KEGG   PATHWAY: bacu00230
Entry
bacu00230                   Pathway                                
Name
Purine metabolism - Balaenoptera acutorostrata scammoni (minke whale)
Class
Metabolism; Nucleotide metabolism
Pathway map
bacu00230  Purine metabolism
bacu00230

Module
bacu_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:bacu00230]
bacu_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:bacu00230]
bacu_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:bacu00230]
bacu_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:bacu00230]
bacu_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:bacu00230]
bacu_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:bacu00230]
bacu_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:bacu00230]
Other DBs
GO: 0006163 0042278
Organism
Balaenoptera acutorostrata scammoni (minke whale) [GN:bacu]
Gene
103007181  NUDT9; nudix hydrolase 9 [KO:K13988] [EC:3.6.1.13]
103010454  ADPRM; ADP-ribose/CDP-alcohol diphosphatase, manganese dependent [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
103014516  NUDT5; nudix hydrolase 5 [KO:K13987] [EC:3.6.1.13 3.6.1.58 2.7.7.96]
103004993  PGM1; phosphoglucomutase 1 [KO:K01835] [EC:5.4.2.2]
103005357  PGM2; phosphoglucomutase 2 [KO:K15779] [EC:5.4.2.2 5.4.2.7]
103012109  PRPS1; phosphoribosyl pyrophosphate synthetase 1 [KO:K00948] [EC:2.7.6.1]
103018942  PRPS2; phosphoribosyl pyrophosphate synthetase 2 [KO:K00948] [EC:2.7.6.1]
103008663  PPAT; phosphoribosyl pyrophosphate amidotransferase [KO:K00764] [EC:2.4.2.14]
102999179  GART; phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
103019154  PFAS; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
103009147  PAICS; phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01587] [EC:4.1.1.21 6.3.2.6]
103020170  ADSL; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
103007798  ATIC; 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
103007821  APRT; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
103015782  NT5C1A; 5'-nucleotidase, cytosolic IA [KO:K01081] [EC:3.1.3.5]
103005864  NT5C2; 5'-nucleotidase, cytosolic II [KO:K01081] [EC:3.1.3.5]
103013137  NT5M; 5',3'-nucleotidase, mitochondrial [KO:K01081] [EC:3.1.3.5]
103015036  NT5C1B; 5'-nucleotidase, cytosolic IB [KO:K01081] [EC:3.1.3.5]
103005468  NT5C; 5', 3'-nucleotidase, cytosolic [KO:K01081] [EC:3.1.3.5]
103003287  NT5E; 5'-nucleotidase ecto [KO:K19970] [EC:3.1.3.5]
103013357  PNP; purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
103004538  LACC1; laccase domain containing 1 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
102998133  HPRT1; hypoxanthine phosphoribosyltransferase 1 [KO:K00760] [EC:2.4.2.8]
102999243  hypoxanthine-guanine phosphoribosyltransferase-like [KO:K00760] [EC:2.4.2.8]
103018348  hypoxanthine-guanine phosphoribosyltransferase-like [KO:K00760] [EC:2.4.2.8]
103007759  IMPDH1; inosine monophosphate dehydrogenase 1 [KO:K00088] [EC:1.1.1.205]
103002959  IMPDH2; inosine monophosphate dehydrogenase 2 [KO:K00088] [EC:1.1.1.205]
103010493  NME3; NME/NM23 nucleoside diphosphate kinase 3 [KO:K00940] [EC:2.7.4.6]
103004420  NME4; NME/NM23 nucleoside diphosphate kinase 4 [KO:K00940] [EC:2.7.4.6]
103015517  NME6; NME/NM23 nucleoside diphosphate kinase 6 [KO:K00940] [EC:2.7.4.6]
103009098  NME7; NME/NM23 family member 7 [KO:K00940] [EC:2.7.4.6]
103010377  nucleoside diphosphate kinase A 1-like [KO:K00940] [EC:2.7.4.6]
103011051  NME2; NME/NM23 nucleoside diphosphate kinase 2 [KO:K00940] [EC:2.7.4.6]
103003253  AK9; adenylate kinase 9 [KO:K18533] [EC:2.7.4.3 2.7.4.6]
103006116  ENTPD8; ectonucleoside triphosphate diphosphohydrolase 8 [KO:K01510] [EC:3.6.1.5]
103014786  ENTPD1; ectonucleoside triphosphate diphosphohydrolase 1 [KO:K01510] [EC:3.6.1.5]
103018820  ENTPD3; ectonucleoside triphosphate diphosphohydrolase 3 [KO:K01510] [EC:3.6.1.5]
103016453  CANT1; calcium activated nucleotidase 1 [KO:K12304] [EC:3.6.1.6]
103001237  ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4 [KO:K12305] [EC:3.6.1.6]
103017331  ENTPD6; ectonucleoside triphosphate diphosphohydrolase 6 (putative) [KO:K01511] [EC:3.6.1.6]
103008563  ENTPD5; ectonucleoside triphosphate diphosphohydrolase 5 [KO:K01511] [EC:3.6.1.6]
103000667  NUDT16; nudix hydrolase 16 [KO:K16855] [EC:3.6.1.62 3.6.1.64]
103005908  ITPA; inosine triphosphatase [KO:K01519] [EC:3.6.1.66]
103004564  XDH; xanthine dehydrogenase [KO:K00106] [EC:1.17.1.4 1.17.3.2]
103006665  NUDT2; nudix hydrolase 2 [KO:K01518] [EC:3.6.1.17]
102997137  GMPS; guanine monophosphate synthase [KO:K01951] [EC:6.3.5.2]
103002306  GMPR2; guanosine monophosphate reductase 2 [KO:K00364] [EC:1.7.1.7]
103015298  GMPR; guanosine monophosphate reductase [KO:K00364] [EC:1.7.1.7]
103008849  GDA; guanine deaminase [KO:K01487] [EC:3.5.4.3]
102998186  GUK1; guanylate kinase 1 [KO:K00942] [EC:2.7.4.8]
103014342  RRM1; ribonucleotide reductase catalytic subunit M1 [KO:K10807] [EC:1.17.4.1]
103002730  RRM2; ribonucleotide reductase regulatory subunit M2 [KO:K10808] [EC:1.17.4.1]
103001800  RRM2B; ribonucleotide reductase regulatory TP53 inducible subunit M2B [KO:K10808] [EC:1.17.4.1]
103013952  HDDC2; HD domain containing 2 [KO:K07023] [EC:3.1.3.89]
102997266  DGUOK; deoxyguanosine kinase [KO:K00904] [EC:2.7.1.113]
103015268  DCK; deoxycytidine kinase [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
102998505  HDDC3; HD domain containing 3 [KO:K21138] [EC:3.1.7.2]
103011727  PRUNE1; prune exopolyphosphatase [KO:K01514] [EC:3.6.1.11]
102998650  ADCY1; adenylate cyclase 1 [KO:K08041] [EC:4.6.1.1]
103020085  ADCY2; adenylate cyclase 2 [KO:K08042] [EC:4.6.1.1]
103020845  ADCY3; adenylate cyclase 3 [KO:K08043] [EC:4.6.1.1]
103005549  ADCY4; adenylate cyclase 4 [KO:K08044] [EC:4.6.1.1]
103006764  ADCY5; adenylate cyclase 5 [KO:K08045] [EC:4.6.1.1]
103014094  ADCY6; adenylate cyclase 6 [KO:K08046] [EC:4.6.1.1]
102997912  ADCY7; adenylate cyclase 7 [KO:K08047] [EC:4.6.1.1]
103019172  ADCY8; adenylate cyclase 8 [KO:K08048] [EC:4.6.1.1]
103016058  ADCY9; adenylate cyclase 9 [KO:K08049] [EC:4.6.1.1]
103004098  ADCY10; adenylate cyclase 10, soluble [KO:K11265] [EC:4.6.1.1]
103012311  adenylate cyclase type 10-like [KO:K11265] [EC:4.6.1.1]
103007177  GUCY1A2; guanylate cyclase 1, soluble, alpha 2 [KO:K12318] [EC:4.6.1.2]
103020991  guanylate cyclase soluble subunit alpha-1-like [KO:K12318] [EC:4.6.1.2]
103020943  guanylate cyclase soluble subunit beta-2-like [KO:K12319] [EC:4.6.1.2]
103020709  GUCY1B3; guanylate cyclase 1 soluble subunit beta [KO:K12319] [EC:4.6.1.2]
103006662  GUCY2C; guanylate cyclase 2C [KO:K12320] [EC:4.6.1.2]
103016360  GUCY2D; guanylate cyclase 2D, retinal [KO:K12321] [EC:4.6.1.2]
103002685  olfactory guanylyl cyclase GC-D-like [KO:K12321] [EC:4.6.1.2]
102998599  GUCY2F; guanylate cyclase 2F, retinal [KO:K12322] [EC:4.6.1.2]
103006879  NPR1; natriuretic peptide receptor 1 [KO:K12323] [EC:4.6.1.2]
103002831  NPR2; natriuretic peptide receptor 2 [KO:K12324] [EC:4.6.1.2]
103015373  PDE1C; phosphodiesterase 1C [KO:K13755] [EC:3.1.4.17]
103007918  PDE1A; phosphodiesterase 1A [KO:K13755] [EC:3.1.4.17]
103006648  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B-like [KO:K13755] [EC:3.1.4.17]
103009980  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B-like [KO:K13755] [EC:3.1.4.17]
103005086  PDE1B; phosphodiesterase 1B [KO:K13755] [EC:3.1.4.17]
103008978  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B-like [KO:K13755] [EC:3.1.4.17]
103000616  PDE2A; phosphodiesterase 2A [KO:K18283] [EC:3.1.4.17]
103004781  PDE3A; phosphodiesterase 3A [KO:K19021] [EC:3.1.4.17]
103008332  PDE3B; phosphodiesterase 3B [KO:K13296] [EC:3.1.4.17]
102999225  PDE5A; phosphodiesterase 5A [KO:K13762] [EC:3.1.4.35]
103020829  PDE6A; phosphodiesterase 6A [KO:K08718] [EC:3.1.4.35]
103018123  PDE6B; phosphodiesterase 6B [KO:K13756] [EC:3.1.4.35]
102997447  PDE6C; phosphodiesterase 6C [KO:K13757] [EC:3.1.4.35]
103003324  PDE6D; phosphodiesterase 6D [KO:K13758]
103007298  PDE6G; phosphodiesterase 6G [KO:K13759]
103018198  PDE6H; phosphodiesterase 6H [KO:K13760]
103020659  PDE9A; phosphodiesterase 9A [KO:K13761] [EC:3.1.4.35]
103003425  PDE10A; phosphodiesterase 10A [KO:K18438] [EC:3.1.4.17 3.1.4.35]
103017485  PDE11A; phosphodiesterase 11A [KO:K13298] [EC:3.1.4.17 3.1.4.35]
103000380  ADSS; adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
103020390  ADSSL1; adenylosuccinate synthase like 1 [KO:K01939] [EC:6.3.4.4]
103005329  AMPD3; adenosine monophosphate deaminase 3 [KO:K01490] [EC:3.5.4.6]
103004634  AMPD1; adenosine monophosphate deaminase 1 [KO:K01490] [EC:3.5.4.6]
103007609  AMPD2; adenosine monophosphate deaminase 2 [KO:K01490] [EC:3.5.4.6]
103003336  ADK; adenosine kinase [KO:K00856] [EC:2.7.1.20]
103008126  ADA; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
103015304  CECR1; cat eye syndrome chromosome region, candidate 1 [KO:K19572] [EC:3.5.4.4]
103003133  AK4; adenylate kinase 4 [KO:K00939] [EC:2.7.4.3]
103007878  AK2; adenylate kinase 2 [KO:K00939] [EC:2.7.4.3]
103011319  AK8; adenylate kinase 8 [KO:K00939] [EC:2.7.4.3]
103011023  AK5; adenylate kinase 5 [KO:K00939] [EC:2.7.4.3]
103006652  AK1; adenylate kinase 1 [KO:K00939] [EC:2.7.4.3]
103012594  AK7; adenylate kinase 7 [KO:K00939] [EC:2.7.4.3]
103004393  adenylate kinase isoenzyme 6-like [KO:K18532] [EC:2.7.4.3]
103018485  AK3; adenylate kinase 3 [KO:K00944] [EC:2.7.4.10]
103013601  GTP:AMP phosphotransferase AK3, mitochondrial-like [KO:K00944] [EC:2.7.4.10]
103009045  ENTPD2; ectonucleoside triphosphate diphosphohydrolase 2 [KO:K01509] [EC:3.6.1.-]
103002536  NTPCR; nucleoside-triphosphatase, cancer-related [KO:K06928] [EC:3.6.1.15]
103007617  ENPP3; ectonucleotide pyrophosphatase/phosphodiesterase 3 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
103008111  ENPP1; ectonucleotide pyrophosphatase/phosphodiesterase 1 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
103017037  PDE4A; phosphodiesterase 4A [KO:K13293] [EC:3.1.4.53]
103000561  PDE4B; phosphodiesterase 4B [KO:K13293] [EC:3.1.4.53]
103008716  PDE4C; phosphodiesterase 4C [KO:K13293] [EC:3.1.4.53]
103002367  PDE4D; phosphodiesterase 4D [KO:K13293] [EC:3.1.4.53]
102999187  PDE7A; phosphodiesterase 7A [KO:K18436] [EC:3.1.4.53]
103020746  PDE7B; phosphodiesterase 7B [KO:K18436] [EC:3.1.4.53]
103004118  PDE8B; phosphodiesterase 8B [KO:K18437] [EC:3.1.4.53]
103013331  PDE8A; phosphodiesterase 8A [KO:K18437] [EC:3.1.4.53]
103003452  FHIT; fragile histidine triad [KO:K01522] [EC:3.6.1.29]
103013971  ENPP4; ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) [KO:K18424] [EC:3.6.1.29]
103019541  PAPSS1; 3'-phosphoadenosine 5'-phosphosulfate synthase 1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
102999911  PAPSS2; 3'-phosphoadenosine 5'-phosphosulfate synthase 2 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
103009966  uricase-like [KO:K00365] [EC:1.7.3.3]
102998311  5-hydroxyisourate hydrolase-like [KO:K07127] [EC:3.5.2.17]
103019206  ALLC; allantoicase [KO:K01477] [EC:3.5.3.4]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
bacu00030  Pentose phosphate pathway
bacu00220  Arginine biosynthesis
bacu00250  Alanine, aspartate and glutamate metabolism
bacu00260  Glycine, serine and threonine metabolism
bacu00340  Histidine metabolism
bacu00630  Glyoxylate and dicarboxylate metabolism
bacu00730  Thiamine metabolism
bacu00740  Riboflavin metabolism
bacu00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

DBGET integrated database retrieval system