Entry  
 
Symbol  
miaA, TRIT1 
 
Name  
tRNA dimethylallyltransferase [EC:
2.5.1.75 ]
 
Pathway  
map01110   Biosynthesis of secondary metabolites 
 
Reaction  
R01122   delta2-isopentenyl-diphosphate:tRNA isopentenyltransferase 
 
Disease  
H00891   Combined oxidative phosphorylation deficiency 
 
Brite  
KEGG Orthology (KO) [BR:ko00001 ] 
 09100 Metabolism 
  09109 Metabolism of terpenoids and polyketides 
   00908 Zeatin biosynthesis 
    K00791  miaA, TRIT1; tRNA dimethylallyltransferase 
 09180 Brite Hierarchies 
  09181 Protein families: metabolism 
   01006 Prenyltransferases 
    K00791  miaA, TRIT1; tRNA dimethylallyltransferase 
  09182 Protein families: genetic information processing 
   03016 Transfer RNA biogenesis 
    K00791  miaA, TRIT1; tRNA dimethylallyltransferase 
Enzymes [BR:ko01000 ] 
 2. Transferases 
  2.5  Transferring alkyl or aryl groups, other than methyl groups 
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date) 
    2.5.1.75  tRNA dimethylallyltransferase 
     K00791  miaA, TRIT1; tRNA dimethylallyltransferase 
Prenyltransferases [BR:ko01006 ] 
 Compound prenylation 
  tRNA dimethylallyltransferase 
   K00791  miaA, TRIT1; tRNA dimethylallyltransferase 
Transfer RNA biogenesis [BR:ko03016 ] 
 Eukaryotic type 
  tRNA modification factors 
   Other tRNA modification factors 
    K00791  miaA, TRIT1; tRNA dimethylallyltransferase 
 Prokaryotic type 
  tRNA modification factors 
   Other tRNA modification factors 
    K00791  miaA, TRIT1; tRNA dimethylallyltransferase 
 BRITE hierarchy  
Other DBs  
 
Genes  
 » show all  
Taxonomy UniProt  
Reference  
 
  Authors  
Leung HC, Chen Y, Winkler ME
 
  Title  
Regulation of substrate recognition by the MiaA tRNA prenyltransferase modification enzyme of Escherichia coli K-12.
 
  Journal  
 
Reference  
 
  Authors  
Golovko A, Hjalm G, Sitbon F, Nicander B
 
  Title  
Cloning of a human tRNA isopentenyl transferase.
 
  Journal  
 
  Sequence  
 
Reference  
 
  Authors  
Miyawaki K, Tarkowski P, Matsumoto-Kitano M, Kato T, Sato S, Tarkowska D, Tabata S, Sandberg G, Kakimoto T
 
  Title  
Roles of Arabidopsis ATP/ADP isopentenyltransferases and tRNA isopentenyltransferases in cytokinin biosynthesis.
 
  Journal  
 
Reference  
 
  Authors  
Connolly DM, Winkler ME
 
  Title  
Genetic and physiological relationships among the miaA gene, 2-methylthio-N6-(delta 2-isopentenyl)-adenosine tRNA modification, and spontaneous mutagenesis in Escherichia coli K-12.
 
  Journal  
 
  Sequence  
 
LinkDB  
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