  ARFGAP3; ADP-ribosylation factor GTPase-activating protein 3 [KO:K12493]
108514337  CHMP2A; charged multivesicular body protein 2a [KO:K12191]
108514342  RABEP1; rab GTPase-binding effector protein 1 isoform X1 [KO:K12480]
108514435  ACAP1; LOW QUALITY PROTEIN: arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 [KO:K12489]
108514499  SH3GLB1; endophilin-B1 [KO:K11248]
108514504  [KO:K12196]
108514714  SMAD3; mothers against decapentaplegic homolog 3 isoform X1 [KO:K23605]
108514718  RAB11A; ras-related protein Rab-11A [KO:K07904]
108514889  RUFY2; RUN and FYVE domain-containing protein 2 isoform X1 [KO:K12482]
108515093  PSD; PH and SEC7 domain-containing protein 1 [KO:K12494]
108515098  GBF1; Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 isoform X1 [KO:K18443]
108515270  CAPZB; F-actin-capping protein subunit beta isoform X1 [KO:K10365]
108515312  RAB22A; ras-related protein Rab-22A [KO:K07891]
108515376  PARD6A; partitioning defective 6 homolog alpha isoform X1 [KO:K06093]
108515670  CBLC; E3 ubiquitin-protein ligase CBL-C [KO:K22518] [EC:2.3.2.27]
108515926  KIF5B; LOW QUALITY PROTEIN: kinesin-1 heavy chain [KO:K10396] [EC:5.6.1.3]
108515962  GRK3; LOW QUALITY PROTEIN: beta-adrenergic receptor kinase 2 [KO:K00910] [EC:2.7.11.15]
108515978  DAB2; LOW QUALITY PROTEIN: disabled homolog 2 [KO:K12475]
108516011  RNF41; E3 ubiquitin-protein ligase NRDP1 isoform X1 [KO:K11981] [EC:2.3.2.27]
108516054  RAB5B; ras-related protein Rab-5B [KO:K07888]
108516180  IGF2R; cation-independent mannose-6-phosphate receptor isoform X1 [KO:K06564]
108516246  ASAP2; arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 isoform X1 [KO:K12488]
108516417  RAB31; ras-related protein Rab-31 [KO:K07891]
108516480  SNF8; vacuolar-sorting protein SNF8 isoform X1 [KO:K12188]
108516506  EPN3; epsin-3 isoform X1 [KO:K12471]
108516558  TGFBR2; TGF-beta receptor type-2 [KO:K04388] [EC:2.7.11.30]
108516584  SPG20; spartin [KO:K19366]
108516629  EHD3; EH domain-containing protein 3 isoform X1 [KO:K12476]
108516764  EPN2; epsin-2 isoform X1 [KO:K12471]
108516960  [KO:K18584]
108517295  GIT1; ARF GTPase-activating protein GIT1 isoform X1 [KO:K05737]
108517364  VPS37D; vacuolar protein sorting-associated protein 37D [KO:K12185]
108517436  SNX4; LOW QUALITY PROTEIN: sorting nexin-4 [KO:K17919]
108517666  CCR5; C-C chemokine receptor type 5 [KO:K04180]
108518034  LDLRAP1; LOW QUALITY PROTEIN: low density lipoprotein receptor adapter protein 1 [KO:K12474]
108518346  RAB5C; ras-related protein Rab-5C [KO:K07889]
108518391  CLTCL1; clathrin heavy chain 2 isoform X1 [KO:K04646]
108518515  WIPF1; LOW QUALITY PROTEIN: WAS/WASL-interacting protein family member 1 [KO:K19475]
108518610  GRK2; beta-adrenergic receptor kinase 1 isoform X1 [KO:K00910] [EC:2.7.11.15]
108518633  SNX32; sorting nexin-32 isoform X1 [KO:K17920]
108519244  TSG101; LOW QUALITY PROTEIN: tumor susceptibility gene 101 protein [KO:K12183]
108519603  SMAD2; mothers against decapentaplegic homolog 2 isoform X1 [KO:K04500]
108519708  KIF5A; kinesin heavy chain [KO:K10396] [EC:5.6.1.3]
108519736  CHMP4C; charged multivesicular body protein 4c [KO:K24782]
108519844  SRC; proto-oncogene tyrosine-protein kinase Src isoform X1 [KO:K05704] [EC:2.7.10.2]
108519908  RBSN; rabenosyn-5 [KO:K12481]
108520227  [KO:K03283]
108520228  [KO:K03283]
108520300  IQSEC2; IQ motif and SEC7 domain-containing protein 2 isoform X1 [KO:K12495]
108520383  SNX2; LOW QUALITY PROTEIN: sorting nexin-2 [KO:K17917]
108520727  ARRB2; beta-arrestin-2 isoform X1 [KO:K04439]
108520763  ACTR3B; actin-related protein 3B [KO:K18584]
108521127  RAB11FIP3; rab11 family-interacting protein 3 isoform X1 [KO:K12485]
108521254  RAB5A; ras-related protein Rab-5A [KO:K07887]
108521497  WIPF3; LOW QUALITY PROTEIN: WAS/WASL-interacting protein family member 3 [KO:K19475]
108521833  GRK1; rhodopsin kinase [KO:K00909] [EC:2.7.11.14]
108521866  STAMBP; STAM-binding protein isoform X1 [KO:K11866] [EC:3.4.19.12]
108521958  ARFGAP2; ADP-ribosylation factor GTPase-activating protein 2 isoform X1 [KO:K12493]
108522039  EGFR; epidermal growth factor receptor isoform X1 [KO:K04361] [EC:2.7.10.1]
108522348  GRK7; rhodopsin kinase [KO:K00909] [EC:2.7.11.14]
108522524  ARFGEF2; brefeldin A-inhibited guanine nucleotide-exchange protein 2 isoform X1 [KO:K18442]
108522562  [KO:K06751]
108522670  [KO:K17920]
108522739  GRK4; LOW QUALITY PROTEIN: G protein-coupled receptor kinase 4 [KO:K08291] [EC:2.7.11.16]
108522812  [KO:K23484]
108522813  DNM2; dynamin-2 isoform X1 [KO:K23484]
108522983  PARD6G; partitioning defective 6 homolog gamma [KO:K06093]
108523020  [KO:K12491]
108523118  CYTH2; cytohesin-2 isoform X1 [KO:K18441]
108523244  WASL; LOW QUALITY PROTEIN: neural Wiskott-Aldrich syndrome protein [KO:K23612]
108523296  CHMP3; charged multivesicular body protein 3 [KO:K12193]
108523393  TFRC; transferrin receptor protein 1 isoform X1 [KO:K06503]
108523576  SMURF1; E3 ubiquitin-protein ligase SMURF1 [KO:K04678] [EC:2.3.2.26]
108523680  [KO:K05757]
108523846  WASH1; LOW QUALITY PROTEIN: WAS protein family homolog 1 [KO:K18461]
108523850  IQSEC3; LOW QUALITY PROTEIN: IQ motif and SEC7 domain-containing protein 3 [KO:K12495]
108523991  CYTH3; cytohesin-3 [KO:K18441]
108524152  PML; protein PML isoform X1 [KO:K10054] [EC:2.3.2.-]
108524240  VPS36; vacuolar protein-sorting-associated protein 36 isoform X1 [KO:K12190]
108524394  AGAP2; LOW QUALITY PROTEIN: arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 [KO:K17848]
108524653  SNX12; LOW QUALITY PROTEIN: sorting nexin-12 [KO:K17918]
108524783  IQSEC1; IQ motif and SEC7 domain-containing protein 1 isoform X1 [KO:K12495]
108524801  PLD2; phospholipase D2 [KO:K01115] [EC:3.1.4.4]
108524852  AP2M1; AP-2 complex subunit mu isoform X1 [KO:K11826]
108524861  [KO:K12491]
108525019  STAM2; LOW QUALITY PROTEIN: signal transducing adapter molecule 2 [KO:K04705]
108525667  [KO:K06751]
108526025  [KO:K17918]
108526256  DNM3; dynamin-3 isoform X1 [KO:K01528] [EC:3.6.5.5]
108526371  VPS4B; vacuolar protein sorting-associated protein 4B [KO:K12196]
108526459  VPS37A; vacuolar protein sorting-associated protein 37A isoform X1 [KO:K12185]
108526478  PSD3; PH and SEC7 domain-containing protein 3 isoform X1 [KO:K12494]
108526530  CAPZA2; F-actin-capping protein subunit alpha-2 isoform X1 [KO:K10364]
108526568  AMPH; amphiphysin isoform X1 [KO:K12562]
108526768  VPS25; vacuolar protein-sorting-associated protein 25 [KO:K12189]
108526989  RHOA; transforming protein RhoA [KO:K04513]
108527188  EEA1; LOW QUALITY PROTEIN: early endosome antigen 1 [KO:K12478]
108527486  CHMP1B; charged multivesicular body protein 1b [KO:K12197]
108527750  STAM; signal transducing adapter molecule 1 isoform X1 [KO:K04705]
108527932  LDLR; low-density lipoprotein receptor [KO:K12473]
108528096  CAPZA1; F-actin-capping protein subunit alpha-1 [KO:K10364]
108528429  [KO:K06751]
108528432  [KO:K06751]
108528436  [KO:K06751]
108528599  CBL; E3 ubiquitin-protein ligase CBL [KO:K04707] [EC:2.3.2.27]
108528634  ASAP1; LOW QUALITY PROTEIN: arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 [KO:K12488]
108528700  CAV1; caveolin-1 isoform X1 [KO:K06278]
108528701  CAV2; caveolin-2 isoform X1 [KO:K12958]
108528785  VPS37C; LOW QUALITY PROTEIN: vacuolar protein sorting-associated protein 37C [KO:K12185]
108528791  [KO:K03283]
108528889  ZFYVE16; zinc finger FYVE domain-containing protein 16 [KO:K04679]
108529155  RAB11FIP2; rab11 family-interacting protein 2 [KO:K12484]
108529166  IST1; IST1 homolog isoform X1 [KO:K19476]
108529181  SMAP1; stromal membrane-associated protein 1 [KO:K12486]
108529182  CHMP1A; charged multivesicular body protein 1a [KO:K12197]
108529253  PARD3; partitioning defective 3 homolog isoform X1 [KO:K04237]
108529365  [KO:K07937]
108529669  VPS26B; vacuolar protein sorting-associated protein 26B [KO:K18466]
108529768  FGFR2; fibroblast growth factor receptor 2 isoform X1 [KO:K05093] [EC:2.7.10.1]
108529907  IL2RA; interleukin-2 receptor subunit alpha isoform X1 [KO:K05068]
108530209  ARAP3; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1 [KO:K12490]
108530266  PIP5K1B; phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1 [KO:K00889] [EC:2.7.1.68]
108530360  [KO:K05756]
108530400  SMAP2; stromal membrane-associated protein 2 isoform X1 [KO:K12486]
108530511  ACAP2; LOW QUALITY PROTEIN: arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 [KO:K12489]
108530678  SH3GL3; endophilin-A3 [KO:K11247]
108530781  ARF5; ADP-ribosylation factor 5 [KO:K07940]
108530846  PSD2; PH and SEC7 domain-containing protein 2 isoform X1 [KO:K12494]
108530950  CAV3; caveolin-3 [KO:K12959]
108531062  AP2S1; AP-2 complex subunit sigma isoform X1 [KO:K11827]
108531192  ZFYVE9; zinc finger FYVE domain-containing protein 9 [KO:K04679]
108531347  MVB12B; multivesicular body subunit 12B isoform X1 [KO:K12186]
108531367  ARPC5L; actin-related protein 2/3 complex subunit 5-like protein [KO:K05754]
108531507  VPS26A; vacuolar protein sorting-associated protein 26A [KO:K18466]
108531641  WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X1 [KO:K05633] [EC:2.3.2.26]
108531803  EPS15; epidermal growth factor receptor substrate 15 isoform X1 [KO:K12472]
108531954  HSPA8; LOW QUALITY PROTEIN: heat shock cognate 71 kDa protein [KO:K03283]
108532108  IL2RG; cytokine receptor common subunit gamma isoform X1 [KO:K05070]
108532254  MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1 [KO:K06643] [EC:2.3.2.27]
108532286  FGFR3; LOW QUALITY PROTEIN: fibroblast growth factor receptor 3 [KO:K05094] [EC:2.7.10.1]
108532534  AGAP3; arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform X1 [KO:K12491]
108532544  RAB11FIP5; rab11 family-interacting protein 5 isoform X1 [KO:K12484]
108532677  RAB10; ras-related protein Rab-10 isoform X1 [KO:K07903]
108532883  DNAJC6; putative tyrosine-protein phosphatase auxilin [KO:K09526]
108532998  BIN1; myc box-dependent-interacting protein 1 isoform X1 [KO:K12562]
108533052  CLTC; clathrin heavy chain 1 isoform X1 [KO:K04646]
108533237  PIP5K1A; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1 [KO:K00889] [EC:2.7.1.68]
108533279  VPS45; vacuolar protein sorting-associated protein 45 isoform X1 [KO:K12479]
108533621  CHMP4B; charged multivesicular body protein 4b [KO:K12194]
108533724  ITCH; E3 ubiquitin-protein ligase Itchy homolog isoform X1 [KO:K05632] [EC:2.3.2.26]
108533750  PDGFRA; platelet-derived growth factor receptor alpha isoform X1 [KO:K04363] [EC:2.7.10.1]
108533816  SNX3; sorting nexin-3 [KO:K17918]
108534013  RAB35; ras-related protein Rab-35 [KO:K07876]
108534025  KIF5C; kinesin heavy chain [KO:K10396] [EC:5.6.1.3]
108534113  HGS; hepatocyte growth factor-regulated tyrosine kinase substrate isoform X1 [KO:K12182]
108534138  CHMP6; charged multivesicular body protein 6 [KO:K12195]
108534177  CYTH1; cytohesin-1 isoform X1 [KO:K18441]
108534283  MVB12A; LOW QUALITY PROTEIN: multivesicular body subunit 12A [KO:K12186]
108534367  GIT2; ARF GTPase-activating protein GIT2 isoform X1 [KO:K12487]
108534720  WIPF2; LOW QUALITY PROTEIN: WAS/WASL-interacting protein family member 2 [KO:K19475]
108534759  ZFYVE27; protrudin isoform X1 [KO:K19368]
108534773  VPS35; LOW QUALITY PROTEIN: vacuolar protein sorting-associated protein 35 [KO:K18468]
108534812  ARPC4; actin-related protein 2/3 complex subunit 4 [KO:K05755]
108535252  ARFGAP1; ADP-ribosylation factor GTPase-activating protein 1 [KO:K12492]
108535312  NEDD4; E3 ubiquitin-protein ligase NEDD4 [KO:K10591] [EC:2.3.2.26]
108535559  TRAF6; TNF receptor-associated factor 6 isoform X1 [KO:K03175] [EC:2.3.2.27]
108535818  AP2A1; AP-2 complex subunit alpha-1 isoform X1 [KO:K11824]
108535938  [KO:K06643] [EC:2.3.2.27]
108536030  PRKCZ; protein kinase C zeta type isoform X1 [KO:K18952] [EC:2.7.11.13]
108536248  SMURF2; E3 ubiquitin-protein ligase SMURF2 [KO:K04678] [EC:2.3.2.26]
108536605  VPS28; vacuolar protein sorting-associated protein 28 homolog [KO:K12184]
108536648  [KO:K12486]
108536791  ARF1; ADP-ribosylation factor 1 [KO:K07937]
108537392  CHMP5; charged multivesicular body protein 5 [KO:K12198]
108537490  SNX1; sorting nexin-1 isoform X1 [KO:K17917]
108537507  RAB7A; ras-related protein Rab-7a [KO:K07897]
108537546  SPG21; maspardin [KO:K19367]
108537632  ARRB1; beta-arrestin-1 isoform X1 [KO:K04439]
108537852  RAB4A; ras-related protein Rab-4A isoform X1 [KO:K07879]
108537965  CHMP7; charged multivesicular body protein 7 [KO:K15053]
108538082  KIAA0196; WASH complex subunit strumpellin [KO:K18464]
108538447  ASAP3; arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 [KO:K12488]
108538451  CDC42; cell division control protein 42 homolog isoform X1 [KO:K04393]
108538516  [KO:K12199]
108538668  IGF1R; insulin-like growth factor 1 receptor isoform X1 [KO:K05087] [EC:2.7.10.1]
108538908  [KO:K12470]
108539465  RUFY1; RUN and FYVE domain-containing protein 1 isoform X1 [KO:K12482]
108539474  PARD6B; partitioning defective 6 homolog beta [KO:K06093]
108539652  CXCR4; C-X-C chemokine receptor type 4 [KO:K04189]
108539744  CAPZA3; F-actin-capping protein subunit alpha-3 [KO:K10364]
108540246  EHD2; EH domain-containing protein 2 [KO:K12469]
108540404  PLD1; phospholipase D1 [KO:K01115] [EC:3.1.4.4]
108540803  ACTR2; actin-related protein 2 isoform X1 [KO:K17260]
108540853  SH3GL2; endophilin-A1 [KO:K11247]
108540920  VPS37B; vacuolar protein sorting-associated protein 37B isoform X1 [KO:K12185]
108540933  CHMP4A; LOW QUALITY PROTEIN: charged multivesicular body protein 4a [KO:K12194]
108540973  AGAP1; arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 isoform X1 [KO:K12491]
108541057  NEDD4L; E3 ubiquitin-protein ligase NEDD4-like isoform X1 [KO:K13305] [EC:2.3.2.26]
108541402  RAB11FIP4; rab11 family-interacting protein 4 isoform X1 [KO:K12485]
108541450  AP2B1; AP-2 complex subunit beta isoform X1 [KO:K11825]
108541578  ARAP2; LOW QUALITY PROTEIN: arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 [KO:K18440]
108541816  PSD4; PH and SEC7 domain-containing protein 4 isoform X1 [KO:K12494]
108541844  ARPC2; actin-related protein 2/3 complex subunit 2 [KO:K05758]
108541855  CXCR2; C-X-C chemokine receptor type 2 [KO:K05050]
108541896  [KO:K12491]
108542516  EPN1; epsin-1 isoform X1 [KO:K12471]
108542567  CLTA; clathrin light chain A isoform X1 [KO:K04644]
108542584  HSPA6; LOW QUALITY PROTEIN: heat shock 70 kDa protein 6 [KO:K03283]
108542739  PIP5KL1; phosphatidylinositol 4-phosphate 5-kinase-like protein 1 [KO:K13712] [EC:2.7.1.68]
108542766  PDCD6IP; programmed cell death 6-interacting protein isoform X1 [KO:K12200]
108542981  EHD1; EH domain-containing protein 1 isoform X1 [KO:K12483]
108543093  [KO:K06751]
108543097  [KO:K06751]
108543136  CCDC53; WASH complex subunit CCDC53 isoform X1 [KO:K18463]
108543281  RAB8A; ras-related protein Rab-8A [KO:K07901]
108543284  EPS15L1; epidermal growth factor receptor substrate 15-like 1 isoform X1 [KO:K12472]
108543525  HRAS; GTPase HRas isoform X1 [KO:K02833]
108543593  ARF4; ADP-ribosylation factor 4 [KO:K07939]
108543763  ARAP1; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 isoform X1 [KO:K18439]
108543774  FOLR2; folate receptor beta [KO:K13649]
108543775  FOLR1; folate receptor alpha [KO:K13649]
108543777  [KO:K13649]
108543926  ARF3; ADP-ribosylation factor 3 [KO:K07938]
108544204  ACAP3; arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 [KO:K12489]
108544248  KIAA1033; LOW QUALITY PROTEIN: WASH complex subunit 7 [KO:K18465]
108544347  EHD4; EH domain-containing protein 4 [KO:K12477]
108544411  SNX5; sorting nexin-5 [KO:K17920]
108544485  CBLB; E3 ubiquitin-protein ligase CBL-B isoform X1 [KO:K22517] [EC:2.3.2.27]
108544682  ARPC3; actin-related protein 2/3 complex subunit 3 [KO:K05756]
108544759  FGFR4; LOW QUALITY PROTEIN: fibroblast growth factor receptor 4 [KO:K05095] [EC:2.7.10.1]
108544772  GRK6; G protein-coupled receptor kinase 6 isoform X1 [KO:K08291] [EC:2.7.11.16]
108544804  CLTB; clathrin light chain B isoform X1 [KO:K04645]
108544834  USP8; LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 8 [KO:K11839] [EC:3.4.19.12]
108544897  ARFGEF1; LOW QUALITY PROTEIN: brefeldin A-inhibited guanine nucleotide-exchange protein 1 [KO:K18442]
108545006  VTA1; LOW QUALITY PROTEIN: vacuolar protein sorting-associated protein VTA1 homolog [KO:K12199]
Compound
C00035  GDP
C00044  GTP
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
Reference
PMID:19007773
  Authors
Acconcia F, Sigismund S, Polo S
  Title
Ubiquitin in trafficking: the network at work.
  Journal
Exp Cell Res 315:1610-8 (2009)
DOI:10.1016/j.yexcr.2008.10.014
Reference
PMID:18647649
  Authors
Donaldson JG, Porat-Shliom N, Cohen LA
  Title
Clathrin-independent endocytosis: a unique platform for cell signaling and PM remodeling.
  Journal
Cell Signal 21:1-6 (2009)
DOI:10.1016/j.cellsig.2008.06.020
Reference
PMID:15261671
  Authors
Sorkin A
  Title
Cargo recognition during clathrin-mediated endocytosis: a team effort.
  Journal
Curr Opin Cell Biol 16:392-9 (2004)
DOI:10.1016/j.ceb.2004.06.001
Reference
PMID:19325624
  Authors
Raiborg C, Stenmark H
  Title
The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins.
  Journal
Nature 458:445-52 (2009)
DOI:10.1038/nature07961
Reference
PMID:20110990
  Authors
Scita G, Di Fiore PP
  Title
The endocytic matrix.
  Journal
Nature 463:464-73 (2010)
DOI:10.1038/nature08910
Reference
PMID:15687999
  Authors
Le Roy C, Wrana JL
  Title
Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling.
  Journal
Nat Rev Mol Cell Biol 6:112-26 (2005)
DOI:10.1038/nrm1571
Reference
PMID:19924646
  Authors
Jovic M, Sharma M, Rahajeng J, Caplan S
  Title
The early endosome: a busy sorting station for proteins at the crossroads.
  Journal
Histol Histopathol 25:99-112 (2010)
DOI:10.14670/HH-25.99
Reference
PMID:16203612
  Authors
Pietiainen VM, Marjomaki V, Heino J, Hyypia T
  Title
Viral entry, lipid rafts and caveosomes.
  Journal
Ann Med 37:394-403 (2005)
DOI:10.1080/07853890510011976
Reference
PMID:19696797
  Authors
Grant BD, Donaldson JG
  Title
Pathways and mechanisms of endocytic recycling.
  Journal
Nat Rev Mol Cell Biol 10:597-608 (2009)
DOI:10.1038/nrm2755
Reference
PMID:22193161
  Authors
Cullen PJ, Korswagen HC
  Title
Sorting nexins provide diversity for retromer-dependent trafficking events.
  Journal
Nat Cell Biol 14:29-37 (2012)
DOI:10.1038/ncb2374
Related
pathway
rbb04060  Cytokine-cytokine receptor interaction
rbb04070  Phosphatidylinositol signaling system
rbb04130  SNARE interactions in vesicular transport
rbb04142  Lysosome
rbb04350  TGF-beta signaling pathway
KO pathway
ko04144   

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