KEGG ORTHOLOGY: K23282

ORTHOLOGY: K23282

Entry

K23282                      KO

Symbol

PLEKHM1

Name

pleckstrin homology domain-containing family M member 1

Pathway

map04140

Autophagy - animal

map05132

Salmonella infection

Disease

H00436

Osteopetrosis

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    K23282  PLEKHM1; pleckstrin homology domain-containing family M member 1
09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K23282  PLEKHM1; pleckstrin homology domain-containing family M member 1
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K23282  PLEKHM1; pleckstrin homology domain-containing family M member 1
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified
    K23282  PLEKHM1; pleckstrin homology domain-containing family M member 1
Membrane trafficking [BR:ko04131]
SNARE
  SNARE associated proteins
   Others
    K23282  PLEKHM1; pleckstrin homology domain-containing family M member 1
Domain-containing proteins not elsewhere classified [BR:ko04990]
Pleckstrin homology (PH) domain-containing proteins
  Other PH domain-containing proteins
   K23282  PLEKHM1; pleckstrin homology domain-containing family M member 1

Genes

HSA:	9842(PLEKHM1)

PTR:	454754(PLEKHM1)

PPS:	100985810(PLEKHM1)

GGO:	101135518 101151290 115934627(PLEKHM1)

PON:	100174604(PLEKHM1)

PPYG:

129017199(PLEKHM1)

NLE:	100600060(PLEKHM1)

HMH:	116474984(PLEKHM1)

SSYN:

129470223(PLEKHM1)

MCC:	716464(PLEKHM1)

MCF:	102147089(PLEKHM1)

MTHB:

126938918

MNI:	105468547(PLEKHM1)

CSAB:

103243285(PLEKHM1)

CATY:

105573052 105585620(PLEKHM1)

PANU:

101000352(PLEKHM1)

TGE:	112609444(PLEKHM1)

MLEU:

105543835(PLEKHM1)

RRO:	104678371(PLEKHM1)

RBB:

108522107

TFN:	117066849 117066850 117083944 117087918

PTEH:

111525823(PLEKHM1)

CANG:

105510395(PLEKHM1)

CJC:	100396533(PLEKHM1)

SBQ:	101046504(PLEKHM1)

CIMI:

108318322(PLEKHM1)

ANAN:

105711320(PLEKHM1)

CSYR:

103256214(PLEKHM1)

MMUR:

105883599(PLEKHM1)

LCAT:

123621035(PLEKHM1)

PCOQ:

105827252(PLEKHM1)

OGA:	100956570(PLEKHM1)

MMU:	353047(Plekhm1)

MCAL:

110304741(Plekhm1)

MPAH:

110331771(Plekhm1)

RNO:	303584(Plekhm1)

MCOC:

116076679(Plekhm1)

ANU:	117710921(Plekhm1)

ASYL:

127693383(Plekhm1)

MUN:	110545642(Plekhm1)

CGE:	100766166(Plekhm1)

MAUA:

101825397(Plekhm1)

PROB:

127216771(Plekhm1)

PLEU:

114702265(Plekhm1)

MORG:

121436169(Plekhm1)

MFOT:

126510255

AAMP:

119812913(Plekhm1)

NGI:	103724785 103738322(Plekhm1)

HGL:	101701904(Plekhm1)

CPOC:

100719025(Plekhm1)

CCAN:

109694420(Plekhm1)

DORD:

105997550(Plekhm1)

DSP:	122103336(Plekhm1)

DMER:

138830955(Plekhm1)

PLOP:

125365112(Plekhm1)

NCAR:

124980316

MMMA:

107150673(Plekhm1)

ITI:	101958777(Plekhm1)

OCU:

100338936

OPI:	101536213(PLEKHM1)

TUP:	102501428(PLEKHM1)

GVR:	103607128(PLEKHM1)

CFA:	119873243(PLEKHM1)

CLUD:

112670287(PLEKHM1)

VVP:	112912653 112912673(PLEKHM1)

NPO:	129514772(PLEKHM1)

AML:	100472762(PLEKHM1)

UMR:	103665605(PLEKHM1)

UAH:	113265318(PLEKHM1)

UAR:	123802907(PLEKHM1)

ELK:

111158078

LLV:

125087392

MPUF:

101686539(PLEKHM1)

MNP:	132003395(PLEKHM1)

MLK:	131816840(PLEKHM1)

NVS:	122906114(PLEKHM1)

ORO:	101381094(PLEKHM1)

EJU:	114200583(PLEKHM1)

ZCA:	113908029(PLEKHM1)

MLX:	118025162(PLEKHM1)

NSU:	110573257(PLEKHM1)

LWW:	102737582(PLEKHM1)

FCA:	101087796(PLEKHM1) 123378959

PBG:	122485717(PLEKHM1)

PVIV:

125158399(PLEKHM1)

LRUF:

124500911 124513567 124513568 124522172 124522173 124522176 124527892 124527901

LGF:	123603862(PLEKHM1)

AJU:

106988154

PTG:	102964959(PLEKHM1)

PPAD:

109258159(PLEKHM1)

PUC:

125927690

PLEZ:

122207321(PLEKHM1) 122212772

HHV:	120227153(PLEKHM1) 120237742

BTA:	523424(PLEKHM1)

BOM:	102270186(PLEKHM1)

BIU:	109574387(PLEKHM1)

BBUB:

102399032(PLEKHM1)

BBIS:

104982958(PLEKHM1)

CHX:	102168577(PLEKHM1)

OAS:	101119061(PLEKHM1)

BTAX:

128064907(PLEKHM1)

CSUM:

138083215(PLEKHM1)

ODA:	120866993(PLEKHM1)

CCAD:

122440198(PLEKHM1)

MREE:

136149263(PLEKHM1)

OVR:	110124757(PLEKHM1)

MBEZ:

129544512(PLEKHM1)

SSC:	100523462(PLEKHM1)

CFR:	102508146(PLEKHM1)

CBAI:

105072523(PLEKHM1)

CDK:	105094400(PLEKHM1)

VPC:	102544579(PLEKHM1)

BACU:

103014561(PLEKHM1)

BMUS:

118886298

LVE:	103083037(PLEKHM1)

OOR:	101269613(PLEKHM1)

LALB:

132510791(PLEKHM1)

GMF:	115848278(PLEKHM1)

DLE:	111170189(PLEKHM1)

PCAD:

102991825(PLEKHM1)

PSIU:

116746380(PLEKHM1)

PPHC:

136138765(PLEKHM1)

NASI:

112410225(PLEKHM1)

ECB:	100050008(PLEKHM1)

EPZ:	103554687(PLEKHM1)

EAI:	106836483(PLEKHM1)

MYB:	102263293(PLEKHM1)

MYD:	102763471(PLEKHM1)

MMYO:

118671353(PLEKHM1)

MLF:	102433119(PLEKHM1)

MDT:	132218769(PLEKHM1)

MYUM:

138994674(PLEKHM1)

PKL:	118726365(PLEKHM1)

EFUS:

103293008(PLEKHM1)

MNA:	107528875(PLEKHM1)

DRO:	112298610(PLEKHM1)

SHON:

119001593(PLEKHM1)

AJM:	119061557(PLEKHM1)

PDIC:

114503983(PLEKHM1)

PHAS:

123817088(PLEKHM1)

MMF:	118633875(PLEKHM1)

PPAM:

129086420(PLEKHM1)

HAI:	109394958(PLEKHM1)

RFQ:	117013244(PLEKHM1)

PALE:

102898419(PLEKHM1)

PGIG:

120589255(PLEKHM1)

PVP:	105303520(PLEKHM1)

RAY:	107508167(PLEKHM1)

MJV:	108396087(PLEKHM1)

TOD:	119233026(PLEKHM1)

SARA:

101554977(PLEKHM1)

SFUM:

130035511(PLEKHM1)

SETR:

126016487(PLEKHM1)

LAV:	100662214(PLEKHM1)

TMU:	101344607 101345528

ETF:	101652092(PLEKHM1)

DNM:

101428882

MDO:	100024491(PLEKHM1)

GAS:	123244032(PLEKHM1)

SHR:	100918641(PLEKHM1)

AFZ:

127560375

PCW:	110215731(PLEKHM1)

TVP:	118847685(PLEKHM1)

PBRV:

138152425(PLEKHM1)

OAA:	100076168(PLEKHM1)

TACU:

119934714(PLEKHM1)

GGA:	419939(PLEKHM1)

PCOC:

116233841(PLEKHM1)

MGP:	100539071(PLEKHM1)

CJO:	107325048(PLEKHM1)

TPAI:

128088792(PLEKHM1)

LMUT:

125684597(PLEKHM1)

NMEL:

110388468(PLEKHM1)

APLA:

101792908(PLEKHM1)

ACYG:

106046906(PLEKHM1)

CATA:

118258258(PLEKHM1)

AFUL:

116498608(PLEKHM1)

TGU:	100222386(PLEKHM1)

LSR:	110475636(PLEKHM1)

SCAN:

103821651(PLEKHM1)

PMOA:

120498284(PLEKHM1)

OTC:	121332972(PLEKHM1)

PRUF:

121350548(PLEKHM1)

ATRC:

139601608(PLEKHM1)

GFR:	102044156(PLEKHM1)

FAB:	101811486(PLEKHM1)

OMA:	130264071(PLEKHM1)

PHI:	102114756(PLEKHM1)

PMAJ:

107215299(PLEKHM1)

CCAE:

111940099(PLEKHM1)

CCW:	104698547(PLEKHM1)

CBRC:

103622676(PLEKHM1)

ACOE:

138099199(PLEKHM1)

ETL:	114071685(PLEKHM1)

ZAB:	102067761(PLEKHM1)

ZLE:	135458520(PLEKHM1)

ACHL:

103800781(PLEKHM1)

SVG:	106858276(PLEKHM1)

MMEA:

130586943(PLEKHM1)

HRT:	120763696(PLEKHM1)

SATI:

136372191(PLEKHM1)

CCIC:

134053201(PLEKHM1)

FPG:	101911931(PLEKHM1)

FCH:	102060135(PLEKHM1)

CCRI:

104160933(PLEKHM1)

NNT:	104412765(PLEKHM1)

SHAB:

115617899(PLEKHM1)

ACUN:

113489212(PLEKHM1)

TALA:

104363769(PLEKHM1)

ACHC:

115344280(PLEKHM1)

HALD:

104321033(PLEKHM1)

HLE:	104827961(PLEKHM1)

AGEN:

126038142

HHAR:

128140775(PLEKHM1)

GCL:

127026409

LDI:	104348758(PLEKHM1)

PPUS:

135191908(PLEKHM1)

AVIT:

104277062(PLEKHM1)

BRHI:

104494466(PLEKHM1)

EGZ:	104131082(PLEKHM1)

NNI:	104012275(PLEKHM1)

PCAO:

104042512(PLEKHM1)

PADL:

103926095(PLEKHM1)

AFOR:

103906045(PLEKHM1)

FGA:	104071318(PLEKHM1)

GSTE:

104261986

CBOY:

140662387(PLEKHM1)

CLV:

102083987

CNIC:

135997915(PLEKHM1)

MUI:

104546972

PLET:

104627237(PLEKHM1)

EHS:	104516183(PLEKHM1)

CMAC:

104485272(PLEKHM1)

CUCA:

104064887(PLEKHM1)

TEO:	104381207(PLEKHM1)

BREG:

104639099(PLEKHM1)

OHA:	104327977(PLEKHM1)

ACAR:

104525119(PLEKHM1)

CPEA:

104390225(PLEKHM1)

CVF:	104285392(PLEKHM1)

RTD:	128919216(PLEKHM1)

CRID:

134524365(PLEKHM1)

AAM:	106486449(PLEKHM1)

AROW:

112965765(PLEKHM1)

NPD:	112954209(PLEKHM1)

TGT:	104580371(PLEKHM1)

DNE:	112982800(PLEKHM1)

SCAM:

104150865(PLEKHM1)

ASN:	102370239(PLEKHM1)

AMJ:	102572484(PLEKHM1)

CPOO:

109323047(PLEKHM1)

GGN:	109302071(PLEKHM1)

PSS:	102460104(PLEKHM1)

CMY:	102938953(PLEKHM1)

CCAY:

125626908(PLEKHM1)

DCC:	119848954(PLEKHM1)

CPIC:

101939138(PLEKHM1)

TST:	117869202(PLEKHM1)

CABI:

116826957(PLEKHM1)

MRV:	120385059(PLEKHM1)

ACS:	100555476(plekhm1)

ASAO:

132778356(PLEKHM1)

PVT:	110090739(PLEKHM1)

SUND:

121934430(PLEKHM1)

PBI:	103057344(PLEKHM1)

PMUR:

107294563(PLEKHM1)

CTIG:

120298171 120298509(PLEKHM1) 120298901 120299057

TSR:	106544554 106555080

PGUT:

117664878(PLEKHM1)

APRI:

131196587(PLEKHM1)

PTEX:

113449822(PLEKHM1)

NSS:	113424416(PLEKHM1)

VKO:	123017371(PLEKHM1)

PMUA:

114581949(PLEKHM1)

PRAF:

128399708(PLEKHM1)

ZVI:	118095030(PLEKHM1)

HCG:

128330709

GJA:	107114952(PLEKHM1)

EMC:	129340050(PLEKHM1)

XLA:	108700887(plekhm1.L) 108702586(plekhm1.S)

XTR:	100491541(plekhm1)

NPR:	108803794(PLEKHM1)

RTEM:

120918944(PLEKHM1)

ACAT:

141113573(PLEKHM1)

BBUF:

121003113(PLEKHM1)

BGAR:

122940152(PLEKHM1)

DTC:	141094661(PLEKHM1)

PWL:	138299633(PLEKHM1)

MUO:	115481495(PLEKHM1)

GSH:	117347379(PLEKHM1)

DRE:	564048(plekhm1)

SRX:	107708944 107732179

SANH:

107654030 107664630

SGH:	107557367(plekhm1) 107598641

CCAR:

109073760 109099339

CAUA:

113056379 113111974

CGIB:

127969177 128025030

PTET:

122355649(plekhm1)

LROH:

127174110(plekhm1)

GRF:	141298200(plekhm1)

OMC:	131551423(plekhm1)

PPRM:

120474443(plekhm1)

RKG:	130080571(plekhm1)

MAMB:

125255088(plekhm1)

CIDE:

127523459

CERY:

137008163(plekhm1)

MASI:

127423249 127427378

TROS:

130569402(plekhm1)

TDW:	130438851(plekhm1)

MANU:

129420347(plekhm1)

PDAB:

135720537(plekhm1)

IPU:

108273964

IFU:	128617132(plekhm1)

PHYP:

113527479(plekhm1)

SMEO:

124388963(plekhm1)

TFD:	113653568(plekhm1)

TVC:	132841570(plekhm1)

CGAR:

128541353(plekhm1)

NGRA:

132898125(plekhm1)

TRN:	134321096(plekhm1)

AMEX:

103022451(plekhm1)

CMAO:

118809652(plekhm1)

EEE:	113588314(plekhm1)

CHAR:

105909509

SPIL:

134069735(plekhm1)

TRU:	101069796(plekhm1)

TFS:	130539780(plekhm1)

TNG:	GSTEN00026949G001

LCO:	104928473(plekhm1)

NCC:	104957046(plekhm1)

TBEN:

117473707(plekhm1)

CGOB:

115024928(plekhm1)

PGEO:

117464921(plekhm1)

GACU:

117547409(plekhm1)

EMAC:

134870890(plekhm1)

ELY:	117247105(plekhm1)

EFO:	125880749(plekhm1)

PLEP:

121958683(plekhm1)

SLUC:

116061496(plekhm1)

ECRA:

117936739(plekhm1)

ESP:	116670951(plekhm1)

PFLV:

114548173(plekhm1)

GAT:	120819347(plekhm1)

PPUG:

119212898(plekhm1)

AFB:	129091637(plekhm1)

CLUM:

117748505(plekhm1)

PSWI:

130203897(plekhm1)

CANA:

137790012(plekhm1)

MSAM:

119916219(plekhm1)

SCHU:

122867470(plekhm1)

CUD:	121528370(plekhm1)

SPUL:

138594015(plekhm1)

LMIX:

132955014(plekhm1)

ALAT:

119009237(plekhm1)

ASTR:

137588341(plekhm1)

MZE:	101486039(plekhm1)

ONL:	100704351(plekhm1)

OAU:	116324091(plekhm1)

OLA:	101171704(plekhm1)

OML:	112154473(plekhm1)

CSAI:

133419008(plekhm1)

XMA:	102219869(plekhm1)

XCO:	114152134(plekhm1)

XHE:	116727303(plekhm1)

PRET:

103481681(plekhm1)

PFOR:

103151707(plekhm1)

PLAI:

106964463(plekhm1)

PMEI:

106921396(plekhm1)

GAF:	122823474(plekhm1)

PPRL:

129368208(plekhm1)

CVG:	107093217(plekhm1)

CTUL:

119791075(plekhm1)

GMU:	124875519(plekhm1)

NFU:	107387647(plekhm1)

KMR:	108249893(plekhm1)

ALIM:

106535567(plekhm1)

NWH:	119423814(plekhm1)

AOCE:

111587458(plekhm1)

EJA:	138204719(plekhm1)

BFRE:

138624423(plekhm1)

MCEP:

125022701(plekhm1)

CSEM:

103381563(plekhm1)

POV:	109642112 109647671

SSEN:

122759561(plekhm1)

SSOE:

131448722(plekhm1)

HHIP:

117752523(plekhm1)

HSP:	118100588(plekhm1)

PPLT:

128426485(plekhm1)

SMAU:

118287386(plekhm1)

LCF:

108894802

SDU:	111220282(plekhm1)

SLAL:

111656152(plekhm1)

XGL:	120794582(plekhm1)

HCQ:	109513229(plekhm1)

SSCV:

125991079(plekhm1)

SBIA:

133495789(plekhm1)

PEE:	133418256(plekhm1)

PTAO:

133469707(plekhm1)

BPEC:

110154217(plekhm1)

ENY:	140369569(plekhm1)

MALB:

109969584(plekhm1)

BSPL:

114845987(plekhm1)

SJO:	128381916(plekhm1)

SSCO:

134003332(plekhm1)

GMH:	115531182(plekhm1)

SASA:

106578308 106579266

STRU:

115159131 115200953

OTW:	112223638 112224091

OMY:	110491541 110498830

OGO:	124039912 124048307

ONE:	115106515 115143925

OKI:	109865930 109870363

OKE:	118357607 118366405

OMM:	135504978 135523958

OCLA:

139368105 139376445

SALP:

111976344 111978041 112080578

SNH:	120046229 120060901

CCLU:

121547243 121568009

ELS:	105024516(plekhm1)

OEP:	134030949(plekhm1)

SFM:	108924849(plekhm1)

PKI:	111856793(plekhm1)

AANG:

118220930(plekhm1)

AROT:

135247843(plekhm1)

CCOG:

133122266(plekhm1)

LOC:	102693574(plekhm1)

PSPA:

121324149(plekhm1)

ARUT:

117435084(plekhm1)

PSEX:

120517113(plekhm1)

LCM:	102347592(PLEKHM1)

CMK:

103187723

RTP:	109920132(plekhm1)

CPLA:

122539997(plekhm1)

HOC:	132830965(plekhm1)

LERI:

129710403(plekhm1)

HAKA:

140741036(plekhm1)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

AJC:

SKO:

DME:	Dmel_CG6613(Plekhm1)

DER:

6548169

DSE:

6615479

DSI:	Dsimw501_GD11643(Dsim_GD11643)

DYA:	Dyak_GE12240

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI18818

DAZ:

108616617

DNV:

115564525

DHE:

111597025

DVI:	6627078(Plekhm1)

CCAT:

BOD:

BDR:

RZE:

AOQ:

ALUD:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

CVJ:	135962219(Plekhm1)

GFS:

ECOE:

CLON:

HIS:

CNS:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

MZT:	108728552(Plekhm1)

PBAR:

105429330

VEM:

105566454

COBS:

139107083(Plekhm1)

TLN:	139823750(Plekhm1)

HST:

DQU:

CFO:

FEX:

PMEC:

138932286(Plekhm1)

LHU:	105679108(Plekhm1)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

VCAN:

CCIN:

DSM:

NPT:	124219277(Plekhm1)

NFB:

NLO:

NVG:

AROA:

TCA:

TMOL:

138140393(Plekhm1)

DPA:

109540991

ESIM:

136410578(Plekhm1)

EFOR:

136350452(Plekhm1)

ATD:

HAXR:

DVV:

NVL:

BMOR:

MSEX:

DPL:	KGM_204272

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ONU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CSTB:

CFUM:

141429811(Plekhm1)

CFEL:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

BTAB:

DCI:

CLEC:

NLU:

MQU:

PHU:	Phum_PHUM397250

FOC:

TPAL:

ZNE:

CSEC:

PAME:

138707824(Plekhm1)

BROR:

134529052

IEL:

124170748

HAMR:

139689429(Plekhm1)

FCD:

110851223

DPX:	DAPPUDRAFT_57290

DMK:

116924961

DPZ:

124320992

AFRA:

136038097

PVM:	138860752(Plekhm1)

PJA:

PCHN:

PMOO:

HAME:

PCLA:

123761023(Plekhm1)

CQD:	128693971(Plekhm1)

PTRU:

123504051

ESN:

127004017

MNZ:

135209056

MRJ:	136830236(Plekhm1)

PORN:

139749485(Plekhm1)

HAZT:

EAF:

DSV:

RSAN:

RMP:

VDE:

VJA:

GOE:

TUT:

DPTE:

DFR:

CSCU:

CVS:	136975283(Plekhm1)

PTEP:

ABRU:

SDM:

LPOL:

PMEO:

CEL:	CELE_Y51H1A.2(cup-14)

CBR:	CBG_20680 CBG_20681

CRQ:	GCK72_005826

NAI:	NECAME_06043

LOA:	LOAG_16593 LOAG_16594

TSP:

Tsp_08057

LGI:	LOTGIDRAFT_236498

PVUL:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

MCAF:

MMER:

RPHI:

DPOL:

OBI:

OSN:

LAK:

NVE:

EPA:

ATEN:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_60242

AQU:

100633755

ACAN:

ACA1_175290

» show all

Reference

PMID:12820725

Authors

Hartel-Schenk S, Gratchev A, Hanski ML, Ogorek D, Trendelenburg G, Hummel M, Hopfner M, Scherubl H, Zeitz M, Hanski C

Title

Novel adapter protein AP162 connects a sialyl-Le(x)-positive mucin with an apoptotic signal transduction pathway.

Journal

Glycoconj J 18:915-23 (2001)
DOI:10.1023/a:1022256610674

Sequence

[hsa:9842]

LinkDB

DBGET integrated database retrieval system