KEGG   PATHWAY: ccw04820
Entry
ccw04820                    Pathway                                
Name
Cytoskeleton in muscle cells - Corvus cornix (hooded crow)
Class
Cellular Processes; Cell motility
Pathway map
ccw04820  Cytoskeleton in muscle cells
ccw04820

Organism
Corvus cornix (hooded crow) [GN:ccw]
Gene
104689333  COL1A2; collagen alpha-2(I) chain isoform X1 [KO:K06236]
120411203  COL1A1; LOW QUALITY PROTEIN: collagen alpha-1(I) chain [KO:K06236]
104693726  COL3A1; collagen alpha-1(III) chain isoform X1 [KO:K19720]
104688491  COL5A1; collagen alpha-1(V) chain isoform X1 [KO:K19721]
104693727  COL5A2; collagen alpha-2(V) chain isoform X1 [KO:K19721]
104695387  COL11A1; collagen alpha-1(XI) chain isoform X1 [KO:K19721]
104688442  collagen alpha-1(I) chain-like isoform X1 [KO:K19721]
104695557  COL24A1; collagen alpha-1(XXIV) chain isoform X1 [KO:K19721]
104688252  collagen alpha-1(XXVII) chain B isoform X1 [KO:K19721]
104687648  COL9A3; collagen alpha-3(IX) chain [KO:K08131]
104693161  COL9A1; collagen alpha-1(IX) chain isoform X1 [KO:K08131]
104698440  DCN; decorin [KO:K04660]
104695838  VCAN; versican core protein isoform X1 [KO:K06793]
104695800  ELN; elastin [KO:K14211]
104694557  COL6A3; collagen alpha-3(VI) chain isoform X1 [KO:K06238]
104694583  COL6A2; collagen alpha-2(VI) chain isoform X1 [KO:K06238]
104694607  COL6A1; collagen alpha-1(VI) chain [KO:K06238]
104689285  COL6A6; collagen alpha-6(VI) chain [KO:K06238]
104684025  THBS1; thrombospondin-1 [KO:K16857]
104695692  THBS4; thrombospondin-4 [KO:K04659]
104697387  LOW QUALITY PROTEIN: cartilage oligomeric matrix protein [KO:K04659]
104684330  THBS2; thrombospondin-2 isoform X2 [KO:K04659]
104683993  FBN1; fibrillin-1 [KO:K06825]
104691974  FBN2; fibrillin-2 isoform X1 [KO:K23342]
104697407  LOW QUALITY PROTEIN: fibrillin-2 [KO:K23342]
104694452  COL4A5; collagen alpha-5(IV) chain isoform X2 [KO:K06237]
104693432  COL4A4; collagen alpha-4(IV) chain isoform X3 [KO:K06237]
104693493  COL4A3; collagen alpha-3(IV) chain isoform X1 [KO:K06237]
104686327  COL4A1; collagen alpha-1(IV) chain [KO:K06237]
104694483  COL4A6; collagen alpha-6(IV) chain isoform X1 [KO:K06237]
104686326  COL4A2; collagen alpha-2(IV) chain [KO:K06237]
104695761  FBLN2; fibulin-2 [KO:K17307]
104696089  FBLN1; fibulin-1 isoform X1 [KO:K17307]
104698588  HSPG2; LOW QUALITY PROTEIN: basement membrane-specific heparan sulfate proteoglycan core protein [KO:K06255]
104684441  NID1; LOW QUALITY PROTEIN: nidogen-1 [KO:K06826]
104695902  NID2; LOW QUALITY PROTEIN: nidogen-2 [KO:K06826]
104694587  FN1; LOW QUALITY PROTEIN: fibronectin [KO:K05717]
104685497  SDC1; syndecan-1 [KO:K06257]
104692894  SDC2; syndecan-2 [KO:K16336]
104697719  SDC3; syndecan-3 [KO:K16337]
104687761  SDC4; syndecan-4 isoform X1 [KO:K16338]
104693404  AGRN; agrin isoform X1 [KO:K06254]
104690437  DSG2; desmoglein-2 [KO:K07597]
104696204  PKP2; plakophilin-2 isoform X1 [KO:K12642]
104697751  junction plakoglobin [KO:K10056]
104691380  desmoplakin isoform X1 [KO:K10381]
104689349  VIM; vimentin [KO:K07606]
104694186  DES; desmin [KO:K07610]
104687288  LAMA1; laminin subunit alpha-1 [KO:K05637]
104690723  LAMA2; laminin subunit alpha-2 isoform X1 [KO:K05637]
104686656  integrin alpha-1 [KO:K06480]
104686657  ITGA2; integrin alpha-2 isoform X1 [KO:K06481]
109143276  ITGA2B; LOW QUALITY PROTEIN: integrin alpha-IIb [KO:K06476]
120411187  ITGA3; LOW QUALITY PROTEIN: integrin alpha-3 [KO:K06482]
104694156  ITGA4; integrin alpha-4 [KO:K06483]
104693875  ITGA6; integrin alpha-6 isoform X3 [KO:K06485]
104689346  ITGA8; integrin alpha-8 [KO:K06584]
104689248  ITGA9; LOW QUALITY PROTEIN: integrin alpha-9 [KO:K06585]
104683868  ITGA11; integrin alpha-11 isoform X1 [KO:K06587]
104693720  ITGAV; integrin alpha-V [KO:K06487]
104686529  ITGB1; integrin beta-1 isoform X1 [KO:K05719]
104698490  ITGB3; integrin beta-3 isoform X1 [KO:K06493]
104694382  ITGB4; integrin beta-4 isoform X1 [KO:K06525]
104694025  ITGB5; integrin beta-5 [KO:K06588]
104693933  ITGB6; integrin beta-6 isoform X1 [KO:K06589]
104689120  ITGB8; LOW QUALITY PROTEIN: integrin beta-8 [KO:K06591]
104686746  TLN1; talin-1 isoform X1 [KO:K06271]
104683798  TLN2; LOW QUALITY PROTEIN: talin-2 [KO:K06271]
104697492  VCL; vinculin isoform X1 [KO:K05700]
104684280  ACTN2; alpha-actinin-2 isoform X2 [KO:K21073]
104684799  ACTB; actin, cytoplasmic 1 [KO:K05692]
120410965  ACTG1; LOW QUALITY PROTEIN: actin, cytoplasmic 2 [KO:K05692]
104683753  ACTG2; actin, gamma-enteric smooth muscle [KO:K12315]
104683200  DAG1; dystroglycan [KO:K06265]
120411223  SGCA; LOW QUALITY PROTEIN: alpha-sarcoglycan [KO:K12565]
104689164  SGCE; epsilon-sarcoglycan isoform X3 [KO:K27061]
104690640  SGCB; beta-sarcoglycan [KO:K12566]
104689550  SGCD; delta-sarcoglycan isoform X1 [KO:K12563]
104690017  SGCG; gamma-sarcoglycan [KO:K12564]
104690611  SGCZ; zeta-sarcoglycan isoform X1 [KO:K27062]
104696158  SSPN; sarcospan isoform X1 [KO:K22194]
104686213  DMD; dystrophin isoform X4 [KO:K10366]
104687900  SNTA1; alpha-1-syntrophin [KO:K24063]
104691947  SNTB2; beta-2-syntrophin [KO:K24064]
104692869  SNTB1; beta-1-syntrophin [KO:K24064]
104690408  DTNA; dystrobrevin alpha isoform X2 [KO:K26998]
120411918  FLNC; LOW QUALITY PROTEIN: filamin-C [KO:K27393]
104687046  ATP1A1; sodium/potassium-transporting ATPase subunit alpha-1 [KO:K01539] [EC:7.2.2.13]
104687204  ATP1B1; sodium/potassium-transporting ATPase subunit beta-1 [KO:K01540]
104693497  ATP1B3; sodium/potassium-transporting ATPase subunit beta-3 [KO:K01540]
104694435  ATP1B4; protein ATP1B4 isoform X1 [KO:K01540]
104690174  ANK3; ankyrin-3 isoform X9 [KO:K09259]
104688274  SPTAN1; spectrin alpha chain, non-erythrocytic 1 isoform X1 [KO:K06114]
104698591  SPTBN5; spectrin beta chain, non-erythrocytic 5 [KO:K06115]
104691490  SPTBN1; spectrin beta chain, non-erythrocytic 1 isoform X1 [KO:K06115]
104692458  CSRP1; cysteine and glycine-rich protein 1 [KO:K09377]
104697677  CSRP3; cysteine and glycine-rich protein 3 [KO:K09377]
104698406  CSRP2; cysteine and glycine-rich protein 2 [KO:K09377]
104695638  myosin-3-like isoform X2 [KO:K24220]
104695635  myosin-1B [KO:K24220]
104687777  MYH7B; myosin-7B isoform X1 [KO:K24220]
104687006  MYH15; myosin-15 [KO:K24220]
104695633  myosin-13 [KO:K24220]
104687376  myosin heavy chain, skeletal muscle, adult [KO:K24220]
104695679  myosin heavy chain, skeletal muscle, adult-like [KO:K24220]
104695682  myosin-1B-like isoform X1 [KO:K24220]
120410960  LOW QUALITY PROTEIN: myosin heavy chain, skeletal muscle, adult-like [KO:K24220]
104685921  LOW QUALITY PROTEIN: myosin-6-like [KO:K17751]
104685869  myosin-7 [KO:K17751]
104684897  MYH11; myosin-11 isoform X1 [KO:K10352]
104695627  MYH10; myosin-10 isoform X1 [KO:K10352]
104696276  MYH9; myosin-9 [KO:K10352]
104694537  MYL1; myosin light chain 1/3, skeletal muscle isoform isoform X1 [KO:K05738]
104686379  MYL3; myosin light chain 3 [KO:K12749]
104698635  myosin light chain, embryonic [KO:K12750]
104688679  MYL2; LOW QUALITY PROTEIN: myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351]
104698028  MYL9; myosin regulatory light polypeptide 9 [KO:K12755]
104696221  MYBPC1; myosin-binding protein C, slow-type isoform X1 [KO:K12557]
104697853  MYBPC3; myosin-binding protein C, cardiac-type isoform X1 [KO:K12568]
104692577  MYBPH; myosin-binding protein H [KO:K24494]
104684304  ACTA1; actin, alpha skeletal muscle [KO:K10354]
104684380  ACTC1; actin, alpha cardiac muscle 1 [KO:K12314]
104683235  TNNC1; troponin C, slow skeletal and cardiac muscles [KO:K05865]
104692460  TNNI1; troponin I, slow skeletal muscle isoform X3 [KO:K10371]
104687725  TNNC2; troponin C, skeletal muscle isoform X1 [KO:K12042]
104687956  TNNI2; troponin I, fast skeletal muscle [KO:K12043]
104687970  TNNT3; troponin T, fast skeletal muscle isoform X1 [KO:K12046]
104692574  TNNT2; troponin T, cardiac muscle isoform X1 [KO:K12045]
104683797  TPM1; tropomyosin alpha-1 chain isoform X1 [KO:K10373]
104686583  TPM2; tropomyosin beta chain isoform X3 [KO:K10374]
104697355  TPM4; tropomyosin alpha-4 chain isoform X2 [KO:K10375]
104694159  TTN; titin isoform X1 [KO:K12567] [EC:2.7.11.1]
109145671  muscle M-line assembly protein unc-89-like [KO:K12567] [EC:2.7.11.1]
104689607  MYOT; myotilin isoform X1 [KO:K19875]
120411369  telethonin [KO:K19879]
104693670  SYNPO2; synaptopodin-2 [KO:K24066]
104694229  NEB; LOW QUALITY PROTEIN: nebulin [KO:K18267]
104689223  NEBL; nebulette isoform X1 [KO:K25865]
104697375  MYOZ1; myozenin-1 isoform X2 [KO:K26050]
104693669  MYOZ2; myozenin-2 isoform X1 [KO:K26050]
104689571  MYOZ3; myozenin-3 [KO:K26050]
104690584  PDLIM3; PDZ and LIM domain protein 3 isoform X1 [KO:K23353]
104697116  PDLIM1; PDZ and LIM domain protein 1 isoform X4 [KO:K23353]
104697983  PDLIM4; PDZ and LIM domain protein 4 [KO:K23353]
120411140  PDLIM2; PDZ and LIM domain protein 2 isoform X1 [KO:K23353]
104698289  CAPZA2; F-actin-capping protein subunit alpha-2 isoform X2 [KO:K10364]
104692492  CAPZA1; F-actin-capping protein subunit alpha-1 [KO:K10364]
104697565  CAPZB; F-actin-capping protein subunit beta isoform X1 [KO:K10365]
104686417  XIRP1; xin actin-binding repeat-containing protein 1 isoform X1 [KO:K27381]
104695204  nebulin-related-anchoring protein [KO:K24421]
104690157  MYPN; myopalladin [KO:K22028]
104690186  LDB3; LIM domain-binding protein 3 isoform X1 [KO:K19867]
104689663  PDLIM7; PDZ and LIM domain protein 7 isoform X1 [KO:K19867]
104697197  PDLIM5; PDZ and LIM domain protein 5 isoform X1 [KO:K19867]
104684013  TMOD2; tropomodulin-2 [KO:K10370]
104689784  TMOD1; tropomodulin-1 isoform X1 [KO:K10370]
104684014  tropomodulin-3 [KO:K10370]
104687143  ZYX; LOW QUALITY PROTEIN: zyxin [KO:K06273]
104691265  FHL1; four and a half LIM domains protein 1 isoform X3 [KO:K14365]
104686082  FHL2; four and a half LIM domains protein 2 [KO:K14380]
104686821  LMOD2; leiomodin-2 [KO:K22030]
104692581  LMOD1; leiomodin-1 [KO:K22030]
104683363  LMOD3; leiomodin-3 [KO:K22030]
104696370  ANKRD1; ankyrin repeat domain-containing protein 1 [KO:K21433]
104697899  ANKRD2; ankyrin repeat domain-containing protein 2 [KO:K21434]
104694230  FMNL2; LOW QUALITY PROTEIN: formin-like protein 2 [KO:K23957]
104698539  FMNL1; LOW QUALITY PROTEIN: formin-like protein 1 [KO:K23957]
104684430  DAAM2; disheveled-associated activator of morphogenesis 2 isoform X1 [KO:K04512]
104684549  DAAM1; LOW QUALITY PROTEIN: disheveled-associated activator of morphogenesis 1 [KO:K04512]
104691315  DIAPH2; protein diaphanous homolog 2 isoform X4 [KO:K05741]
104693133  DIAPH3; protein diaphanous homolog 3 isoform X1 [KO:K05745]
104689054  FMN2; formin-2 isoform X1 [KO:K02184]
104687299  MYOM1; myomesin-1 isoform X4 [KO:K24495]
104693644  MYOM2; myomesin-2 isoform X2 [KO:K24495]
104687131  ENO2; gamma-enolase [KO:K01689] [EC:4.2.1.11]
104693328  ENO1; alpha-enolase [KO:K01689] [EC:4.2.1.11]
104696843  ANK2; LOW QUALITY PROTEIN: ankyrin-2 [KO:K09255]
104684504  TRIM54; tripartite motif-containing protein 54 [KO:K10653]
104692842  TRIM55; tripartite motif-containing protein 55 isoform X1 [KO:K10654]
104684653  AMPD3; AMP deaminase 3 isoform X1 [KO:K01490] [EC:3.5.4.6]
104692564  AMPD2; AMP deaminase 2 isoform X1 [KO:K01490] [EC:3.5.4.6]
104692409  AMPD1; AMP deaminase 1 isoform X1 [KO:K01490] [EC:3.5.4.6]
104686500  OBSCN; obscurin [KO:K17531] [EC:2.7.11.1]
104698659  CAPN3; calpain-3 isoform X1 [KO:K08573] [EC:3.4.22.54]
120409674  PLEC; LOW QUALITY PROTEIN: plectin [KO:K10388]
104686276  SYNE3; nesprin-3 isoform X2 [KO:K21761]
104690097  SYNE1; LOW QUALITY PROTEIN: nesprin-1 [KO:K19326]
104687171  SYNE2; nesprin-2 isoform X1 [KO:K19346]
104684835  SUN1; SUN domain-containing protein 1 isoform X1 [KO:K19347]
104696523  SUN2; SUN domain-containing protein 2 isoform X1 [KO:K19347]
104683306  TMEM43; transmembrane protein 43 [KO:K27488]
104685563  LBR; delta(14)-sterol reductase LBR isoform X2 [KO:K19532] [EC:1.3.1.70]
104691982  LMNB1; lamin-B1 isoform X1 [KO:K07611]
104696929  LMNB2; lamin-B2 [KO:K07611]
104683962  lamin-L(III)-like isoform X1 [KO:K07611]
Reference
PMID:12142273
  Authors
Clark KA, McElhinny AS, Beckerle MC, Gregorio CC
  Title
Striated muscle cytoarchitecture: an intricate web of form and function.
  Journal
Annu Rev Cell Dev Biol 18:637-706 (2002)
DOI:10.1146/annurev.cellbio.18.012502.105840
Reference
PMID:31407867
  Authors
Mukund K, Subramaniam S
  Title
Skeletal muscle: A review of molecular structure and function, in health and disease.
  Journal
Wiley Interdiscip Rev Syst Biol Med 12:e1462 (2020)
DOI:10.1002/wsbm.1462
Reference
PMID:24481844
  Authors
Stroud MJ, Banerjee I, Veevers J, Chen J
  Title
Linker of nucleoskeleton and cytoskeleton complex proteins in cardiac structure, function, and disease.
  Journal
Circ Res 114:538-48 (2014)
DOI:10.1161/CIRCRESAHA.114.301236
Reference
PMID:28640448
  Authors
Henderson CA, Gomez CG, Novak SM, Mi-Mi L, Gregorio CC
  Title
Overview of the Muscle Cytoskeleton.
  Journal
Compr Physiol 7:891-944 (2017)
DOI:10.1002/cphy.c160033
Reference
PMID:32265741
  Authors
Csapo R, Gumpenberger M, Wessner B
  Title
Skeletal Muscle Extracellular Matrix - What Do We Know About Its Composition, Regulation, and Physiological Roles? A Narrative Review.
  Journal
Front Physiol 11:253 (2020)
DOI:10.3389/fphys.2020.00253
Reference
PMID:27114860
  Authors
Pinch M, Guth R, Samanta MP, Chaidez A, Unguez GA
  Title
The myogenic electric organ of Sternopygus macrurus: a non-contractile tissue with a skeletal muscle transcriptome.
  Journal
PeerJ 4:e1828 (2016)
DOI:10.7717/peerj.1828
Reference
PMID:23860255
  Authors
Sequeira V, Nijenkamp LL, Regan JA, van der Velden J
  Title
The physiological role of cardiac cytoskeleton and its alterations in heart failure.
  Journal
Biochim Biophys Acta 1838:700-22 (2014)
DOI:10.1016/j.bbamem.2013.07.011
Reference
PMID:36960155
  Authors
Zhang B, Powers JD, McCulloch AD, Chi NC
  Title
Nuclear mechanosignaling in striated muscle diseases.
  Journal
Front Physiol 14:1126111 (2023)
DOI:10.3389/fphys.2023.1126111
Reference
PMID:21464301
  Authors
Al-Amoudi A, Castano-Diez D, Devos DP, Russell RB, Johnson GT, Frangakis AS
  Title
The three-dimensional molecular structure of the desmosomal plaque.
  Journal
Proc Natl Acad Sci U S A 108:6480-5 (2011)
DOI:10.1073/pnas.1019469108
Reference
PMID:33067392
  Authors
Sikora M, Ermel UH, Seybold A, Kunz M, Calloni G, Reitz J, Vabulas RM, Hummer G, Frangakis AS
  Title
Desmosome architecture derived from molecular dynamics simulations and cryo-electron tomography.
  Journal
Proc Natl Acad Sci U S A 117:27132-27140 (2020)
DOI:10.1073/pnas.2004563117
Reference
PMID:26910421
  Authors
Xu XP, Kim E, Swift M, Smith JW, Volkmann N, Hanein D
  Title
Three-Dimensional Structures of Full-Length, Membrane-Embedded Human alpha(IIb)beta(3) Integrin Complexes.
  Journal
Biophys J 110:798-809 (2016)
DOI:10.1016/j.bpj.2016.01.016
Reference
PMID:22945352
  Authors
Wang W, Shi Z, Jiao S, Chen C, Wang H, Liu G, Wang Q, Zhao Y, Greene MI, Zhou Z
  Title
Structural insights into SUN-KASH complexes across the nuclear envelope.
  Journal
Cell Res 22:1440-52 (2012)
DOI:10.1038/cr.2012.126
Reference
PMID:23597672
  Authors
Sosa BA, Kutay U, Schwartz TU
  Title
Structural insights into LINC complexes.
  Journal
Curr Opin Struct Biol 23:285-91 (2013)
DOI:10.1016/j.sbi.2013.03.005
Reference
PMID:33058875
  Authors
Cruz VE, Esra Demircioglu F, Schwartz TU
  Title
Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes.
  Journal
J Mol Biol 432:6028-6041 (2020)
DOI:10.1016/j.jmb.2020.09.019
Reference
PMID:36523505
  Authors
Schuler SC, Liu Y, Dumontier S, Grandbois M, Le Moal E, Cornelison D, Bentzinger CF
  Title
Extracellular matrix: Brick and mortar in the skeletal muscle stem cell niche.
  Journal
Front Cell Dev Biol 10:1056523 (2022)
DOI:10.3389/fcell.2022.1056523
Reference
PMID:30425656
  Authors
Brull A, Morales Rodriguez B, Bonne G, Muchir A, Bertrand AT
  Title
The Pathogenesis and Therapies of Striated Muscle Laminopathies.
  Journal
Front Physiol 9:1533 (2018)
DOI:10.3389/fphys.2018.01533
Reference
PMID:36552829
  Authors
Storey EC, Fuller HR
  Title
Genotype-Phenotype Correlations in Human Diseases Caused by Mutations of LINC Complex-Associated Genes: A Systematic Review and Meta-Summary.
  Journal
Cells 11:cells11244065 (2022)
DOI:10.3390/cells11244065
Related
pathway
ccw04512  ECM-receptor interaction
ccw04814  Motor proteins
KO pathway
ko04820   
LinkDB

DBGET integrated database retrieval system