KEGG ORTHOLOGY: K17821

ORTHOLOGY: K17821

Entry

K17821                      KO

Symbol

RNF165

Name

E3 ubiquitin-protein ligase RNF165 [EC:2.3.2.27]

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K17821  RNF165; E3 ubiquitin-protein ligase RNF165
Enzymes [BR:ko01000]
2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     K17821  RNF165; E3 ubiquitin-protein ligase RNF165
Ubiquitin system [BR:ko04121]
Ubiquitin ligases (E3)
  Single Ring-finger type E3
   Other single Ring-finger type E3
    K17821  RNF165; E3 ubiquitin-protein ligase RNF165

Genes

HSA:	494470(ARK2C)

PTR:	455400(ARK2C)

PPS:	100967299(ARK2C)

GGO:	101129543(ARK2C)

PON:	100452536(ARK2C)

PPYG:

129018718(ARK2C)

NLE:	100579724(RNF165)

HMH:	116468574(ARK2C)

SSYN:

129457969(ARK2C)

MCC:	702104(RNF165)

MCF:	102122095(ARK2C)

MTHB:

126941417

MNI:	105499599(RNF165)

CSAB:

103222474(RNF165)

CATY:

105592533(RNF165)

PANU:

100999191(RNF165)

TGE:	112611437(RNF165)

MLEU:

105538273(RNF165)

RRO:	104680749(RNF165)

RBB:	108519046(RNF165)

TFN:	117063940(RNF165)

PTEH:

111539687(RNF165)

CANG:

105517000(RNF165)

CJC:	100389104(ARK2C)

SBQ:	101034185(RNF165)

CIMI:

108305141(RNF165)

ANAN:

105709058(ARK2C)

CSYR:

103262409(RNF165)

MMUR:

105885410(RNF165)

LCAT:

123621480(RNF165)

ERUF:

138383304(ARK2C)

PCOQ:

105808889(RNF165)

OGA:	100963694(RNF165)

MMU:	225743(Ark2c)

MCAL:

110284873(Rnf165)

MPAH:

110333082(Rnf165)

RNO:	307251(Ark2c)

MCOC:

116087377(Rnf165)

ANU:	117719864(Rnf165)

ASYL:

127663971(Ark2c)

MUN:	110553534(Ark2c)

CGE:	100769567(Rnf165)

MAUA:

101833426(Rnf165)

PROB:

127235000(Ark2c)

PLEU:

114694891(Rnf165)

PMAV:

102908000(Ark2c)

MORG:

121440140(Rnf165)

MFOT:

126507348

AAMP:

119815831(Rnf165)

CNL:	130886940(Ark2c)

NGI:	103727844(Rnf165)

HGL:	101707502(Rnf165)

CPOC:

100718877(Rnf165)

CCAN:

109698799(Rnf165)

DORD:

105984632(Rnf165)

DSP:	122104393(Rnf165)

DMER:

138831572(Ark2c)

PLOP:

125363901(Rnf165)

NCAR:

124965381

MMMA:

107139322(Rnf165)

ITI:	101976726(Rnf165)

OCU:

100357325

OPI:	101532671(RNF165)

OCZ:	121159550(RNF165)

TUP:	102489308(RNF165)

GVR:	103590564(RNF165)

CFA:	490468(RNF165)

CLUD:

112647788(RNF165)

VVP:	112918793(RNF165)

VLG:	121489979(RNF165)

NPO:	129508985(ARK2C)

AML:	100468493(RNF165)

UMR:	103665163(RNF165)

UAH:	113253378(ARK2C)

UAR:	123787357(RNF165)

ELK:

111142641

LLV:

125082711

MPUF:

101672234(RNF165)

MNP:	132023946(ARK2C)

MLK:	131811656(ARK2C)

NVS:	122903568(RNF165)

ORO:	101381877(RNF165)

EJU:	114205058(RNF165)

ZCA:	113913132(RNF165)

MLX:	118004516(RNF165)

MANO:

135362609

NSU:	110577087(RNF165)

LWW:	102743151(RNF165)

FCA:	101085411(RNF165)

PYU:	121032973(RNF165)

PCOO:

112868181(RNF165)

PBG:	122470738(RNF165)

PVIV:

125149699(ARK2C)

LRUF:

124517111

LGF:	123588059(RNF165)

AJU:

106972940

PTG:	102951265(RNF165)

PPAD:

109275769(RNF165)

PUC:

125914306

HHV:	120229716(RNF165)

BTA:	537072(RNF165)

BIU:	109577672(RNF165)

BBUB:

102391962(RNF165)

BKE:	129635844(ARK2C)

BBIS:

104990105(RNF165)

CHX:	102181551(RNF165)

OAS:	101109848(ARK2C)

BTAX:

128067552(ARK2C)

CSUM:

138097704(ARK2C)

ODA:	120881020(RNF165)

CCAD:

122425821(RNF165)

MREE:

136167668(ARK2C)

OVR:	110123217(ARK2C)

MBEZ:

129549597(ARK2C)

SSC:	100738135(RNF165)

CFR:	102517705(RNF165)

CBAI:

105073973(RNF165)

CDK:	105097580(RNF165)

BACU:

103001822(RNF165)

BMUS:

118880330(RNF165)

LVE:	103073258(RNF165)

OOR:	101274983(ARK2C)

LALB:

132504294(ARK2C)

GMF:	115859224(ARK2C)

DDP:	132436626(ARK2C)

DLE:	111168201(RNF165)

PCAD:

102992671(ARK2C)

PSIU:

116739108(RNF165)

PPHC:

136133170(ARK2C)

NASI:

112392839(RNF165)

ECB:	100068804(RNF165)

EPZ:	103560405(ARK2C)

EAI:	106823323(RNF165)

MYB:	102260309(RNF165)

MYD:	102754896(RNF165)

MMYO:

118663767(RNF165)

MLF:	102428024(RNF165)

MDT:	132239989(ARK2C)

MYUM:

139014189(ARK2C)

PKL:	118707588(RNF165)

EFUS:

103301053(ARK2C)

MNA:	107546616(RNF165)

DRO:	112322983(RNF165)

SHON:

118978336(RNF165)

AJM:	119063674(ARK2C)

PDIC:

114506921(RNF165)

PHAS:

123825954(RNF165)

MMF:	118618852(RNF165)

PPAM:

129078891(ARK2C)

HAI:	109388193(RNF165)

RFQ:	117011915(RNF165)

PALE:

102896215(RNF165)

PGIG:

120586018(RNF165)

PVP:	105292743(RNF165)

RAY:	107512653(RNF165)

MJV:	108394925(RNF165)

TOD:	119243073(ARK2C)

SARA:

101540725(RNF165)

SFUM:

130045402(ARK2C)

SETR:

126020087 126020102

LAV:	100672702(RNF165)

TMU:

101356976

ETF:	101640889(RNF165)

DNM:	101429425(RNF165)

MDO:	100017991(RNF165)

GAS:	123252253(RNF165)

SHR:	100933881(RNF165)

AFZ:

127543530

PCW:	110207970(RNF165)

TVP:	118834335(RNF165)

OAA:	100074786(RNF165)

TACU:

119925313(RNF165)

GGA:	416382(RNF165)

PCOC:

116231363(RNF165)

MGP:	100545301(RNF165)

CJO:	107305717(RNF165)

TPAI:

128074450(ARK2C)

LMUT:

125686962(RNF165)

NMEL:

110390157(RNF165)

APLA:

101792499(RNF165) 101795545

AACU:

137847020(ARK2C)

OJA:	118156042(RNF165)

ACYG:

106037353(ARK2C)

CATA:

118254630(ARK2C)

AFUL:

116500472(RNF165)

TGU:	100229382(RNF165)

LSR:	110475052(ARK2C)

SCAN:

103820675(RNF165)

PMOA:

120513718(RNF165)

OTC:	121346085(RNF165)

PRUF:

121351766(RNF165)

ATRC:

139589389(ARK2C)

GFR:	102033673(RNF165)

FAB:	101813074(RNF165)

OMA:	130265293(ARK2C)

PHI:	102102889(RNF165)

PMAJ:

107198449(RNF165)

CCAE:

111941020(RNF165)

CCW:	104695702(RNF165)

CBRC:

103622054(RNF165)

ACOE:

138103758(ARK2C)

ETL:	114058325(RNF165)

ZAB:	102068573(RNF165)

ZLE:	135459831(ARK2C)

ACHL:

103802321(RNF165)

SVG:	106865036(RNF165)

MMEA:

130574528(ARK2C)

HRT:	120765946(ARK2C)

SATI:

136373760(ARK2C)

CCIC:

134056786(ARK2C)

FPG:	101920044(RNF165)

FCH:	102048977(RNF165)

CCRI:

104155813(RNF165)

NNT:	104404831(RNF165)

SHAB:

115600836(RNF165)

ACUN:

113489894(RNF165)

ANOC:

141973480(ARK2C)

SURA:

141938088(ARK2C)

TALA:

104365217(RNF165)

ACHC:

115337119(RNF165)

HALD:

104323882(RNF165)

HLE:	104841410(RNF165)

AGEN:

126036335

HHAR:

128137363(ARK2C)

BBUT:

142026795(ARK2C)

GCL:

127027651

CSTI:

104563930(RNF165)

LDI:	104351532(RNF165)

MNB:	103771948(RNF165)

DPUB:

104304356(RNF165)

PPUS:

135193103(ARK2C)

AVIT:

104268526(RNF165)

BRHI:

104493373(RNF165)

EGZ:	104134199(RNF165)

PCRI:

104025319(RNF165)

PCAO:

104044105(RNF165)

PARX:

142049449 142050129(ARK2C)

PADL:

103916033(RNF165)

AFOR:

103898221(RNF165)

FGA:	104072898(RNF165)

CBOR:

142074816

GSTE:

104260565(RNF165)

CBOY:

140651013(ARK2C)

MAME:

142402902(ARK2C)

CLV:	102087327(RNF165)

CNIC:

136002340(ARK2C)

MUI:

104542484

PGUU:

104471892(RNF165)

PLET:

104618816(RNF165)

EHS:	104508990(RNF165)

CMAC:

104480167(RNF165)

CUCA:

104056272(ARK2C)

TEO:	104378088(RNF165)

BREG:

104630365(RNF165)

GAME:

129199186(ARK2C)

OHA:	104335620(RNF165)

ACAR:

104527782(RNF165)

CPEA:

104395340(RNF165)

CVF:	104290672 104295055(RNF165)

RTD:	128902092 128902902(ARK2C)

CRID:

134508823(ARK2C)

LMIC:

141736367(ARK2C)

NARQ:

141476695 141477486(ARK2C)

AAM:	106495140(RNF165)

AROW:

112975838(RNF165)

NPD:	112947615(RNF165)

TGT:	104568129 104569695 104580762

DNE:	112994471(RNF165)

ASN:	102383738(RNF165)

AMJ:	102563487(RNF165)

CPOO:

109307746(RNF165)

GGN:	109298002(RNF165)

PSS:	102462076(RNF165)

CIZ:	142013253(ARK2C)

CMY:	102944725(RNF165)

CCAY:

125636973(RNF165)

LKP:	140911114(ARK2C)

NDS:	141987197(ARK2C)

DCC:	119855381(RNF165)

CPIC:

101936666(RNF165)

TST:	117879247(RNF165)

EOB:	135880685(ARK2C)

CABI:

116818224(RNF165)

MRV:	120408289(RNF165)

ACS:	100565874(rnf165)

ASAO:

132766850(ARK2C)

PVT:	110085926(RNF165)

SUND:

121920710(RNF165)

PBI:	103062296(RNF165)

PMUR:

107297782(RNF165)

CTIG:

120306045(RNF165)

TSR:	106539039 106549012

PGUT:

117655974(ARK2C)

APRI:

131190753(ARK2C)

PTEX:

113444960(RNF165)

VKO:	123024173(RNF165)

PMUA:

114606248(RNF165)

PRAF:

128422990(ARK2C)

ZVI:	118077280(RNF165)

HCG:	128341740(ARK2C)

GJA:	107106888(RNF165)

STOW:

125436694(RNF165)

EMC:	129334885(ARK2C)

XLA:	108707350(rnf165.S) 108718737(rnf165.L)

XTR:	100487951(rnf165)

NPR:	108786439(RNF165)

RTEM:

120926437(RNF165)

ACAT:

141131594(ARK2C)

PADS:

140332273(ARK2C)

BBUF:

120991323(RNF165)

BGAR:

122936986(RNF165)

DTC:	141100985(ARK2C)

HSQ:	130293916(ARK2C)

PCOB:

135054996(ARK2C)

PWL:	138272323(ARK2C)

MUO:	115462856(RNF165)

GSH:	117355906(RNF165)

DRE:	572251(ark2ca) 572413(ark2cb)

SRX:	107705945 107712483 107726862 107726876 107737164

SANH:

107661517(rnf165) 107661570 107675698 107704592

SGH:	107569673 107573345 107585634 107599358

CCAR:

109053682 109066464 109074381(rnf165b) 109074383

CAUA:

113038927 113052640 113052820 113077143 113097273 113106885

CGIB:

127942173 127963384 127986159 128019073

PTET:

122332577(rnf165a) 122349986(rnf165b)

LROH:

127152091(rnf165a) 127169740(rnf165b)

GRF:	141286745 141287360 141292612(ark2ca)

OMC:	131528937(ark2ca) 131545667(ark2cb)

PPRM:

120463979(rnf165b) 120484190(rnf165a)

RKG:	130076740(ark2cb)

MAMB:

125252448(rnf165a) 125280318(rnf165b)

CIDE:

127503869 127517385

CERY:

137012502(ark2ca) 137026748(ark2cb)

MASI:

127414572 127423877 127429304 127431180

TROS:

130568016(ark2cb) 130570140(ark2ca)

TDW:	130407812(ark2ca) 130440015(ark2cb)

MANU:

129413836(ark2cb) 129423717(ark2ca)

PDAB:

135721473(ark2ca) 135730230(ark2cb)

IPU:	108265796(rnf165b) 108278824(rnf165a)

IFU:	128607767(rnf165b) 128622499(rnf165a)

PHYP:

113528056 113535630(rnf165)

SMEO:

124397622(rnf165a) 124399898(rnf165b)

TFD:	113634707(rnf165a) 113656198(rnf165b)

TVC:	132853218(ark2cb) 132860377(ark2ca)

CGAR:

128508031(rnf165a) 128530168(rnf165b)

NGRA:

132893074(ark2cb) 132895278(ark2ca)

TRN:	134317569(ark2cb) 134330450(ark2ca)

AMEX:

103024953(rnf165b) 103035273(rnf165a)

CMAO:

118813458(rnf165b) 118820221(rnf165a)

EEE:	113571019 113591764(rnf165)

CHAR:

105891470(rnf165b)

SPIL:

134089277(ark2cb)

ASAD:

121715360(rnf165b)

TRU:	101070511 101070551

TFS:	130517107(ark2ca) 130526559(ark2cb)

TNG:	GSTEN00012300G001 GSTEN00030933G001

LCO:

104924486

NCC:	104954465 104963335

TBEN:

117472476(rnf165b) 117478739(rnf165a)

CGOB:

115013272 115016742(rnf165)

PGEO:

117452895(ark2cb)

GACU:

117558623(rnf165b) 117561954(rnf165a)

EMAC:

134868812(ark2ca) 134873627(ark2cb)

ELY:	117252947(rnf165b) 117269291(rnf165a)

EFO:	125890988(rnf165b) 125905909(rnf165a)

PLEP:

121944298(rnf165b) 121959440(rnf165a)

SLUC:

116054022(rnf165b) 116062855(rnf165a)

ECRA:

117944688(rnf165b) 117959399(rnf165a)

ESP:	116689882 116704799

PFLV:

114555544 114570714(rnf165)

GAT:	120830860(rnf165b) 120831939(rnf165a)

PPUG:

119224993(ark2cb) 119226706(ark2ca)

AFB:	129101174(ark2cb) 129102339(ark2ca)

CLUM:

117736105(rnf165b) 117740461(rnf165a)

PSWI:

130196660(ark2cb) 130204991(ark2ca)

CANA:

137784237(ark2ca) 137805263(ark2cb)

CVE:	137866919(ark2cb) 137869353(ark2ca)

MSAM:

119891188(rnf165b) 119914395(rnf165a)

SCHU:

122865148(rnf165a) 122876910(rnf165b)

EARM:

139284409(ark2cb) 139301599(ark2ca)

CUD:	121509830(rnf165b) 121525685(rnf165a)

SPUL:

138602464(ark2ca) 138610192(ark2cb)

LMIX:

132974569(ark2cb) 132991956(ark2ca)

HTC:	141790312(ark2cb) 141805348(ark2ca)

ALAT:

119019091(rnf165b) 119030222(rnf165a)

ASTR:

137592770(ark2cb) 137608528(ark2ca)

PKLU:

139203819(ark2cb) 139218609(ark2ca)

MZE:	101475525 101477934(rnf165)

ONL:	100695851 100705592

OAU:	116310512(rnf165b) 116331799(rnf165a)

OLA:	101161644 101169794

OML:	112148320(rnf165b) 112163243(rnf165a)

CSAI:

133450624(ark2cb) 133454960(ark2ca)

XMA:	102218835 102231835

XCO:	114150075 114154353

XHE:	116724845 116729350

PRET:

103470112 103473450

PFOR:

103141773 103155154(rnf165)

PLAI:

106944956 106963328(rnf165)

PMEI:

106912645(rnf165) 106924720

GAF:	122827660(rnf165b) 122846814(rnf165a)

PPRL:

129365866(ark2cb) 129374147(ark2ca)

CVG:	107081404 107086292 107088956(rnf165)

CTUL:

119776524(rnf165a) 119798545(rnf165b)

GMU:	124872087(rnf165a) 124877674(rnf165b)

NFU:	107374751(rnf165) 107394135

KMR:	108231039(rnf165a) 108233736(rnf165b)

ALIM:

106513686 106535980

NWH:	119413908(rnf165b) 119425158(rnf165a)

AOCE:

111569800(ark2ca) 111573493(ark2cb)

EJA:	138191612(ark2cb) 138210425(ark2ca)

BFRE:

138621495(ark2cb) 138630970(ark2ca)

MCEP:

124996873(rnf165a) 125012219(rnf165b)

CSEM:

103390447(rnf165) 103396974 103397655

POV:	109626235 109637064

SSEN:

122758071(rnf165a) 122769489(rnf165b)

SSOE:

131446039(ark2ca) 131463681(ark2cb)

HHIP:

117768536(rnf165b) 117771749(rnf165a)

HSP:	118114953(rnf165b) 118125610(rnf165a)

PPLT:

128425266(ark2ca) 128438300(ark2cb)

SMAU:

118285326(rnf165a) 118313716(rnf165b)

LCF:	108874049(rnf165a) 108882291(rnf165b)

SDU:	111230924 111239900

SLAL:

111645152 111656790

XGL:	120805758(rnf165b) 120806819(rnf165a)

HCQ:	109520423 109526642

SSCV:

125979577(ark2ca) 125993734(ark2cb)

SBIA:

133490856(ark2ca) 133498882(ark2cb)

PEE:	133399924(ark2cb) 133414039(ark2ca)

PTAO:

133475209(ark2cb) 133490259(ark2ca)

BPEC:

110157558 110167052

ENY:	140347166(ark2cb) 140367885(ark2ca)

MALB:

109956555 109972331(rnf165)

BSPL:

114861530(ark2cb) 114866748(ark2ca)

SJO:	128365113(rnf165b) 128380461(rnf165a)

SSCO:

133979478(ark2cb) 133995546(ark2ca)

TTY:	137171389(ark2ca) 137199127(ark2cb)

GMH:	115532183 115545043(rnf165)

SASA:

106562926 106569393(rnf165) 106580569 106585175

STRU:

115159875(rnf165) 115164209 115200437 115203808

OTW:	112220151(rnf165a) 112230917 112248797 112262612

OMY:	110509561 110523346 110525947 110536329

OGO:	123989330 124036544

ONE:	115101114 115111851 115120222

OKI:	109868030 109874191 109882890 109896143

OKE:	118358531 118393469

OMM:	135513840 135544544

OCLA:

139388075 139389861 139408457 139411144

SALP:

111957448 111961839 111963805 111974584

SNH:	120021536 120026075 120044543 120063391

SFON:

129818172(ark2ca) 129826726 129853818 129863689

CCLU:

121541457 121581875 121582138 121585101

ELS:	105006100(rnf165) 105014090

OEP:	134012067(ark2cb) 134033353(ark2ca)

SFM:	108924951(rnf165) 108938139

PKI:	111849777(rnf165) 111856569

AANG:

118206298 118212840

AROT:

135233519(ark2cb) 135239885

CCOG:

133140525(ark2cb) 133141577

LOC:	102697865(rnf165)

PSPA:

121299519 121318599

ARUT:

117408668 117420882

PSEX:

120527336(rnf165a)

LCM:	102365194(RNF165)

RTP:	109916017(rnf165a)

CPLA:

122561770(rnf165a)

CPUN:

140480330(ark2ca)

HOC:	132818148(ark2ca)

SCAU:

119963947(rnf165a)

LERI:

129709635(ark2ca)

HAKA:

140726222(ark2ca)

SKO:

102801940

CQU:	CpipJ_CPIJ016186

MGEN:

CGIG:

TPRE:

CGLO:

FAS:

AGIF:

PMAC:

HHAL:

SDM:

BGT:

BRP:

BNA:

RSZ:

GTT:	GUITHDRAFT_153770

» show all

Reference

PMID:23610558

Authors

Kelly CE, Thymiakou E, Dixon JE, Tanaka S, Godwin J, Episkopou V

Title

Rnf165/Ark2C enhances BMP-Smad signaling to mediate motor axon extension.

Journal

PLoS Biol 11:e1001538 (2013)
DOI:10.1371/journal.pbio.1001538

Sequence

[mmu:225743]

LinkDB

DBGET integrated database retrieval system