KEGG ORTHOLOGY: K13138

ORTHOLOGY: K13138

Entry

K13138                      KO

Symbol

INTS1

Name

integrator complex subunit 1

Disease

H02535

Neurodevelopmental disorder with dysmorphic facies

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03041 Spliceosome
    K13138  INTS1; integrator complex subunit 1
Spliceosome [BR:ko03041]
Other splicing related proteins
  Proteins involved in snRNP biogenesis
   Integrator complex
    K13138  INTS1; integrator complex subunit 1

Genes

HSA:	26173(INTS1)

PTR:	107975668(INTS1)

PPS:	100970904(INTS1)

GGO:	101138220(INTS1)

PON:	100448904(INTS1)

NLE:	100595365(INTS1)

HMH:	116462875(INTS1)

MCC:	711947(INTS1)

MCF:	102140347(INTS1)

MTHB:

126950586

MNI:	105483488(INTS1)

CSAB:

103246881(INTS1)

CATY:

105571764(INTS1)

PANU:

101005339(INTS1)

TGE:	112620931(INTS1)

MLEU:

105537879(INTS1)

RRO:	104664948(INTS1)

RBB:	108543710(INTS1)

TFN:	117073514(INTS1)

PTEH:

111523725(INTS1)

CANG:

105522421(INTS1)

CJC:	100406164(INTS1)

SBQ:	101030722(INTS1)

CIMI:

108288984(INTS1)

CSYR:

103255418(INTS1)

MMUR:

105868424(INTS1)

LCAT:

123632554(INTS1)

PCOQ:

105806037(INTS1)

OGA:	100940955(INTS1)

MMU:	68510(Ints1)

MCAL:

110294299(Ints1)

MPAH:

110339186(Ints1)

RNO:	288514(Ints1)

MCOC:

116068657(Ints1)

ANU:	117697966(Ints1)

MUN:	110550683(Ints1)

CGE:	100764130(Ints1)

MAUA:

101828658(Ints1)

PROB:

127237245(Ints1)

PLEU:

114685108(Ints1) 114688647

MORG:

121446294(Ints1) 121465018

MFOT:

126514310

AAMP:

119825373(Ints1)

NGI:	103748687(Ints1)

HGL:	101706432(Ints1)

CPOC:

100736118(Ints1)

CCAN:

109691698(Ints1)

DORD:

105990975(Ints1)

DSP:	122113615(Ints1)

PLOP:

125339323(Ints1)

NCAR:

124970433

MMMA:

107155903(Ints1)

OCU:

103347544

TUP:	102480566(INTS1)

GVR:	103591732(INTS1)

CFA:	100685475(INTS1)

CLUD:

112640183(INTS1)

VVP:	112929297(INTS1)

VLG:	121487934(INTS1)

NPO:	129520001(INTS1)

AML:	100473808(INTS1)

UMR:	103670063(INTS1)

UAH:	113247726(INTS1)

UAR:	123802505(INTS1)

ELK:

111145695

LLV:

125091168

MPUF:

101690837(INTS1)

MNP:	132026422(INTS1)

MLK:	131819453(INTS1)

NVS:	122896131(INTS1)

ORO:	101366730(INTS1)

EJU:	114199937(INTS1)

ZCA:	113933326(INTS1)

MLX:	117999282(INTS1)

NSU:	110572006(INTS1)

LWW:	102739891(INTS1)

FCA:	101089564(INTS1)

PYU:	121017484(INTS1)

PBG:	122471207(INTS1)

PVIV:

125154703(INTS1)

LRUF:

124519170

PPAD:

109251053(INTS1)

PUC:

125928341

AJU:

106966517

HHV:	120227983(INTS1)

BTA:	790146(INTS1)

BOM:	102282777(INTS1)

BIU:	109578510(INTS1)

BBUB:

102416161(INTS1)

CHX:	102187588(INTS1)

OAS:	101114160(INTS1)

BTAX:

128067822(INTS1)

ODA:	120856497(INTS1)

CCAD:

122433219(INTS1)

MBEZ:

129545799(INTS1)

SSC:	100523779(INTS1)

CFR:	102508469(INTS1)

CBAI:

105078159(INTS1)

CDK:	105105863(INTS1)

VPC:	102528639(INTS1)

BACU:

103007646(INTS1)

BMUS:

118881053(INTS1)

LVE:	103068305(INTS1)

OOR:	101285171(INTS1)

DLE:	111169355(INTS1)

PCAD:

102987607(INTS1)

PSIU:

116740296(INTS1)

NASI:

112412052(INTS1)

ECB:	100053529(INTS1)

EPZ:	103564635(INTS1)

EAI:	106834765(INTS1)

MYB:	102255040(INTS1)

MYD:	102766927(INTS1)

MMYO:

118658244(INTS1)

MLF:	102422170(INTS1)

PKL:	118710960(INTS1)

EFUS:

103299205(INTS1)

MNA:	107537030(INTS1)

DRO:	112319676(INTS1)

SHON:

118995048(INTS1)

AJM:	119043777(INTS1)

PDIC:

114509339(INTS1)

PHAS:

123809273(INTS1)

MMF:	118615198(INTS1)

PPAM:

129070326(INTS1)

HAI:	109380219(INTS1)

RFQ:	117016705(INTS1)

PALE:

102896195(INTS1)

PGIG:

120613749(INTS1)

PVP:	105304471(INTS1)

RAY:	107497390(INTS1)

MJV:	108394659(INTS1)

TOD:	119241431(INTS1)

SARA:

101547356(INTS1)

SETR:

126030371(INTS1)

LAV:	100655005(INTS1)

TMU:

101343127

ETF:	101660368(INTS1)

DNM:	101423374(INTS1)

MDO:	100021404(INTS1)

GAS:	123234059(INTS1)

SHR:	100932767(INTS1)

AFZ:

127564036

PCW:	110200105(INTS1)

OAA:	100083149(INTS1)

GGA:	416461(INTS1)

PCOC:

116237363(INTS1)

MGP:	100548816(INTS1)

CJO:	107320756(INTS1)

TPAI:

128079291(INTS1)

LMUT:

125700513(INTS1)

NMEL:

110406139(INTS1)

APLA:

101804637(INTS1)

ACYG:

106033537(INTS1)

CATA:

118249228(INTS1)

AFUL:

116495175(INTS1)

TGU:	100223218(INTS1)

LSR:	110475496(INTS1)

SCAN:

103817865(INTS1)

PMOA:

120513178(INTS1)

OTC:	121334526(INTS1)

PRUF:

121350755(INTS1)

GFR:	102031770(INTS1)

FAB:	101821744(INTS1)

OMA:	130259301(INTS1)

PHI:	102101773(INTS1)

PMAJ:

107211316(INTS1)

CCAE:

111936278(INTS1)

CCW:	104685035(INTS1)

CBRC:

103615589(INTS1)

ETL:	114054770(INTS1)

ZAB:	102062301(INTS1)

ACHL:

103807623(INTS1)

SVG:	106862925(INTS1)

MMEA:

130581613(INTS1)

HRT:	120759810(INTS1)

FPG:	101915884(INTS1)

FCH:	102046083(INTS1)

CLV:	102084778(INTS1)

EGZ:	104128968(INTS1)

NNI:	104015078(INTS1)

PCRI:

104024183(INTS1)

PLET:

104620743(INTS1)

EHS:	104503065(INTS1)

PCAO:

104039646

ACUN:

113485764(INTS1)

TALA:

104367794(INTS1)

PADL:

103913566(INTS1)

AFOR:

103904986(INTS1)

ACHC:

115335615(INTS1)

HALD:

104323138(INTS1)

HLE:	104833709(INTS1)

AGEN:

126034166

GCL:

127022306

CCRI:

104167616(INTS1)

CSTI:

104549409(INTS1)

CMAC:

104476919(INTS1)

MUI:	104544020(INTS1)

BREG:

104629369(INTS1)

GSTE:

104255165(INTS1)

LDI:	104349769(INTS1)

MNB:	103768651(INTS1)

OHA:	104331229(INTS1)

NNT:	104404349(INTS1)

SHAB:

115606193(INTS1)

DPUB:

104307732(INTS1)

PGUU:

104457578(INTS1)

ACAR:

104529319(INTS1)

CPEA:

104393821(INTS1)

AVIT:

104278127(INTS1)

CVF:	104287371(INTS1)

RTD:	128913481(INTS1)

CUCA:

104065990(INTS1)

TEO:	104374115(INTS1)

BRHI:

104491708(INTS1)

AAM:	106491309(INTS1)

AROW:

112974285(INTS1)

NPD:	112959923(INTS1)

TGT:	104564820(INTS1)

DNE:	112992872(INTS1)

SCAM:

104153971(INTS1)

ASN:	102379706(INTS1)

AMJ:	102573206(INTS1)

CPOO:

109314735(INTS1)

GGN:	109294313(INTS1)

PSS:	102458726(INTS1)

CMY:	102934572(INTS1)

CCAY:

125644268(INTS1)

DCC:	119862324(INTS1)

CPIC:

101934583(INTS1)

TST:	117883810(INTS1)

CABI:

116832927(INTS1)

MRV:	120373602(INTS1)

ACS:	100553864(ints1)

ASAO:

132782139(INTS1)

PVT:

110084702

SUND:

121914360(INTS1)

PBI:	103050868(INTS1)

PMUR:

107290643(INTS1)

CTIG:

120310425(INTS1)

PGUT:

117679546(INTS1)

APRI:

131185267(INTS1)

PTEX:

113438976(INTS1)

VKO:	123025220(INTS1)

PMUA:

114583982(INTS1)

PRAF:

128401906(INTS1)

ZVI:	118092841(INTS1)

HCG:	128336502(INTS1)

GJA:	107118780(INTS1)

STOW:

125431013(INTS1)

EMC:	129338856(INTS1)

XLA:	108701560(ints1.L)

XTR:	100380131(ints1)

NPR:	108787536(INTS1)

RTEM:

120943415(INTS1)

BBUF:

121007489(INTS1)

BGAR:

122945788(INTS1)

MUO:	115475532(INTS1) 115476096

GSH:	117369379(INTS1)

DRE:	562131(ints1)

SRX:	107745594 107745599 107753377(ints1)

SANH:

107674580 107703394

SGH:	107572041 107581700(ints1)

CAUA:

113092127(ints1)

CGIB:

127952384

PTET:

122338779(ints1)

LROH:

127162711(ints1)

OMC:	131535876(ints1)

PPRM:

120481421(ints1)

RKG:	130095036(ints1)

MAMB:

125269856(ints1)

CIDE:

127509256

MASI:

127450173 127451616

TROS:

130561856(ints1)

TDW:	130426430(ints1)

MANU:

129432190(ints1)

IPU:

108257161

IFU:	128600422(ints1)

PHYP:

113536215(ints1)

SMEO:

124376151(ints1)

TFD:	113660390(ints1)

TVC:	132863851(ints1)

AMEX:

103021905(ints1)

CMAO:

118805739(ints1)

EEE:	113568040(ints1)

CHAR:

105890792(ints1)

TRU:	101066335(ints1)

TFS:	130514961(ints1)

TNG:	GSTEN00034442G001

LCO:	104918721(ints1)

NCC:

104956805

TBEN:

117492671(ints1)

CGOB:

115012387(ints1)

PGEO:

117450973(ints1)

GACU:

117548644(ints1)

EMAC:

134878454(ints1)

ELY:	117268577(ints1)

EFO:	125879442(ints1)

PLEP:

121956506(ints1)

SLUC:

116059492(ints1)

ECRA:

117958062(ints1)

ESP:	116703026(ints1)

PFLV:

114569348(ints1)

GAT:	120827849(ints1)

PPUG:

119220629(ints1)

AFB:	129098326(ints1)

CLUM:

117734705(ints1)

PSWI:

130188906(ints1)

MSAM:

119891869(ints1)

SCHU:

122868376(ints1)

CUD:	121529623(ints1)

ALAT:

119014683(ints1)

MZE:	101464317(ints1)

ONL:	100697402(ints1)

OAU:	116312503(ints1)

OLA:	100304460(ints1)

OML:	112146372(ints1)

CSAI:

133421648(ints1)

XMA:	102231752(ints1)

XCO:	114160044(ints1)

XHE:	116735630(ints1)

PRET:

103468672(ints1)

PFOR:

103143805(ints1)

PLAI:

106960500(ints1)

PMEI:

106904581(ints1)

GAF:	122821483(ints1)

PPRL:

129352532(ints1)

CVG:	107092802(ints1)

CTUL:

119778840(ints1)

GMU:	124863484 124865061

NFU:	107378419(ints1)

KMR:	108246149(ints1)

ALIM:

106528471(ints1)

NWH:	119421926(ints1)

AOCE:

111583173(ints1)

MCEP:

124998119(ints1)

CSEM:

103392627(ints1)

POV:	109634295(ints1)

SSEN:

122785184(ints1)

HHIP:

117766339(ints1)

HSP:	118123641(ints1)

SMAU:

118288974(ints1)

LCF:

108900652

SDU:	111217555(ints1)

SLAL:

111660534(ints1)

XGL:	120785586(ints1)

HCQ:	109513778(ints1)

SSCV:

125984016

SBIA:

133513918(ints1)

PEE:	133414714(ints1)

PTAO:

133465480(ints1)

BPEC:

110167246(ints1)

MALB:

109965954(ints1)

BSPL:

114860682(ints1)

SJO:	128379019(ints1)

SASA:

106595167 106595168 106595169 106601055 106607338

STRU:

115171160 115198468

OTW:	112225736 112246044

OMY:	110486305 110538240

OGO:	123999592 124015353

ONE:	115104174 115110318

OKI:	109893348 109893370

OKE:	118365299 118384154

SALP:

111980763 111981344

SNH:	120034131 120036377

CCLU:

121550628 121569540

ELS:	105013222(ints1)

SFM:	108929590(ints1)

PKI:	111836905(ints1)

AANG:

118216829(ints1)

LOC:	102697054(ints1)

PSPA:

121300772 121330946

ARUT:

117418518(ints1) 117431821

PSEX:

120541950(ints1)

LCM:	102367326(INTS1)

CMK:	103186595(ints1)

RTP:	109926708(ints1)

CPLA:

122560769(ints1)

HOC:	132825479(ints1)

LERI:

129706824(ints1)

PMRN:

116951558(INTS1)

LRJ:	133340550(INTS1)

BFO:

BBEL:

CIN:

SCLV:

SPU:	105436718 584770

LPIC:

129269492 129270499

APLC:

110989478

SKO:

102803904

DME:	Dmel_CG3173(IntS1)

DER:

6548120

DSE:

6613003

DSI:	Dsimw501_GD11823(Dsim_GD11823)

DYA:	Dyak_GE14364

DAN:

DSR:

DPO:

DPE:

DMN:	108158745 117189476

DWI:

6640413

DGR:

6559367

DMO:	Dmoj_GI20703

DAZ:

DNV:

DHE:

DVI:

CCAT:

BDR:

RZE:

AOQ:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

CQU:	CpipJ_CPIJ002633

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_212820

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:	113505000 113506717

OFU:

PGW:

CCRN:

API:

DNX:	107162025 107172533

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

MQU:	129000694 129000957

PHU:	Phum_PHUM274800

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_310202

DMK:

DPZ:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

HAZT:

EAF:

LSM:

TCF:

PPOI:

ISC:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

CEL:	CELE_C06A5.1(ints-1)

CBR:

CBG_22096

CRQ:	GCK72_001086

BMY:	BM_BM9787(Bma-inst-1)

LOA:	LOAG_18113

TSP:

Tsp_07442

HRO:	HELRODRAFT_182783

LGI:	LOTGIDRAFT_107278

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CVN:

CANU:

OED:

MYI:

PMAX:

MCAF:

MMER:

DPOL:

OBI:

OSN:

LAK:

SMM:	Smp_172720 Smp_210070

OVI:	T265_03337

EGL:

NVE:

EPA:

ATEN:

ADF:	107346031 107351161

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

TAD:	TRIADDRAFT_60509

AQU:

100635049

PPP:

112274712

SRE:	PTSG_02064

DDI:	DDB_G0285393(ints1)

DPP:	DICPUDRAFT_100030

DFA:	DFA_00854(ints1)

PTI:	PHATR_46895

FCY:	FRACYDRAFT_260853

TPS:	THAPSDRAFT_20681

PIF:	PITG_02016

PSOJ:

PHYSODRAFT_347536

SPAR:

SPRG_03977

GTT:	GUITHDRAFT_135658

NGR:	NAEGRDRAFT_53889

» show all

Reference

PMID:16239144

Authors

Baillat D, Hakimi MA, Naar AM, Shilatifard A, Cooch N, Shiekhattar R

Title

Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.

Journal

Cell 123:265-76 (2005)
DOI:10.1016/j.cell.2005.08.019

Sequence

[hsa:26173]

LinkDB

DBGET integrated database retrieval system