KEGG   PATHWAY: asao00230
Entry
asao00230                   Pathway                                
Name
Purine metabolism - Anolis sagrei ordinatus (Brown anole)
Class
Metabolism; Nucleotide metabolism
Pathway map
asao00230  Purine metabolism
asao00230

Module
asao_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:asao00230]
asao_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:asao00230]
asao_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:asao00230]
asao_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:asao00230]
asao_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:asao00230]
asao_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:asao00230]
Other DBs
GO: 0006163 0042278
Organism
Anolis sagrei ordinatus (Brown anole) [GN:asao]
Gene
132775676  NUDT9; ADP-ribose pyrophosphatase, mitochondrial isoform X1 [KO:K13988] [EC:3.6.1.13]
132768542  ADPRM; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
132776527  NUDT5; ADP-sugar pyrophosphatase isoform X1 [KO:K13987] [EC:3.6.1.13 3.6.1.58 2.7.7.96]
132776326  PGM2; phosphopentomutase [KO:K15779] [EC:5.4.2.2 5.4.2.7]
132771672  PRPS2; ribose-phosphate pyrophosphokinase 2 isoform X1 [KO:K00948] [EC:2.7.6.1]
132762917  PRPS1; ribose-phosphate pyrophosphokinase 1 [KO:K00948] [EC:2.7.6.1]
132776661  PPAT; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
132771882  trifunctional purine biosynthetic protein adenosine-3-like [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
132771886  GART; trifunctional purine biosynthetic protein adenosine-3 [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
132777672  phosphoribosylformylglycinamidine synthase-like [KO:K01952] [EC:6.3.5.3]
132777676  phosphoribosylformylglycinamidine synthase-like [KO:K01952] [EC:6.3.5.3]
132776662  PAICS; bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase [KO:K01587] [EC:4.1.1.21 6.3.2.6]
132775969  ADSL; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
132778441  ATIC; bifunctional purine biosynthesis protein ATIC [KO:K00602] [EC:2.1.2.3 3.5.4.10]
132783288  APRT; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
132770908  NT5C2; cytosolic purine 5'-nucleotidase isoform X1 [KO:K01081] [EC:3.1.3.5]
132771100  cytosolic 5'-nucleotidase 1A-like [KO:K01081] [EC:3.1.3.5]
132782125  NT5M; 5'(3')-deoxyribonucleotidase, mitochondrial [KO:K01081] [EC:3.1.3.5]
132782448  NT5C1B; cytosolic 5'-nucleotidase 1B [KO:K01081] [EC:3.1.3.5]
132782588  NT5DC4; 5'-nucleotidase domain-containing protein 4 [KO:K01081] [EC:3.1.3.5]
132768630  NT5C; 5'(3')-deoxyribonucleotidase, cytosolic type [KO:K01081] [EC:3.1.3.5]
132780391  NT5C1A; cytosolic 5'-nucleotidase 1A [KO:K01081] [EC:3.1.3.5]
132760775  NT5E; 5'-nucleotidase [KO:K19970] [EC:3.1.3.5]
132772990  purine nucleoside phosphorylase-like [KO:K03783] [EC:2.4.2.1]
132772991  purine nucleoside phosphorylase-like [KO:K03783] [EC:2.4.2.1]
132779258  PNP; purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
132771347  LACC1; purine nucleoside phosphorylase LACC1 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
132762860  HPRT1; hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
132769454  IMPDH2; inosine-5'-monophosphate dehydrogenase 2 isoform X1 [KO:K00088] [EC:1.1.1.205]
132775592  IMPDH1; inosine-5'-monophosphate dehydrogenase 1 isoform X1 [KO:K00088] [EC:1.1.1.205]
132781784  NME4; nucleoside diphosphate kinase, mitochondrial [KO:K00940] [EC:2.7.4.6]
132781857  NME3; nucleoside diphosphate kinase 3 [KO:K00940] [EC:2.7.4.6]
132772045  NME7; nucleoside diphosphate kinase 7 isoform X1 [KO:K00940] [EC:2.7.4.6]
132768676  nucleoside diphosphate kinase A [KO:K00940] [EC:2.7.4.6]
132768677  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
132775605  NME6; nucleoside diphosphate kinase 6 [KO:K00940] [EC:2.7.4.6]
132760858  AK9; adenylate kinase 9 [KO:K18533] [EC:2.7.4.3 2.7.4.6]
132770832  ENTPD1; ectonucleoside triphosphate diphosphohydrolase 1 [KO:K01510] [EC:3.6.1.5]
132778649  ENTPD3; ectonucleoside triphosphate diphosphohydrolase 3 [KO:K01510] [EC:3.6.1.5]
132763935  ENTPD8; ectonucleoside triphosphate diphosphohydrolase 8 [KO:K01510] [EC:3.6.1.5]
132768453  CANT1; soluble calcium-activated nucleotidase 1 [KO:K12304] [EC:3.6.1.6]
132782587  ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4 isoform X1 [KO:K12305] [EC:3.6.1.6]
132764686  ENTPD5; nucleoside diphosphate phosphatase ENTPD5 isoform X1 [KO:K01511] [EC:3.6.1.6]
132761560  ENTPD6; ectonucleoside triphosphate diphosphohydrolase 6 [KO:K01511] [EC:3.6.1.6]
132767839  U8 snoRNA-decapping enzyme-like [KO:K16855] [EC:3.6.1.62 3.6.1.64]
132774339  ITPA; inosine triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
132761355  XDH; xanthine dehydrogenase/oxidase [KO:K00106] [EC:1.17.1.4 1.17.3.2]
132766823  NUDT2; bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] [KO:K01518] [EC:3.6.1.17]
132770569  GMPS; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
132777600  GMPR2; GMP reductase 2 [KO:K00364] [EC:1.7.1.7]
132774613  GMPR; GMP reductase 1 [KO:K00364] [EC:1.7.1.7]
132767353  GDA; guanine deaminase isoform X1 [KO:K01487] [EC:3.5.4.3]
132770303  RRM1; ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
132782774  RRM2; LOW QUALITY PROTEIN: ribonucleoside-diphosphate reductase subunit M2 [KO:K10808] [EC:1.17.4.1]
132775032  RRM2B; ribonucleoside-diphosphate reductase subunit M2 B [KO:K10808] [EC:1.17.4.1]
132760944  HDDC2; 5'-deoxynucleotidase HDDC2 [KO:K07023] [EC:3.1.3.89]
132782481  DGUOK; deoxyguanosine kinase, mitochondrial isoform X1 [KO:K00904] [EC:2.7.1.113]
132777081  DCK; deoxycytidine kinase [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
132768932  deoxycytidine kinase 2-like [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
132762453  HDDC3; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 [KO:K21138] [EC:3.1.7.2]
132764175  PRUNE1; exopolyphosphatase PRUNE1 isoform X1 [KO:K01514] [EC:3.6.1.11]
132778512  ADCY1; adenylate cyclase type 1 isoform X1 [KO:K08041] [EC:4.6.1.1]
132774200  ADCY2; adenylate cyclase type 2 [KO:K08042] [EC:4.6.1.1]
132761631  ADCY3; adenylate cyclase type 3 [KO:K08043] [EC:4.6.1.1]
132777697  ADCY4; adenylate cyclase type 4 isoform X1 [KO:K08044] [EC:4.6.1.1]
132774580  ADCY5; adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
132768345  ADCY6; adenylate cyclase type 6 [KO:K08046] [EC:4.6.1.1]
132783079  ADCY7; adenylate cyclase type 7 [KO:K08047] [EC:4.6.1.1]
132775114  ADCY8; adenylate cyclase type 8 isoform X1 [KO:K08048] [EC:4.6.1.1]
132782057  ADCY9; adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
132774317  ADCY10; adenylate cyclase type 10 [KO:K11265] [EC:4.6.1.1]
132776779  GUCY1A1; guanylate cyclase soluble subunit alpha-1 [KO:K12318] [EC:4.6.1.2]
132772185  GUCY1A2; guanylate cyclase soluble subunit alpha-2 [KO:K12318] [EC:4.6.1.2]
132770668  guanylate cyclase soluble subunit beta-2-like [KO:K12319] [EC:4.6.1.2]
132776780  GUCY1B1; guanylate cyclase soluble subunit beta-1 isoform X1 [KO:K12319] [EC:4.6.1.2]
132772237  guanylate cyclase soluble subunit beta-2-like [KO:K12319] [EC:4.6.1.2]
132775795  GUCY2C; guanylyl cyclase C [KO:K12320] [EC:4.6.1.2]
132777568  GUCY2D; retinal guanylyl cyclase 1 [KO:K12321] [EC:4.6.1.2]
132770285  retinal guanylyl cyclase 2-like [KO:K12322] [EC:4.6.1.2]
132770954  guanylate cyclase 2G-like [KO:K22600] [EC:4.6.1.2]
132764130  NPR1; atrial natriuretic peptide receptor 1 [KO:K12323] [EC:4.6.1.2]
132766793  NPR2; atrial natriuretic peptide receptor 2 [KO:K12324] [EC:4.6.1.2]
132767483  atrial natriuretic peptide receptor 2-like [KO:K12324] [EC:4.6.1.2]
132771788  dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A-like [KO:K13755] [EC:3.1.4.17]
132777677  PDE1A; dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X1 [KO:K13755] [EC:3.1.4.17]
132778569  PDE1C; dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform X1 [KO:K13755] [EC:3.1.4.17]
132768156  PDE1B; dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B isoform X1 [KO:K13755] [EC:3.1.4.17]
132772332  PDE2A; cGMP-dependent 3',5'-cyclic phosphodiesterase [KO:K18283] [EC:3.1.4.17]
132775736  PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A [KO:K19021] [EC:3.1.4.17]
132770500  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [KO:K13296] [EC:3.1.4.17]
132776889  PDE5A; cGMP-specific 3',5'-cyclic phosphodiesterase isoform X1 [KO:K13762] [EC:3.1.4.35]
132766571  PDE6B; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta [KO:K13756] [EC:3.1.4.35]
132771092  PDE6C; cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' [KO:K13757] [EC:3.1.4.35]
132770394  PDE6D; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta [KO:K13758]
132768420  PDE6G; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma [KO:K13759]
132776040  PDE6H; retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma [KO:K13760]
132771814  PDE9A; high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A isoform X1 [KO:K13761] [EC:3.1.4.35]
132761118  PDE10A; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1 [KO:K18438] [EC:3.1.4.17 3.1.4.35]
132777279  PDE11A; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A isoform X1 [KO:K13298] [EC:3.1.4.17 3.1.4.35]
132761225  ADSS2; adenylosuccinate synthetase isozyme 2 isoform X1 [KO:K01939] [EC:6.3.4.4]
132761586  ADSS1; adenylosuccinate synthetase isozyme 1 [KO:K01939] [EC:6.3.4.4]
132773341  AMPD1; AMP deaminase 1 isoform X1 [KO:K01490] [EC:3.5.4.6]
132773778  AMPD2; AMP deaminase 2 isoform X1 [KO:K01490] [EC:3.5.4.6]
132770087  AMPD3; AMP deaminase 3 isoform X1 [KO:K01490] [EC:3.5.4.6]
132771303  ADK; adenosine kinase [KO:K00856] [EC:2.7.1.20]
132773180  ADA; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
132775767  ADA2; adenosine deaminase 2 isoform X1 [KO:K19572] [EC:3.5.4.4]
132777308  adenylate kinase 8-like [KO:K00939] [EC:2.7.4.3]
132768067  adenylate kinase isoenzyme 1-like isoform X1 [KO:K00939] [EC:2.7.4.3]
132762715  AK7; adenylate kinase 7 [KO:K00939] [EC:2.7.4.3]
132774017  AK4; adenylate kinase 4, mitochondrial [KO:K00939] [EC:2.7.4.3]
132774061  AK5; adenylate kinase isoenzyme 5 [KO:K00939] [EC:2.7.4.3]
132780400  AK2; adenylate kinase 2, mitochondrial isoform X1 [KO:K00939] [EC:2.7.4.3]
132780402  adenylate kinase 2, mitochondrial isoform X1 [KO:K00939] [EC:2.7.4.3]
132763553  AK8; adenylate kinase 8 isoform X1 [KO:K00939] [EC:2.7.4.3]
132769727  adenylate kinase isoenzyme 1-like [KO:K00939] [EC:2.7.4.3]
132763956  AK1; adenylate kinase isoenzyme 1 [KO:K00939] [EC:2.7.4.3]
132767101  AK6; adenylate kinase isoenzyme 6 [KO:K18532] [EC:2.7.4.3]
132767393  AK3; GTP:AMP phosphotransferase AK3, mitochondrial [KO:K00944] [EC:2.7.4.10]
132763540  ectonucleoside triphosphate diphosphohydrolase 2-like [KO:K01509] [EC:3.6.1.-]
132761185  NTPCR; cancer-related nucleoside-triphosphatase isoform X1 [KO:K06928] [EC:3.6.1.15]
132760973  ENPP3; ectonucleotide pyrophosphatase/phosphodiesterase family member 3 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
132760974  ENPP1; ectonucleotide pyrophosphatase/phosphodiesterase family member 1 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
132767006  PDE4D; cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [KO:K13293] [EC:3.1.4.53]
132768047  PDE4A; cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X1 [KO:K13293] [EC:3.1.4.53]
132774022  PDE4B; cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [KO:K13293] [EC:3.1.4.53]
132780990  PDE4C; cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X1 [KO:K13293] [EC:3.1.4.53]
132760988  PDE7B; cAMP-specific 3',5'-cyclic phosphodiesterase 7B isoform X1 [KO:K18436] [EC:3.1.4.53]
132774883  PDE7A; high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A isoform X1 [KO:K18436] [EC:3.1.4.53]
132767055  PDE8B; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1 [KO:K18437] [EC:3.1.4.53]
132762711  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A-like [KO:K18437] [EC:3.1.4.53]
132769433  FHIT; bis(5'-adenosyl)-triphosphatase [KO:K01522] [EC:3.6.1.29]
132781250  bis(5'-adenosyl)-triphosphatase ENPP4-like [KO:K18424] [EC:3.6.1.29]
132771128  PAPSS2; bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 isoform X1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
132776939  PAPSS1; bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
132774080  uricase-like isoform X1 [KO:K00365] [EC:1.7.3.3]
132783023  5-hydroxyisourate hydrolase-like isoform X1 [KO:K07127] [EC:3.5.2.17]
132770780  allantoinase, mitochondrial-like [KO:K01466] [EC:3.5.2.5]
132782994  ALLC; probable inactive allantoicase [KO:K01477] [EC:3.5.3.4]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
asao00030  Pentose phosphate pathway
asao00220  Arginine biosynthesis
asao00250  Alanine, aspartate and glutamate metabolism
asao00260  Glycine, serine and threonine metabolism
asao00340  Histidine metabolism
asao00630  Glyoxylate and dicarboxylate metabolism
asao00730  Thiamine metabolism
asao00740  Riboflavin metabolism
asao00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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