KEGG   PATHWAY: cery04140
Entry
cery04140                   Pathway                                
Name
Autophagy - animal - Chanodichthys erythropterus (predatory carp)
Description
Autophagy (or macroautophagy) is a cellular catabolic pathway involving in protein degradation, organelle turnover, and non-selective breakdown of cytoplasmic components, which is evolutionarily conserved among eukaryotes and exquisitely regulated. This progress initiates with production of the autophagosome, a double-membrane intracellular structure of reticular origin that engulfs cytoplasmic contents and ultimately fuses with lysosomes for cargo degradation. Autophagy is regulated in response to extra- or intracellular stress and signals such as starvation, growth factor deprivation and ER stress. Constitutive level of autophagy plays an important role in cellular homeostasis and maintains quality control of essential cellular components.
Class
Cellular Processes; Transport and catabolism
Pathway map
cery04140  Autophagy - animal
cery04140

Other DBs
GO: 0006914
Organism
Chanodichthys erythropterus (predatory carp) [GN:cery]
Gene
137002612  uba52; ubiquitin-60S ribosomal protein L40 [KO:K02927]
137002728  bcl2b; apoptosis regulator Bcl-2 isoform X1 [KO:K02161]
137002819  prkacbb; protein kinase, cAMP-dependent, catalytic, beta b [KO:K04345] [EC:2.7.11.11]
137002848  rab8a; ras-related protein Rab-8A [KO:K07901]
137002995  map2k2b; dual specificity mitogen-activated protein kinase kinase 2b [KO:K04369] [EC:2.7.12.2]
137003082  dapk3; death-associated protein kinase 3 [KO:K08803] [EC:2.7.11.1]
137003113  pik3r2; phosphatidylinositol 3-kinase regulatory subunit beta isoform X1 [KO:K02649]
137003405  sh3glb1b; endophilin-B1b isoform X1 [KO:K11248]
137003474  gorasp1a; Golgi reassembly-stacking protein 1a [KO:K26797]
137003498  stk11; serine/threonine-protein kinase STK11 [KO:K07298] [EC:2.7.11.1]
137004124  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
137004293  ulk2; serine/threonine-protein kinase ULK2 isoform X1 [KO:K08269] [EC:2.7.11.1]
137004408  hif1al; hypoxia inducible factor 1 subunit alpha, like isoform X1 [KO:K08268]
137004493  hmgb1b; high mobility group protein B1b [KO:K10802]
137004504  [KO:K04526]
137004535  [KO:K20868]
137004549  vmp1; vacuole membrane protein 1 [KO:K21248]
137004581  atg16l1; autophagy-related protein 16-1 isoform X1 [KO:K17890]
137004952  si:ch211-11n16.2; zinc finger FYVE domain-containing protein 1 [KO:K17603]
137004988  rps6kb1b; ribosomal protein S6 kinase beta-1 [KO:K04688] [EC:2.7.11.1]
137005426  irs1; insulin receptor substrate 1-B isoform X1 [KO:K16172]
137006138  ptena; phosphatase and tensin homolog A isoform X1 [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
137006148  eif2ak4; eIF-2-alpha kinase GCN2 isoform X1 [KO:K16196] [EC:2.7.11.1]
137006156  atg2b; autophagy-related protein 2 homolog B isoform X1 [KO:K17906]
137006322  vps39; vam6/Vps39-like protein [KO:K20183]
137006342  ctsba; cathepsin B isoform X1 [KO:K01363] [EC:3.4.22.1]
137006397  birc6; baculoviral IAP repeat-containing protein 6 isoform X1 [KO:K10586] [EC:2.3.2.23]
137006461  akt1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
137006533  bnip4; BCL2 interacting protein 4 [KO:K15464]
137006542  eif2s1a; eukaryotic translation initiation factor 2 subunit 1a [KO:K03237]
137006567  nrbf2a; nuclear receptor binding factor 2a isoform X1 [KO:K21246]
137006933  atg14; beclin 1-associated autophagy-related key regulator [KO:K17889]
137007028  rragd; ras-related GTP-binding protein D [KO:K16186]
137007184  ctsl.1; cathepsin L.1 isoform X1 [KO:K01365] [EC:3.4.22.15]
137007498  [KO:K17908]
137007577  nrbf2b; nuclear receptor-binding factor 2b isoform X1 [KO:K21246]
137007660  ddit4; DNA damage-inducible transcript 4 protein [KO:K08270]
137007662  ptenb; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1 [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
137007804  becn1; beclin-1 isoform X1 [KO:K08334]
137007923  mlst8; target of rapamycin complex subunit lst8 [KO:K08266]
137007979  calcoco2; calcium-binding and coiled-coil domain-containing protein 2 [KO:K21348]
137008163  plekhm1; pleckstrin homology domain-containing family M member 1 isoform X1 [KO:K23282]
137008206  insb; LOW QUALITY PROTEIN: preproinsulin b [KO:K04526]
137008264  nbr1a; NBR1 autophagy cargo receptor a [KO:K17987]
137008268  mapk8b; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
137008270  bnip3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 [KO:K15464]
137008313  wdr45b; WD repeat domain phosphoinositide-interacting protein 3 [KO:K22991]
137008719  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
137009034  [KO:K08342] [EC:3.4.22.-]
137009164  [KO:K21247]
137009342  bcl2l1; bcl-2-like protein 1 [KO:K04570]
137009724  raf1a; raf-1 proto-oncogene, serine/threonine kinase a isoform X1 [KO:K04366] [EC:2.7.11.1]
137009787  zgc:158659; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
137010593  mtmr14; myotubularin-related protein 14 isoform X1 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
137010734  prkcda; protein kinase C, delta a [KO:K06068] [EC:2.7.11.13]
137010756  atg4b; cysteine protease ATG4B isoform X1 [KO:K08342] [EC:3.4.22.-]
137010769  atg4c; cysteine protease ATG4C isoform X1 [KO:K08342] [EC:3.4.22.-]
137010794  itpr1a; inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 [KO:K04958]
137010805  vps16; vacuolar protein sorting-associated protein 16 homolog [KO:K20180]
137010955  rhebl1; ras homolog, mTORC1 binding like 1 [KO:K07208]
137011362  atg9a; autophagy-related protein 9A isoform X1 [KO:K17907]
137011519  gorasp2; Golgi reassembly-stacking protein 2 [KO:K26797]
137011534  rps27a; ubiquitin-40S ribosomal protein S27a [KO:K02977]
137011544  atg3; ubiquitin-like-conjugating enzyme ATG3 [KO:K08343]
137011722  rptor; regulatory-associated protein of mTOR isoform X1 [KO:K07204]
137011727  pik3r3b; phosphoinositide-3-kinase, regulatory subunit 3b (gamma) isoform X1 [KO:K02649]
137012088  mapk9; mitogen-activated protein kinase 9 [KO:K04440] [EC:2.7.11.24]
137012171  mapk10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
137012503  atg4a; cysteine protease ATG4A isoform X1 [KO:K08342] [EC:3.4.22.-]
137012583  ulk1b; serine/threonine-protein kinase ULK1 isoform X1 [KO:K21357] [EC:2.7.11.1]
137012653  [KO:K07359] [EC:2.7.11.17]
137012850  bada; uncharacterized protein bada [KO:K02158]
137012855  wdr41; WD repeat-containing protein 41 isoform X1 [KO:K23610]
137012917  tsc1b; TSC complex subunit 1b isoform X1 [KO:K07206]
137013086  irs4a; insulin receptor substrate 2-B [KO:K07187]
137013247  ppp2cab; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform [KO:K04382] [EC:3.1.3.16]
137013344  rab39ba; RAB39B, member RAS oncogene family a [KO:K07925]
137013453  atg9b; autophagy-related protein 9B [KO:K17907]
137013533  rb1cc1; RB1-inducible coiled-coil protein 1 isoform X1 [KO:K17589]
137014046  bcl2a; apoptosis regulator Bcl-2a isoform X1 [KO:K02161]
137014047  sh3glb1a; endophilin-B1a isoform X1 [KO:K11248]
137014146  pdpk1b; 3-phosphoinositide-dependent protein kinase 1 isoform X1 [KO:K06276] [EC:2.7.11.1]
137014300  rheb; GTP-binding protein Rheb isoform X1 [KO:K07208]
137014358  vps41; vacuolar protein sorting-associated protein 41 homolog [KO:K20184]
137014378  gorasp1b; Golgi reassembly-stacking protein 1b [KO:K26797]
137014611  ambra1b; activating molecule in BECN1-regulated autophagy protein 1B [KO:K17985]
137014687  hrasa; HRas proto-oncogene, GTPase a isoform X1 [KO:K02833]
137015064  map1lc3b; microtubule-associated proteins 1A/1B light chain 3B [KO:K10435]
137015480  kras; GTPase KRas isoform X1 [KO:K07827]
137015530  gabarapl2; gamma-aminobutyric acid receptor-associated protein-like 2 [KO:K08341]
137015636  dapk2b; death-associated protein kinase 2 isoform X1 [KO:K08803] [EC:2.7.11.1]
137017306  prkacaa; protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a [KO:K04345] [EC:2.7.11.11]
137017371  napsa; napsin-A [KO:K01379] [EC:3.4.23.5]
137017475  zgc:55558; GTPase KRas [KO:K07827]
137017505  mapk3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
137017558  akt1s1; proline-rich AKT1 substrate 1 [KO:K16184]
137017621  rras; ras-related protein R-Ras [KO:K07830]
137017637  nbr1b; next to BRCA1 gene 1 protein isoform X1 [KO:K17987]
137017709  wipi1; WD repeat domain phosphoinositide-interacting protein 1 isoform X1 [KO:K17908]
137017768  smcr8a; guanine nucleotide exchange protein smcr8a [KO:K23611]
137017781  wipi2; WD repeat domain phosphoinositide-interacting protein 2 isoform X1 [KO:K17908]
137017817  pdpk1a; 3-phosphoinositide-dependent protein kinase 1a isoform X1 [KO:K06276] [EC:2.7.11.1]
137018005  ern1; serine/threonine-protein kinase/endoribonuclease IRE1 [KO:K08852] [EC:2.7.11.1 3.1.26.-]
137018406  vps18; vacuolar protein sorting-associated protein 18 homolog [KO:K20181]
137018646  ctsbb; cathepsin Bb [KO:K01363] [EC:3.4.22.1]
137018700  [KO:K04456] [EC:2.7.11.1]
137018853  hif1ab; hypoxia inducible factor 1 subunit alpha b [KO:K08268]
137018920  map3k7; mitogen-activated protein kinase kinase kinase 7 isoform X1 [KO:K04427] [EC:2.7.11.25]
137018994  zfyve1; zinc finger FYVE domain-containing protein 1 isoform X1 [KO:K17603]
137019002  atg2a; autophagy-related protein 2 homolog A isoform X1 [KO:K17906]
137019186  stx7l; syntaxin-7 [KO:K08488]
137019226  eif2s1b; eukaryotic translation initiation factor 2 subunit 1b [KO:K03237]
137019265  sqstm1; sequestosome-1 [KO:K14381]
137019395  prkaa2; 5'-AMP-activated protein kinase catalytic subunit alpha-2 isoform X1 [KO:K07198] [EC:2.7.11.31]
137019945  c9orf72; guanine nucleotide exchange factor C9orf72 homolog [KO:K23609]
137019950  eif2ak3; eukaryotic translation initiation factor 2-alpha kinase 3 [KO:K08860] [EC:2.7.11.1]
137020466  akt3a; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
137020537  rab1ab; ras-related protein Rab-1A [KO:K07874]
137020639  mapk8a; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
137020649  hif1aa; hypoxia inducible factor 1 subunit alpha a isoform X1 [KO:K08268]
137020837  [KO:K02977]
137020908  map1lc3c; microtubule-associated proteins 1A/1B light chain 3C [KO:K10435]
137021452  itpr1b; inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 isoform X1 [KO:K04958]
137021461  pik3ca; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
137021486  cflara; CASP8 and FADD-like apoptosis regulator a [KO:K04724]
137021521  map1lc3a; microtubule-associated proteins 1A/1B light chain 3A [KO:K10435]
137021537  si:dkey-13a21.4; ras-related protein Rab-7a isoform X1 [KO:K07897]
137021605  prkcdb; protein kinase C, delta b [KO:K06068] [EC:2.7.11.13]
137021623  rab7a; ras-related protein Rab-7a [KO:K07897]
137021706  prkacba; protein kinase, cAMP-dependent, catalytic, beta a [KO:K04345] [EC:2.7.11.11]
137021787  raf1b; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
137021796  map1lc3cl; microtubule-associated proteins 1A/1B light chain 3C [KO:K10435]
137021813  atg7; ubiquitin-like modifier-activating enzyme ATG7 [KO:K08337]
137021862  si:dkeyp-97e7.9; DEP domain-containing mTOR-interacting protein [KO:K20402]
137021982  rab33ba; RAB33B, member RAS oncogene family a [KO:K07920]
137022548  ppp2caa; protein phosphatase 2 catalytic subunit alpha a [KO:K04382] [EC:3.1.3.16]
137023110  akt2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
137023312  ctsd; cathepsin D [KO:K01379] [EC:3.4.23.5]
137023351  map2k1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
137023373  igf1ra; insulin-like growth factor 1a receptor isoform X1 [KO:K05087] [EC:2.7.10.1]
137023780  rraga; ras-related GTP-binding protein A [KO:K16185]
137024126  tbk1; serine/threonine-protein kinase TBK1 isoform X1 [KO:K05410] [EC:2.7.11.10]
137024246  atg5; autophagy protein 5 [KO:K08339]
137024270  optn; optineurin [KO:K19946]
137024583  prkcq; protein kinase C theta type [KO:K18052] [EC:2.7.11.13]
137025505  atg12; ubiquitin-like protein ATG12 [KO:K08336]
137026734  mtor; serine/threonine-protein kinase mTOR isoform X1 [KO:K07203] [EC:2.7.11.1]
137026787  snap29; synaptosomal-associated protein 29 [KO:K08509]
137026834  mtmr3; myotubularin-related protein 3 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
137026886  nras; GTPase NRas [KO:K07828]
137027126  stx17; syntaxin-17 [KO:K08491]
137027191  ulk1a; serine/threonine-protein kinase ULK1a [KO:K21357] [EC:2.7.11.1]
137027337  rab7b; ras-related protein Rab-7b [KO:K07897]
137027595  rubcn; run domain Beclin-1-interacting and cysteine-rich domain-containing protein isoform X1 [KO:K19330]
137027703  cts12; digestive cysteine proteinase 2 [KO:K01365] [EC:3.4.22.15]
137027832  mrasb; ras-related protein M-Ras [KO:K07831]
137028469  akt2l; v-akt murine thymoma viral oncogene homolog 2, like [KO:K04456] [EC:2.7.11.1]
137028509  ykt6; synaptobrevin homolog YKT6 [KO:K08516]
137028557  ubc; polyubiquitin-C [KO:K08770]
137028573  atg10; ubiquitin-like-conjugating enzyme ATG10 isoform X1 [KO:K17888]
137028645  hmgb1a; high mobility group protein B1a [KO:K10802]
137028665  supt20; transcription factor SPT20 homolog isoform X1 [KO:K21245]
137028719  rps6kb1a; ribosomal protein S6 kinase beta-1 [KO:K04688] [EC:2.7.11.1]
137028939  si:ch73-234b20.5; vesicle-associated membrane protein 8 [KO:K08512]
137028965  ppp2cb; serine/threonine-protein phosphatase 2A catalytic subunit beta isoform [KO:K04382] [EC:3.1.3.16]
137029156  map2k2a; dual specificity mitogen-activated protein kinase kinase 2a [KO:K04369] [EC:2.7.12.2]
137029446  wdr45; WD repeat domain phosphoinositide-interacting protein 4 [KO:K22991]
137029449  zgc:100918; ras-related protein rab7-like [KO:K07897]
137029609  atg101; autophagy-related protein 101 isoform X1 [KO:K19730]
137029613  uvrag; UV radiation resistance-associated gene protein [KO:K21249]
137029636  vps11; vacuolar protein sorting-associated protein 11 homolog [KO:K20179]
137029854  dapk2a; death-associated protein kinase 2a [KO:K08803] [EC:2.7.11.1]
137030054  gabarapb; GABA(A) receptor-associated protein b [KO:K08341]
137030221  [KO:K02158]
137030523  rras2; ras-related protein R-Ras2 isoform X1 [KO:K07830]
137030840  igf1rb; insulin-like growth factor 1b receptor isoform X1 [KO:K05087] [EC:2.7.10.1]
137030936  rab39bb; RAB39B, member RAS oncogene family b [KO:K07925]
137030982  pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X1 [KO:K00914] [EC:2.7.1.137]
137031178  [KO:K07187]
137031219  hrasb; HRas proto-oncogene, GTPase b [KO:K02833]
137031225  traf6; TNF receptor-associated factor 6 isoform X1 [KO:K03175] [EC:2.3.2.27]
137031301  tax1bp1b; tax1-binding protein 1 homolog B isoform X1 [KO:K21347]
137031308  ambra1a; activating molecule in BECN1-regulated autophagy protein 1A isoform X1 [KO:K17985]
137031311  atg13; autophagy-related protein 13 isoform X1 [KO:K08331]
137031447  [KO:K07920]
137031545  akt3b; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
137031596  deptor; DEP domain-containing mTOR-interacting protein isoform X1 [KO:K20402]
137031684  ern2; serine/threonine-protein kinase/endoribonuclease IRE1 [KO:K08852] [EC:2.7.11.1 3.1.26.-]
137031758  lamp1a; lysosome-associated membrane glycoprotein 1a [KO:K06528]
137031916  zgc:92606; gamma-aminobutyric acid receptor-associated protein-like 1 [KO:K08341]
137032045  irs2a; insulin receptor substrate 2a [KO:K07187]
137032077  rab1aa; RAB1A, member RAS oncogene family a [KO:K07874]
137032252  prkacab; cAMP-dependent protein kinase catalytic subunit alpha [KO:K04345] [EC:2.7.11.11]
137032873  smcr8b; guanine nucleotide exchange protein smcr8b [KO:K23611]
137033054  pik3r4; phosphoinositide 3-kinase regulatory subunit 4 isoform X1 [KO:K08333] [EC:2.7.11.1]
137033068  tsc2; tuberin isoform X1 [KO:K07207]
137033085  atg4da; cysteine protease atg4da isoform X1 [KO:K08342] [EC:3.4.22.-]
137033537  ubb; polyubiquitin-B [KO:K08770]
137033586  mapk1; mitogen-activated protein kinase 1 isoform X1 [KO:K04371] [EC:2.7.11.24]
137033684  mtmr4; myotubularin-related protein 4 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
137033704  epg5; ectopic P granules protein 5 homolog [KO:K23883]
137033709  rragca; ras-related GTP binding Ca [KO:K16186]
137033757  [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
137033766  dapk1; death-associated protein kinase 1 isoform X1 [KO:K08803] [EC:2.7.11.1]
137033876  tsc1a; TSC complex subunit 1a isoform X1 [KO:K07206]
137034072  zgc:73226; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 [KO:K15464]
137034156  prkaa1; 5'-AMP-activated protein kinase catalytic subunit alpha-1 [KO:K07198] [EC:2.7.11.31]
137034409  ins; insulin [KO:K04526]
137034719  vps33a; vacuolar protein sorting-associated protein 33A [KO:K20182]
137034733  igbp1; immunoglobulin-binding protein 1 [KO:K17606]
137034798  gabarapa; GABA(A) receptor-associated protein a [KO:K08341]
137034812  vamp8; vesicle-associated membrane protein 8 [KO:K08512]
137034923  wdfy3; WD repeat and FYVE domain-containing protein 3 isoform X1 [KO:K22262]
137035075  ctsla; cathepsin La [KO:K01365] [EC:3.4.22.15]
137035124  pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
137035132  ctsll; cathepsin L, like isoform X1 [KO:K01365] [EC:3.4.22.15]
137035719  mrasa; ras-related protein M-Ras isoform X1 [KO:K07831]
137035823  tank; TRAF family member-associated NF-kappa-B activator [KO:K12650]
137035843  zgc:101559; ras-related protein Rab-33B-like [KO:K07920]
137036313  lamp1b; lysosome-associated membrane glycoprotein 1b [KO:K06528]
137036317  [KO:K04724]
137036496  irs2b; insulin receptor substrate 2 [KO:K07187]
137037302  tax1bp1a; tax1-binding protein 1 homolog A [KO:K21347]
137037326  rragcb; ras-related GTP binding Cb isoform X1 [KO:K16186]
137037404  si:dkey-240h12.4; death-associated protein kinase 2 [KO:K08803] [EC:2.7.11.1]
Compound
C00035  GDP
C00044  GTP
C00350  Phosphatidylethanolamine
C01194  1-Phosphatidyl-D-myo-inositol
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
Reference
PMID:15325584
  Authors
Meijer AJ, Codogno P.
  Title
Regulation and role of autophagy in mammalian cells.
  Journal
Int J Biochem Cell Biol 36:2445-62 (2004)
DOI:10.1016/j.biocel.2004.02.002
Reference
PMID:16099218
  Authors
Deretic V.
  Title
Autophagy in innate and adaptive immunity.
  Journal
Trends Immunol 26:523-8 (2005)
DOI:10.1016/j.it.2005.08.003
Reference
PMID:16200202
  Authors
Levine B, Yuan J.
  Title
Autophagy in cell death: an innocent convict?
  Journal
J Clin Invest 115:2679-88 (2005)
DOI:10.1172/JCI26390
Reference
PMID:15325588
  Authors
Tanida I, Ueno T, Kominami E.
  Title
LC3 conjugation system in mammalian autophagy.
  Journal
Int J Biochem Cell Biol 36:2503-18 (2004)
DOI:10.1016/j.biocel.2004.05.009
Reference
PMID:15928708
  Authors
Lum JJ, DeBerardinis RJ, Thompson CB.
  Title
Autophagy in metazoans: cell survival in the land of plenty.
  Journal
Nat Rev Mol Cell Biol 6:439-48 (2005)
DOI:10.1038/nrm1660
Reference
PMID:15978794
  Authors
Reggiori F, Klionsky DJ.
  Title
Autophagosomes: biogenesis from scratch?
  Journal
Curr Opin Cell Biol 17:415-22 (2005)
DOI:10.1016/j.ceb.2005.06.007
Reference
PMID:11099404
  Authors
Klionsky DJ, Emr SD.
  Title
Autophagy as a regulated pathway of cellular degradation.
  Journal
Science 290:1717-21 (2000)
DOI:10.1126/science.290.5497.1717
Reference
PMID:16125113
  Authors
Bechet D, Tassa A, Taillandier D, Combaret L, Attaix D.
  Title
Lysosomal proteolysis in skeletal muscle.
  Journal
Int J Biochem Cell Biol 37:2098-114 (2005)
DOI:10.1016/j.biocel.2005.02.029
Reference
PMID:19653858
  Authors
He C, Klionsky DJ
  Title
Regulation mechanisms and signaling pathways of autophagy.
  Journal
Annu Rev Genet 43:67-93 (2009)
DOI:10.1146/annurev-genet-102808-114910
Reference
PMID:19802558
  Authors
Yang Z, Klionsky DJ
  Title
An overview of the molecular mechanism of autophagy.
  Journal
Curr Top Microbiol Immunol 335:1-32 (2009)
DOI:10.1007/978-3-642-00302-8_1
Reference
PMID:20034776
  Authors
Yang Z, Klionsky DJ
  Title
Mammalian autophagy: core molecular machinery and signaling regulation.
  Journal
Curr Opin Cell Biol 22:124-31 (2010)
DOI:10.1016/j.ceb.2009.11.014
Reference
PMID:21187343
  Authors
Chen Y, Klionsky DJ
  Title
The regulation of autophagy - unanswered questions.
  Journal
J Cell Sci 124:161-70 (2011)
DOI:10.1242/jcs.064576
Reference
PMID:21801009
  Authors
Mizushima N, Yoshimori T, Ohsumi Y
  Title
The role of Atg proteins in autophagosome formation.
  Journal
Annu Rev Cell Dev Biol 27:107-32 (2011)
DOI:10.1146/annurev-cellbio-092910-154005
Reference
PMID:24343578
  Authors
Russell RC, Yuan HX, Guan KL
  Title
Autophagy regulation by nutrient signaling.
  Journal
Cell Res 24:42-57 (2014)
DOI:10.1038/cr.2013.166
Reference
PMID:25948417
  Authors
Noda NN, Fujioka Y
  Title
Atg1 family kinases in autophagy initiation.
  Journal
Cell Mol Life Sci 72:3083-96 (2015)
DOI:10.1007/s00018-015-1917-z
Related
pathway
cery04010  MAPK signaling pathway
cery04141  Protein processing in endoplasmic reticulum
cery04142  Lysosome
cery04150  mTOR signaling pathway
cery04910  Insulin signaling pathway
KO pathway
ko04140   

DBGET integrated database retrieval system