KEGG   PATHWAY: ppad04144
Entry
ppad04144                   Pathway                                
Name
Endocytosis - Panthera pardus (leopard)
Description
Endocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins entering through clathrin-dependent endocytosis (CDE) have sequences in their cytoplasmic domains that bind to the APs (adaptor-related protein complexes) and enable their rapid removal from the PM. In addition to APs and clathrin, there are numerous accessory proteins including dynamin. Depending on the various proteins that enter the endosome membrane, these cargoes are sorted to distinct destinations. Some cargoes, such as nutrient receptors, are recycled back to the PM. Ubiquitylated membrane proteins, such as activated growth-factor receptors, are sorted into intraluminal vesicles and eventually end up in the lysosome lumen via multivesicular endosomes (MVEs). There are distinct mechanisms of clathrin-independent endocytosis (CIE) depending upon the cargo and the cell type.
Class
Cellular Processes; Transport and catabolism
Pathway map
ppad04144  Endocytosis
ppad04144

Other DBs
GO: 0006897
Organism
Panthera pardus (leopard) [GN:ppad]
Gene
109245110  ARFGAP2; ADP-ribosylation factor GTPase-activating protein 2 isoform X1 [KO:K12493]
109245394  IGF2R; cation-independent mannose-6-phosphate receptor [KO:K06564]
109245518  CHMP1A; charged multivesicular body protein 1a [KO:K12197]
109245790  EPN2; epsin-2 isoform X1 [KO:K12471]
109245964  ACAP1; arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X1 [KO:K12489]
109246096  ARRB2; beta-arrestin-2 [KO:K04439]
109246097  PLD2; phospholipase D2 [KO:K01115] [EC:3.1.4.4]
109246100  RABEP1; rab GTPase-binding effector protein 1 [KO:K12480]
109246216  SH3GLB1; endophilin-B1 isoform X1 [KO:K11248]
109246510  ARAP2; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 isoform X1 [KO:K18440]
109246531  VPS37C; vacuolar protein sorting-associated protein 37C [KO:K12185]
109246759  SNX32; sorting nexin-32 isoform X1 [KO:K17920]
109246777  [KO:K23612]
109246837  GRK2; beta-adrenergic receptor kinase 1 [KO:K00910] [EC:2.7.11.15]
109246984  EHD1; EH domain-containing protein 1 [KO:K12483]
109247072  SH3GL2; endophilin-A1 [KO:K11247]
109247283  EPN3; epsin-3 isoform X1 [KO:K12471]
109247337  SNF8; vacuolar-sorting protein SNF8 isoform X1 [KO:K12188]
109247446  WIPF2; WAS/WASL-interacting protein family member 2 isoform X1 [KO:K19475]
109247530  RAB8A; ras-related protein Rab-8A [KO:K07901]
109247539  EPS15L1; epidermal growth factor receptor substrate 15-like 1 isoform X1 [KO:K12472]
109247572  MVB12A; multivesicular body subunit 12A isoform X1 [KO:K12186]
109247710  [KO:K04180]
109247805  RHOA; transforming protein RhoA [KO:K04513]
109248208  SMAP1; stromal membrane-associated protein 1 isoform X1 [KO:K12486]
109248388  CAPZA2; F-actin-capping protein subunit alpha-2 [KO:K10364]
109248391  CAV1; caveolin-1 isoform X1 [KO:K06278]
109248392  CAV2; caveolin-2 isoform X1 [KO:K12958]
109248641  RAB31; ras-related protein Rab-31 [KO:K07891]
109248713  PDCD6IP; programmed cell death 6-interacting protein isoform X1 [KO:K12200]
109248961  RAB4A; ras-related protein Rab-4A isoform X1 [KO:K07879]
109249052  ARF3; ADP-ribosylation factor 3 [KO:K07938]
109249533  [KO:K06751]
109249536  [KO:K06751]
109250052  SH3GLB2; endophilin-B2 isoform X1 [KO:K21269]
109250082  DNM1; dynamin-1 isoform X1 [KO:K01528] [EC:3.6.5.5]
109250105  PIP5KL1; phosphatidylinositol 4-phosphate 5-kinase-like protein 1 [KO:K13712] [EC:2.7.1.68]
109250158  MVB12B; multivesicular body subunit 12B isoform X1 [KO:K12186]
109250175  ARPC5L; actin-related protein 2/3 complex subunit 5-like protein [KO:K05754]
109250407  VPS26B; vacuolar protein sorting-associated protein 26B [KO:K18466]
109251195  CYTH3; cytohesin-3 isoform X1 [KO:K18441]
109251227  SMURF1; E3 ubiquitin-protein ligase SMURF1 isoform X1 [KO:K04678] [EC:2.3.2.26]
109251231  ARPC1A; actin-related protein 2/3 complex subunit 1A [KO:K05757]
109251233  ARPC1B; actin-related protein 2/3 complex subunit 1B [KO:K05757]
109251365  TGFBR2; TGF-beta receptor type-2 [KO:K04388] [EC:2.7.11.30]
109251732  PARD6G; partitioning defective 6 homolog gamma [KO:K06093]
109251891  RAB11FIP4; rab11 family-interacting protein 4 isoform X1 [KO:K12485]
109251948  AP2B1; AP-2 complex subunit beta isoform X1 [KO:K11825]
109252042  CHMP5; charged multivesicular body protein 5 [KO:K12198]
109252158  PSD2; PH and SEC7 domain-containing protein 2 isoform X1 [KO:K12494]
109252207  ARAP3; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1 [KO:K12490]
109252380  AGAP3; arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform X1 [KO:K12491]
109252388  DNM3; dynamin-3 isoform X1 [KO:K01528] [EC:3.6.5.5]
109252409  ACTR3B; actin-related protein 3B isoform X1 [KO:K18584]
109252547  VTA1; vacuolar protein sorting-associated protein VTA1 homolog [KO:K12199]
109252878  [KO:K18441]
109253031  AP2A1; LOW QUALITY PROTEIN: AP-2 complex subunit alpha-1 [KO:K11824]
109253153  EHD2; EH domain-containing protein 2 [KO:K12469]
109253183  AP2S1; AP-2 complex subunit sigma [KO:K11827]
109253261  CBLC; E3 ubiquitin-protein ligase CBL-C isoform X1 [KO:K22518] [EC:2.3.2.27]
109253333  SNX6; sorting nexin-6 [KO:K17920]
109253414  ARFGAP1; ADP-ribosylation factor GTPase-activating protein 1 isoform X1 [KO:K12492]
109253418  [KO:K23612]
109253474  RAB22A; ras-related protein Rab-22A isoform X1 [KO:K07891]
109253514  GRK3; beta-adrenergic receptor kinase 2 isoform X1 [KO:K00910] [EC:2.7.11.15]
109253886  ARPC5; actin-related protein 2/3 complex subunit 5 [KO:K05754]
109254084  LDLR; low-density lipoprotein receptor [KO:K12473]
109254091  DNM2; dynamin-2 isoform X1 [KO:K23484]
109254219  RAB11B; ras-related protein Rab-11B [KO:K07905]
109254390  ARPC4; actin-related protein 2/3 complex subunit 4 [KO:K05755]
109254405  CAV3; caveolin-3 [KO:K12959]
109254607  SNX12; sorting nexin-12 [KO:K17918]
109254610  IL2RG; cytokine receptor common subunit gamma [KO:K05070]
109254860  SMAP2; stromal membrane-associated protein 2 [KO:K12486]
109254985  CHMP4A; charged multivesicular body protein 4a isoform X1 [KO:K12194]
109255204  GIT1; ARF GTPase-activating protein GIT1 isoform X1 [KO:K05737]
109255352  CHMP2B; charged multivesicular body protein 2b [KO:K12192]
109255916  PIP5K1C; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [KO:K00889] [EC:2.7.1.68]
109255947  SH3GL1; endophilin-A2 isoform X1 [KO:K11247]
109256019  [KO:K12495]
109256040  RAB7A; ras-related protein Rab-7a [KO:K07897]
109256112  CLTC; clathrin heavy chain 1 [KO:K04646]
109256385  SH3KBP1; SH3 domain-containing kinase-binding protein 1 isoform X1 [KO:K12470]
109256994  PIP5K1A; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1 [KO:K00889] [EC:2.7.1.68]
109257054  VPS45; vacuolar protein sorting-associated protein 45 isoform X1 [KO:K12479]
109257415  HSPA8; heat shock cognate 71 kDa protein [KO:K03283]
109257493  RBSN; rabenosyn-5 isoform X1 [KO:K12481]
109257626  CHMP1B; charged multivesicular body protein 1b [KO:K12197]
109257761  [KO:K03283]
109258392  VPS28; vacuolar protein sorting-associated protein 28 homolog isoform X1 [KO:K12184]
109258513  RAB5A; ras-related protein Rab-5A isoform X1 [KO:K07887]
109258524  RAB5C; ras-related protein Rab-5C [KO:K07889]
109258594  VPS25; vacuolar protein-sorting-associated protein 25 isoform X1 [KO:K12189]
109258633  CLTCL1; clathrin heavy chain 2 isoform X1 [KO:K04646]
109259593  ARF1; ADP-ribosylation factor 1 [KO:K07937]
109259617  RAB11FIP3; rab11 family-interacting protein 3 [KO:K12485]
109259749  [KO:K07937]
109259759  [KO:K02833]
109259784  AP2A2; AP-2 complex subunit alpha-2 isoform X1 [KO:K11824]
109259909  EPN1; epsin-1 isoform X1 [KO:K12471]
109260054  ACTR2; actin-related protein 2 isoform X1 [KO:K17260]
109260221  GRK7; rhodopsin kinase isoform X1 [KO:K00909] [EC:2.7.11.14]
109260278  IQSEC2; IQ motif and SEC7 domain-containing protein 2 isoform X1 [KO:K12495]
109260444  CHMP2A; charged multivesicular body protein 2a [KO:K12191]
109260541  [KO:K03283]
109260547  [KO:K06751]
109260550  HSPA1A; heat shock 70 kDa protein 1A isoform X1 [KO:K03283]
109260633  [KO:K06751]
109260801  [KO:K12495]
109261321  [KO:K06751]
109261353  [KO:K06751]
109261485  [KO:K06751]
109261493  [KO:K06751]
109261573  [KO:K06751]
109261804  [KO:K12471]
109261879  [KO:K03283]
109262118  PRKCI; protein kinase C iota type isoform X1 [KO:K06069] [EC:2.7.11.13]
109262235  PSD3; PH and SEC7 domain-containing protein 3 isoform X1 [KO:K12494]
109262318  RAB11FIP1; rab11 family-interacting protein 1 isoform X1 [KO:K12484]
109262710  PML; protein PML isoform X1 [KO:K10054] [EC:2.3.2.-]
109262802  SMAD3; mothers against decapentaplegic homolog 3 isoform X1 [KO:K23605]
109262826  RAB11A; ras-related protein Rab-11A [KO:K07904]
109262837  RAB11FIP5; rab11 family-interacting protein 5 isoform X1 [KO:K12484]
109262847  SPG21; maspardin isoform X1 [KO:K19367]
109262868  SNX1; sorting nexin-1 isoform X1 [KO:K17917]
109262934  STAMBP; STAM-binding protein isoform X1 [KO:K11866] [EC:3.4.19.12]
109262946  NEDD4; E3 ubiquitin-protein ligase NEDD4 isoform X1 [KO:K10591] [EC:2.3.2.26]
109262999  USP8; ubiquitin carboxyl-terminal hydrolase 8 [KO:K11839] [EC:3.4.19.12]
109263116  EHD4; EH domain-containing protein 4 [KO:K12477]
109263349  ASAP2; arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 [KO:K12488]
109263504  SNX3; sorting nexin-3 [KO:K17918]
109263605  WIPF3; WAS/WASL-interacting protein family member 3 [KO:K19475]
109264025  GRK1; rhodopsin kinase isoform X1 [KO:K00909] [EC:2.7.11.14]
109264329  RUFY2; RUN and FYVE domain-containing protein 2 isoform X1 [KO:K12482]
109264347  VPS26A; vacuolar protein sorting-associated protein 26A isoform X1 [KO:K18466]
109264425  PSD4; PH and SEC7 domain-containing protein 4 isoform X1 [KO:K12494]
109264573  [KO:K18462]
109264859  AGAP1; arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 isoform X1 [KO:K12491]
109265076  ARPC2; actin-related protein 2/3 complex subunit 2 [KO:K05758]
109265077  CXCR1; C-X-C chemokine receptor type 1 [KO:K04175]
109265081  CXCR2; C-X-C chemokine receptor type 2 [KO:K05050]
109265229  CYTH4; cytohesin-4 [KO:K18441]
109265321  EEA1; early endosome antigen 1 isoform X1 [KO:K12478]
109265413  WASHC3; WASH complex subunit CCDC53 isoform X1 [KO:K18463]
109265447  WASHC4; WASH complex subunit SWIP isoform X1 [KO:K18465]
109265527  IL2RB; interleukin-2 receptor subunit beta isoform X1 [KO:K05069]
109265671  ARFGAP3; ADP-ribosylation factor GTPase-activating protein 3 isoform X1 [KO:K12493]
109266002  VPS36; vacuolar protein-sorting-associated protein 36 isoform X1 [KO:K12190]
109266039  SPG20; spartin isoform X1 [KO:K19366]
109266237  TFRC; transferrin receptor protein 1 [KO:K06503]
109266320  EHD3; EH domain-containing protein 3 [KO:K12476]
109266341  CBLB; E3 ubiquitin-protein ligase CBL-B isoform X1 [KO:K22517] [EC:2.3.2.27]
109266520  SNX4; sorting nexin-4 isoform X1 [KO:K17919]
109266572  ACAP2; arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 isoform X1 [KO:K12489]
109266727  DNAJC6; putative tyrosine-protein phosphatase auxilin isoform X1 [KO:K09526]
109266878  ZFYVE9; zinc finger FYVE domain-containing protein 9 isoform X1 [KO:K04679]
109266890  EPS15; epidermal growth factor receptor substrate 15 isoform X1 [KO:K12472]
109267137  [KO:K13649]
109267139  [KO:K13649]
109267142  [KO:K13649]
109267149  ARAP1; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 isoform X1 [KO:K18439]
109267207  ARRB1; beta-arrestin-1 isoform X1 [KO:K04439]
109267300  RAB10; ras-related protein Rab-10 [KO:K07903]
109267551  CLTB; clathrin light chain B isoform X1 [KO:K04645]
109267570  FGFR4; fibroblast growth factor receptor 4 isoform X1 [KO:K05095] [EC:2.7.10.1]
109267583  GRK6; G protein-coupled receptor kinase 6 [KO:K08291] [EC:2.7.11.16]
109267979  EGFR; epidermal growth factor receptor isoform X1 [KO:K04361] [EC:2.7.10.1]
109268030  AMPH; amphiphysin isoform X1 [KO:K12562]
109268511  ARF6; ADP-ribosylation factor 6 [KO:K07941]
109268563  [KO:K23612]
109268680  CAPZA3; F-actin-capping protein subunit alpha-3 [KO:K10364]
109268919  WASL; neural Wiskott-Aldrich syndrome protein [KO:K23612]
109268935  ARF5; ADP-ribosylation factor 5 [KO:K07940]
109269307  ARFGEF1; brefeldin A-inhibited guanine nucleotide-exchange protein 1 isoform X1 [KO:K18442]
109269421  CHMP4C; charged multivesicular body protein 4c [KO:K24782]
109269443  WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X1 [KO:K05633] [EC:2.3.2.26]
109269752  GRK4; G protein-coupled receptor kinase 4 isoform X1 [KO:K08291] [EC:2.7.11.16]
109269781  FGFR3; fibroblast growth factor receptor 3 isoform X1 [KO:K05094] [EC:2.7.10.1]
109269943  ACTR3; actin-related protein 3 [KO:K18584]
109270084  TGFBR1; TGF-beta receptor type-1 isoform X1 [KO:K04674] [EC:2.7.11.30]
109270144  CLTA; clathrin light chain A isoform X1 [KO:K04644]
109270310  RAB5B; ras-related protein Rab-5B [KO:K07888]
109270324  RNF41; E3 ubiquitin-protein ligase NRDP1 [KO:K11981] [EC:2.3.2.27]
109270372  CXCR4; C-X-C chemokine receptor type 4 [KO:K04189]
109270378  KIF5A; kinesin heavy chain isoform X1 [KO:K10396] [EC:5.6.1.3]
109270388  AGAP2; arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 isoform X1 [KO:K17848]
109270482  MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1 [KO:K06643] [EC:2.3.2.27]
109270674  IST1; IST1 homolog isoform X1 [KO:K19476]
109270708  VPS4A; vacuolar protein sorting-associated protein 4A isoform X1 [KO:K12196]
109270759  PARD6A; partitioning defective 6 homolog alpha isoform X1 [KO:K06093]
109270811  KIF5C; kinesin heavy chain [KO:K10396] [EC:5.6.1.3]
109270988  VPS35; vacuolar protein sorting-associated protein 35 [KO:K18468]
109271174  STAM2; signal transducing adapter molecule 2 isoform X1 [KO:K04705]
109271221  TSG101; tumor susceptibility gene 101 protein isoform X1 [KO:K12183]
109272064  CAPZA1; F-actin-capping protein subunit alpha-1 isoform X1 [KO:K10364]
109272278  PARD6B; partitioning defective 6 homolog beta [KO:K06093]
109272308  ARFGEF2; brefeldin A-inhibited guanine nucleotide-exchange protein 2 isoform X1 [KO:K18442]
109272472  SRC; proto-oncogene tyrosine-protein kinase Src isoform X1 [KO:K05704] [EC:2.7.10.2]
109272538  ITCH; E3 ubiquitin-protein ligase Itchy homolog isoform X1 [KO:K05632] [EC:2.3.2.26]
109272546  CHMP4B; charged multivesicular body protein 4b [KO:K12194]
109272733  ZFYVE27; protrudin isoform X1 [KO:K19368]
109272815  GBF1; Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 [KO:K18443]
109272819  PSD; PH and SEC7 domain-containing protein 1 isoform X1 [KO:K12494]
109272963  RAB11FIP2; rab11 family-interacting protein 2 isoform X1 [KO:K12484]
109272977  GRK5; G protein-coupled receptor kinase 5 isoform X1 [KO:K08291] [EC:2.7.11.16]
109272992  FGFR2; fibroblast growth factor receptor 2 isoform X1 [KO:K05093] [EC:2.7.10.1]
109273120  ASAP1; arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X1 [KO:K12488]
109273156  WASHC5; WASH complex subunit strumpellin isoform X1 [KO:K18464]
109273253  WIPF1; WAS/WASL-interacting protein family member 1 isoform X1 [KO:K19475]
109273360  IGF1R; insulin-like growth factor 1 receptor [KO:K05087] [EC:2.7.10.1]
109273530  SH3GL3; endophilin-A3 isoform X1 [KO:K11247]
109273677  STAM; signal transducing adapter molecule 1 isoform X1 [KO:K04705]
109273771  IL2RA; interleukin-2 receptor subunit alpha isoform X1 [KO:K05068]
109273850  ACAP3; arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 [KO:K12489]
109273956  PRKCZ; protein kinase C zeta type isoform X1 [KO:K18952] [EC:2.7.11.13]
109274221  CAPZB; F-actin-capping protein subunit beta isoform X1 [KO:K10365]
109274276  CDC42; cell division control protein 42 homolog [KO:K04393]
109274296  ASAP3; LOW QUALITY PROTEIN: arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 [KO:K12488]
109274334  LDLRAP1; low density lipoprotein receptor adapter protein 1 isoform X1 [KO:K12474]
109274682  SNX5; sorting nexin-5 isoform X1 [KO:K17920]
109274924  ZFYVE16; zinc finger FYVE domain-containing protein 16 isoform X1 [KO:K04679]
109275130  PLD1; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
109275219  AP2M1; AP-2 complex subunit mu isoform X1 [KO:K11826]
109275437  PIP5K1B; phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1 [KO:K00889] [EC:2.7.1.68]
109275620  VPS4B; vacuolar protein sorting-associated protein 4B [KO:K12196]
109275670  NEDD4L; E3 ubiquitin-protein ligase NEDD4-like isoform X1 [KO:K13305] [EC:2.3.2.26]
109275745  SMAD2; mothers against decapentaplegic homolog 2 isoform X1 [KO:K04500]
109275837  DAB2; disabled homolog 2 isoform X1 [KO:K12475]
109276227  WASHC1; WAS protein family homolog 1 [KO:K18461]
109276228  IQSEC3; IQ motif and SEC7 domain-containing protein 3 isoform X1 [KO:K12495]
109276301  PARD3; partitioning defective 3 homolog isoform X1 [KO:K04237]
109276315  KIF5B; kinesin-1 heavy chain [KO:K10396] [EC:5.6.1.3]
109276777  HGS; hepatocyte growth factor-regulated tyrosine kinase substrate isoform X1 [KO:K12182]
109276799  CHMP6; charged multivesicular body protein 6 isoform X1 [KO:K12195]
109276844  CYTH1; cytohesin-1 isoform X1 [KO:K18441]
109277076  SMURF2; E3 ubiquitin-protein ligase SMURF2 isoform X1 [KO:K04678] [EC:2.3.2.26]
109277207  VPS37A; vacuolar protein sorting-associated protein 37A isoform X1 [KO:K12185]
109277333  CHMP7; charged multivesicular body protein 7 [KO:K15053]
109277460  GIT2; ARF GTPase-activating protein GIT2 isoform X1 [KO:K12487]
109277546  RAB35; ras-related protein Rab-35 isoform X1 [KO:K07876]
109277664  VPS29; vacuolar protein sorting-associated protein 29 isoform X1 [KO:K18467]
109277667  ARPC3; actin-related protein 2/3 complex subunit 3 isoform X1 [KO:K05756]
109277722  VPS37B; vacuolar protein sorting-associated protein 37B isoform X1 [KO:K12185]
109278523  CBL; E3 ubiquitin-protein ligase CBL [KO:K04707] [EC:2.3.2.27]
109278792  BIN1; myc box-dependent-interacting protein 1 isoform X1 [KO:K12562]
109278822  [KO:K10364]
109278874  SNX2; sorting nexin-2 isoform X1 [KO:K17917]
109278958  RUFY1; RUN and FYVE domain-containing protein 1 isoform X1 [KO:K12482]
109278988  PDGFRA; platelet-derived growth factor receptor alpha [KO:K04363] [EC:2.7.10.1]
109279099  ARF4; ADP-ribosylation factor 4 [KO:K07939]
109279193  TRAF6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
Compound
C00035  GDP
C00044  GTP
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
Reference
PMID:19007773
  Authors
Acconcia F, Sigismund S, Polo S
  Title
Ubiquitin in trafficking: the network at work.
  Journal
Exp Cell Res 315:1610-8 (2009)
DOI:10.1016/j.yexcr.2008.10.014
Reference
PMID:18647649
  Authors
Donaldson JG, Porat-Shliom N, Cohen LA
  Title
Clathrin-independent endocytosis: a unique platform for cell signaling and PM remodeling.
  Journal
Cell Signal 21:1-6 (2009)
DOI:10.1016/j.cellsig.2008.06.020
Reference
PMID:15261671
  Authors
Sorkin A
  Title
Cargo recognition during clathrin-mediated endocytosis: a team effort.
  Journal
Curr Opin Cell Biol 16:392-9 (2004)
DOI:10.1016/j.ceb.2004.06.001
Reference
PMID:19325624
  Authors
Raiborg C, Stenmark H
  Title
The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins.
  Journal
Nature 458:445-52 (2009)
DOI:10.1038/nature07961
Reference
PMID:20110990
  Authors
Scita G, Di Fiore PP
  Title
The endocytic matrix.
  Journal
Nature 463:464-73 (2010)
DOI:10.1038/nature08910
Reference
PMID:15687999
  Authors
Le Roy C, Wrana JL
  Title
Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling.
  Journal
Nat Rev Mol Cell Biol 6:112-26 (2005)
DOI:10.1038/nrm1571
Reference
PMID:19924646
  Authors
Jovic M, Sharma M, Rahajeng J, Caplan S
  Title
The early endosome: a busy sorting station for proteins at the crossroads.
  Journal
Histol Histopathol 25:99-112 (2010)
DOI:10.14670/HH-25.99
Reference
PMID:16203612
  Authors
Pietiainen VM, Marjomaki V, Heino J, Hyypia T
  Title
Viral entry, lipid rafts and caveosomes.
  Journal
Ann Med 37:394-403 (2005)
DOI:10.1080/07853890510011976
Reference
PMID:19696797
  Authors
Grant BD, Donaldson JG
  Title
Pathways and mechanisms of endocytic recycling.
  Journal
Nat Rev Mol Cell Biol 10:597-608 (2009)
DOI:10.1038/nrm2755
Reference
PMID:22193161
  Authors
Cullen PJ, Korswagen HC
  Title
Sorting nexins provide diversity for retromer-dependent trafficking events.
  Journal
Nat Cell Biol 14:29-37 (2012)
DOI:10.1038/ncb2374
Related
pathway
ppad04060  Cytokine-cytokine receptor interaction
ppad04070  Phosphatidylinositol signaling system
ppad04130  SNARE interactions in vesicular transport
ppad04142  Lysosome
ppad04350  TGF-beta signaling pathway
KO pathway
ko04144   

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