KEGG   PATHWAY: cdk04714
Entry
cdk04714                    Pathway                                
Name
Thermogenesis - Camelus dromedarius (Arabian camel)
Description
Thermogenesis is essential for warm-blooded animals, ensuring normal cellular and physiological function under conditions of environmental challenge. Thermogenesis in brown and beige adipose tissue is mainly controlled by norepinephrine, which is released from sympathetic nervous system in response to cold or dietary stimuli. The mitochondrial uncoupling protein 1 (UCP1) is responsible for the process whereby chemical energy is converted into heat in these adipocytes. Activation of these adipocytes leads to an increase in calorie consumption and is expected to improve overweight conditions, providing a potential strategy for treating obesity and its related metabolic disorders.
Class
Organismal Systems; Environmental adaptation
Pathway map
cdk04714  Thermogenesis
cdk04714

Other DBs
GO: 1990845
Organism
Camelus dromedarius (Arabian camel) [GN:cdk]
Gene
105089947  ADRB3; beta-3 adrenergic receptor [KO:K04143]
105095656  LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas [KO:K04632]
105095655  neuroendocrine secretory protein 55 [KO:K04632]
105095715  ADCY1; adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
105094039  ADCY2; LOW QUALITY PROTEIN: adenylate cyclase type 2 [KO:K08042] [EC:4.6.1.1]
105100030  ADCY3; adenylate cyclase type 3 isoform X5 [KO:K08043] [EC:4.6.1.1]
105102432  ADCY4; adenylate cyclase type 4 isoform X1 [KO:K08044] [EC:4.6.1.1]
105090284  ADCY5; LOW QUALITY PROTEIN: adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
105103816  ADCY6; adenylate cyclase type 6 isoform X1 [KO:K08046] [EC:4.6.1.1]
105097528  ADCY7; adenylate cyclase type 7 isoform X1 [KO:K08047] [EC:4.6.1.1]
105096450  ADCY8; adenylate cyclase type 8 isoform X2 [KO:K08048] [EC:4.6.1.1]
105099828  ADCY9; adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
105086742  adenylate cyclase type 10-like isoform X7 [KO:K11265] [EC:4.6.1.1]
105092727  ADCY10; adenylate cyclase type 10 [KO:K11265] [EC:4.6.1.1]
105095035  PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1 [KO:K04345] [EC:2.7.11.11]
105100776  cAMP-dependent protein kinase catalytic subunit alpha [KO:K04345] [EC:2.7.11.11]
105093562  CREB1; cyclic AMP-responsive element-binding protein 1 isoform X2 [KO:K05870]
105089327  CREB3L4; cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X1 [KO:K09048]
105106926  CREB3L1; cyclic AMP-responsive element-binding protein 3-like protein 1 [KO:K09048]
105105303  CREB3L3; cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1 [KO:K09048]
105091622  CREB3L2; cyclic AMP-responsive element-binding protein 3-like protein 2 [KO:K09048]
105102288  CREB3; cyclic AMP-responsive element-binding protein 3 [KO:K09048]
105095833  CREB5; cyclic AMP-responsive element-binding protein 5 isoform X1 [KO:K09047]
105104887  PRDM16; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase PRDM16 [KO:K22410] [EC:2.1.1.367]
105103864  ZNF516; LOW QUALITY PROTEIN: zinc finger protein 516 [KO:K22411]
105088880  KDM1A; LOW QUALITY PROTEIN: lysine-specific histone demethylase 1A [KO:K11450] [EC:1.14.99.66]
105088374  UCP1; mitochondrial brown fat uncoupling protein 1 [KO:K08769]
105091085  KDM3B; LOW QUALITY PROTEIN: lysine-specific demethylase 3B [KO:K15601] [EC:1.14.11.65]
105104170  KDM3A; lysine-specific demethylase 3A isoform X1 [KO:K15601] [EC:1.14.11.65]
105087618  SMARCA4; transcription activator BRG1 isoform X1 [KO:K11647] [EC:5.6.2.-]
105100269  SMARCA2; LOW QUALITY PROTEIN: probable global transcription activator SNF2L2 [KO:K11647] [EC:5.6.2.-]
105095207  SMARCB1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 isoform X1 [KO:K11648]
105103743  SMARCC1; LOW QUALITY PROTEIN: SWI/SNF complex subunit SMARCC1 [KO:K11649]
105086373  SMARCC2; LOW QUALITY PROTEIN: SWI/SNF complex subunit SMARCC2 [KO:K11649]
105098682  SMARCD3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 isoform X1 [KO:K11650]
105090402  SMARCD2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 isoform X1 [KO:K11650]
105097187  SMARCD1; LOW QUALITY PROTEIN: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 [KO:K11650]
105099014  SMARCE1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 isoform X1 [KO:K11651]
105105716  actin, cytoplasmic 2 [KO:K05692]
105104247  ACTB; actin, cytoplasmic 1 [KO:K05692]
116150665  actin, cytoplasmic 1-like [KO:K05692]
105104077  actin-like [KO:K05692]
105085923  ACTL6A; actin-like protein 6A [KO:K11340]
105088561  ACTL6B; actin-like protein 6B isoform X1 [KO:K11652]
105100945  ARID1B; LOW QUALITY PROTEIN: AT-rich interactive domain-containing protein 1B [KO:K11653]
105100693  ARID1A; AT-rich interactive domain-containing protein 1A isoform X1 [KO:K11653]
105096931  DPF1; zinc finger protein neuro-d4 isoform X1 [KO:K22198]
105086255  DPF3; zinc finger protein DPF3 isoform X1 [KO:K22198]
105093103  PPARG; peroxisome proliferator-activated receptor gamma isoform X1 [KO:K08530]
105092037  MAP3K5; mitogen-activated protein kinase kinase kinase 5 isoform X1 [KO:K04426] [EC:2.7.11.25]
105100607  MAP2K3; dual specificity mitogen-activated protein kinase kinase 3 isoform X2 [KO:K04432] [EC:2.7.12.2]
105101337  MAPK13; mitogen-activated protein kinase 13 isoform X2 [KO:K04441] [EC:2.7.11.24]
105101338  MAPK14; mitogen-activated protein kinase 14 isoform X1 [KO:K04441] [EC:2.7.11.24]
105090355  MAPK11; mitogen-activated protein kinase 11 [KO:K04441] [EC:2.7.11.24]
105090356  MAPK12; mitogen-activated protein kinase 12 isoform X1 [KO:K04441] [EC:2.7.11.24]
105098360  PPARGC1A; peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X2 [KO:K07202]
105097571  ATF2; cyclic AMP-dependent transcription factor ATF-2 [KO:K04450]
105105304  SIRT6; LOW QUALITY PROTEIN: NAD-dependent protein deacetylase sirtuin-6 [KO:K11416] [EC:2.3.1.286]
105102899  FGF21; fibroblast growth factor 21 [KO:K22429]
105094673  PLIN1; LOW QUALITY PROTEIN: perilipin-1 [KO:K08768]
105090211  LIPE; hormone-sensitive lipase isoform X1 [KO:K07188] [EC:3.1.1.79]
105105445  PNPLA2; patatin-like phospholipase domain-containing protein 2 isoform X1 [KO:K16816] [EC:3.1.1.3]
105090112  MGLL; monoglyceride lipase isoform X2 [KO:K01054] [EC:3.1.1.23]
105106940  PRKAA1; 5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X1 [KO:K07198] [EC:2.7.11.31]
105092817  PRKAA2; 5'-AMP-activated protein kinase catalytic subunit alpha-2 [KO:K07198] [EC:2.7.11.31]
105089467  PRKAB2; 5'-AMP-activated protein kinase subunit beta-2 isoform X1 [KO:K07199]
105104898  PRKAB1; 5'-AMP-activated protein kinase subunit beta-1 isoform X1 [KO:K07199]
105103784  PRKAG1; 5'-AMP-activated protein kinase subunit gamma-1 isoform X2 [KO:K07200]
105098685  PRKAG2; 5'-AMP-activated protein kinase subunit gamma-2 isoform X1 [KO:K07200]
105096091  PRKAG3; LOW QUALITY PROTEIN: 5'-AMP-activated protein kinase subunit gamma-3 [KO:K07200]
105093688  GCG; glucagon isoform X1 [KO:K05259]
105103388  BMP8A; bone morphogenetic protein 8A [KO:K16622]
105095542  CNR1; cannabinoid receptor 1 [KO:K04277]
105107036  NPPA; natriuretic peptide A precursor [KO:K12334]
105107037  NPPB; natriuretic peptide B precursor [KO:K12335]
105089423  NPR1; atrial natriuretic peptide receptor 1 isoform X3 [KO:K12323] [EC:4.6.1.2]
105085256  PRKG1; cGMP-dependent protein kinase 1 isoform X1 [KO:K07376] [EC:2.7.11.12]
105091814  PRKG2; cGMP-dependent protein kinase 2 [KO:K19477] [EC:2.7.11.12]
105089359  KLB; beta-klotho isoform X1 [KO:K22404]
105105270  FGFR1; fibroblast growth factor receptor 1 isoform X1 [KO:K04362] [EC:2.7.10.1]
105094380  FRS2; fibroblast growth factor receptor substrate 2 [KO:K12461]
105104642  GRB2; growth factor receptor-bound protein 2 [KO:K04364]
105091467  SOS2; LOW QUALITY PROTEIN: son of sevenless homolog 2 [KO:K03099]
105103654  SOS1; son of sevenless homolog 1 isoform X1 [KO:K03099]
105105427  HRAS; GTPase HRas isoform X1 [KO:K02833]
105100066  KRAS; GTPase KRas isoform X1 [KO:K07827]
105089630  NRAS; GTPase NRas [KO:K07828]
105095315  RPS6KA3; ribosomal protein S6 kinase alpha-3 isoform X1 [KO:K04373] [EC:2.7.11.1]
105097177  RPS6KA6; ribosomal protein S6 kinase alpha-6 isoform X1 [KO:K04373] [EC:2.7.11.1]
105086277  RPS6KA2; ribosomal protein S6 kinase alpha-2 isoform X1 [KO:K04373] [EC:2.7.11.1]
105100692  RPS6KA1; ribosomal protein S6 kinase alpha-1 isoform X1 [KO:K04373] [EC:2.7.11.1]
105085191  TSC1; hamartin isoform X1 [KO:K07206]
105099714  TSC2; LOW QUALITY PROTEIN: tuberin [KO:K07207]
105098696  RHEB; GTP-binding protein Rheb [KO:K07208]
105106263  RPTOR; regulatory-associated protein of mTOR isoform X1 [KO:K07204]
105107024  MTOR; serine/threonine-protein kinase mTOR isoform X1 [KO:K07203] [EC:2.7.11.1]
105099710  MLST8; target of rapamycin complex subunit LST8 [KO:K08266]
105100186  AKT1S1; proline-rich AKT1 substrate 1 isoform X5 [KO:K16184]
105097829  RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X1 [KO:K04688] [EC:2.7.11.1]
105104425  RPS6KB2; ribosomal protein S6 kinase beta-2 isoform X1 [KO:K04688] [EC:2.7.11.1]
105095942  RPS6; 40S ribosomal protein S6 [KO:K02991]
105084436  ACSL1; long-chain-fatty-acid--CoA ligase 1 isoform X1 [KO:K01897] [EC:6.2.1.3]
105106978  ACSL3; long-chain-fatty-acid--CoA ligase 3 [KO:K01897] [EC:6.2.1.3]
105090001  ACSL6; long-chain-fatty-acid--CoA ligase 6 isoform X1 [KO:K01897] [EC:6.2.1.3]
105093185  ACSL4; long-chain-fatty-acid--CoA ligase 4 isoform X1 [KO:K01897] [EC:6.2.1.3]
105091694  ACSL5; long-chain-fatty-acid--CoA ligase 5 [KO:K01897] [EC:6.2.1.3]
5618953  ND1; NADH dehydrogenase subunit 1 [KO:K03878] [EC:7.1.1.2]
5618961  ND2; NADH dehydrogenase subunit 2 [KO:K03879] [EC:7.1.1.2]
5618962  ND3; NADH dehydrogenase subunit 3 [KO:K03880] [EC:7.1.1.2]
5618958  ND4; NADH dehydrogenase subunit 4 [KO:K03881] [EC:7.1.1.2]
5618955  ND4L; NADH dehydrogenase subunit 4L [KO:K03882] [EC:7.1.1.2]
5618957  ND5; NADH dehydrogenase subunit 5 [KO:K03883] [EC:7.1.1.2]
5618963  ND6; NADH dehydrogenase subunit 6 [KO:K03884] [EC:7.1.1.2]
105099258  NDUFS1; NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial [KO:K03934] [EC:7.1.1.2]
105100106  NDUFS2; NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial [KO:K03935] [EC:7.1.1.2]
105106884  NDUFS3; NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial [KO:K03936] [EC:7.1.1.2]
105087155  NDUFS4; NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial isoform X1 [KO:K03937]
105090973  NDUFS5; NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 [KO:K03938]
105102170  NDUFS6; NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial [KO:K03939]
105104129  NDUFS7; NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial isoform X1 [KO:K03940] [EC:7.1.1.2]
105104408  NDUFS8; NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial isoform X1 [KO:K03941] [EC:7.1.1.2]
116147839  LOW QUALITY PROTEIN: NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial-like [KO:K03941] [EC:7.1.1.2]
116147841  LOW QUALITY PROTEIN: NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial-like [KO:K03941] [EC:7.1.1.2]
105104414  NDUFV1; NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial [KO:K03942] [EC:7.1.1.2]
105086491  NDUFV2; NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial [KO:K03943] [EC:7.1.1.2]
105105846  NDUFV3; NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial isoform X1 [KO:K03944]
105091110  LOW QUALITY PROTEIN: nucleolin 2-like [KO:K03944]
116150922  NDUFA1; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 [KO:K03945]
105098104  NDUFA2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 [KO:K03946]
105105514  NDUFA3; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 [KO:K03947]
105088698  NDUFA4; cytochrome c oxidase subunit NDUFA4 [KO:K03948]
105098308  NDUFA4L2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 [KO:K03948]
105085342  NDUFA5; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 [KO:K03949]
105091880  NDUFA6; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 [KO:K03950]
105087580  NDUFA7; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 [KO:K03951]
105104365  NDUFA8; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 isoform X2 [KO:K03952]
105091332  NDUFA9; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial [KO:K03953]
105105383  NDUFA10; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial [KO:K03954]
105094828  NDUFAB1; acyl carrier protein, mitochondrial [KO:K03955]
105091762  NDUFA11; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 [KO:K03956]
105097420  NDUFA12; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 [KO:K11352]
105103723  NDUFA13; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 [KO:K11353]
105096144  NDUFB1; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 [KO:K03957]
105096996  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 [KO:K03957]
105091662  NDUFB2; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial [KO:K03958]
105099177  NDUFB3; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 [KO:K03959]
105090315  NDUFB4; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 [KO:K03960]
105085920  NDUFB5; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial [KO:K03961]
105085566  NDUFB6; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 [KO:K03962]
105105974  NDUFB7; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 [KO:K03963]
105084324  NDUFB8; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial [KO:K03964]
105096438  NDUFB9; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 [KO:K03965]
105099726  NDUFB10; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 [KO:K03966]
105101950  NDUFB11; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial [KO:K11351]
105087084  NDUFC1; NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial [KO:K03967]
105097534  NDUFC2; NADH dehydrogenase [ubiquinone] 1 subunit C2 [KO:K03968]
105096856  NDUFAF1; complex I intermediate-associated protein 30, mitochondrial isoform X1 [KO:K18159]
105084731  NDUFAF2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 [KO:K18160]
105087833  NDUFAF3; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 isoform X1 [KO:K09008]
105092255  NDUFAF4; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 [KO:K18161]
105088314  NDUFAF5; arginine-hydroxylase NDUFAF5, mitochondrial isoform X1 [KO:K18162] [EC:2.1.1.-]
105085756  NDUFAF6; NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 isoform X1 [KO:K18163]
105103637  NDUFAF7; protein arginine methyltransferase NDUFAF7, mitochondrial [KO:K18164]
116157844  NDUFAF8; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8 [KO:K24726]
105102189  SDHA; succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial isoform X1 [KO:K00234] [EC:1.3.5.1]
105107079  SDHB; succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial [KO:K00235] [EC:1.3.5.1]
105100098  SDHC; succinate dehydrogenase cytochrome b560 subunit, mitochondrial isoform X1 [KO:K00236]
105094129  SDHD; succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial [KO:K00237]
105089357  cytochrome b-c1 complex subunit Rieske, mitochondrial isoform X1 [KO:K00411] [EC:7.1.1.8]
5618965  CYTB; cytochrome b [KO:K00412]
105105005  cytochrome c1, heme protein, mitochondrial [KO:K00413]
105087919  cytochrome b-c1 complex subunit 1, mitochondrial [KO:K00414]
105092293  cytochrome b-c1 complex subunit 2, mitochondrial isoform X1 [KO:K00415]
105092921  cytochrome b-c1 complex subunit 6, mitochondrial isoform X1 [KO:K00416]
105090575  cytochrome b-c1 complex subunit 7 [KO:K00417]
105090190  cytochrome b-c1 complex subunit 8 [KO:K00418]
105099458  cytochrome b-c1 complex subunit 9 [KO:K00419]
105106524  cytochrome b-c1 complex subunit 10 [KO:K00420]
5618956  COX1; cytochrome c oxidase subunit I [KO:K02256] [EC:7.1.1.9]
5618959  COX2; cytochrome c oxidase subunit II [KO:K02261]
5618954  COX3; cytochrome c oxidase subunit III [KO:K02262]
105098909  cytochrome c oxidase subunit 4 isoform 1, mitochondrial [KO:K02263]
105100820  cytochrome c oxidase subunit 4 isoform 2, mitochondrial isoform X1 [KO:K02263]
105092495  cytochrome c oxidase subunit 4 isoform 1, mitochondrial-like [KO:K02263]
105087250  cytochrome c oxidase subunit 5A, mitochondrial [KO:K02264]
105092680  cytochrome c oxidase subunit 5B, mitochondrial [KO:K02265]
105101997  cytochrome c oxidase subunit 6A1, mitochondrial [KO:K02266]
105089718  cytochrome c oxidase subunit 6A2, mitochondrial [KO:K02266]
105088048  cytochrome c oxidase subunit 6B1 [KO:K02267]
105098744  cytochrome c oxidase subunit 6B2 [KO:K02267]
105090541  cytochrome c oxidase subunit 6C [KO:K02268]
105088079  cytochrome c oxidase subunit 7A1, mitochondrial [KO:K02270]
105105462  cytochrome c oxidase subunit 7A2, mitochondrial [KO:K02270]
105103545  cytochrome c oxidase subunit 7A-related protein, mitochondrial [KO:K02270]
105096479  cytochrome c oxidase subunit 7B2, mitochondrial [KO:K02271]
105095562  cytochrome c oxidase subunit 7B, mitochondrial [KO:K02271]
116151966  cytochrome c oxidase subunit 7C, mitochondrial [KO:K02272]
116152083  cytochrome c oxidase subunit 8A, mitochondrial [KO:K02273]
105085098  protoheme IX farnesyltransferase, mitochondrial [KO:K02257] [EC:2.5.1.141]
105097781  cytochrome c oxidase assembly protein COX11, mitochondrial [KO:K02258]
105097184  cytochrome c oxidase assembly protein COX14 isoform X1 [KO:K18181]
105084307  cytochrome c oxidase assembly protein COX15 homolog [KO:K02259] [EC:1.17.99.9]
105086148  cytochrome c oxidase assembly protein COX16 homolog, mitochondrial isoform X1 [KO:K18182]
105090323  cytochrome c oxidase copper chaperone [KO:K02260]
105091261  cytochrome c oxidase assembly protein COX18, mitochondrial isoform X2 [KO:K17797]
105099462  cytochrome c oxidase assembly protein COX20, mitochondrial [KO:K18184]
105092326  cytochrome c oxidase assembly factor 1 homolog isoform X2 [KO:K18173]
105090477  cytochrome c oxidase assembly factor 3 homolog, mitochondrial [KO:K18175]
105096946  cytochrome c oxidase assembly factor 4 homolog, mitochondrial [KO:K18177]
105099795  cytochrome c oxidase assembly factor 5 isoform X2 [KO:K18178]
105090748  cytochrome c oxidase assembly factor 6 homolog [KO:K18179]
105092971  cytochrome c oxidase assembly factor 7 [KO:K18180]
105095183  ATP5F1A; ATP synthase subunit alpha, mitochondrial [KO:K02132]
105086351  ATP5F1B; ATP synthase subunit beta, mitochondrial [KO:K02133] [EC:7.1.2.2]
105091350  ATP5F1C; ATP synthase subunit gamma, mitochondrial isoform X1 [KO:K02136]
105104113  ATP5F1D; ATP synthase subunit delta, mitochondrial [KO:K02134]
116147347  ATP5F1E; ATP synthase subunit epsilon, mitochondrial [KO:K02135]
105089856  ATP5PO; ATP synthase subunit O, mitochondrial [KO:K02137]
5618964  ATP6; ATP synthase F0 subunit 6 [KO:K02126]
105102044  ATP5PB; ATP synthase F(0) complex subunit B1, mitochondrial [KO:K02127]
105094601  ATP5MC2; ATP synthase F(0) complex subunit C2, mitochondrial [KO:K02128]
105095776  ATP5MC1; ATP synthase F(0) complex subunit C1, mitochondrial [KO:K02128]
105097572  ATP5MC3; ATP synthase F(0) complex subunit C3, mitochondrial [KO:K02128]
105104626  ATP5PD; ATP synthase subunit d, mitochondrial [KO:K02138]
105099357  ATP5MF; ATP synthase subunit f, mitochondrial [KO:K02130]
105086808  ATP5PF; ATP synthase-coupling factor 6, mitochondrial isoform X1 [KO:K02131]
5618960  ATP8; ATP synthase F0 subunit 8 [KO:K02125]
105090204  ATP5MG; ATP synthase subunit g, mitochondrial [KO:K02140]
105090776  CPT2; carnitine O-palmitoyltransferase 2, mitochondrial isoform X1 [KO:K08766] [EC:2.3.1.21]
105087874  SLC25A20; mitochondrial carnitine/acylcarnitine carrier protein isoform X1 [KO:K15109]
105095364  SLC25A29; mitochondrial basic amino acids transporter isoform X3 [KO:K15109]
105104399  CPT1A; carnitine O-palmitoyltransferase 1, liver isoform isoform X1 [KO:K08765] [EC:2.3.1.21]
105106153  CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [KO:K19523] [EC:2.3.1.21]
105100195  CPT1C; carnitine O-palmitoyltransferase 1, brain isoform isoform X1 [KO:K19524] [EC:2.3.1.21]
Compound
C00002  ATP
C00004  NADH
C00008  ADP
C00010  CoA
C00024  Acetyl-CoA
C00040  Acyl-CoA
C00080  H+
C00116  Glycerol
C00162  Fatty acid
C00165  Diacylglycerol
C00318  L-Carnitine
C00422  Triacylglycerol
C00547  L-Noradrenaline
C00575  3',5'-Cyclic AMP
C00745  Nicotine
C00942  3',5'-Cyclic GMP
C00951  Estradiol-17beta
C01352  FADH2
C01885  1-Acylglycerol
C02301  O-Acylcarnitine
C02465  Triiodothyronine
C11695  Anandamide
C13856  2-Arachidonoylglycerol
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Nat Rev Mol Cell Biol 17:480-95 (2016)
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Nat Med 19:1252-63 (2013)
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FASEB J 28:5361-75 (2014)
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Mol Nutr Food Res 60:18-42 (2016)
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Trends Mol Med 21:571-9 (2015)
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Trends Endocrinol Metab 26:657-68 (2015)
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Positive and negative control of Ucp1 gene transcription and the role of beta-adrenergic signaling networks.
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Int J Obes (Lond) 34 Suppl 1:S28-33 (2010)
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Nat Commun 7:11158 (2016)
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  Title
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Nat Commun 6:7052 (2015)
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Mol Cell 57:235-46 (2015)
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Related
pathway
cdk00020  Citrate cycle (TCA cycle)
cdk00190  Oxidative phosphorylation
cdk04010  MAPK signaling pathway
cdk04022  cGMP-PKG signaling pathway
cdk04024  cAMP signaling pathway
cdk04150  mTOR signaling pathway
cdk04923  Regulation of lipolysis in adipocytes
KO pathway
ko04714   
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