KEGG   PATHWAY: one00230
Entry
one00230                    Pathway                                
Name
Purine metabolism - Oncorhynchus nerka (sockeye salmon)
Class
Metabolism; Nucleotide metabolism
Pathway map
one00230  Purine metabolism
one00230

Module
one_M00005  PRPP biosynthesis, ribose-5P => PRPP [PATH:one00230]
one_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:one00230]
one_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:one00230]
one_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:one00230]
one_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:one00230]
one_M00546  Purine degradation, xanthine => urea [PATH:one00230]
one_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:one00230]
one_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:one00230]
Other DBs
GO: 0006163 0042278
Organism
Oncorhynchus nerka (sockeye salmon) [GN:one]
Gene
115101146  [KO:K12324] [EC:4.6.1.2]
115101186  [KO:K00939] [EC:2.7.4.3]
115101214  [KO:K01509] [EC:3.6.1.-]
115101248  [KO:K01081] [EC:3.1.3.5]
115101334  [KO:K01939] [EC:6.3.4.4]
115101465  [KO:K12322] [EC:4.6.1.2]
115102182  [KO:K00088] [EC:1.1.1.205]
115102246  [KO:K01490] [EC:3.5.4.6]
115102506  [KO:K01488] [EC:3.5.4.4]
115102673  [KO:K08046] [EC:4.6.1.1]
115102836  [KO:K01510] [EC:3.6.1.5]
115102951  [KO:K00942] [EC:2.7.4.8]
115102992  [KO:K08041] [EC:4.6.1.1]
115103120  [KO:K18436] [EC:3.1.4.53]
115103122  [KO:K12323] [EC:4.6.1.2]
115103243  [KO:K13293] [EC:3.1.4.53]
115103335  [KO:K13293] [EC:3.1.4.53]
115103637  [KO:K13760]
115103880  [KO:K01769] [EC:4.6.1.2]
115104013  [KO:K01756] [EC:4.3.2.2]
115104238  [KO:K13293] [EC:3.1.4.53]
115104560  urad; putative 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K13485] [EC:4.1.1.97]
115104933  [KO:K18436] [EC:3.1.4.53]
115105071  pde1c; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform X1 [KO:K13755] [EC:3.1.4.17]
115105619  [KO:K12321] [EC:4.6.1.2]
115105642  [KO:K10807] [EC:1.17.4.1]
115105646  [KO:K00948] [EC:2.7.6.1]
115105661  [KO:K18283] [EC:3.1.4.17]
115105887  [KO:K13756] [EC:3.1.4.35]
115105889  [KO:K00944] [EC:2.7.4.10]
115105994  [KO:K00944] [EC:2.7.4.10]
115106324  [KO:K00940] [EC:2.7.4.6]
115106354  [KO:K13811] [EC:2.7.7.4 2.7.1.25]
115106380  [KO:K13757] [EC:3.1.4.35]
115106422  nt5m; 5'(3')-deoxyribonucleotidase, mitochondrial [KO:K01081] [EC:3.1.3.5]
115106654  [KO:K08043] [EC:4.6.1.1]
115106739  [KO:K13761] [EC:3.1.4.35]
115106978  [KO:K19021] [EC:3.1.4.17]
115107518  [KO:K00939] [EC:2.7.4.3]
115107589  [KO:K01513] [EC:3.1.4.1 3.6.1.9]
115107615  [KO:K10808] [EC:1.17.4.1]
115107639  [KO:K19970] [EC:3.1.3.5]
115107834  [KO:K01939] [EC:6.3.4.4]
115107914  [KO:K01081] [EC:3.1.3.5]
115107945  allc; probable allantoicase [KO:K01477] [EC:3.5.3.4]
115107985  [KO:K01511] [EC:3.6.1.6]
115108179  [KO:K13293] [EC:3.1.4.53]
115108473  pfas; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
115108542  [KO:K01587] [EC:4.1.1.21 6.3.2.6]
115108543  [KO:K00764] [EC:2.4.2.14]
115108658  ak4; adenylate kinase 4, mitochondrial [KO:K00939] [EC:2.7.4.3]
115108661  [KO:K01835] [EC:5.4.2.2]
115109146  [KO:K13293] [EC:3.1.4.53]
115109372  pde11a; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A [KO:K13298] [EC:3.1.4.17 3.1.4.35]
115109393  [KO:K03783] [EC:2.4.2.1]
115109465  [KO:K00088] [EC:1.1.1.205]
115109491  [KO:K00760] [EC:2.4.2.8]
115109634  [KO:K01490] [EC:3.5.4.6]
115109963  [KO:K00940] [EC:2.7.4.6]
115109965  [KO:K00940] [EC:2.7.4.6]
115110006  nudt9; ADP-ribose pyrophosphatase, mitochondrial isoform X1 [KO:K13988] [EC:3.6.1.13]
115110114  [KO:K01756] [EC:4.3.2.2]
115110214  [KO:K00940] [EC:2.7.4.6]
115110215  [KO:K00940] [EC:2.7.4.6]
115110421  [KO:K12320] [EC:4.6.1.2]
115110464  [KO:K13760]
115110523  [KO:K12320] [EC:4.6.1.2]
115110765  [KO:K08045] [EC:4.6.1.1]
115110884  [KO:K13761] [EC:3.1.4.35]
115111123  [KO:K07127] [EC:3.5.2.17]
115111375  [KO:K01487] [EC:3.5.4.3]
115111384  [KO:K13293] [EC:3.1.4.53]
115111433  [KO:K13755] [EC:3.1.4.17]
115111574  [KO:K12305] [EC:3.6.1.6]
115111982  ak8; adenylate kinase 8 isoform X1 [KO:K00939] [EC:2.7.4.3]
115112207  [KO:K01490] [EC:3.5.4.6]
115112334  [KO:K03783] [EC:2.4.2.1]
115112487  [KO:K08047] [EC:4.6.1.1]
115112916  [KO:K12320] [EC:4.6.1.2]
115112962  [KO:K00856] [EC:2.7.1.20]
115112976  [KO:K13759]
115113296  [KO:K01511] [EC:3.6.1.6]
115113572  [KO:K00759] [EC:2.4.2.7]
115113629  [KO:K01490] [EC:3.5.4.6]
115113630  [KO:K13761] [EC:3.1.4.35]
115113769  [KO:K08047] [EC:4.6.1.1]
115114051  adcy8; adenylate cyclase type 8 isoform X1 [KO:K08048] [EC:4.6.1.1]
115114118  [KO:K13293] [EC:3.1.4.53]
115114225  [KO:K13293] [EC:3.1.4.53]
115114377  pde7a; high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A isoform X1 [KO:K18436] [EC:3.1.4.53]
115114521  [KO:K08041] [EC:4.6.1.1]
115114549  [KO:K03783] [EC:2.4.2.1]
115114567  [KO:K00942] [EC:2.7.4.8]
115114758  [KO:K03783] [EC:2.4.2.1]
115114862  [KO:K01835] [EC:5.4.2.2]
115115788  [KO:K01081] [EC:3.1.3.5]
115115913  [KO:K01939] [EC:6.3.4.4]
115116132  [KO:K01081] [EC:3.1.3.5]
115116666  pde3b; cGMP-inhibited 3',5'-cyclic phosphodiesterase B isoform X1 [KO:K13296] [EC:3.1.4.17]
115116706  [KO:K21138] [EC:3.1.7.2]
115117311  [KO:K18437] [EC:3.1.4.53]
115117685  [KO:K13759]
115117850  [KO:K13762] [EC:3.1.4.35]
115118273  [KO:K01514] [EC:3.6.1.11]
115118671  [KO:K00940] [EC:2.7.4.6]
115118700  [KO:K00106] [EC:1.17.1.4 1.17.3.2]
115119144  lacc1; laccase domain-containing protein 1 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
115119431  [KO:K13987] [EC:3.6.1.13 3.6.1.58 2.7.7.96]
115120219  [KO:K12319] [EC:4.6.1.2]
115120322  [KO:K00948] [EC:2.7.6.1]
115120342  [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
115121028  [KO:K13755] [EC:3.1.4.17]
115121054  [KO:K13758]
115121140  [KO:K13296] [EC:3.1.4.17]
115121694  [KO:K13755] [EC:3.1.4.17]
115121793  [KO:K00088] [EC:1.1.1.205]
115122377  ak6; adenylate kinase isoenzyme 6 isoform X1 [KO:K18532] [EC:2.7.4.3]
115122400  [KO:K12324] [EC:4.6.1.2]
115123085  [KO:K00939] [EC:2.7.4.3]
115123114  [KO:K13759]
115123121  nme6; nucleoside diphosphate kinase 6 isoform X1 [KO:K00940] [EC:2.7.4.6]
115123347  gucy1a2; guanylate cyclase soluble subunit alpha-2 [KO:K12318] [EC:4.6.1.2]
115123399  [KO:K01509] [EC:3.6.1.-]
115123485  [KO:K08048] [EC:4.6.1.1]
115123794  [KO:K01081] [EC:3.1.3.5]
115124120  [KO:K01081] [EC:3.1.3.5]
115124261  [KO:K01081] [EC:3.1.3.5]
115124313  [KO:K01951] [EC:6.3.5.2]
115124348  [KO:K13293] [EC:3.1.4.53]
115125018  [KO:K12318] [EC:4.6.1.2]
115125044  [KO:K01081] [EC:3.1.3.5]
115125509  [KO:K13755] [EC:3.1.4.17]
115125686  [KO:K01490] [EC:3.5.4.6]
115125871  hddc3; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 [KO:K21138] [EC:3.1.7.2]
115125872  [KO:K21138] [EC:3.1.7.2]
115125918  [KO:K13756] [EC:3.1.4.35]
115126107  [KO:K19021] [EC:3.1.4.17]
115126844  [KO:K01466] [EC:3.5.2.5]
115127696  [KO:K01490] [EC:3.5.4.6]
115128175  [KO:K12304] [EC:3.6.1.6]
115128327  [KO:K00939] [EC:2.7.4.3]
115128417  [KO:K01513] [EC:3.1.4.1 3.6.1.9]
115128434  [KO:K01514] [EC:3.6.1.11]
115128449  [KO:K12323] [EC:4.6.1.2]
115128595  [KO:K08042] [EC:4.6.1.1]
115128640  gmpr; GMP reductase 1 [KO:K00364] [EC:1.7.1.7]
115129238  [KO:K00760] [EC:2.4.2.8]
115129314  pde6a; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha [KO:K08718] [EC:3.1.4.35]
115129745  [KO:K00948] [EC:2.7.6.1]
115130118  adcy5; adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
115130135  [KO:K18436] [EC:3.1.4.53]
115130849  [KO:K16855] [EC:3.6.1.62 3.6.1.64]
115131142  [KO:K01769] [EC:4.6.1.2]
115131254  [KO:K10808] [EC:1.17.4.1]
115131549  [KO:K12323] [EC:4.6.1.2]
115131566  prune1; exopolyphosphatase PRUNE1 isoform X1 [KO:K01514] [EC:3.6.1.11]
115131669  [KO:K00939] [EC:2.7.4.3]
115131798  [KO:K08044] [EC:4.6.1.1]
115131919  [KO:K08046] [EC:4.6.1.1]
115131974  [KO:K00088] [EC:1.1.1.205]
115132037  atic; bifunctional purine biosynthesis protein PURH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
115132227  [KO:K01490] [EC:3.5.4.6]
115132460  [KO:K01488] [EC:3.5.4.4]
115132942  adcy10; adenylate cyclase type 10 [KO:K11265] [EC:4.6.1.1]
115132995  [KO:K00948] [EC:2.7.6.1]
115133048  [KO:K19572] [EC:3.5.4.4]
115133094  [KO:K13987] [EC:3.6.1.13 3.6.1.58 2.7.7.96]
115133390  [KO:K03783] [EC:2.4.2.1]
115133758  [KO:K00364] [EC:1.7.1.7]
115133824  [KO:K19021] [EC:3.1.4.17]
115134007  [KO:K01490] [EC:3.5.4.6]
115134053  [KO:K19572] [EC:3.5.4.4]
115134205  [KO:K00088] [EC:1.1.1.205]
115134535  gart; trifunctional purine biosynthetic protein adenosine-3 isoform X1 [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
115134736  [KO:K00760] [EC:2.4.2.8]
115134759  [KO:K03783] [EC:2.4.2.1]
115134790  [KO:K01081] [EC:3.1.3.5]
115135100  [KO:K13811] [EC:2.7.7.4 2.7.1.25]
115135182  [KO:K01081] [EC:3.1.3.5]
115135362  [KO:K00856] [EC:2.7.1.20]
115135620  [KO:K01939] [EC:6.3.4.4]
115135797  [KO:K18283] [EC:3.1.4.17]
115135815  [KO:K00948] [EC:2.7.6.1]
115135824  [KO:K10807] [EC:1.17.4.1]
115135839  [KO:K12321] [EC:4.6.1.2]
115136093  [KO:K13761] [EC:3.1.4.35]
115136165  [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
115136573  [KO:K01951] [EC:6.3.5.2]
115136628  [KO:K12322] [EC:4.6.1.2]
115137125  [KO:K13761] [EC:3.1.4.35]
115137233  gucy1a1; guanylate cyclase soluble subunit alpha-1 [KO:K12318] [EC:4.6.1.2]
115137234  gucy1b1; guanylate cyclase soluble subunit beta-1 isoform X1 [KO:K12319] [EC:4.6.1.2]
115137942  [KO:K03783] [EC:2.4.2.1]
115137966  [KO:K00364] [EC:1.7.1.7]
115138198  [KO:K13762] [EC:3.1.4.35]
115138430  [KO:K01081] [EC:3.1.3.5]
115138458  [KO:K01939] [EC:6.3.4.4]
115138523  [KO:K01511] [EC:3.6.1.6]
115139165  [KO:K01081] [EC:3.1.3.5]
115139205  [KO:K01511] [EC:3.6.1.6]
115139286  ak9; adenylate kinase 9 isoform X1 [KO:K18533] [EC:2.7.4.3 2.7.4.6]
115139332  [KO:K08043] [EC:4.6.1.1]
115139343  [KO:K01939] [EC:6.3.4.4]
115139545  [KO:K00365] [EC:1.7.3.3]
115139608  [KO:K19970] [EC:3.1.3.5]
115139620  [KO:K01490] [EC:3.5.4.6]
115139636  rrm2; ribonucleoside-diphosphate reductase subunit M2 [KO:K10808] [EC:1.17.4.1]
115139663  [KO:K01513] [EC:3.1.4.1 3.6.1.9]
115139814  [KO:K01487] [EC:3.5.4.3]
115139824  [KO:K13293] [EC:3.1.4.53]
115139865  [KO:K01509] [EC:3.6.1.-]
115140099  [KO:K00904] [EC:2.7.1.113]
115140427  [KO:K12324] [EC:4.6.1.2]
115140444  [KO:K01081] [EC:3.1.3.5]
115140497  hddc2; HD domain-containing protein 2 [KO:K07023] [EC:3.1.3.89]
115140957  [KO:K01510] [EC:3.6.1.5]
115140990  [KO:K12323] [EC:4.6.1.2]
115141002  [KO:K03783] [EC:2.4.2.1]
115141050  [KO:K01769] [EC:4.6.1.2]
115141418  [KO:K08043] [EC:4.6.1.1]
115141487  [KO:K13761] [EC:3.1.4.35]
115141944  [KO:K12322] [EC:4.6.1.2]
115142115  [KO:K01510] [EC:3.6.1.5]
115142270  [KO:K12319] [EC:4.6.1.2]
115142972  [KO:K01510] [EC:3.6.1.5]
115143021  [KO:K03783] [EC:2.4.2.1]
115143188  [KO:K01490] [EC:3.5.4.6]
115143264  nudt2; bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] isoform X1 [KO:K01518] [EC:3.6.1.17]
115143307  fhit; bis(5'-adenosyl)-triphosphatase [KO:K01522] [EC:3.6.1.29]
115144029  [KO:K13757] [EC:3.1.4.35]
115144179  [KO:K12320] [EC:4.6.1.2]
115144341  [KO:K01939] [EC:6.3.4.4]
115144570  [KO:K00940] [EC:2.7.4.6]
115144576  adprm; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
115144815  [KO:K07127] [EC:3.5.2.17]
115145144  [KO:K01587] [EC:4.1.1.21 6.3.2.6]
115145145  ppat; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
115145291  [KO:K13758]
115145335  [KO:K01835] [EC:5.4.2.2]
115145342  [KO:K00939] [EC:2.7.4.3]
115145483  itpa; inosine triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
115145808  [KO:K12319] [EC:4.6.1.2]
115145970  [KO:K00939] [EC:2.7.4.3]
115146127  enpp4; bis(5'-adenosyl)-triphosphatase ENPP4 isoform X1 [KO:K18424] [EC:3.6.1.29]
115146211  [KO:K01511] [EC:3.6.1.6]
115146260  [KO:K01939] [EC:6.3.4.4]
115146402  [KO:K19970] [EC:3.1.3.5]
115146500  [KO:K01081] [EC:3.1.3.5]
115146565  [KO:K12318] [EC:4.6.1.2]
115147172  pde8b; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1 [KO:K18437] [EC:3.1.4.53]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
one00030  Pentose phosphate pathway
one00220  Arginine biosynthesis
one00250  Alanine, aspartate and glutamate metabolism
one00260  Glycine, serine and threonine metabolism
one00340  Histidine metabolism
one00630  Glyoxylate and dicarboxylate metabolism
one00730  Thiamine metabolism
one00740  Riboflavin metabolism
one00790  Folate biosynthesis
KO pathway
ko00230   

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