KEGG   PATHWAY: pmoa04820
Entry
pmoa04820                   Pathway                                
Name
Cytoskeleton in muscle cells - Passer montanus (Eurasian tree sparrow)
Class
Cellular Processes; Cell motility
Pathway map
pmoa04820  Cytoskeleton in muscle cells
pmoa04820

Organism
Passer montanus (Eurasian tree sparrow) [GN:pmoa]
Gene
120498153  ADAT3; probable inactive tRNA-specific adenosine deaminase-like protein 3 [KO:K06236]
120498206  COL1A1; collagen alpha-1(I) chain [KO:K06236]
120501932  COL1A2; collagen alpha-2(I) chain [KO:K06236]
120509489  LBX2; transcription factor LBX2 [KO:K19720]
120511514  COL3A1; collagen alpha-1(III) chain [KO:K19720]
120510879  COL24A1; collagen alpha-1(XXIV) chain isoform X1 [KO:K19721]
120511533  COL5A2; collagen alpha-2(V) chain isoform X1 [KO:K19721]
120506530  COL11A1; collagen alpha-1(XI) chain isoform X1 [KO:K19721]
120512424  COL5A1; collagen alpha-1(V) chain isoform X1 [KO:K19721]
120507465  collagen alpha-1(XXVII) chain-like [KO:K19721]
120507526  collagen alpha-1(I) chain-like isoform X1 [KO:K19721]
120511395  COL9A1; collagen alpha-1(IX) chain [KO:K08131]
120507040  COL9A3; LOW QUALITY PROTEIN: collagen alpha-3(IX) chain [KO:K08131]
120513918  COL9A2; collagen alpha-2(IX) chain [KO:K08131]
120499853  DCN; decorin [KO:K04660]
120496177  VCAN; versican core protein isoform X1 [KO:K06793]
120513474  ELN; elastin isoform X1 [KO:K14211]
120498362  COL6A1; collagen alpha-1(VI) chain [KO:K06238]
120498369  COL6A2; collagen alpha-2(VI) chain isoform X1 [KO:K06238]
120504130  COL6A6; LOW QUALITY PROTEIN: collagen alpha-6(VI) chain [KO:K06238]
120511532  COL6A3; collagen alpha-3(VI) chain isoform X1 [KO:K06238]
120500320  THBS1; thrombospondin-1 [KO:K16857]
120498934  THBS3; thrombospondin-3 [KO:K04659]
120499021  cartilage oligomeric matrix protein isoform X1 [KO:K04659]
120501393  THBS2; thrombospondin-2 isoform X1 [KO:K04659]
120502375  THBS4; thrombospondin-4 [KO:K04659]
120509060  FBN1; fibrillin-1 isoform X1 [KO:K06825]
120501793  fibrillin-2-like [KO:K23342]
120513715  FBN3; fibrillin-3 [KO:K23342]
120504586  COL4A2; collagen alpha-2(IV) chain [KO:K06237]
120504588  COL4A1; collagen alpha-1(IV) chain [KO:K06237]
120506229  COL4A6; collagen alpha-6(IV) chain isoform X1 [KO:K06237]
120506230  COL4A5; collagen alpha-5(IV) chain isoform X1 [KO:K06237]
120508627  COL4A4; collagen alpha-4(IV) chain isoform X1 [KO:K06237]
120508629  COL4A3; collagen alpha-3(IV) chain isoform X1 [KO:K06237]
120501591  FBLN1; fibulin-1 isoform X1 [KO:K17307]
120495973  latent-transforming growth factor beta-binding protein 4-like [KO:K17307]
120502656  FBLN2; fibulin-2 isoform X1 [KO:K17307]
120496722  HSPG2; basement membrane-specific heparan sulfate proteoglycan core protein [KO:K06255]
120500707  NID2; nidogen-2 [KO:K06826]
120501111  NID1; nidogen-1 [KO:K06826]
120511486  FN1; fibronectin isoform X1 [KO:K05717]
120508249  SDC1; syndecan-1 [KO:K06257]
120500752  SDC2; syndecan-2 [KO:K16336]
120511654  SDC3; syndecan-3 [KO:K16337]
120511292  SDC4; syndecan-4 [KO:K16338]
120511020  AGRN; LOW QUALITY PROTEIN: agrin [KO:K06254]
120512151  DSG2; desmoglein-2 [KO:K07597]
120501701  PKP2; plakophilin-2 isoform X1 [KO:K12642]
120496670  junction plakoglobin [KO:K10056]
120503555  desmoplakin isoform X1 [KO:K10381]
120501144  VIM; vimentin [KO:K07606]
120496829  DES; desmin [KO:K07610]
120500830  LAMA1; laminin subunit alpha-1 [KO:K05637]
120501091  LAMA2; laminin subunit alpha-2 isoform X1 [KO:K05637]
120502497  ITGA1; integrin alpha-1 [KO:K06480]
120502329  ITGA2; integrin alpha-2 isoform X1 [KO:K06481]
120498295  ITGA2B; integrin alpha-IIb isoform X1 [KO:K06476]
120498172  ITGA3; integrin alpha-3 isoform X1 [KO:K06482]
120497715  ITGA4; integrin alpha-4 [KO:K06483]
120504832  LOW QUALITY PROTEIN: integrin alpha-5-like [KO:K06484]
120513377  ITGA6; integrin alpha-6 isoform X1 [KO:K06485]
120503925  ITGA7; integrin alpha-7 [KO:K06583]
120503769  ITGA8; integrin alpha-8 [KO:K06584]
120505023  ITGA9; integrin alpha-9 isoform X1 [KO:K06585]
120506967  ITGA10; integrin alpha-10 [KO:K06586]
120509192  ITGA11; integrin alpha-11 [KO:K06587]
120511498  ITGAV; integrin alpha-V [KO:K06487]
120502076  ITGB1; integrin beta-1 isoform X1 [KO:K05719]
120498400  ITGB3; integrin beta-3 isoform X1 [KO:K06493]
120505405  ITGB4; integrin beta-4 [KO:K06525]
120498892  ITGB5; integrin beta-5 [KO:K06588]
120498509  ITGB6; integrin beta-6 [KO:K06589]
120502817  ITGB8; integrin beta-8 isoform X1 [KO:K06591]
120508861  TLN2; talin-2 isoform X1 [KO:K06271]
120502534  TLN1; talin-1 isoform X1 [KO:K06271]
120510924  VCL; vinculin isoform X1 [KO:K05700]
120501307  ACTN2; alpha-actinin-2 [KO:K21073]
120504844  actin [KO:K05692]
120505418  ACTG1; actin, cytoplasmic 2 [KO:K05692]
120513236  ACTB; actin, cytoplasmic 1 isoform X1 [KO:K05692]
120499148  ACTG2; actin, gamma-enteric smooth muscle [KO:K12315]
120495690  DAG1; dystroglycan [KO:K06265]
120498186  SGCA; alpha-sarcoglycan [KO:K12565]
120502159  SGCE; epsilon-sarcoglycan isoform X1 [KO:K27061]
120497420  SGCB; beta-sarcoglycan [KO:K12566]
120498447  SGCD; delta-sarcoglycan isoform X1 [KO:K12563]
120506780  SGCG; gamma-sarcoglycan isoform X1 [KO:K12564]
120497428  SGCZ; zeta-sarcoglycan [KO:K27062]
120501594  SSPN; LOW QUALITY PROTEIN: sarcospan [KO:K22194]
120504570  DMD; dystrophin isoform X1 [KO:K10366]
120511309  SNTA1; alpha-1-syntrophin [KO:K24063]
120505161  SNTB1; beta-1-syntrophin [KO:K24064]
120496277  SNTB2; beta-2-syntrophin [KO:K24064]
120499329  DTNA; dystrobrevin alpha isoform X1 [KO:K26998]
120500092  FLNC; filamin-C isoform X1 [KO:K27393]
120504822  LOW QUALITY PROTEIN: sodium/potassium-transporting ATPase subunit alpha-2-like [KO:K01539] [EC:7.2.2.13]
120506317  ATP1A1; sodium/potassium-transporting ATPase subunit alpha-1 [KO:K01539] [EC:7.2.2.13]
120506106  ATP1B4; protein ATP1B4 [KO:K01540]
120506399  ATP1B1; sodium/potassium-transporting ATPase subunit beta-1 [KO:K01540]
120495820  sodium/potassium-transporting ATPase subunit beta-2-like [KO:K01540]
120508558  ATP1B3; sodium/potassium-transporting ATPase subunit beta-3 [KO:K01540]
120507286  ANK3; ankyrin-3 isoform X1 [KO:K09259]
120507469  SPTAN1; spectrin alpha chain, non-erythrocytic 1 isoform X1 [KO:K06114]
120506026  SPTBN1; spectrin beta chain, non-erythrocytic 1 isoform X1 [KO:K06115]
120500286  SPTBN5; spectrin beta chain, non-erythrocytic 5 [KO:K06115]
120508284  SPTBN4; spectrin beta chain, non-erythrocytic 4 [KO:K06115]
120504956  LOW QUALITY PROTEIN: spectrin beta chain, non-erythrocytic 2-like [KO:K23932]
120497301  CSRP1; cysteine and glycine-rich protein 1 [KO:K09377]
120509891  CSRP3; cysteine and glycine-rich protein 3 [KO:K09377]
120499903  CSRP2; cysteine and glycine-rich protein 2 [KO:K09377]
120498271  myosin heavy chain, skeletal muscle, adult-like [KO:K24220]
120498275  myosin-3-like [KO:K24220]
120504455  LOW QUALITY PROTEIN: myosin heavy chain, skeletal muscle, adult-like [KO:K24220]
120504458  myosin heavy chain, skeletal muscle, adult [KO:K24220]
120505413  myosin-1B-like [KO:K24220]
120505665  myosin-13 [KO:K24220]
120511350  MYH7B; myosin-7B isoform X1 [KO:K24220]
120513394  MYH15; myosin-15 isoform X1 [KO:K24220]
120504156  myosin-6 isoform X1 [KO:K17751]
120504905  LOW QUALITY PROTEIN: myosin-7-like [KO:K17751]
120497144  myosin-6-like [KO:K10352]
120498254  MYH10; myosin-10 [KO:K10352]
120510010  MYH9; myosin-9 [KO:K10352]
120505666  myosin-1B-like [KO:K10352]
120512884  MYH11; myosin-11 isoform X1 [KO:K10352]
120511560  MYL1; myosin light chain 1/3, skeletal muscle isoform isoform X1 [KO:K05738]
120510605  MYL3; myosin light chain 3 [KO:K12749]
120498210  myosin light chain, embryonic [KO:K12750]
120509775  MYL2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351]
120497731  MYL9; myosin regulatory light polypeptide 9 [KO:K12755]
120501547  MYBPC1; myosin-binding protein C, slow-type isoform X1 [KO:K12557]
120500413  MYBPC3; myosin-binding protein C, cardiac-type isoform X1 [KO:K12568]
120497298  MYBPH; myosin-binding protein H [KO:K24494]
120501198  ACTA1; actin, alpha skeletal muscle [KO:K10354]
120500352  ACTC1; actin, alpha cardiac muscle 1 [KO:K12314]
120514170  TNNC1; troponin C, slow skeletal and cardiac muscles [KO:K05865]
120497282  TNNI1; troponin I, slow skeletal muscle [KO:K10371]
120497817  TNNC2; troponin C, skeletal muscle [KO:K12042]
120511443  TNNI2; troponin I, fast skeletal muscle [KO:K12043]
120511438  TNNT3; troponin T, fast skeletal muscle isoform X1 [KO:K12046]
120507895  troponin I, cardiac muscle-like [KO:K12044]
120497295  TNNT2; troponin T, cardiac muscle isoform X1 [KO:K12045]
120508951  TPM1; tropomyosin alpha-1 chain isoform X1 [KO:K10373]
120502371  TPM2; tropomyosin beta chain isoform X1 [KO:K10374]
120498880  TPM3; tropomyosin alpha-3 chain isoform X1 [KO:K09290]
120514179  TPM4; tropomyosin alpha-4 chain isoform X1 [KO:K10375]
120499312  TTN; titin [KO:K12567] [EC:2.7.11.1]
120498434  MYOT; myotilin isoform X1 [KO:K19875]
120496569  telethonin [KO:K19879]
120508725  SYNPO2; synaptopodin-2 isoform X1 [KO:K24066]
120497330  nebulin-like [KO:K18267]
120502952  NEB; nebulin [KO:K18267]
120500228  NEBL; nebulette isoform X1 [KO:K25865]
120510935  MYOZ1; myozenin-1 isoform X1 [KO:K26050]
120508952  MYOZ2; myozenin-2 [KO:K26050]
120498580  MYOZ3; myozenin-3 isoform X1 [KO:K26050]
120497149  PDLIM2; PDZ and LIM domain protein 2 isoform X1 [KO:K23353]
120498025  PDLIM3; PDZ and LIM domain protein 3 isoform X1 [KO:K23353]
120498708  PDLIM4; PDZ and LIM domain protein 4 isoform X1 [KO:K23353]
120510939  PDLIM1; PDZ and LIM domain protein 1 isoform X1 [KO:K23353]
120510690  CAPZA2; F-actin-capping protein subunit alpha-2 [KO:K10364]
120495902  CAPZA1; F-actin-capping protein subunit alpha-1 [KO:K10364]
120501681  CAPZA3; LOW QUALITY PROTEIN: F-actin-capping protein subunit alpha-3 [KO:K10364]
120499402  CAPZB; F-actin-capping protein subunit beta isoform X1 [KO:K10365]
120501612  XIRP1; xin actin-binding repeat-containing protein 1 [KO:K27381]
120501922  nebulin-related-anchoring protein isoform X1 [KO:K24421]
120496110  MYPN; myopalladin isoform X1 [KO:K22028]
120502787  PDLIM5; PDZ and LIM domain protein 5 isoform X1 [KO:K19867]
120498490  PDLIM7; PDZ and LIM domain protein 7 isoform X1 [KO:K19867]
120507306  LDB3; LIM domain-binding protein 3 isoform X1 [KO:K19867]
120508992  tropomodulin-2 [KO:K10370]
120509043  tropomodulin-3-like [KO:K10370]
120503946  TMOD4; tropomodulin-4 isoform X1 [KO:K10370]
120513607  TMOD1; tropomodulin-1 [KO:K10370]
120506324  ZYX; zyxin isoform X1 [KO:K06273]
120508682  FHL1; four and a half LIM domains protein 1 isoform X1 [KO:K14365]
120504732  FHL2; four and a half LIM domains protein 2 [KO:K14380]
120511698  FHL3; four and a half LIM domains protein 3 isoform X1 [KO:K24414]
120502905  LMOD1; leiomodin-1 [KO:K22030]
120510766  LMOD2; leiomodin-2 [KO:K22030]
120495705  LMOD3; leiomodin-3 [KO:K22030]
120501925  ANKRD1; ankyrin repeat domain-containing protein 1 [KO:K21433]
120502205  ANKRD2; ankyrin repeat domain-containing protein 2 [KO:K21434]
120497325  FMNL2; formin-like protein 2 isoform X1 [KO:K23957]
120498321  FMNL1; formin-like protein 1 isoform X1 [KO:K23957]
120499464  FMNL3; formin-like protein 3 [KO:K23957]
120503797  INF2; inverted formin-2 isoform X1 [KO:K23958]
120503872  inverted formin-2-like [KO:K23958]
120513522  DAAM1; disheveled-associated activator of morphogenesis 1 isoform X1 [KO:K04512]
120496989  DAAM2; disheveled-associated activator of morphogenesis 2 isoform X1 [KO:K04512]
120508687  DIAPH2; protein diaphanous homolog 2 isoform X1 [KO:K05741]
120505795  DIAPH3; protein diaphanous homolog 3 [KO:K05745]
120501320  FMN2; formin-2 isoform X1 [KO:K02184]
120505323  MYOM2; myomesin-2 isoform X1 [KO:K24495]
120500732  MYOM1; myomesin-1 isoform X1 [KO:K24495]
120513882  MYOM3; myomesin-3 [KO:K24495]
120511010  ENO1; alpha-enolase isoform X1 [KO:K01689] [EC:4.2.1.11]
120506505  ENO2; gamma-enolase [KO:K01689] [EC:4.2.1.11]
120502781  ANK2; ankyrin-2 isoform X1 [KO:K09255]
120496152  creatine kinase M-type-like [KO:K27382] [EC:2.7.3.2]
120503060  creatine kinase M-type-like [KO:K27382] [EC:2.7.3.2]
120502875  TRIM54; tripartite motif-containing protein 54 [KO:K10653]
120499370  TRIM55; tripartite motif-containing protein 55 isoform X1 [KO:K10654]
120513891  TRIM63; E3 ubiquitin-protein ligase TRIM63 isoform X1 [KO:K10655] [EC:2.3.2.27]
120497644  AMPD1; AMP deaminase 1 isoform X1 [KO:K01490] [EC:3.5.4.6]
120503426  AMPD2; AMP deaminase 2 [KO:K01490] [EC:3.5.4.6]
120501079  AMPD3; AMP deaminase 3 isoform X1 [KO:K01490] [EC:3.5.4.6]
120510525  OBSCN; obscurin [KO:K17531] [EC:2.7.11.1]
120500534  CAPN3; calpain-3 isoform X1 [KO:K08573] [EC:3.4.22.54]
120502894  PLEC; plectin [KO:K10388]
120503752  SYNE3; nesprin-3 isoform X1 [KO:K21761]
120501289  SYNE1; nesprin-1 isoform X1 [KO:K19326]
120513544  SYNE2; nesprin-2 [KO:K19346]
120510031  SUN2; SUN domain-containing protein 2 [KO:K19347]
120513004  SUN1; SUN domain-containing protein 1 isoform X1 [KO:K19347]
120495751  TMEM43; transmembrane protein 43 isoform X1 [KO:K27488]
120505974  LBR; delta(14)-sterol reductase LBR [KO:K19532] [EC:1.3.1.70]
120498877  LMNA; lamin [KO:K12641]
120508879  lamin-L(III)-like isoform X1 [KO:K07611]
120496352  LMNB2; lamin-B2 [KO:K07611]
120502666  LMNB1; lamin-B1 [KO:K07611]
Reference
PMID:12142273
  Authors
Clark KA, McElhinny AS, Beckerle MC, Gregorio CC
  Title
Striated muscle cytoarchitecture: an intricate web of form and function.
  Journal
Annu Rev Cell Dev Biol 18:637-706 (2002)
DOI:10.1146/annurev.cellbio.18.012502.105840
Reference
PMID:31407867
  Authors
Mukund K, Subramaniam S
  Title
Skeletal muscle: A review of molecular structure and function, in health and disease.
  Journal
Wiley Interdiscip Rev Syst Biol Med 12:e1462 (2020)
DOI:10.1002/wsbm.1462
Reference
PMID:24481844
  Authors
Stroud MJ, Banerjee I, Veevers J, Chen J
  Title
Linker of nucleoskeleton and cytoskeleton complex proteins in cardiac structure, function, and disease.
  Journal
Circ Res 114:538-48 (2014)
DOI:10.1161/CIRCRESAHA.114.301236
Reference
PMID:28640448
  Authors
Henderson CA, Gomez CG, Novak SM, Mi-Mi L, Gregorio CC
  Title
Overview of the Muscle Cytoskeleton.
  Journal
Compr Physiol 7:891-944 (2017)
DOI:10.1002/cphy.c160033
Reference
PMID:32265741
  Authors
Csapo R, Gumpenberger M, Wessner B
  Title
Skeletal Muscle Extracellular Matrix - What Do We Know About Its Composition, Regulation, and Physiological Roles? A Narrative Review.
  Journal
Front Physiol 11:253 (2020)
DOI:10.3389/fphys.2020.00253
Reference
PMID:27114860
  Authors
Pinch M, Guth R, Samanta MP, Chaidez A, Unguez GA
  Title
The myogenic electric organ of Sternopygus macrurus: a non-contractile tissue with a skeletal muscle transcriptome.
  Journal
PeerJ 4:e1828 (2016)
DOI:10.7717/peerj.1828
Reference
PMID:23860255
  Authors
Sequeira V, Nijenkamp LL, Regan JA, van der Velden J
  Title
The physiological role of cardiac cytoskeleton and its alterations in heart failure.
  Journal
Biochim Biophys Acta 1838:700-22 (2014)
DOI:10.1016/j.bbamem.2013.07.011
Reference
PMID:36960155
  Authors
Zhang B, Powers JD, McCulloch AD, Chi NC
  Title
Nuclear mechanosignaling in striated muscle diseases.
  Journal
Front Physiol 14:1126111 (2023)
DOI:10.3389/fphys.2023.1126111
Reference
PMID:21464301
  Authors
Al-Amoudi A, Castano-Diez D, Devos DP, Russell RB, Johnson GT, Frangakis AS
  Title
The three-dimensional molecular structure of the desmosomal plaque.
  Journal
Proc Natl Acad Sci U S A 108:6480-5 (2011)
DOI:10.1073/pnas.1019469108
Reference
PMID:33067392
  Authors
Sikora M, Ermel UH, Seybold A, Kunz M, Calloni G, Reitz J, Vabulas RM, Hummer G, Frangakis AS
  Title
Desmosome architecture derived from molecular dynamics simulations and cryo-electron tomography.
  Journal
Proc Natl Acad Sci U S A 117:27132-27140 (2020)
DOI:10.1073/pnas.2004563117
Reference
PMID:26910421
  Authors
Xu XP, Kim E, Swift M, Smith JW, Volkmann N, Hanein D
  Title
Three-Dimensional Structures of Full-Length, Membrane-Embedded Human alpha(IIb)beta(3) Integrin Complexes.
  Journal
Biophys J 110:798-809 (2016)
DOI:10.1016/j.bpj.2016.01.016
Reference
PMID:22945352
  Authors
Wang W, Shi Z, Jiao S, Chen C, Wang H, Liu G, Wang Q, Zhao Y, Greene MI, Zhou Z
  Title
Structural insights into SUN-KASH complexes across the nuclear envelope.
  Journal
Cell Res 22:1440-52 (2012)
DOI:10.1038/cr.2012.126
Reference
PMID:23597672
  Authors
Sosa BA, Kutay U, Schwartz TU
  Title
Structural insights into LINC complexes.
  Journal
Curr Opin Struct Biol 23:285-91 (2013)
DOI:10.1016/j.sbi.2013.03.005
Reference
PMID:33058875
  Authors
Cruz VE, Esra Demircioglu F, Schwartz TU
  Title
Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes.
  Journal
J Mol Biol 432:6028-6041 (2020)
DOI:10.1016/j.jmb.2020.09.019
Reference
PMID:36523505
  Authors
Schuler SC, Liu Y, Dumontier S, Grandbois M, Le Moal E, Cornelison D, Bentzinger CF
  Title
Extracellular matrix: Brick and mortar in the skeletal muscle stem cell niche.
  Journal
Front Cell Dev Biol 10:1056523 (2022)
DOI:10.3389/fcell.2022.1056523
Reference
PMID:30425656
  Authors
Brull A, Morales Rodriguez B, Bonne G, Muchir A, Bertrand AT
  Title
The Pathogenesis and Therapies of Striated Muscle Laminopathies.
  Journal
Front Physiol 9:1533 (2018)
DOI:10.3389/fphys.2018.01533
Reference
PMID:36552829
  Authors
Storey EC, Fuller HR
  Title
Genotype-Phenotype Correlations in Human Diseases Caused by Mutations of LINC Complex-Associated Genes: A Systematic Review and Meta-Summary.
  Journal
Cells 11:cells11244065 (2022)
DOI:10.3390/cells11244065
Related
pathway
pmoa04512  ECM-receptor interaction
pmoa04814  Motor proteins
KO pathway
ko04820   
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