Entry
Name
Spliceosome - Jatropha curcas (Barbados nut)
Description
After transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, the spliceosome. The standard spliceosome is made up of five small nuclear ribonucleoproteins (snRNPs), U1, U2, U4, U5, and U6 snRNPs, and several spliceosome-associated proteins (SAPs). Spliceosomes are not a simple stable complex, but a dynamic family of particles that assemble on the mRNA precursor and help fold it into a conformation that allows transesterification to proceed. Various spliceosome forms (e.g. A-, B- and C-complexes) have been identified.
Class
Genetic Information Processing; Transcription
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Jatropha curcas (Barbados nut) [GN:
jcu ]
Gene
105641019 LOW QUALITY PROTEIN: pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH7 [KO:K12815 ] [EC:5.6.2.6 ]
105629272 probable pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH5 isoform X1 [KO:K12818 ] [EC:5.6.2.6 ]
105629126 probable pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH2 isoform X1 [KO:K12820 ] [EC:5.6.2.6 ]
105636798 small nuclear ribonucleoprotein-associated protein B' [KO:K11086 ]
110010431 probable small nuclear ribonucleoprotein Sm D2 isoform X1 [KO:K11096 ]
105639549 transcription initiation factor TFIID subunit 15b isoform X1 [KO:K13098 ]
105636858 DNA-damage-repair/toleration protein DRT111, chloroplastic isoform X1 [KO:K12840 ]
105645054 U4/U6 small nuclear ribonucleoprotein PRP4-like protein [KO:K12662 ]
105635579 U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein [KO:K12846 ]
105629667 stromal 70 kDa heat shock-related protein, chloroplastic [KO:K03283 ]
105640140 stromal 70 kDa heat shock-related protein, chloroplastic isoform X1 [KO:K03283 ]
105647756 LOW QUALITY PROTEIN: heat shock cognate 70 kDa protein 2 [KO:K03283 ]
105647772 LOW QUALITY PROTEIN: heat shock cognate 70 kDa protein [KO:K03283 ]
105627963 apoptotic chromatin condensation inducer in the nucleus [KO:K12875 ]
105642133 serine/arginine-rich splicing factor RS2Z33 isoform X1 [KO:K12896 ]
105644565 serine/arginine-rich splicing factor RSZ21 isoform X1 [KO:K12896 ]
105628513 serine/arginine-rich splicing factor SR45a isoform X2 [KO:K12897 ]
Reference
Authors
Wahl MC, Will CL, Luhrmann R
Title
The spliceosome: design principles of a dynamic RNP machine.
Journal
Reference
Authors
Morris DP, Greenleaf AL
Title
The splicing factor, Prp40, binds the phosphorylated carboxyl-terminal domain of RNA polymerase II.
Journal
Reference
Authors
Chen YI, Moore RE, Ge HY, Young MK, Lee TD, Stevens SW
Title
Proteomic analysis of in vivo-assembled pre-mRNA splicing complexes expands the catalog of participating factors.
Journal
Reference
Authors
Ritchie DB, Schellenberg MJ, MacMillan AM
Title
Spliceosome structure: piece by piece.
Journal
KO pathway
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