KEGG ORTHOLOGY: K11799

ORTHOLOGY: K11799

Entry

K11799                      KO

Symbol

DCAF4

Name

DDB1- and CUL4-associated factor 4

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K11799  DCAF4; DDB1- and CUL4-associated factor 4
Ubiquitin system [BR:ko04121]
Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul4 complex
    Target recognizing subunit (DCAF)
     K11799  DCAF4; DDB1- and CUL4-associated factor 4

Genes

HSA:	138009(DCAF4L2) 26094(DCAF4) 285429(DCAF4L1)

PTR:	467501(DCAF4) 471182(DCAF4L1) 472811(DCAF4L2)

PPS:	100988230(DCAF4L1) 100995685(DCAF4) 134728367(DCAF4L2)

GGO:	101131652(DCAF4) 101151461(DCAF4L2) 101153921(DCAF4L1)

PON:	100440143(DCAF4) 100444810(DCAF4L1) 100445978(DCAF4L2)

PPYG:

129012587(DCAF4) 129034763(DCAF4L1) 129042546(DCAF4L2)

NLE:	100583622(DCAF4L2) 100583713(DCAF4) 100592276(DCAF4L1)

HMH:	116457031(DCAF4L1) 116484784(DCAF4) 116812672(DCAF4L2)

SSYN:

129464798(DCAF4L1) 129485840(DCAF4L2) 129487693(DCAF4)

MCC:	695007(DCAF4L2) 695337(DCAF4) 708457(DCAF4L1)

MCF:	102137684(DCAF4L2) 102142097(DCAF4L1) 102142275(DCAF4)

MTHB:

126955223 126959527 126961159

MNI:	105487708(DCAF4L1) 105494299(DCAF4) 105497294(DCAF4L2)

CSAB:

103229295(DCAF4) 103237090(DCAF4L2) 103246169(DCAF4L1)

CATY:

105572877(DCAF4L2) 105584815(DCAF4L1) 105599548(DCAF4)

PANU:

101004111(DCAF4L2) 101016548(DCAF4L1) 101027044(DCAF4)

TGE:	112624986(DCAF4L1) 112629057(DCAF4) 112630387(DCAF4L2)

MLEU:

105541861(DCAF4) 105545182(DCAF4L1) 105550319(DCAF4L2)

RRO:	104656151(DCAF4) 104668896(DCAF4L2) 104679317(DCAF4L1)

RBB:	108516980(DCAF4L1) 108536213(DCAF4) 108545005(DCAF4L2)

TFN:	117069382(DCAF4) 117079359(DCAF4L2) 117085321(DCAF4L1)

PTEH:

111520386(DCAF4) 111549715(DCAF4L2) 111550925(DCAF4L1)

CANG:

105508244(DCAF4L2) 105516758(DCAF4L1) 105517193(DCAF4)

CJC:	100402746 100403150(DCAF4L2) 100415558(DCAF4L1) 108587678

SBQ:	101028351(DCAF4L2) 101050069(DCAF4L1) 101053494(DCAF4)

CIMI:

108288610 108288712(DCAF4L2) 108304502(DCAF4) 108315550(DCAF4L1)

ANAN:

105707312(DCAF4) 105725869(DCAF4L2) 110569289(DCAF4L1)

CSYR:

103272110(DCAF4)

MMUR:

105858170(DCAF4)

LCAT:

123647192(DCAF4)

PCOQ:

105819772(DCAF4)

OGA:	100965774(DCAF4)

MMU:	73828(Dcaf4)

MCAL:

110306489(Dcaf4)

MPAH:

110324460(Dcaf4)

RNO:	362762(Dcaf4)

MCOC:

116081068(Dcaf4)

ANU:	117697487(Dcaf4)

ASYL:

127687160(Dcaf4)

MUN:	110558657(Dcaf4)

CGE:	100752324(Dcaf4)

MAUA:

101844384(Dcaf4)

PROB:

127230946(Dcaf4)

PLEU:

114698499(Dcaf4)

MORG:

121452549(Dcaf4)

MFOT:

126515146

AAMP:

119819493(Dcaf4)

NGI:	103747395(Dcaf4)

HGL:	101717702(Dcaf4)

CPOC:

100726951(Dcaf4)

CCAN:

109687108(Dcaf4)

DORD:

105986741(Dcaf4)

DSP:	122118852(Dcaf4)

PLOP:

125363239(Dcaf4)

NCAR:

124977779

MMMA:

107148819(Dcaf4)

ITI:	101970228(Dcaf4)

OCU:

100346822

OPI:	101534221(DCAF4)

TUP:	102491888(DCAF4)

GVR:	103599692(DCAF4)

CFA:	490767(DCAF4)

CLUD:

112657700(DCAF4)

VVP:	112927241(DCAF4)

VLG:	121493601(DCAF4)

NPO:	129496208(DCAF4)

AML:

100477217

UMR:	103671443(DCAF4)

UAH:	113270370(DCAF4)

UAR:	123799018(DCAF4)

ELK:

111148628

LLV:

125103963

MPUF:

101690085(DCAF4)

MNP:	132000199(DCAF4)

MLK:	131836908(DCAF4)

NVS:	122894417(DCAF4)

ORO:	101383570(DCAF4)

EJU:	114197091(DCAF4)

ZCA:	113909942(DCAF4)

MLX:	118002018(DCAF4)

NSU:	110571428(DCAF4)

LWW:

102726580

FCA:	101085984(DCAF4)

PYU:	121032008(DCAF4)

PCOO:

112855213(DCAF4)

PBG:	122469285(DCAF4)

PVIV:

125167813(DCAF4)

LRUF:

124512058

LGF:	123584060(DCAF4)

AJU:

106974451

PTG:	102967944(DCAF4)

PPAD:

109253786(DCAF4)

PUC:

125909370

PLEZ:

122222903(DCAF4)

HHV:	120222215(DCAF4)

BTA:	511629(DCAF4)

BOM:	102287799(DCAF4)

BIU:	109565315(DCAF4)

BBUB:

102394025(DCAF4)

BBIS:

105000103(DCAF4)

CHX:	102180857(DCAF4)

OAS:	101123126(DCAF4)

BTAX:

128053936(DCAF4)

CSUM:

138072734(DCAF4)

ODA:	120852744(DCAF4)

CCAD:

122443824(DCAF4)

MREE:

136172388(DCAF4)

OVR:	110148931(DCAF4)

MBEZ:

129563613(DCAF4)

SSC:	100155352(DCAF4)

CFR:	102508371(DCAF4)

CBAI:

105074814(DCAF4)

CDK:	105086135(DCAF4)

VPC:	102533103(DCAF4)

BACU:

103000668(DCAF4)

BMUS:

118890035(DCAF4)

LVE:	103068912(DCAF4)

OOR:	101272550(DCAF4)

LALB:

132514733(DCAF4)

DLE:	111170924(DCAF4)

PCAD:

102994982(DCAF4) 114483893

PSIU:

116749181(DCAF4)

NASI:

112394863(DCAF4)

ECB:	100050032(DCAF4)

EPZ:	103567879(DCAF4)

EAI:	106827720(DCAF4)

MYB:	102249224(DCAF4)

MYD:	102775038(DCAF4)

MMYO:

118657648(DCAF4)

MLF:	102434423(DCAF4)

MDT:	132231907(DCAF4)

MYUM:

139011706(DCAF4)

PKL:	118715683(DCAF4)

EFUS:

103283606(DCAF4)

MNA:	107533464(DCAF4)

DRO:	112311180(DCAF4)

SHON:

118976758(DCAF4)

AJM:	119036044(DCAF4)

PDIC:

114492386(DCAF4)

PHAS:

123808442(DCAF4)

MMF:	118633199(DCAF4)

PPAM:

129065919(DCAF4)

HAI:	109381518(DCAF4)

RFQ:	117022728(DCAF4)

PALE:

102882446(DCAF4)

PGIG:

120619471(DCAF4)

PVP:	105299259(DCAF4)

RAY:	107505008(DCAF4)

MJV:	108407313(DCAF4)

TOD:	119239260(DCAF4)

SARA:

101543319(DCAF4)

SFUM:

130041552(DCAF4)

SETR:

126004136(DCAF4)

LAV:

100669181

TMU:

101345340

ETF:	101647691(DCAF4)

DNM:	101435650(DCAF4)

MDO:	100024761(DCAF4)

GAS:	123237788(DCAF4)

SHR:	100919636(DCAF4)

AFZ:

127549537

PCW:	110208364(DCAF4)

TVP:	118830050(DCAF4)

PBRV:

138164366(DCAF4)

OAA:	100076699(DCAF4)

TACU:

119944603(DCAF4)

GGA:	423253(DCAF4)

PCOC:

116229250(DCAF4)

MGP:	100548750(DCAF4)

CJO:	107314865(DCAF4)

TPAI:

128086161(DCAF4)

LMUT:

125694572(DCAF4)

NMEL:

110401020(DCAF4)

APLA:

101803180(DCAF4)

ACYG:

106042514(DCAF4)

CATA:

118244748(DCAF4)

AFUL:

116489935(DCAF4)

TGU:	100223970(DCAF4)

LSR:	110472143(DCAF4)

SCAN:

103826627(DCAF4)

PMOA:

120500425(DCAF4)

OTC:	121334223(DCAF4)

PRUF:

121349551(DCAF4)

ATRC:

139590099(DCAF4)

GFR:	102031368(DCAF4)

FAB:	101809731(DCAF4)

OMA:	130254395(DCAF4)

PHI:	102111073(DCAF4)

PMAJ:

107205767(DCAF4)

CCAE:

111930261(DCAF4)

CCW:	104683319(DCAF4)

CBRC:

103620790(DCAF4)

ACOE:

138111538(DCAF4)

ETL:	114055474(DCAF4)

ZAB:	102066575(DCAF4)

ZLE:	135448146(DCAF4)

ACHL:

103809453(DCAF4)

SVG:	106849017(DCAF4)

MMEA:

130573849(DCAF4)

HRT:	120754343(DCAF4)

SATI:

136362613(DCAF4)

CCIC:

134045223(DCAF4)

FPG:	101921363(DCAF4)

FCH:	102051320(DCAF4)

CCRI:

104167159(DCAF4)

NNT:	104400308(DCAF4)

SHAB:

115606012(DCAF4)

ACUN:

113480309(DCAF4)

TALA:

104364244(DCAF4)

ACHC:

115333896(DCAF4)

HALD:

104311884(DCAF4)

HLE:	104831122(DCAF4)

AGEN:

126049277

HHAR:

128139622(DCAF4)

GCL:

127016901

CSTI:

104562699(DCAF4)

LDI:

104345720

MNB:

103778676

DPUB:

104300336(DCAF4)

PPUS:

135177268(DCAF4)

AVIT:

104275973(DCAF4)

BRHI:

104501341(DCAF4)

EGZ:	104132285(DCAF4)

NNI:	104020327(DCAF4)

PCRI:

104025876(DCAF4)

PCAO:

104047048(DCAF4)

PADL:

103912785(DCAF4)

AFOR:

103898892(DCAF4)

FGA:	104071359(DCAF4)

GSTE:

104252294(DCAF4)

CBOY:

140653220(DCAF4)

CLV:	102098821(DCAF4)

MUI:	104535313(DCAF4)

PGUU:

104470960(DCAF4)

PLET:

104620859(DCAF4L2)

EHS:	104504692(DCAF4)

CMAC:

104474767(DCAF4)

CUCA:

104061766(DCAF4)

TEO:	104376918(DCAF4)

BREG:

104633853(DCAF4)

OHA:	104328135(DCAF4)

ACAR:

104523178(DCAF4)

CPEA:

104390571(DCAF4)

CVF:	104284001(DCAF4)

RTD:	128908361(DCAF4)

CRID:

134514651(DCAF4)

AAM:	106498315(DCAF4)

AROW:

112972364(DCAF4)

NPD:	112946692(DCAF4)

TGT:	104565231(DCAF4)

DNE:	112980659(DCAF4)

SCAM:

104141211(DCAF4)

ASN:	102378386(DCAF4)

AMJ:	102559810(DCAF4)

CPOO:

109321439(DCAF4)

GGN:	109298822(DCAF4)

PSS:	102461417(DCAF4)

CMY:	102941923(DCAF4)

CCAY:

125639159(DCAF4)

DCC:	119857938(DCAF4)

CPIC:

101949102(DCAF4)

TST:	117876823(DCAF4)

CABI:

116825389(DCAF4)

MRV:	120403661(DCAF4)

ACS:	100552632(dcaf4)

ASAO:

132766935(DCAF4)

PVT:	110088094(DCAF4)

SUND:

121919053(DCAF4)

PBI:	103052359(DCAF4)

PMUR:

107294174(DCAF4)

CTIG:

120303565(DCAF4)

TSR:	106556912(DCAF4)

PGUT:

117665610(DCAF4)

APRI:

131187640(DCAF4)

PTEX:

113441936(DCAF4)

NSS:	113414282(DCAF4)

VKO:	123026735(DCAF4)

PMUA:

114594656(DCAF4)

PRAF:

128411851(DCAF4)

ZVI:	118083910(DCAF4)

HCG:	128339430(DCAF4)

GJA:	107117885(DCAF4)

STOW:

125426839(DCAF4)

EMC:	129324348(DCAF4)

XLA:	108699186(dcaf4.L)

XTR:	100488467(dcaf4)

NPR:	108791217(DCAF4)

RTEM:

120921152(DCAF4)

BBUF:

120982517(DCAF4)

BGAR:

122922127(DCAF4)

PWL:	138260445(DCAF4)

MUO:	115477443(DCAF4)

GSH:	117364236(DCAF4)

DRE:	110437968 393674(wdr21)

SRX:	107715145 107721261(dcaf4)

SANH:

107659175

SGH:	107562700 107602090

CCAR:

109077384 109084344(wdr21)

CAUA:

113063065 113120895

CGIB:

127938780 127972613 127984586

PTET:

122325403(wdr21)

LROH:

127183110(wdr21)

OMC:	131527204(wdr21)

PPRM:

120493727(wdr21)

RKG:	130089117(wdr21)

MAMB:

125277956(wdr21)

CIDE:

127502006

CERY:

137018996(wdr21)

MASI:

127456738

TROS:

130565835(wdr21)

TDW:	130434146(wdr21)

MANU:

129429811(wdr21)

PDAB:

135738000 135738796

IPU:	108257584(wdr21)

IFU:	128600926(wdr21)

PHYP:

113547651

SMEO:

124376992(wdr21)

TFD:	113658055(wdr21)

TVC:	132843043(wdr21)

CGAR:

128514976(wdr21)

NGRA:

132883114(wdr21)

TRN:	134320140(wdr21)

AMEX:

103030787(wdr21)

CMAO:

118815687(wdr21)

EEE:	113570186(dcaf4)

CHAR:

105889798(wdr21)

SPIL:

134097271(wdr21)

TRU:	101064649(dcaf4)

TFS:	130515859(wdr21)

TNG:	GSTEN00020700G001

LCO:	104929771(dcaf4)

TBEN:

117498387(wdr21)

CGOB:

115003744

PGEO:

117439450(wdr21)

GACU:

117554218(wdr21)

EMAC:

134876702(wdr21)

ELY:	117270895(wdr21)

EFO:	125897283(wdr21)

PLEP:

121955652(wdr21)

SLUC:

116066501(wdr21)

ECRA:

117961994(wdr21)

ESP:	116705802(dcaf4)

PFLV:

114573194(dcaf4)

GAT:	120808542(wdr21)

PPUG:

119194610(wdr21)

AFB:	129106963(wdr21)

CLUM:

117727022(wdr21)

PSWI:

130202229(wdr21)

CANA:

137785887(wdr21)

CVE:	137871214(wdr21)

MSAM:

119909185(wdr21)

SCHU:

122862910(wdr21)

CUD:	121521326(wdr21)

SPUL:

138584809(wdr21)

LMIX:

132985162(wdr21)

ALAT:

119012180(wdr21)

ASTR:

137613029(wdr21)

MZE:	101467952(dcaf4)

ONL:	100698294(dcaf4)

OAU:	116332271(wdr21)

OLA:	101168836(dcaf4)

OML:	112158423(wdr21)

CSAI:

133418711(wdr21)

XMA:	102234979(dcaf4)

XCO:	114158257(dcaf4)

XHE:	116733773(dcaf4)

PRET:

103457935(dcaf4)

PFOR:

103144185(dcaf4)

PLAI:

106960682(dcaf4)

PMEI:

106923207(dcaf4)

GAF:	122824936(wdr21)

PPRL:

129369078(wdr21)

CVG:	107088480(dcaf4)

CTUL:

119788673(wdr21)

GMU:	124881742(wdr21)

NFU:	107377986(dcaf4)

KMR:	108231860(wdr21)

ALIM:

106531806(dcaf4)

NWH:	119418111(wdr21)

AOCE:

111587286(wdr21)

EJA:	138203531(wdr21)

BFRE:

138630245(wdr21)

MCEP:

124999140(wdr21)

CSEM:

103380754(dcaf4)

POV:	109632480(dcaf4)

SSEN:

122784122(wdr21)

SSOE:

131443464(wdr21)

HHIP:

117758076(wdr21)

HSP:	118099647(wdr21)

PPLT:

128460038(wdr21)

SMAU:

118290234(wdr21)

LCF:	108896850(wdr21)

SDU:	111237639(dcaf4)

SLAL:

111672530(dcaf4)

XGL:	120788842(wdr21)

HCQ:	109513257(dcaf4)

SSCV:

125989934

SBIA:

133496425(wdr21)

PEE:	133416843(wdr21)

PTAO:

133468603(wdr21)

BPEC:

110155066(dcaf4)

ENY:	140356280(wdr21)

MALB:

109962162(dcaf4)

BSPL:

114849616(wdr21)

SJO:	128377396(wdr21)

SSCO:

133997152(wdr21)

GMH:	115534804(dcaf4)

SASA:

106571065(dcaf4)

STRU:

115184028(dcaf4)

OTW:

121846471

OMY:	110529291(wdr21)

OGO:	123990493(wdr21)

ONE:

115116058

OKI:	116376490(dcaf4)

OKE:	118380526(wdr21)

OMM:	135529356 135529650

OCLA:

139414901

SNH:

120039366

CCLU:

121552487(wdr21)

ELS:	105024341(dcaf4)

OEP:	134025500(wdr21)

SFM:	108930741(dcaf4)

PKI:

111844449

AANG:

118228830(wdr21)

AROT:

135257159(wdr21)

CCOG:

133129658(wdr21)

LOC:	102684403(dcaf4)

PSPA:

121324726 121330199

ARUT:

117422180 117424506

PSEX:

120518542(wdr21)

LCM:	102350895(DCAF4)

CMK:	103178479(wdr21)

RTP:	109927916(wdr21)

CPLA:

122554028

HOC:	132818060(wdr21)

LERI:

129700496(wdr21)

PMRN:

116948265(DCAF4)

LRJ:

BFO:

BBEL:

CIN:

SCLV:

SPU:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

SKO:

PFLL:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DFR:

CSCU:

CVS:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

CEL:	CELE_F47D12.9(F47D12.9)

CBR:

CBG_17459

CRQ:	GCK72_010754

NAI:	NECAME_10072

BMY:	BM_BM4181(Bm4181)

LOA:	LOAG_05518

HRO:	HELRODRAFT_168163

LGI:	LOTGIDRAFT_232438

PVUL:

PCAN:

LSAX:

BGT:

GAE:

HRF:

HRJ:	124254546 124278808

HASI:

HCRA:

CRG:

CANU:

CVN:

MYI:

PMAX:

AIRR:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

LLON:

NVE:

EPA:	110233390 110245751

ATEN:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_61224

ATH:

AT5G17370

ALY:

9307833

CRB:

17883025

CSAT:

104706030 104735775 104770039 104773164 104778767

EUS:	EUTSA_v10015915mg

BRP:

103851104

BNA:	106349381 106354415

BOE:

RSZ:

THJ:

CIT:

CIC:	CICLE_v10015389mg

PVY:

MINC:

TCC:

GRA:

GHI:	107922745 107941888

GAB:

108450465

HSYR:

120178001

DZI:	111298445 111308499

EGR:

104440597

RARG:

115755387

GMX:	100797740 100798753

GSJ:	114367007 114387082

PVU:

VRA:

VAR:

VUN:

VUM:

CCAJ:

APRC:

MTR:

TPRA:

CAM:

PSAT:

VVO:	131595164 131609040

ADU:	107483665 107483696

AIP:

107639092

AHF:	112742388 112794738 112796475

LANG:

109334807

PCIN:

129285296

QSA:	O6P43_013362

FVE:

101290845

AANS:

126786726

RCN:	112168221 112203264

PPER:

PMUM:

PAVI:

PDUL:

MDM:

MSYL:

PXB:

PCOX:

MNT:

CSAV:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

MEAN:

JCU:

HBR:

MESC:

POP:

PEU:

PALZ:

PNZ:

JRE:	108993889 109001247

CILL:

CAVE:

AGLU:

QSU:

QLO:

TWL:

VVI:

VRI:

SLY:

SPEN:

SOT:

SSTN:

SDUL:

CANN:

LBB:

NTA:	107761923 107832506

NSY:

NTO:

NAU:

INI:

ITR:

SIND:

EGT:

SSPL:

SMIL:

SHIS:

APAN:

HAN:

ECAD:

LSV:

CCAV:

DCR:	108197713 108216509 108224549

CSIN:

RVL:

AEW:

DLT:

BVG:

SOE:

CQI:	110681982 110695151

ATRI:

NNU:

MING:

TSS:

PSOM:

OSA:

OBR:

OGL:

BDI:

ATS:

TDC:	119354716 119363903

TAES:

123045107 123052943 123188855

TUA:

LPER:

LRD:

SBI:

ZMA:

MFLO:

SITA:

SVS:

PVIR:

PHAI:

PAUA:

PDA:

EGU:

MUS:

ZOF:

DCT:

PEQ:

AOF:

MSIN:

ACAK:

NCOL:

ATR:

CJF:

SMO:	SELMODRAFT_422538

PPP:

112283946

GSL:	Gasu_27060

YLI:	2912598(YALI2_E00213g)

SPO:	2541535(wdr21)

SOM:	SOMG_03580(wdr21)

CNE:

CNA04730

CNB:

CNBA4560

CNG:	CNAG_07364

CGI:	CGB_A5010C

CDEU:

CNBG_1419

CDEP:

91087964(L203_103754)

KMG:	30161151(I203_105528)

KNE:	92183869(IAR55_006611)

TMS:	TREMEDRAFT_59155

TASA:

A1Q1_06307

CCAC:

CcaHIS019_0403970(CcaverHIS019_0403970)

PPL:	POSPLDRAFT_101509 POSPLDRAFT_98963

TVS:	TRAVEDRAFT_46720

PCO:	PHACADRAFT_212242

SHS:	STEHIDRAFT_169008

HIR:	HETIRDRAFT_417710

ADL:	AURDEDRAFT_182538

FME:	FOMMEDRAFT_137223

GTR:	GLOTRDRAFT_49552

LBC:	LACBIDRAFT_309610

CCI:	CC1G_09039

E1B28_000591

SCM:	SCHCO_01138439(SCHCODRAFT_01138439)

CPUT:

CONPUDRAFT_82017

SLA:	SERLADRAFT_439356

RIE:	OCT59_025684

DDI:	DDB_G0288597

DPP:	DICPUDRAFT_83022

DFA:

ACAN:

SPAR:

Reference

PMID:16949367

Authors

Jin J, Arias EE, Chen J, Harper JW, Walter JC

Title

A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1.

Journal

Mol Cell 23:709-21 (2006)
DOI:10.1016/j.molcel.2006.08.010

Sequence

[hsa:26094]

LinkDB

DBGET integrated database retrieval system