KEGG Orthology (KO) - Escherichia coli O145:H28 RM13516 (EHEC)

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     KO
 09100 Metabolism
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
 09140 Cellular Processes
 
   09141 Transport and catabolism
 
   09143 Cell growth and death
 
   09144 Cellular community - eukaryotes
 
   09145 Cellular community - prokaryotes
     02024 Quorum sensing [PATH:ecoh02024]
       ECRM13516_3397 luxS; S-ribosylhomocysteine lyase / Autoinducer-2 production protein LuxS
       ECRM13516_5175 hfq; RNA-binding protein Hfq
       ECRM13516_1648 trpE; Anthranilate synthase, aminase component
       ECRM13516_2106 aroH; 2-keto-3-deoxy-D-arabino-heptulosonate-7-phosphate synthase I alpha
       ECRM13516_3283 aroF; 2-keto-3-deoxy-D-arabino-heptulosonate-7-phosphate synthase I alpha
       ECRM13516_0724 aroG; 2-keto-3-deoxy-D-arabino-heptulosonate-7-phosphate synthase I alpha
       ECRM13516_3795 qseC; Sensory histidine kinase QseC
       ECRM13516_3794 qseB; Two-component system response regulator QseB
       ECRM13516_3239 yfhK; Putative sensor-like histidine kinase YfhK
       ECRM13516_3237 yfhA; Putative sensory histidine kinase YfhA
       ECRM13516_2366 flhD; Flagellar transcriptional activator FlhD
       ECRM13516_2365 flhC; Flagellar transcriptional activator FlhC
       ECRM13516_2316 stx2A; Shiga-like toxin II subunit A precursor
       ECRM13516_2315 stx2B; Shiga-like toxin II subunit B precursor
       ECRM13516_1074 tccP; T3SS secreted effector TccP
       ECRM13516_0659 kdpE; DNA-binding response regulator KdpE
       ECRM13516_0342 Sensor histidine protein kinase UhpB
       ECRM13516_0343 Transcriptional regulatory protein UhpA
       ECRM13516_4502 Ler protein
       ECRM13516_2402 sdiA; N-3-oxohexanoyl-L-homoserine lactone quorum-sensing transcriptional activator SdiA
       ECRM13516_4305 gadA; Glutamate decarboxylase
       ECRM13516_1857 gadB; Glutamate decarboxylase
       ECRM13516_1856 xasA; putative glutamate/gamma-aminobutyrate antiporter
       ECRM13516_1881 lsrB; Autoinducer 2 (AI-2) ABC transport system, periplasmic AI-2 binding protein LsrB
       ECRM13516_1879 lsrC; Autoinducer 2 (AI-2) ABC transport system, membrane channel protein LsrC
       ECRM13516_1880 lsrD; Autoinducer 2 (AI-2) ABC transport system, membrane channel protein LsrD
       ECRM13516_1878 Autoinducer 2 (AI-2) ABC transport system
       ECRM13516_1876 lsrK; Autoinducer 2 (AI-2) kinase LsrK
       ECRM13516_1877 lsrR; LsrR, transcriptional repressor of lsr operon
       ECRM13516_1882 lsrF; Autoinducer 2 (AI-2) aldolase LsrF
       ECRM13516_1883 lsrG; Autoinducer 2 (AI-2) modifying protein LsrG
       ECRM13516_1798 ABC transporter
       ECRM13516_1801 ABC transporter permease component
       ECRM13516_1800 ABC transporter permease component
       ECRM13516_1799 Transport ATP-binding protein
       ECRM13516_4207 livK; High-affinity leucine-specific transport system, periplasmic binding protein LivK
       ECRM13516_4212 livJ; Branched-chain amino acid ABC transporter, amino acid-binding protein
       ECRM13516_4206 livH; High-affinity branched-chain amino acid transport system permease protein LivH
       ECRM13516_4205 livM; Branched-chain amino acid transport system permease protein LivM
       ECRM13516_4204 livG; Branched-chain amino acid transport ATP-binding protein LivG
       ECRM13516_4203 livF; Branched-chain amino acid transport ATP-binding protein LivF
       ECRM13516_2435 rcsA; Colanic acid capsular biosynthesis activation accesory protein RcsA, co-regulator with RcsB
       ECRM13516_1672 yciR; RNase II stability modulator
       ECRM13516_2210 fadD; Long-chain-fatty-acid--CoA ligase
       ECRM13516_4101 crp; Cyclic AMP receptor protein
       ECRM13516_4918 yjbK; Zinc uptake regulation protein ZUR
       ECRM13516_1663 ribA; GTP cyclohydrolase II
       ECRM13516_0396 ribD; Diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase
       ECRM13516_2559 Putative inner membrane protein
       ECRM13516_1805 Putative inner membrane protein
       ECRM13516_1679 cmeC; RND efflux system, outer membrane lipoprotein CmeC
       ECRM13516_1725 mppA; Periplasmic Murein Peptide-Binding Protein MppA
       ECRM13516_1570 oppA; Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA
       ECRM13516_1571 oppB; Oligopeptide transport system permease protein OppB
       ECRM13516_1572 oppC; Oligopeptide transport system permease protein OppC
       ECRM13516_1573 oppD; Oligopeptide transport ATP-binding protein OppD
       ECRM13516_1574 oppF; Oligopeptide transport ATP-binding protein OppF
       ECRM13516_3789 oppA_2; Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA
       ECRM13516_1851 Dipeptide-binding ABC transporter; Putative hemin-binding lipoprotein
       ECRM13516_1850 dppB; Dipeptide transport system permease protein DppB; putative hemin permease
       ECRM13516_1849 dppC; Dipeptide transport system permease protein DppC; Putative hemine transporter ATP-binding subunit
       ECRM13516_1848 dppD; Dipeptide transport system permease protein DppD; Putative hemine transporter ATP-binding subunit
       ECRM13516_1847 dppF; Dipeptide transport ATP-binding protein DppF
       ECRM13516_4555 yidC; Inner membrane protein translocase component YidC, long form
       ECRM13516_4837 secE; Preprotein translocase subunit SecE
       ECRM13516_3938 secG; Preprotein translocase subunit SecG
       ECRM13516_4057 secY; Preprotein translocase secY subunit
       ECRM13516_0389 yajC; Preprotein translocase subunit YajC
       ECRM13516_0105 secA; Protein export cytoplasm protein SecA ATPase RNA helicase
       ECRM13516_4216 ftsY; Signal recognition particle receptor protein FtsY (alpha subunit)
       ECRM13516_4399 secB; Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state)
       ECRM13516_3292 ffh; Signal recognition particle, subunit Ffh
K07173 luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21]
K03666 hfq; host factor-I protein
K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]
K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]
K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]
K07645 qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3]
K07666 qseB; two-component system, OmpR family, response regulator QseB
K07711 glrK; two-component system, NtrC family, sensor histidine kinase GlrK [EC:2.7.13.3]
K07715 glrR; two-component system, NtrC family, response regulator GlrR
K02403 flhD; flagellar transcriptional activator FlhD
K02402 flhC; flagellar transcriptional activator FlhC
K11006 stxA; shiga toxin subunit A
K11007 stxB; shiga toxin subunit B
K12789 tccP; Tir-cytoskeleton coupling protein
K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
K20263 fusK; two-component system, NarL family, sensor histidine kinase FusK [EC:2.7.13.3]
K20264 fusR; two-component system, NarL family, response regulator FusR
K20552 ler; transcriptional regulator of LEE operons
K07782 sdiA; LuxR family transcriptional regulator, quorum-sensing system regulator SdiA
K01580 E4.1.1.15; glutamate decarboxylase [EC:4.1.1.15]
K01580 E4.1.1.15; glutamate decarboxylase [EC:4.1.1.15]
K20265 gadC; glutamate:GABA antiporter
K10555 lsrB; AI-2 transport system substrate-binding protein
K10556 lsrC; AI-2 transport system permease protein
K10557 lsrD; AI-2 transport system permease protein
K10558 lsrA; AI-2 transport system ATP-binding protein
K11216 lsrK; autoinducer-2 kinase [EC:2.7.1.189]
K11531 lsrR; lsr operon transcriptional repressor
K08321 lsrF; 3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase [EC:2.3.1.245]
K11530 lsrG; (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase [EC:5.3.1.32]
K02055 ABC.SP.S; putative spermidine/putrescine transport system substrate-binding protein
K02053 ABC.SP.P; putative spermidine/putrescine transport system permease protein
K02054 ABC.SP.P1; putative spermidine/putrescine transport system permease protein
K02052 ABC.SP.A; putative spermidine/putrescine transport system ATP-binding protein
K01999 livK; branched-chain amino acid transport system substrate-binding protein
K01999 livK; branched-chain amino acid transport system substrate-binding protein
K01997 livH; branched-chain amino acid transport system permease protein
K01998 livM; branched-chain amino acid transport system permease protein
K01995 livG; branched-chain amino acid transport system ATP-binding protein
K01996 livF; branched-chain amino acid transport system ATP-binding protein
K07781 rcsA; LuxR family transcriptional regulator, capsular biosynthesis positive transcription factor
K14051 gmr; c-di-GMP phosphodiesterase Gmr [EC:3.1.4.52]
K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein
K09823 zur; Fur family transcriptional regulator, zinc uptake regulator
K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25]
K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]
K09936 TC.BAT2; bacterial/archaeal transporter family-2 protein
K09936 TC.BAT2; bacterial/archaeal transporter family-2 protein
K18139 oprM; outer membrane protein, multidrug efflux system
K15580 oppA; oligopeptide transport system substrate-binding protein
K15580 oppA; oligopeptide transport system substrate-binding protein
K15581 oppB; oligopeptide transport system permease protein
K15582 oppC; oligopeptide transport system permease protein
K15583 oppD; oligopeptide transport system ATP-binding protein
K10823 oppF; oligopeptide transport system ATP-binding protein
K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
K02033 ABC.PE.P; peptide/nickel transport system permease protein
K02034 ABC.PE.P1; peptide/nickel transport system permease protein
K02031 ddpD; peptide/nickel transport system ATP-binding protein
K02032 ddpF; peptide/nickel transport system ATP-binding protein
K03217 yidC; YidC/Oxa1 family membrane protein insertase
K03073 secE; preprotein translocase subunit SecE
K03075 secG; preprotein translocase subunit SecG
K03076 secY; preprotein translocase subunit SecY
K03210 yajC; preprotein translocase subunit YajC
K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
K03110 ftsY; fused signal recognition particle receptor
K03071 secB; preprotein translocase subunit SecB
K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
     05111 Biofilm formation - Vibrio cholerae
     02025 Biofilm formation - Pseudomonas aeruginosa
     02026 Biofilm formation - Escherichia coli [PATH:ecoh02026]
 
   09142 Cell motility
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
   09161 Cancer: overview
 
   09162 Cancer: specific types
 
   09163 Immune disease
 
   09164 Neurodegenerative disease
 
   09165 Substance dependence
 
   09166 Cardiovascular disease
 
   09167 Endocrine and metabolic disease
 
   09171 Infectious disease: bacterial
     05110 Vibrio cholerae infection
     05120 Epithelial cell signaling in Helicobacter pylori infection
     05130 Pathogenic Escherichia coli infection [PATH:ecoh05130]
       ECRM13516_2316 stx2A; Shiga-like toxin II subunit A precursor
       ECRM13516_2315 stx2B; Shiga-like toxin II subunit B precursor
       ECRM13516_0802 espJ; T3SS effector protein EspJ
       ECRM13516_4503 espG; T3SS secreted effector protein EspG
       ECRM13516_4481 espH; EspH
       ECRM13516_4471 espB; T3SS secreted effector protein EspB
       ECRM13516_4479 map_2; T3SS secreted effector protein Map
       ECRM13516_1636 espM; T3SS secreted effector protein EspM
       ECRM13516_4476 eae; intimin adherence protein
       ECRM13516_4478 tir; translocated intimin receptor Tir
       ECRM13516_1074 tccP; T3SS secreted effector TccP
       ECRM13516_1778 gapC; NAD-dependent glyceraldehyde-3-phosphate dehydrogenase
       ECRM13516_2183 gapA; NAD-dependent glyceraldehyde-3-phosphate dehydrogenase
       ECRM13516_5228 nleE; T3SS secreted effector protein NleE
       ECRM13516_0797 nleH; T3SS secreted effector NleH
       ECRM13516_2458 nleH_2; T3SS secreted effector protein NleH
       ECRM13516_1911 nleC; T3SS secreted effector protein NleC
       ECRM13516_2281 nleC_2; T3SS secreted effector protein NleC
       ECRM13516_5227 nleB_3; T3SS secreted effector protein NleB
       ECRM13516_2459 nleB_2; T3SS secreted effector protein NleB
       ECRM13516_2457 nleF; T3SS secreted effector protein NleF
       ECRM13516_4487 espZ; T3SS secreted effector protein EspZ
       ECRM13516_0799 cif; Cell Inhibiting Factor (Cif)
       ECRM13516_4467 espF; T3SS secreted effector protein EspF
       ECRM13516_4469 ssaG; Type III secretion protein SsaG
       ECRM13516_2757 nleA; T3SS secreted effector protein NleA
K11006 stxA; shiga toxin subunit A
K11007 stxB; shiga toxin subunit B
K23648 espJ; T3SS secreted effector ADP-ribosyltransferase EspJ
K12785 espG; LEE-encoded effector EspG
K12788 espH; LEE-encoded effector EspH
K23650 espB; LEE-encoded effector EspB
K12787 map; LEE-encoded effector Map
K23653 espM; T3SS effector EspM
K12790 eae; intimin
K12784 tir; translocated intimin receptor
K12789 tccP; Tir-cytoskeleton coupling protein
K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12]
K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12]
K23654 nleE; T3SS secreted effector NleE
K16042 nleH; non-LEE-encoded effector NleH
K16042 nleH; non-LEE-encoded effector NleH
K23655 nleC; T3SS secreted effector NleC
K23655 nleC; T3SS secreted effector NleC
K23657 nleB; T3SS secreted effector NleB
K23657 nleB; T3SS secreted effector NleB
K23658 nleF; T3SS secreted effector NleF
K23659 espZ; LEE-encoded effector EspZ
K23660 cif; cell inhibiting factor
K12786 espF; LEE-encoded effector EspF
K03221 yscF; type III secretion protein F
K16041 nleA; non-LEE-encoded effector NleA
     05132 Salmonella infection
     05131 Shigellosis
     05135 Yersinia infection
     05133 Pertussis
     05134 Legionellosis
     05150 Staphylococcus aureus infection
     05152 Tuberculosis
     05100 Bacterial invasion of epithelial cells
 
   09172 Infectious disease: viral
 
   09174 Infectious disease: parasitic
 
   09175 Drug resistance: antimicrobial
 
   09176 Drug resistance: antineoplastic
 
 09180 Brite Hierarchies
 
   09181 Protein families: metabolism
 
   09182 Protein families: genetic information processing
 
   09183 Protein families: signaling and cellular processes
     02000 Transporters [BR:ecoh02000]
     02044 Secretion system [BR:ecoh02044]
     02042 Bacterial toxins [BR:ecoh02042]
       ECRM13516_2316 stx2A; Shiga-like toxin II subunit A precursor
       ECRM13516_2315 stx2B; Shiga-like toxin II subunit B precursor
       ECRM13516_5548 hlyA; hemolysin A
       ECRM13516_3619 oxidoreductase
       ECRM13516_1492 hlyE; Hemolysin E, chromosomal
K11006 stxA; shiga toxin subunit A
K11007 stxB; shiga toxin subunit B
K11005 hlyA; hemolysin A
K11068 hlyIII; hemolysin III
K11139 hlyE; hemolysin E
     02022 Two-component system [BR:ecoh02022]
     02035 Bacterial motility proteins [BR:ecoh02035]
     04812 Cytoskeleton proteins [BR:ecoh04812]
     04147 Exosome [BR:ecoh04147]
     02048 Prokaryotic defense system [BR:ecoh02048]
     04030 G protein-coupled receptors
     04050 Cytokine receptors
     04054 Pattern recognition receptors
     03310 Nuclear receptors
     04040 Ion channels
     04031 GTP-binding proteins
     04052 Cytokines and growth factors
     04515 Cell adhesion molecules
     04090 CD molecules [BR:ecoh04090]
     00535 Proteoglycans
     00536 Glycosaminoglycan binding proteins
     00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:ecoh00537]
     04091 Lectins
     01504 Antimicrobial resistance genes [BR:ecoh01504]
     03200 Viral proteins
     03210 Viral fusion proteins
     04990 Domain-containing proteins not elsewhere classified
 
   09184 RNA family
 
 09190 Not Included in Pathway or Brite

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Last updated: January 25, 2021