KEGG   PATHWAY: acs00230
Entry
acs00230                    Pathway                                
Name
Purine metabolism - Anolis carolinensis (green anole)
Class
Metabolism; Nucleotide metabolism
Pathway map
acs00230  Purine metabolism
acs00230

Module
acs_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:acs00230]
acs_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:acs00230]
acs_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:acs00230]
acs_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:acs00230]
acs_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:acs00230]
acs_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:acs00230]
acs_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:acs00230]
Other DBs
GO: 0006163 0042278
Organism
Anolis carolinensis (green anole) [GN:acs]
Gene
100567262  nudt9; nudix hydrolase 9 [KO:K13988] [EC:3.6.1.13]
100557018  adprm; ADP-ribose/CDP-alcohol diphosphatase, manganese dependent [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
100567214  nudt5; nudix hydrolase 5 [KO:K13987] [EC:3.6.1.13 3.6.1.58 2.7.7.96]
100562877  pgm1; phosphoglucomutase 1 [KO:K01835] [EC:5.4.2.2]
100556533  pgm2; phosphoglucomutase 2 [KO:K15779] [EC:5.4.2.2 5.4.2.7]
100555631  prps1; phosphoribosyl pyrophosphate synthetase 1 [KO:K00948] [EC:2.7.6.1]
100556181  prps2; phosphoribosyl pyrophosphate synthetase 2 [KO:K00948] [EC:2.7.6.1]
100553317  ppat; phosphoribosyl pyrophosphate amidotransferase [KO:K00764] [EC:2.4.2.14]
100561300  gart; phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
100565628  trifunctional purine biosynthetic protein adenosine-3 [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
100559217  pfas; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
100566555  paics; phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01587] [EC:4.1.1.21 6.3.2.6]
100555996  adsl; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
100559178  atic; 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
100556354  aprt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
100556342  nt5c1a; 5'-nucleotidase, cytosolic IA [KO:K01081] [EC:3.1.3.5]
100557663  cytosolic 5'-nucleotidase 1B [KO:K01081] [EC:3.1.3.5]
100558071  nt5c; 5', 3'-nucleotidase, cytosolic [KO:K01081] [EC:3.1.3.5]
100559322  nt5c2; 5'-nucleotidase, cytosolic II [KO:K01081] [EC:3.1.3.5]
100568141  nt5m; 5',3'-nucleotidase, mitochondrial [KO:K01081] [EC:3.1.3.5]
100562128  cytosolic 5'-nucleotidase 1A [KO:K01081] [EC:3.1.3.5]
100560818  nt5e; 5'-nucleotidase ecto [KO:K19970] [EC:3.1.3.5]
100567275  pnp; purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
100563682  purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
100562047  lacc1; laccase domain containing 1 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
100555105  hprt1; hypoxanthine phosphoribosyltransferase 1 [KO:K00760] [EC:2.4.2.8]
100552361  impdh1; inosine monophosphate dehydrogenase 1 [KO:K00088] [EC:1.1.1.205]
100565151  inosine-5'-monophosphate dehydrogenase 2 [KO:K00088] [EC:1.1.1.205]
100561879  impdh2; inosine monophosphate dehydrogenase 2 [KO:K00088] [EC:1.1.1.205]
100559364  nme6; NME/NM23 nucleoside diphosphate kinase 6 [KO:K00940] [EC:2.7.4.6]
100561722  nme4; NME/NM23 nucleoside diphosphate kinase 4 [KO:K00940] [EC:2.7.4.6]
100567225  nme3; NME/NM23 nucleoside diphosphate kinase 3 [KO:K00940] [EC:2.7.4.6]
100562413  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
100562210  nucleoside diphosphate kinase A [KO:K00940] [EC:2.7.4.6]
100565822  nme7; NME/NM23 family member 7 [KO:K00940] [EC:2.7.4.6]
100563321  ak9; adenylate kinase 9 [KO:K18533] [EC:2.7.4.3 2.7.4.6]
103281931  entpd8; ectonucleoside triphosphate diphosphohydrolase 8 [KO:K01510] [EC:3.6.1.5]
100561052  entpd3; ectonucleoside triphosphate diphosphohydrolase 3 [KO:K01510] [EC:3.6.1.5]
100553564  entpd1; ectonucleoside triphosphate diphosphohydrolase 1 [KO:K01510] [EC:3.6.1.5]
100563392  cant1; calcium activated nucleotidase 1 [KO:K12304] [EC:3.6.1.6]
100562980  entpd4; ectonucleoside triphosphate diphosphohydrolase 4 [KO:K12305] [EC:3.6.1.6]
100555642  entpd5; ectonucleoside triphosphate diphosphohydrolase 5 [KO:K01511] [EC:3.6.1.6]
100561218  entpd6; ectonucleoside triphosphate diphosphohydrolase 6 (putative) [KO:K01511] [EC:3.6.1.6]
100563390  nudt16; nudix hydrolase 16 [KO:K16855] [EC:3.6.1.62 3.6.1.64]
100556854  itpa; inosine triphosphatase [KO:K01519] [EC:3.6.1.66]
100566790  xdh; xanthine dehydrogenase [KO:K00106] [EC:1.17.1.4 1.17.3.2]
100565132  nudt2; nudix hydrolase 2 [KO:K01518] [EC:3.6.1.17]
100567511  gmps; guanine monophosphate synthase [KO:K01951] [EC:6.3.5.2]
100555688  gmpr2; guanosine monophosphate reductase 2 [KO:K00364] [EC:1.7.1.7]
100563724  gmpr; guanosine monophosphate reductase [KO:K00364] [EC:1.7.1.7]
100562603  gda; guanine deaminase [KO:K01487] [EC:3.5.4.3]
100552465  guk1; guanylate kinase 1 [KO:K00942] [EC:2.7.4.8]
100562780  rrm1; ribonucleotide reductase catalytic subunit M1 [KO:K10807] [EC:1.17.4.1]
100566226  rrm2b; ribonucleotide reductase regulatory TP53 inducible subunit M2B [KO:K10808] [EC:1.17.4.1]
100568029  rrm2; ribonucleotide reductase regulatory subunit M2 [KO:K10808] [EC:1.17.4.1]
100562200  hddc2; HD domain containing 2 [KO:K07023] [EC:3.1.3.89]
100555629  dguok; deoxyguanosine kinase [KO:K00904] [EC:2.7.1.113]
100554557  dck; deoxycytidine kinase [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
100557346  deoxycytidine kinase [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
100559766  hddc3; HD domain containing 3 [KO:K21138] [EC:3.1.7.2]
100560554  prune1; prune exopolyphosphatase [KO:K01514] [EC:3.6.1.11]
100564004  adcy1; adenylate cyclase 1 [KO:K08041] [EC:4.6.1.1]
100555265  adcy2; adenylate cyclase 2 [KO:K08042] [EC:4.6.1.1]
100558229  adcy3; adenylate cyclase 3 [KO:K08043] [EC:4.6.1.1]
100562762  adcy4; adenylate cyclase 4 [KO:K08044] [EC:4.6.1.1]
100558125  adcy5; adenylate cyclase 5 [KO:K08045] [EC:4.6.1.1]
100558069  adcy6; adenylate cyclase 6 [KO:K08046] [EC:4.6.1.1]
100558751  adcy7; adenylate cyclase 7 [KO:K08047] [EC:4.6.1.1]
100556578  adcy8; adenylate cyclase 8 [KO:K08048] [EC:4.6.1.1]
100556223  adcy9; adenylate cyclase 9 [KO:K08049] [EC:4.6.1.1]
100551626  adcy10; adenylate cyclase 10, soluble [KO:K11265] [EC:4.6.1.1]
100563220  gucy1a3; guanylate cyclase 1 soluble subunit alpha [KO:K12318] [EC:4.6.1.2]
100554615  gucy1a2; guanylate cyclase 1 soluble subunit alpha 2 [KO:K12318] [EC:4.6.1.2]
100563021  gucy1b3; guanylate cyclase 1 soluble subunit beta [KO:K12319] [EC:4.6.1.2]
100565491  guanylate cyclase soluble subunit beta-2 [KO:K12319] [EC:4.6.1.2]
100563369  gucy2c; guanylate cyclase 2C [KO:K12320] [EC:4.6.1.2]
100558820  gucy2d; guanylate cyclase 2D, retinal [KO:K12321] [EC:4.6.1.2]
100556473  retinal guanylyl cyclase 2-like [KO:K12322] [EC:4.6.1.2]
100564400  guanylate cyclase 2G [KO:K22600] [EC:4.6.1.2]
100568215  npr2; natriuretic peptide receptor 2 [KO:K12324] [EC:4.6.1.2]
100566773  atrial natriuretic peptide receptor 1-like [KO:K12324] [EC:4.6.1.2]
100559800  pde1a; phosphodiesterase 1A [KO:K13755] [EC:3.1.4.17]
100555873  pde1b; phosphodiesterase 1B [KO:K13755] [EC:3.1.4.17]
100554993  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A [KO:K13755] [EC:3.1.4.17]
100556591  pde1c; phosphodiesterase 1C [KO:K13755] [EC:3.1.4.17]
103281257  cGMP-dependent 3',5'-cyclic phosphodiesterase [KO:K18283] [EC:3.1.4.17]
103281571  pde2a; phosphodiesterase 2A [KO:K18283] [EC:3.1.4.17]
100555208  pde3a; phosphodiesterase 3A [KO:K19021] [EC:3.1.4.17]
100556429  pde3b; phosphodiesterase 3B [KO:K13296] [EC:3.1.4.17]
100560459  pde5a; phosphodiesterase 5A [KO:K13762] [EC:3.1.4.35]
100560718  pde6b; phosphodiesterase 6B [KO:K13756] [EC:3.1.4.35]
100566240  pde6c; phosphodiesterase 6C [KO:K13757] [EC:3.1.4.35]
100564605  pde6d; phosphodiesterase 6D [KO:K13758]
100563391  pde6g; phosphodiesterase 6G [KO:K13759]
100553314  pde6h; phosphodiesterase 6H [KO:K13760]
100567129  pde9a; phosphodiesterase 9A [KO:K13761] [EC:3.1.4.35]
100561329  pde10a; phosphodiesterase 10A [KO:K18438] [EC:3.1.4.17 3.1.4.35]
100560285  pde11a; phosphodiesterase 11A [KO:K13298] [EC:3.1.4.17 3.1.4.35]
100554309  adss; adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
100556092  adssl1; adenylosuccinate synthase like 1 [KO:K01939] [EC:6.3.4.4]
100559571  ampd3; adenosine monophosphate deaminase 3 [KO:K01490] [EC:3.5.4.6]
100552392  ampd1; adenosine monophosphate deaminase 1 [KO:K01490] [EC:3.5.4.6]
100563338  ampd2; adenosine monophosphate deaminase 2 [KO:K01490] [EC:3.5.4.6]
100552795  adk; adenosine kinase [KO:K00856] [EC:2.7.1.20]
100561959  ada; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
100553844  cecr1; cat eye syndrome chromosome region, candidate 1 [KO:K19572] [EC:3.5.4.4]
100567665  ak5; adenylate kinase 5 [KO:K00939] [EC:2.7.4.3]
100560801  ak2; adenylate kinase 2 [KO:K00939] [EC:2.7.4.3]
100562329  ak7; adenylate kinase 7 [KO:K00939] [EC:2.7.4.3]
100561285  ak1; adenylate kinase 1 [KO:K00939] [EC:2.7.4.3]
100559423  ak8; adenylate kinase 8 [KO:K00939] [EC:2.7.4.3]
100555519  adenylate kinase isoenzyme 1 [KO:K00939] [EC:2.7.4.3]
100568108  ak4; adenylate kinase 4 [KO:K00939] [EC:2.7.4.3]
100558653  ak6; adenylate kinase 6 [KO:K18532] [EC:2.7.4.3]
100567310  ak3; adenylate kinase 3 [KO:K00944] [EC:2.7.4.10]
100561926  entpd2; ectonucleoside triphosphate diphosphohydrolase 2 [KO:K01509] [EC:3.6.1.-]
100565747  ntpcr; nucleoside-triphosphatase, cancer-related [KO:K06928] [EC:3.6.1.15]
100562470  enpp3; ectonucleotide pyrophosphatase/phosphodiesterase 3 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
100562666  enpp1; ectonucleotide pyrophosphatase/phosphodiesterase 1 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
100567896  pde4a; phosphodiesterase 4A [KO:K13293] [EC:3.1.4.53]
100558764  pde4b; phosphodiesterase 4B [KO:K13293] [EC:3.1.4.53]
100553294  pde4d; phosphodiesterase 4D [KO:K13293] [EC:3.1.4.53]
103281977  pde4c; phosphodiesterase 4C [KO:K13293] [EC:3.1.4.53]
100564782  pde7a; phosphodiesterase 7A [KO:K18436] [EC:3.1.4.53]
100565124  pde7b; phosphodiesterase 7B [KO:K18436] [EC:3.1.4.53]
100565292  pde8b; phosphodiesterase 8B [KO:K18437] [EC:3.1.4.53]
100557720  pde8a; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A [KO:K18437] [EC:3.1.4.53]
100559518  fhit; fragile histidine triad [KO:K01522] [EC:3.6.1.29]
100555583  enpp4; bis(5'-adenosyl)-triphosphatase ENPP4 [KO:K18424] [EC:3.6.1.29]
100555422  papss2; 3'-phosphoadenosine 5'-phosphosulfate synthase 2 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
100557387  papss1; 3'-phosphoadenosine 5'-phosphosulfate synthase 1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
100552598  uricase [KO:K00365] [EC:1.7.3.3]
100563501  5-hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
100559647  allantoinase, mitochondrial [KO:K01466] [EC:3.5.2.5]
100554640  allc; allantoicase [KO:K01477] [EC:3.5.3.4]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
acs00030  Pentose phosphate pathway
acs00220  Arginine biosynthesis
acs00250  Alanine, aspartate and glutamate metabolism
acs00260  Glycine, serine and threonine metabolism
acs00340  Histidine metabolism
acs00630  Glyoxylate and dicarboxylate metabolism
acs00730  Thiamine metabolism
acs00740  Riboflavin metabolism
acs00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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