KEGG Orthology (KO) - Acyrthosiphon pisum (pea aphid)

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     KO
 09100 Metabolism
 
   09101 Carbohydrate metabolism
 
   09102 Energy metabolism
 
   09103 Lipid metabolism
 
   09104 Nucleotide metabolism
     00230 Purine metabolism [PATH:api00230]
       100159385 ADP-ribose pyrophosphatase, mitochondrial
       100160293 phosphoglucomutase
       100163975 phosphoglucomutase-2
       100165332 uncharacterized protein LOC100165332
       100165626 ribose-phosphate pyrophosphokinase 2-like isoform X2
       100160599 amidophosphoribosyltransferase isoform X1
       100168774 LOW QUALITY PROTEIN: trifunctional purine biosynthetic protein adenosine-3
       100159986 Pfas; phosphoribosylformylglycinamidine synthase
       100169501 multifunctional protein ADE2
       100160523 adenylosuccinate lyase isoform X2
       100166999 adenylosuccinate lyase-like
       100168194 bifunctional purine biosynthesis protein PURH
       100161922 Adenine phosphoribosyltransferase-like
       100162276 uncharacterized protein LOC100162276
       100159257 uncharacterized protein LOC100159257 isoform X1
       100166892 cytosolic purine 5'-nucleotidase isoform X3
       100160663 protein 5NUC isoform X1
       100161212 protein 5NUC
       100162698 protein 5NUC isoform X1
       100164432 protein 5NUC
       100169565 protein 5NUC
       103309602 protein 5NUC-like
       103311672 protein 5NUC-like
       100163263 inosine-5'-monophosphate dehydrogenase
       100144800 Awd1; abnormal wing discs 1
       100144867 Awd2; abnormal wing discs 2
       100168200 nucleoside diphosphate kinase 6
       100165165 adenylate kinase 9-like
       100166504 apyrase-like
       103308894 soluble calcium-activated nucleotidase 1
       100162387 ectonucleoside triphosphate diphosphohydrolase 5
       100166838 uncharacterized protein LOC100166838 isoform X1
       100168402 Inosine triphosphate pyrophosphatase
       100169249 xanthine dehydrogenase
       100164487 bis(5'-nucleosyl)-tetraphosphatase
       100165217 GMP synthase [glutamine-hydrolyzing]
       100162173 Gmpr2; guanosine monophosphate reductase 2
       100164580 guanylate kinase isoform X1
       100161794 ribonucleoside-diphosphate reductase large subunit
       100162830 ribonucleoside-diphosphate reductase large subunit
       100166276 ribonucleoside-diphosphate reductase large subunit
       100569674 ribonucleoside-diphosphate reductase large subunit isoform X1
       100573189 ribonucleoside-diphosphate reductase large subunit
       107884892 ribonucleoside-diphosphate reductase large subunit-like
       100164872 ribonucleoside-diphosphate reductase subunit M2-like
       100165561 ribonucleoside-diphosphate reductase subunit M2
       100165338 thymidine kinase-like
       100165639 deoxynucleoside kinase
       100573648 deoxynucleoside kinase
       100164676 uncharacterized protein LOC100164676 isoform X1
       100164066 adenylate cyclase type 2
       100163190 adenylate cyclase type 3
       100160451 adenylate cyclase type 5 isoform X1
       100161699 adenylyl cyclase 78C isoform X1
       100167238 head-specific guanylate cyclase
       100160678 guanylate cyclase soluble subunit beta-1
       100167260 atrial natriuretic peptide receptor 1 isoform X1
       100160617 receptor-type guanylate cyclase Gyc76C isoform X1
       100163858 guanylate cyclase 32E
       100168799 soluble guanylate cyclase 89Db
       100168897 soluble guanylate cyclase 88E isoform X1
       100162857 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1 isoform X1
       100159334 retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta-like
       107884784 retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta-like
       100165174 cGMP-specific 3',5'-cyclic phosphodiesterase isoform X1
       100162827 dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
       100162869 dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 isoform X2
       100165684 adenylosuccinate synthetase
       100167425 AMP deaminase 2 isoform X5
       100162867 adenosine kinase-like
       100167522 adenosine kinase 2
       100161348 adenylate kinase isoenzyme 1
       100163893 Ak2; adenylate kinase 2, mitochondrial
       100165329 adenylate kinase isoenzyme 5
       100569374 uncharacterized protein LOC100569374 isoform X1
       103308028 adenylate kinase 7-like
       103308650 adenylate kinase 8-like
       100163917 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor-like
       100161031 GTP:AMP phosphotransferase AK3, mitochondrial isoform X1
       100160807 uncharacterized protein LOC100160807 isoform X1
       100166947 cAMP-specific 3',5'-cyclic phosphodiesterase isoform X3
       100162637 high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 isoform X1
       100168550 bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase isoform X2
       100571797 bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase-like
       100571805 bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1
       107882139 bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase-like
K13988 NUDT9; ADP-ribose diphosphatase [EC:3.6.1.13]
K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
K15779 PGM2; phosphoglucomutase / phosphopentomutase [EC:5.4.2.2 5.4.2.7]
K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
K11787 GART; phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1]
K01952 PFAS; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3]
K01587 PAICS; phosphoribosylaminoimidazole carboxylase / phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:4.1.1.21 6.3.2.6]
K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
K19970 NT5E; 5'-nucleotidase [EC:3.1.3.5]
K19970 NT5E; 5'-nucleotidase [EC:3.1.3.5]
K19970 NT5E; 5'-nucleotidase [EC:3.1.3.5]
K19970 NT5E; 5'-nucleotidase [EC:3.1.3.5]
K19970 NT5E; 5'-nucleotidase [EC:3.1.3.5]
K19970 NT5E; 5'-nucleotidase [EC:3.1.3.5]
K19970 NT5E; 5'-nucleotidase [EC:3.1.3.5]
K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K18533 AK9; adenylate/nucleoside-diphosphate kinase [EC:2.7.4.3 2.7.4.6]
K12304 CANT1; soluble calcium-activated nucleotidase 1 [EC:3.6.1.6]
K12304 CANT1; soluble calcium-activated nucleotidase 1 [EC:3.6.1.6]
K01511 ENTPD5_6; ectonucleoside triphosphate diphosphohydrolase 5/6 [EC:3.6.1.6]
K16855 NUDT16; U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64]
K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66]
K00106 XDH; xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2]
K01518 NUDT2; bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17]
K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
K00364 guaC; GMP reductase [EC:1.7.1.7]
K00942 gmk; guanylate kinase [EC:2.7.4.8]
K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K05961 dnk; deoxynucleoside kinase [EC:2.7.1.145]
K05961 dnk; deoxynucleoside kinase [EC:2.7.1.145]
K05961 dnk; deoxynucleoside kinase [EC:2.7.1.145]
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K12318 GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
K12319 GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
K12323 NPR1; atrial natriuretic peptide receptor 1 [EC:4.6.1.2]
K01769 E4.6.1.2; guanylate cyclase, other [EC:4.6.1.2]
K01769 E4.6.1.2; guanylate cyclase, other [EC:4.6.1.2]
K01769 E4.6.1.2; guanylate cyclase, other [EC:4.6.1.2]
K01769 E4.6.1.2; guanylate cyclase, other [EC:4.6.1.2]
K13755 PDE1; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17]
K13758 PDE6D; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
K13758 PDE6D; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
K13763 PDE6N; cGMP-specific 3',5'-cyclic phosphodiesterase, invertebrate [EC:3.1.4.35]
K13298 PDE11; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:3.1.4.17 3.1.4.35]
K13298 PDE11; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:3.1.4.17 3.1.4.35]
K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
K01490 AMPD; AMP deaminase [EC:3.5.4.6]
K00856 ADK; adenosine kinase [EC:2.7.1.20]
K00856 ADK; adenosine kinase [EC:2.7.1.20]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K18532 AK6; adenylate kinase [EC:2.7.4.3]
K00944 AK3; nucleoside-triphosphate--adenylate kinase [EC:2.7.4.10]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K18437 PDE8; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]
K13811 PAPSS; 3'-phosphoadenosine 5'-phosphosulfate synthase [EC:2.7.7.4 2.7.1.25]
K13811 PAPSS; 3'-phosphoadenosine 5'-phosphosulfate synthase [EC:2.7.7.4 2.7.1.25]
K13811 PAPSS; 3'-phosphoadenosine 5'-phosphosulfate synthase [EC:2.7.7.4 2.7.1.25]
K13811 PAPSS; 3'-phosphoadenosine 5'-phosphosulfate synthase [EC:2.7.7.4 2.7.1.25]
     00240 Pyrimidine metabolism [PATH:api00240]
 
   09105 Amino acid metabolism
 
   09106 Metabolism of other amino acids
 
   09107 Glycan biosynthesis and metabolism
 
   09108 Metabolism of cofactors and vitamins
 
   09109 Metabolism of terpenoids and polyketides
 
   09110 Biosynthesis of other secondary metabolites
 
   09111 Xenobiotics biodegradation and metabolism
 
   09112 Not included in regular maps
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
   09131 Membrane transport
 
   09132 Signal transduction
 
   09133 Signaling molecules and interaction
     04080 Neuroactive ligand-receptor interaction [PATH:api04080]
     04082 Neuroactive ligand signaling [PATH:api04082]
       100163208 guanine nucleotide-binding protein G(q) subunit alpha isoform X1
       100162131 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase isoform X2
       100166756 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II
       100161464 calcium-dependent protein kinase C isoform X3
       100159067 guanine nucleotide-binding protein G(s) subunit alpha
       100164676 uncharacterized protein LOC100164676 isoform X1
       100164066 adenylate cyclase type 2
       100163190 adenylate cyclase type 3
       100160451 adenylate cyclase type 5 isoform X1
       100161699 adenylyl cyclase 78C isoform X1
       100159120 cAMP-dependent protein kinase catalytic subunit 1
       100161173 cAMP-dependent protein kinase catalytic subunit alpha-like
       100163418 cAMP-dependent protein kinase catalytic subunit beta-like
       100164033 guanine nucleotide-binding protein G(i) subunit alpha
       100168757 Gnao1; guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
       100168225 guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
       100162789 guanine nucleotide-binding protein subunit beta-5
       100161117 guanine nucleotide-binding protein subunit gamma-e
       100160524 glutamate [NMDA] receptor subunit 1
       100167874 glutamate receptor ionotropic, NMDA 2B isoform X3
       100163143 glutamate receptor ionotropic, NMDA 3A isoform X1
       100159738 glutamate receptor 1
       100165752 excitatory amino acid transporter isoform X2
       100159935 excitatory amino acid transporter 1 isoform X1
       100159443 vesicular glutamate transporter 1
       100159630 vesicular glutamate transporter 1 isoform X1
       100168157 probable vesicular glutamate transporter eat-4 isoform X1
       100168565 vesicular glutamate transporter 2
       100168978 vesicular glutamate transporter 1 isoform X1
       100569641 probable vesicular glutamate transporter eat-4
       100570632 probable vesicular glutamate transporter eat-4
       100572677 probable vesicular glutamate transporter eat-4
       100574647 probable vesicular glutamate transporter eat-4
       100162087 gamma-aminobutyric acid type B receptor subunit 2
       100162583 gamma-aminobutyric acid type B receptor subunit 1
       100160775 gamma-aminobutyric acid receptor subunit beta isoform X1
       100165592 gamma-aminobutyric acid receptor subunit beta isoform X1
       100161653 sodium- and chloride-dependent GABA transporter 1
       100158713 amino acid transporter AVT1J isoform X2
       100161526 vesicular inhibitory amino acid transporter
       100169085 amino acid transporter AVT1D
       100162577 LOW QUALITY PROTEIN: glutamate-gated chloride channel alpha-like
       100169196 glycine receptor subunit alphaZ1-like
       100159916 muscarinic acetylcholine receptor M2
       100164141 muscarinic acetylcholine receptor DM1
       100168865 acetylcholinesterase
       100169250 acetylcholinesterase
       103308679 esterase E4
       100169284 high-affinity choline transporter 1
       100159222 choline O-acetyltransferase
       100166029 dopamine receptor 1-like
       100166556 dopamine D2-like receptor
       100162013 sodium-dependent dopamine transporter
       100161228 synaptic vesicular amine transporter isoform X2
       100163225 synaptic vesicular amine transporter
       100168249 5-hydroxytryptamine receptor 2B
       100575043 uncharacterized protein LOC100575043
       100575587 5-hydroxytryptamine receptor 1
       100159225 5-hydroxytryptamine receptor 2A-like
       100162110 sodium-dependent serotonin transporter
       100167910 sodium-dependent dopamine transporter-like
       100570822 adenosine receptor A2b-like
       100159754 tachykinin-like peptides receptor 86C isoform X1
       100161716 tachykinin-like peptides receptor 99D isoform X1
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO; guanine nucleotide-binding protein G(o) subunit alpha
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K05213 GRIN3A; glutamate receptor ionotropic, NMDA 3A
K05199 GRIA3; glutamate receptor 3
K05613 SLC1A2; solute carrier family 1 (glial high affinity glutamate transporter), member 2
K05614 SLC1A3; solute carrier family 1 (glial high affinity glutamate transporter), member 3
K12302 SLC17A6_7_8; MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6/7/8
K12302 SLC17A6_7_8; MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6/7/8
K12302 SLC17A6_7_8; MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6/7/8
K12302 SLC17A6_7_8; MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6/7/8
K12302 SLC17A6_7_8; MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6/7/8
K12302 SLC17A6_7_8; MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6/7/8
K12302 SLC17A6_7_8; MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6/7/8
K12302 SLC17A6_7_8; MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6/7/8
K12302 SLC17A6_7_8; MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6/7/8
K04615 GABBR; gamma-aminobutyric acid type B receptor
K04615 GABBR; gamma-aminobutyric acid type B receptor
K05181 GABRB; gamma-aminobutyric acid receptor subunit beta
K05181 GABRB; gamma-aminobutyric acid receptor subunit beta
K05034 SLC6A1; solute carrier family 6 (neurotransmitter transporter, GABA) member 1
K15015 SLC32A; solute carrier family 32 (vesicular inhibitory amino acid transporter)
K15015 SLC32A; solute carrier family 32 (vesicular inhibitory amino acid transporter)
K15015 SLC32A; solute carrier family 32 (vesicular inhibitory amino acid transporter)
K05195 GLRA3; glycine receptor alpha-3
K05195 GLRA3; glycine receptor alpha-3
K04131 CHRM3; muscarinic acetylcholine receptor M3
K04131 CHRM3; muscarinic acetylcholine receptor M3
K01049 ACHE; acetylcholinesterase [EC:3.1.1.7]
K01049 ACHE; acetylcholinesterase [EC:3.1.1.7]
K01049 ACHE; acetylcholinesterase [EC:3.1.1.7]
K14387 SLC5A7; solute carrier family 5 (high affinity choline transporter), member 7
K00623 CHAT; choline O-acetyltransferase [EC:2.3.1.6]
K04144 DRD1; dopamine receptor D1
K04145 DRD2; dopamine receptor D2
K05036 SLC6A3; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
K08155 SLC18A1_2; MFS transporter, DHA1 family, solute carrier family 18 (vesicular amine transporter), member 1/2
K08155 SLC18A1_2; MFS transporter, DHA1 family, solute carrier family 18 (vesicular amine transporter), member 1/2
K04157 HTR2; 5-hydroxytryptamine receptor 2
K04157 HTR2; 5-hydroxytryptamine receptor 2
K04163 HTR7; 5-hydroxytryptamine receptor 7
K04153 HTR1; 5-hydroxytryptamine receptor 1
K05037 SLC6A4; solute carrier family 6 (neurotransmitter transporter, serotonin) member 4
K05035 SLC6A2; solute carrier family 6 (neurotransmitter transporter, noradrenalin) member 2
K04266 ADORA2A; adenosine receptor A2a
K04224 TACR3; tachykinin receptor 3
K04224 TACR3; tachykinin receptor 3
     04081 Hormone signaling [PATH:api04081]
       100163208 guanine nucleotide-binding protein G(q) subunit alpha isoform X1
       100168225 guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
       100162789 guanine nucleotide-binding protein subunit beta-5
       100161117 guanine nucleotide-binding protein subunit gamma-e
       100162131 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase isoform X2
       100166756 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II
       100159067 guanine nucleotide-binding protein G(s) subunit alpha
       100164676 uncharacterized protein LOC100164676 isoform X1
       100164066 adenylate cyclase type 2
       100163190 adenylate cyclase type 3
       100160451 adenylate cyclase type 5 isoform X1
       100161699 adenylyl cyclase 78C isoform X1
       100159120 cAMP-dependent protein kinase catalytic subunit 1
       100161173 cAMP-dependent protein kinase catalytic subunit alpha-like
       100163418 cAMP-dependent protein kinase catalytic subunit beta-like
       100164033 guanine nucleotide-binding protein G(i) subunit alpha
       100168757 Gnao1; guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
       100166470 diuretic hormone receptor
       100572659 diuretic hormone receptor isoform X1
       100159283 G-protein coupled receptor-like
       100568898 orexin receptor type 2-like
       100570431 gastrin/cholecystokinin type B receptor-like
       100163512 lutropin-choriogonadotropic hormone receptor-like isoform X1
       100164576 lutropin-choriogonadotropic hormone receptor-like
       100167312 tyrosine-protein kinase hopscotch
       100161101 signal transducer and activator of transcription 5B isoform X3
       100162065 rap guanine nucleotide exchange factor 4
       100161392 Slc16a10; solute carrier family 16, member 10
       100160649 tyrosine-protein kinase Src64B
       100167260 atrial natriuretic peptide receptor 1 isoform X1
       100168151 cGMP-dependent protein kinase, isozyme 2 forms cD5/T2
       100166029 dopamine receptor 1-like
       100166556 dopamine D2-like receptor
       100160390 nitric oxide synthase, salivary gland isoform X1
       100169635 uncharacterized protein LOC100169635
       100569479 insulin receptor substrate 1 isoform X1
       100160001 phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
       100160876 phosphatidylinositol 3-kinase regulatory subunit gamma
       100164045 phosphatidylinositol 3-kinase regulatory subunit gamma
       100161832 insulin
       100568938 LIRP-like
       100570058 bombyxin B-8-like
       100574788 bombyxin C-1-like
       100575361 bombyxin C-2-like
       100169111 ecdysis triggering hormone receptor subtype-A
       100165181 guanine nucleotide-binding protein subunit alpha homolog isoform X1
       100160039 transforming protein Rho-like
       100162082 transforming protein Rho-like
       100165277 ras-like GTP-binding protein Rho1
       100169150 uncharacterized protein LOC100169150
       100167815 bone morphogenetic protein receptor type-1B
       100167170 protein mothers against dpp
       100169512 protein mothers against dpp
       100158948 mothers against decapentaplegic homolog 4 isoform X1
       100162614 mothers against decapentaplegic homolog 4
       100164543 mothers against decapentaplegic homolog 4-like
       100167677 mothers against decapentaplegic homolog 4-like
       100160637 uncharacterized protein LOC100160637
       100161609 serine/threonine-protein kinase STK11
       100161233 gonadotropin-releasing hormone receptor isoform X1
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO; guanine nucleotide-binding protein G(o) subunit alpha
K04578 CRHR1; corticotropin releasing hormone receptor 1
K04578 CRHR1; corticotropin releasing hormone receptor 1
K04314 PRLHR; prolactin releasing hormone receptor
K04239 HCRTR2; hypocretin (orexin) receptor 2
K04239 HCRTR2; hypocretin (orexin) receptor 2
K04249 TSHR; thyrotropin receptor
K04249 TSHR; thyrotropin receptor
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11224 STAT5B; signal transducer and activator of transcription 5B
K04351 RAPGEF4; Rap guanine nucleotide exchange factor 4
K08187 SLC16A10; MFS transporter, MCT family, solute carrier family 16 (monocarboxylic acid transporters), member 10
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K12323 NPR1; atrial natriuretic peptide receptor 1 [EC:4.6.1.2]
K07376 PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]
K04144 DRD1; dopamine receptor D1
K04145 DRD2; dopamine receptor D2
K13240 NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
K05459 IGF1; insulin-like growth factor 1
K16172 IRS1; insulin receptor substrate 1
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04526 INS; insulin
K04526 INS; insulin
K04526 INS; insulin
K04526 INS; insulin
K04526 INS; insulin
K04284 GHSR; growth hormone secretagogue receptor
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04513 RHOA; Ras homolog gene family, member A
K04513 RHOA; Ras homolog gene family, member A
K04513 RHOA; Ras homolog gene family, member A
K04675 ACVR1; activin receptor type-1 [EC:2.7.11.30]
K13578 BMPR1B; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
K04676 SMAD1; mothers against decapentaplegic homolog 1
K04676 SMAD1; mothers against decapentaplegic homolog 1
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04501 SMAD4; mothers against decapentaplegic homolog 4
K07297 ADIPOR; adiponectin receptor
K07298 STK11; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K28251 AkhR; adipokinetic hormone receptor
     04060 Cytokine-cytokine receptor interaction
     04061 Viral protein interaction with cytokine and cytokine receptor
     04512 ECM-receptor interaction [PATH:api04512]
     04514 Cell adhesion molecules
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
   09151 Immune system
 
   09152 Endocrine system
 
   09153 Circulatory system
 
   09154 Digestive system
 
   09155 Excretory system
 
   09156 Nervous system
 
   09157 Sensory system
 
   09158 Development and regeneration
 
   09149 Aging
     04211 Longevity regulating pathway
     04212 Longevity regulating pathway - worm
     04213 Longevity regulating pathway - multiple species [PATH:api04213]
       100161832 insulin
       100568938 LIRP-like
       100570058 bombyxin B-8-like
       100574788 bombyxin C-1-like
       100575361 bombyxin C-2-like
       100169635 uncharacterized protein LOC100169635
       100569479 insulin receptor substrate 1 isoform X1
       100159403 K-ras-like
       100160001 phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
       100160876 phosphatidylinositol 3-kinase regulatory subunit gamma
       100164045 phosphatidylinositol 3-kinase regulatory subunit gamma
       100160970 RAC serine/threonine-protein kinase
       100164676 uncharacterized protein LOC100164676 isoform X1
       100164066 adenylate cyclase type 2
       100163190 adenylate cyclase type 3
       100160451 adenylate cyclase type 5 isoform X1
       100161699 adenylyl cyclase 78C isoform X1
       100159120 cAMP-dependent protein kinase catalytic subunit 1
       100161173 cAMP-dependent protein kinase catalytic subunit alpha-like
       100163418 cAMP-dependent protein kinase catalytic subunit beta-like
       100168097 forkhead box protein O
       100164663 Superoxide dismutase [Mn], mitochondrial
       100159682 catalase
       100164879 Atg5; Autophagy-specific gene 5
       103309639 5'-AMP-activated protein kinase catalytic subunit alpha-2
       100166968 5'-AMP-activated protein kinase subunit beta-1
       100163481 serine/threonine-protein kinase mTOR
       100167375 regulatory-associated protein of mTOR isoform X1
       100162508 ribosomal protein S6 kinase beta-2
       100167327 NAD-dependent protein deacetylase sirtuin-1
       100162795 superoxide dismutase [Cu-Zn]-like precursor
       100166614 superoxide dismutase [Cu-Zn]-like
       100159065 heat shock 70 kDa protein cognate 4
       100160289 heat shock protein 70 A1-like
       100163748 heat shock 70 kDa protein cognate 4
       100167145 heat shock protein 68-like
       100168026 heat shock protein 70 B2
       100168413 heat shock protein 68-like
       100570349 heat shock protein 68-like
       100169331 protein lethal(2)essential for life
       100159920 histone deacetylase Rpd3-like
       100162023 histone deacetylase Rpd3
       100165220 histone deacetylase Rpd3-like isoform X1
       100167061 histone deacetylase Rpd3-like
       100569272 fork head domain-containing protein crocodile-like
       100166924 caseinolytic peptidase B protein homolog
       100169066 uncharacterized protein LOC100169066 isoform X2
K04526 INS; insulin
K04526 INS; insulin
K04526 INS; insulin
K04526 INS; insulin
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K16172 IRS1; insulin receptor substrate 1
K07827 KRAS; GTPase KRas
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K09408 FOXO3; forkhead box protein O3
K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
K03781 katE; catalase [EC:1.11.1.6]
K08339 ATG5; autophagy-related protein 5
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K11411 SIRT1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K04565 SOD1; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]
K04565 SOD1; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K09542 CRYAB; crystallin, alpha B
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K08035 FOXA2; forkhead box protein A2, hepatocyte nuclear factor 3-beta
K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB
 
 
   09159 Environmental adaptation
 
 09160 Human Diseases
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: July 9, 2025