KEGG   PATHWAY: ko00470
Entry
ko00470                     Pathway                                
Name
D-Amino acid metabolism
Class
Metabolism; Metabolism of other amino acids
Pathway map
ko00470  D-Amino acid metabolism
ko00470

Module
M00947  D-Arginine racemization, D-arginine => L-arginine [PATH:ko00470]
M00948  Hydroxyproline degradation, trans-4-hydroxy-L-proline => 2-oxoglutarate [PATH:ko00470]
M00949  Staphylopine biosynthesis, L-histidine => staphylopine [PATH:ko00470]
Other DBs
GO: 0046416
Orthology
K00272  DDO; D-aspartate oxidase [EC:1.4.3.1]
K00273  DAO, aao; D-amino-acid oxidase [EC:1.4.3.3]
K00285  dadA; D-amino-acid dehydrogenase [EC:1.4.5.1]
K00824  dat; D-alanine transaminase [EC:2.6.1.21]
K01425  glsA, GLS; glutaminase [EC:3.5.1.2]
K01586  lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
K01753  dsdA; D-serine dehydratase [EC:4.3.1.18]
K01775  alr; alanine racemase [EC:5.1.1.1]
K01776  murI; glutamate racemase [EC:5.1.1.3]
K01777  prdF; proline racemase [EC:5.1.1.4]
K01778  dapF; diaminopimelate epimerase [EC:5.1.1.7]
K01779  racD; aspartate racemase [EC:5.1.1.13]
K01780  cntK; histidine racemase
K01798  alr-murF; Alr-MurF fusion protein
K01844  kamD; beta-lysine 5,6-aminomutase alpha subunit [EC:5.4.3.3]
K01921  ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
K01925  murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
K03367  dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13]
K05396  dcyD; D-cysteine desulfhydrase [EC:4.4.1.15]
K05597  aspQ, ansB, ansA; glutamin-(asparagin-)ase [EC:3.5.1.38]
K10793  prdA; D-proline reductase (dithiol) PrdA [EC:1.21.4.1]
K10794  prdB; D-proline reductase (dithiol) PrdB [EC:1.21.4.1]
K12235  SRR; serine racemase [EC:5.1.1.18]
K12526  lysAC; bifunctional diaminopimelate decarboxylase / aspartate kinase [EC:4.1.1.20 2.7.2.4]
K12658  lhpA; 4-hydroxyproline epimerase [EC:5.1.1.8]
K13877  aldH; 2,5-dioxopentanoate dehydrogenase [EC:1.2.1.26]
K14188  dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13]
K17851  dpd; D-proline dehydrogenase [EC:1.5.99.13]
K17898  oraE; D-ornithine 4,5-aminomutase subunit beta [EC:5.4.3.5]
K17899  oraS; D-ornithine 4,5-aminomutase subunit alpha [EC:5.4.3.5]
K18011  kamE; beta-lysine 5,6-aminomutase beta subunit [EC:5.4.3.3]
K18852  HPA3; D-amino-acid N-acetyltransferase [EC:2.3.1.36]
K19588  dopDH; 2,5-dioxopentanoate dehydrogenase [EC:1.2.1.26]
K19744  dauB; L-arginine dehydrogenase [EC:1.4.1.25]
K19746  dauA; D-arginine dehydrogenase [EC:1.4.99.6]
K19802  ycjG, ykfB, dgcA; L-Ala-D/L-Glu epimerase / N-acetyl-D-glutamate racemase [EC:5.1.1.20 5.1.1.25]
K19967  dta; D-threonine aldolase [EC:4.1.2.42]
K20498  DSD1; D-serine ammonia-lyase [EC:4.3.1.18]
K21060  lhpB; D-hydroxyproline dehydrogenase [EC:1.5.99.-]
K21061  lhpB; D-hydroxyproline dehydrogenase subunit beta [EC:1.5.99.-]
K21062  lhpC; 1-pyrroline-4-hydroxy-2-carboxylate deaminase [EC:3.5.4.22]
K21672  ord; 2,4-diaminopentanoate dehydrogenase [EC:1.4.1.12 1.4.1.26]
K21898  orr; ornithine racemase [EC:5.1.1.12]
K22210  DGLUCY; D-glutamate cyclase [EC:4.2.1.48]
K22549  lhpC; D-hydroxyproline dehydrogenase subunit alpha [EC:1.5.99.-]
K22550  lhpD; D-hydroxyproline dehydrogenase subunit gamma
K23120  cntL; histidine 2-aminobutanoyltransferase
K23122  cntM; staphylopine/pseudopaline/yersinopine synthase
K23265  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase
K23385  dokD; D-ornithine/D-lysine decarboxylase
K25316  racX, ygeA; amino-acid racemase
K25317  alr, bsrV; amino-acid racemase
K25364  LK; lombricine kinase
K25365  gbh; guanidinobutyrase / D-arginase
K26272  dgcN; D-glutamate N-acetyltransferase
K29026  aar; alanine/glutamate racemase
Compound
C00022  Pyruvate
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00036  Oxaloacetate
C00037  Glycine
C00041  L-Alanine
C00047  L-Lysine
C00049  L-Aspartate
C00062  L-Arginine
C00064  L-Glutamine
C00065  L-Serine
C00073  L-Methionine
C00077  L-Ornithine
C00079  L-Phenylalanine
C00084  Acetaldehyde
C00097  L-Cysteine
C00133  D-Alanine
C00134  Putrescine
C00135  L-Histidine
C00148  L-Proline
C00166  Phenylpyruvate
C00188  L-Threonine
C00217  D-Glutamate
C00402  D-Aspartate
C00431  5-Aminopentanoate
C00433  2,5-Dioxopentanoate
C00515  D-Ornithine
C00624  N-Acetyl-L-glutamate
C00666  LL-2,6-Diaminoheptanedioate
C00680  meso-2,6-Diaminoheptanedioate
C00692  UDP-N-acetylmuramoyl-L-alanyl-D-glutamate
C00739  D-Lysine
C00740  D-Serine
C00763  D-Proline
C00792  D-Arginine
C00793  D-Cysteine
C00819  D-Glutamine
C00820  D-Threonine
C00855  D-Methionine
C00993  D-Alanyl-D-alanine
C01110  5-Amino-2-oxopentanoic acid
C01157  Hydroxyproline
C01180  4-Methylthio-2-oxobutanoic acid
C01667  Bacitracin
C01672  Cadaverine
C01726  D-Lombricine
C02237  5-Oxo-D-proline
C02265  D-Phenylalanine
C02855  N-Phospho-D-lombricine
C03239  6-Amino-2-oxohexanoate
C03341  2-Amino-4-oxopentanoic acid
C03440  cis-4-Hydroxy-D-proline
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03933  5-D-Glutamyl-D-glutamyl-peptide
C03943  (2R,4S)-2,4-Diaminopentanoate
C04260  O-D-Alanyl-poly(ribitol phosphate)
C04282  1-Pyrroline-4-hydroxy-2-carboxylate
C04457  D-Alanyl-alanyl-poly(glycerolphosphate)
C05161  (2R,5S)-2,5-Diaminohexanoate
C05620  N-Acetyl-D-phenylalanine
C05825  2-Amino-5-oxohexanoate
C05939  Linatine
C05941  2-Oxo-4-hydroxy-5-aminovalerate
C05942  Pyrrole-2-carboxylate
C06419  D-Histidine
C22024  Staphylopine
C22025  (2S)-2-Amino-4-{[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate
C22611  N-Acetyl-D-glutamate
Reference
PMID:33788945
  Authors
Miyamoto T, Homma H
  Title
D-Amino acid metabolism in bacteria.
  Journal
J Biochem 170:5-13 (2021)
DOI:10.1093/jb/mvab043
Reference
PMID:27230378
  Authors
Ghssein G, Brutesco C, Ouerdane L, Fojcik C, Izaute A, Wang S, Hajjar C, Lobinski R, Lemaire D, Richaud P, Voulhoux R, Espaillat A, Cava F, Pignol D, Borezee-Durant E, Arnoux P
  Title
Biosynthesis of a broad-spectrum nicotianamine-like metallophore in Staphylococcus aureus.
  Journal
Science 352:1105-9 (2016)
DOI:10.1126/science.aaf1018
Related
pathway
ko00010  Glycolysis / Gluconeogenesis
ko00020  Citrate cycle (TCA cycle)
ko00250  Alanine, aspartate and glutamate metabolism
ko00260  Glycine, serine and threonine metabolism
ko00270  Cysteine and methionine metabolism
ko00300  Lysine biosynthesis
ko00310  Lysine degradation
ko00330  Arginine and proline metabolism
ko00340  Histidine metabolism
ko00360  Phenylalanine metabolism
ko00550  Peptidoglycan biosynthesis
ko00620  Pyruvate metabolism

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