| D00136 |
Haloperidol (JP18/USP/INN); Haldol (TN) |
(P) CYP inhibition: CYP2D6 |
| D00184 |
Cyclosporine (USP); Ciclosporin (JP18); Gengraf (TN); Neoral (TN); Restasis (TN); Sandimmune (TN) |
(P) unclassified |
| D00211 |
Rifampin (USP); Rifampicin (JP18/INN); Rifadin (TN); Rimactane (TN) |
(CI,P) unclassified |
| D00252 |
Carbamazepine (JP18/USP/INN); Equetro (TN); Tegretol (TN) |
(P) unclassified |
| D00293 |
Diazepam (JP18/USP/INN); Diastat (TN); Valium (TN) |
(P) unclassified |
| D00350 |
Itraconazole (JP18/USP); Itrizole (TN); Sporanox (TN) |
(P) unclassified |
| D00387 |
Triazolam (JP18/USP/INN); Halcion (TN) |
(CI) unclassified |
| D00426 |
Risperidone (JP18/USP/INN); Risperdal (TN) |
(P) CYP inhibition: CYP2D6 |
| D00434 |
Simvastatin (JP18/USP/INN); MK-733; Zocor (TN) |
(CI) unclassified |
| D00435 |
Nevirapine (JAN/USP/INN); Viramune (TN) |
(P) CYP inhibition: CYP2D6 |
| D00506 |
Phenobarbital (JP18/USP/INN); Luminal (TN) |
(P) CYP induction: CYP3A |
| D00512 |
Phenytoin (JP18/USP/INN); Dilantin (TN) |
(P) CYP induction: CYP3A |
| D00550 |
Midazolam (JAN/USP/INN); Dormicum (TN); Buccolam (TN); Nayzilam (TN) |
(CI) unclassified |
| D00570 |
Colchicine (JP18/USP); Colchicine (TN) |
(P) Transporter inhibition: ABCB1 |
| D00603 |
Timolol maleate (JP18/USP); Blocadren (TN); Istalol (TN); Timoptic (TN) |
(P) CYP inhibition: CYP2D6 |
| D00661 |
Cevimeline hydrochloride (USAN); Cevimeline hydrochloride hydrate (JAN); Evoxac (TN); Saligren (TN) |
(P) CYP inhibition: CYP2D6 |
| D00670 |
Donepezil hydrochloride (JP18/USP); Aricept (TN) |
(P) unclassified |
| D00680 |
Methylergonovine maleate (USP); Methylergometrine maleate (JP18); Methergine (TN) |
(CI) unclassified |
| D00701 |
Phenobarbital sodium (JAN/USP/INN); Luminal sodium (TN) |
(P) CYP induction: CYP3A |
| D00809 |
Amitriptyline hydrochloride (JP18/USP); Elavil (TN) |
(P) CYP inhibition: CYP2D6 |
| D00848 |
Dextromethorphan hydrobromide (USP); Dextromethorphan hydrobromide hydrate (JP18); Benylin DM (TN) |
(P) CYP inhibition: CYP2D6 |
| D01061 |
Irinotecan hydrochloride (USP); Irinotecan hydrochloride hydrate (JP18); Irinotecan hydrochloride trihydrate; CPT 11; CPT-11; Campto (TN); Camptosar (TN); Onivyde (TN) |
(P) unclassified |
| D01145 |
Azelnidipine (JP18/INN); Calblock (TN) |
(CI) unclassified |
| D01164 |
Aripiprazole (JAN/USP/INN); Abilify (TN) |
(P) CYP inhibition: CYP2D6 |
| D01167 |
Magnesium oxide (JP18/USP); Magmitt (TN) |
(P) unclassified |
| D01176 |
Blonanserin (JAN/INN); AD 5423 |
(CI) unclassified |
| D01213 |
Tolvaptan (JAN/USAN/INN); Samsca (TN) |
(P) Transporter inhibition: ABCB1 |
| D01227 |
Bosentan (USAN); Bosentan hydrate (JAN); Tracleer (TN) |
(P) unclassified |
| D01253 |
Clobazam (JAN/USAN/INN); Mystan (TN); Onfi (TN) |
(P) unclassified |
| D01280 |
Warfarin potassium (JP18); Athrombin-K (TN) |
(P) unclassified |
| D01898 |
Haloperidol decanoate (JAN/USP); Halomonth (TN) |
(P) CYP inhibition: CYP2D6 |
| D02008 |
Tadalafil (JAN/USP/INN); Adcirca (TN); Cialis (TN); Zalutia (TN) |
(CI) unclassified |
| D02103 |
Phenytoin sodium (USP); Phenytoin sodium for injection (JP18); Aleviatin (TN); Dilantin (TN) |
(P) CYP induction: CYP3A |
| D02229 |
Sildenafil citrate (JAN/USP); Revatio (TN); Viagra (TN) |
(CI) unclassified |
| D02484 |
Artemether and lumefantrine; Coartem (TN) |
(P) Enzyme: CYP3A / CYP inhibition: CYP3A |
| D02574 |
Atomoxetine hydrochloride (JAN/USP); Tomoxetine hydrochloride; Strattera (TN) |
(P) CYP inhibition: CYP2D6 |
| D02691 |
Somatropin (USP/INN); Somatropin (genetical recombination) (JAN); Human growth hormone (JAN); Asellacrin (TN); Humatrope (TN); Nutropin (TN); Omnitrope (TN) |
(P) unclassified |
| D02714 |
Everolimus (JAN/USAN/INN); Afinitor (TN); Votubia (TN); Zortress (TN) |
(P) Transporter inhibition: ABCB1 |
| D03106 |
Bexarotene (JAN/USAN/INN); Targretin (TN) |
(P) CYP induction: CYP3A |
| D03260 |
Vardenafil hydrochloride hydrate (JAN); Vardenafil monohydrochloride trihydrate; Levitra (TN); Staxyn (TN) |
(CI) unclassified |
| D04024 |
Lapatinib ditosylate (USAN); Lapatinib tosilate hydrate (JAN); Lapatinib ditosylate monohydrate; Tykerb (TN); Tyverb (TN) |
(P) Transporter inhibition: ABCB1 |
| D04148 |
Fenfluramine hydrochloride (JAN/USAN); Fintepla (TN); Pondimin (TN) |
(P) CYP inhibition: CYP2D6 |
| D04340 |
Dextromethorphan hydrobromide and potassium cresolsulfonate; Medicon (TN) |
(P) CYP inhibition: CYP2D6 |
| D04484 |
Desogestrel and ethinylestradiol; Marvelon21 (TN); Ortho-cept (TN) |
(P) unclassified |
| D04641 |
Istradefylline (JAN/USAN/INN); Nourianz (TN); Nouriast (TN) |
(P) unclassified |
| D04768 |
Lonafarnib (JAN/USAN/INN); Zokinvy (TN) |
(CI,P) unclassified |
| D04820 |
Lurasidone hydrochloride (JAN/USAN); SM 13496; Latuda (TN) |
(CI) unclassified |
| D05775 |
Rufinamide (JAN/USP/INN); Banzel (TN) |
(P) unclassified |
| D06068 |
Temsirolimus (JAN/USAN/INN); Torisel (TN) |
(P) unclassified |
| D06199 |
Trabectedin (JAN/USAN/INN); Yondelis (TN) |
(P) unclassified |
| D06412 |
Aliskiren fumarate (JAN/USAN); Aliskiren hemifumarate; Tekturna (TN) |
(P) Transporter inhibition: ABCB1 |
| D06637 |
Romidepsin (JAN/USAN/INN); Istodax (TN) |
(P) Enzyme: CYP3A / CYP inhibition: CYP3A |
| D07082 |
Dabigatran etexilate mesylate (USAN); Dabigatran etexilate methanesulfonate (JAN); Dabigatran etexilate mesilate; Pradaxa (TN) |
(CI,P) Transporter inhibition: ABCB1 |
| D07086 |
Rivaroxaban (JAN/USAN/INN); Xarelto (TN) |
(CI) Transporter inhibition: ABCB1 |
| D07505 |
Latanoprost and timolol maleate; Xalacom (TN) |
(P) unclassified |
| D07583 |
Phenytoin and phenobarbital; Aleviatin with phenobarbital (TN) |
(P) CYP induction: CYP3A |
| D07585 |
Isopropylantipyrine, ergotamine tartrate and anhydrous caffeine; Cleamine A (TN) |
(CI) unclassified |
| D07595 |
Fosphenytoin sodium hydrate (JAN); Fostoin (TN) |
(P) unclassified |
| D07869 |
Donepezil (JAN/INN); Donaz (TN); Allydone (TN) |
(P) unclassified |
| D08095 |
Ivabradine hydrochloride (JAN/USAN); Ivabrandine hydrochloride; Corlanor (TN); Corlentor (TN); Coralan (TN) |
(CI,P) unclassified |
| D08493 |
Dorzolamide hydrochloride and timolol maleate (JP18); Cosopt (TN) |
(P) CYP inhibition: CYP2D6 |
| D08575 |
Tetrabenazine (JAN/INN); Nitoman (TN); Xenazine (TN) |
(P) CYP inhibition: CYP2D6 |
| D08856 |
Anamorelin hydrochloride (JAN/USAN); Adlumiz (TN) |
(CI) unclassified |
| D08923 |
Fesoterodine fumarate (JAN/USAN); Toviaz (TN) |
(P) CYP inhibition: CYP2D6 |
| D09017 |
Ticagrelor (JAN/USAN/INN); Brilinta (TN) |
(CI,P) Enzyme: CYP3A / CYP inhibition: CYP3A / Transporter inhibition: ABCB1 |
| D09319 |
Indacaterol maleate (JAN/USAN); Arcapta neohaler (TN) |
(P) Transporter inhibition: ABCB1 |
| D09348 |
Fostamatinib disodium (USAN); Fostamatinib sodium hydrate (JAN); Fostamatinib disodium hexahydrate; Tavalisse (TN) |
(P) CYP inhibition: CYP3A |
| D09535 |
Mirabegron (JAN/USAN/INN); Myrbetriq (TN) |
(P) unclassified |
| D09546 |
Edoxaban tosilate hydrate (JAN); Edoxaban tosylate monohydrate; Lixiana (TN); Savaysa (TN) |
(P) Transporter inhibition: ABCB1 |
| D09572 |
Riociguat (JAN/USAN/INN); Adempas (TN) |
(P) Enzyme: CYP3A / CYP inhibition: CYP3A / Transporter inhibition: ABCB1 |
| D09594 |
Olmesartan medoxomil and azelnidipine; Rezaltas (TN) |
(CI) unclassified |
| D09638 |
Lomitapide mesylate (USAN); Lomitapide mesilate (JAN); Juxtapid (TN); Lojuxta (TN) |
(CI,P) unclassified |
| D09701 |
Abiraterone acetate (JAN/USP); Zytiga (TN) |
(P) unclassified |
| D09728 |
Bosutinib hydrate (JAN); Bosutinib monohydrate; Bosulif (TN) |
(P) unclassified |
| D09730 |
Olaparib (JAN/USAN/INN); Lynparza (TN) |
(P) Enzyme: CYP3A / CYP inhibition: CYP3A |
| D09731 |
Crizotinib (JAN/USAN/INN); Xalkori (TN) |
(P) CYP inhibition: CYP3A |
| D09733 |
Afatinib dimaleate (USAN); Afatinib maleate (JAN); Gilotrif (TN); Giotrif (TN) |
(P) Transporter inhibition: ABCB1 |
| D09815 |
Travoprost and timolol maleate; Duotrav (TN) |
(P) unclassified |
| D09894 |
Eliglustat tartrate (JAN/USAN); Eliglustat hemitartrate; Cerdelga (TN) |
(CI,P) CYP inhibition: CYP2D6 / Transporter inhibition: ABCB1 |
| D09920 |
Lenvatinib mesylate (USAN); Lenvatinib mesilate (JAN); Lenvima (TN) |
(P) Enzyme: CYP3A / CYP inhibition: CYP3A / Transporter inhibition: ABCB1 |
| D09951 |
Ponatinib hydrochloride (JAN/USAN); Iclusig (TN) |
(P) Enzyme: CYP3A / CYP inhibition: CYP3A |
| D09956 |
Quizartinib dihydrochloride (USAN); Quizartinib hydrochloride (JAN); Vanflyta (TN) |
(P) Enzyme: CYP3A / CYP inhibition: CYP3A |
| D10003 |
Hemin (JAN); Normosang (TN); Panhematin (TN) |
(P) unclassified |
| D10024 |
Selumetinib sulfate (JAN/USAN); Koselugo (TN) |
(P) unclassified |
| D10082 |
Suvorexant (JAN/USAN); MK-4305; Belsomra (TN) |
(P) Enzyme: CYP3A / CYP inhibition: CYP3A |
| D10095 |
Cabozantinib s-malate (USAN); Cabozantinib malate (JAN); Cometriq (TN); Cabometyx (TN) |
(P) unclassified |
| D10104 |
Dabrafenib mesylate (USAN); Dabrafenib mesilate (JAN); Tafinlar (TN) |
(P) unclassified |
| D10185 |
Vortioxetine hydrobromide (JAN/USAN); Brintellix (TN); Trintellix (TN) |
(P) CYP inhibition: CYP2D6 |
| D10223 |
Ibrutinib (JAN/USAN); Imbruvica (TN) |
(P) Enzyme: CYP3A / CYP inhibition: CYP3A |
| D10298 |
Brimonidine tartrate and timolol maleate; Combigan (TN); Aibeta (TN) |
(P) unclassified |
| D10309 |
Brexpiprazole (JAN/USAN/INN); Rexulti (TN) |
(P) CYP inhibition: CYP2D6 |
| D10372 |
Palbociclib (JAN/USAN); Ibrance (TN) |
(P) unclassified |
| D10396 |
Nintedanib esylate (USAN); Nintedanib ethanesulfonate (JAN); Ofev (TN) |
(P) Transporter inhibition: ABCB1 |
| D10450 |
Alectinib hydrochloride (JAN); Alecensa (TN) |
(P) unclassified |
| D10452 |
Cabazitaxel acetonate (JAN); Cabazitaxel acetone; Jevtana (TN) |
(P) Enzyme: CYP3A / CYP inhibition: CYP3A |
| D10478 |
Naldemedine tosylate (JAN/USAN); Naldemedine tosilate; Symproic (TN) |
(P) unclassified |
| D10505 |
Glycopyrronium bromide and indacaterol maleate; Ultibro (TN) |
(P) Transporter inhibition: ABCB1 |
| D10512 |
Brinzolamide and timolol maleate; Azorga (TN) |
(P) CYP inhibition: CYP2D6 |
| D10514 |
Dacomitinib (USAN); Dacomitinib hydrate (JAN); Vizimpro (TN) |
(P) unclassified |
| D10516 |
Aripiprazole hydrate (JAN); Aripiprazole monohydrate; Abilify maintena (TN) |
(P) CYP inhibition: CYP2D6 |
| D10551 |
Ceritinib (JAN/USAN/INN); Zykadia (TN) |
(P) Enzyme: CYP3A / CYP inhibition: CYP3A |
| D10564 |
Amenamevir (JAN/INN); Amenalief (TN) |
(P) Enzyme: CYP3A / CYP inhibition: CYP3A / CYP induction: CYP3A |
| D10569 |
Tafluprost and timolol maleate; Tapcom (TN) |
(P) unclassified |
| D10633 |
Finerenone (JAN/USAN/INN); Kerendia (TN) |
(CI,P) unclassified |
| D10643 |
Isavuconazonium sulfate (JAN/USAN); Cresemba (TN) |
(CI,P) Enzyme: CYP3A / CYP inhibition: CYP3A |
| D10679 |
Venetoclax (JAN/USAN/INN); Venclexta (TN) |
(CI,P) unclassified |
| D10688 |
Abemaciclib (JAN/USAN/INN); Verzenio (TN) |
(P) Enzyme: CYP3A / CYP inhibition: CYP3A |
| D10727 |
Sodium zirconium cyclosilicate (USAN); Sodium zirconium cyclosilicate hydrate (JAN); Lokelma (TN) |
(P) unclassified |
| D10733 |
Talazoparib tosylate (USAN); Talazoparib tosilate (JAN); Talzenna (TN) |
(P) unclassified |
| D10761 |
Polatuzumab vedotin (USAN); Polatuzumab vedotin (genetical recombination) (JAN); Polatuzumab vedotin-piiq; Polivy (TN) |
(P) Enzyme: CYP3A / CYP inhibition: CYP3A |
| D10762 |
Fosravuconazole L-lysine ethanolate (JAN) |
(P) CYP inhibition: CYP3A |
| D10780 |
Perampanel hydrate (JAN); Fycompa (TN) |
(P) Enzyme: CYP3A / CYP inhibition: CYP3A |
| D10800 |
Gilteritinib fumarate (JAN/USAN); Xospata (TN) |
(P) Transporter inhibition: ABCB1 |
| D10801 |
Letermovir (JAN/USAN/INN); Prevymis (TN) |
(P) CYP inhibition: CYP3A |
| D10866 |
Brigatinib (JAN/USAN); Alunbrig (TN) |
(P) unclassified |
| D10891 |
Capmatinib hydrochloride (USAN); Capmatinib hydrochloride hydrate (JAN); Tabrecta (TN) |
(P) unclassified |
| D10892 |
Esaxerenone (JAN/INN) |
(P) Enzyme: CYP3A / CYP inhibition: CYP3A |
| D10893 |
Acalabrutinib (JAN/USAN/INN); Calquence (TN) |
(P) Enzyme: CYP3A / CYP inhibition: CYP3A |
| D10926 |
Entrectinib (JAN/USAN/INN); Rozlytrek (TN) |
(P) CYP inhibition: CYP3A |
| D10990 |
Somatrogon (USAN/INN); Somatrogon (genetical recombination) (JAN); Somatrogon-ghla; Ngenla (TN) |
(P) unclassified |
| D10993 |
Tucidinostat (JAN/USAN/INN); Hiyasta (TN) |
(P) unclassified |
| D10999 |
Valbenazine tosylate (USAN); Valbenazine tosilate (JAN); Valbenazine ditosylate; Ingrezza (TN); Dysval (TN) |
(P) unclassified |
| D11012 |
Lorlatinib (JAN/USAN/INN); Lorbrena (TN) |
(P) Enzyme: CYP3A / CYP inhibition: CYP3A / CYP induction: CYP3A |
| D11022 |
Lemborexant (JAN/USAN/INN); Dayvigo (TN) |
(P) unclassified |
| D11027 |
Ropeginterferon alfa-2b (INN); Ropeginterferon alfa-2b (genetical recombination) (JAN); Ropeginterferon alfa-2b-njft; Besremi (TN) |
(P) unclassified |
| D11040 |
Apalutamide (JAN/INN); Erleada (TN) |
(P) unclassified |
| D11048 |
Upadacitinib hydrate (JAN); Upadacitinib hemihydrate; Rinvoq (TN) |
(P) unclassified |
| D11053 |
Encorafenib (JAN/USAN/INN); Braftovi (TN) |
(P) unclassified |
| D11070 |
Tirabrutinib hydrochloride (JAN/USAN); Velexbru (TN) |
(P) unclassified |
| D11138 |
Larotrectinib sulfate (JAN/USAN); Vitrakvi (TN) |
(P) Enzyme: CYP3A / CYP inhibition: CYP3A |
| D11194 |
Somapacitan (USAN/INN); Somapacitan (genetical recombination) (JAN); Somapacitan-beco; Sogroya (TN) |
(P) unclassified |
| D11370 |
Fosnetupitant chloride hydrochloride (JAN/USAN); Arokaris (TN) |
(P) unclassified |
| D11417 |
Pemigatinib (JAN/USAN/INN); Pemazyre (TN) |
(P) unclassified |
| D11485 |
Tazemetostat hydrobromide (JAN/USAN); Tazverik (TN) |
(P) Transporter inhibition: ABCB1 |
| D11525 |
Enfortumab vedotin (USAN); Enfortumab vedotin (genetical recombination) (JAN); Enfortumab vedotin-ejfv; Padcev (TN) |
(P) unclassified |
| D11659 |
Tolvaptan sodium phosphate (JAN); Samtasu (TN) |
(P) unclassified |
| D11662 |
Valemetostat tosilate (JAN); Valemetostat tosylate; Ezharmia (TN) |
(P) unclassified |
| D11674 |
Berotralstat hydrochloride (JAN/USAN); Orladeyo (TN) |
(P) Transporter inhibition: ABCB1 |
| D11708 |
Givosiran sodium (JAN); Givlaari (TN) |
(P) unclassified |
| D11713 |
Selpercatinib (JAN/USAN/INN); Retevmo (TN) |
(P) unclassified |
| D11725 |
Futibatinib (JAN/USAN/INN); Lytgobi (TN) |
(P) unclassified |
| D11861 |
Indacaterol acetate, glycopyrronium bromide and mometasone furoate; Enerzair (TN) |
(P) unclassified |
| D11862 |
Indacaterol and mometasone furoate; Atectura (TN) |
(P) unclassified |
| D11920 |
Pimitespib (JAN); Jeselhy (TN) |
(P) CYP inhibition: CYP3A |
| D11970 |
Ritlecitinib tosylate (USAN); Ritlecitinib tosilate (JAN); Litfulo (TN) |
(P) CYP inhibition: CYP3A |
| D12055 |
Sotorasib (JAN/USAN); Lumakras (TN) |
(P) Enzyme: CYP3A / CYP inhibition: CYP3A |
| D12586 |
Mifepristone and misoprostol; Mefeego (TN) |
(P) Enzyme: CYP3A / CYP inhibition: CYP3A |
