KEGG   PATHWAY: cgib00310
Entry
cgib00310                   Pathway                                
Name
Lysine degradation - Carassius gibelio (silver crucian carp)
Class
Metabolism; Amino acid metabolism
Pathway map
cgib00310  Lysine degradation
cgib00310

Module
cgib_M00032  Lysine degradation, lysine => saccharopine => acetoacetyl-CoA [PATH:cgib00310]
Other DBs
GO: 0006554
Organism
Carassius gibelio (silver crucian carp) [GN:cgib]
Gene
127953010  alpha-aminoadipic semialdehyde synthase, mitochondrial-like [KO:K14157] [EC:1.5.1.8 1.5.1.9]
127947095  alpha-aminoadipic semialdehyde synthase, mitochondrial [KO:K14157] [EC:1.5.1.8 1.5.1.9]
127966182  alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
128017423  kynurenine/alpha-aminoadipate aminotransferase, mitochondrial [KO:K00825] [EC:2.6.1.7 2.6.1.39]
127946691  2-oxoadipate dehydrogenase complex component E1-like [KO:K15791] [EC:1.2.4.-]
128014587  2-oxoadipate dehydrogenase complex component E1 [KO:K15791] [EC:1.2.4.-]
127933208  dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial [KO:K00658] [EC:2.3.1.61]
127975807  dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial-like [KO:K00658] [EC:2.3.1.61]
127947448  dihydrolipoyl dehydrogenase, mitochondrial-like [KO:K00382] [EC:1.8.1.4]
128014534  dihydrolipoyl dehydrogenase, mitochondrial [KO:K00382] [EC:1.8.1.4]
127954454  glutaryl-CoA dehydrogenase b isoform X1 [KO:K00252] [EC:1.3.8.6]
127959141  glutaryl-CoA dehydrogenase, mitochondrial-like [KO:K00252] [EC:1.3.8.6]
128016128  glutaryl-CoA dehydrogenase a isoform X1 [KO:K00252] [EC:1.3.8.6]
127933597  trifunctional enzyme subunit alpha, mitochondrial-like [KO:K07515] [EC:4.2.1.17 1.1.1.211]
127976195  trifunctional enzyme subunit alpha, mitochondrial-like [KO:K07515] [EC:4.2.1.17 1.1.1.211]
127938398  hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha a [KO:K07515] [EC:4.2.1.17 1.1.1.211]
127965244  peroxisomal bifunctional enzyme [KO:K07514] [EC:4.2.1.17 1.1.1.35 5.3.3.8]
127970788  enoyl-CoA hydratase, mitochondrial [KO:K07511] [EC:4.2.1.17]
128026219  enoyl-CoA hydratase, mitochondrial-like [KO:K07511] [EC:4.2.1.17]
127948991  hydroxyacyl-coenzyme A dehydrogenase, mitochondrial [KO:K00022] [EC:1.1.1.35]
127983677  acetyl-CoA acetyltransferase, cytosolic [KO:K00626] [EC:2.3.1.9]
127966334  acetyl-CoA acetyltransferase, mitochondrial [KO:K00626] [EC:2.3.1.9]
127938298  acetyl-CoA acetyltransferase, cytosolic-like [KO:K00626] [EC:2.3.1.9]
128020971  acetyl-CoA acetyltransferase, mitochondrial-like [KO:K00626] [EC:2.3.1.9]
127987891  hydroxylysine kinase [KO:K18201] [EC:2.7.1.81]
127972685  5-phosphohydroxy-L-lysine phospho-lyase [KO:K18202] [EC:4.2.3.134]
127972773  peroxisomal sarcosine oxidase isoform X1 [KO:K00306] [EC:1.5.3.1 1.5.3.7]
127970047  calmodulin-lysine N-methyltransferase-like [KO:K18826] [EC:2.1.1.60]
128026311  calmodulin-lysine N-methyltransferase isoform X1 [KO:K18826] [EC:2.1.1.60]
127972680  histone-lysine N-methyltransferase 2A isoform X1 [KO:K09186] [EC:2.1.1.354]
128029223  histone-lysine N-methyltransferase 2A-like isoform X1 [KO:K09186] [EC:2.1.1.354]
127945167  histone-lysine N-methyltransferase 2D-like [KO:K09187] [EC:2.1.1.354]
128011063  histone-lysine N-methyltransferase 2D-like isoform X1 [KO:K09187] [EC:2.1.1.354]
127946125  histone-lysine N-methyltransferase 2C-like isoform X1 [KO:K09188] [EC:2.1.1.354]
127950906  histone-lysine N-methyltransferase 2C-like isoform X1 [KO:K09188] [EC:2.1.1.354]
128013513  histone-lysine N-methyltransferase 2C isoform X1 [KO:K09188] [EC:2.1.1.354]
128025086  histone-lysine N-methyltransferase 2C-like isoform X1 [KO:K09188] [EC:2.1.1.354]
127979018  histone-lysine N-methyltransferase 2A-like isoform X1 [KO:K14959] [EC:2.1.1.354]
127973165  histone-lysine N-methyltransferase 2A [KO:K14959] [EC:2.1.1.354]
127935245  histone-lysine N-methyltransferase 2B isoform X1 [KO:K14959] [EC:2.1.1.354]
128028980  histone-lysine N-methyltransferase 2B-like [KO:K14959] [EC:2.1.1.354]
127973055  inactive histone-lysine N-methyltransferase 2E isoform X1 [KO:K09189] [EC:2.1.1.354]
127956623  LOW QUALITY PROTEIN: inactive histone-lysine N-methyltransferase 2E-like [KO:K09189] [EC:2.1.1.354]
127963529  histone-lysine N-methyltransferase SETD1B-A [KO:K11422] [EC:2.1.1.354]
127953796  histone-lysine N-methyltransferase SETD1A-like isoform X1 [KO:K11422] [EC:2.1.1.354]
127966568  histone-lysine N-methyltransferase SETD1B-A-like isoform X1 [KO:K11422] [EC:2.1.1.354]
127950214  histone-lysine N-methyltransferase SETD1A-like isoform X1 [KO:K11422] [EC:2.1.1.354]
128020707  histone-lysine N-methyltransferase SETD1B-A isoform X1 [KO:K11422] [EC:2.1.1.354]
127971159  histone-lysine N-methyltransferase SETD7 [KO:K11431] [EC:2.1.1.364]
128027536  histone-lysine N-methyltransferase SETD7-like [KO:K11431] [EC:2.1.1.364]
127969162  histone-lysine N-methyltransferase PRDM9-like [KO:K20796] [EC:2.1.1.354]
128024935  histone-lysine N-methyltransferase PRDM9-like isoform X1 [KO:K20796] [EC:2.1.1.354]
127979019  histone-lysine N-methyltransferase ASH1L-like [KO:K06101] [EC:2.1.1.354]
127934925  histone-lysine N-methyltransferase ASH1L-like [KO:K06101] [EC:2.1.1.354]
127962928  histone-lysine N-methyltransferase SMYD1b isoform X1 [KO:K11426] [EC:2.1.1.354 2.1.1.357]
127933367  N-lysine methyltransferase SMYD2-A-like [KO:K11426] [EC:2.1.1.354 2.1.1.357]
127958903  histone-lysine N-methyltransferase SMYD1-like [KO:K11426] [EC:2.1.1.354 2.1.1.357]
127938052  N-lysine methyltransferase SMYD2-B [KO:K11426] [EC:2.1.1.354 2.1.1.357]
127976654  N-lysine methyltransferase SMYD2-A [KO:K11426] [EC:2.1.1.354 2.1.1.357]
128031789  histone-lysine N-methyltransferase SMYD3 [KO:K11426] [EC:2.1.1.354 2.1.1.357]
127992783  histone-lysine N-methyltransferase SMYD1a [KO:K11426] [EC:2.1.1.354 2.1.1.357]
127963667  histone-lysine N-methyltransferase SUV39H1-like [KO:K11419] [EC:2.1.1.355]
127963948  histone-lysine N-methyltransferase SUV39H1-A [KO:K11419] [EC:2.1.1.355]
128018622  histone-lysine N-methyltransferase SUV39H1-like [KO:K11419] [EC:2.1.1.355]
127941610  histone-lysine N-methyltransferase EHMT1-like isoform X1 [KO:K11420] [EC:2.1.1.355]
127978942  histone-lysine N-methyltransferase EHMT2 isoform X1 [KO:K11420] [EC:2.1.1.355]
127958362  histone-lysine N-methyltransferase EHMT1a isoform X1 [KO:K11420] [EC:2.1.1.355]
127985727  histone-lysine N-methyltransferase EHMT1-like isoform X1 [KO:K11420] [EC:2.1.1.355]
128008940  histone-lysine N-methyltransferase EHMT1-like isoform X1 [KO:K11420] [EC:2.1.1.355]
127979020  histone-lysine N-methyltransferase SETDB1-A-like isoform X1 [KO:K11421] [EC:2.1.1.366]
127974706  histone-lysine N-methyltransferase SETDB1-B isoform X1 [KO:K11421] [EC:2.1.1.366]
127935667  histone-lysine N-methyltransferase SETDB1-A-like isoform X1 [KO:K11421] [EC:2.1.1.366]
128030992  histone-lysine N-methyltransferase SETDB1-B-like isoform X1 [KO:K11421] [EC:2.1.1.366]
127948893  histone-lysine N-methyltransferase SETDB2 [KO:K18494] [EC:2.1.1.355]
127964044  PR domain zinc finger protein 2-like isoform X1 [KO:K11432] [EC:2.1.1.355]
127968197  PR domain zinc finger protein 2-like isoform X1 [KO:K11432] [EC:2.1.1.355]
128022285  PR domain zinc finger protein 2-like isoform X1 [KO:K11432] [EC:2.1.1.355]
128018573  PR domain zinc finger protein 2-like [KO:K11432] [EC:2.1.1.355]
127951387  histone-lysine N-methyltransferase EZH1-like [KO:K17451] [EC:2.1.1.356]
127952888  histone-lysine N-methyltransferase EZH1-like isoform X1 [KO:K17451] [EC:2.1.1.356]
127946210  histone-lysine N-methyltransferase EZH2-like isoform X1 [KO:K11430] [EC:2.1.1.356]
128013173  histone-lysine N-methyltransferase EZH2 isoform X1 [KO:K11430] [EC:2.1.1.356]
128022146  histone-lysine N-methyltransferase SETMAR-like [KO:K11433] [EC:2.1.1.357]
127971584  histone-lysine N-methyltransferase, H3 lysine-36 specific-like isoform X1 [KO:K15588] [EC:2.1.1.357]
127985754  histone-lysine N-methyltransferase NSD2 isoform X1 [KO:K15588] [EC:2.1.1.357]
128027578  histone-lysine N-methyltransferase NSD2-like isoform X1 [KO:K15588] [EC:2.1.1.357]
127969808  histone-lysine N-methyltransferase NSD2-like isoform X1 [KO:K11424] [EC:2.1.1.357]
128026354  histone-lysine N-methyltransferase NSD2-like isoform X1 [KO:K11424] [EC:2.1.1.357]
127966832  histone-lysine N-methyltransferase NSD3-like isoform X1 [KO:K11425] [EC:2.1.1.370 2.1.1.371]
128021289  histone-lysine N-methyltransferase NSD3-like isoform X1 [KO:K11425] [EC:2.1.1.370 2.1.1.371]
127975534  histone-lysine N-methyltransferase SETD2 isoform X1 [KO:K11423] [EC:2.1.1.359]
127969714  histone-lysine N-methyltransferase SETD2-like [KO:K11423] [EC:2.1.1.359]
128030804  histone-lysine N-methyltransferase SETD2-like [KO:K11423] [EC:2.1.1.359]
127942988  histone-lysine N-methyltransferase, H3 lysine-79 specific-like isoform X1 [KO:K11427] [EC:2.1.1.360]
127987341  histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1 [KO:K11427] [EC:2.1.1.360]
127966870  N-lysine methyltransferase KMT5A-A-like [KO:K11428] [EC:2.1.1.361]
127958296  lysine methyltransferase 5Ab [KO:K11428] [EC:2.1.1.361]
127990317  N-lysine methyltransferase KMT5A-A-like [KO:K11428] [EC:2.1.1.361]
128020806  N-lysine methyltransferase KMT5A-A-like [KO:K11428] [EC:2.1.1.361]
127963374  putative histone-lysine N-methyltransferase PRDM6 [KO:K20795] [EC:2.1.1.361]
128018085  putative histone-lysine N-methyltransferase PRDM6 [KO:K20795] [EC:2.1.1.361]
127934317  histone-lysine N-methyltransferase KMT5B [KO:K11429] [EC:2.1.1.362]
127977574  histone-lysine N-methyltransferase KMT5B-like [KO:K11429] [EC:2.1.1.362]
127972606  MDS1 and EVI1 complex locus protein EVI1-A isoform X1 [KO:K04462] [EC:2.1.1.367]
128028962  MDS1 and EVI1 complex locus protein EVI1-A-like isoform X1 [KO:K04462] [EC:2.1.1.367]
127963231  histone-lysine N-methyltransferase PRDM16 isoform X1 [KO:K22410] [EC:2.1.1.367]
128018185  histone-lysine N-methyltransferase PRDM16-like isoform X1 [KO:K22410] [EC:2.1.1.367]
127942191  trimethyllysine dioxygenase, mitochondrial-like [KO:K00474] [EC:1.14.11.8]
127986452  trimethyllysine dioxygenase, mitochondrial-like [KO:K00474] [EC:1.14.11.8]
127941997  aldehyde dehydrogenase family 3 member A2-like [KO:K00128] [EC:1.2.1.3]
127953696  aldehyde dehydrogenase family 16 member A1-like isoform X1 [KO:K00128] [EC:1.2.1.3]
127972709  aldehyde dehydrogenase family 3 member A2 [KO:K00128] [EC:1.2.1.3]
127972710  aldehyde dehydrogenase family 3 member A2a [KO:K00128] [EC:1.2.1.3]
127957401  aldehyde dehydrogenase, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
127949543  aldehyde dehydrogenase family 16 member A1 isoform X1 [KO:K00128] [EC:1.2.1.3]
127985641  aldehyde dehydrogenase family 3 member A2-like [KO:K00128] [EC:1.2.1.3]
127963451  4-trimethylaminobutyraldehyde dehydrogenase A-like [KO:K00149] [EC:1.2.1.47 1.2.1.3]
127951035  4-trimethylaminobutyraldehyde dehydrogenase B isoform X1 [KO:K00149] [EC:1.2.1.47 1.2.1.3]
128018744  4-trimethylaminobutyraldehyde dehydrogenase A [KO:K00149] [EC:1.2.1.47 1.2.1.3]
127961459  gamma-butyrobetaine dioxygenase-like [KO:K00471] [EC:1.14.11.1]
128016894  gamma-butyrobetaine dioxygenase-like [KO:K00471] [EC:1.14.11.1]
127964026  procollagen-lysine,2-oxoglutarate 5-dioxygenase 1-like [KO:K00473] [EC:1.14.11.4]
128018189  procollagen-lysine,2-oxoglutarate 5-dioxygenase 1-like [KO:K00473] [EC:1.14.11.4]
127946380  procollagen-lysine,2-oxoglutarate 5-dioxygenase 2-like isoform X1 [KO:K13645] [EC:1.14.11.4]
128013294  procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 isoform X1 [KO:K13645] [EC:1.14.11.4]
128011419  multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [KO:K13646] [EC:1.14.11.4 2.4.1.50 2.4.1.66]
127952079  procollagen galactosyltransferase 1 [KO:K11703] [EC:2.4.1.50]
127953114  procollagen galactosyltransferase 1-like [KO:K11703] [EC:2.4.1.50]
127963885  procollagen galactosyltransferase 2-like [KO:K11703] [EC:2.4.1.50]
127966275  probable inactive glycosyltransferase 25 family member 3 [KO:K11703] [EC:2.4.1.50]
127949449  procollagen galactosyltransferase 1 [KO:K11703] [EC:2.4.1.50]
127950920  procollagen galactosyltransferase 2 [KO:K11703] [EC:2.4.1.50]
128021426  probable inactive glycosyltransferase 25 family member 3 [KO:K11703] [EC:2.4.1.50]
128026168  procollagen galactosyltransferase 1-like [KO:K11703] [EC:2.4.1.50]
128018781  procollagen galactosyltransferase 2-like [KO:K11703] [EC:2.4.1.50]
Compound
C00024  Acetyl-CoA
C00026  2-Oxoglutarate
C00037  Glycine
C00042  Succinate
C00047  L-Lysine
C00068  Thiamin diphosphate
C00136  Butanoyl-CoA
C00164  Acetoacetate
C00322  2-Oxoadipate
C00332  Acetoacetyl-CoA
C00408  L-Pipecolate
C00431  5-Aminopentanoate
C00449  N6-(L-1,3-Dicarboxypropyl)-L-lysine
C00450  (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate
C00487  Carnitine
C00489  Glutarate
C00527  Glutaryl-CoA
C00739  D-Lysine
C00877  Crotonoyl-CoA
C00956  L-2-Aminoadipate
C00990  5-Aminopentanamide
C01087  (R)-2-Hydroxyglutarate
C01142  (3S)-3,6-Diaminohexanoate
C01144  (S)-3-Hydroxybutanoyl-CoA
C01149  4-Trimethylammoniobutanal
C01181  4-Trimethylammoniobutanoate
C01186  (3S,5S)-3,5-Diaminohexanoate
C01211  Procollagen 5-hydroxy-L-lysine
C01259  (3S)-3-Hydroxy-N6,N6,N6-trimethyl-L-lysine
C01672  Cadaverine
C02188  Protein lysine
C02727  N6-Acetyl-L-lysine
C03087  5-Acetamidopentanoate
C03196  (S)-2-Hydroxyglutarate
C03239  6-Amino-2-oxohexanoate
C03273  5-Oxopentanoate
C03366  5-Phosphooxy-L-lysine
C03656  (S)-5-Amino-3-oxohexanoic acid
C03793  N6,N6,N6-Trimethyl-L-lysine
C04020  D-Lysopine
C04076  L-2-Aminoadipate 6-semialdehyde
C04092  Delta1-Piperideine-2-carboxylate
C04487  5-(D-Galactosyloxy)-L-lysine-procollagen
C05161  (2R,5S)-2,5-Diaminohexanoate
C05231  L-3-Aminobutyryl-CoA
C05544  Protein N6-methyl-L-lysine
C05545  Protein N6,N6-dimethyl-L-lysine
C05546  Protein N6,N6,N6-trimethyl-L-lysine
C05548  6-Acetamido-2-oxohexanoate
C05825  2-Amino-5-oxohexanoate
C06157  [Dihydrolipoyllysine-residue succinyltransferase] S-glutaryldihydrolipoyllysine
C12455  5-Aminopentanal
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16741  L-Hydroxylysine
C22667  4-Carboxy-1-hydroxybutyryl-ThPP
Reference
PMID:11802770
  Authors
Vaz FM, Wanders RJ.
  Title
Carnitine biosynthesis in mammals.
  Journal
Biochem J 361:417-29 (2002)
DOI:10.1042/bj3610417
Reference
PMID:1682209
  Authors
Large PJ, Robertson A.
  Title
The route of lysine breakdown in Candida tropicalis.
  Journal
FEMS Microbiol Lett 66:209-13 (1991)
DOI:10.1111/j.1574-6968.1990.tb03998.x
Related
pathway
cgib00020  Citrate cycle (TCA cycle)
cgib00780  Biotin metabolism
KO pathway
ko00310   
LinkDB

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