KEGG   COMPOUND: C00065
Entry
C00065                      Compound                               
Name
L-Serine;
L-2-Amino-3-hydroxypropionic acid;
L-3-Hydroxy-alanine;
Serine
Formula
C3H7NO3
Exact mass
105.0426
Mol weight
105.09
Structure
Remark
Same as: D00016
Reaction
R00220 R00581 R00582 R00584 R00585 R00586 R00588 R00589
R00590 R00674 R00891 R00945 R01281 R01289 R01290 R01800
R02378 R02563 R02722 R02817 R03662 R03923 R04942 R06126
R07376 R07377 R07644 R08218 R09099 R10255 R10441 R10880
R10984 R10985 R10986 R11667 R12342 R12344 R12757 R12779
R12781 R13249
Pathway
map00260  Glycine, serine and threonine metabolism
map00261  Monobactam biosynthesis
map00270  Cysteine and methionine metabolism
map00460  Cyanoamino acid metabolism
map00470  D-Amino acid metabolism
map00564  Glycerophospholipid metabolism
map00600  Sphingolipid metabolism
map00630  Glyoxylate and dicarboxylate metabolism
map00670  One carbon pool by folate
map00680  Methane metabolism
map00920  Sulfur metabolism
map00970  Aminoacyl-tRNA biosynthesis
map00997  Biosynthesis of various other secondary metabolites
map00998  Biosynthesis of various antibiotics
map01054  Nonribosomal peptide structures
map01060  Biosynthesis of plant secondary metabolites
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
map01200  Carbon metabolism
map01230  Biosynthesis of amino acids
map01240  Biosynthesis of cofactors
map01502  Vancomycin resistance
map02010  ABC transporters
map04071  Sphingolipid signaling pathway
map04974  Protein digestion and absorption
map04978  Mineral absorption
map05230  Central carbon metabolism in cancer
Module
M00020  Serine biosynthesis, glycerate-3P => serine
M00021  Cysteine biosynthesis, serine => cysteine
M00035  Methionine degradation
M00094  Ceramide biosynthesis
M00338  Cysteine biosynthesis, homocysteine + serine => cysteine
M00346  Formaldehyde assimilation, serine pathway
M00532  Photorespiration
M00736  Nocardicin A biosynthesis, L-pHPG + arginine + serine => nocardicin A
M00785  Cycloserine biosynthesis, arginine/serine => cycloserine
M00875  Staphyloferrin B biosynthesis, L-serine => staphyloferrin B
M00975  Betaine degradation, bacteria, betaine => pyruvate
Network
nt06030  Methionine metabolism
nt06033  Glycine, serine and arginine metabolism
nt06038  Folate metabolism
nt06545  Cornified envelope formation
Enzyme
1.1.1.276       1.1.1.387       1.4.1.7         2.1.2.1         
2.3.1.30        2.3.1.50        2.6.1.45        2.6.1.51        
2.7.1.80        2.7.1.225       2.7.1.226       2.7.8.4         
2.7.8.8         2.7.8.29        2.7.8.38        2.8.1.4         
3.1.3.3         3.1.4.13        4.1.1.-         4.2.1.20        
4.2.1.22        4.2.1.50        4.2.1.122       4.3.1.17        
4.3.1.19        5.1.1.10        5.1.1.18        6.1.1.11        
6.2.1.72        6.3.2.14
Brite
Compounds with biological roles [BR:br08001]
 Peptides
  Amino acids
   Common amino acids
    C00065  Serine (Ser)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00016  L-Serine
Other DBs
CAS: 56-45-1
PubChem: 3365
ChEBI: 17115
KNApSAcK: C00001393
PDB-CCD: SER[PDBj]
NIKKAJI: J1.195I
LinkDB
KCF data

ATOM        7
            1   C1c C    23.5961  -17.5357
            2   C6a C    22.4445  -16.7873
            3   C1b C    24.8238  -16.8518
            4   N1a N    23.6370  -18.9388
            5   O6a O    21.2226  -17.4714
            6   O6a O    22.4677  -15.3785
            7   O1a O    26.0339  -17.5708
BOND        6
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Down
            4     2   5 1
            5     2   6 2
            6     3   7 1

» Japanese version

KEGG   COMPOUND: C00101
Entry
C00101                      Compound                               
Name
Tetrahydrofolate;
5,6,7,8-Tetrahydrofolate;
Tetrahydrofolic acid;
THF;
(6S)-Tetrahydrofolate;
(6S)-Tetrahydrofolic acid;
(6S)-THFA
Formula
C19H23N7O6
Exact mass
445.1710
Mol weight
445.43
Structure
Reaction
R00611 R00936 R00937 R00939 R00940 R00941 R00942 R00943
R00944 R00945 R00946 R01221 R01225 R01226 R01564 R01565
R01669 R02287 R02289 R02573 R02729 R02912 R03189 R03704
R03940 R04125 R04242 R04325 R04326 R04560 R06613 R07660
R08701 R09093 R09270 R09271 R10136 R10243 R10333 R11955
R11956 R12548 R12790 R12967
Pathway
map00260  Glycine, serine and threonine metabolism
map00670  One carbon pool by folate
map00680  Methane metabolism
map00720  Other carbon fixation pathways
map00785  Lipoic acid metabolism
map00790  Folate biosynthesis
map00970  Aminoacyl-tRNA biosynthesis
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01200  Carbon metabolism
map01240  Biosynthesis of cofactors
map01523  Antifolate resistance
map04980  Cobalamin transport and metabolism
map04981  Folate transport and metabolism
Module
M00126  Tetrahydrofolate biosynthesis, GTP => THF
M00140  C1-unit interconversion, prokaryotes
M00141  C1-unit interconversion, eukaryotes
M00377  Reductive acetyl-CoA pathway (Wood-Ljungdahl pathway)
M00621  Glycine cleavage system
M00840  Tetrahydrofolate biosynthesis, mediated by ribA and trpF, GTP => THF
M00841  Tetrahydrofolate biosynthesis, mediated by PTPS, GTP => THF
Network
nt06030  Methionine metabolism
nt06033  Glycine, serine and arginine metabolism
nt06038  Folate metabolism
Enzyme
1.4.1.27        1.5.1.3         1.5.1.6         1.5.3.10        
1.5.3.24        1.5.8.3         1.5.8.4         2.1.1.13        
2.1.1.19        2.1.1.74        2.1.1.148       2.1.1.258       
2.1.1.269       2.1.1.341       2.1.1.378       2.1.1.385       
2.1.1.389       2.1.1.-         2.1.2.1         2.1.2.2         
2.1.2.3         2.1.2.4         2.1.2.5         2.1.2.7         
2.1.2.8         2.1.2.9         2.1.2.10        2.1.2.11        
2.1.2.13        2.1.2.14        2.1.5.1         2.3.1.169       
3.4.19.9        3.5.1.10        6.3.2.17        6.3.4.3
Brite
Compounds with biological roles [BR:br08001]
 Vitamins and cofactors
  Cofactors
   Coenzymes
    C00101  THF
Other DBs
CAS: 135-16-0
PubChem: 3401
ChEBI: 15635 20506
KNApSAcK: C00007249
PDB-CCD: THG[PDBj]
NIKKAJI: J184.393A
LinkDB
KCF data

ATOM        32
            1   N4x N     9.5392  -17.5978
            2   C8y C     9.5392  -19.0001
            3   N5x N    10.7312  -19.7013
            4   C8y C    11.9933  -19.0001
            5   C8y C    11.9933  -17.5978
            6   C8y C    10.7312  -16.8966
            7   N1x N    13.1853  -19.7013
            8   C1x C    14.3773  -19.0001
            9   C1y C    14.3773  -17.5978
            10  N1x N    13.1853  -16.8966
            11  O5x O    10.7312  -15.4943
            12  N1a N     8.3219  -19.6964
            13  C1b C    15.5918  -16.8966
            14  N1b N    16.8063  -17.5978
            15  C8y C    18.0207  -16.8966
            16  C8x C    19.2373  -17.5990
            17  C8x C    20.4517  -16.8978
            18  C8y C    20.4517  -15.4955
            19  C8x C    19.2352  -14.7931
            20  C8x C    18.0207  -15.4943
            21  C5a C    21.6920  -14.7931
            22  N1b N    22.9065  -15.4943
            23  O5a O    21.6979  -13.3911
            24  C1c C    24.1397  -14.7821
            25  C1b C    25.3469  -15.4790
            26  C1b C    26.5312  -14.7950
            27  C6a C    27.7272  -15.4855
            28  O6a O    28.9171  -14.7983
            29  O6a O    27.7274  -16.8963
            30  C6a C    24.1394  -13.3909
            31  O6a O    22.9130  -12.6830
            32  O6a O    25.3419  -12.6962
BOND        34
            1     1   2 1
            2     2   3 2
            3     3   4 1
            4     4   5 2
            5     5   6 1
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12    6  11 2
            13    2  12 1
            14    9  13 1 #Up
            15   13  14 1
            16   14  15 1
            17   15  16 2
            18   16  17 1
            19   17  18 2
            20   18  19 1
            21   19  20 2
            22   15  20 1
            23   18  21 1
            24   21  22 1
            25   21  23 2
            26   22  24 1
            27   24  25 1
            28   25  26 1
            29   26  27 1
            30   27  28 1
            31   27  29 2
            32   24  30 1 #Down
            33   30  31 2
            34   30  32 1

» Japanese version

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