KEGG   PATHWAY: cclu04070
Entry
cclu04070                   Pathway                                
Name
Phosphatidylinositol signaling system - Coregonus clupeaformis (lake whitefish)
Class
Environmental Information Processing; Signal transduction
Pathway map
cclu04070  Phosphatidylinositol signaling system
cclu04070

Organism
Coregonus clupeaformis (lake whitefish) [GN:cclu]
Gene
121530693  [KO:K00981] [EC:2.7.7.41]
121531549  pik3c2g; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma [KO:K00923] [EC:2.7.1.154]
121531550  [KO:K05861] [EC:3.1.4.11]
121532078  [KO:K00923] [EC:2.7.1.154]
121532098  dgkzb; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
121532106  [KO:K02183]
121532110  [KO:K15909] [EC:3.1.3.86]
121532116  [KO:K13024] [EC:2.7.4.24]
121532117  [KO:K00915] [EC:2.7.1.140 2.7.1.151]
121532247  [KO:K04959]
121532409  [KO:K00901] [EC:2.7.1.107]
121533158  [KO:K02677] [EC:2.7.11.13]
121533376  [KO:K00922] [EC:2.7.1.153]
121533385  [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
121533582  [KO:K00889] [EC:2.7.1.68]
121533661  [KO:K02649]
121533863  [KO:K01116] [EC:3.1.4.11]
121533992  [KO:K00920] [EC:2.7.1.149]
121534059  [KO:K02649]
121534172  [KO:K03084] [EC:3.1.3.86]
121534223  [KO:K01109] [EC:3.1.3.66]
121534627  [KO:K05860] [EC:3.1.4.11]
121534682  [KO:K13084] [EC:3.1.3.78]
121534970  [KO:K00922] [EC:2.7.1.153]
121535055  [KO:K02649]
121535119  [KO:K15759] [EC:3.1.3.7]
121535176  ocrl; inositol polyphosphate 5-phosphatase OCRL isoform X1 [KO:K01099] [EC:3.1.3.36]
121535385  plcd1b; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1b isoform X1 [KO:K05857] [EC:3.1.4.11]
121535583  [KO:K02649]
121535671  [KO:K00889] [EC:2.7.1.68]
121535994  [KO:K01109] [EC:3.1.3.66]
121536485  [KO:K00901] [EC:2.7.1.107]
121536655  [KO:K05857] [EC:3.1.4.11]
121537033  [KO:K00901] [EC:2.7.1.107]
121537047  [KO:K00921] [EC:2.7.1.150]
121537628  inpp5d; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1 [KO:K03084] [EC:3.1.3.86]
121537932  [KO:K00920] [EC:2.7.1.149]
121538033  [KO:K00901] [EC:2.7.1.107]
121538342  [KO:K04960]
121538393  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
121539140  [KO:K00911] [EC:2.7.1.127]
121539329  [KO:K00913] [EC:2.7.1.159 2.7.1.134]
121539477  [KO:K02183]
121540427  [KO:K02649]
121540443  [KO:K01099] [EC:3.1.3.36]
121540715  [KO:K00923] [EC:2.7.1.154]
121540808  [KO:K13024] [EC:2.7.4.24]
121541581  [KO:K02649]
121541642  [KO:K00889] [EC:2.7.1.68]
121541829  [KO:K02183]
121542027  synj1; LOW QUALITY PROTEIN: synaptojanin-1 [KO:K20279] [EC:3.1.3.36]
121542694  [KO:K00889] [EC:2.7.1.68]
121543002  [KO:K15909] [EC:3.1.3.86]
121543015  [KO:K21797] [EC:3.1.3.-]
121543214  [KO:K00889] [EC:2.7.1.68]
121543670  [KO:K00901] [EC:2.7.1.107]
121543837  [KO:K19663] [EC:2.7.11.13]
121543900  [KO:K19801] [EC:2.7.1.67]
121544287  [KO:K05858] [EC:3.1.4.11]
121544381  [KO:K05858] [EC:3.1.4.11]
121544751  [KO:K02183]
121544863  [KO:K00913] [EC:2.7.1.159 2.7.1.134]
121545055  [KO:K00911] [EC:2.7.1.127]
121545718  [KO:K00901] [EC:2.7.1.107]
121545817  pip4k2ca; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma [KO:K00920] [EC:2.7.1.149]
121546039  [KO:K04960]
121546104  plcg1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1 [KO:K01116] [EC:3.1.4.11]
121546233  [KO:K00901] [EC:2.7.1.107]
121546669  [KO:K00901] [EC:2.7.1.107]
121547314  [KO:K05860] [EC:3.1.4.11]
121547337  [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
121547349  [KO:K00915] [EC:2.7.1.140 2.7.1.151]
121547923  [KO:K13711] [EC:2.7.1.67]
121548165  [KO:K02183]
121548501  [KO:K02183]
121548687  [KO:K05858] [EC:3.1.4.11]
121548707  [KO:K05858] [EC:3.1.4.11]
121548905  [KO:K00911] [EC:2.7.1.127]
121549409  plcd1a; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1a isoform X1 [KO:K05857] [EC:3.1.4.11]
121549675  [KO:K01092] [EC:3.1.3.25]
121549754  [KO:K18083] [EC:3.1.3.64 3.1.3.95]
121549782  pip4k2aa; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1 [KO:K00920] [EC:2.7.1.149]
121550061  [KO:K01092] [EC:3.1.3.25]
121550356  [KO:K00999] [EC:2.7.8.11]
121551406  plcd4b; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X1 [KO:K05857] [EC:3.1.4.11]
121551465  [KO:K02677] [EC:2.7.11.13]
121551593  [KO:K20278] [EC:3.1.3.36]
121551917  [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
121552067  [KO:K02183]
121552187  [KO:K05858] [EC:3.1.4.11]
121552366  [KO:K00911] [EC:2.7.1.127]
121552683  [KO:K05858] [EC:3.1.4.11]
121552857  itpk1a; inositol-tetrakisphosphate 1-kinase isoform X1 [KO:K00913] [EC:2.7.1.159 2.7.1.134]
121553248  [KO:K05860] [EC:3.1.4.11]
121553490  [KO:K01106] [EC:3.1.3.56]
121553593  calm2a; calmodulin 2a (phosphorylase kinase, delta) [KO:K02183]
121553603  inpp5f; phosphatidylinositide phosphatase SAC2 [KO:K21798] [EC:3.1.3.-]
121553788  [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
121554225  [KO:K00901] [EC:2.7.1.107]
121554349  [KO:K05858] [EC:3.1.4.11]
121554639  [KO:K01109] [EC:3.1.3.66]
121554719  [KO:K18081] [EC:3.1.3.64 3.1.3.95]
121554723  [KO:K01108] [EC:3.1.3.64 3.1.3.95]
121554851  dgkh; diacylglycerol kinase eta isoform X1 [KO:K00901] [EC:2.7.1.107]
121554984  [KO:K00921] [EC:2.7.1.150]
121555146  [KO:K00901] [EC:2.7.1.107]
121556450  [KO:K05857] [EC:3.1.4.11]
121556473  [KO:K19663] [EC:2.7.11.13]
121556603  [KO:K10572] [EC:2.7.1.158]
121557030  [KO:K19662] [EC:2.7.11.13]
121557105  prkcab; protein kinase C alpha type [KO:K02677] [EC:2.7.11.13]
121557873  zgc:158659; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
121559874  [KO:K05858] [EC:3.1.4.11]
121559957  [KO:K00901] [EC:2.7.1.107]
121560294  pi4k2a; phosphatidylinositol 4-kinase type 2-alpha [KO:K13711] [EC:2.7.1.67]
121560363  [KO:K02183]
121560626  [KO:K00911] [EC:2.7.1.127]
121561504  [KO:K00901] [EC:2.7.1.107]
121561893  [KO:K19662] [EC:2.7.11.13]
121561928  [KO:K00901] [EC:2.7.1.107]
121562447  [KO:K19801] [EC:2.7.1.67]
121562493  [KO:K00901] [EC:2.7.1.107]
121562532  [KO:K13711] [EC:2.7.1.67]
121563265  dgke; LOW QUALITY PROTEIN: diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
121563896  [KO:K00913] [EC:2.7.1.159 2.7.1.134]
121564394  [KO:K19801] [EC:2.7.1.67]
121564745  plcd3b; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3-A [KO:K05857] [EC:3.1.4.11]
121564833  mtmr7b; myotubularin-related protein 7b isoform X1 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
121566343  [KO:K19801] [EC:2.7.1.67]
121566622  [KO:K18086] [EC:3.1.3.64 3.1.3.95]
121566800  inppl1a; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2A [KO:K15909] [EC:3.1.3.86]
121566901  [KO:K00922] [EC:2.7.1.153]
121567283  [KO:K00901] [EC:2.7.1.107]
121567367  [KO:K00911] [EC:2.7.1.127]
121567381  [KO:K02183]
121567694  [KO:K00922] [EC:2.7.1.153]
121567819  [KO:K15909] [EC:3.1.3.86]
121568073  plcd4a; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 [KO:K05857] [EC:3.1.4.11]
121568794  [KO:K21798] [EC:3.1.3.-]
121569171  [KO:K01092] [EC:3.1.3.25]
121569244  [KO:K01106] [EC:3.1.3.56]
121569314  [KO:K00920] [EC:2.7.1.149]
121569328  [KO:K18083] [EC:3.1.3.64 3.1.3.95]
121569347  [KO:K02183]
121569500  plcd3a; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3-A [KO:K05857] [EC:3.1.4.11]
121569624  [KO:K05857] [EC:3.1.4.11]
121569780  [KO:K00999] [EC:2.7.8.11]
121570941  [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
121571070  pip4p1b; type I phosphatidylinositol 4,5-bisphosphate 4-phosphatase-B [KO:K13084] [EC:3.1.3.78]
121571248  [KO:K05858] [EC:3.1.4.11]
121571261  si:dkey-172j4.3; diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
121571279  [KO:K01108] [EC:3.1.3.64 3.1.3.95]
121571280  [KO:K18081] [EC:3.1.3.64 3.1.3.95]
121571796  [KO:K19801] [EC:2.7.1.67]
121572210  pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X1 [KO:K00914] [EC:2.7.1.137]
121572226  [KO:K13084] [EC:3.1.3.78]
121572242  [KO:K21797] [EC:3.1.3.-]
121573452  [KO:K00889] [EC:2.7.1.68]
121573663  [KO:K18081] [EC:3.1.3.64 3.1.3.95]
121573702  [KO:K00911] [EC:2.7.1.127]
121573881  [KO:K00888] [EC:2.7.1.67]
121574185  [KO:K05860] [EC:3.1.4.11]
121574254  [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
121574363  [KO:K18083] [EC:3.1.3.64 3.1.3.95]
121574852  [KO:K13711] [EC:2.7.1.67]
121574978  [KO:K07756] [EC:2.7.4.21]
121575032  [KO:K04958]
121575119  [KO:K01107] [EC:3.1.3.57]
121575124  [KO:K00901] [EC:2.7.1.107]
121575199  [KO:K04958]
121575230  [KO:K07756] [EC:2.7.4.21]
121575399  [KO:K00923] [EC:2.7.1.154]
121575737  [KO:K07756] [EC:2.7.4.21]
121575908  [KO:K00920] [EC:2.7.1.149]
121576695  plcg2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X1 [KO:K05859] [EC:3.1.4.11]
121576787  [KO:K00889] [EC:2.7.1.68]
121576870  [KO:K02649]
121577003  [KO:K04959]
121577563  [KO:K04958]
121577589  [KO:K07756] [EC:2.7.4.21]
121577876  ippk; inositol-pentakisphosphate 2-kinase isoform X1 [KO:K10572] [EC:2.7.1.158]
121577898  [KO:K07756] [EC:2.7.4.21]
121578144  [KO:K00923] [EC:2.7.1.154]
121578220  [KO:K07756] [EC:2.7.4.21]
121578264  itpr1b; inositol 1,4,5-trisphosphate receptor type 1 isoform X1 [KO:K04958]
121578437  [KO:K18086] [EC:3.1.3.64 3.1.3.95]
121578496  [KO:K02183]
121578572  [KO:K01107] [EC:3.1.3.57]
121579135  mtmr4; myotubularin-related protein 4 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
121579478  [KO:K02183]
121579959  [KO:K00911] [EC:2.7.1.127]
121579988  [KO:K18081] [EC:3.1.3.64 3.1.3.95]
121580352  [KO:K18083] [EC:3.1.3.64 3.1.3.95]
121580580  [KO:K01092] [EC:3.1.3.25]
121580697  [KO:K00922] [EC:2.7.1.153]
121580765  [KO:K02649]
121581087  [KO:K02649]
121581162  [KO:K00889] [EC:2.7.1.68]
121581288  [KO:K13084] [EC:3.1.3.78]
121581952  ppip5k2; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X9 [KO:K13024] [EC:2.7.4.24]
121582229  [KO:K00888] [EC:2.7.1.67]
121582535  [KO:K00889] [EC:2.7.1.68]
121582619  [KO:K02649]
121583003  ppip5k1a; LOW QUALITY PROTEIN: inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 [KO:K13024] [EC:2.7.4.24]
121584482  [KO:K00981] [EC:2.7.7.41]
121584610  [KO:K02649]
121584689  [KO:K20278] [EC:3.1.3.36]
121584740  [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
121584844  [KO:K01106] [EC:3.1.3.56]
121584955  [KO:K00889] [EC:2.7.1.68]
121585027  [KO:K00981] [EC:2.7.7.41]
121585832  [KO:K00889] [EC:2.7.1.68]
121586022  [KO:K21797] [EC:3.1.3.-]
121586289  [KO:K00889] [EC:2.7.1.68]
121586718  inpp5b; type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1 [KO:K01099] [EC:3.1.3.36]
121586823  [KO:K21797] [EC:3.1.3.-]
121586848  [KO:K13084] [EC:3.1.3.78]
121586888  [KO:K19801] [EC:2.7.1.67]
121587101  mtmr7a; myotubularin-related protein 7a isoform X1 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
121587263  [KO:K00981] [EC:2.7.7.41]
121587479  [KO:K00888] [EC:2.7.1.67]
123481020  [KO:K19801] [EC:2.7.1.67]
123481271  [KO:K19801] [EC:2.7.1.67]
123483290  [KO:K02677] [EC:2.7.11.13]
123487303  [KO:K00901] [EC:2.7.1.107]
123489630  [KO:K13711] [EC:2.7.1.67]
123491034  [KO:K01099] [EC:3.1.3.36]
Compound
C00076  Calcium cation
C00137  myo-Inositol
C00269  CDP-diacylglycerol
C00416  Phosphatidate
C00641  1,2-Diacyl-sn-glycerol
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11174  1-Diphosinositol pentakisphosphate
C11526  5-PP-InsP5
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C20690  1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
Reference
PMID:19580826
  Authors
Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A
  Title
Mammalian phosphoinositide kinases and phosphatases.
  Journal
Prog Lipid Res 48:307-43 (2009)
DOI:10.1016/j.plipres.2009.06.001
Reference
PMID:19439500
  Authors
Shears SB
  Title
Diphosphoinositol polyphosphates: metabolic messengers?
  Journal
Mol Pharmacol 76:236-52 (2009)
DOI:10.1124/mol.109.055897
Related
pathway
cclu04020  Calcium signaling pathway
cclu04144  Endocytosis
cclu04510  Focal adhesion
KO pathway
ko04070   

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