KEGG   PATHWAY: pspa00230
Entry
pspa00230                   Pathway                                
Name
Purine metabolism - Polyodon spathula (Mississippi paddlefish)
Class
Metabolism; Nucleotide metabolism
Pathway map
pspa00230  Purine metabolism
pspa00230

Module
pspa_M00005  PRPP biosynthesis, ribose-5P => PRPP [PATH:pspa00230]
pspa_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:pspa00230]
pspa_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:pspa00230]
pspa_M00546  Purine degradation, xanthine => urea [PATH:pspa00230]
pspa_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:pspa00230]
pspa_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:pspa00230]
Other DBs
GO: 0006163 0042278
Organism
Polyodon spathula (Mississippi paddlefish) [GN:pspa]
Gene
121294111  [KO:K13759]
121294570  hddc3; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 [KO:K21138] [EC:3.1.7.2]
121294654  [KO:K13296] [EC:3.1.4.17]
121294757  [KO:K18437] [EC:3.1.4.53]
121294788  ampd3b; AMP deaminase 3b [KO:K01490] [EC:3.5.4.6]
121295113  [KO:K01081] [EC:3.1.3.5]
121295205  gucy1b1; guanylate cyclase soluble subunit beta-1 [KO:K12319] [EC:4.6.1.2]
121295308  [KO:K13759]
121295425  [KO:K01081] [EC:3.1.3.5]
121295487  [KO:K13762] [EC:3.1.4.35]
121295496  [KO:K01120] [EC:3.1.4.17]
121295615  [KO:K00948] [EC:2.7.6.1]
121295623  [KO:K00940] [EC:2.7.4.6]
121295624  [KO:K00940] [EC:2.7.4.6]
121295646  cant1b; soluble calcium-activated nucleotidase 1b [KO:K12304] [EC:3.6.1.6]
121295670  [KO:K00760] [EC:2.4.2.8]
121295713  pde6b; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta isoform X1 [KO:K13756] [EC:3.1.4.35]
121295923  [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
121296075  [KO:K00940] [EC:2.7.4.6]
121296076  [KO:K00940] [EC:2.7.4.6]
121296143  [KO:K07127] [EC:3.5.2.17]
121296167  [KO:K08047] [EC:4.6.1.1]
121296255  [KO:K12304] [EC:3.6.1.6]
121296329  [KO:K07127] [EC:3.5.2.17]
121296422  [KO:K13811] [EC:2.7.7.4 2.7.1.25]
121296479  [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
121296584  [KO:K13759]
121296607  [KO:K00760] [EC:2.4.2.8]
121296674  [KO:K03783] [EC:2.4.2.1]
121297460  [KO:K08718] [EC:3.1.4.35]
121297499  [KO:K01769] [EC:4.6.1.2]
121297937  [KO:K00944] [EC:2.7.4.10]
121297969  ada; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
121298345  impdh2; inosine-5'-monophosphate dehydrogenase 2 [KO:K00088] [EC:1.1.1.205]
121298480  [KO:K01522] [EC:3.6.1.29]
121298526  [KO:K21138] [EC:3.1.7.2]
121298907  [KO:K18437] [EC:3.1.4.53]
121299124  [KO:K01487] [EC:3.5.4.3]
121299675  [KO:K01490] [EC:3.5.4.6]
121299809  ampd1; AMP deaminase 1 [KO:K01490] [EC:3.5.4.6]
121299812  [KO:K01490] [EC:3.5.4.6]
121300169  [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
121300452  [KO:K08049] [EC:4.6.1.1]
121300555  [KO:K13293] [EC:3.1.4.53]
121300832  [KO:K13293] [EC:3.1.4.53]
121300880  nme3; nucleoside diphosphate kinase 3 [KO:K00940] [EC:2.7.4.6]
121300985  [KO:K13759]
121301411  [KO:K13293] [EC:3.1.4.53]
121301817  [KO:K12324] [EC:4.6.1.2]
121302384  [KO:K00904] [EC:2.7.1.113]
121302434  [KO:K12305] [EC:3.6.1.6]
121302699  urad; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K13485] [EC:4.1.1.97]
121302884  rrm1; ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
121303196  [KO:K01081] [EC:3.1.3.5]
121303352  ak2; adenylate kinase 2, mitochondrial isoform X1 [KO:K00939] [EC:2.7.4.3]
121303531  [KO:K00939] [EC:2.7.4.3]
121303621  [KO:K00939] [EC:2.7.4.3]
121304784  [KO:K01518] [EC:3.6.1.17]
121305242  [KO:K18437] [EC:3.1.4.53]
121305249  [KO:K08044] [EC:4.6.1.1]
121305304  [KO:K03783] [EC:2.4.2.1]
121305328  [KO:K00364] [EC:1.7.1.7]
121305656  [KO:K12321] [EC:4.6.1.2]
121306199  [KO:K12320] [EC:4.6.1.2]
121306511  [KO:K18532] [EC:2.7.4.3]
121306722  entpd8; ectonucleoside triphosphate diphosphohydrolase 8 [KO:K01510] [EC:3.6.1.5]
121306793  nudt9; ADP-ribose pyrophosphatase, mitochondrial [KO:K13988] [EC:3.6.1.13]
121306985  [KO:K12323] [EC:4.6.1.2]
121307145  nudt2; bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] isoform X1 [KO:K01518] [EC:3.6.1.17]
121307360  [KO:K08044] [EC:4.6.1.1]
121307396  [KO:K03783] [EC:2.4.2.1]
121307574  [KO:K12304] [EC:3.6.1.6]
121307599  aprt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
121308376  [KO:K10808] [EC:1.17.4.1]
121308378  [KO:K01081] [EC:3.1.3.5]
121308576  [KO:K01510] [EC:3.6.1.5]
121308907  [KO:K13755] [EC:3.1.4.17]
121309011  adcy6a; adenylate cyclase type 6 isoform X1 [KO:K08046] [EC:4.6.1.1]
121309014  adcy8; adenylate cyclase type 8 [KO:K08048] [EC:4.6.1.1]
121309143  [KO:K13293] [EC:3.1.4.53]
121309281  [KO:K00088] [EC:1.1.1.205]
121309305  [KO:K08042] [EC:4.6.1.1]
121309463  [KO:K13761] [EC:3.1.4.35]
121309704  ak8; adenylate kinase 8 isoform X1 [KO:K00939] [EC:2.7.4.3]
121309864  prune; exopolyphosphatase PRUNE1 [KO:K01514] [EC:3.6.1.11]
121309871  [KO:K01769] [EC:4.6.1.2]
121310831  entpd2a.1; ectonucleoside triphosphate diphosphohydrolase 2a.1 isoform X1 [KO:K01509] [EC:3.6.1.-]
121311801  [KO:K13755] [EC:3.1.4.17]
121312078  [KO:K00942] [EC:2.7.4.8]
121312752  [KO:K18532] [EC:2.7.4.3]
121312756  [KO:K13755] [EC:3.1.4.17]
121312845  guk1a; guanylate kinase isoform X1 [KO:K00942] [EC:2.7.4.8]
121313146  [KO:K08041] [EC:4.6.1.1]
121313195  [KO:K03783] [EC:2.4.2.1]
121313342  [KO:K00364] [EC:1.7.1.7]
121313384  [KO:K18436] [EC:3.1.4.53]
121313606  [KO:K18437] [EC:3.1.4.53]
121313620  [KO:K13298] [EC:3.1.4.17 3.1.4.35]
121313858  [KO:K01510] [EC:3.6.1.5]
121314012  pde11al; LOW QUALITY PROTEIN: dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A [KO:K13298] [EC:3.1.4.17 3.1.4.35]
121314215  [KO:K13755] [EC:3.1.4.17]
121314290  [KO:K00942] [EC:2.7.4.8]
121314330  [KO:K18436] [EC:3.1.4.53]
121314511  [KO:K08041] [EC:4.6.1.1]
121314788  [KO:K08042] [EC:4.6.1.1]
121314827  [KO:K00364] [EC:1.7.1.7]
121314890  [KO:K01513] [EC:3.1.4.1 3.6.1.9]
121314935  rrm2b; ribonucleoside-diphosphate reductase subunit M2 B [KO:K10808] [EC:1.17.4.1]
121314993  [KO:K03783] [EC:2.4.2.1]
121315396  [KO:K10808] [EC:1.17.4.1]
121315429  nt5e; 5'-nucleotidase [KO:K19970] [EC:3.1.3.5]
121315597  [KO:K01081] [EC:3.1.3.5]
121315626  [KO:K18424] [EC:3.6.1.29]
121315640  ak9; adenylate kinase 9 [KO:K18533] [EC:2.7.4.3 2.7.4.6]
121315642  [KO:K18438] [EC:3.1.4.17 3.1.4.35]
121315772  [KO:K01511] [EC:3.6.1.6]
121315869  [KO:K18436] [EC:3.1.4.53]
121315886  enpp1; ectonucleotide pyrophosphatase/phosphodiesterase family member 1 isoform X1 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
121315978  [KO:K12324] [EC:4.6.1.2]
121315990  xdh; xanthine dehydrogenase/oxidase [KO:K00106] [EC:1.17.1.4 1.17.3.2]
121316002  adcy3a; adenylate cyclase type 3 isoform X1 [KO:K08043] [EC:4.6.1.1]
121316059  [KO:K01939] [EC:6.3.4.4]
121316066  ntpcr; cancer-related nucleoside-triphosphatase isoform X1 [KO:K06928] [EC:3.6.1.15]
121316508  hddc2; HD domain-containing protein 2 [KO:K07023] [EC:3.1.3.89]
121316598  allc; allantoicase [KO:K01477] [EC:3.5.3.4]
121316721  [KO:K18438] [EC:3.1.4.17 3.1.4.35]
121316796  [KO:K13293] [EC:3.1.4.53]
121316873  [KO:K01511] [EC:3.6.1.6]
121316989  [KO:K18436] [EC:3.1.4.53]
121317006  [KO:K01513] [EC:3.1.4.1 3.6.1.9]
121317181  [KO:K01939] [EC:6.3.4.4]
121317359  nme6; nucleoside diphosphate kinase 6 [KO:K00940] [EC:2.7.4.6]
121317429  [KO:K18424] [EC:3.6.1.29]
121317453  [KO:K01081] [EC:3.1.3.5]
121317530  [KO:K10808] [EC:1.17.4.1]
121317614  [KO:K19970] [EC:3.1.3.5]
121317902  gc2; retinal guanylyl cyclase 2 [KO:K12322] [EC:4.6.1.2]
121317997  [KO:K19021] [EC:3.1.4.17]
121318183  [KO:K00088] [EC:1.1.1.205]
121318587  [KO:K19572] [EC:3.5.4.4]
121318738  [KO:K00948] [EC:2.7.6.1]
121318876  [KO:K00760] [EC:2.4.2.8]
121319097  [KO:K01487] [EC:3.5.4.3]
121319436  pnp4a; purine nucleoside phosphorylase 4a [KO:K03783] [EC:2.4.2.1]
121319768  [KO:K00944] [EC:2.7.4.10]
121319847  nudt5; ADP-sugar pyrophosphatase [KO:K13987] [EC:3.6.1.13 3.6.1.58 2.7.7.96]
121319901  [KO:K00088] [EC:1.1.1.205]
121320102  [KO:K19021] [EC:3.1.4.17]
121320173  [KO:K01587] [EC:4.1.1.21 6.3.2.6]
121320367  [KO:K18283] [EC:3.1.4.17]
121320369  [KO:K15779] [EC:5.4.2.2 5.4.2.7]
121320459  gucy1a2; guanylate cyclase soluble subunit alpha-2 isoform X1 [KO:K12318] [EC:4.6.1.2]
121320577  [KO:K00940] [EC:2.7.4.6]
121320650  [KO:K00948] [EC:2.7.6.1]
121320973  lacc1; purine nucleoside phosphorylase LACC1 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
121321000  [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
121321092  gucy1b2; guanylate cyclase soluble subunit beta-2 [KO:K12319] [EC:4.6.1.2]
121321145  gucy2f; retinal guanylyl cyclase 2 [KO:K12322] [EC:4.6.1.2]
121321439  [KO:K13755] [EC:3.1.4.17]
121321535  [KO:K01510] [EC:3.6.1.5]
121321624  [KO:K22600] [EC:4.6.1.2]
121321731  [KO:K01081] [EC:3.1.3.5]
121321805  [KO:K13811] [EC:2.7.7.4 2.7.1.25]
121321812  [KO:K00856] [EC:2.7.1.20]
121321955  [KO:K11265] [EC:4.6.1.1]
121322004  ppat; LOW QUALITY PROTEIN: amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
121322008  [KO:K13757] [EC:3.1.4.35]
121322226  [KO:K13298] [EC:3.1.4.17 3.1.4.35]
121322332  [KO:K00602] [EC:2.1.2.3 3.5.4.10]
121322490  [KO:K13811] [EC:2.7.7.4 2.7.1.25]
121322497  [KO:K13761] [EC:3.1.4.35]
121322506  [KO:K08045] [EC:4.6.1.1]
121322538  [KO:K00602] [EC:2.1.2.3 3.5.4.10]
121322545  [KO:K13298] [EC:3.1.4.17 3.1.4.35]
121322641  [KO:K13758]
121322700  pde5ab; cGMP-specific 3',5'-cyclic phosphodiesterase isoform X1 [KO:K13762] [EC:3.1.4.35]
121322959  [KO:K12318] [EC:4.6.1.2]
121322974  [KO:K08045] [EC:4.6.1.1]
121323248  [KO:K01951] [EC:6.3.5.2]
121323450  [KO:K12319] [EC:4.6.1.2]
121323547  [KO:K13755] [EC:3.1.4.17]
121323551  [KO:K01466] [EC:3.5.2.5]
121323861  pgm2; phosphoglucomutase-2 isoform X1 [KO:K15779] [EC:5.4.2.2 5.4.2.7]
121323913  [KO:K12324] [EC:4.6.1.2]
121324082  [KO:K01769] [EC:4.6.1.2]
121324157  zgc:110540; deoxynucleoside kinase [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
121324404  [KO:K00939] [EC:2.7.4.3]
121324610  [KO:K01939] [EC:6.3.4.4]
121324947  [KO:K01511] [EC:3.6.1.6]
121325129  [KO:K01081] [EC:3.1.3.5]
121325273  pnp6; purine nucleoside phosphorylase 6 [KO:K03783] [EC:2.4.2.1]
121325516  [KO:K08047] [EC:4.6.1.1]
121325779  [KO:K13811] [EC:2.7.7.4 2.7.1.25]
121325852  [KO:K22600] [EC:4.6.1.2]
121325967  entpd1; ectonucleoside triphosphate diphosphohydrolase 1 [KO:K01510] [EC:3.6.1.5]
121325975  [KO:K07127] [EC:3.5.2.17]
121326127  [KO:K00856] [EC:2.7.1.20]
121326183  [KO:K13757] [EC:3.1.4.35]
121326206  [KO:K00760] [EC:2.4.2.8]
121326356  [KO:K01835] [EC:5.4.2.2]
121326435  [KO:K12318] [EC:4.6.1.2]
121326523  [KO:K13758]
121326529  [KO:K12324] [EC:4.6.1.2]
121326556  [KO:K00939] [EC:2.7.4.3]
121326609  [KO:K12319] [EC:4.6.1.2]
121326746  pfas; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
121326752  [KO:K01587] [EC:4.1.1.21 6.3.2.6]
121327097  [KO:K13293] [EC:3.1.4.53]
121327392  [KO:K00939] [EC:2.7.4.3]
121327395  [KO:K01951] [EC:6.3.5.2]
121327756  [KO:K00940] [EC:2.7.4.6]
121327988  [KO:K00948] [EC:2.7.6.1]
121327997  [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
121328584  [KO:K13756] [EC:3.1.4.35]
121329068  zgc:103759; U8 snoRNA-decapping enzyme [KO:K16855] [EC:3.6.1.62 3.6.1.64]
121329317  [KO:K01522] [EC:3.6.1.29]
121329816  [KO:K01511] [EC:3.6.1.6]
121329848  [KO:K13296] [EC:3.1.4.17]
121329887  [KO:K01490] [EC:3.5.4.6]
121330211  [KO:K00939] [EC:2.7.4.3]
121330407  [KO:K01939] [EC:6.3.4.4]
121330462  [KO:K00939] [EC:2.7.4.3]
121330470  itpa; inosine triphosphate pyrophosphatase isoform X1 [KO:K01519] [EC:3.6.1.66]
121330489  [KO:K08049] [EC:4.6.1.1]
121330699  [KO:K12324] [EC:4.6.1.2]
121330861  [KO:K13759]
121330864  [KO:K13293] [EC:3.1.4.53]
121330991  [KO:K01081] [EC:3.1.3.5]
121331028  nme4; nucleoside diphosphate kinase, mitochondrial isoform X1 [KO:K00940] [EC:2.7.4.6]
121331074  [KO:K00939] [EC:2.7.4.3]
121331102  uox; uricase [KO:K00365] [EC:1.7.3.3]
121331178  [KO:K01835] [EC:5.4.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
pspa00030  Pentose phosphate pathway
pspa00220  Arginine biosynthesis
pspa00250  Alanine, aspartate and glutamate metabolism
pspa00260  Glycine, serine and threonine metabolism
pspa00340  Histidine metabolism
pspa00630  Glyoxylate and dicarboxylate metabolism
pspa00730  Thiamine metabolism
pspa00740  Riboflavin metabolism
pspa00790  Folate biosynthesis
KO pathway
ko00230   

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