KEGG   PATHWAY: caua04625
Entry
caua04625                   Pathway                                
Name
C-type lectin receptor signaling pathway - Carassius auratus (goldfish)
Description
C-type lectin receptors (CLRs) are a large superfamily of proteins characterized by the presence of one or more C-type lectin-like domains (CTLDs). CLRs function as pattern-recognition receptors (PRRs) for pathogen-derived ligands in dendric cells, macrophages, neutrophils, etc., such as Dectin-1 and Dectin-2 for recognition of fungi-derived B-glucan and high mannose-type carbohydrates. Upon ligand binding, CLRs stimulate intracellular signaling cascades that induce the production of inflammatory cytokines and chemokines, consequently triggering innate and adaptive immunity to pathogens.
Class
Organismal Systems; Immune system
Pathway map
caua04625  C-type lectin receptor signaling pathway
caua04625

Organism
Carassius auratus (goldfish) [GN:caua]
Gene
113106249  GTPase HRas [KO:K02833]
113067303  GTPase HRas-like [KO:K02833]
113043599  GTPase HRas-like [KO:K02833]
113051345  GTPase HRas-like [KO:K02833]
113067076  ras-like protein isoform X1 [KO:K07827]
113043474  GTPase HRas-like [KO:K07827]
113043560  GTPase KRas [KO:K07827]
113046915  GTPase HRas-like [KO:K07827]
113106980  GTPase NRas-like [KO:K07828]
113071752  GTPase NRas [KO:K07828]
113083541  GTPase NRas-like [KO:K07828]
113076076  ras-related protein M-Ras isoform X1 [KO:K07831]
113077641  ras-related protein M-Ras-like [KO:K07831]
113108673  ras-related protein M-Ras isoform X1 [KO:K07831]
113099721  ras-related protein M-Ras-like [KO:K07831]
113064769  ras-related protein M-Ras-like [KO:K07831]
113053213  ras-related protein M-Ras-like [KO:K07831]
113049467  ras-related protein R-Ras2 [KO:K07830]
113045725  ras-related protein R-Ras-like [KO:K07830]
113052020  ras-related protein R-Ras2 [KO:K07830]
113047256  ras-related protein R-Ras-like [KO:K07830]
113054940  raf1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
113068641  RAF proto-oncogene serine/threonine-protein kinase-like isoform X1 [KO:K04366] [EC:2.7.11.1]
113093139  transcription factor p65-like [KO:K04735]
113080235  transcription factor p65-like isoform X1 [KO:K04735]
113083585  transcription factor p65-like [KO:K04735]
113105396  transcription factor p65-like [KO:K04735]
113115191  transcription factor RelB-like isoform X1 [KO:K09253]
113058334  transcription factor RelB homolog isoform X1 [KO:K09253]
113115444  interleukin-12 subunit alpha-like [KO:K05406]
113046466  uncharacterized protein LOC113046466 [KO:K05406]
113114494  il12b; interleukin-12 subunit beta [KO:K05425]
113057745  interleukin-12 subunit beta-like [KO:K05425]
113057981  interleukin-12 subunit beta-like isoform X1 [KO:K05425]
113054665  interleukin-1 beta-like [KO:K04519]
113054687  interleukin-1 beta-like [KO:K04519]
113110504  interleukin-1 beta-like [KO:K04519]
113110505  interleukin-1 beta-like [KO:K04519]
113110506  interleukin-1 beta-like isoform X1 [KO:K04519]
113110507  interleukin-1 beta-like [KO:K04519]
113053997  tyrosine-protein kinase SYK-like isoform X1 [KO:K05855] [EC:2.7.10.2]
113109547  tyrosine-protein kinase SYK-like isoform X1 [KO:K05855] [EC:2.7.10.2]
113076374  tyrosine-protein phosphatase non-receptor type 11-like [KO:K07293] [EC:3.1.3.48]
113068902  tyrosine-protein phosphatase non-receptor type 11-like isoform X1 [KO:K07293] [EC:3.1.3.48]
113110180  tyrosine-protein phosphatase non-receptor type 11-like [KO:K07293] [EC:3.1.3.48]
113045589  tyrosine-protein phosphatase non-receptor type 11-like isoform X1 [KO:K07293] [EC:3.1.3.48]
113099908  tyrosine-protein phosphatase non-receptor type 11 [KO:K07293] [EC:3.1.3.48]
113101280  tyrosine-protein phosphatase non-receptor type 11 [KO:K07293] [EC:3.1.3.48]
113092744  STE20-like serine/threonine-protein kinase [KO:K04466] [EC:2.7.11.25]
113097181  mitogen-activated protein kinase kinase kinase 14-like isoform X1 [KO:K04466] [EC:2.7.11.25]
113047004  mitogen-activated protein kinase kinase kinase 14-like isoform X1 [KO:K04466] [EC:2.7.11.25]
113112701  inhibitor of nuclear factor kappa-B kinase subunit alpha [KO:K04467] [EC:2.7.11.10]
113056969  inhibitor of nuclear factor kappa-B kinase subunit alpha-like [KO:K04467] [EC:2.7.11.10]
113112768  nuclear factor NF-kappa-B p100 subunit-like [KO:K04469]
113057315  nuclear factor NF-kappa-B p100 subunit-like isoform X1 [KO:K04469]
113061559  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2-like [KO:K05859] [EC:3.1.4.11]
113061561  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2-like [KO:K05859] [EC:3.1.4.11]
113118238  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2-like [KO:K05859] [EC:3.1.4.11]
113055353  inositol 1,4,5-trisphosphate receptor type 1 isoform X1 [KO:K04958]
113094567  inositol 1,4,5-trisphosphate receptor type 1-like isoform X1 [KO:K04958]
113050374  inositol 1,4,5-trisphosphate receptor type 1-like isoform X1 [KO:K04958]
113110915  inositol 1,4,5-trisphosphate receptor type 1-like isoform X1 [KO:K04958]
113061517  inositol 1,4,5-trisphosphate receptor type 2-like [KO:K04959]
113118284  itpr2; inositol 1,4,5-trisphosphate receptor type 2 [KO:K04959]
113107211  inositol 1,4,5-trisphosphate receptor type 3-like isoform X1 [KO:K04960]
113069945  inositol 1,4,5-trisphosphate receptor type 3-like isoform X1 [KO:K04960]
113113030  calm2; calmodulin-2 [KO:K02183]
113078014  calmodulin [KO:K02183]
113043014  calmodulin-like protein 4 [KO:K02183]
113056129  calmodulin [KO:K02183]
113095065  calmodulin [KO:K02183]
113121099  calmodulin [KO:K02183]
113095975  calmodulin [KO:K02183]
113121164  calmodulin [KO:K02183]
113115290  calmodulin [KO:K02183]
113057229  calmodulin [KO:K02183]
113063032  calmodulin [KO:K02183]
113038517  calmodulin [KO:K02183]
113064143  calmodulin [KO:K02183]
113058580  calmodulin [KO:K02183]
113052481  calmodulin-like protein 4 [KO:K02183]
113117528  calmodulin [KO:K02183]
113111825  calmodulin [KO:K02183]
113106027  calmodulin-like protein 4 [KO:K02183]
113054264  serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform-like isoform X1 [KO:K04348] [EC:3.1.3.16]
113076543  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform-like isoform X1 [KO:K04348] [EC:3.1.3.16]
113113737  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform-like isoform X1 [KO:K04348] [EC:3.1.3.16]
113049916  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform-like isoform X1 [KO:K04348] [EC:3.1.3.16]
113069972  serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform-like isoform X1 [KO:K04348] [EC:3.1.3.16]
113109787  serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform-like isoform X1 [KO:K04348] [EC:3.1.3.16]
113057688  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform-like isoform X1 [KO:K04348] [EC:3.1.3.16]
113038475  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform-like isoform X1 [KO:K04348] [EC:3.1.3.16]
113064066  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform-like isoform X1 [KO:K04348] [EC:3.1.3.16]
113113102  calcineurin subunit B type 1-like [KO:K06268]
113048743  calcineurin subunit B type 1-like [KO:K06268]
113043992  calcineurin subunit B type 1 [KO:K06268]
113044093  calcineurin subunit B type 1 [KO:K06268]
113057414  calcineurin subunit B type 1-like [KO:K06268]
113120110  nuclear factor of activated T-cells, cytoplasmic 1-like isoform X1 [KO:K04446]
113057428  nuclear factor of activated T-cells, cytoplasmic 1-like isoform X1 [KO:K04446]
113041273  nuclear factor of activated T-cells, cytoplasmic 2-like isoform X1 [KO:K17332]
113050155  nuclear factor of activated T-cells, cytoplasmic 2-like isoform X1 [KO:K17332]
113104667  nuclear factor of activated T-cells, cytoplasmic 2-like [KO:K17332]
113065408  nuclear factor of activated T-cells, cytoplasmic 2-like isoform X1 [KO:K17332]
113065879  nuclear factor of activated T-cells, cytoplasmic 2-like isoform X1 [KO:K17332]
113067263  nuclear factor of activated T-cells, cytoplasmic 3-like isoform X1 [KO:K17333]
113043635  nuclear factor of activated T-cells, cytoplasmic 3-like [KO:K17333]
113051488  nuclear factor of activated T-cells, cytoplasmic 3-like isoform X1 [KO:K17333]
113106033  nuclear factor of activated T-cells, cytoplasmic 3-like isoform X1 [KO:K17333]
113119644  nuclear factor of activated T-cells, cytoplasmic 4-like [KO:K17334]
113045016  nfatc4; nuclear factor of activated T-cells, cytoplasmic 4 [KO:K17334]
113055241  interleukin-10-like [KO:K05443]
113111236  interleukin-10-like [KO:K05443]
113060562  early growth response protein 2b-like [KO:K12496]
113056331  early growth response protein 2b isoform X1 [KO:K12496]
113117098  early growth response protein 2b-like [KO:K12496]
113111926  early growth response protein 2b-like isoform X1 [KO:K12496]
113107444  egr3; early growth response protein 3 [KO:K12497]
113039683  early growth response protein 3-like [KO:K12497]
113120750  prostaglandin G/H synthase 2-like isoform X1 [KO:K11987] [EC:1.14.99.1]
113062963  prostaglandin G/H synthase 2-like [KO:K11987] [EC:1.14.99.1]
113115972  prostaglandin G/H synthase 2-like [KO:K11987] [EC:1.14.99.1]
113045805  prostaglandin G/H synthase 2-like [KO:K11987] [EC:1.14.99.1]
113072624  prostaglandin G/H synthase 2-like [KO:K11987] [EC:1.14.99.1]
113055278  protein kinase C delta type-like [KO:K06068] [EC:2.7.11.13]
113094825  protein kinase C delta type-like [KO:K06068] [EC:2.7.11.13]
113050390  protein kinase C delta type-like [KO:K06068] [EC:2.7.11.13]
113110979  protein kinase C delta type-like [KO:K06068] [EC:2.7.11.13]
113047409  mitogen-activated protein kinase 1-like [KO:K04371] [EC:2.7.11.24]
113068089  mitogen-activated protein kinase 1-like [KO:K04371] [EC:2.7.11.24]
113072016  mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
113046952  mitogen-activated protein kinase 1-like [KO:K04371] [EC:2.7.11.24]
113115898  apoptosis-associated speck-like protein containing a CARD isoform X1 [KO:K12799]
113110513  apoptosis-associated speck-like protein containing a CARD [KO:K12799]
113110529  apoptosis-associated speck-like protein containing a CARD [KO:K12799]
113045413  apoptosis-associated speck-like protein containing a CARD [KO:K12799]
113051882  apoptosis-associated speck-like protein containing a CARD [KO:K12799]
113115174  caspase-1-B-like [KO:K01370] [EC:3.4.22.36]
113115897  caspase-1-like [KO:K01370] [EC:3.4.22.36]
113082415  caspase-1-A-like [KO:K01370] [EC:3.4.22.36]
113052249  caspase-1-B-like isoform X1 [KO:K01370] [EC:3.4.22.36]
113059546  caspase-1-like [KO:K01370] [EC:3.4.22.36]
113105593  caspase-1-like isoform X1 [KO:K01370] [EC:3.4.22.36]
113074243  caspase-1-A-like [KO:K01370] [EC:3.4.22.36]
113049615  card9; caspase recruitment domain-containing protein 9 [KO:K12794]
113080339  caspase recruitment domain-containing protein 9-like [KO:K12794]
113046135  B-cell lymphoma/leukemia 10-like isoform X1 [KO:K07368]
113039793  B-cell lymphoma/leukemia 10-like isoform X1 [KO:K07368]
113061630  mucosa-associated lymphoid tissue lymphoma translocation protein 1-like isoform X1 [KO:K07369] [EC:3.4.22.-]
113049652  mucosa-associated lymphoid tissue lymphoma translocation protein 1-like isoform X1 [KO:K07369] [EC:3.4.22.-]
113080804  mucosa-associated lymphoid tissue lymphoma translocation protein 1-like isoform X1 [KO:K07369] [EC:3.4.22.-]
113064831  mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog [KO:K07369] [EC:3.4.22.-]
113040146  mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog isoform X1 [KO:K07369] [EC:3.4.22.-]
113091634  mucosa-associated lymphoid tissue lymphoma translocation protein 1-like [KO:K07369] [EC:3.4.22.-]
113093418  caspase-8-like [KO:K04398] [EC:3.4.22.61]
113093474  caspase-8-like isoform X1 [KO:K04398] [EC:3.4.22.61]
113048839  caspase-7-like [KO:K04398] [EC:3.4.22.61]
113108941  caspase-8-like [KO:K04398] [EC:3.4.22.61]
113050791  caspase-8-like [KO:K04398] [EC:3.4.22.61]
113050793  caspase-8-like [KO:K04398] [EC:3.4.22.61]
113094667  NF-kappa-B essential modulator-like isoform X1 [KO:K07210]
113069111  NF-kappa-B essential modulator-like [KO:K07210]
113106968  inhibitor of nuclear factor kappa-B kinase subunit beta-like [KO:K07209] [EC:2.7.11.10]
113052773  inhibitor of nuclear factor kappa-B kinase subunit beta-like isoform X1 [KO:K07209] [EC:2.7.11.10]
113060787  NF-kappa-B inhibitor alpha-like [KO:K04734]
113121096  NF-kappa-B inhibitor alpha-like [KO:K04734]
113121166  NF-kappa-B inhibitor alpha-like [KO:K04734]
113063031  NF-kappa-B inhibitor alpha-like [KO:K04734]
113117624  NF-kappa-B inhibitor alpha-like [KO:K04734]
113113844  nuclear factor NF-kappa-B p105 subunit-like isoform X1 [KO:K02580]
113057632  nuclear factor NF-kappa-B p105 subunit-like isoform X1 [KO:K02580]
113120270  tumor necrosis factor-like [KO:K03156]
113090802  tumor necrosis factor-like [KO:K03156]
113119662  interleukin-6-like [KO:K05405]
113119663  interleukin-6-like [KO:K05405]
113062448  uncharacterized protein LOC113062448 [KO:K05405]
113069455  uncharacterized protein LOC113069455 isoform X1 [KO:K05405]
113041113  mitogen-activated protein kinase 14A-like [KO:K04441] [EC:2.7.11.24]
113047963  mitogen-activated protein kinase 12-like [KO:K04441] [EC:2.7.11.24]
113047964  mitogen-activated protein kinase 11-like isoform X1 [KO:K04441] [EC:2.7.11.24]
113092486  mitogen-activated protein kinase 14A-like [KO:K04441] [EC:2.7.11.24]
113106988  mitogen-activated protein kinase 13-like [KO:K04441] [EC:2.7.11.24]
113048526  mitogen-activated protein kinase 12-like [KO:K04441] [EC:2.7.11.24]
113048528  mitogen-activated protein kinase 11-like isoform X1 [KO:K04441] [EC:2.7.11.24]
113076476  mitogen-activated protein kinase 14A isoform X1 [KO:K04441] [EC:2.7.11.24]
113093289  mitogen-activated protein kinase 12-like [KO:K04441] [EC:2.7.11.24]
113055097  mitogen-activated protein kinase 14B-like isoform X1 [KO:K04441] [EC:2.7.11.24]
113107629  mitogen-activated protein kinase 14A-like isoform X1 [KO:K04441] [EC:2.7.11.24]
113069393  mitogen-activated protein kinase 14B isoform X1 [KO:K04441] [EC:2.7.11.24]
113058295  mitogen-activated protein kinase 11-like [KO:K04441] [EC:2.7.11.24]
113064191  mitogen-activated protein kinase 11-like isoform X1 [KO:K04441] [EC:2.7.11.24]
113100762  mitogen-activated protein kinase 14A-like isoform X1 [KO:K04441] [EC:2.7.11.24]
113074136  mitogen-activated protein kinase 13-like [KO:K04441] [EC:2.7.11.24]
113118260  mitogen-activated protein kinase 12 [KO:K04441] [EC:2.7.11.24]
113112557  mitogen-activated protein kinase 8B isoform X1 [KO:K04440] [EC:2.7.11.24]
113056448  mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
113056870  mitogen-activated protein kinase 8B isoform X1 [KO:K04440] [EC:2.7.11.24]
113064006  mitogen-activated protein kinase 9-like isoform X1 [KO:K04440] [EC:2.7.11.24]
113038415  mitogen-activated protein kinase 9-like isoform X1 [KO:K04440] [EC:2.7.11.24]
113038881  mitogen-activated protein kinase 10-like isoform X1 [KO:K04440] [EC:2.7.11.24]
113064388  mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
113112062  mitogen-activated protein kinase 8-like isoform X1 [KO:K04440] [EC:2.7.11.24]
113121148  transcription factor AP-1-like [KO:K04448]
113063047  transcription factor AP-1-like [KO:K04448]
113069861  transcription factor AP-1-like [KO:K04448]
113070627  transcription factor AP-1-like [KO:K04448]
113054363  cblb; E3 ubiquitin-protein ligase CBL-B isoform X1 [KO:K22517] [EC:2.3.2.27]
113109881  E3 ubiquitin-protein ligase CBL-B-like [KO:K22517] [EC:2.3.2.27]
113069057  high affinity immunoglobulin epsilon receptor subunit gamma-like [KO:K07983]
113052264  high affinity immunoglobulin epsilon receptor subunit gamma-like [KO:K07983]
113046244  high affinity immunoglobulin epsilon receptor subunit gamma-like [KO:K07983]
113111429  high affinity immunoglobulin epsilon receptor subunit gamma-like [KO:K07983]
113105530  high affinity immunoglobulin epsilon receptor subunit gamma-like [KO:K07983]
113112322  high affinity immunoglobulin epsilon receptor subunit gamma-like [KO:K07983]
113061978  CD209 antigen-like protein E [KO:K06563]
113095373  CD209 antigen-like protein C [KO:K06563]
113049780  rho guanine nucleotide exchange factor 12-like isoform X1 [KO:K07532]
113115085  rho guanine nucleotide exchange factor 12-like isoform X1 [KO:K07532]
113081670  rho guanine nucleotide exchange factor 12-like isoform X1 [KO:K07532]
113058433  rho guanine nucleotide exchange factor 12-like isoform X1 [KO:K07532]
113050288  rho-related GTP-binding protein RhoA-D-like [KO:K04513]
113107545  rho-related GTP-binding protein RhoA-D-like [KO:K04513]
113040931  rho-related GTP-binding protein RhoA-C [KO:K04513]
113076614  transforming protein RhoA-like [KO:K04513]
113093569  rho-related GTP-binding protein RhoA-A isoform X1 [KO:K04513]
113107137  rho-related GTP-binding protein RhoA-A-like [KO:K04513]
113107264  rho-related GTP-binding protein RhoA-B isoform X1 [KO:K04513]
113093934  rho-related GTP-binding protein RhoA-B-like [KO:K04513]
113094044  rho-related GTP-binding protein RhoA-C-like [KO:K04513]
113107577  rho-related GTP-binding protein RhoA-B isoform X1 [KO:K04513]
113097730  transforming protein RhoA-like [KO:K04513]
113083306  transforming protein RhoA-like [KO:K04513]
113072081  rho-related GTP-binding protein RhoA-D [KO:K04513]
113105125  rho-related GTP-binding protein RhoA-D-like [KO:K04513]
113061434  serine/threonine-protein kinase PAK 1-like [KO:K04409] [EC:2.7.11.1]
113076743  serine/threonine-protein kinase PAK 1-like [KO:K04409] [EC:2.7.11.1]
113118104  serine/threonine-protein kinase PAK 1-like [KO:K04409] [EC:2.7.11.1]
113054487  kinase suppressor of Ras 1-like [KO:K14958]
113114814  kinase suppressor of Ras 1-like isoform X1 [KO:K14958]
113109995  kinase suppressor of Ras 1-like isoform X1 [KO:K14958]
113058681  kinase suppressor of Ras 1-like isoform X1 [KO:K14958]
113119136  serine/threonine-protein kinase PLK3-like [KO:K08862] [EC:2.7.11.21]
113037796  serine/threonine-protein kinase PLK3-like [KO:K08862] [EC:2.7.11.21]
113045432  serine/threonine-protein kinase PLK3-like [KO:K08862] [EC:2.7.11.21]
113041276  proto-oncogene tyrosine-protein kinase Src-like isoform X1 [KO:K05704] [EC:2.7.10.2]
113065632  proto-oncogene tyrosine-protein kinase Src isoform X1 [KO:K05704] [EC:2.7.10.2]
113111232  ikbke; inhibitor of nuclear factor kappa-B kinase subunit epsilon [KO:K07211] [EC:2.7.11.10]
113040769  signal transducer and activator of transcription 1-alpha/beta-like [KO:K11220]
113108355  signal transducer and activator of transcription 1-alpha/beta-like isoform X1 [KO:K11220]
113108356  signal transducer and activator of transcription 1-like [KO:K11220]
113064788  signal transducer and activator of transcription 1-alpha/beta-like [KO:K11220]
113039565  signal transducer and activator of transcription 1-alpha/beta-like isoform X1 [KO:K11220]
113053015  signal transducer and activator of transcription 1-like [KO:K11220]
113072465  interferon regulatory factor 8-like [KO:K04693]
113112118  interferon regulatory factor 8-like [KO:K04693]
113094065  signal transducer and activator of transcription 1-alpha/beta-like isoform X1 [KO:K11221]
113050351  signal transducer and activator of transcription 1-alpha/beta-like isoform X1 [KO:K11221]
113108806  interleukin-17D-like [KO:K05492]
113071895  interleukin-17D-like [KO:K05492]
113053395  interleukin-17D-like [KO:K05492]
113075634  ubiquitin carboxyl-terminal hydrolase CYLD-like isoform X1 [KO:K08601] [EC:3.4.19.12]
113095931  ubiquitin carboxyl-terminal hydrolase CYLD-like [KO:K08601] [EC:3.4.19.12]
113096277  ubiquitin carboxyl-terminal hydrolase CYLD-like isoform X1 [KO:K08601] [EC:3.4.19.12]
113050522  ubiquitin carboxyl-terminal hydrolase CYLD-like isoform X1 [KO:K08601] [EC:3.4.19.12]
113051416  ubiquitin carboxyl-terminal hydrolase CYLD-like isoform X1 [KO:K08601] [EC:3.4.19.12]
113100470  ubiquitin carboxyl-terminal hydrolase CYLD-like [KO:K08601] [EC:3.4.19.12]
113111164  ubiquitin carboxyl-terminal hydrolase CYLD-like [KO:K08601] [EC:3.4.19.12]
113106058  ubiquitin carboxyl-terminal hydrolase CYLD-like isoform X1 [KO:K08601] [EC:3.4.19.12]
113116668  B-cell lymphoma 3 protein homolog isoform X1 [KO:K09258]
113059073  B-cell lymphoma 3 protein homolog isoform X1 [KO:K09258]
113043503  C-C motif chemokine 22-like [KO:K21095]
113079030  C-C motif chemokine 22-like [KO:K21095]
113055239  MAP kinase-activated protein kinase 2-like [KO:K04443] [EC:2.7.11.1]
113107370  MAP kinase-activated protein kinase 2-like [KO:K04443] [EC:2.7.11.1]
113111235  MAP kinase-activated protein kinase 2 [KO:K04443] [EC:2.7.11.1]
113060009  CD209 antigen-like protein E [KO:K10059]
113093780  C-type lectin domain family 4 member E-like [KO:K10059]
113093788  C-type lectin domain family 7 member A-like [KO:K10059]
113107478  C-type lectin domain family 4 member E-like [KO:K10059]
113077896  CD209 antigen-like protein C [KO:K10059]
113061930  CD209 antigen-like protein E [KO:K10059]
113061931  C-type lectin domain family 6 member A-like [KO:K10059]
113062393  C-type lectin domain family 4 member F-like [KO:K10059]
113062579  C-type lectin domain family 4 member F-like [KO:K10059]
113116437  CD209 antigen-like protein E [KO:K10059]
113041468  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform-like [KO:K00922] [EC:2.7.1.153]
113041653  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like [KO:K00922] [EC:2.7.1.153]
113055327  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like [KO:K00922] [EC:2.7.1.153]
113115353  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
113110936  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
113065541  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform-like [KO:K00922] [EC:2.7.1.153]
113065620  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform-like [KO:K00922] [EC:2.7.1.153]
113049849  phosphatidylinositol 3-kinase regulatory subunit alpha-like isoform X1 [KO:K02649]
113050519  phosphatidylinositol 3-kinase regulatory subunit gamma-like isoform X1 [KO:K02649]
113116354  phosphatidylinositol 3-kinase regulatory subunit gamma-like [KO:K02649]
113083631  phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
113100537  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649]
113045905  phosphatidylinositol 3-kinase regulatory subunit gamma-like [KO:K02649]
113046111  phosphatidylinositol 3-kinase regulatory subunit gamma-like isoform X1 [KO:K02649]
113039997  phosphatidylinositol 3-kinase regulatory subunit gamma-like [KO:K02649]
113112806  RAC-gamma serine/threonine-protein kinase-like [KO:K04456] [EC:2.7.11.1]
113076709  RAC-gamma serine/threonine-protein kinase-like [KO:K04456] [EC:2.7.11.1]
113061850  RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
113121267  RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
113057112  RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
113110086  RAC-beta serine/threonine-protein kinase-like isoform X1 [KO:K04456] [EC:2.7.11.1]
113110125  RAC-beta serine/threonine-protein kinase-like isoform X1 [KO:K04456] [EC:2.7.11.1]
113117798  RAC-alpha serine/threonine-protein kinase-like [KO:K04456] [EC:2.7.11.1]
113117811  RAC-alpha serine/threonine-protein kinase-like [KO:K04456] [EC:2.7.11.1]
113059652  RAC-gamma serine/threonine-protein kinase-like [KO:K04456] [EC:2.7.11.1]
113118592  RAC-beta serine/threonine-protein kinase-like [KO:K04456] [EC:2.7.11.1]
113048224  E3 ubiquitin-protein ligase Mdm2-like isoform X1 [KO:K06643] [EC:2.3.2.27]
113061966  E3 ubiquitin-protein ligase Mdm2-like [KO:K06643] [EC:2.3.2.27]
113038191  interferon regulatory factor 1-like [KO:K09444]
113063787  interferon regulatory factor 1-like isoform X1 [KO:K09444]
Compound
C00027  Hydrogen peroxide
C00076  Calcium cation
C00159  D-Mannose
C00165  Diacylglycerol
C00584  Prostaglandin E2
C00965  1,3-beta-D-Glucan
C01019  L-Fucose
C01245  D-myo-Inositol 1,4,5-trisphosphate
C16844  Hydroxyl radical
C21790  Mycobacterial trehalose dimycolate
C21791  Rhodocytin
G13115  Mannose-capped lipoarabinomannan
Reference
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  Title
C-type lectin receptors in the control of T helper cell differentiation.
  Journal
Nat Rev Immunol 16:433-48 (2016)
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Front Immunol 5:288 (2014)
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Front Immunol 9:123 (2018)
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  Title
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C-type lectin-like receptors of the dectin-1 cluster: ligands and signaling pathways.
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A new path to IL-1beta production controlled by caspase-8.
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Nat Immunol 13:211-2 (2012)
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Reference
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Biomol Ther (Seoul) 20:433-45 (2012)
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Calcineurin-NFAT signalling in myeloid leucocytes: new prospects and pitfalls in immunosuppressive therapy.
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  Title
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Reference
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Reference
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Fucose-specific DC-SIGN signalling directs T helper cell type-2 responses via IKKepsilon- and CYLD-dependent Bcl3 activation.
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KO pathway
ko04625   
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