KEGG   PATHWAY: npd04820
Entry
npd04820                    Pathway                                
Name
Cytoskeleton in muscle cells - Nothoprocta perdicaria (Chilean tinamou)
Class
Cellular Processes; Cell motility
Pathway map
npd04820  Cytoskeleton in muscle cells
npd04820

Organism
Nothoprocta perdicaria (Chilean tinamou) [GN:npd]
Gene
112942316  CAPZA2; F-actin-capping protein subunit alpha-2 [KO:K10364]
112942470  SPTBN5; spectrin beta chain, non-erythrocytic 5 [KO:K06115]
112942521  CAPN3; calpain-3 isoform X1 [KO:K08573] [EC:3.4.22.54]
112942567  SGCB; beta-sarcoglycan [KO:K12566]
112942624  PDLIM3; PDZ and LIM domain protein 3 isoform X1 [KO:K23353]
112942668  SGCZ; zeta-sarcoglycan [KO:K27062]
112942724  COL3A1; collagen alpha-1(III) chain [KO:K19720]
112942733  ITGAV; integrin alpha-V [KO:K06487]
112942747  COL5A2; collagen alpha-2(V) chain [KO:K19721]
112942773  LBR; lamin-B receptor [KO:K19532] [EC:1.3.1.70]
112942813  SPTBN1; spectrin beta chain, non-erythrocytic 1 [KO:K06115]
112942863  MYOM2; myomesin-2 [KO:K24495]
112942975  DAAM2; disheveled-associated activator of morphogenesis 2 isoform X1 [KO:K04512]
112943176  DIAPH3; protein diaphanous homolog 3 [KO:K05745]
112943342  FHL2; four and a half LIM domains protein 2 [KO:K14380]
112943441  SYNPO2; synaptopodin-2 [KO:K24066]
112943443  MYOZ2; myozenin-2 [KO:K26050]
112943447  ANK2; ankyrin-2 isoform X1 [KO:K09255]
112943475  [KO:K12314]
112943502  AMPD3; AMP deaminase 3 [KO:K01490] [EC:3.5.4.6]
112943821  MYBPC3; myosin-binding protein C, cardiac-type [KO:K12568]
112943895  TPM4; tropomyosin alpha-4 chain [KO:K10375]
112943918  LMNB2; lamin-B2 [KO:K07611]
112943952  FBN3; fibrillin-3 isoform X1 [KO:K23342]
112944104  [KO:K24495]
112944127  LAMA1; laminin subunit alpha-1 [KO:K05637]
112944142  DCN; decorin [KO:K04660]
112944169  CAPZA3; LOW QUALITY PROTEIN: F-actin-capping protein subunit alpha-3 [KO:K10364]
112944218  TRIM55; tripartite motif-containing protein 55 [KO:K10654]
112944488  COL4A6; collagen alpha-6(IV) chain [KO:K06237]
112944495  VCAN; versican core protein isoform X1 [KO:K06793]
112944518  DIAPH2; protein diaphanous homolog 2 isoform X1 [KO:K05741]
112944559  COL4A5; collagen alpha-5(IV) chain isoform X1 [KO:K06237]
112944604  AMPD2; AMP deaminase 2 [KO:K01490] [EC:3.5.4.6]
112944615  CAPZA1; F-actin-capping protein subunit alpha-1 [KO:K10364]
112944780  XIRP2; xin actin-binding repeat-containing protein 2 [KO:K27381]
112945128  COL4A1; collagen alpha-1(IV) chain [KO:K06237]
112945133  COL4A2; collagen alpha-2(IV) chain isoform X1 [KO:K06237]
112945242  TNNI2; troponin I, fast skeletal muscle [KO:K12043]
112945249  TNNT3; troponin T, fast skeletal muscle [KO:K12046]
112945270  ACTG1; actin, cytoplasmic 2 [KO:K05692]
112945688  MYL9; myosin regulatory light polypeptide 9 [KO:K12755]
112945701  NID1; nidogen-1 [KO:K06826]
112945702  ACTN2; alpha-actinin-2 isoform X1 [KO:K21073]
112945847  ITGA2; integrin alpha-2 [KO:K06481]
112945854  ITGA1; integrin alpha-1 [KO:K06480]
112946223  COL24A1; collagen alpha-1(XXIV) chain [KO:K19721]
112946366  FMNL2; formin-like protein 2 isoform X1 [KO:K23957]
112946509  THBS4; thrombospondin-4 [KO:K04659]
112946621  MYBPC1; myosin-binding protein C, slow-type [KO:K12557]
112946639  CSRP2; cysteine and glycine-rich protein 2 [KO:K09377]
112946853  COMP; cartilage oligomeric matrix protein [KO:K04659]
112946984  FHL1; four and a half LIM domains protein 1 isoform X1 [KO:K14365]
112947007  ATP1B4; protein ATP1B4 [KO:K01540]
112947226  LAMA2; laminin subunit alpha-2 [KO:K05637]
112947307  ITGA8; integrin alpha-8 [KO:K06584]
112947345  [KO:K25865]
112947391  VIM; vimentin [KO:K07606]
112947415  SNTB1; beta-1-syntrophin [KO:K24064]
112947511  SNTB2; beta-2-syntrophin [KO:K24064]
112947561  MYL3; myosin light chain 3 [KO:K12749]
112947734  SUN2; SUN domain-containing protein 2 [KO:K19347]
112947868  [KO:K06237]
112947896  ATP1B3; sodium/potassium-transporting ATPase subunit beta-3 [KO:K01540]
112947929  COL4A4; collagen alpha-4(IV) chain isoform X1 [KO:K06237]
112948015  CSRP3; cysteine and glycine-rich protein 3 [KO:K09377]
112948145  PKP2; plakophilin-2 [KO:K12642]
112948293  ITGA11; integrin alpha-11 [KO:K06587]
112948918  TMOD1; tropomodulin-1 isoform X1 [KO:K10370]
112948995  COL1A1; collagen alpha-1(I) chain [KO:K06236]
112949032  ITGA3; integrin alpha-3 [KO:K06482]
112949034  SGCA; alpha-sarcoglycan [KO:K12565]
112949142  DAG1; dystroglycan [KO:K06265]
112949339  MYH15; myosin-15 [KO:K24220]
112949409  MYL2; LOW QUALITY PROTEIN: myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351]
112949503  MYH7B; myosin-7B [KO:K24220]
112949704  TNNC2; troponin C, skeletal muscle [KO:K12042]
112949758  SNTA1; alpha-1-syntrophin [KO:K24063]
112949773  SDC4; syndecan-4 isoform X1 [KO:K16338]
112949807  COL9A3; collagen alpha-3(IX) chain [KO:K08131]
112949813  PDLIM2; PDZ and LIM domain protein 2 [KO:K23353]
112949841  DES; desmin [KO:K07610]
112950211  MYPN; myopalladin [KO:K22028]
112950272  [KO:K12315]
112950310  FMNL3; formin-like protein 3 [KO:K23957]
112950315  ITGA5; integrin alpha-5 [KO:K06484]
112950446  ANK3; ankyrin-3 isoform X1 [KO:K09259]
112950534  LDB3; LIM domain-binding protein 3 isoform X1 [KO:K19867]
112950612  TPM3; tropomyosin alpha-3 chain isoform X1 [KO:K09290]
112950662  SSPN; LOW QUALITY PROTEIN: sarcospan [KO:K22194]
112950684  FMN2; formin-2 [KO:K02184]
112950719  FHL3; four and a half LIM domains protein 3 [KO:K24414]
112950757  SDC3; syndecan-3 [KO:K16337]
112950764  MYOM3; myomesin-3 [KO:K24495]
112950792  ITGA6; integrin alpha-6 isoform X1 [KO:K06485]
112950858  [KO:K08131]
112950899  TRIM63; E3 ubiquitin-protein ligase TRIM63 [KO:K10655] [EC:2.3.2.27]
112950999  [KO:K05692]
112951072  ITGA2B; integrin alpha-IIb [KO:K06476]
112951076  FMNL1; formin-like protein 1 [KO:K23957]
112951096  COL1A2; collagen alpha-2(I) chain [KO:K06236]
112951099  SGCE; epsilon-sarcoglycan isoform X1 [KO:K27061]
112951214  COL11A1; collagen alpha-1(XI) chain isoform X1 [KO:K19721]
112951477  VCL; vinculin isoform X1 [KO:K05700]
112951486  AMPD1; AMP deaminase 1 isoform X1 [KO:K01490] [EC:3.5.4.6]
112951653  SYNE1; nesprin-1 [KO:K19326]
112951687  ATP1B1; sodium/potassium-transporting ATPase subunit beta-1 [KO:K01540]
112951709  ZYX; zyxin isoform X1 [KO:K06273]
112951731  [KO:K05740]
112951817  PDLIM1; PDZ and LIM domain protein 1 [KO:K23353]
112951844  JUP; junction plakoglobin [KO:K10056]
112951887  MYOZ1; myozenin-1 [KO:K26050]
112952012  DSP; desmoplakin isoform X1 [KO:K10381]
112952049  THBS2; thrombospondin-2 [KO:K04659]
112952077  ITGB8; integrin beta-8 [KO:K06591]
112952120  SDC1; syndecan-1 [KO:K06257]
112952182  TLN1; talin-1 [KO:K06271]
112952184  TPM2; tropomyosin beta chain isoform X1 [KO:K09290]
112952455  PDLIM4; PDZ and LIM domain protein 4 [KO:K23353]
112952646  COL6A6; collagen alpha-6(VI) chain [KO:K06238]
112952765  [KO:K07611]
112952771  FBN1; fibrillin-1 [KO:K06825]
112952786  [KO:K10370]
112952798  TMOD3; tropomodulin-3 isoform X1 [KO:K10370]
112952960  THBS3; thrombospondin-3 [KO:K04659]
112953043  TNNC1; troponin C, slow skeletal and cardiac muscles [KO:K05865]
112953088  FBLN2; fibulin-2 [KO:K17307]
112953166  OBSCN; obscurin [KO:K17531] [EC:2.7.11.1]
112953494  FBN2; fibrillin-2 isoform X1 [KO:K23342]
112953524  LMNB1; lamin-B1 [KO:K07611]
112953558  TMOD4; tropomodulin-4 [KO:K10370]
112953568  ITGA10; LOW QUALITY PROTEIN: integrin alpha-10 [KO:K06586]
112953582  LMNA; LOW QUALITY PROTEIN: lamin [KO:K12641]
112953606  SYNE3; nesprin-3 [KO:K21761]
112953665  ITGB4; integrin beta-4 [KO:K06525]
112953876  [KO:K24220]
112953879  [KO:K24220]
112954227  ITGA7; integrin alpha-7 [KO:K06583]
112954387  MYOT; myotilin [KO:K19875]
112954395  PDLIM7; PDZ and LIM domain protein 7 isoform X1 [KO:K19867]
112954399  MYOZ3; myozenin-3 [KO:K26050]
112954467  COL6A3; collagen alpha-3(VI) chain [KO:K06238]
112954478  SGCD; delta-sarcoglycan [KO:K12563]
112954779  FN1; fibronectin [KO:K05717]
112954981  [KO:K19721]
112955223  [KO:K01539] [EC:7.2.2.13]
112955311  [KO:K24220]
112955313  [KO:K24220]
112955315  [KO:K24220]
112955349  [KO:K23958]
112955423  COL6A2; collagen alpha-2(VI) chain isoform X1 [KO:K06238]
112955443  ITGB1; integrin beta-1 isoform X1 [KO:K05719]
112955451  MYL1; myosin light chain 1/3, skeletal muscle isoform isoform X1 [KO:K05738]
112955490  SPTBN4; spectrin beta chain, non-erythrocytic 4 [KO:K06115]
112955772  [KO:K10653]
112955809  COL5A1; collagen alpha-1(V) chain isoform X1 [KO:K19721]
112955873  COL27A1; collagen alpha-1(XXVII) chain [KO:K19721]
112955897  COL6A1; collagen alpha-1(VI) chain [KO:K06238]
112955950  SPTAN1; spectrin alpha chain, non-erythrocytic 1 isoform X1 [KO:K06114]
112956103  [KO:K17751]
112956163  DSC1; desmocollin-1 [KO:K07601]
112956182  DSG2; desmoglein-2 [KO:K07597]
112956261  [KO:K27382]
112956354  SGCG; gamma-sarcoglycan [KO:K12564]
112956527  SDC2; syndecan-2 [KO:K16336]
112956671  ELN; elastin [KO:K14211]
112956767  PLEC; plectin [KO:K10388]
112956869  ATP1A1; sodium/potassium-transporting ATPase subunit alpha-1 [KO:K01539] [EC:7.2.2.13]
112956902  FBLN1; fibulin-1 [KO:K17307]
112956923  MYBPC2; myosin-binding protein C, fast-type [KO:K12558]
112957021  NRAP; nebulin-related-anchoring protein [KO:K24421]
112957096  ANKRD2; ankyrin repeat domain-containing protein 2 [KO:K21434]
112957383  ENO1; alpha-enolase [KO:K01689] [EC:4.2.1.11]
112957438  AGRN; agrin [KO:K06254]
112957596  COL9A1; collagen alpha-1(IX) chain [KO:K08131]
112957643  ANKRD1; ankyrin repeat domain-containing protein 1 [KO:K21433]
112957656  [KO:K24220]
112957677  [KO:K24220]
112957687  CUNH10orf71; cardiac-enriched FHL2-interacting protein [KO:K28413]
112957701  MYH10; myosin-10 [KO:K10352]
112957758  NID2; nidogen-2 [KO:K06826]
112957852  DTNA; dystrobrevin alpha isoform X1 [KO:K26998]
112957924  LMOD2; leiomodin-2 [KO:K22030]
112957975  THBS1; thrombospondin-1 [KO:K16857]
112958082  ACTC1; actin, alpha cardiac muscle 1 [KO:K12314]
112958118  XIRP1; xin actin-binding repeat-containing protein 1 [KO:K27381]
112958242  TTN; titin [KO:K12567] [EC:2.7.11.1]
112958253  ITGA4; integrin alpha-4 [KO:K06483]
112958297  [KO:K23932]
112958321  NEB; nebulin [KO:K18267]
112958415  MYH9; myosin-9 [KO:K10352]
112958476  ITGA9; integrin alpha-9 [KO:K06585]
112958680  LMOD3; leiomodin-3 [KO:K22030]
112958761  TMEM43; transmembrane protein 43 isoform X1 [KO:K27488]
112958910  TLN2; talin-2 [KO:K06271]
112958981  TPM1; tropomyosin alpha-1 chain isoform X1 [KO:K10373]
112959110  LMOD1; LOW QUALITY PROTEIN: leiomodin-1 [KO:K22030]
112959112  MYBPH; myosin-binding protein H [KO:K24494]
112959210  CSRP1; cysteine and glycine-rich protein 1 [KO:K09377]
112959216  TNNT2; troponin T, cardiac muscle [KO:K12045]
112959227  TNNI1; troponin I, slow skeletal muscle [KO:K10371]
112959377  ACTA1; actin, alpha skeletal muscle [KO:K10354]
112959585  CAPZB; F-actin-capping protein subunit beta isoform X1 [KO:K10365]
112959672  SYNE2; nesprin-2 isoform X1 [KO:K19346]
112959699  DAAM1; disheveled-associated activator of morphogenesis 1 isoform X1 [KO:K04512]
112959836  ITGB6; integrin beta-6 [KO:K06589]
112959838  SUN1; SUN domain-containing protein 1 isoform X1 [KO:K19347]
112959853  MYH11; myosin-11 isoform X1 [KO:K10352]
112959944  ACTB; actin, cytoplasmic 1 [KO:K05692]
112960082  ENO2; gamma-enolase [KO:K01689] [EC:4.2.1.11]
112960176  ITGB5; integrin beta-5 isoform X1 [KO:K06588]
112960206  TCAP; telethonin [KO:K19879]
112960264  MYL4; myosin light chain 4 [KO:K12750]
112960286  ITGB3; integrin beta-3 [KO:K06493]
Reference
  Authors
Clark KA, McElhinny AS, Beckerle MC, Gregorio CC
  Title
Striated muscle cytoarchitecture: an intricate web of form and function.
  Journal
Annu Rev Cell Dev Biol 18:637-706 (2002)
DOI:10.1146/annurev.cellbio.18.012502.105840
Reference
  Authors
Mukund K, Subramaniam S
  Title
Skeletal muscle: A review of molecular structure and function, in health and disease.
  Journal
Wiley Interdiscip Rev Syst Biol Med 12:e1462 (2020)
DOI:10.1002/wsbm.1462
Reference
  Authors
Stroud MJ, Banerjee I, Veevers J, Chen J
  Title
Linker of nucleoskeleton and cytoskeleton complex proteins in cardiac structure, function, and disease.
  Journal
Circ Res 114:538-48 (2014)
DOI:10.1161/CIRCRESAHA.114.301236
Reference
  Authors
Henderson CA, Gomez CG, Novak SM, Mi-Mi L, Gregorio CC
  Title
Overview of the Muscle Cytoskeleton.
  Journal
Compr Physiol 7:891-944 (2017)
DOI:10.1002/cphy.c160033
Reference
  Authors
Csapo R, Gumpenberger M, Wessner B
  Title
Skeletal Muscle Extracellular Matrix - What Do We Know About Its Composition, Regulation, and Physiological Roles? A Narrative Review.
  Journal
Front Physiol 11:253 (2020)
DOI:10.3389/fphys.2020.00253
Reference
  Authors
Pinch M, Guth R, Samanta MP, Chaidez A, Unguez GA
  Title
The myogenic electric organ of Sternopygus macrurus: a non-contractile tissue with a skeletal muscle transcriptome.
  Journal
PeerJ 4:e1828 (2016)
DOI:10.7717/peerj.1828
Reference
  Authors
Sequeira V, Nijenkamp LL, Regan JA, van der Velden J
  Title
The physiological role of cardiac cytoskeleton and its alterations in heart failure.
  Journal
Biochim Biophys Acta 1838:700-22 (2014)
DOI:10.1016/j.bbamem.2013.07.011
Reference
  Authors
Zhang B, Powers JD, McCulloch AD, Chi NC
  Title
Nuclear mechanosignaling in striated muscle diseases.
  Journal
Front Physiol 14:1126111 (2023)
DOI:10.3389/fphys.2023.1126111
Reference
  Authors
Al-Amoudi A, Castano-Diez D, Devos DP, Russell RB, Johnson GT, Frangakis AS
  Title
The three-dimensional molecular structure of the desmosomal plaque.
  Journal
Proc Natl Acad Sci U S A 108:6480-5 (2011)
DOI:10.1073/pnas.1019469108
Reference
  Authors
Sikora M, Ermel UH, Seybold A, Kunz M, Calloni G, Reitz J, Vabulas RM, Hummer G, Frangakis AS
  Title
Desmosome architecture derived from molecular dynamics simulations and cryo-electron tomography.
  Journal
Proc Natl Acad Sci U S A 117:27132-27140 (2020)
DOI:10.1073/pnas.2004563117
Reference
  Authors
Xu XP, Kim E, Swift M, Smith JW, Volkmann N, Hanein D
  Title
Three-Dimensional Structures of Full-Length, Membrane-Embedded Human alpha(IIb)beta(3) Integrin Complexes.
  Journal
Biophys J 110:798-809 (2016)
DOI:10.1016/j.bpj.2016.01.016
Reference
  Authors
Wang W, Shi Z, Jiao S, Chen C, Wang H, Liu G, Wang Q, Zhao Y, Greene MI, Zhou Z
  Title
Structural insights into SUN-KASH complexes across the nuclear envelope.
  Journal
Cell Res 22:1440-52 (2012)
DOI:10.1038/cr.2012.126
Reference
  Authors
Sosa BA, Kutay U, Schwartz TU
  Title
Structural insights into LINC complexes.
  Journal
Curr Opin Struct Biol 23:285-91 (2013)
DOI:10.1016/j.sbi.2013.03.005
Reference
  Authors
Cruz VE, Esra Demircioglu F, Schwartz TU
  Title
Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes.
  Journal
J Mol Biol 432:6028-6041 (2020)
DOI:10.1016/j.jmb.2020.09.019
Reference
  Authors
Schuler SC, Liu Y, Dumontier S, Grandbois M, Le Moal E, Cornelison D, Bentzinger CF
  Title
Extracellular matrix: Brick and mortar in the skeletal muscle stem cell niche.
  Journal
Front Cell Dev Biol 10:1056523 (2022)
DOI:10.3389/fcell.2022.1056523
Reference
  Authors
Brull A, Morales Rodriguez B, Bonne G, Muchir A, Bertrand AT
  Title
The Pathogenesis and Therapies of Striated Muscle Laminopathies.
  Journal
Front Physiol 9:1533 (2018)
DOI:10.3389/fphys.2018.01533
Reference
  Authors
Storey EC, Fuller HR
  Title
Genotype-Phenotype Correlations in Human Diseases Caused by Mutations of LINC Complex-Associated Genes: A Systematic Review and Meta-Summary.
  Journal
Cells 11:cells11244065 (2022)
DOI:10.3390/cells11244065
Related
pathway
npd04512  ECM-receptor interaction
npd04814  Motor proteins
KO pathway
ko04820   

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