KEGG   PATHWAY: ko00470
Entry
ko00470                     Pathway                                
Name
D-Amino acid metabolism
Class
Metabolism; Metabolism of other amino acids
Pathway map
ko00470  D-Amino acid metabolism
ko00470

Module
M00947  D-Arginine racemization, D-arginine => L-arginine [PATH:ko00470]
M00948  Hydroxyproline degradation, trans-4-hydroxy-L-proline => 2-oxoglutarate [PATH:ko00470]
M00949  Staphylopine biosynthesis, L-histidine => staphylopine [PATH:ko00470]
Other DBs
GO: 0046416
Orthology
K01775  alanine racemase [EC:5.1.1.1]
K01798  Alr-MurF fusion protein [EC:5.1.1.1 6.3.2.10]
K00824  D-alanine transaminase [EC:2.6.1.21]
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
K03367  D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13]
K14188  D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13]
K25316  amino-acid racemase [EC:5.1.1.10]
K25317  amino-acid racemase [EC:5.1.1.10]
K01425  glutaminase [EC:3.5.1.2]
K23265  phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
K05597  glutamin-(asparagin-)ase [EC:3.5.1.38]
K01776  glutamate racemase [EC:5.1.1.3]
K01925  UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
K22210  D-glutamate cyclase [EC:4.2.1.48]
K26272  D-glutamate N-acetyltransferase [EC:2.3.1.312]
K19802  L-Ala-D/L-Glu epimerase / N-acetyl-D-glutamate racemase [EC:5.1.1.20 5.1.1.25]
K01779  aspartate racemase [EC:5.1.1.13]
K00272  D-aspartate oxidase [EC:1.4.3.1]
K12235  serine racemase [EC:5.1.1.18]
K20498  D-serine ammonia-lyase [EC:4.3.1.18]
K01753  D-serine dehydratase [EC:4.3.1.18]
K25364  lombricine kinase [EC:2.7.3.5]
K19967  D-threonine aldolase [EC:4.1.2.42]
K05396  D-cysteine desulfhydrase [EC:4.4.1.15]
K01778  diaminopimelate epimerase [EC:5.1.1.7]
K01586  diaminopimelate decarboxylase [EC:4.1.1.20]
K12526  bifunctional diaminopimelate decarboxylase / aspartate kinase [EC:4.1.1.20 2.7.2.4]
K01844  beta-lysine 5,6-aminomutase alpha subunit [EC:5.4.3.3]
K18011  beta-lysine 5,6-aminomutase beta subunit [EC:5.4.3.3]
K21672  2,4-diaminopentanoate dehydrogenase [EC:1.4.1.12 1.4.1.26]
K23385  D-ornithine/D-lysine decarboxylase [EC:4.1.1.116]
K00273  D-amino-acid oxidase [EC:1.4.3.3]
K19746  D-arginine dehydrogenase [EC:1.4.99.6]
K19744  L-arginine dehydrogenase [EC:1.4.1.25]
K25365  guanidinobutyrase / D-arginase [EC:3.5.3.7 3.5.3.10]
K21898  ornithine racemase [EC:5.1.1.12]
K17898  D-ornithine 4,5-aminomutase subunit beta [EC:5.4.3.5]
K17899  D-ornithine 4,5-aminomutase subunit alpha [EC:5.4.3.5]
K01777  proline racemase [EC:5.1.1.4]
K17851  D-proline dehydrogenase [EC:1.5.99.13]
K10793  D-proline reductase (dithiol) PrdA [EC:1.21.4.1]
K10794  D-proline reductase (dithiol) PrdB [EC:1.21.4.1]
K12658  4-hydroxyproline epimerase [EC:5.1.1.8]
K21060  D-hydroxyproline dehydrogenase [EC:1.5.99.-]
K22549  D-hydroxyproline dehydrogenase subunit alpha [EC:1.5.99.-]
K21061  D-hydroxyproline dehydrogenase subunit beta [EC:1.5.99.-]
K22550  D-hydroxyproline dehydrogenase subunit gamma
K21062  1-pyrroline-4-hydroxy-2-carboxylate deaminase [EC:3.5.4.22]
K13877  2,5-dioxopentanoate dehydrogenase [EC:1.2.1.26]
K19588  2,5-dioxopentanoate dehydrogenase [EC:1.2.1.26]
K01780  histidine racemase [EC:5.1.1.24]
K23120  histidine 2-aminobutanoyltransferase [EC:2.5.1.152 2.5.1.-]
K23122  staphylopine/pseudopaline/yersinopine synthase [EC:1.5.1.52 1.5.1.-]
K00285  D-amino-acid dehydrogenase [EC:1.4.5.1]
K18852  D-amino-acid N-acetyltransferase [EC:2.3.1.36]
Compound
C00022  Pyruvate
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00036  Oxaloacetate
C00037  Glycine
C00041  L-Alanine
C00047  L-Lysine
C00049  L-Aspartate
C00062  L-Arginine
C00064  L-Glutamine
C00065  L-Serine
C00073  L-Methionine
C00077  L-Ornithine
C00079  L-Phenylalanine
C00084  Acetaldehyde
C00097  L-Cysteine
C00133  D-Alanine
C00134  Putrescine
C00135  L-Histidine
C00148  L-Proline
C00166  Phenylpyruvate
C00188  L-Threonine
C00217  D-Glutamate
C00402  D-Aspartate
C00431  5-Aminopentanoate
C00433  2,5-Dioxopentanoate
C00515  D-Ornithine
C00624  N-Acetyl-L-glutamate
C00666  LL-2,6-Diaminoheptanedioate
C00680  meso-2,6-Diaminoheptanedioate
C00692  UDP-N-acetylmuramoyl-L-alanyl-D-glutamate
C00739  D-Lysine
C00740  D-Serine
C00763  D-Proline
C00792  D-Arginine
C00793  D-Cysteine
C00819  D-Glutamine
C00820  D-Threonine
C00855  D-Methionine
C00993  D-Alanyl-D-alanine
C01110  5-Amino-2-oxopentanoic acid
C01157  Hydroxyproline
C01180  4-Methylthio-2-oxobutanoic acid
C01667  Bacitracin
C01672  Cadaverine
C01726  D-Lombricine
C02237  5-Oxo-D-proline
C02265  D-Phenylalanine
C02855  N-Phospho-D-lombricine
C03239  6-Amino-2-oxohexanoate
C03341  2-Amino-4-oxopentanoic acid
C03440  cis-4-Hydroxy-D-proline
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03933  5-D-Glutamyl-D-glutamyl-peptide
C03943  (2R,4S)-2,4-Diaminopentanoate
C04260  O-D-Alanyl-poly(ribitol phosphate)
C04282  1-Pyrroline-4-hydroxy-2-carboxylate
C04457  D-Alanyl-alanyl-poly(glycerolphosphate)
C05161  (2R,5S)-2,5-Diaminohexanoate
C05620  N-Acetyl-D-phenylalanine
C05825  2-Amino-5-oxohexanoate
C05939  Linatine
C05941  2-Oxo-4-hydroxy-5-aminovalerate
C05942  Pyrrole-2-carboxylate
C06419  D-Histidine
C22024  Staphylopine
C22025  (2S)-2-Amino-4-{[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate
C22611  N-Acetyl-D-glutamate
Reference
PMID:33788945
  Authors
Miyamoto T, Homma H
  Title
D-Amino acid metabolism in bacteria.
  Journal
J Biochem 170:5-13 (2021)
DOI:10.1093/jb/mvab043
Reference
PMID:27230378
  Authors
Ghssein G, Brutesco C, Ouerdane L, Fojcik C, Izaute A, Wang S, Hajjar C, Lobinski R, Lemaire D, Richaud P, Voulhoux R, Espaillat A, Cava F, Pignol D, Borezee-Durant E, Arnoux P
  Title
Biosynthesis of a broad-spectrum nicotianamine-like metallophore in Staphylococcus aureus.
  Journal
Science 352:1105-9 (2016)
DOI:10.1126/science.aaf1018
Related
pathway
ko00010  Glycolysis / Gluconeogenesis
ko00020  Citrate cycle (TCA cycle)
ko00250  Alanine, aspartate and glutamate metabolism
ko00260  Glycine, serine and threonine metabolism
ko00270  Cysteine and methionine metabolism
ko00300  Lysine biosynthesis
ko00310  Lysine degradation
ko00330  Arginine and proline metabolism
ko00340  Histidine metabolism
ko00360  Phenylalanine metabolism
ko00550  Peptidoglycan biosynthesis
ko00620  Pyruvate metabolism
LinkDB

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