KEGG   PATHWAY: pvp04519
Entry
pvp04519                    Pathway                                
Name
Cadherin signaling - Pteropus vampyrus (large flying fox)
Description
Cadherins constitute a large superfamily of calcium-dependent cell-cell adhesion proteins that serve as critical determinants of the timing and specificity of cell interactions, migration, and morphogenetic processes. Many cadherins mediate mechanical coupling between adjacent cells by organizing highly ordered junctional complexes. Beyond their adhesive roles, cadherins act as signaling platforms that influence cell motility, proliferation, and gene expression.
Class
Environmental Information Processing; Signaling molecules and interaction
Pathway map
pvp04519  Cadherin signaling
pvp04519

Organism
Pteropus vampyrus (large flying fox) [GN:pvp]
Gene
105288356  ACTR3; actin-related protein 3 [KO:K18584]
105288407  DAAM2; disheveled-associated activator of morphogenesis 2 isoform X1 [KO:K04512]
105288428  PRICKLE4; prickle-like protein 4 isoform X2 [KO:K04511]
105288457  RYK; tyrosine-protein kinase RYK [KO:K05128] [EC:2.7.10.1]
105288774  [KO:K10367]
105288788  SCN5A; sodium channel protein type 5 subunit alpha [KO:K04838]
105288870  VCL; vinculin isoform X1 [KO:K05700]
105288933  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
105289211  ARPC3; actin-related protein 2/3 complex subunit 3 isoform X1 [KO:K05756]
105289220  PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit [KO:K06269] [EC:3.1.3.16]
105289256  TAOK3; serine/threonine-protein kinase TAO3 isoform X1 [KO:K04429] [EC:2.7.11.1]
105289288  MYO1B; unconventional myosin-Ib isoform X2 [KO:K10356]
105289326  MAPK1; mitogen-activated protein kinase 1 isoform X2 [KO:K04371] [EC:2.7.11.24]
105289435  LATS1; serine/threonine-protein kinase LATS1 [KO:K08791] [EC:2.7.11.1]
105289628  MAPK10; mitogen-activated protein kinase 10 [KO:K04440] [EC:2.7.11.24]
105289631  GABRR3; gamma-aminobutyric acid receptor subunit rho-3 [KO:K05190]
105289682  CDH18; cadherin-18 isoform X2 [KO:K06805]
105289683  CDH12; cadherin-12 [KO:K06804]
105289687  CDH10; cadherin-10 isoform X2 [KO:K06802]
105289688  CDH9; cadherin-9 isoform X1 [KO:K06801]
105289690  CDH6; cadherin-6 [KO:K06798]
105289830  CDH13; cadherin-13 isoform X1 [KO:K06808]
105289857  CDH8; cadherin-8 [KO:K06800]
105289859  CDH11; cadherin-11 isoform X1 [KO:K06803]
105289890  GABRG2; gamma-aminobutyric acid receptor subunit gamma-2 isoform X1 [KO:K05186]
105289891  GABRA1; gamma-aminobutyric acid receptor subunit alpha-1 isoform X1 [KO:K05175]
105289892  GABRA6; gamma-aminobutyric acid receptor subunit alpha-6 [KO:K05175]
105289942  WWC1; protein KIBRA [KO:K16685]
105289947  GABRB2; gamma-aminobutyric acid receptor subunit beta-2 [KO:K05181]
105289956  [KO:K05749]
105290156  WNT16; protein Wnt-16 [KO:K01558]
105290270  IGF1R; insulin-like growth factor 1 receptor [KO:K05087] [EC:2.7.10.1]
105290328  CTNNB1; catenin beta-1 [KO:K02105]
105290379  LIMD1; LIM domain-containing protein 1 [KO:K16682]
105290433  CDC42; cell division control protein 42 homolog isoform X1 [KO:K04393]
105290434  WNT4; protein Wnt-4 [KO:K00408]
105290711  CTNNA2; catenin alpha-2 isoform X1 [KO:K05691]
105290745  MOB1A; MOB kinase activator 1A isoform X1 [KO:K06685]
105290991  PRICKLE2; prickle-like protein 2 isoform X3 [KO:K04511]
105291051  WNT10A; protein Wnt-10a [KO:K01357]
105291052  WNT6; protein Wnt-6 isoform X2 [KO:K00445]
105291072  ARPC2; actin-related protein 2/3 complex subunit 2 [KO:K05758]
105291105  DES; LOW QUALITY PROTEIN: desmin [KO:K07610]
105291165  GJA1; gap junction alpha-1 protein [KO:K07372]
105291480  TCF7L2; transcription factor 7-like 2 isoform X8 [KO:K04491]
105291512  FZD3; frizzled-3 isoform X1 [KO:K02329]
105291579  DCHS2; protocadherin-23 [KO:K16507]
105291733  DVL2; segment polarity protein dishevelled homolog DVL-2 isoform X1 [KO:K02353]
105291865  MYO1C; unconventional myosin-Ic [KO:K10356]
105291867  YWHAE; 14-3-3 protein epsilon [KO:K06630]
105291895  TAOK1; serine/threonine-protein kinase TAO1 isoform X1 [KO:K04429] [EC:2.7.11.1]
105291902  NCKAP1; nck-associated protein 1 [KO:K05750]
105291963  MYO1D; unconventional myosin-Id isoform X2 [KO:K10356]
105292147  LATS2; serine/threonine-protein kinase LATS2 [KO:K08791] [EC:2.7.11.1]
105292221  PTK2B; protein-tyrosine kinase 2-beta [KO:K05871] [EC:2.7.10.2]
105292257  CDH2; cadherin-2 isoform X1 [KO:K06736]
105292284  ROCK1; rho-associated protein kinase 1 isoform X1 [KO:K04514] [EC:2.7.11.39]
105292405  MOB1B; MOB kinase activator 1B [KO:K06685]
105292586  ENAH; protein enabled homolog isoform X7 [KO:K05746]
105292607  PSEN2; presenilin-2 [KO:K04522] [EC:3.4.23.-]
105292722  CDH20; cadherin-20 [KO:K06807]
105293004  LEF1; lymphoid enhancer-binding factor 1 isoform X1 [KO:K04492]
105293029  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
105293146  PCDH15; protocadherin-15 [KO:K16500]
105293336  USH1G; Usher syndrome type-1G protein isoform X1 [KO:K21878]
105293362  DSG2; desmoglein-2 [KO:K07597]
105293370  DSG3; desmoglein-3 [KO:K07598]
105293375  DSG4; desmoglein-4 [KO:K07599]
105293382  DSG1; desmoglein-1 [KO:K07596]
105293390  DSC1; desmocollin-1 isoform X1 [KO:K07600]
105293394  TMC8; transmembrane channel-like protein 8 isoform X3 [KO:K21988]
105293399  DSC3; desmocollin-3 isoform X1 [KO:K07602]
105293443  TMC6; transmembrane channel-like protein 6 [KO:K21988]
105293453  PCDH18; protocadherin-18 isoform X3 [KO:K16499]
105293457  PCDH10; protocadherin-10 isoform X2 [KO:K28836]
105293567  TCF7; transcription factor 7 isoform X2 [KO:K02620]
105293607  WNT8A; protein Wnt-8a [KO:K00714]
105293725  DSC2; desmocollin-2 [KO:K07601]
105293771  KDR; vascular endothelial growth factor receptor 2 [KO:K05098] [EC:2.7.10.1]
105293808  PDGFRA; platelet-derived growth factor receptor alpha [KO:K04363] [EC:2.7.10.1]
105293897  GABRG1; gamma-aminobutyric acid receptor subunit gamma-1 [KO:K05186]
105293898  GABRB1; gamma-aminobutyric acid receptor subunit beta-1 isoform X1 [KO:K05181]
105293915  GABRA2; gamma-aminobutyric acid receptor subunit alpha-2 isoform X1 [KO:K05175]
105293917  GABRA4; gamma-aminobutyric acid receptor subunit alpha-4 [KO:K05175]
105294059  KRAS; GTPase KRas isoform X2 [KO:K07827]
105294097  PKP2; plakophilin-2 [KO:K12642]
105294187  FZD4; frizzled-4 [KO:K02354]
105294199  FAT3; protocadherin Fat 3 [KO:K16506]
105294256  APH1B; gamma-secretase subunit APH-1B isoform X3 [KO:K06172]
105294280  ADAM10; disintegrin and metalloproteinase domain-containing protein 10 [KO:K06704] [EC:3.4.24.81]
105294322  MYO1E; unconventional myosin-Ie [KO:K10356]
105294515  SHOC2; leucine-rich repeat protein SHOC-2 [KO:K19613]
105294552  FZD1; frizzled-1 [KO:K02432]
105294565  ACTB; actin, cytoplasmic 1 isoform X1 [KO:K05692]
105294623  RAC1; LOW QUALITY PROTEIN: ras-related C3 botulinum toxin substrate 1 [KO:K04392]
105294725  FAT1; LOW QUALITY PROTEIN: protocadherin Fat 1 [KO:K16506]
105294783  CTNND2; catenin delta-2 [KO:K23491]
105294862  ARPC5L; actin-related protein 2/3 complex subunit 5-like protein [KO:K05754]
105294910  VIM; vimentin [KO:K07606]
105294978  WNT7A; protein Wnt-7a [KO:K00572]
105295039  ARPC5; actin-related protein 2/3 complex subunit 5 [KO:K05754]
105295263  WASF1; wiskott-Aldrich syndrome protein family member 1 [KO:K05753]
105295461  ROCK2; LOW QUALITY PROTEIN: rho-associated protein kinase 2 [KO:K17388] [EC:2.7.11.39]
105295478  APC; adenomatous polyposis coli protein isoform X3 [KO:K02085]
105295526  LHFPL3; LHFPL tetraspan subfamily member 3 protein isoform X1 [KO:K23893]
105295572  MPDZ; multiple PDZ domain protein isoform X1 [KO:K06095]
105295944  ATN1; atrophin-1 isoform X1 [KO:K05626]
105296044  PCDH7; protocadherin-7 [KO:K16498]
105296104  CDH7; cadherin-7 [KO:K06799]
105296109  CDH19; LOW QUALITY PROTEIN: cadherin-19 [KO:K06806]
105296550  NRAS; GTPase NRas isoform X1 [KO:K07828]
105296755  DSP; desmoplakin isoform X1 [KO:K10381]
105296814  WNT2B; protein Wnt-2b isoform X1 [KO:K00182]
105296901  PKP1; plakophilin-1 isoform X1 [KO:K10387]
105296974  ANKRD6; ankyrin repeat domain-containing protein 6 isoform X1 [KO:K21435]
105296978  GABRR2; gamma-aminobutyric acid receptor subunit rho-2 isoform X1 [KO:K05190]
105296979  GABRR1; gamma-aminobutyric acid receptor subunit rho-1 isoform X1 [KO:K05190]
105297011  [KO:K16494]
105297012  [KO:K16494]
105297013  [KO:K16494]
105297014  [KO:K16494]
105297015  [KO:K16494]
105297016  [KO:K16494]
105297034  PCDH1; protocadherin-1 isoform X1 [KO:K16498]
105297036  PCDH12; protocadherin-12 [KO:K16499]
105297065  [KO:K16494]
105297066  [KO:K16494]
105297068  [KO:K16494]
105297069  [KO:K16494]
105297071  [KO:K16495]
105297256  WNT5B; protein Wnt-5b isoform X1 [KO:K00444]
105297278  TEAD4; transcriptional enhancer factor TEF-3 isoform X1 [KO:K09448]
105297317  ARHGAP35; rho GTPase-activating protein 35 [KO:K05732]
105297337  VASP; vasodilator-stimulated phosphoprotein isoform X6 [KO:K06274]
105297483  PRICKLE1; prickle-like protein 1 isoform X2 [KO:K04511]
105297527  WNT10B; protein Wnt-10b [KO:K01357]
105297529  WNT1; proto-oncogene Wnt-1 [KO:K03209]
105297561  LIMA1; LIM domain and actin-binding protein 1 isoform X1 [KO:K23026]
105297627  WNT11; protein Wnt-11 [KO:K01384]
105297647  MYO7A; unconventional myosin-VIIa [KO:K10359]
105297659  RERE; arginine-glutamic acid dipeptide repeats protein isoform X1 [KO:K05628]
105297749  AXIN2; axin-2 [KO:K04385]
105297936  VANGL1; vang-like protein 1 [KO:K04510]
105297999  RELA; transcription factor p65 [KO:K04735]
105298051  EP300; histone acetyltransferase p300 isoform X1 [KO:K04498] [EC:2.3.1.48]
105298105  CELSR2; cadherin EGF LAG seven-pass G-type receptor 2 [KO:K04601]
105298116  FZD7; frizzled-7 [KO:K02432]
105298133  VAV3; guanine nucleotide exchange factor VAV3 [KO:K05730]
105298190  CDH22; cadherin-22 [KO:K06812]
105298225  YWHAB; 14-3-3 protein beta/alpha [KO:K16197]
105298276  YAP1; transcriptional coactivator YAP1 isoform X1 [KO:K16687]
105298400  FZD5; frizzled-5 [KO:K02375]
105298425  ABI2; abl interactor 2 isoform X1 [KO:K05751]
105298541  TCF7L1; transcription factor 7-like 1 isoform X1 [KO:K04490]
105299021  RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
105299036  BRK1; protein BRICK1 [KO:K05752]
105299048  ARPC4; actin-related protein 2/3 complex subunit 4 isoform X2 [KO:K05755]
105299059  LHFPL4; LHFPL tetraspan subfamily member 4 protein [KO:K23893]
105299132  PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit isoform X1 [KO:K06269] [EC:3.1.3.16]
105299254  PSEN1; presenilin-1 [KO:K04505] [EC:3.4.23.-]
105299292  TMC2; transmembrane channel-like protein 2 [KO:K21988]
105299316  GABRP; gamma-aminobutyric acid receptor subunit pi [KO:K05189]
105299374  ERBIN; erbin isoform X1 [KO:K12796]
105299427  CSNK1A1; casein kinase I isoform X1 [KO:K08957] [EC:2.7.11.1]
105299436  PDGFRB; platelet-derived growth factor receptor beta isoform X1 [KO:K05089] [EC:2.7.10.1]
105299469  FAT2; protocadherin Fat 2 [KO:K28839]
105299483  TMC1; transmembrane channel-like protein 1 [KO:K21988]
105299568  FZD10; frizzled-10 [KO:K02842]
105299684  FZD9; frizzled-9 [KO:K02842]
105299698  YWHAG; 14-3-3 protein gamma [KO:K16198]
105299863  WNT5A; protein Wnt-5a isoform X5 [KO:K00444]
105299936  CDH15; cadherin-15 [KO:K06809]
105299958  WNT3A; protein Wnt-3a [KO:K00312]
105299978  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
105300002  WNT9A; protein Wnt-9a [KO:K01064]
105300011  FLT4; vascular endothelial growth factor receptor 3 [KO:K05097] [EC:2.7.10.1]
105300184  ACTN4; alpha-actinin-4 isoform X1 [KO:K05699]
105300269  MET; hepatocyte growth factor receptor isoform X1 [KO:K05099] [EC:2.7.10.1]
105300315  FGFR1; fibroblast growth factor receptor 1 isoform X1 [KO:K04362] [EC:2.7.10.1]
105300527  AJUBA; LIM domain-containing protein ajuba isoform X1 [KO:K16682]
105300532  CDH24; cadherin-24 isoform X1 [KO:K06814]
105300612  STK3; serine/threonine-protein kinase 3 isoform X1 [KO:K04412]
105300704  VANGL2; vang-like protein 2 [KO:K04510]
105300707  NCSTN; nicastrin isoform X1 [KO:K06171]
105300873  FZD6; frizzled-6 isoform X1 [KO:K02376]
105300925  NF2; merlin isoform X2 [KO:K16684]
105301022  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [KO:K07209] [EC:2.7.11.10]
105301028  TEAD3; transcriptional enhancer factor TEF-5 [KO:K09448]
105301035  MAPK14; mitogen-activated protein kinase 14 isoform X1 [KO:K04441] [EC:2.7.11.24]
105301036  MAPK13; mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
105301053  LHFPL5; LHFPL tetraspan subfamily member 5 protein [KO:K23893]
105301110  VAV1; proto-oncogene vav [KO:K05730]
105301137  RAC3; ras-related C3 botulinum toxin substrate 3 [KO:K07861]
105301152  ACTG1; actin, cytoplasmic 2 [KO:K05692]
105301304  GSK3B; glycogen synthase kinase-3 beta isoform X1 [KO:K03083] [EC:2.7.11.26]
105301474  TEAD1; transcriptional enhancer factor TEF-1 isoform X7 [KO:K09448]
105301479  RRAS2; ras-related protein R-Ras2 [KO:K07830]
105301604  LHFPL1; LHFPL tetraspan subfamily member 1 protein isoform X2 [KO:K23893]
105301616  CIB2; calcium and integrin-binding family member 2 isoform X2 [KO:K23837]
105301651  TMC3; transmembrane channel-like protein 3 [KO:K21988]
105301701  CTNNA3; catenin alpha-3 [KO:K05691]
105301735  RRAS; ras-related protein R-Ras [KO:K07829]
105301748  TEAD2; transcriptional enhancer factor TEF-4 isoform X1 [KO:K09448]
105301904  AMOTL1; angiomotin-like protein 1 [KO:K06104]
105302044  WNT7B; protein Wnt-7b [KO:K00572]
105302259  APC2; adenomatous polyposis coli protein 2 [KO:K02085]
105302287  EVL; ena/VASP-like protein isoform X4 [KO:K23487]
105302383  RHOA; transforming protein RhoA [KO:K04513]
105302416  CELSR3; cadherin EGF LAG seven-pass G-type receptor 3 [KO:K04602]
105302532  IKBKG; NF-kappa-B essential modulator [KO:K07210]
105302556  MYO1A; unconventional myosin-Ia isoform X1 [KO:K10356]
105302623  NCKAP1L; nck-associated protein 1-like isoform X3 [KO:K05750]
105302673  KRT18; keratin, type I cytoskeletal 18 [KO:K07604]
105302675  KRT8; LOW QUALITY PROTEIN: keratin, type II cytoskeletal 8 [KO:K07605]
105302676  KRT78; keratin, type II cytoskeletal 78 [KO:K07605]
105302677  KRT79; keratin, type II cytoskeletal 79 [KO:K07605]
105302678  KRT4; keratin, type II cytoskeletal 4 [KO:K07605]
105302679  KRT3; keratin, type II cytoskeletal 3 [KO:K07605]
105302682  KRT2; keratin, type II cytoskeletal 2 epidermal [KO:K07605]
105302683  KRT1; keratin, type II cytoskeletal 1 [KO:K07605]
105302684  [KO:K07605]
105302685  KRT72; keratin, type II cytoskeletal 72 isoform X1 [KO:K07605]
105302686  KRT74; keratin, type II cytoskeletal 74 [KO:K07605]
105302687  KRT71; keratin, type II cytoskeletal 71 [KO:K07605]
105302688  KRT5; keratin, type II cytoskeletal 5 [KO:K07605]
105302705  [KO:K07605]
105302706  [KO:K07605]
105302714  FAT4; protocadherin Fat 4 [KO:K16669]
105302799  LRP6; low-density lipoprotein receptor-related protein 6 [KO:K03068]
105302907  YWHAZ; 14-3-3 protein zeta/delta [KO:K16197]
105302942  [KO:K05730]
105303098  CREBBP; CREB-binding protein [KO:K04498] [EC:2.3.1.48]
105303182  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
105303252  AXIN1; axin-1 isoform X1 [KO:K02157]
105303453  WNT3; proto-oncogene Wnt-3 [KO:K00312]
105303454  WNT9B; protein Wnt-9b [KO:K01064]
105303480  FZD2; frizzled-2 [KO:K02235]
105303543  LHFPL2; LHFPL tetraspan subfamily member 2 protein [KO:K23893]
105303599  DVL1; segment polarity protein dishevelled homolog DVL-1 [KO:K02353]
105303608  GABRD; gamma-aminobutyric acid receptor subunit delta [KO:K05184]
105303711  AFDN; afadin [KO:K05702]
105303733  TMC7; transmembrane channel-like protein 7 [KO:K21988]
105303734  TMC5; transmembrane channel-like protein 5 [KO:K21988]
105303767  ACTR3B; actin-related protein 3B isoform X1 [KO:K18584]
105303783  LHFPL6; LHFPL tetraspan subfamily member 6 protein isoform X1 [KO:K23893]
105303962  MYO1H; LOW QUALITY PROTEIN: unconventional myosin-Ih [KO:K10356]
105304012  [KO:K16498]
105304165  MAP2K3; dual specificity mitogen-activated protein kinase kinase 3 [KO:K04432] [EC:2.7.12.2]
105304220  USH1C; harmonin isoform X2 [KO:K21877]
105304558  TAOK2; serine/threonine-protein kinase TAO2 isoform X2 [KO:K04429] [EC:2.7.11.1]
105304566  MAPK3; mitogen-activated protein kinase 3 isoform X1 [KO:K04371] [EC:2.7.11.24]
105304619  CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1 [KO:K04467] [EC:2.7.11.10]
105304667  WNT8B; protein Wnt-8b [KO:K00714]
105304738  CTNND1; catenin delta-1 isoform X3 [KO:K05690]
105305694  CDH16; cadherin-16 isoform X3 [KO:K06810]
105305755  CDH3; cadherin-3 [KO:K06796]
105305756  CDH1; cadherin-1 isoform X1 [KO:K05689]
105305762  CDH5; cadherin-5 [KO:K06533]
105305784  GABRA5; gamma-aminobutyric acid receptor subunit alpha-5 [KO:K05175]
105305785  CYFIP1; cytoplasmic FMR1-interacting protein 1 [KO:K05749]
105305788  [KO:K05186]
105305888  CELSR1; cadherin EGF LAG seven-pass G-type receptor 1 [KO:K04600]
105305927  PKP3; plakophilin-3 isoform X1 [KO:K28841]
105305933  HRAS; GTPase HRas isoform X1 [KO:K02833]
105306059  AMOTL2; angiomotin-like protein 2 isoform X1 [KO:K06104]
105306067  PCDH9; protocadherin-9 isoform X1 [KO:K16498]
105306093  PCDH20; protocadherin-20 [KO:K16498]
105306131  PCDH17; protocadherin-17 isoform X1 [KO:K16499]
105306141  [KO:K04361] [EC:2.7.10.1]
105306153  PCDH8; protocadherin-8 isoform X1 [KO:K28835]
105306170  [KO:K05181]
105306315  JUP; junction plakoglobin isoform X3 [KO:K10056]
105306317  [KO:K07604]
105306318  [KO:K07604]
105306319  KRT15; keratin, type I cytoskeletal 15 [KO:K07604]
105306320  KRT19; keratin, type I cytoskeletal 19 [KO:K07604]
105306321  KRT13; keratin, type I cytoskeletal 13 [KO:K07604]
105306322  KRT36; keratin, type I cuticular Ha6 [KO:K07604]
105306323  KRT35; keratin, type I cuticular Ha5 [KO:K07604]
105306324  KRT32; keratin, type I cuticular Ha2 [KO:K07604]
105306325  [KO:K07604]
105306326  [KO:K07604]
105306328  KRT34; keratin, type I cuticular Ha4 [KO:K07604]
105306329  [KO:K07604]
105306330  [KO:K07604]
105306340  [KO:K07604]
105306578  LRP5; low-density lipoprotein receptor-related protein 5 [KO:K03068]
105306620  SCN1B; sodium channel subunit beta-1 isoform X1 [KO:K04845]
105306650  PSENEN; gamma-secretase subunit PEN-2 [KO:K06170]
105306687  ACTR2; actin-related protein 2 [KO:K17260]
105306744  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
105306984  PCDHB1; protocadherin beta-1 [KO:K16494]
105306985  PCDHAC1; protocadherin alpha-C1 [KO:K16493]
105306986  [KO:K16493]
105306987  [KO:K16493]
105306988  [KO:K16493]
105306989  [KO:K16493]
105306990  [KO:K16493]
105306994  CTNNA1; catenin alpha-1 [KO:K05691]
105307000  [KO:K07605]
105307001  [KO:K07605]
105307002  KRT84; keratin, type II cuticular Hb4 [KO:K07605]
105307003  KRT85; keratin, type II cuticular Hb5 isoform X1 [KO:K07605]
105307004  [KO:K07605]
105307006  [KO:K07605]
105307007  KRT7; keratin, type II cytoskeletal 7 [KO:K07605]
105307029  KRT82; keratin, type II cuticular Hb2 [KO:K07605]
105307030  [KO:K07605]
105307034  KRT80; keratin, type II cytoskeletal 80 [KO:K07605]
105307126  DVL3; segment polarity protein dishevelled homolog DVL-3 isoform X1 [KO:K02353]
105307149  FZD8; frizzled-8 [KO:K02375]
105307468  CDH4; cadherin-4 [KO:K06797]
105307480  SCN3B; sodium channel subunit beta-3 [KO:K04847]
105307493  PPP1R1B; protein phosphatase 1 regulatory subunit 1B isoform X1 [KO:K15494]
105307498  ERBB2; receptor tyrosine-protein kinase erbB-2 [KO:K05083] [EC:2.7.10.1]
105307531  KRT24; keratin, type I cytoskeletal 24 isoform X1 [KO:K07604]
105307532  KRT26; keratin, type I cytoskeletal 26 [KO:K07604]
105307533  [KO:K07604]
105307534  KRT10; keratin, type I cytoskeletal 10 isoform X1 [KO:K07604]
105307535  KRT12; keratin, type I cytoskeletal 12 [KO:K07604]
105307536  KRT23; keratin, type I cytoskeletal 23 [KO:K07604]
105307537  KRT39; keratin, type I cytoskeletal 39 [KO:K07604]
105307549  KRT25; keratin, type I cytoskeletal 25 [KO:K07604]
105307550  [KO:K07604]
105307551  [KO:K07604]
105307552  KRT40; keratin, type I cytoskeletal 40 [KO:K07604]
105307731  MYO1F; unconventional myosin-If [KO:K10356]
105307748  PTK2; focal adhesion kinase 1 [KO:K05725] [EC:2.7.10.2]
105308049  ACTN1; alpha-actinin-1 isoform X1 [KO:K05699]
105308071  PCDH19; protocadherin-19 isoform X2 [KO:K28837]
105308189  GABRE; gamma-aminobutyric acid receptor subunit epsilon [KO:K05185]
105308191  GABRA3; gamma-aminobutyric acid receptor subunit alpha-3 [KO:K05175]
105308196  GABRQ; gamma-aminobutyric acid receptor subunit theta [KO:K05192]
105308212  VAV2; guanine nucleotide exchange factor VAV2 [KO:K05730]
105308249  MPP5; MAGUK p55 subfamily member 5 isoform X1 [KO:K06091]
105308283  [KO:K04441] [EC:2.7.11.24]
105308338  YWHAH; 14-3-3 protein eta [KO:K16198]
105308412  CDH17; cadherin-17 [KO:K06811]
105308466  WNT2; protein Wnt-2 [KO:K00182]
105308697  APH1A; gamma-secretase subunit APH-1A [KO:K06172]
105308765  MYO1G; unconventional myosin-Ig [KO:K10356]
105308953  [KO:K07831]
105309046  PRICKLE3; prickle planar cell polarity protein 3 isoform X1 [KO:K04511]
105309105  DCHS1; protocadherin-16 [KO:K16507]
105309151  TJP1; tight junction protein ZO-1 [KO:K05701]
105309257  SCN4B; sodium channel subunit beta-4 [KO:K04848]
105309258  SCN2B; sodium channel subunit beta-2 [KO:K04846]
105309437  ARPC1B; actin-related protein 2/3 complex subunit 1B [KO:K05757]
105309438  ARPC1A; actin-related protein 2/3 complex subunit 1A [KO:K05757]
105309469  TMC4; transmembrane channel-like protein 4 [KO:K21988]
105309642  WWTR1; WW domain-containing transcription regulator protein 1 [KO:K16820]
105309827  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1 [KO:K04368] [EC:2.7.12.2]
105309924  PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit [KO:K06269] [EC:3.1.3.16]
105310026  [KO:K05181]
105310076  DAAM1; disheveled-associated activator of morphogenesis 1 [KO:K04512]
105310250  SAV1; protein salvador homolog 1 [KO:K16686]
105310491  [KO:K07604]
105310717  [KO:K16494]
105311532  RAC2; ras-related C3 botulinum toxin substrate 2 isoform X2 [KO:K07860]
111732552  PCDHAC2; protocadherin alpha-C2 [KO:K16493]
111732553  [KO:K16493]
111744375  [KO:K16495]
111744376  [KO:K16495]
111744378  [KO:K16494]
Reference
PMID:37255594
  Authors
Lin WH, Cooper LM, Anastasiadis PZ
  Title
Cadherins and catenins in cancer: connecting cancer pathways and tumor microenvironment.
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Front Cell Dev Biol 11:1137013 (2023)
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Reference
PMID:37970977
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Structural basis of molecular recognition among classical cadherins mediating cell adhesion.
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Biochem Soc Trans 51:2103-2115 (2023)
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Developmental functions of the P120-catenin sub-family.
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J Clin Invest 123:1419-22 (2013)
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Molecular mechanisms of arrhythmogenic cardiomyopathy.
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Nat Rev Cardiol 16:519-537 (2019)
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Biophys Rev 13:697-706 (2021)
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Reference
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Protocadherins at the Crossroad of Signaling Pathways.
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Front Mol Neurosci 13:117 (2020)
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PMID:21173574
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Non-clustered protocadherin.
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Cell Adh Migr 5:97-105 (2011)
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PMID:23481195
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Delta-protocadherins in health and disease.
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Prog Mol Biol Transl Sci 116:169-92 (2013)
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Mechanisms in cochlear hair cell mechano-electrical transduction for acquisition of sound frequency and intensity.
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Cell Mol Life Sci 78:5083-5094 (2021)
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PMID:22069509
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Caberlotto E, Michel V, de Monvel JB, Petit C
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Coupling of the mechanotransduction machinery and F-actin polymerization in the cochlear hair bundles.
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Bioarchitecture 1:169-174 (2011)
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PMID:29421162
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  Title
The tip link protein Cadherin-23: From Hearing Loss to Cancer.
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Pharmacol Res 130:25-35 (2018)
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Reference
PMID:28603077
  Authors
Aviles EC, Goodrich LV
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Configuring a robust nervous system with Fat cadherins.
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Semin Cell Dev Biol 69:91-101 (2017)
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Reference
PMID:27942226
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Zhang X, Liu J, Liang X, Chen J, Hong J, Li L, He Q, Cai X
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History and progression of Fat cadherins in health and disease.
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Onco Targets Ther 9:7337-7343 (2016)
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Reference
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The Hippo Pathway in Cardiac Regeneration and Homeostasis: New Perspectives for Cell-Free Therapy in the Injured Heart.
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Biomolecules 10:biom10071024 (2020)
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Reference
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Cells 13:cells13242116 (2024)
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Related
pathway
pvp04010  MAPK signaling pathway
pvp04064  NF-kappa B signaling pathway
pvp04151  PI3K-Akt signaling pathway
pvp04310  Wnt signaling pathway
pvp04390  Hippo signaling pathway
pvp04520  Adherens junction
pvp04630  JAK-STAT signaling pathway
pvp04810  Regulation of actin cytoskeleton
KO pathway
ko04519   

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