Homo sapiens (human): 3356 Help Entry 3356              CDS       T01001                                  Symbol HTR2A, 5-HT2A, HTR2 Name (RefSeq) 5-hydroxytryptamine receptor 2A   KO K04157   5-hydroxytryptamine receptor 2 Organism hsa  Homo sapiens (human) Pathway hsa04020   Calcium signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04540   Gap junction hsa04726   Serotonergic synapse hsa04750   Inflammatory mediator regulation of TRP channels Network nt06528  Calcium signaling   Element N01640   GPCR-PLCB-ITPR signaling pathway Disease H01450   Obsessive-compulsive disorder H01611   Alcohol dependence H01646   Major depressive disorder H01649   Schizophrenia Drug target Adatanserin hydrochloride:  D02767 Altanserin tartrate:  D02836 Amesergide:  D02893 Aripiprazole (DG00906):  D01164<JP/US> D10355 D10364<US> D10516<JP/US> Asenapine (DG03100):  D02995<JP/US> D11769<US> Atiprosin maleate:  D03005 Blonanserin:  D01176<JP> Brexpiprazole:  D10309<JP/US> Brolamfetamine:  D12707 Cariprazine (DG01305):  D09876<US> D09997 Chlorpromazine (DG00867):  D00270 D00789<JP/US> D03274 D04034<JP> D09819 Cinitapride (DG01520):  D07700 D07701 Cisapride (DG00056):  D00274 D02092 Clozapine:  D00283<JP/US> Cyamemazine (DG00872):  D07307 D07756 Cyproheptadine (DG01109):  D02234<JP/US> D07765 Dimetotiazine (DG00843):  D01902<JP> D07854 Eplivanserin:  D10006 Esmirtazapine maleate:  D04055 Fananserin:  D02656 Fenfluramine (DG00103):  D04148<JP/US> D07945 Flibanserin:  D02577<US> Glemanserin:  D04320 Iloperidone:  D02666<US> Ketanserin (DG00265):  D02363 D08099 Loxapine (DG00897):  D00794<US> D02340<US> D08148 Lubazodone hydrochloride:  D04788 Lumateperone (DG02937):  D11169 D11170<US> Lurasidone:  D04820<JP/US> Mesoridazine (DG00883):  D00795 D02671 Methysergide (DG00835):  D00681 D02357 Metrenperone:  D05015 Mianserin (DG00951):  D01358<JP> D08216 Mirtazapine (DG02838):  D00563<JP/US> D11056 Mosapramine (DG00905):  D01548<JP> D08235 Naftidrofuryl (DG00290):  D05107 D08244 Nefazodone (DG00953):  D00819<US> D08257 Nelotanserin:  D09645 Ocaperidone:  D02675 Olanzapine (DG00898):  D00454<JP/US> D06623<US> Opipramol (DG00930):  D01477 D08297 Paliperidone (DG00907):  D05339<JP/US> D05340<JP/US> Pelanserin hydrochloride:  D05395 Periciazine:  D01485<JP> Perospirone hydrochloride hydrate:  D02372<JP> Pimavanserin:  D08969<US> Pipotiazine (DG00884):  D02680 D08385 Pizotifen (DG00842):  D05523 D08397 Pruvanserin (DG01278):  D06632 D06633 Psilocybin:  D12881 Quetiapine (DG00899):  D00458<JP/US> D08456 Risperidone:  D00426<JP/US> Ritanserin:  D05738 Sarpogrelate (DG01333):  D01624<JP> D08508 Sergolexole maleate:  D05829 Sertindole:  D00561 Setoperone:  D02686 Temanogrel (DG01334):  D09976 D09977 Tiospirone hydrochloride:  D02688 Trazodone (DG00952):  D00820<JP/US> D08626 Tropanserin hydrochloride:  D06253 Xylamidine tosylate:  D06343 Zicronapine (DG01539):  D10329 D10495 Ziprasidone (DG00892):  D01939<US> D02100<US> D08687 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04020 Calcium signaling pathway     3356 (HTR2A)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     3356 (HTR2A)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04540 Gap junction     3356 (HTR2A)  09150 Organismal Systems   09156 Nervous system    04726 Serotonergic synapse     3356 (HTR2A)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     3356 (HTR2A)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     3356 (HTR2A) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Biogenic amine    Serotonin     3356 (HTR2A) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srsx 7tm_4 7TM_GPCR_Srx Motif Other DBs NCBI-GeneID:  3356 NCBI-ProteinID:  NP_000612 OMIM:  182135 HGNC:  5293 Ensembl:  ENSG00000102468 Pharos:  P28223(Tclin) UniProt:  P28223 Structure PDBPDBj LinkDB All DBs Position 13:complement(46831546..46898082) Genome browser AA seq 471 aa AA seqDB search MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGC LSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF VSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIH REPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGA LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYK SSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV NT seq 1416 nt NT seq  +upstreamnt  +downstreamnt atggatattctttgtgaagaaaatacttctttgagctcaactacgaactccctaatgcaa ttaaatgatgacaccaggctctacagtaatgactttaactccggagaagctaacacttct gatgcatttaactggacagtcgactctgaaaatcgaaccaacctttcctgtgaagggtgc ctctcaccgtcgtgtctctccttacttcatctccaggaaaaaaactggtctgctttactg acagccgtagtgattattctaactattgctggaaacatactcgtcatcatggcagtgtcc ctagagaaaaagctgcagaatgccaccaactatttcctgatgtcacttgccatagctgat atgctgctgggtttccttgtcatgcccgtgtccatgttaaccatcctgtatgggtaccgg tggcctctgccgagcaagctttgtgcagtctggatttacctggacgtgctcttctccacg gcctccatcatgcacctctgcgccatctcgctggaccgctacgtcgccatccagaatccc atccaccacagccgcttcaactccagaactaaggcatttctgaaaatcattgctgtttgg accatatcagtaggtatatccatgccaataccagtctttgggctacaggacgattcgaag gtctttaaggaggggagttgcttactcgccgatgataactttgtcctgatcggctctttt gtgtcatttttcattcccttaaccatcatggtgatcacctactttctaactatcaagtca ctccagaaagaagctactttgtgtgtaagtgatcttggcacacgggccaaattagcttct ttcagcttcctccctcagagttctttgtcttcagaaaagctcttccagcggtcgatccat agggagccagggtcctacacaggcaggaggactatgcagtccatcagcaatgagcaaaag gcatgcaaggtgctgggcatcgtcttcttcctgtttgtggtgatgtggtgccctttcttc atcacaaacatcatggccgtcatctgcaaagagtcctgcaatgaggatgtcattggggcc ctgctcaatgtgtttgtttggatcggttatctctcttcagcagtcaacccactagtctac acactgttcaacaagacctataggtcagccttttcacggtatattcagtgtcagtacaag gaaaacaaaaaaccattgcagttaattttagtgaacacaataccggctttggcctacaag tctagccaacttcaaatgggacaaaaaaagaattcaaagcaagatgccaagacaacagat aatgactgctcaatggttgctctaggaaagcagcattctgaagaggcttctaaagacaat agcgacggagtgaatgaaaaggtgagctgtgtgtga

Homo sapiens (human): 3357 Help Entry 3357              CDS       T01001                                  Symbol HTR2B, 5-HT(2B), 5-HT-2B, 5-HT2B Name (RefSeq) 5-hydroxytryptamine receptor 2B   KO K04157   5-hydroxytryptamine receptor 2 Organism hsa  Homo sapiens (human) Pathway hsa04020   Calcium signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04540   Gap junction hsa04726   Serotonergic synapse hsa04750   Inflammatory mediator regulation of TRP channels Network nt06528  Calcium signaling   Element N01640   GPCR-PLCB-ITPR signaling pathway Drug target Adatanserin hydrochloride:  D02767 Brolamfetamine:  D12707 Chlorpromazine (DG00867):  D00270 D00789<JP/US> D03274 D04034<JP> D09819 Cinitapride (DG01520):  D07700 D07701 Cyproheptadine (DG01109):  D02234<JP/US> D07765 Dimetotiazine (DG00843):  D01902<JP> D07854 Flibanserin:  D02577<US> Glemanserin:  D04320 Iloperidone:  D02666<US> Methysergide (DG00835):  D00681 D02357 Metrenperone:  D05015 Mirtazapine (DG02838):  D00563<JP/US> D11056 Ocaperidone:  D02675 Olanzapine (DG00898):  D00454<JP/US> D06623<US> Opipramol (DG00930):  D01477 D08297 Pelanserin hydrochloride:  D05395 Periciazine:  D01485<JP> Pizotifen (DG00842):  D05523 D08397 Sergolexole maleate:  D05829 Setoperone:  D02686 Tiospirone hydrochloride:  D02688 Trazodone (DG00952):  D00820<JP/US> D08626 Tropanserin hydrochloride:  D06253 Xylamidine tosylate:  D06343 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04020 Calcium signaling pathway     3357 (HTR2B)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     3357 (HTR2B)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04540 Gap junction     3357 (HTR2B)  09150 Organismal Systems   09156 Nervous system    04726 Serotonergic synapse     3357 (HTR2B)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     3357 (HTR2B)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     3357 (HTR2B) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Biogenic amine    Serotonin     3357 (HTR2B) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srv 7tm_4 7TM_GPCR_Srx Motif Other DBs NCBI-GeneID:  3357 NCBI-ProteinID:  NP_000858 OMIM:  601122 HGNC:  5294 Ensembl:  ENSG00000135914 Pharos:  P41595(Tclin) UniProt:  P41595 Structure PDBPDBj LinkDB All DBs Position 2:complement(231108230..231125042) Genome browser AA seq 481 aa AA seqDB search MALSYRVSELQSTIPEHILQSTFVHVISSNWSGLQTESIPEEMKQIVEEQGNKLHWAALL ILMVIIPTIGGNTLVILAVSLEKKLQYATNYFLMSLAVADLLVGLFVMPIALLTIMFEAM WPLPLVLCPAWLFLDVLFSTASIMHLCAISVDRYIAIKKPIQANQYNSRATAFIKITVVW LISIGIAIPVPIKGIETDVDNPNNITCVLTKERFGDFMLFGSLAAFFTPLAIMIVTYFLT IHALQKKAYLVKNKPPQRLTWLTVSTVFQRDETPCSSPEKVAMLDGSRKDKALPNSGDET LMRRTSTIGKKSVQTISNEQRASKVLGIVFFLFLLMWCPFFITNITLVLCDSCNQTTLQM LLEIFVWIGYVSSGVNPLVYTLFNKTFRDAFGRYITCNYRATKSVKTLRKRSSKIYFRNP MAENSKFFKKHGIRNGINPAMYQSPMRLRSSTIQSSSIILLDTLLLTENEGDKTEEQVSY V NT seq 1446 nt NT seq  +upstreamnt  +downstreamnt atggctctctcttacagagtgtctgaacttcaaagcacaattcctgagcacattttgcag agcacctttgttcacgttatctcttctaactggtctggattacagacagaatcaatacca gaggaaatgaaacagattgttgaggaacagggaaataaactgcactgggcagctcttctg atactcatggtgataatacccacaattggtggaaatacccttgttattctggctgtttca ctggagaagaagctgcagtatgctactaattactttctaatgtccttggcggtggctgat ttgctggttggattgtttgtgatgccaattgccctcttgacaataatgtttgaggctatg tggcccctcccacttgttctatgtcctgcctggttatttcttgacgttctcttttcaacc gcatccatcatgcatctctgtgccatttcagtggatcgttacatagccatcaaaaagcca atccaggccaatcaatataactcacgggctacagcattcatcaagattacagtggtgtgg ttaatttcaataggcattgccattccagtccctattaaagggatagagactgatgtggac aacccaaacaatatcacttgtgtgctgacaaaggaacgttttggcgatttcatgctcttt ggctcactggctgccttcttcacacctcttgcaattatgattgtcacctactttctcact atccatgctttacagaagaaggcttacttagtcaaaaacaagccacctcaacgcctaaca tggttgactgtgtctacagttttccaaagggatgaaacaccttgctcgtcaccggaaaag gtggcaatgctggatggttctcgaaaggacaaggctctgcccaactcaggtgatgaaaca cttatgcgaagaacatccacaattgggaaaaagtcagtgcagaccatttccaacgaacag agagcctcaaaggtcctagggattgtgtttttcctctttttgcttatgtggtgtcccttc tttattacaaatataactttagttttatgtgattcctgtaaccaaactactctccaaatg ctcctggagatatttgtgtggataggctatgtttcctcaggagtgaatcctttggtctac accctcttcaataagacatttcgggatgcatttggccgatatatcacctgcaattaccgg gccacaaagtcagtaaaaactctcagaaaacgctccagtaagatctacttccggaatcca atggcagagaactctaagtttttcaagaaacatggaattcgaaatgggattaaccctgcc atgtaccagagtccaatgaggctccgaagttcaaccattcagtcttcatcaatcattcta ctagatacgcttctcctcactgaaaatgaaggtgacaaaactgaagagcaagttagttat gtatag

Homo sapiens (human): 3358 Help Entry 3358              CDS       T01001                                  Symbol HTR2C, 5-HT1C, 5-HT2C, 5-HTR2C, 5HTR2C, HTR1C Name (RefSeq) 5-hydroxytryptamine receptor 2C   KO K04157   5-hydroxytryptamine receptor 2 Organism hsa  Homo sapiens (human) Pathway hsa04020   Calcium signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04540   Gap junction hsa04726   Serotonergic synapse hsa04750   Inflammatory mediator regulation of TRP channels Network nt06528  Calcium signaling   Element N01640   GPCR-PLCB-ITPR signaling pathway Drug target Adatanserin hydrochloride:  D02767 Agomelatine:  D02578 Amesergide:  D02893 Asenapine (DG03100):  D02995<JP/US> Brolamfetamine:  D12707 Captodiame:  D07316 Chlorpromazine (DG00867):  D00270 D00789<JP/US> D03274 D04034<JP> D09819 Cinitapride (DG01520):  D07700 D07701 Clozapine:  D00283<JP/US> Cyamemazine (DG00872):  D07307 D07756 Cyproheptadine (DG01109):  D02234<JP/US> D07765 Dimetotiazine (DG00843):  D01902<JP> D07854 Fenfluramine (DG00103):  D04148<JP/US> D07945 Flibanserin:  D02577<US> Glemanserin:  D04320 Idalopirdine (DG01878):  D10710 Iloperidone:  D02666<US> Lorcaserin (DG03052):  D06613 D11566 Methysergide (DG00835):  D00681 D02357 Metrenperone:  D05015 Mianserin (DG00951):  D01358<JP> D08216 Mirtazapine (DG02838):  D00563<JP/US> D11056 Nefazodone (DG00953):  D00819<US> D08257 Ocaperidone:  D02675 Olanzapine (DG00898):  D00454<JP/US> D06623<US> Opipramol (DG00930):  D01477 D08297 Pelanserin hydrochloride:  D05395 Periciazine:  D01485<JP> Pimavanserin:  D08969<US> Pizotifen (DG00842):  D05523 D08397 Ritanserin:  D05738 Sergolexole maleate:  D05829 Setoperone:  D02686 Tedatioxetine (DG01311):  D10170 D10171 Tiospirone hydrochloride:  D02688 Trazodone (DG00952):  D00820<JP/US> D08626 Tropanserin hydrochloride:  D06253 Vabicaserin hydrochloride:  D06660 Xylamidine tosylate:  D06343 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04020 Calcium signaling pathway     3358 (HTR2C)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     3358 (HTR2C)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04540 Gap junction     3358 (HTR2C)  09150 Organismal Systems   09156 Nervous system    04726 Serotonergic synapse     3358 (HTR2C)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     3358 (HTR2C)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     3358 (HTR2C) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Biogenic amine    Serotonin     3358 (HTR2C) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srsx 7tm_4 7TM_GPCR_Srx DUF1385 UPF0182 Pox_P21 Motif Other DBs NCBI-GeneID:  3358 NCBI-ProteinID:  NP_000859 OMIM:  312861 HGNC:  5295 Ensembl:  ENSG00000147246 Pharos:  P28335(Tclin) UniProt:  P28335 Structure PDBPDBj LinkDB All DBs Position X:114584086..114910061 Genome browser AA seq 458 aa AA seqDB search MVNLRNAVHSFLVHLIGLLVWQSDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSI VIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVW PLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWA ISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYV LRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTM QAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVC SGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTN EPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV NT seq 1377 nt NT seq  +upstreamnt  +downstreamnt atggtgaacctgaggaatgcggtgcattcattccttgtgcacctaattggcctattggtt tggcaatctgatatttctgtgagcccagtagcagctatagtaactgacattttcaatacc tccgatggtggacgcttcaaattcccagacggggtacaaaactggccagcactttcaatc gtcatcataataatcatgacaataggtggcaacatccttgtgatcatggcagtaagcatg gaaaagaaactgcacaatgccaccaattacttcttaatgtccctagccattgctgatatg ctagtgggactacttgtcatgcccctgtctctcctggcaatcctttatgattatgtctgg ccactacctagatatttgtgccccgtctggatttctttagatgttttattttcaacagcg tccatcatgcacctctgcgctatatcgctggatcggtatgtagcaatacgtaatcctatt gagcatagccgtttcaattcgcggactaaggccatcatgaagattgctattgtttgggca atttctataggtgtatcagttcctatccctgtgattggactgagggacgaagaaaaggtg ttcgtgaacaacacgacgtgcgtgctcaacgacccaaatttcgttcttattgggtccttc gtagctttcttcataccgctgacgattatggtgattacgtattgcctgaccatctacgtt ctgcgccgacaagctttgatgttactgcacggccacaccgaggaaccgcctggactaagt ctggatttcctgaagtgctgcaagaggaatacggccgaggaagagaactctgcaaaccct aaccaagaccagaacgcacgccgaagaaagaagaaggagagacgtcctaggggcaccatg caggctatcaacaatgaaagaaaagcttcgaaagtccttgggattgttttctttgtgttt ctgatcatgtggtgcccatttttcattaccaatattctgtctgttctttgtgagaagtcc tgtaaccaaaagctcatggaaaagcttctgaatgtgtttgtttggattggctatgtttgt tcaggaatcaatcctctggtgtatactctgttcaacaaaatttaccgaagggcattctcc aactatttgcgttgcaattataaggtagagaaaaagcctcctgtcaggcagattccaaga gttgccgccactgctttgtctgggagggagcttaatgttaacatttatcggcataccaat gaaccggtgatcgagaaagccagtgacaatgagcccggtatagagatgcaagttgagaat ttagagttaccagtaaatccctccagtgtggttagcgaaaggattagcagtgtgtga

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