KEGG ORTHOLOGY: K21954

ORTHOLOGY: K21954

Entry

K21954                      KO

Symbol

FYCO1

Name

FYVE and coiled-coil domain-containing protein 1

Pathway

map05132

Salmonella infection

Disease

H01202

Cataract

Brite

KEGG Orthology (KO) [BR:ko00001]
09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K21954  FYCO1; FYVE and coiled-coil domain-containing protein 1
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K21954  FYCO1; FYVE and coiled-coil domain-containing protein 1
Membrane trafficking [BR:ko04131]
Endosome - Lysosome transport
  Rab GTPases and associated proteins
   Rab associated proteins
    K21954  FYCO1; FYVE and coiled-coil domain-containing protein 1

Genes

HSA:	79443(FYCO1)

PTR:	100614690(FYCO1)

PPS:	100974660(FYCO1)

GGO:	101147558(FYCO1)

PON:	100446919(FYCO1)

PPYG:

129033471(FYCO1)

NLE:	100606509(FYCO1)

HMH:	116473554(FYCO1)

SSYN:

129483098

MCC:	713756(FYCO1)

MCF:	102135018(FYCO1)

MTHB:

126948579

MNI:	105480343(FYCO1)

CSAB:

103227528(FYCO1)

CATY:

105573598(FYCO1)

PANU:

101009824(FYCO1)

TGE:	112618893(FYCO1)

MLEU:

105540437(FYCO1)

RRO:	104671336(FYCO1)

RBB:	108517658(FYCO1)

TFN:	117080108(FYCO1)

PTEH:

111555610(FYCO1)

CANG:

105519333(FYCO1)

CJC:	100396608(FYCO1)

SBQ:	101052331(FYCO1)

CIMI:

108299534(FYCO1)

ANAN:

105729836(FYCO1)

CSYR:

103273925(FYCO1)

MMUR:

105874445(FYCO1)

LCAT:

123623094(FYCO1)

PCOQ:

105805172(FYCO1)

OGA:	100945696(FYCO1)

MMU:	17281(Fyco1)

MCAL:

110301190(Fyco1)

MPAH:

110327606(Fyco1)

RNO:	301085(Fyco1)

MCOC:

116073731(Fyco1)

ANU:	117693282(Fyco1)

ASYL:

127688331(Fyco1)

MUN:	110554129(Fyco1)

CGE:	100760712(Fyco1)

MAUA:

101835277(Fyco1)

PROB:

127234407(Fyco1)

PLEU:

114685953(Fyco1)

MORG:

121464227(Fyco1)

MFOT:

126501058

AAMP:

119808916(Fyco1)

NGI:	103733153(Fyco1)

HGL:	101726184(Fyco1)

CPOC:

100717495(Fyco1)

CCAN:

109695505(Fyco1)

DORD:

105996215(Fyco1)

DSP:	122100697(Fyco1)

DMER:

138823981(Fyco1)

PLOP:

125342414(Fyco1)

NCAR:

124969487

MMMA:

107145424(Fyco1)

ITI:	101963638(Fyco1)

OCU:

100349917

OPI:	101528040(FYCO1)

OCZ:	121165644(FYCO1)

TUP:	102497571(FYCO1)

GVR:	103595749(FYCO1)

CFA:	476649(FYCO1)

CLUD:

112666823(FYCO1)

VVP:	112912521(FYCO1)

VLG:	121494410(FYCO1)

NPO:	129521422(FYCO1)

AML:	100483562(FYCO1)

UMR:	103675128(FYCO1)

UAH:	113256782(FYCO1)

UAR:	123780078(FYCO1)

ELK:

111144047

LLV:

125081275

MPUF:

101683396(FYCO1)

MNP:	132011246(FYCO1)

MLK:	131823843(FYCO1)

NVS:	122909494(FYCO1)

ORO:	101374972(FYCO1)

EJU:	114196476(FYCO1)

ZCA:	113918884(FYCO1)

MLX:	118005720(FYCO1)

NSU:	110574539(FYCO1)

LWW:	102728341(FYCO1)

FCA:	101093003(FYCO1)

PYU:	121011098(FYCO1)

PCOO:

112852422(FYCO1)

PBG:	122487173(FYCO1)

PVIV:

125151560(FYCO1)

LRUF:

124525118

LGF:	123605566(FYCO1)

AJU:

106969114

PTG:	102953030(FYCO1)

PPAD:

109247703(FYCO1)

PUC:

125929281

PLEZ:

122214253(FYCO1)

HHV:	120229225(FYCO1)

BTA:	100139246(FYCO1)

BOM:	102266962(FYCO1)

BIU:	109576033(FYCO1)

BBUB:

102390155(FYCO1)

BBIS:

105004709(FYCO1)

CHX:	102180978(FYCO1)

OAS:	101104278(FYCO1)

BTAX:

128058823(FYCO1)

CSUM:

138087839(FYCO1)

ODA:	120868152(FYCO1)

CCAD:

122424273(FYCO1)

MREE:

136166899(FYCO1)

OVR:	110152388(FYCO1)

MBEZ:

129547753(FYCO1)

SSC:	100151740(FYCO1)

CFR:	102513448(FYCO1)

CBAI:

105061816(FYCO1)

CDK:	105091291(FYCO1)

VPC:	102529628(FYCO1)

BACU:

103005029(FYCO1)

BMUS:

118903300(FYCO1)

LVE:	103080277(FYCO1)

OOR:	101272906(FYCO1)

LALB:

132527086(FYCO1)

GMF:	115846553(FYCO1)

DDP:	132432234(FYCO1)

DLE:	111174475(FYCO1)

PCAD:

102991257(FYCO1)

PSIU:

116762252(FYCO1)

PPHC:

136128898(FYCO1)

NASI:

112403759(FYCO1)

ECB:	100054468(FYCO1)

EPZ:	103555070(FYCO1)

EAI:	106838393(FYCO1)

MYB:	102249461(FYCO1)

MYD:	102765484(FYCO1)

MMYO:

118668302(FYCO1)

MLF:	102436906(FYCO1)

MDT:	132215673(FYCO1)

MYUM:

138992755(FYCO1)

PKL:	118715580(FYCO1)

EFUS:

103297567(FYCO1)

MNA:	107529402(FYCO1)

DRO:	112309645(FYCO1)

SHON:

118976136(FYCO1)

AJM:	119037602(FYCO1)

PDIC:

114501926(FYCO1)

PHAS:

123830676(FYCO1)

MMF:	118633079(FYCO1)

PPAM:

129087609(FYCO1)

HAI:	109376736(FYCO1)

RFQ:	117036562(FYCO1)

PALE:

102890168(FYCO1)

PGIG:

120582268(FYCO1)

PVP:	105290377(FYCO1)

RAY:	107509093(FYCO1)

MJV:	108383890(FYCO1)

TOD:	119259127(FYCO1)

SARA:

101554149(FYCO1)

SFUM:

130037560(FYCO1)

SETR:

126014011(FYCO1)

LAV:	100660770(FYCO1)

TMU:

101358273

ETF:	101651264(FYCO1)

DNM:	101415495(FYCO1)

MDO:	100029942(FYCO1)

GAS:	123250241(FYCO1)

AFZ:

127538439

PCW:	110209098(FYCO1)

TVP:	118852301(FYCO1)

PBRV:

138161610(FYCO1)

MLAO:

141494540(FYCO1)

OAA:	100083089(FYCO1)

TACU:

119939938(FYCO1)

GGA:	428453(FYCO1)

PCOC:

116227187(FYCO1)

MGP:	104911550(FYCO1)

CJO:	107309363(FYCO1)

TPAI:

128086048(FYCO1)

LMUT:

125695918(FYCO1)

NMEL:

110393707(FYCO1)

APLA:

101802034(FYCO1)

ACYG:

106038344(FYCO1)

CATA:

118249610(FYCO1)

AFUL:

116485733(FYCO1)

TGU:	100219704(FYCO1)

LSR:	110471046(FYCO1)

SCAN:

103812983(FYCO1)

PMOA:

120503560(FYCO1)

OTC:	121337594(FYCO1)

PRUF:

121352919(FYCO1)

ATRC:

139591198(FYCO1)

GFR:	102045472(FYCO1)

FAB:	101818289(FYCO1)

OMA:	130249065(FYCO1)

PHI:	102104262(FYCO1)

PMAJ:

107200289(FYCO1)

CCAE:

111923564(FYCO1)

CCW:	104688998(FYCO1)

CBRC:

103615801(FYCO1)

ACOE:

138106607(FYCO1)

ETL:	114064226(FYCO1)

ZAB:	102063286(FYCO1)

ZLE:	135443920(FYCO1)

ACHL:

103799146(FYCO1)

SVG:	106854462(FYCO1)

MMEA:

130580031(FYCO1)

HRT:	120762786(FYCO1)

SATI:

136362470(FYCO1)

CCIC:

134054008(FYCO1)

FPG:	101923782(FYCO1)

FCH:	102058574(FYCO1)

CCRI:

104155994

NNT:	104411566(FYCO1)

SHAB:

115619912(FYCO1)

ACUN:

113476258(FYCO1)

TALA:

104363265(FYCO1)

ACHC:

115338995(FYCO1)

HALD:

104318057(FYCO1)

HLE:	104828397(FYCO1)

AGEN:

126045387

HHAR:

128145103(FYCO1)

GCL:

127013045

CSTI:

104553228(FYCO1)

LDI:	104354457(FYCO1)

MNB:	103768812(FYCO1)

DPUB:

104298290(FYCO1)

PPUS:

135189341(FYCO1)

AVIT:

104280296

BRHI:

104496976(FYCO1)

EGZ:	104127516(FYCO1)

NNI:	104012120(FYCO1)

PCRI:

104034628(FYCO1)

PCAO:

104050147(FYCO1)

PADL:

103922995(FYCO1)

AFOR:

103899714(FYCO1)

FGA:	104081628(FYCO1)

CBOR:

142079289(FYCO1)

GSTE:

104257628

CBOY:

140648184(FYCO1)

MAME:

142405628(FYCO1)

CLV:	102084742(FYCO1)

CNIC:

135985135(FYCO1)

MUI:	104537425(FYCO1)

PGUU:

104469992(FYCO1)

PLET:

104614759(FYCO1)

EHS:	104509974(FYCO1)

CMAC:

104481466

CUCA:

104067617(FYCO1)

TEO:	104372653(FYCO1)

BREG:

104635716

OHA:	104336877(FYCO1)

ACAR:

104518998(FYCO1)

CPEA:

104397442(FYCO1)

CVF:	104295283(FYCO1)

RTD:	128904928(FYCO1)

CRID:

134511432(FYCO1)

LMIC:

141738971(FYCO1)

AAM:	106491239(FYCO1)

AROW:

112977960(FYCO1)

NPD:	112943609(FYCO1)

TGT:	104571914(FYCO1)

DNE:	112979656(FYCO1)

SCAM:

104152484(FYCO1)

ASN:	102387425(FYCO1)

AMJ:	102564876(FYCO1)

CPOO:

109311488(FYCO1)

GGN:	109291768(FYCO1)

PSS:	102459665(FYCO1)

CIZ:	142009749(FYCO1)

CMY:	102943133(FYCO1)

CCAY:

125631720(FYCO1)

DCC:	119850897(FYCO1)

CPIC:

101937297(FYCO1)

TST:	117872475(FYCO1)

CABI:

116838179(FYCO1)

MRV:	120396955(FYCO1)

ACS:	100554795(rufy4) 100559283(fyco1)

ASAO:

132778616(FYCO1)

PVT:	110084882(FYCO1) 110085208(RUFY4)

SUND:

121919896(RUFY4) 121933024(FYCO1)

PBI:	103054392 103063222

PMUR:

107293839(FYCO1)

CTIG:

120304970(FYCO1) 120307912(RUFY4)

TSR:	106542446(FYCO1) 106548978(RUFY4)

PGUT:

117656125 117668059(RUFY4) 132710226

APRI:

131198576(FYCO1)

PTEX:

113447568(FYCO1)

NSS:	113419211(FYCO1)

VKO:	123017650(FYCO1) 123027562(RUFY4)

PMUA:

114603397(RUFY4) 114607398(FYCO1)

PRAF:

128424049(FYCO1)

ZVI:	118091218(RUFY4) 118091779(FYCO1)

HCG:	128329095(FYCO1)

GJA:	107109414(RUFY4) 107111415(FYCO1)

STOW:

125425780(RUFY4) 125440950(FYCO1)

EMC:	129337471(FYCO1)

PWL:	138267454(FYCO1)

MUO:	115470255(FYCO1)

GSH:	117353904(FYCO1)

DRE:	100329883(fyco1b) 565649(fyco1a)

SRX:	107713630 107738442 107754903 107757827

SANH:

107655871 107663534 107664203

SGH:	107558744 107590459 107599271 107600249

CCAR:

109057814 109083243 109088304 109103600

CAUA:

113041292 113065650 113078250 113079948 113096948 113113127

CGIB:

127936241 127944582 127951140 128012113

PTET:

122332795(fyco1a) 122362831(fyco1b)

LROH:

127154676(fyco1a) 127180449(fyco1b)

GRF:	141344364(fyco1b)

OMC:	131523280(fyco1b) 131531607(fyco1a)

PPRM:

120463457(fyco1a) 120482385(fyco1b)

RKG:	130076213 130105565(fyco1b)

MAMB:

125250113(fyco1b) 125259531(fyco1a)

CIDE:

127498498 127504701

CERY:

137003138(fyco1b) 137009074(fyco1a)

MASI:

127418734 127419974 127443137

TROS:

130545191(fyco1a) 130554749(fyco1b)

TDW:	130409292(fyco1a) 130418358(fyco1b)

MANU:

129430684(fyco1a) 129441678(fyco1b)

PDAB:

135767087(fyco1b) 135775164(fyco1a)

IPU:	108275732(fyco1a) 108280757(fyco1b)

IFU:	128619262(fyco1a) 128624137(fyco1b)

PHYP:

113530562(fyco1) 113546343

SMEO:

124398945(fyco1a) 124403032(fyco1b)

TFD:	113641888(fyco1a) 113655527(fyco1b)

TVC:	132844755(fyco1b) 132861971(fyco1a)

CGAR:

128509920(fyco1a) 128513475(fyco1b)

NGRA:

132871843(fyco1b) 132896671(fyco1a)

TRN:	134302291(fyco1b) 134333598(fyco1a)

AMEX:

103039728(fyco1a) 103045023(fyco1b)

CMAO:

118797093(fyco1b) 118822818(fyco1a)

EEE:	113584355 113589308

CHAR:

105906951(fyco1b) 105907113

SPIL:

134061170(fyco1b) 134101981

ASAD:

121677727 121717130(fyco1b)

TRU:	101067070 101072439

TFS:	130528654(fyco1a) 130538648

TNG:	GSTEN00012646G001 GSTEN00034497G001

LCO:	104917754 104918454(fyco1)

NCC:	104946561 104956504(fyco1)

TBEN:

117488356 117495186(fyco1a)

CGOB:

115007020 115022527

PGEO:

117445186(fyco1a) 117461762(fyco1b)

GACU:

117550937(fyco1a)

EMAC:

134866028 134869517(fyco1a)

ELY:	117254098(fyco1a) 117272195

EFO:	125895554(fyco1a) 125902530

PLEP:

121938320(fyco1a) 121951227

SLUC:

116046202 116063305(fyco1a)

ECRA:

117950417(fyco1a) 117954198

ESP:	116695391(fyco1) 116698510

PFLV:

114561345(fyco1) 114564985

GAT:	120816096 120823790(fyco1a)

PPUG:

119209437 119216473(fyco1a)

AFB:	129089081 129094434(fyco1a)

CLUM:

117729292(fyco1a) 117746465

PSWI:

130193953(fyco1a) 130198529

CANA:

137781288(fyco1b) 137794472(fyco1a)

CVE:	137870194(fyco1a) 137892673(fyco1b)

MSAM:

119900805(fyco1a) 119901920

SCHU:

122877365(fyco1a) 122886528

CUD:	121512003(fyco1a) 121520170(fyco1b)

SPUL:

138606883(fyco1a) 138611811(fyco1b)

LMIX:

132960356(fyco1a) 132979311

HTC:	141788920(fyco1a) 141804160(fyco1b)

ALAT:

119011450 119028581(fyco1a)

ASTR:

137598759(fyco1a) 137612864(fyco1b)

MZE:	101469042 101473040

ONL:	100690889 100690901

OAU:	116315300 116317757(fyco1a)

OLA:	101174497(fyco1)

OML:	112147544(fyco1b) 112150262(fyco1a)

CSAI:

133452848 133458340(fyco1a)

XMA:	102218511(fyco1) 102230637

XCO:	114146893 114150286

XHE:	116722064 116725700

PRET:

103463582(fyco1) 103479840

PFOR:

103135699 103142578

PLAI:

106959193 106963837(fyco1)

PMEI:

106904412 106916802

GAF:	122838522(fyco1a) 122841077

PPRL:

129361885 129374136(fyco1a)

CVG:	107081664 107081974

CTUL:

119773689(fyco1a) 119781272

GMU:	124870096 124874206(fyco1a)

NFU:	107383801 107393229

KMR:	108230784(fyco1a) 108232959

ALIM:

106513898(fyco1) 106524534

NWH:	119415184 119430674(fyco1a)

AOCE:

111570414 111584302(fyco1a)

EJA:	138198716(fyco1a) 138203103(fyco1b)

BFRE:

138617368(fyco1b) 138618937(fyco1a)

MCEP:

125009472(fyco1a) 125011261

CSEM:

103396406 103398058

POV:	109625778(fyco1) 109637103

SSEN:

122775087 122780645(fyco1a)

SSOE:

131463592 131465527(fyco1a)

HHIP:

117759995(fyco1a) 117778275

HSP:	118118051 124854644(fyco1a)

PPLT:

128448600(fyco1a) 128454799

SMAU:

118311143(fyco1b) 118317856(fyco1a)

LCF:	108877414 108883288

SDU:	111231173 111232142

SLAL:

111656344(fyco1) 111657012

XGL:	120790750(fyco1a) 120799066

HCQ:	109524064 109532271(fyco1)

SSCV:

125971213(fyco1a) 125984995

SBIA:

133503205(fyco1a) 133510687

PEE:	133406619(fyco1a) 133412088

PTAO:

133481192(fyco1a) 133488988(fyco1b)

BPEC:

110164172 110167794

ENY:	140354403(fyco1a) 140356098(fyco1b)

MALB:

109955370 109964029(fyco1)

BSPL:

114844599 114853928(fyco1a)

SJO:	128361660(fyco1a) 128369130

SSCO:

133984693(fyco1a) 133991066

TTY:	137187889(fyco1a) 137194371(fyco1b)

GMH:	115549502 115555641(fyco1)

SASA:

106574038 106597278 106613556

STRU:

115151587 115158030 115170251

OTW:	112250665 112252057

OMY:	110485093 110509177 110524072

OGO:	123997394 123997562 124040707

ONE:	115108110(fyco1) 115122321

OKI:	109885482 109889062 109902304

OKE:	118387451 118401526

OMM:	135512583 135524718 135539341

OCLA:

139375761 139409009 139423385

SALP:

111952405 111975752 112075261

SNH:	120037616 120053666 120054638

SFON:

129811018 129867386

CCLU:

121533726 121576437

ELS:	105007479 105011441(fyco1)

OEP:	134013093(fyco1a) 134036090

SFM:	108927474 108931026

PKI:	111845919(fyco1) 111860738

AANG:

118225933(fyco1a) 118232828

AROT:

135254172 135260283

CCOG:

133126885(fyco1a) 133136345

LOC:	102687770(fyco1)

PSPA:

121313081 121314557

ARUT:

117394725 117400569

PSEX:

120529572

LCM:	102346764(RUFY4) 102360681(FYCO1)

CMK:	103183382(fyco1a)

RTP:	109920095(fyco1a) 109935308

CPLA:

122564486(fyco1a)

HOC:	132832306(fyco1a)

SCAU:

119965819(fyco1a)

LERI:

129710875(fyco1a)

HAKA:

140713758

PMRN:

116940862(FYCO1)

LRJ:

133344630

BFO:

118403495

BBEL:

109470404

CIN:	751569(zf(fyve)-6)

SCLV:

SPU:

LVG:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

SKO:

PFLL:

DPX:	DAPPUDRAFT_224701

DMK:

DPZ:

HAME:

PCLA:

PTRU:

DSV:

RSAN:

RMP:

CSCU:

SDM:

PCAN:

LSAX:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:	115210310 115210536

LJP:

LAK:

LLON:

NVE:

EPA:

ATEN:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

AQU:

SRE:	PTSG_13141

» show all

Reference

PMID:20100911

Authors

Pankiv S, Alemu EA, Brech A, Bruun JA, Lamark T, Overvatn A, Bjorkoy G, Johansen T

Title

FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport.

Journal

J Cell Biol 188:253-69 (2010)
DOI:10.1083/jcb.200907015

Sequence

[hsa:79443]

LinkDB

DBGET integrated database retrieval system