KEGG   PATHWAY: ajm00310
Entry
ajm00310                    Pathway                                
Name
Lysine degradation - Artibeus jamaicensis (Jamaican fruit-eating bat)
Class
Metabolism; Amino acid metabolism
Pathway map
ajm00310  Lysine degradation
ajm00310

Module
ajm_M00032  Lysine degradation, lysine => saccharopine => acetoacetyl-CoA [PATH:ajm00310]
Other DBs
GO: 0006554
Organism
Artibeus jamaicensis (Jamaican fruit-eating bat) [GN:ajm]
Gene
119046514  alpha-aminoadipic semialdehyde synthase, mitochondrial-like [KO:K14157] [EC:1.5.1.8 1.5.1.9]
119046515  alpha-aminoadipic semialdehyde synthase, mitochondrial-like isoform X1 [KO:K00293] [EC:1.5.1.10]
119044019  ALDH7A1; alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
119056569  AADAT; kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform X1 [KO:K00825] [EC:2.6.1.7 2.6.1.39]
119056684  DHTKD1; probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial isoform X1 [KO:K15791] [EC:1.2.4.-]
119036486  DLST; dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial isoform X1 [KO:K00658] [EC:2.3.1.61]
119054882  DLD; dihydrolipoyl dehydrogenase, mitochondrial isoform X1 [KO:K00382] [EC:1.8.1.4]
119048183  glutaryl-CoA dehydrogenase, mitochondrial-like [KO:K00252] [EC:1.3.8.6]
119049660  GCDH; glutaryl-CoA dehydrogenase, mitochondrial isoform X1 [KO:K00252] [EC:1.3.8.6]
119050402  HADHA; trifunctional enzyme subunit alpha, mitochondrial [KO:K07515] [EC:4.2.1.17 1.1.1.211]
119038747  EHHADH; peroxisomal bifunctional enzyme isoform X1 [KO:K07514] [EC:4.2.1.17 1.1.1.35 5.3.3.8]
119059533  ECHS1; enoyl-CoA hydratase, mitochondrial [KO:K07511] [EC:4.2.1.17]
119061439  HADH; hydroxyacyl-coenzyme A dehydrogenase, mitochondrial [KO:K00022] [EC:1.1.1.35]
119034913  ACAT2; acetyl-CoA acetyltransferase, cytosolic [KO:K00626] [EC:2.3.1.9]
119057264  HYKK; hydroxylysine kinase [KO:K18201] [EC:2.7.1.81]
119062952  PHYKPL; 5-phosphohydroxy-L-lysine phospho-lyase isoform X1 [KO:K18202] [EC:4.2.3.134]
119064872  succinate-semialdehyde dehydrogenase [NADP(+)]-like [KO:K00135] [EC:1.2.1.16 1.2.1.79 1.2.1.20]
119062029  PIPOX; peroxisomal sarcosine oxidase isoform X1 [KO:K00306] [EC:1.5.3.1 1.5.3.7]
119060921  CAMKMT; calmodulin-lysine N-methyltransferase isoform X1 [KO:K18826] [EC:2.1.1.60]
119050761  KMT2A; histone-lysine N-methyltransferase 2A isoform X1 [KO:K09186] [EC:2.1.1.354]
119042258  KMT2D; histone-lysine N-methyltransferase 2D isoform X1 [KO:K09187] [EC:2.1.1.354]
119039227  KMT2C; histone-lysine N-methyltransferase 2C [KO:K09188] [EC:2.1.1.354]
119044204  KMT2B; histone-lysine N-methyltransferase 2B [KO:K14959] [EC:2.1.1.354]
119063552  KMT2E; inactive histone-lysine N-methyltransferase 2E isoform X1 [KO:K09189] [EC:2.1.1.354]
119041139  SETD1A; histone-lysine N-methyltransferase SETD1A isoform X1 [KO:K11422] [EC:2.1.1.354]
119048615  SETD1B; histone-lysine N-methyltransferase SETD1B [KO:K11422] [EC:2.1.1.354]
119035000  SETD7; histone-lysine N-methyltransferase SETD7 [KO:K11431] [EC:2.1.1.364]
119035442  histone-lysine N-methyltransferase PRDM9-like [KO:K20796] [EC:2.1.1.354]
119036091  histone-lysine N-methyltransferase PRDM9-like [KO:K20796] [EC:2.1.1.354]
119036092  probable histone-lysine N-methyltransferase PRDM7 [KO:K20796] [EC:2.1.1.354]
119043644  histone-lysine N-methyltransferase PRDM9-like [KO:K20796] [EC:2.1.1.354]
119043757  probable histone-lysine N-methyltransferase PRDM7 [KO:K20796] [EC:2.1.1.354]
119037682  LOW QUALITY PROTEIN: histone-lysine N-methyltransferase PRDM9-like [KO:K20796] [EC:2.1.1.354]
119039771  LOW QUALITY PROTEIN: probable histone-lysine N-methyltransferase PRDM7 [KO:K20796] [EC:2.1.1.354]
119034582  LOW QUALITY PROTEIN: histone-lysine N-methyltransferase PRDM9-like [KO:K20796] [EC:2.1.1.354]
119034925  histone-lysine N-methyltransferase PRDM9-like isoform X1 [KO:K20796] [EC:2.1.1.354]
119051611  LOW QUALITY PROTEIN: probable histone-lysine N-methyltransferase PRDM7 [KO:K20796] [EC:2.1.1.354]
119051619  histone-lysine N-methyltransferase PRDM9-like [KO:K20796] [EC:2.1.1.354]
119059529  LOW QUALITY PROTEIN: histone-lysine N-methyltransferase PRDM9-like [KO:K20796] [EC:2.1.1.354]
119060370  histone-lysine N-methyltransferase PRDM9-like [KO:K20796] [EC:2.1.1.354]
119060949  LOW QUALITY PROTEIN: histone-lysine N-methyltransferase PRDM9-like [KO:K20796] [EC:2.1.1.354]
119060971  LOW QUALITY PROTEIN: probable histone-lysine N-methyltransferase PRDM7 [KO:K20796] [EC:2.1.1.354]
119060984  LOW QUALITY PROTEIN: histone-lysine N-methyltransferase PRDM9-like [KO:K20796] [EC:2.1.1.354]
119061031  probable histone-lysine N-methyltransferase PRDM7 [KO:K20796] [EC:2.1.1.354]
119053921  histone-lysine N-methyltransferase PRDM9-like [KO:K20796] [EC:2.1.1.354]
119061132  LOW QUALITY PROTEIN: histone-lysine N-methyltransferase PRDM9-like [KO:K20796] [EC:2.1.1.354]
119047144  PRDM7; LOW QUALITY PROTEIN: probable histone-lysine N-methyltransferase PRDM7 [KO:K20796] [EC:2.1.1.354]
119063186  histone-lysine N-methyltransferase PRDM9-like [KO:K20796] [EC:2.1.1.354]
119049357  histone-lysine N-methyltransferase PRDM9-like [KO:K20796] [EC:2.1.1.354]
119057248  histone-lysine N-methyltransferase PRDM9-like isoform X1 [KO:K20796] [EC:2.1.1.354]
119065815  histone-lysine N-methyltransferase PRDM9-like [KO:K20796] [EC:2.1.1.354]
119039727  ASH1L; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase ASH1L [KO:K06101] [EC:2.1.1.354]
119034511  SMYD1; histone-lysine N-methyltransferase SMYD1 [KO:K11426] [EC:2.1.1.354 2.1.1.357]
119053377  SMYD3; histone-lysine N-methyltransferase SMYD3 [KO:K11426] [EC:2.1.1.354 2.1.1.357]
119063144  SMYD2; N-lysine methyltransferase SMYD2 isoform X1 [KO:K11426] [EC:2.1.1.354 2.1.1.357]
119059808  SUV39H1; histone-lysine N-methyltransferase SUV39H1 [KO:K11419] [EC:2.1.1.355]
119046306  SUV39H2; histone-lysine N-methyltransferase SUV39H2 isoform X1 [KO:K11419] [EC:2.1.1.355]
119036154  EHMT1; histone-lysine N-methyltransferase EHMT1 [KO:K11420] [EC:2.1.1.355]
119053719  EHMT2; histone-lysine N-methyltransferase EHMT2 isoform X1 [KO:K11420] [EC:2.1.1.355]
119034734  SETDB1; histone-lysine N-methyltransferase SETDB1 isoform X1 [KO:K11421] [EC:2.1.1.366]
119056213  LOW QUALITY PROTEIN: histone-lysine N-methyltransferase SETDB2-like [KO:K18494] [EC:2.1.1.355]
119064074  PRDM2; PR domain zinc finger protein 2 isoform X1 [KO:K11432] [EC:2.1.1.355]
119051949  EZH1; histone-lysine N-methyltransferase EZH1 isoform X1 [KO:K17451] [EC:2.1.1.356]
119051022  EZH2; histone-lysine N-methyltransferase EZH2 [KO:K11430] [EC:2.1.1.356]
119036677  histone-lysine N-methyltransferase SETMAR [KO:K11433] [EC:2.1.1.357]
119035139  NSD1; histone-lysine N-methyltransferase, H3 lysine-36 specific isoform X1 [KO:K15588] [EC:2.1.1.357]
119035490  NSD2; histone-lysine N-methyltransferase NSD2 [KO:K11424] [EC:2.1.1.357]
119065038  NSD3; histone-lysine N-methyltransferase NSD3 isoform X1 [KO:K11425] [EC:2.1.1.370 2.1.1.371]
119037871  SETD2; histone-lysine N-methyltransferase SETD2 isoform X1 [KO:K11423] [EC:2.1.1.359]
119043705  DOT1L; histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1 [KO:K11427] [EC:2.1.1.360]
119060733  KMT5A; N-lysine methyltransferase KMT5A isoform X1 [KO:K11428] [EC:2.1.1.361]
119063966  PRDM6; putative histone-lysine N-methyltransferase PRDM6 [KO:K20795] [EC:2.1.1.361]
119041826  KMT5B; histone-lysine N-methyltransferase KMT5B isoform X1 [KO:K11429] [EC:2.1.1.362]
119059966  KMT5C; histone-lysine N-methyltransferase KMT5C [KO:K11429] [EC:2.1.1.362]
119043606  MECOM; histone-lysine N-methyltransferase MECOM isoform X1 [KO:K04462] [EC:2.1.1.367]
119050552  PRDM16; histone-lysine N-methyltransferase PRDM16 isoform X1 [KO:K22410] [EC:2.1.1.367]
119040455  ALDH2; aldehyde dehydrogenase, mitochondrial [KO:K00128] [EC:1.2.1.3]
119045915  ALDH1B1; LOW QUALITY PROTEIN: aldehyde dehydrogenase X, mitochondrial [KO:K00128] [EC:1.2.1.3]
119046009  ALDH16A1; aldehyde dehydrogenase family 16 member A1 [KO:K00128] [EC:1.2.1.3]
119046193  aldehyde dehydrogenase family 2 member B7, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
119053672  aldehyde dehydrogenase, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
119054297  aldehyde dehydrogenase family 2 member B7, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
119064287  ALDH3A2; aldehyde dehydrogenase family 3 member A2 [KO:K00128] [EC:1.2.1.3]
119065427  ALDH9A1; 4-trimethylaminobutyraldehyde dehydrogenase [KO:K00149] [EC:1.2.1.47 1.2.1.3]
119040125  BBOX1; gamma-butyrobetaine dioxygenase [KO:K00471] [EC:1.14.11.1]
119064098  PLOD1; procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 [KO:K00473] [EC:1.14.11.4]
119047057  PLOD2; procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 isoform X1 [KO:K13645] [EC:1.14.11.4]
119044717  PLOD3; multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [KO:K13646] [EC:1.14.11.4 2.4.1.50 2.4.1.66]
119046812  COLGALT1; procollagen galactosyltransferase 1 [KO:K11703] [EC:2.4.1.50]
119049624  COLGALT2; procollagen galactosyltransferase 2 [KO:K11703] [EC:2.4.1.50]
Compound
C00024  Acetyl-CoA
C00026  2-Oxoglutarate
C00037  Glycine
C00042  Succinate
C00047  L-Lysine
C00068  Thiamin diphosphate
C00136  Butanoyl-CoA
C00164  Acetoacetate
C00322  2-Oxoadipate
C00332  Acetoacetyl-CoA
C00408  L-Pipecolate
C00431  5-Aminopentanoate
C00449  N6-(L-1,3-Dicarboxypropyl)-L-lysine
C00450  (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate
C00487  Carnitine
C00489  Glutarate
C00527  Glutaryl-CoA
C00739  D-Lysine
C00877  Crotonoyl-CoA
C00956  L-2-Aminoadipate
C00990  5-Aminopentanamide
C01087  (R)-2-Hydroxyglutarate
C01142  (3S)-3,6-Diaminohexanoate
C01144  (S)-3-Hydroxybutanoyl-CoA
C01149  4-Trimethylammoniobutanal
C01181  4-Trimethylammoniobutanoate
C01186  (3S,5S)-3,5-Diaminohexanoate
C01211  Procollagen 5-hydroxy-L-lysine
C01259  (3S)-3-Hydroxy-N6,N6,N6-trimethyl-L-lysine
C01672  Cadaverine
C02188  Protein lysine
C02727  N6-Acetyl-L-lysine
C03087  5-Acetamidopentanoate
C03196  (S)-2-Hydroxyglutarate
C03239  6-Amino-2-oxohexanoate
C03273  5-Oxopentanoate
C03366  5-Phosphooxy-L-lysine
C03656  (S)-5-Amino-3-oxohexanoic acid
C03793  N6,N6,N6-Trimethyl-L-lysine
C04020  D-Lysopine
C04076  L-2-Aminoadipate 6-semialdehyde
C04092  Delta1-Piperideine-2-carboxylate
C04487  5-(D-Galactosyloxy)-L-lysine-procollagen
C05161  (2R,5S)-2,5-Diaminohexanoate
C05231  L-3-Aminobutyryl-CoA
C05544  Protein N6-methyl-L-lysine
C05545  Protein N6,N6-dimethyl-L-lysine
C05546  Protein N6,N6,N6-trimethyl-L-lysine
C05548  6-Acetamido-2-oxohexanoate
C05825  2-Amino-5-oxohexanoate
C06157  [Dihydrolipoyllysine-residue succinyltransferase] S-glutaryldihydrolipoyllysine
C12455  5-Aminopentanal
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16741  L-Hydroxylysine
C22667  4-Carboxy-1-hydroxybutyryl-ThPP
Reference
PMID:11802770
  Authors
Vaz FM, Wanders RJ.
  Title
Carnitine biosynthesis in mammals.
  Journal
Biochem J 361:417-29 (2002)
DOI:10.1042/bj3610417
Reference
PMID:1682209
  Authors
Large PJ, Robertson A.
  Title
The route of lysine breakdown in Candida tropicalis.
  Journal
FEMS Microbiol Lett 66:209-13 (1991)
DOI:10.1111/j.1574-6968.1990.tb03998.x
Related
pathway
ajm00020  Citrate cycle (TCA cycle)
ajm00300  Lysine biosynthesis
ajm00780  Biotin metabolism
KO pathway
ko00310   
LinkDB

DBGET integrated database retrieval system