KEGG   PATHWAY: smeo04310
Entry
smeo04310                   Pathway                                
Name
Wnt signaling pathway - Silurus meridionalis (southern catfish)
Description
Wnt proteins are secreted morphogens that are required for basic developmental processes, such as cell-fate specification, progenitor-cell proliferation and the control of asymmetric cell division, in many different species and organs. There are at least three different Wnt pathways: the canonical pathway, the planar cell polarity (PCP) pathway and the Wnt/Ca2+ pathway. In the canonical Wnt pathway, the major effect of Wnt ligand binding to its receptor is the stabilization of cytoplasmic beta-catenin through inhibition of the bea-catenin degradation complex. Beta-catenin is then free to enter the nucleus and activate Wnt-regulated genes through its interaction with TCF (T-cell factor) family transcription factors and concomitant recruitment of coactivators. Planar cell polarity (PCP) signaling leads to the activation of the small GTPases RHOA (RAS homologue gene-family member A) and RAC1, which activate the stress kinase JNK (Jun N-terminal kinase) and ROCK (RHO-associated coiled-coil-containing protein kinase 1) and leads to remodelling of the cytoskeleton and changes in cell adhesion and motility. WNT-Ca2+ signalling is mediated through G proteins and phospholipases and leads to transient increases in cytoplasmic free calcium that subsequently activate the kinase PKC (protein kinase C) and CAMKII (calcium calmodulin mediated kinase II) and the phosphatase calcineurin.
Class
Environmental Information Processing; Signal transduction
Pathway map
smeo04310  Wnt signaling pathway
smeo04310

Other DBs
GO: 0016055
Organism
Silurus meridionalis (southern catfish) [GN:smeo]
Gene
124399422  porcn; protein-serine O-palmitoleoyltransferase porcupine isoform X1 [KO:K00181] [EC:2.3.1.250]
124400532  porcnl; porcupine O-acyltransferase like [KO:K00181] [EC:2.3.1.250]
124400528  wnt2bb; wingless-type MMTV integration site family, member 2Bb [KO:K00182]
124395746  wnt2; protein Wnt-2 [KO:K00182]
124392559  wnt2ba; wingless-type MMTV integration site family, member 2Ba [KO:K00182]
124387156  wnt3a; protein Wnt-3a [KO:K00312]
124388610  wnt3; LOW QUALITY PROTEIN: proto-oncogene Wnt-3 [KO:K00312]
124402531  wnt4; protein Wnt-4a [KO:K00408]
124385190  wnt4b; wingless-type MMTV integration site family, member 4b [KO:K00408]
124400221  wnt5a; protein Wnt-5a [KO:K00444]
124401219  wnt5b; protein Wnt-5b [KO:K00444]
124383390  wnt6b; LOW QUALITY PROTEIN: protein Wnt-6 [KO:K00445]
124392807  wnt6a; protein Wnt-6 [KO:K00445]
124399008  protein Wnt-7a [KO:K00572]
124401198  wnt7ba; protein Wnt-7b [KO:K00572]
124402221  wnt7aa; wingless-type MMTV integration site family, member 7Aa [KO:K00572]
124392851  wnt7bb; protein Wnt-7b isoform X1 [KO:K00572]
124402112  wnt8b; protein Wnt-8b [KO:K00714]
124385671  wnt8a; protein Wnt-8a ORF1 [KO:K00714]
124386238  protein Wnt-8a ORF2 [KO:K00714]
124396321  wnt9b; protein Wnt-9b [KO:K01064]
124387155  wnt9a; protein Wnt-9a [KO:K01064]
124383363  wnt10a; protein Wnt-10a isoform X1 [KO:K01357]
124378951  wnt11f2; protein Wnt-11 isoform X1 [KO:K01384]
124393062  wnt11; protein Wnt-11 [KO:K01384]
124401547  wnt16; protein Wnt-16 [KO:K01558]
124378219  dand5; DAN domain family member 5 [KO:K01645]
124390798  notum1b; inactive palmitoleoyl-protein carboxylesterase notum1b [KO:K19882] [EC:3.1.1.98]
124392991  notum2; carboxylesterase notum2 [KO:K19882] [EC:3.1.1.98]
124400793  wif1; wnt inhibitory factor 1 [KO:K01691]
124389231  sost; sclerostin [KO:K16834]
124399232  dickkopf-related protein 4-like isoform X1 [KO:K02165]
124400130  dickkopf-related protein 4-like [KO:K02165]
124403007  dkk1a; dickkopf WNT signaling pathway inhibitor 1a [KO:K02165]
124394517  dkk2; dickkopf-related protein 2 [KO:K02165]
124388861  dkk1b; dickkopf-related protein 1b [KO:K02165]
124397516  serpinf1; pigment epithelium-derived factor [KO:K19614]
124380891  sfrp1a; secreted frizzled-related protein 1a [KO:K02166]
124393497  sfrp1b; secreted frizzled-related protein 1b [KO:K02166]
124394967  sfrp2l; LOW QUALITY PROTEIN: secreted frizzled-related protein 2-like [KO:K02176]
124381366  sfrp2; secreted frizzled-related protein 2 [KO:K02176]
124383231  frzb; secreted frizzled-related protein 3 [KO:K25481]
124394398  sfrp5; secreted frizzled-related protein 5 [KO:K02222]
124383880  rspo1; R-spondin-1 isoform X1 [KO:K19471]
124383870  rspo2; R-spondin-2 [KO:K23097]
124383869  rspo3; R-spondin-3 [KO:K23098]
124379855  lgr4; leucine-rich repeat-containing G-protein coupled receptor 4 [KO:K04309]
124401591  leucine-rich repeat-containing G-protein coupled receptor 5-like [KO:K04308]
124399077  leucine-rich repeat-containing G-protein coupled receptor 6 [KO:K08399]
124379386  E3 ubiquitin-protein ligase RNF43 isoform X1 [KO:K15694] [EC:2.3.2.27]
124380670  znrf3; E3 ubiquitin-protein ligase znrf3 [KO:K16273] [EC:2.3.2.27]
124383327  fzd7a; frizzled-7a [KO:K02432]
124392258  fzd7b; frizzled-7b [KO:K02432]
124396658  fzd2; frizzled-2 [KO:K02235]
124390284  fzd3b; frizzled-3b [KO:K02329]
124377039  fzd3a; frizzled-3a [KO:K02329]
124394917  fzd4; frizzled-4 [KO:K02354]
124383370  fzd5; frizzled-5 [KO:K02375]
124385250  fzd8a; frizzled-8a [KO:K02375]
124403889  fzd6; frizzled-6 [KO:K02376]
124399851  fzd10; frizzled-10 [KO:K02842]
124395352  fzd9b; frizzled-9b [KO:K02842]
124378773  fzd9a; frizzled-9 [KO:K02842]
124401196  lrp6; low-density lipoprotein receptor-related protein 6 [KO:K03068]
124386095  lrp5; low-density lipoprotein receptor-related protein 5 [KO:K03068]
124403003  bambib; BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) b [KO:K10162]
124388417  bambia; BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a [KO:K10162]
124403008  protein APCDD1-like isoform X1 [KO:K25812]
124385316  protein APCDD1-like [KO:K25812]
124388603  csnk1e; casein kinase I [KO:K08960] [EC:2.7.11.1]
124389781  ccdc88c; LOW QUALITY PROTEIN: protein Daple [KO:K25811]
124395469  segment polarity protein dishevelled homolog DVL-3 [KO:K02353]
124387750  dvl3a; segment polarity protein dishevelled homolog DVL-3a [KO:K02353]
124387764  dvl2; segment polarity protein dishevelled homolog DVL-2 [KO:K02353]
124383769  glycogen synthase kinase binding protein [KO:K03096]
124402311  csnk2a4; casein kinase II subunit alpha isoform X1 [KO:K03097] [EC:2.7.11.1]
124376250  zgc:86598; STKc_CK2_alpha domain-containing protein [KO:K03097] [EC:2.7.11.1]
124390928  csnk2a2a; casein kinase 2, alpha prime polypeptide a [KO:K03097] [EC:2.7.11.1]
124384029  csnk2a1; casein kinase II subunit alpha [KO:K03097] [EC:2.7.11.1]
124385905  csnk2a2b; casein kinase II subunit alpha' [KO:K03097] [EC:2.7.11.1]
124381936  csnk2b; casein kinase II subunit beta isoform X1 [KO:K03115]
124403704  nkd2b; protein naked cuticle homolog 2-like [KO:K03213]
124380122  nkd1; protein naked cuticle homolog 1 [KO:K03213]
124375948  naked cuticle-like protein 3 isoform X1 [KO:K03213]
124399045  CXXC-type zinc finger protein 4 [KO:K03344]
124394434  cxxc4; CXXC-type zinc finger protein 4 [KO:K03344]
124391497  senp2; sentrin-specific protease 2 [KO:K03345] [EC:3.4.22.68]
124383162  gsk3ba; glycogen synthase kinase-3 beta isoform X1 [KO:K03083] [EC:2.7.11.26]
124378012  gsk3bb; glycogen synthase kinase 3 beta, genome duplicate b isoform X1 [KO:K03083] [EC:2.7.11.26]
124396530  catenin beta-1-like [KO:K02105]
124384038  ctnnb1; catenin beta-1 isoform X1 [KO:K02105]
124375951  axin1; axin-1 isoform X1 [KO:K02157]
124377848  axin-1-like isoform X1 [KO:K02157]
124396832  axin2; axin-2 [KO:K04385]
124391979  axin-2-like [KO:K04385]
124391518  apc2; adenomatous polyposis coli protein 2 [KO:K02085]
124393273  apc; adenomatous polyposis coli protein [KO:K02085]
124386158  csnk1a1; casein kinase I isoform X1 [KO:K08957] [EC:2.7.11.1]
124397852  tcf7; transcription factor 7 isoform X1 [KO:K02620]
124399623  tcf7l1b; transcription factor 7-like 1-B [KO:K04490]
124388632  tcf7l2; transcription factor 7-like 2 isoform X1 [KO:K04491]
124377280  lef1; lymphoid enhancer-binding factor 1 isoform X1 [KO:K04492]
124388916  lzts2b; leucine zipper putative tumor suppressor 2 homolog isoform X1 [KO:K26471]
124403653  LOW QUALITY PROTEIN: leucine zipper putative tumor suppressor 2 homolog [KO:K26471]
124389108  protein chibby homolog 1-like [KO:K23402]
124389122  protein chibby homolog 1-like isoform X1 [KO:K23402]
124386870  chd8; chromodomain-helicase-DNA-binding protein 8 isoform X1 [KO:K04494] [EC:5.6.2.-]
124393259  ccar2; cell cycle and apoptosis regulator protein 2 [KO:K25816]
124376459  sirt1; NAD-dependent protein deacetylase sirtuin-1 [KO:K11411] [EC:2.3.1.286]
124386715  sox17; transcription factor SOX-17 [KO:K04495]
124390061  ctbp2a; C-terminal-binding protein 2a isoform X1 [KO:K04496] [EC:1.1.1.428]
124386316  C-terminal-binding protein 1 isoform X1 [KO:K04496] [EC:1.1.1.428]
124386346  C-terminal-binding protein 1 isoform X1 [KO:K04496] [EC:1.1.1.428]
124388862  ctbp2l; C-terminal binding protein 2, like [KO:K04496] [EC:1.1.1.428]
124395598  tle3a; transducin-like enhancer protein 3-A isoform X1 [KO:K04497]
124391015  tle2b; transducin-like enhancer protein 4 isoform X1 [KO:K04497]
124391121  tle2a; transducin-like enhancer protein 2a isoform X1 [KO:K04497]
124379708  tle3b; transducin-like enhancer protein 3-B isoform X1 [KO:K04497]
124375370  ctnnd2a; catenin delta-2 isoform X1 [KO:K23491]
124387302  ctnnd2b; catenin delta-2b isoform X1 [KO:K23491]
124396686  crebbpb; CREB binding protein b isoform X1 [KO:K04498] [EC:2.3.1.48]
124382004  ep300b; LOW QUALITY PROTEIN: histone acetyltransferase p300 [KO:K04498] [EC:2.3.1.48]
124379693  crebbpa; LOW QUALITY PROTEIN: CREB-binding protein [KO:K04498] [EC:2.3.1.48]
124389343  ep300a; histone acetyltransferase p300 isoform X1 [KO:K04498] [EC:2.3.1.48]
124389399  ruvbl1; ruvB-like 1 [KO:K04499] [EC:5.6.2.4]
124382125  smad10a; mothers against decapentaplegic homolog 4 isoform X1 [KO:K04501]
124384364  smad10b; mothers against decapentaplegic homolog 4 isoform X1 [KO:K04501]
124380660  smad4; mothers against decapentaplegic homolog 4 isoform X1 [KO:K04501]
124393756  smad4a; mothers against decapentaplegic homolog 4a isoform X1 [KO:K04501]
124395661  smad3b; mothers against decapentaplegic homolog 3b [KO:K23605]
124379665  smad3a; mothers against decapentaplegic homolog 3a [KO:K23605]
124401282  map3k7; mitogen-activated protein kinase kinase kinase 7 isoform X1 [KO:K04427] [EC:2.7.11.25]
124396719  nlk1; nemo-like kinase, type 1 [KO:K04468] [EC:2.7.11.24]
124394557  nlk2; serine/threonine-protein kinase NLK [KO:K04468] [EC:2.7.11.24]
124403655  myca; transcriptional regulator Myc-A [KO:K04377]
124387216  mycb; transcriptional regulator Myc-B [KO:K04377]
124377376  jun; transcription factor AP-1 [KO:K04448]
124387939  transcription factor AP-1-like [KO:K04448]
124378958  june; junE proto-oncogene, AP-1 transcription factor subunit [KO:K04448]
124391126  ccnd1; G1/S-specific cyclin-D1 [KO:K04503]
124400777  ccnd2b; G1/S-specific cyclin-D2b [KO:K10151]
124385932  ccnd2a; G1/S-specific cyclin-D2a [KO:K10151]
124377219  ccnd3; G1/S-specific cyclin-D3 [KO:K10152]
124375722  ccn4a; cellular communication network factor 4a [KO:K22471]
124385102  ccn4b; cellular communication network factor 4b [KO:K22471]
124399922  ppardb; peroxisome proliferator-activated receptor delta b [KO:K04504]
124390553  psen1; presenilin-1 [KO:K04505] [EC:3.4.23.-]
124376156  prkacaa; LOW QUALITY PROTEIN: protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a [KO:K04345] [EC:2.7.11.11]
124378405  prkacab; LOW QUALITY PROTEIN: cAMP-dependent protein kinase catalytic subunit alpha [KO:K04345] [EC:2.7.11.11]
124391230  prkacba; protein kinase, cAMP-dependent, catalytic, beta a isoform X1 [KO:K04345] [EC:2.7.11.11]
124387817  prkacbb; protein kinase, cAMP-dependent, catalytic, beta b isoform X1 [KO:K04345] [EC:2.7.11.11]
124379345  tp53; cellular tumor antigen p53 isoform X1 [KO:K04451]
124386843  cellular tumor antigen p53-like [KO:K04451]
124396254  siah1; E3 ubiquitin-protein ligase Siah1 isoform X1 [KO:K04506] [EC:2.3.2.27]
124386722  calcyclin-binding protein [KO:K04507]
124398234  skp1; S-phase kinase-associated protein 1 isoform X1 [KO:K03094]
124391056  tbl1xr1a; F-box-like/WD repeat-containing protein TBL1XR1a [KO:K04508]
124387788  F-box-like/WD repeat-containing protein TBL1XR1 [KO:K04508]
124392450  fbxw11a; F-box and WD repeat domain-containing 11-A isoform X1 [KO:K03362]
124393351  fbxw11b; F-box and WD repeat domain-containing 11-B isoform X1 [KO:K03362]
124403259  cul1a; cullin-1a [KO:K03347]
124403783  cul1b; LOW QUALITY PROTEIN: cullin-1b [KO:K03347]
124381909  rbx1; E3 ubiquitin-protein ligase RBX1 [KO:K03868] [EC:2.3.2.32]
124386254  gpc4; glypican-4 [KO:K08110]
124392973  ror1; inactive tyrosine-protein kinase transmembrane receptor ROR1 isoform X1 [KO:K05122] [EC:2.7.10.1]
124393145  ror2; tyrosine-protein kinase transmembrane receptor ROR2 isoform X1 [KO:K05123] [EC:2.7.10.1]
124402428  ryk; tyrosine-protein kinase RYK isoform X1 [KO:K05128] [EC:2.7.10.1]
124383220  vangl1; vang-like protein 1 [KO:K04510]
124377969  vang-like protein 1 [KO:K04510]
124387916  vangl2; vang-like protein 2 [KO:K04510]
124400075  prickle3; prickle planar cell polarity protein 3-B isoform X1 [KO:K04511]
124400478  prickle2a; prickle-like protein 2 isoform X1 [KO:K04511]
124402205  prickle2b; LOW QUALITY PROTEIN: prickle-like protein 2b [KO:K04511]
124392811  prickle1a; prickle-like protein 1a [KO:K04511]
124403831  invs; LOW QUALITY PROTEIN: inversin [KO:K19626]
124389718  daam2; LOW QUALITY PROTEIN: disheveled-associated activator of morphogenesis 2 [KO:K04512]
124390368  daam1a; disheveled-associated activator of morphogenesis 1-A [KO:K04512]
124376735  daam1b; disheveled-associated activator of morphogenesis 1b isoform X1 [KO:K04512]
124399042  rhoac; rho-related GTP-binding protein RhoA-C [KO:K04513]
124399789  rhoaa; rho-related GTP-binding protein RhoA-A [KO:K04513]
124400274  rhoab; rho-related GTP-binding protein RhoA-B [KO:K04513]
124400358  rhocb; rho-related GTP-binding protein RhoA-D [KO:K04513]
124402068  rho-related GTP-binding protein RhoA-B-like [KO:K04513]
124394107  rhoca; ras homolog family member Ca [KO:K04513]
124397095  rock2a; rho-associated protein kinase 2 isoform X1 [KO:K17388] [EC:2.7.11.1]
124400736  LOW QUALITY PROTEIN: rho-associated protein kinase 2-like [KO:K17388] [EC:2.7.11.1]
124397140  rac1b; ras-related C3 botulinum toxin substrate 1b [KO:K04392]
124389190  ras-related C3 botulinum toxin substrate 1-like isoform X1 [KO:K04392]
124397345  rac2; ras-related C3 botulinum toxin substrate 2 [KO:K07860]
124396730  rac3a; ras-related C3 botulinum toxin substrate 3a [KO:K07861]
124397718  mapk9; mitogen-activated protein kinase 9 [KO:K04440] [EC:2.7.11.24]
124397814  mapk10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
124396097  mapk8a; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
124388678  mapk8b; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
124389665  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 [KO:K05858] [EC:3.1.4.11]
124390133  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [KO:K05858] [EC:3.1.4.11]
124390267  plcb2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1 [KO:K05858] [EC:3.1.4.11]
124376730  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4-like isoform X1 [KO:K05858] [EC:3.1.4.11]
124376731  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [KO:K05858] [EC:3.1.4.11]
124386961  plcb3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1 [KO:K05858] [EC:3.1.4.11]
124397767  camk2a; calcium/calmodulin-dependent protein kinase type II subunit alpha [KO:K04515] [EC:2.7.11.17]
124375665  camk2g2; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1 [KO:K04515] [EC:2.7.11.17]
124386868  camk2d1; calcium/calmodulin-dependent protein kinase type II delta 1 chain isoform X1 [KO:K04515] [EC:2.7.11.17]
124380465  camk2b1; calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1 isoform X1 [KO:K04515] [EC:2.7.11.17]
124388818  camk2g1; calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1 isoform X1 [KO:K04515] [EC:2.7.11.17]
124393628  calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1 [KO:K04515] [EC:2.7.11.17]
124381399  camk2d2; LOW QUALITY PROTEIN: calcium/calmodulin-dependent protein kinase type II delta 2 chain [KO:K04515] [EC:2.7.11.17]
124398450  ppp3ca; serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
124386960  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
124392353  ppp3cb; serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
124393132  ppp3ccb; protein phosphatase 3, catalytic subunit, gamma isozyme, b isoform X1 [KO:K04348] [EC:3.1.3.16]
124381043  ppp3cca; protein phosphatase 3, catalytic subunit, gamma isozyme, a isoform X1 [KO:K04348] [EC:3.1.3.16]
124375269  ppp3r1a; LOW QUALITY PROTEIN: calcineurin subunit B type 1 [KO:K06268]
124378008  ppp3r1b; calcineurin subunit B type 1b isoform X1 [KO:K06268]
124397127  prkcab; protein kinase C alpha type isoform X1 [KO:K02677] [EC:2.7.11.13]
124392586  prkcaa; protein kinase C, alpha, a [KO:K02677] [EC:2.7.11.13]
124396752  prkcbb; protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
124378066  protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
124384840  prkcg; protein kinase C gamma type [KO:K19663] [EC:2.7.11.13]
124402962  nuclear factor of activated T-cells, cytoplasmic 1-like isoform X1 [KO:K04446]
124376117  nfatc1; nuclear factor of activated T-cells, cytoplasmic 1 isoform X1 [KO:K04446]
124399138  nfatc2a; nuclear factor of activated T-cells, cytoplasmic 2 isoform X1 [KO:K17332]
124385718  nuclear factor of activated T-cells, cytoplasmic 2 isoform X1 [KO:K17332]
124379689  nfatc3a; nuclear factor of activated T-cells, cytoplasmic 3 isoform X1 [KO:K17333]
124392637  nfatc3b; nuclear factor of activated T-cells, cytoplasmic 3 isoform X1 [KO:K17333]
124387604  nfatc4; nuclear factor of activated T-cells, cytoplasmic 4 [KO:K17334]
Compound
C00076  Calcium cation
Reference
PMID:14635791
  Authors
Hatsell S, Rowlands T, Hiremath M, Cowin P.
  Title
Beta-catenin and Tcfs in mammary development and cancer.
  Journal
J Mammary Gland Biol Neoplasia 8:145-58 (2003)
DOI:10.1023/A:1025944723047
Reference
PMID:14745971
  Authors
Yang Y.
  Title
Wnts and wing: Wnt signaling in vertebrate limb development and musculoskeletal morphogenesis.
  Journal
Birth Defects Res Part C Embryo Today 69:305-17 (2003)
DOI:10.1002/bdrc.10026
Reference
PMID:12446114
  Authors
Kalderon D.
  Title
Similarities between the Hedgehog and Wnt signaling pathways.
  Journal
Trends Cell Biol 12:523-31 (2002)
DOI:10.1016/S0962-8924(02)02388-7
Reference
PMID:14530294
  Authors
Nusse R.
  Title
Wnts and Hedgehogs: lipid-modified proteins and similarities in signaling mechanisms at the cell surface.
  Journal
Development 130:5297-305 (2003)
DOI:10.1242/dev.00821
Reference
PMID:15102436
  Authors
Jope RS, Johnson GV.
  Title
The glamour and gloom of glycogen synthase kinase-3.
  Journal
Trends Biochem Sci 29:95-102 (2004)
DOI:10.1016/j.tibs.2003.12.004
Reference
PMID:12967557
  Authors
Veeman MT, Axelrod JD, Moon RT.
  Title
A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling.
  Journal
Dev Cell 5:367-77 (2003)
DOI:10.1016/S1534-5807(03)00266-1
Reference
PMID:11433294
  Authors
Sun TQ, Lu B, Feng JJ, Reinhard C, Jan YN, Fantl WJ, Williams LT.
  Title
PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling.
  Journal
Nat Cell Biol 3:628-36 (2001)
DOI:10.1038/35083016
Reference
PMID:23256519
  Authors
Saito-Diaz K, Chen TW, Wang X, Thorne CA, Wallace HA, Page-McCaw A, Lee E
  Title
The way Wnt works: Components and mechanism.
  Journal
Growth Factors 31:1-31 (2013)
DOI:10.3109/08977194.2012.752737
Reference
PMID:19482104
  Authors
Carethers JM
  Title
Intersection of transforming growth factor-beta and Wnt signaling pathways in colorectal cancer and metastasis.
  Journal
Gastroenterology 137:33-6 (2009)
DOI:10.1053/j.gastro.2009.05.011
Reference
PMID:18838381
  Authors
Lin Z, Gao C, Ning Y, He X, Wu W, Chen YG
  Title
The pseudoreceptor BMP and activin membrane-bound inhibitor positively modulates Wnt/beta-catenin signaling.
  Journal
J Biol Chem 283:33053-8 (2008)
DOI:10.1074/jbc.M804039200
Reference
PMID:23151663
  Authors
Niehrs C
  Title
The complex world of WNT receptor signalling.
  Journal
Nat Rev Mol Cell Biol 13:767-79 (2012)
DOI:10.1038/nrm3470
Reference
PMID:28522145
  Authors
Abou Ziki MD, Mani A
  Title
Wnt signaling, a novel pathway regulating blood pressure? State of the art review.
  Journal
Atherosclerosis 262:171-178 (2017)
DOI:10.1016/j.atherosclerosis.2017.05.001
Reference
PMID:25808920
  Authors
He Y, Ki H, Kim H, Kim K
  Title
delta-Catenin interacts with LEF-1 and negatively regulates its transcriptional activity.
  Journal
Cell Biol Int 39:954-61 (2015)
DOI:10.1002/cbin.10465
Reference
PMID:32888647
  Authors
Esaki N, Enomoto A, Takagishi M, Mizutani Y, Iida T, Ushida K, Shiraki Y, Mii S, Takahashi M
  Title
The Daple-CK1epsilon complex regulates Dvl2 phosphorylation and canonical Wnt signaling.
  Journal
Biochem Biophys Res Commun 532:406-413 (2020)
DOI:10.1016/j.bbrc.2020.08.066
Reference
PMID:28242765
  Authors
Yiew NKH, Chatterjee TK, Tang YL, Pellenberg R, Stansfield BK, Bagi Z, Fulton DJ, Stepp DW, Chen W, Patel V, Kamath VM, Litwin SE, Hui DY, Rudich SM, Kim HW, Weintraub NL
  Title
A novel role for the Wnt inhibitor APCDD1 in adipocyte differentiation: Implications for diet-induced obesity.
  Journal
J Biol Chem 292:6312-6324 (2017)
DOI:10.1074/jbc.M116.758078
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