KEGG MEDICUS 疾患情報 |
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| エントリ | 名称 | 概要 | カテゴリ | パスウェイ | 病因遺伝子 |
|---|---|---|---|---|---|
| H01625 |
バージャー病 ビュルガー病 閉塞性血栓血管炎 |
Buerger disease, also known as thromboangiitis obliterans, is a nonatherosclerotic, inflammatory disease that most commonly affects the small and medium-sized arteries and veins in the upper and lower ... | 免疫系疾患 | ||
| H01626 | 閉塞性動脈硬化症 | Arteriosclerosis obliterans (ASO) is one of the most common peripheral vascular diseases that causes ischemic symptoms of the lower limbs. Symptoms include discomfort, numbness, intermittent claudication ... | 循環器系疾患 | ||
| H01628 | オピストルキス症 | Opisthorchiasis comprises diverse clinical symptoms caused by infections with Opisthorchis felineus or Opisthorchis viverrini liver flukes, which are transmitted by eating infected raw or undercooked fish ... | 寄生虫感染症 | ||
| H01629 | 慢性動脈閉塞症 | Chronic arterial occlusive disease is a highly prevalent peripheral vascular disorder. This disease is caused by arteriosclerosis obliterans (ASO), thromboangiitis obliterans (Buerger's disease), primary ... | 循環器系疾患 | ||
| H01630 | 動脈管開存症 | Patent ductus arteriosus (PDA) is a common congenital heart defect with both inherited and acquired causes. The ductus arteriosus (DA) is a fetal specific vascular connection between the main pulmonary ... | 先天奇形 |
(PDA2) TFAP2B [HSA:7021] [KO:K09176] (PDA3) PRDM6 [HSA:93166] [KO:K20795] |
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| H01631 | 急性心不全 | Acute heart failure (AHF) can be defined as a heterogeneous syndrome of signs and symptoms of new-onset or gradual/rapidly worsening heart failure (HF), requiring urgent therapy. Intrinsic cardiac abnormalities ... | 循環器系疾患 | PPA2 [HSA:27068] [KO:K01507] | |
| H01632 | 狭心症 | Angina pectoris is defined as cardiac-induced pain arising from a lack of myocardial oxygen. "Angina" is used to describe clinical symptoms such as discomfort in the chest, jaw, shoulder, back, or arms ... | 循環器系疾患 | ||
| H01633 | 高血圧症 | High blood pressure (hypertension) is the most frequent classic cardiovascular risk factor and accounts for a large proportion of cardiovascular mortality, the main cause of death worldwide. Hypertension ... | 循環器系疾患 |
(EHT) PTGIS [HSA:5740] [KO:K01831] (EHT) AGTR1 [HSA:185] [KO:K04166] (EHT) ADD1 [HSA:118] [KO:K18622] (EHT) AGT [HSA:183] [KO:K09821] (EHT) ECE1 [HSA:1889] [KO:K01415] (EHT) CYP3A5 [HSA:1577] [KO:K17690] (EHT) NOS3 [HSA:4846] [KO:K13242] (EHT) GNB3 [HSA:2784] [KO:K07825] NR3C2 [HSA:4306] [KO:K08555] (GRA) CYP11B2 [HSA:1585] [KO:K07433] (GRA) CYP11B1 [HSA:1584] [KO:K00497] (AME) HSD11B2 [HSA:3291] [KO:K00071] (LIDLS) SCNN1B [HSA:6338] [KO:K04825] (LIDLS) SCNN1G [HSA:6340] [KO:K04827] (LIDLS) SCNN1A [HSA:6337] [KO:K04824] |
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| H01634 | 消化性潰瘍 | Peptic ulcer is a common disorder of gastrointestinal system characterized by mucosal damage secondary to pepsin and gastric acid secretion. It usually occurs in the stomach and proximal duodenum. Typical ... | 消化器系疾患 | ||
| H01635 |
脂質異常症 高脂血症 |
Dyslipidemia is a condition characterized by either an increase or decrease in concentration of lipids in the blood. Hyperlipidemia, which refers to an increase in cholesterol, triglyceride (TG), or both ... | 内分泌代謝疾患 |
(Hyperlipoproteinemia type 1) APOC2 [HSA:344] [KO:K22287] (Hyperlipoproteinemia type 1,2) LPL [HSA:4023] [KO:K01059] (Hyperlipoproteinemia type 2) LDLR [HSA:3949] [KO:K12473] (Hyperlipoproteinemia type 5) APOA5 [HSA:116519] [KO:K09025] |
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| H01636 |
線維筋痛症 線維筋痛症候群 |
Fibromyalgia is a common and chronic pain disorder that predominantly affects women. It belongs to the group of rheumatic disorders of the soft tissues, and is characterised by widespread chronic pain ... | 筋骨格疾患 | ||
| H01637 | 高トリグリセリド血症 | Hypertriglyceridemia (HTG) is a condition with fasting triglyceride (TG) levels in blood continuing to rise. HTG generally refers to an increase of plasma triglyceride (TG) concentrations above the 95th ... | 内分泌代謝疾患 |
(HYTG1) APOA5 [HSA:116519] [KO:K09025] (HYTG2) CREB3L3 [HSA:84699] [KO:K09048] |
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| H01638 | 神経障害性疼痛 | Neuropathic pain is defined as pain caused by a lesion or disease affecting the somatosensory nervous system, and may be generated by either the peripheral or central nervous system, or both. It is especially ... | 神経系疾患 | ||
| H01639 | 子宮内膜症 | Endometriosis is defined as the growth of the endometrial glands and stroma at extra-uterine sites, which are most commonly implanted over and under visceral and peritoneal surfaces within the female pelvis ... | 生殖器系疾患 | ||
| H01640 | 子宮筋腫 | Uterine leiomyoma, also known as fibroid, is the most common benign neoplasm of the female genital tract. It is a discrete, round, firm, often multiple uterine tumor composed of smooth muscle and connective ... | 生殖器系疾患 |
HMGA2 (rearrangement) [HSA:8091] [KO:K09283] MED12 (mutation) [HSA:9968] [KO:K15162] COL4A6-COL4A5 (deletion) [HSA:1288 1287] [KO:K06237] Fumarate hydratase (FH) (inactivation) [HSA:2271] [KO:K01679] |
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| H01641 | ドライアイ | Dry eye disease (also called keratoconjunctivitis sicca) is multifactorial disease of the tears, lids, and ocular surface which can result in symptoms of discomfort and/or visual disturbance and/or tear ... | 神経系疾患 | ||
| H01642 | 腎性貧血 | Renal anemia is one of the most frequent complications of chronic kidney disease. Anemia leads to a decrease in oxygen delivery to vital organs, which is initially compensated for by tachycardia and cardiac ... | 泌尿器系疾患 | ||
| H01643 | 凍瘡 | Chilblains, or pernio, is a localized inflammatory lesion of the skin resulting from an abnormal response to cold. It is characterized by persistent purple or purple-red nodules on acral skin, most commonly ... | 免疫系疾患; 皮膚疾患 | ||
| H01644 | 眼瞼炎 | Blepharitis is a chronic inflammatory condition of the eyelids associated with itchiness, redness, flaking, and crusting. It is among the most common ocular conditions affecting both children and adults ... | 神経系疾患 | ||
| H01645 |
甲状腺機能亢進症 甲状腺中毒症 |
Hyperthyroidism is a pathological disorder characterised by increased thyroid hormone synthesis and secretion from the thyroid gland. The term thyrotoxicosis is not synonymous with hyperthyroidism. Thyrotoxicosis ... | 内分泌代謝疾患 | ||
| H01646 | うつ病 | Major depressive disorder (MDD) is the most common psychiatric disorder mainly characterized by depressed mood, loss of interest, feelings of worthlessness, and a high risk of suicide. Accumulated evidence ... | 精神及び行動の障害 |
TPH2 [HSA:121278] [KO:K00502] HTR2A [HSA:3356] [KO:K04157] FKBP5 [HSA:2289] [KO:K09571] |
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| H01647 | 亜急性甲状腺炎 | Subacute thyroiditis (SAT), also called subacute granulomatous or de Quervain thyroiditis, is a spontaneously remitting, painful, inflammatory disease of the thyroid gland, which is considered the most ... | 内分泌代謝疾患 | ||
| H01648 | 天疱瘡 | Pemphigus is an autoimmune blistering disease of the skin and mucous membranes characterized by circulating autoantibodies that target desmosomal components as well as other epithelial antigens and impair ... | 免疫系疾患; 皮膚疾患 | ||
| H01649 | 統合失調症 | Schizophrenia (SCZD) is a common serious psychotic illness that typically emerges in late adolescence and early adulthood. It is characterized by hallucinations and delusions (commonly known as positive ... | 精神及び行動の障害 |
(SCZD4) PRODH [HSA:5625] [KO:K00318] (SCZD6) NRG1 [HSA:3084] [KO:K05455] (SCZD9) DISC1 [HSA:27185] [KO:K16534] (SCZD15) SHANK3 [HSA:85358] [KO:K15009] (SZCD17) NRXN1 [HSA:9378] [KO:K07377] (SCZD18) SLC1A1 [HSA:6505] [KO:K05612] (SCZD19) RBM12 [HSA:10137] [KO:K24526] MTHFR [HSA:4524] [KO:K25004] CHI3L1 [HSA:1116] [KO:K17523] SYN2 [HSA:6854] [KO:K19941] DRD3 [HSA:1814] [KO:K04146] RTN4R [HSA:65078] [KO:K16659] DAOA [HSA:267012] [KO:K24397] HTR2A [HSA:3356] [KO:K04157] AKT1 [HSA:207] [KO:K04456] C4A [HSA:720] [KO:K03989] APOL2 [HSA:23780] [KO:K14480] APOL4 [HSA:80832] [KO:K14480] COMT [HSA:1312] [KO:K00545] |
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| H01650 | 類天疱瘡 | Pemphigoid diseases are group of autoimmune blistering disorders of the skin and mucous membranes characterized by autoantibodies directed against structural proteins of the dermal-epidermal junction that ... | 免疫系疾患; 皮膚疾患 | ||
| H01651 | 黄斑浮腫 | Macular edema is a common feature of many diseases of the retina, such as intraocular inflammation (uveitis), central or branch retinal vein occlusion, diabetic retinopathy and following cataract extraction ... | 神経系疾患 | ||
| H01652 | 脂漏性皮膚炎 | Seborrheic dermatitis (SD) is a common inflammatory dermatological disorder. The characteristic symptoms include scaling, erythema, and itching, which occur most often on the scalp, face, chest, back, ... | 免疫系疾患; 皮膚疾患 | ||
| H01653 |
双極性障害 躁うつ病 |
Bipolar disorder, previously known as manic depressive illness, is a severe chronic mood disorder, characterized by the recurrence of mania (hypomania), depression, or mixed episodes. It is one of the ... | 精神及び行動の障害 | (MAFD7) XBP1 [HSA:7494] [KO:K09027] | |
| H01654 | 扁平苔癬 | Lichen planus (LP) is a chronic inflammatory and immune mediated skin disease with characteristic clinical and histopathologic features. The skin and oral mucosa are the most frequently involved areas ... | 免疫系疾患; 皮膚疾患 | ||
| H01655 |
多発血管炎性肉芽腫症 ウェゲナー肉芽腫症 |
Granulomatosis with polyangitis (GPA) is an idiopathic, systemic inflammatory disease characterized by necrotizing granulomatous inflammation and pauci-immune small- vessel vasculitis of upper and lower ... | 免疫系疾患 |