KEGG   PATHWAY: dord04820
Entry
dord04820                   Pathway                                
Name
Cytoskeleton in muscle cells - Dipodomys ordii (Ord's kangaroo rat)
Class
Cellular Processes; Cell motility
Pathway map
dord04820  Cytoskeleton in muscle cells
dord04820

Organism
Dipodomys ordii (Ord's kangaroo rat) [GN:dord]
Gene
105980088  Itgb4; integrin beta-4 isoform X1 [KO:K06525]
105980215  Sgcb; beta-sarcoglycan [KO:K12566]
105980377  [KO:K21073]
105980381  Nid1; nidogen-1 [KO:K06826]
105980489  Itgb1; integrin beta-1 [KO:K05719]
105980943  Tln2; talin-2 [KO:K06271]
105981002  Sptbn5; spectrin beta chain, non-erythrocytic 5 [KO:K06115]
105981033  [KO:K12314]
105981061  Tmod2; tropomodulin-2 isoform X1 [KO:K10370]
105981112  Fbn1; fibrillin-1 [KO:K06825]
105981120  Tpm1; tropomyosin alpha-1 chain isoform X1 [KO:K10373]
105981135  Thbs1; thrombospondin-1 [KO:K16857]
105981156  Col4a4; collagen alpha-4(IV) chain [KO:K06237]
105981170  Capn3; calpain-3 isoform X1 [KO:K08573] [EC:3.4.22.54]
105981210  Tmod3; tropomodulin-3 [KO:K10370]
105981230  Fbln2; fibulin-2 [KO:K17307]
105981234  Tmem43; transmembrane protein 43 [KO:K27488]
105981274  [KO:K09290]
105981333  Lmod3; leiomodin-3 [KO:K22030]
105981494  Snta1; alpha-1-syntrophin [KO:K24063]
105981588  Tnnc2; troponin C, skeletal muscle [KO:K12042]
105981660  Sdc4; syndecan-4 [KO:K16338]
105981686  Diaph3; protein diaphanous homolog 3 [KO:K05745]
105981713  Myh7b; myosin-7B [KO:K24220]
105981786  Myl9; myosin regulatory light polypeptide 9 [KO:K12755]
105981975  Des; desmin [KO:K07610]
105982044  Mylpf; myosin regulatory light chain 2, skeletal muscle isoform [KO:K12758]
105982119  Myh11; myosin-11 isoform X1 [KO:K10352]
105982266  Col6a3; collagen alpha-3(VI) chain [KO:K06238]
105982338  Itga11; integrin alpha-11 [KO:K06587]
105982655  Nid2; nidogen-2 [KO:K06826]
105982839  Sdc2; syndecan-2 [KO:K16336]
105983029  Sntb2; LOW QUALITY PROTEIN: beta-2-syntrophin [KO:K24064]
105983277  Myh10; myosin-10 [KO:K10352]
105983300  Eno3; beta-enolase [KO:K01689] [EC:4.2.1.11]
105983325  Myh8; myosin-8 [KO:K24220]
105983326  Myh13; myosin-13 [KO:K24220]
105983327  [KO:K24220]
105983328  [KO:K24220]
105983329  [KO:K24220]
105983337  Myh3; myosin-3 [KO:K24220]
105983410  Atp1b2; sodium/potassium-transporting ATPase subunit beta-2 [KO:K01540]
105983605  Sdc1; syndecan-1 [KO:K06257]
105983653  Trim54; tripartite motif-containing protein 54 [KO:K10653]
105983779  Syne2; nesprin-2 [KO:K19346]
105984053  Agrn; agrin [KO:K06254]
105984402  [KO:K10354]
105984427  Vim; vimentin [KO:K07606]
105984520  Itga8; integrin alpha-8 [KO:K06584]
105984541  Nebl; nebulette isoform X1 [KO:K25865]
105984576  Dsg2; desmoglein-2 [KO:K07597]
105984580  Dsc2; desmocollin-2 [KO:K07601]
105984656  Dtna; dystrobrevin alpha isoform X1 [KO:K26998]
105984756  [KO:K10374]
105984769  Thbs3; thrombospondin-3 [KO:K04659]
105984792  Tmod4; tropomodulin-4 [KO:K10370]
105984919  Lmna; lamin [KO:K12641]
105985122  Fbn2; fibrillin-2 [KO:K23342]
105985127  Lmnb1; lamin-B1 [KO:K07611]
105985138  Atp1b1; sodium/potassium-transporting ATPase subunit beta-1 [KO:K01540]
105985162  Obscn; LOW QUALITY PROTEIN: obscurin [KO:K17531] [EC:2.7.11.1]
105985208  Fmn2; formin-2 [KO:K02184]
105985336  Thbs4; thrombospondin-4 [KO:K04659]
105985395  Vcan; versican core protein [KO:K06793]
105985456  Myot; myotilin [KO:K19875]
105985504  Pdlim7; PDZ and LIM domain protein 7 isoform X1 [KO:K19867]
105985971  Dsp; desmoplakin isoform X1 [KO:K10381]
105986071  Col9a2; collagen alpha-2(IX) chain [KO:K08131]
105986083  Daam1; disheveled-associated activator of morphogenesis 1 isoform X1 [KO:K04512]
105986140  Fhl3; four and a half LIM domains protein 3 [KO:K24414]
105986238  Mypn; myopalladin [KO:K22028]
105986313  Ank3; ankyrin-3 isoform X1 [KO:K09259]
105986436  Tnnt2; troponin T, cardiac muscle isoform X1 [KO:K12045]
105986451  Mybph; myosin-binding protein H isoform X1 [KO:K24494]
105986453  Lmod1; leiomodin-1 [KO:K22030]
105986473  Tnni1; troponin I, slow skeletal muscle [KO:K10371]
105986509  Csrp1; cysteine and glycine-rich protein 1 isoform X1 [KO:K09377]
105986527  Syne3; nesprin-3 [KO:K21761]
105986620  Nrap; nebulin-related-anchoring protein isoform X1 [KO:K24421]
105986628  Fn1; fibronectin [KO:K05717]
105986646  Pdlim1; PDZ and LIM domain protein 1 [KO:K23353]
105986710  Inf2; LOW QUALITY PROTEIN: inverted formin-2 [KO:K23958]
105986750  Ankrd2; ankyrin repeat domain-containing protein 2 isoform X1 [KO:K21434]
105986842  Sptbn1; spectrin beta chain, non-erythrocytic 1 isoform X1 [KO:K06115]
105986982  Atp1b4; protein ATP1B4 isoform X1 [KO:K01540]
105987022  Fhl1; four and a half LIM domains protein 1 isoform X1 [KO:K14365]
105987052  Col24a1; collagen alpha-1(XXIV) chain [KO:K19721]
105987066  Itga10; integrin alpha-10 [KO:K06586]
105987121  Itga7; integrin alpha-7 [KO:K06583]
105987295  Itga2; integrin alpha-2 [KO:K06481]
105987296  Itga1; integrin alpha-1 [KO:K06480]
105987432  Fmnl3; formin-like protein 3 [KO:K23957]
105987683  Mybpc1; myosin-binding protein C, slow-type [KO:K12557]
105987905  [KO:K06588]
105988085  Csrp3; cysteine and glycine-rich protein 3 isoform X1 [KO:K09377]
105988185  Ankrd23; ankyrin repeat domain-containing protein 23 [KO:K21438]
105988294  Col4a3; collagen alpha-3(IV) chain [KO:K06237]
105988327  Capza2; F-actin-capping protein subunit alpha-2 [KO:K10364]
105988337  Flnc; filamin-C isoform X1 [KO:K27393]
105988374  Lmod2; leiomodin-2 [KO:K22030]
105988723  Diaph1; protein diaphanous homolog 1 isoform X1 [KO:K05740]
105989048  Tnnt3; troponin T, fast skeletal muscle [KO:K12046]
105989160  Tnni2; troponin I, fast skeletal muscle [KO:K12043]
105989229  Sptbn2; spectrin beta chain, non-erythrocytic 2 isoform X1 [KO:K23932]
105989257  Actn3; alpha-actinin-3 isoform X1 [KO:K21073]
105989308  Sptan1; spectrin alpha chain, non-erythrocytic 1 [KO:K06114]
105989595  Zyx; zyxin [KO:K06273]
105990231  Lmnb2; lamin-B2 [KO:K07611]
105990335  Csrp2; cysteine and glycine-rich protein 2 [KO:K09377]
105990435  Col4a1; collagen alpha-1(IV) chain [KO:K06237]
105990449  Col4a2; collagen alpha-2(IV) chain [KO:K06237]
105990500  Dcn; decorin [KO:K04660]
105990664  Myl2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351]
105990826  Tmod1; tropomodulin-1 [KO:K10370]
105990935  Actb; actin, cytoplasmic 1 [KO:K05692]
105990948  Sun1; SUN domain-containing protein 1 isoform X1 [KO:K19347]
105991078  Eno2; gamma-enolase [KO:K01689] [EC:4.2.1.11]
105991143  Synpo2; synaptopodin-2 [KO:K24066]
105991192  Myoz2; myozenin-2 [KO:K26050]
105991217  Ank2; ankyrin-2 [KO:K09255]
105991352  Itgb8; integrin beta-8 [KO:K06591]
105991565  Myom2; myomesin-2 [KO:K24495]
105991784  Thbs2; thrombospondin-2 [KO:K04659]
105991915  Ampd1; AMP deaminase 1 isoform X1 [KO:K01490] [EC:3.5.4.6]
105991925  Atp1a1; sodium/potassium-transporting ATPase subunit alpha-1 [KO:K01539] [EC:7.2.2.13]
105991933  Capza1; F-actin-capping protein subunit alpha-1 [KO:K10364]
105992054  Myh9; myosin-9 [KO:K10352]
105992075  Sun2; SUN domain-containing protein 2 isoform X1 [KO:K19347]
105992210  Pdlim3; PDZ and LIM domain protein 3 [KO:K23353]
105992243  Sgcz; zeta-sarcoglycan [KO:K27062]
105992267  Capza3; F-actin-capping protein subunit alpha-3 [KO:K10364]
105992465  [KO:K17751]
105992471  Myh7; myosin-7 [KO:K17751]
105992563  Myoz3; myozenin-3 [KO:K26050]
105992655  Myoz1; myozenin-1 [KO:K26050]
105992664  Vcl; vinculin isoform X1 [KO:K05700]
105992702  Fbln1; fibulin-1 [KO:K17307]
105992792  Col4a6; collagen alpha-6(IV) chain [KO:K06237]
105992808  Col4a5; collagen alpha-5(IV) chain isoform X1 [KO:K06237]
105992946  Col1a2; collagen alpha-2(I) chain [KO:K06236]
105993370  Tln1; talin-1 isoform X1 [KO:K06271]
105993419  Tpm2; tropomyosin beta chain [KO:K10374]
105993437  [KO:K10366]
105993504  Lama2; laminin subunit alpha-2 [KO:K05637]
105993655  Syne1; nesprin-1 isoform X1 [KO:K19326]
105993774  Lama1; laminin subunit alpha-1 [KO:K05637]
105993794  Myom1; myomesin-1 [KO:K24495]
105993848  Neb; nebulin [KO:K18267]
105994005  Itga6; integrin alpha-6 [KO:K06485]
105994103  Ttn; titin [KO:K12567] [EC:2.7.11.1]
105994143  Col5a2; collagen alpha-2(V) chain [KO:K19721]
105994162  Mybpc2; myosin-binding protein C, fast-type [KO:K12558]
105994255  Myh14; myosin-14 [KO:K10352]
105994595  Dag1; dystroglycan [KO:K06265]
105994602  Col6a6; collagen alpha-6(VI) chain [KO:K06238]
105994691  Comp; cartilage oligomeric matrix protein [KO:K04659]
105994731  Tpm4; tropomyosin alpha-4 chain [KO:K10375]
105994862  Xirp2; xin actin-binding repeat-containing protein 2 [KO:K27381]
105994888  Myh15; myosin-15 [KO:K24220]
105995052  Ampd3; AMP deaminase 3 isoform X1 [KO:K01490] [EC:3.5.4.6]
105995125  Itga4; integrin alpha-4 [KO:K06483]
105995211  [KO:K01540]
105995249  Itgav; integrin alpha-V [KO:K06487]
105995606  Col5a1; collagen alpha-1(V) chain [KO:K19721]
105995778  Daam2; disheveled-associated activator of morphogenesis 2 [KO:K04512]
105995876  Pdlim5; PDZ and LIM domain protein 5 isoform X1 [KO:K19867]
105995971  Atp1b3; sodium/potassium-transporting ATPase subunit beta-3 [KO:K01540]
105996035  Mybpc3; myosin-binding protein C, cardiac-type [KO:K12568]
105996104  Col3a1; collagen alpha-1(III) chain [KO:K19720]
105996135  Col27a1; collagen alpha-1(XXVII) chain [KO:K19721]
105996168  Fmnl2; formin-like protein 2 isoform X1 [KO:K23957]
105996232  Xirp1; xin actin-binding repeat-containing protein 1 [KO:K27381]
105996264  Myl3; myosin light chain 3 [KO:K12749]
105996293  Itga9; integrin alpha-9 [KO:K06585]
105996309  Col9a3; collagen alpha-3(IX) chain [KO:K08131]
105996415  [KO:K01539] [EC:7.2.2.13]
105996530  Itgb6; integrin beta-6 isoform X1 [KO:K06589]
105996538  Atp1a2; sodium/potassium-transporting ATPase subunit alpha-2 [KO:K01539] [EC:7.2.2.13]
105996590  Tnnc1; troponin C, slow skeletal and cardiac muscles [KO:K05865]
105996737  Sgcd; delta-sarcoglycan [KO:K12563]
105997099  Col11a1; collagen alpha-1(XI) chain isoform X1 [KO:K19721]
105997452  Mybphl; myosin-binding protein H-like [KO:K24494]
105997472  Ampd2; AMP deaminase 2 isoform X1 [KO:K01490] [EC:3.5.4.6]
105997503  Itga2b; integrin alpha-IIb [KO:K06476]
105997562  Fmnl1; formin-like protein 1 isoform X1 [KO:K23957]
105997580  Ldb3; LIM domain-binding protein 3 [KO:K19867]
105997621  Sdc3; syndecan-3 [KO:K16337]
105997695  Sntb1; LOW QUALITY PROTEIN: beta-1-syntrophin [KO:K24064]
105997875  Myom3; myomesin-3 [KO:K24495]
105997942  Itgb7; integrin beta-7 [KO:K06590]
105997953  Itga5; integrin alpha-5 [KO:K06484]
105997956  Hspg2; basement membrane-specific heparan sulfate proteoglycan core protein [KO:K06255]
105998025  Sptbn4; spectrin beta chain, non-erythrocytic 4 [KO:K06115]
105998059  Ckm; creatine kinase M-type [KO:K27382]
105998060  Atp1a3; sodium/potassium-transporting ATPase subunit alpha-3 [KO:K01539] [EC:7.2.2.13]
105998236  Col6a1; collagen alpha-1(VI) chain [KO:K06238]
105998254  Col6a2; collagen alpha-2(VI) chain isoform X1 [KO:K06238]
105998282  Myl7; myosin regulatory light chain 2, atrial isoform isoform X1 [KO:K12754]
105998359  Trim63; E3 ubiquitin-protein ligase TRIM63 [KO:K10655] [EC:2.3.2.27]
105998427  Actg1; actin, cytoplasmic 2 [KO:K05692]
105998458  Eln; elastin [KO:K14211]
105998515  Myl1; myosin light chain 1/3, skeletal muscle isoform [KO:K05738]
105998521  Itgb3; integrin beta-3 [KO:K06493]
105998529  Myl4; myosin light chain 4 [KO:K12750]
105998623  Pkp2; plakophilin-2 [KO:K12642]
105998727  Fbn3; LOW QUALITY PROTEIN: fibrillin-3 [KO:K23342]
105998899  [KO:K28413]
105998921  Pdlim4; PDZ and LIM domain protein 4 [KO:K23353]
105998959  Diaph2; protein diaphanous homolog 2 [KO:K05741]
105999005  Plec; plectin isoform X1 [KO:K10388]
105999042  Col5a3; collagen alpha-3(V) chain [KO:K19721]
105999265  Capzb; F-actin-capping protein subunit beta [KO:K10365]
105999295  Eno1; alpha-enolase [KO:K01689] [EC:4.2.1.11]
105999371  Ankrd1; ankyrin repeat domain-containing protein 1 [KO:K21433]
105999406  Pdlim2; PDZ and LIM domain protein 2 [KO:K23353]
105999458  Trim55; tripartite motif-containing protein 55 isoform X1 [KO:K10654]
105999532  Tnnt1; troponin T, slow skeletal muscle isoform X1 [KO:K10372]
105999533  Tnni3; troponin I, cardiac muscle isoform X1 [KO:K12044]
105999578  Actg2; actin, gamma-enteric smooth muscle [KO:K12315]
105999627  Fhl2; four and a half LIM domains protein 2 [KO:K14380]
105999826  Col11a2; collagen alpha-2(XI) chain isoform X1 [KO:K19721]
106000099  Emd; emerin [KO:K12569]
106000116  Bgn; biglycan [KO:K08118]
106000591  Sgce; epsilon-sarcoglycan isoform X1 [KO:K27061]
106001119  Lbr; lamin-B receptor [KO:K19532] [EC:1.3.1.70]
106001588  Col9a1; collagen alpha-1(IX) chain [KO:K08131]
106001762  Sgca; alpha-sarcoglycan [KO:K12565]
106002220  [KO:K08118]
106002414  [KO:K09290]
106002774  [KO:K10364]
106003036  Tcap; telethonin [KO:K19879]
106003199  Sgcg; gamma-sarcoglycan [KO:K12564]
106003202  Itga3; integrin alpha-3 [KO:K06482]
106003238  Jup; junction plakoglobin isoform X1 [KO:K10056]
106003243  Col1a1; collagen alpha-1(I) chain [KO:K06236]
Reference
PMID:12142273
  Authors
Clark KA, McElhinny AS, Beckerle MC, Gregorio CC
  Title
Striated muscle cytoarchitecture: an intricate web of form and function.
  Journal
Annu Rev Cell Dev Biol 18:637-706 (2002)
DOI:10.1146/annurev.cellbio.18.012502.105840
Reference
PMID:31407867
  Authors
Mukund K, Subramaniam S
  Title
Skeletal muscle: A review of molecular structure and function, in health and disease.
  Journal
Wiley Interdiscip Rev Syst Biol Med 12:e1462 (2020)
DOI:10.1002/wsbm.1462
Reference
PMID:24481844
  Authors
Stroud MJ, Banerjee I, Veevers J, Chen J
  Title
Linker of nucleoskeleton and cytoskeleton complex proteins in cardiac structure, function, and disease.
  Journal
Circ Res 114:538-48 (2014)
DOI:10.1161/CIRCRESAHA.114.301236
Reference
PMID:28640448
  Authors
Henderson CA, Gomez CG, Novak SM, Mi-Mi L, Gregorio CC
  Title
Overview of the Muscle Cytoskeleton.
  Journal
Compr Physiol 7:891-944 (2017)
DOI:10.1002/cphy.c160033
Reference
PMID:32265741
  Authors
Csapo R, Gumpenberger M, Wessner B
  Title
Skeletal Muscle Extracellular Matrix - What Do We Know About Its Composition, Regulation, and Physiological Roles? A Narrative Review.
  Journal
Front Physiol 11:253 (2020)
DOI:10.3389/fphys.2020.00253
Reference
PMID:27114860
  Authors
Pinch M, Guth R, Samanta MP, Chaidez A, Unguez GA
  Title
The myogenic electric organ of Sternopygus macrurus: a non-contractile tissue with a skeletal muscle transcriptome.
  Journal
PeerJ 4:e1828 (2016)
DOI:10.7717/peerj.1828
Reference
PMID:23860255
  Authors
Sequeira V, Nijenkamp LL, Regan JA, van der Velden J
  Title
The physiological role of cardiac cytoskeleton and its alterations in heart failure.
  Journal
Biochim Biophys Acta 1838:700-22 (2014)
DOI:10.1016/j.bbamem.2013.07.011
Reference
PMID:36960155
  Authors
Zhang B, Powers JD, McCulloch AD, Chi NC
  Title
Nuclear mechanosignaling in striated muscle diseases.
  Journal
Front Physiol 14:1126111 (2023)
DOI:10.3389/fphys.2023.1126111
Reference
PMID:21464301
  Authors
Al-Amoudi A, Castano-Diez D, Devos DP, Russell RB, Johnson GT, Frangakis AS
  Title
The three-dimensional molecular structure of the desmosomal plaque.
  Journal
Proc Natl Acad Sci U S A 108:6480-5 (2011)
DOI:10.1073/pnas.1019469108
Reference
PMID:33067392
  Authors
Sikora M, Ermel UH, Seybold A, Kunz M, Calloni G, Reitz J, Vabulas RM, Hummer G, Frangakis AS
  Title
Desmosome architecture derived from molecular dynamics simulations and cryo-electron tomography.
  Journal
Proc Natl Acad Sci U S A 117:27132-27140 (2020)
DOI:10.1073/pnas.2004563117
Reference
PMID:26910421
  Authors
Xu XP, Kim E, Swift M, Smith JW, Volkmann N, Hanein D
  Title
Three-Dimensional Structures of Full-Length, Membrane-Embedded Human alpha(IIb)beta(3) Integrin Complexes.
  Journal
Biophys J 110:798-809 (2016)
DOI:10.1016/j.bpj.2016.01.016
Reference
PMID:22945352
  Authors
Wang W, Shi Z, Jiao S, Chen C, Wang H, Liu G, Wang Q, Zhao Y, Greene MI, Zhou Z
  Title
Structural insights into SUN-KASH complexes across the nuclear envelope.
  Journal
Cell Res 22:1440-52 (2012)
DOI:10.1038/cr.2012.126
Reference
PMID:23597672
  Authors
Sosa BA, Kutay U, Schwartz TU
  Title
Structural insights into LINC complexes.
  Journal
Curr Opin Struct Biol 23:285-91 (2013)
DOI:10.1016/j.sbi.2013.03.005
Reference
PMID:33058875
  Authors
Cruz VE, Esra Demircioglu F, Schwartz TU
  Title
Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes.
  Journal
J Mol Biol 432:6028-6041 (2020)
DOI:10.1016/j.jmb.2020.09.019
Reference
PMID:36523505
  Authors
Schuler SC, Liu Y, Dumontier S, Grandbois M, Le Moal E, Cornelison D, Bentzinger CF
  Title
Extracellular matrix: Brick and mortar in the skeletal muscle stem cell niche.
  Journal
Front Cell Dev Biol 10:1056523 (2022)
DOI:10.3389/fcell.2022.1056523
Reference
PMID:30425656
  Authors
Brull A, Morales Rodriguez B, Bonne G, Muchir A, Bertrand AT
  Title
The Pathogenesis and Therapies of Striated Muscle Laminopathies.
  Journal
Front Physiol 9:1533 (2018)
DOI:10.3389/fphys.2018.01533
Reference
PMID:36552829
  Authors
Storey EC, Fuller HR
  Title
Genotype-Phenotype Correlations in Human Diseases Caused by Mutations of LINC Complex-Associated Genes: A Systematic Review and Meta-Summary.
  Journal
Cells 11:cells11244065 (2022)
DOI:10.3390/cells11244065
Related
pathway
dord04512  ECM-receptor interaction
dord04814  Motor proteins
KO pathway
ko04820   

DBGET integrated database retrieval system