KEGG ORTHOLOGY: K10646

ORTHOLOGY: K10646

Entry

K10646                      KO

Symbol

TRAF7, RFWD1

Name

E3 ubiquitin-protein ligase TRAF7 [EC:2.3.2.27]

Disease

H01556

Meningioma

H02715

Neurodevelopmental disorder with defects of ubiquitin-proteasome system

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K10646  TRAF7, RFWD1; E3 ubiquitin-protein ligase TRAF7
Enzymes [BR:ko01000]
2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     K10646  TRAF7, RFWD1; E3 ubiquitin-protein ligase TRAF7
Ubiquitin system [BR:ko04121]
Ubiquitin ligases (E3)
  Single Ring-finger type E3
   TRAF proteins
    K10646  TRAF7, RFWD1; E3 ubiquitin-protein ligase TRAF7

Genes

HSA:	84231(TRAF7)

PTR:	467870(TRAF7)

PPS:	100980562(TRAF7)

GGO:	101133974(TRAF7)

PON:	100443205(TRAF7)

PPYG:

129015974(TRAF7)

NLE:	100605568(TRAF7)

HMH:	116462499(TRAF7)

SSYN:

129461719(TRAF7)

MCC:	695415(TRAF7)

MCF:	102145269(TRAF7)

MTHB:

126944623

MNI:	105485812(TRAF7)

CSAB:

103226666(TRAF7)

CATY:

105573473(TRAF7)

PANU:

100997219(TRAF7)

TGE:	112613802(TRAF7)

MLEU:

105529751(TRAF7)

RRO:	104681541(TRAF7)

RBB:	108519452(TRAF7)

TFN:	117097806(TRAF7)

PTEH:

111524064(TRAF7)

CANG:

105526416(TRAF7)

CJC:	100389216(TRAF7)

SBQ:	101028181(TRAF7)

CIMI:

108290928(TRAF7)

ANAN:

105707336 105709830(TRAF7)

CSYR:

103252724(TRAF7)

MMUR:

105859639(TRAF7)

LCAT:

123631488(TRAF7)

PCOQ:

105813065(TRAF7)

OGA:	100958178(TRAF7)

MMU:	224619(Traf7)

MCAL:

110312501(Traf7)

MPAH:

110337858(Traf7)

RNO:	360491(Traf7)

MCOC:

116076982(Traf7)

ANU:	117710492(Traf7)

ASYL:

127694136(Traf7)

MUN:	110553015(Traf7)

CGE:	100756531(Traf7)

MAUA:

101831078(Traf7)

PROB:

127219558(Traf7)

PLEU:

114680742(Traf7) 114710003

MORG:

121463716(Traf7)

MFOT:

126496971 126510750

AAMP:

119813195(Traf7)

NGI:	103743707(Traf7)

HGL:	101711929(Traf7)

CPOC:

100733170(Traf7)

CCAN:

109690160(Traf7)

DORD:

105982192(Traf7)

DSP:	122123786(Traf7)

DMER:

138814627 138825441

PLOP:

125340377(Traf7)

NCAR:

124970137

MMMA:

107146717(Traf7)

ITI:	101966559(Traf7)

OCU:

127488860

OPI:	101524128(TRAF7) 105942039

TUP:	102485123(TRAF7)

GVR:	103597890(TRAF7)

CFA:	609824(TRAF7)

CLUD:

112640542(TRAF7)

VVP:	112909064(TRAF7)

VLG:	121487454(TRAF7)

NPO:	129519388(TRAF7)

AML:	100466273(TRAF7)

UMR:	103668781(TRAF7)

UAH:	113245092(TRAF7)

UAR:	123783743(TRAF7)

ELK:

111156018

LLV:

125090272

MPUF:

101693830(TRAF7)

MNP:	132027021(TRAF7)

MLK:	131819181(TRAF7)

NVS:	122895271(TRAF7)

ORO:	101373071(TRAF7)

EJU:	114215549(TRAF7)

ZCA:	113932327(TRAF7)

MLX:	118021721(TRAF7)

NSU:	110587850(TRAF7)

LWW:	102750638(TRAF7)

FCA:	101082031(TRAF7)

PYU:	121019678(TRAF7)

PCOO:

112853201(TRAF7)

PBG:	122471818(TRAF7)

PVIV:

125154456(TRAF7)

LRUF:

124525488

LGF:	123589636(TRAF7)

AJU:

106978706

PTG:	102956752(TRAF7)

PPAD:

109278149(TRAF7)

PUC:

125927181

PLEZ:

122209511(TRAF7)

HHV:	120241523(TRAF7)

BTA:	511692(TRAF7)

BOM:	102275075(TRAF7)

BIU:	109578631(TRAF7)

BBUB:

102416426(TRAF7)

BBIS:

104988486(TRAF7)

CHX:	102171477(TRAF7)

OAS:	101114158(TRAF7)

BTAX:

128069172(TRAF7)

CSUM:

138075767(TRAF7)

ODA:	120873446(TRAF7)

CCAD:

122433084(TRAF7)

MREE:

136160434(TRAF7)

OVR:	110147215(TRAF7)

MBEZ:

129545266(TRAF7)

SSC:	100516964(TRAF7)

CFR:	102523859(TRAF7)

CBAI:

105064850(TRAF7)

CDK:	105099712(TRAF7)

VPC:	102525441(TRAF7)

BACU:

103018310(TRAF7)

BMUS:

118881882(TRAF7)

LVE:	103087175(TRAF7)

OOR:	101275593(TRAF7)

LALB:

132506385(TRAF7)

GMF:	115848154(TRAF7)

DDP:	132437920(TRAF7)

DLE:	111185182(TRAF7)

PCAD:

102983479(TRAF7)

PSIU:

116739580(TRAF7)

PPHC:

136134814(TRAF7)

NASI:

112409462(TRAF7)

ECB:	100065698(TRAF7)

EPZ:	103566785(TRAF7)

EAI:	106836237(TRAF7)

MYB:	102255089(TRAF7)

MYD:	102757615(TRAF7)

MMYO:

118656096(TRAF7)

MLF:	102424230(TRAF7)

MDT:	132232935(TRAF7)

MYUM:

139009173(TRAF7)

PKL:	118703570(TRAF7)

EFUS:

103290592(TRAF7)

MNA:	107533376(TRAF7)

DRO:	112298306(TRAF7)

SHON:

118978800(TRAF7)

AJM:	119058244(TRAF7)

PDIC:

114497411(TRAF7)

PHAS:

123807216(TRAF7)

MMF:	118641396(TRAF7)

PPAM:

129083601(TRAF7)

HAI:	109385871(TRAF7)

RFQ:	117019555(TRAF7)

PALE:

102880087(TRAF7)

PGIG:

120620260(TRAF7)

PVP:	105303341(TRAF7)

RAY:	107506046(TRAF7)

MJV:	108406998(TRAF7)

TOD:	119242026(TRAF7)

SARA:

101538974(TRAF7)

SFUM:

130042947(TRAF7)

SETR:

126001341(TRAF7)

LAV:	100662879(TRAF7)

TMU:

101349942

ETF:	101664332(TRAF7)

DNM:	101416773(TRAF7)

MDO:	100011568(TRAF7)

GAS:	123231017(TRAF7)

SHR:	100919132(TRAF7)

AFZ:

127543422

PCW:	110221871(TRAF7)

TVP:	118831147(TRAF7)

PBRV:

138142051(TRAF7)

MLAO:

141495654(TRAF7)

OAA:	103167726(TRAF7)

TACU:

119942722(TRAF7)

GGA:	416555(TRAF7)

PCOC:

116237364(TRAF7)

MGP:	100543112(TRAF7)

CJO:	107320737(TRAF7)

TPAI:

128078991(TRAF7)

LMUT:

125700777(TRAF7)

NMEL:

110405724(TRAF7)

APLA:

101798472(TRAF7)

ACYG:

106046041(TRAF7)

CATA:

118256460(TRAF7)

AFUL:

116495448(TRAF7)

TGU:	100221244(TRAF7)

LSR:	110482114(TRAF7)

SCAN:

103817569(TRAF7)

PMOA:

120513056(TRAF7)

OTC:	121334592(TRAF7)

PRUF:

121365852(TRAF7)

ATRC:

139598421(TRAF7)

GFR:	102040054(TRAF7)

FAB:	101808366(TRAF7)

OMA:	130259208(TRAF7)

PHI:	102111263(TRAF7)

PMAJ:

107211133(TRAF7)

CCAE:

111936189(TRAF7)

CCW:	104684742(TRAF7)

CBRC:

103615374(TRAF7)

ACOE:

138118638(TRAF7)

ETL:	114064337(TRAF7)

ZAB:	102064331(TRAF7)

ZLE:	135454263(TRAF7)

ACHL:

103804315(TRAF7)

SVG:	106859299(TRAF7)

MMEA:

130576500(TRAF7)

HRT:	120759532(TRAF7)

SATI:

136368005(TRAF7)

CCIC:

134050523(TRAF7)

FPG:	101920032(TRAF7)

FCH:	102055101(TRAF7)

CCRI:

104158585(TRAF7)

NNT:	104412643(TRAF7)

SHAB:

115606843(TRAF7)

ACUN:

113485571(TRAF7)

TALA:

104367607(TRAF7)

ACHC:

115335845(TRAF7)

HALD:

104324352(TRAF7)

HLE:	104833654(TRAF7)

AGEN:

126034022

HHAR:

128134742(TRAF7)

CSTI:

104559210(TRAF7)

LDI:	104346050(TRAF7)

MNB:	103770664(TRAF7)

DPUB:

104297232(TRAF7)

PPUS:

135180747(TRAF7)

AVIT:

104271189(TRAF7)

BRHI:

104496244(TRAF7)

EGZ:	104134522(TRAF7)

NNI:	104015146(TRAF7)

PCRI:

104029949(TRAF7)

PCAO:

104045910

PADL:

103921408(TRAF7)

AFOR:

103904936(TRAF7)

FGA:	104082379(TRAF7)

GSTE:

104255603(TRAF7)

CBOY:

140658891(TRAF7)

CLV:	102097954(TRAF7)

CNIC:

135994528(TRAF7)

MUI:	104543046(TRAF7)

PGUU:

104471723(TRAF7)

PLET:

104622059(TRAF7)

EHS:	104503501(TRAF7)

CMAC:

104482750(TRAF7)

CUCA:

104060397(TRAF7)

TEO:	104382939(TRAF7)

BREG:

104642663(TRAF7)

OHA:	104326994(TRAF7)

ACAR:

104531933(TRAF7)

CPEA:

104393143(TRAF7)

CVF:	104295007(TRAF7)

RTD:	128913903(TRAF7)

CRID:

134519664(TRAF7)

AAM:	106486209(TRAF7)

AROW:

112975496(TRAF7)

NPD:	112959898(TRAF7)

TGT:	104580957(TRAF7)

DNE:	112985375(TRAF7)

SCAM:

104138627(TRAF7)

ASN:	102381153(TRAF7)

AMJ:	102570563(TRAF7)

CPOO:

109314616(TRAF7)

GGN:	109294407(TRAF7)

PSS:	102453922(TRAF7)

CMY:	102946912(TRAF7)

CCAY:

125644403(TRAF7)

DCC:	119862034(TRAF7)

CPIC:

101932666(TRAF7)

TST:	117883618(TRAF7)

CABI:

116823691(TRAF7)

MRV:	120373236(TRAF7)

ACS:	100564557(traf7)

ASAO:

132781929(TRAF7)

PVT:	110085043(TRAF7)

SUND:

121914782(TRAF7)

PBI:	103050486(TRAF7)

PMUR:

107293673(TRAF7)

CTIG:

120310850(TRAF7)

TSR:	106546841(TRAF7)

PGUT:

117667310(TRAF7)

PCAE:

139325230(TRAF7)

APRI:

131185019(TRAF7)

PTEX:

113438621(TRAF7)

NSS:	113423116(TRAF7)

VKO:	123034814(TRAF7)

PMUA:

114584253(TRAF7)

PRAF:

128401881(TRAF7)

ZVI:	118092817(TRAF7)

HCG:	128336417(TRAF7)

GJA:	107125588(TRAF7)

STOW:

125431844(TRAF7)

EMC:	129338692(TRAF7)

XLA:	108701653(traf7.L) 379974(traf7.S)

XTR:	100216042(traf7)

NPR:	108791426(TRAF7)

RTEM:

120943282(TRAF7)

ACAT:

141148760(TRAF7)

BBUF:

121008455(TRAF7)

BGAR:

122945776(TRAF7)

DTC:	141069568(TRAF7)

PWL:	138261096(TRAF7)

MUO:	115475570(TRAF7)

GSH:	117345464(TRAF7)

DRE:	563746(traf7)

SRX:	107719978 107721517

SANH:

107654453

SGH:	107590399 107601260

CCAR:

109050251 109064531(traf7)

CAUA:

113044696 113047339 113070449

CGIB:

127951023 127952902

PTET:

122342007(traf7)

LROH:

127163571(traf7)

GRF:	141334411(traf7)

OMC:	131538070(traf7)

PPRM:

120489892(traf7)

RKG:	130075829(traf7)

MAMB:

125271362(traf7)

CIDE:

127508337

CERY:

137017722(traf7)

MASI:

127450158 127451441

TROS:

130561018(traf7)

TDW:	130425550(traf7)

MANU:

129434161(traf7)

PDAB:

135737731

IPU:

108258537

IFU:	128622157(traf7)

PHYP:

113528441(traf7)

SMEO:

124396309(traf7)

TFD:	113659198(traf7)

TVC:	132860932(traf7)

CGAR:

128545017(traf7)

NGRA:

132868426(traf7)

TRN:	134336109(traf7)

AMEX:

103038327(traf7)

CMAO:

118821091(traf7)

EEE:

113582212

CHAR:

105900011(traf7)

SPIL:

134076337(traf7)

TRU:	101068227(traf7)

TFS:	130515500(traf7)

TNG:	GSTEN00026177G001

LCO:	104928989(traf7)

TBEN:

117492104(traf7)

CGOB:

115012375(traf7)

EMAC:

134878449(traf7)

ELY:	117268644(traf7)

EFO:	125879284(traf7)

PLEP:

121956791(traf7)

SLUC:

116063747(traf7)

ECRA:

117957701(traf7)

ESP:	116703355(traf7)

PFLV:

114569247(traf7)

GAT:	120827454(traf7)

PPUG:

119220150(traf7)

AFB:	129098633(traf7)

CLUM:

117734873(traf7)

PSWI:

130189371(traf7)

CANA:

137786578(traf7)

CVE:	137874190(traf7)

MSAM:

119882789(traf7)

SCHU:

122868955(traf7)

CUD:	121529440(traf7)

SPUL:

138603010(traf7)

LMIX:

132995262(traf7)

ALAT:

119014243(traf7)

ASTR:

137609903(traf7)

MZE:	101486481(traf7)

ONL:	100701367(traf7)

OAU:	116309427(traf7)

OLA:	101168715(traf7)

OML:	112138559(traf7)

CSAI:

133422165(traf7)

XMA:	102218966(traf7)

XCO:	114148338(traf7)

XHE:	116735766(traf7)

PRET:

103468319(traf7)

PFOR:

103152592(traf7)

PLAI:

106952977(traf7)

PMEI:

106932993(traf7)

GAF:	122821397(traf7)

PPRL:

129363902(traf7)

CVG:	107097836(traf7)

CTUL:

119772708(traf7)

GMU:	124863346 124865004

NFU:	107396408(traf7)

KMR:	108247524(traf7)

ALIM:

106517804(traf7) 106524413

NWH:	119421983(traf7)

AOCE:

111569312(traf7)

EJA:	138198411(traf7)

BFRE:

138627654(traf7)

MCEP:

124997792(traf7)

CSEM:

103393627(traf7)

POV:	109640874 109646130(traf7)

SSEN:

122763031(traf7)

SSOE:

131475682(traf7)

HHIP:

117766361(traf7)

HSP:	118123451(traf7)

PPLT:

128458906(traf7)

SMAU:

118288509(traf7)

LCF:

108898677

SDU:	111223709(traf7)

SLAL:

111662458(traf7)

XGL:	120783212(traf7)

HCQ:	109530035(traf7)

SSCV:

125983038(traf7)

SBIA:

133514752(traf7)

PEE:	133414969(traf7)

PTAO:

133465402(traf7)

BPEC:

110171837(traf7)

ENY:	140358623(traf7)

MALB:

109967583(traf7)

BSPL:

114859784(traf7)

SJO:	128378792(traf7)

SSCO:

133999512(traf7)

GMH:	115561510(traf7)

SASA:

106568433(traf7)

OTW:	112251951(traf7)

OMY:	110511701 110517092

OGO:	124020848(traf7) 124021411

OKI:

109886679

OKE:

127924272

OMM:	135538772(traf7)

OCLA:

139365265 139422374

CCLU:

121555970(traf7)

ELS:	105030335(traf7)

OEP:	134016636(traf7)

SFM:	108927143(traf7)

PKI:	111845529(traf7)

AANG:

118218691(traf7)

AROT:

135248238(traf7)

CCOG:

133113157(traf7)

LOC:	102691355(traf7)

PSPA:

121300781 121330823

ARUT:

117418490 117431238

PSEX:

120543107(traf7)

LCM:	102360774(TRAF7)

CMK:	103187103(traf7)

RTP:	109914467(traf7)

CPLA:

122560520(traf7)

HOC:	132825366(traf7)

LERI:

129706972(traf7)

HAKA:

140735320(traf7)

PMRN:

116949629 116956081(TRAF7)

LRJ:	133346766 133347996(TRAF7)

BFO:

118429095

BBEL:

109463287

CIN:	778871(zf(traf/ring)-5)

SCLV:

120346381

SPU:	100891365 575835

LPIC:

129268947

AJJ:	139960240 139961911

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:	100373941 102806950

PFLL:

139147948 139152078 139152087

HRO:	HELRODRAFT_190506

LGI:	LOTGIDRAFT_108875 LOTGIDRAFT_210287

PVUL:

126815543 126819697

PCAN:

112556789 112576699

LSAX:

138960210

BGT:	106051216 106068930

GAE:	121379396 121388975

HRF:	124113018 124114026

HRJ:	124260279 124288118

HASI:

137258002 137284993

HCRA:

139454244 139468575

CRG:	105328601 105329468

CANU:

128165307 128187644

CVN:

111136414

OED:

125666164

MYI:	110443744 110446163

PMAX:

117325781 117337427

AIRR:

138322970

MCAF:

127710291

MMER:

123534709 123550701 128551698

RPHI:

132720753 132725077

DPOL:

127846670 127863387 127866673

MAEA:

128211046 128242451

OBI:

106872578

OSN:

115214765

LJP:	135465390 135474789

LAK:	106161133 106161152 106178779

LLON:

135487936 135495928

NVE:	5508573 5520220

EPA:	110253070 110253790

ATEN:

116298868 116300587

ADF:	107328641 107350082

AMIL:

114955550 114958283

MCAZ:

138018848 138060624 138060650

MFOO:

137970142 137993204

PDAM:

113674939 113675617

SPIS:

111321002 111338107

DGT:	114532402 114532739

XEN:	124437078 124442382

HMG:	100205428 100206858

HSY:	130644526 130649407

RES:	135685614 135691626

TAD:	TRIADDRAFT_19665

AQU:	100634643 100636817 100638252

MBR:	MONBRDRAFT_12342 MONBRDRAFT_33442

SRE:	PTSG_01005 PTSG_02541

DDI:	DDB_G0286735

DPP:	DICPUDRAFT_149221

DFA:

DFA_11876

ACAN:

ACA1_392390

» show all

Reference

PMID:16162816

Authors

Morita Y, Kanei-Ishii C, Nomura T, Ishii S

Title

TRAF7 sequesters c-Myb to the cytoplasm by stimulating its sumoylation.

Journal

Mol Biol Cell 16:5433-44 (2005)
DOI:10.1091/mbc.E05-08-0731

Sequence

[mmu:224619]

Reference

PMID:15001576

Authors

Xu LG, Li LY, Shu HB

Title

TRAF7 potentiates MEKK3-induced AP1 and CHOP activation and induces apoptosis.

Journal

J Biol Chem 279:17278-82 (2004)
DOI:10.1074/jbc.C400063200

Sequence

[hsa:84231]

LinkDB

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