KEGG   ORTHOLOGY: K18497
Entry
K18497                      KO                                     
Symbol
FGF2
Name
fibroblast growth factor 2
Pathway
map01521  EGFR tyrosine kinase inhibitor resistance
map04010  MAPK signaling pathway
map04014  Ras signaling pathway
map04015  Rap1 signaling pathway
map04020  Calcium signaling pathway
map04151  PI3K-Akt signaling pathway
map04550  Signaling pathways regulating pluripotency of stem cells
map04810  Regulation of actin cytoskeleton
map05167  Kaposi sarcoma-associated herpesvirus infection
map05200  Pathways in cancer
map05205  Proteoglycans in cancer
map05207  Chemical carcinogenesis - receptor activation
map05218  Melanoma
map05224  Breast cancer
map05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K18497  FGF2; fibroblast growth factor 2
   04014 Ras signaling pathway
    K18497  FGF2; fibroblast growth factor 2
   04015 Rap1 signaling pathway
    K18497  FGF2; fibroblast growth factor 2
   04020 Calcium signaling pathway
    K18497  FGF2; fibroblast growth factor 2
   04151 PI3K-Akt signaling pathway
    K18497  FGF2; fibroblast growth factor 2
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K18497  FGF2; fibroblast growth factor 2
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K18497  FGF2; fibroblast growth factor 2
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K18497  FGF2; fibroblast growth factor 2
   05205 Proteoglycans in cancer
    K18497  FGF2; fibroblast growth factor 2
   05207 Chemical carcinogenesis - receptor activation
    K18497  FGF2; fibroblast growth factor 2
  09162 Cancer: specific types
   05226 Gastric cancer
    K18497  FGF2; fibroblast growth factor 2
   05218 Melanoma
    K18497  FGF2; fibroblast growth factor 2
   05224 Breast cancer
    K18497  FGF2; fibroblast growth factor 2
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    K18497  FGF2; fibroblast growth factor 2
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    K18497  FGF2; fibroblast growth factor 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K18497  FGF2; fibroblast growth factor 2
   00536 Glycosaminoglycan binding proteins
    K18497  FGF2; fibroblast growth factor 2
Cytokines and growth factors [BR:ko04052]
 Growth factors
  Growth factors (RTK binding)
   K18497  FGF2; fibroblast growth factor 2
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   K18497  FGF2; fibroblast growth factor 2
Other DBs
GO: 0005104
Genes
HSA: 2247(FGF2)
PTR: 641462(FGF2)
PPS: 100968351(FGF2)
GGO: 101137337(FGF2)
PON: 100459751(FGF2)
NLE: 100593123(FGF2)
MCC: 574136(FGF2)
MCF: 102133679(FGF2)
CSAB: 103236710(FGF2)
CATY: 105595795(FGF2)
PANU: 101003965(FGF2)
TGE: 112624619(FGF2)
RRO: 104661758(FGF2)
RBB: 108515579(FGF2)
TFN: 117085877(FGF2)
PTEH: 111546245(FGF2)
SBQ: 101030554(FGF2)
MMUR: 105882072(FGF2)
OGA: 100942631(FGF2)
MMU: 14173(Fgf2)
MCAL: 110291557(Fgf2)
MPAH: 110320512(Fgf2)
RNO: 54250(Fgf2)
MCOC: 116095116(Fgf2)
MUN: 110545886(Fgf2)
CGE: 100757429(Fgf2)
PLEU: 114707170(Fgf2)
NGI: 103746947(Fgf2)
HGL: 101720583(Fgf2)
CPOC: 100721182(Fgf2)
DORD: 105989908(Fgf2)
DSP: 122119078(Fgf2)
OCU: 100009068(FGF2)
OPI: 101520285(FGF2)
TUP: 102498637(FGF2)
CFA: 403857(FGF2)
VVP: 112933647(FGF2)
VLG: 121493095(FGF2)
AML: 100479986(FGF2)
UMR: 103661850(FGF2)
UAH: 113255677(FGF2)
UAR: 123793143(FGF2)
ELK: 111156005
MPUF: 101671799(FGF2)
ORO: 101369428(FGF2)
EJU: 114208195(FGF2)
ZCA: 113925505(FGF2)
MLX: 118022565(FGF2)
FCA: 100135772(FGF2)
PYU: 121030066(FGF2)
PBG: 122469044(FGF2)
PTG: 102969772(FGF2)
PPAD: 109246691(FGF2)
AJU: 106977090(FGF2)
HHV: 120238033(FGF2)
BTA: 281161(FGF2)
BOM: 102284897(FGF2)
BIU: 109570879(FGF2)
BBUB: 102393273(FGF2)
CHX: 102186892(FGF2)
OAS: 443306(FGF2)
ODA: 120871375(FGF2)
CCAD: 122453183(FGF2)
SSC: 397643(FGF2)
CBAI: 105067112(FGF2)
CDK: 105093669(FGF2)
BACU: 103015722(FGF2)
LVE: 103090898(FGF2)
OOR: 101280803(FGF2)
DLE: 111186075(FGF2)
PCAD: 102989017(FGF2)
PSIU: 116753904(FGF2) 116758288
ECB: 100033955(FGF2)
MYB: 102246008(FGF2)
MYD: 102762815(FGF2)
MMYO: 118657980(FGF2)
MLF: 111825710(FGF2)
MNA: 107529795(FGF2)
PKL: 118711281(FGF2)
HAI: 109374154(FGF2)
DRO: 112312217(FGF2)
SHON: 118995576(FGF2)
AJM: 119037695(FGF2)
PDIC: 114502553(FGF2)
PHAS: 123813667(FGF2)
MMF: 118616042(FGF2)
RFQ: 117037862(FGF2)
PALE: 107196088(FGF2)
PGIG: 120616271(FGF2)
RAY: 107518501(FGF2)
SARA: 101555369(FGF2)
LAV: 100657533(FGF2)
TMU: 101342442
DNM: 101423570(FGF2)
MDO: 619384(FGF2)
GAS: 123251436(FGF2)
SHR: 100934542(FGF2)
PCW: 110222958(FGF2)
OAA: 114815531(FGF2)
GGA: 396413(FGF2)
PCOC: 116231214(FGF2)
MGP: 100550388(FGF2)
CJO: 107313543(FGF2)
NMEL: 110398111(FGF2)
APLA: 101798064(FGF2)
ACYG: 106042430(FGF2)
AFUL: 116488431(FGF2)
TGU: 100227798(FGF2)
LSR: 110484373(FGF2)
SCAN: 103821418(FGF2)
PMOA: 120508667(FGF2)
OTC: 121339852(FGF2)
PRUF: 121361519(FGF2)
GFR: 102035880(FGF2)
FAB: 101807010(FGF2)
PHI: 102104728(FGF2)
PMAJ: 107202986(FGF2)
CCW: 120409622(FGF2)
ETL: 114061094(FGF2)
ZAB: 102068443(FGF2)
FPG: 101918253(FGF2)
FCH: 102054561(FGF2)
CLV: 110364865(FGF2)
ACUN: 113479640(FGF2)
TALA: 116962816(FGF2)
PADL: 103926140(FGF2)
ACHC: 115343528(FGF2)
AAM: 106491847(FGF2)
AROW: 112973481(FGF2)
NPD: 112950246(FGF2)
DNE: 112996800(FGF2)
ASN: 102385563(FGF2)
AMJ: 102567370(FGF2)
CPOO: 109309334(FGF2)
GGN: 109301132(FGF2)
PSS: 102444616(FGF2)
CMY: 102931444(FGF2)
CPIC: 122174672(FGF2)
CABI: 116834788(FGF2)
MRV: 120406846(FGF2)
ACS: 100559071(fgf2)
PVT: 110072861(FGF2)
SUND: 121931107(FGF2)
PBI: 103053614(FGF2)
PMUR: 107283368(FGF2)
TSR: 106542651(FGF2)
PGUT: 117654575(FGF2)
PMUA: 114604525(FGF2)
ZVI: 118083517(FGF2)
GJA: 107109560(FGF2)
XLA: 100101279(fgf2) 108706695(fgf2.S)
XTR: 550087(fgf2)
NPR: 108790780(FGF2)
RTEM: 120918763(FGF2)
BBUF: 120989950(FGF2)
BGAR: 122944017(FGF2)
DRE: 404231(fgf2)
SANH: 107694403(fgf2) 107700884
SGH: 107559624(fgf1) 107568661
CCAR: 109065695
IPU: 108258196(fgf2)
PHYP: 113528646
SMEO: 124396724(fgf2)
AMEX: 103037892(fgf2)
EEE: 113589363(fgf2)
TRU: 115252306
LCO: 104931006(fgf2)
NCC: 104957748(fgf2)
CGOB: 115014705(fgf2)
ELY: 117260751(fgf2)
PLEP: 121947824(fgf2)
SLUC: 116062503(fgf2)
ECRA: 117951309(fgf2)
PFLV: 114563146(fgf2)
GAT: 120817426(fgf2)
PPUG: 119210066(fgf2)
MSAM: 119889114(fgf2)
CUD: 121516087(fgf2)
MZE: 101483487(fgf2)
ONL: 100696875(fgf2)
OAU: 116322839(fgf2)
OML: 112151220(fgf2)
XMA: 102225642(fgf2)
XCO: 114139089(fgf2)
XHE: 116714813(fgf2)
PRET: 103471877(fgf2)
PFOR: 103137295(fgf2)
PLAI: 106948218(fgf2)
PMEI: 106924838(fgf2)
GAF: 122836704(fgf2)
CVG: 107099215(fgf2)
CTUL: 119798711(fgf2)
NFU: 107380334(fgf2)
KMR: 108236605(fgf2)
NWH: 119408776(fgf2)
AOCE: 111570066(fgf2)
CSEM: 103390695(fgf2)
POV: 109641290(fgf2)
SSEN: 122778971(fgf2)
HHIP: 117769009(fgf2)
LCF: 108901525(fgf2)
SDU: 111232376(fgf2)
SLAL: 111644654(fgf2)
XGL: 120785334(fgf2)
HCQ: 109529054(fgf2)
BPEC: 110153728(fgf2)
MALB: 109956730(fgf2)
SASA: 106604591 106611625(fgf2)
OTW: 112244661 112256299(fgf2)
OMY: 100136280 110505088(fgf2)
SALP: 111965796 111967553(fgf2)
ELS: 105028130(fgf2)
SFM: 108938772(fgf2)
PKI: 111832812 111835519(fgf2)
AANG: 118226718 118231483(fgf2)
LOC: 102692334(fgf2)
PSPA: 121323680(fgf2) 121328899
LCM: 102351407(FGF2)
CMK: 103188323(fgf2)
RTP: 109916889
APLC: 110983759
OTU: 111418448
EPA: 110237525
ADF: 107340900
PDAM: 113683295
SPIS: 111338817
HMG: 101235368(FGF)
 » show all
Reference
PMID:3780670
  Authors
Abraham JA, Whang JL, Tumolo A, Mergia A, Friedman J, Gospodarowicz D, Fiddes JC
  Title
Human basic fibroblast growth factor: nucleotide sequence and genomic organization.
  Journal
EMBO J 5:2523-8 (1986)
DOI:10.1002/j.1460-2075.1986.tb04530.x
  Sequence
[hsa:2247]
Reference
  Authors
Okada-Ban M, Thiery JP, Jouanneau J
  Title
Fibroblast growth factor-2.
  Journal
Int J Biochem Cell Biol 32:263-7 (2000)
DOI:10.1016/S1357-2725(99)00133-8
  Sequence
[hsa:2247]
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