KEGG   PATHWAY: ccan04144
Entry
ccan04144                   Pathway                                
Name
Endocytosis - Castor canadensis (American beaver)
Description
Endocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins entering through clathrin-dependent endocytosis (CDE) have sequences in their cytoplasmic domains that bind to the APs (adaptor-related protein complexes) and enable their rapid removal from the PM. In addition to APs and clathrin, there are numerous accessory proteins including dynamin. Depending on the various proteins that enter the endosome membrane, these cargoes are sorted to distinct destinations. Some cargoes, such as nutrient receptors, are recycled back to the PM. Ubiquitylated membrane proteins, such as activated growth-factor receptors, are sorted into intraluminal vesicles and eventually end up in the lysosome lumen via multivesicular endosomes (MVEs). There are distinct mechanisms of clathrin-independent endocytosis (CIE) depending upon the cargo and the cell type.
Class
Cellular Processes; Transport and catabolism
Pathway map
ccan04144  Endocytosis
ccan04144

Other DBs
GO: 0006897
Organism
Castor canadensis (American beaver) [GN:ccan]
Gene
109673990  Il2rg; cytokine receptor common subunit gamma [KO:K05070]
109674438  Snx12; sorting nexin-12 isoform X1 [KO:K17918]
109674509  Kif5c; kinesin heavy chain [KO:K10396] [EC:5.6.1.3]
109674567  [KO:K18466]
109674647  Acap1; arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X1 [KO:K12489]
109674701  [KO:K12494]
109675416  [KO:K12197]
109676704  [KO:K08291] [EC:2.7.11.16]
109677935  [KO:K12195]
109679292  [KO:K12186]
109679582  Psd3; PH and SEC7 domain-containing protein 3 isoform X1 [KO:K12494]
109680800  Arrb1; beta-arrestin-1 isoform X1 [KO:K04439]
109681154  Acap3; arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 isoform X1 [KO:K12489]
109681186  Vps45; vacuolar protein sorting-associated protein 45 [KO:K12479]
109681221  Pip5k1a; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1 [KO:K00889] [EC:2.7.1.68]
109681337  Arap3; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1 [KO:K12490]
109681403  Iqsec1; IQ motif and SEC7 domain-containing protein 1 isoform X1 [KO:K12495]
109681486  Epn3; epsin-3 isoform X1 [KO:K12471]
109681522  Tgfbr2; TGF-beta receptor type-2 [KO:K04388] [EC:2.7.11.30]
109681714  Capza1; F-actin-capping protein subunit alpha-1 [KO:K10364]
109681879  Rab11fip1; LOW QUALITY PROTEIN: rab11 family-interacting protein 1 [KO:K12484]
109682033  Wipf3; WAS/WASL-interacting protein family member 3 [KO:K19475]
109682195  Kif5b; kinesin-1 heavy chain [KO:K10396] [EC:5.6.1.3]
109682366  Vps29; vacuolar protein sorting-associated protein 29 isoform X1 [KO:K18467]
109682371  Vps35; vacuolar protein sorting-associated protein 35 [KO:K18468]
109682643  Psd4; PH and SEC7 domain-containing protein 4 isoform X1 [KO:K12494]
109682694  Cyth2; cytohesin-2 [KO:K18441]
109682712  Cyth1; cytohesin-1 isoform X1 [KO:K18441]
109682998  [KO:K06564]
109682999  [KO:K06564]
109683041  Chmp2a; charged multivesicular body protein 2a [KO:K12191]
109683092  Ldlrap1; low density lipoprotein receptor adapter protein 1 isoform X1 [KO:K12474]
109683131  [KO:K07939]
109683132  [KO:K07939]
109683429  Arpc5l; actin-related protein 2/3 complex subunit 5-like protein isoform X1 [KO:K05754]
109683536  Vps37b; vacuolar protein sorting-associated protein 37B isoform X1 [KO:K12185]
109683562  Snx6; sorting nexin-6 [KO:K17920]
109683743  Arpc3; actin-related protein 2/3 complex subunit 3 [KO:K05756]
109683757  Git2; ARF GTPase-activating protein GIT2 isoform X1 [KO:K12487]
109683762  Git1; LOW QUALITY PROTEIN: ARF GTPase-activating protein GIT1 [KO:K05737]
109683879  Ap2a1; LOW QUALITY PROTEIN: AP-2 complex subunit alpha-1 [KO:K11824]
109683985  [KO:K18462]
109683989  [KO:K18462]
109684266  [KO:K12472]
109684268  [KO:K12472]
109684417  [KO:K10364]
109684419  Capza2; F-actin-capping protein subunit alpha-2 [KO:K10364]
109684429  Smurf1; E3 ubiquitin-protein ligase SMURF1 isoform X1 [KO:K04678] [EC:2.3.2.26]
109684472  [KO:K00910] [EC:2.7.11.15]
109684604  Asap3; arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 [KO:K12488]
109684653  [KO:K12491]
109684661  [KO:K12495]
109684712  [KO:K04237]
109684714  [KO:K04237]
109684749  Pld2; LOW QUALITY PROTEIN: phospholipase D2 [KO:K01115] [EC:3.1.4.4]
109684810  [KO:K07937]
109684971  Spg20; spartin [KO:K19366]
109685027  Actr2; actin-related protein 2 isoform X1 [KO:K17260]
109685059  Arpc1b; actin-related protein 2/3 complex subunit 1B [KO:K05757]
109685067  Arpc1a; actin-related protein 2/3 complex subunit 1A [KO:K05757]
109685094  Pdgfra; LOW QUALITY PROTEIN: platelet-derived growth factor receptor alpha [KO:K04363] [EC:2.7.10.1]
109685120  Cltc; clathrin heavy chain 1 isoform X1 [KO:K04646]
109685213  Rab11fip4; LOW QUALITY PROTEIN: rab11 family-interacting protein 4 [KO:K12485]
109685223  Vps26a; LOW QUALITY PROTEIN: vacuolar protein sorting-associated protein 26A [KO:K18466]
109685512  Washc4; WASH complex subunit SWIP isoform X1 [KO:K18465]
109685621  Rab4a; ras-related protein Rab-4A [KO:K07879]
109685731  Grk4; LOW QUALITY PROTEIN: G protein-coupled receptor kinase 4 [KO:K08291] [EC:2.7.11.16]
109685760  Grk6; G protein-coupled receptor kinase 6 isoform X1 [KO:K08291] [EC:2.7.11.16]
109685768  Fgfr4; fibroblast growth factor receptor 4 isoform X1 [KO:K05095] [EC:2.7.10.1]
109685778  Cltb; clathrin light chain B [KO:K04645]
109685794  [KO:K04705]
109685795  [KO:K04705]
109685858  Chmp4a; charged multivesicular body protein 4a [KO:K12194]
109685890  Rab10; ras-related protein Rab-10 [KO:K07903]
109685893  Itch; E3 ubiquitin-protein ligase Itchy homolog [KO:K05632] [EC:2.3.2.26]
109686059  Rnf41; E3 ubiquitin-protein ligase NRDP1 [KO:K11981] [EC:2.3.2.27]
109686091  [KO:K11981] [EC:2.3.2.27]
109686156  Kif5a; kinesin heavy chain isoform X1 [KO:K10396] [EC:5.6.1.3]
109686253  Agap2; arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 isoform X1 [KO:K17848]
109686509  Chmp5; charged multivesicular body protein 5 [KO:K12198]
109686516  [KO:K11248]
109686517  [KO:K11248]
109686551  Arap1; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 isoform X1 [KO:K18439]
109686771  Pip5kl1; phosphatidylinositol 4-phosphate 5-kinase-like protein 1 [KO:K13712] [EC:2.7.1.68]
109686794  Dnm1; dynamin-1 isoform X1 [KO:K01528] [EC:3.6.5.5]
109686851  Clta; clathrin light chain A isoform X1 [KO:K04644]
109686924  Grk1; LOW QUALITY PROTEIN: rhodopsin kinase [KO:K00909] [EC:2.7.11.14]
109686964  Snx3; sorting nexin-3 [KO:K17918]
109686996  Arpc4; actin-related protein 2/3 complex subunit 4 [KO:K05755]
109687131  Pard6g; partitioning defective 6 homolog gamma [KO:K06093]
109687170  Ehd1; EH domain-containing protein 1 [KO:K12483]
109687279  [KO:K06751]
109687282  [KO:K06751]
109687284  [KO:K06751]
109687287  [KO:K06751]
109687339  Vps25; vacuolar protein-sorting-associated protein 25 [KO:K12189]
109687478  Capzb; F-actin-capping protein subunit beta isoform X1 [KO:K10365]
109687530  [KO:K05087] [EC:2.7.10.1]
109687659  [KO:K10054] [EC:2.3.2.-]
109687681  Vps37c; vacuolar protein sorting-associated protein 37C isoform X1 [KO:K12185]
109687813  Sh3gl1; endophilin-A2 [KO:K11247]
109688128  Washc5; LOW QUALITY PROTEIN: WASH complex subunit strumpellin [KO:K18464]
109688141  Stambp; STAM-binding protein isoform X1 [KO:K11866] [EC:3.4.19.12]
109688299  Spg21; maspardin isoform X1 [KO:K19367]
109688304  [KO:K19367]
109688330  Dab2; LOW QUALITY PROTEIN: disabled homolog 2 [KO:K12475]
109688446  Rufy1; RUN and FYVE domain-containing protein 1 [KO:K12482]
109688571  Asap1; arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X1 [KO:K12488]
109688678  [KO:K12200]
109688752  Smap1; stromal membrane-associated protein 1 isoform X1 [KO:K12486]
109688805  [KO:K04679]
109688820  Actr3b; actin-related protein 3B isoform X1 [KO:K18584]
109689037  [KO:K23484]
109689056  Rab8a; ras-related protein Rab-8A [KO:K07901]
109689063  Eps15l1; epidermal growth factor receptor substrate 15-like 1 isoform X1 [KO:K12472]
109689069  [KO:K23484]
109689181  Psd2; PH and SEC7 domain-containing protein 2 [KO:K12494]
109689401  Rabep1; rab GTPase-binding effector protein 1 isoform X1 [KO:K12480]
109689438  Wasl; neural Wiskott-Aldrich syndrome protein [KO:K23612]
109689439  [KO:K23612]
109689570  [KO:K03283]
109689571  [KO:K03283]
109689572  [KO:K03283]
109689700  Chmp7; charged multivesicular body protein 7 [KO:K15053]
109689838  Wipf1; WAS/WASL-interacting protein family member 1 isoform X1 [KO:K19475]
109689844  Chmp6; charged multivesicular body protein 6 [KO:K12195]
109689878  Cav1; caveolin-1 [KO:K06278]
109689881  Cav2; caveolin-2 isoform X1 [KO:K12958]
109690296  Arpc5; actin-related protein 2/3 complex subunit 5 [KO:K05754]
109690375  [KO:K06751]
109690377  [KO:K06751]
109690388  [KO:K04513]
109690530  Arfgef2; brefeldin A-inhibited guanine nucleotide-exchange protein 2 isoform X1 [KO:K18442]
109690605  Rab22a; ras-related protein Rab-22A [KO:K07891]
109690611  Il2ra; LOW QUALITY PROTEIN: interleukin-2 receptor subunit alpha [KO:K05068]
109690706  Grk2; beta-adrenergic receptor kinase 1 isoform X1 [KO:K00910] [EC:2.7.11.15]
109690761  Chmp4b; charged multivesicular body protein 4b [KO:K12194]
109690907  Nedd4l; E3 ubiquitin-protein ligase NEDD4-like isoform X1 [KO:K13305] [EC:2.3.2.26]
109691077  Ap2s1; AP-2 complex subunit sigma [KO:K11827]
109691182  Vps28; vacuolar protein sorting-associated protein 28 homolog isoform X1 [KO:K12184]
109691271  Pard6a; partitioning defective 6 homolog alpha isoform X1 [KO:K06093]
109691302  Psd; PH and SEC7 domain-containing protein 1 isoform X1 [KO:K12494]
109691305  Gbf1; Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 isoform X1 [KO:K18443]
109691424  Tgfbr1; TGF-beta receptor type-1 [KO:K04674] [EC:2.7.11.30]
109691439  Prkcz; protein kinase C zeta type isoform X1 [KO:K18952] [EC:2.7.11.13]
109691578  Smap2; stromal membrane-associated protein 2 isoform X1 [KO:K12486]
109691649  Fgfr2; fibroblast growth factor receptor 2 isoform X1 [KO:K05093] [EC:2.7.10.1]
109692171  Chmp2b; charged multivesicular body protein 2b [KO:K12192]
109692362  Cblc; E3 ubiquitin-protein ligase CBL-C [KO:K22518] [EC:2.3.2.27]
109692527  Ldlr; LOW QUALITY PROTEIN: low-density lipoprotein receptor [KO:K12473]
109692646  Rab5a; ras-related protein Rab-5A [KO:K07887]
109692754  Chmp1a; charged multivesicular body protein 1a isoform X1 [KO:K12197]
109692778  Acap2; arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 isoform X1 [KO:K12489]
109692845  Arfgap1; ADP-ribosylation factor GTPase-activating protein 1 isoform X1 [KO:K12492]
109692921  Cyth3; cytohesin-3 [KO:K18441]
109693007  [KO:K13649]
109693045  Snx1; sorting nexin-1 isoform X1 [KO:K17917]
109693114  Arfgap3; ADP-ribosylation factor GTPase-activating protein 3 isoform X1 [KO:K12493]
109693131  Ehd4; EH domain-containing protein 4 [KO:K12477]
109693160  Epn1; epsin-1 [KO:K12471]
109693191  Arf6; ADP-ribosylation factor 6 [KO:K07941]
109693333  Mdm2; E3 ubiquitin-protein ligase Mdm2 [KO:K06643] [EC:2.3.2.27]
109693452  Sh3glb2; endophilin-B2 isoform X1 [KO:K21269]
109693485  Ap2b1; AP-2 complex subunit beta isoform X1 [KO:K11825]
109693503  [KO:K03283]
109693564  Traf6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
109693692  Pard6b; LOW QUALITY PROTEIN: partitioning defective 6 homolog beta [KO:K06093]
109693753  Egfr; epidermal growth factor receptor isoform X1 [KO:K04361] [EC:2.7.10.1]
109693755  Vps4b; vacuolar protein sorting-associated protein 4B [KO:K12196]
109693768  Vps4a; vacuolar protein sorting-associated protein 4A isoform X1 [KO:K12196]
109693979  Rbsn; rabenosyn-5 [KO:K12481]
109694100  Ap2m1; AP-2 complex subunit mu isoform X1 [KO:K11826]
109694280  Ist1; IST1 homolog isoform X1 [KO:K19476]
109694404  Snx2; sorting nexin-2 isoform X1 [KO:K17917]
109694406  Zfyve16; zinc finger FYVE domain-containing protein 16 [KO:K04679]
109694414  Wipf2; WAS/WASL-interacting protein family member 2 isoform X1 [KO:K19475]
109694439  Agap3; arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform X1 [KO:K12491]
109694497  Tfrc; transferrin receptor protein 1 isoform X1 [KO:K06503]
109694583  Sh3gl3; endophilin-A3 isoform X1 [KO:K11247]
109694617  Iqsec3; LOW QUALITY PROTEIN: IQ motif and SEC7 domain-containing protein 3 [KO:K12495]
109694639  Rab11fip3; rab11 family-interacting protein 3 isoform X1 [KO:K12485]
109694642  Chmp4c; charged multivesicular body protein 4c [KO:K24782]
109694665  [KO:K18584]
109694743  Pld1; phospholipase D1 [KO:K01115] [EC:3.1.4.4]
109694817  Arf3; ADP-ribosylation factor 3 [KO:K07938]
109694921  Cdc42; cell division control protein 42 homolog [KO:K04393]
109695016  Fgfr3; fibroblast growth factor receptor 3 isoform X1 [KO:K05094] [EC:2.7.10.1]
109695579  [KO:K05632] [EC:2.3.2.26]
109695587  Smurf2; E3 ubiquitin-protein ligase SMURF2 [KO:K04678] [EC:2.3.2.26]
109695609  Cxcr4; C-X-C chemokine receptor type 4 [KO:K04189]
109695622  Mvb12a; LOW QUALITY PROTEIN: multivesicular body subunit 12A [KO:K12186]
109695712  Vps36; vacuolar protein-sorting-associated protein 36 isoform X1 [KO:K12190]
109695774  Rab5c; ras-related protein Rab-5C [KO:K07889]
109695937  Asap2; arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 isoform X1 [KO:K12488]
109696086  Chmp1b; charged multivesicular body protein 1b [KO:K12197]
109696147  Rab35; ras-related protein Rab-35 isoform X1 [KO:K07876]
109696194  Arfgap2; ADP-ribosylation factor GTPase-activating protein 2 isoform X1 [KO:K12493]
109696210  Wwp1; NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X1 [KO:K05633] [EC:2.3.2.26]
109696224  Cbl; E3 ubiquitin-protein ligase CBL isoform X1 [KO:K04707] [EC:2.3.2.27]
109696360  Rab11fip5; LOW QUALITY PROTEIN: rab11 family-interacting protein 5 [KO:K12484]
109696446  Snx5; sorting nexin-5 [KO:K17920]
109696482  Rab7a; ras-related protein Rab-7a [KO:K07897]
109696490  [KO:K04180]
109696541  Ehd2; EH domain-containing protein 2 [KO:K12469]
109696894  Tsg101; tumor susceptibility gene 101 protein [KO:K12183]
109697105  Rab11a; ras-related protein Rab-11A [KO:K07904]
109697110  Washc1; LOW QUALITY PROTEIN: WAS protein family homolog 1 [KO:K18461]
109697400  Stam; signal transducing adapter molecule 1 isoform X1 [KO:K04705]
109697447  Arrb2; beta-arrestin-2 isoform X1 [KO:K04439]
109697571  Pip5k1c; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [KO:K00889] [EC:2.7.1.68]
109697638  Vps37d; vacuolar protein sorting-associated protein 37D [KO:K12185]
109697731  Amph; amphiphysin [KO:K12562]
109697755  Hspa8; heat shock cognate 71 kDa protein [KO:K03283]
109697844  Rhoa; transforming protein RhoA [KO:K04513]
109697912  Cav3; caveolin-3 [KO:K12959]
109698041  Vps37a; vacuolar protein sorting-associated protein 37A isoform X1 [KO:K12185]
109698042  Hras; GTPase HRas isoform X1 [KO:K02833]
109698154  Ap2a2; AP-2 complex subunit alpha-2 isoform X1 [KO:K11824]
109698249  Cyth4; cytohesin-4 isoform X1 [KO:K18441]
109698250  Il2rb; interleukin-2 receptor subunit beta isoform X1 [KO:K05069]
109698438  Rab11b; ras-related protein Rab-11B [KO:K07905]
109698460  [KO:K12478]
109698573  Rab5b; ras-related protein Rab-5B [KO:K07888]
109698810  Vps26b; vacuolar protein sorting-associated protein 26B [KO:K18466]
109698917  Rab11fip2; rab11 family-interacting protein 2 isoform X1 [KO:K12484]
109699003  Cblb; E3 ubiquitin-protein ligase CBL-B isoform X1 [KO:K22517] [EC:2.3.2.27]
109699110  Bin1; myc box-dependent-interacting protein 1 isoform X1 [KO:K12562]
109699210  Arpc2; actin-related protein 2/3 complex subunit 2 [KO:K05758]
109699259  Zfyve27; protrudin isoform X1 [KO:K19368]
109699268  Arfgef1; brefeldin A-inhibited guanine nucleotide-exchange protein 1 isoform X1 [KO:K18442]
109699301  [KO:K18584]
109699321  Dnajc6; putative tyrosine-protein phosphatase auxilin isoform X1 [KO:K09526]
109699475  Snx4; sorting nexin-4 [KO:K17919]
109699715  Epn2; epsin-2 isoform X1 [KO:K12471]
109699743  Grk7; LOW QUALITY PROTEIN: rhodopsin kinase [KO:K00909] [EC:2.7.11.14]
109700210  Prkci; protein kinase C iota type isoform X1 [KO:K06069] [EC:2.7.11.13]
109700244  Arf1; ADP-ribosylation factor 1 [KO:K07937]
109700276  Usp8; ubiquitin carboxyl-terminal hydrolase 8 isoform X1 [KO:K11839] [EC:3.4.19.12]
109700302  [KO:K04500]
109700661  Washc3; WASH complex subunit CCDC53 isoform X1 [KO:K18463]
109700662  [KO:K10591] [EC:2.3.2.26]
109700779  Vta1; vacuolar protein sorting-associated protein VTA1 homolog [KO:K12199]
109700825  Grk5; G protein-coupled receptor kinase 5 [KO:K08291] [EC:2.7.11.16]
109700906  [KO:K06751]
109701045  Capza3; LOW QUALITY PROTEIN: F-actin-capping protein subunit alpha-3 [KO:K10364]
109701141  Snf8; vacuolar-sorting protein SNF8 [KO:K12188]
109701210  Rufy2; RUN and FYVE domain-containing protein 2 isoform X1 [KO:K12482]
109701329  Rab31; ras-related protein Rab-31 isoform X1 [KO:K07891]
109701375  Grk3; LOW QUALITY PROTEIN: beta-adrenergic receptor kinase 2 [KO:K00910] [EC:2.7.11.15]
109701475  Arf5; ADP-ribosylation factor 5 [KO:K07940]
109701514  Smad3; mothers against decapentaplegic homolog 3 isoform X1 [KO:K23605]
109701711  Ehd3; EH domain-containing protein 3 isoform X1 [KO:K12476]
109702274  [KO:K04363] [EC:2.7.10.1]
109702281  [KO:K05704] [EC:2.7.10.2]
109702480  Hgs; hepatocyte growth factor-regulated tyrosine kinase substrate isoform X1 [KO:K12182]
109703335  [KO:K07887]
Compound
C00035  GDP
C00044  GTP
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
Reference
PMID:19007773
  Authors
Acconcia F, Sigismund S, Polo S
  Title
Ubiquitin in trafficking: the network at work.
  Journal
Exp Cell Res 315:1610-8 (2009)
DOI:10.1016/j.yexcr.2008.10.014
Reference
PMID:18647649
  Authors
Donaldson JG, Porat-Shliom N, Cohen LA
  Title
Clathrin-independent endocytosis: a unique platform for cell signaling and PM remodeling.
  Journal
Cell Signal 21:1-6 (2009)
DOI:10.1016/j.cellsig.2008.06.020
Reference
PMID:15261671
  Authors
Sorkin A
  Title
Cargo recognition during clathrin-mediated endocytosis: a team effort.
  Journal
Curr Opin Cell Biol 16:392-9 (2004)
DOI:10.1016/j.ceb.2004.06.001
Reference
PMID:19325624
  Authors
Raiborg C, Stenmark H
  Title
The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins.
  Journal
Nature 458:445-52 (2009)
DOI:10.1038/nature07961
Reference
PMID:20110990
  Authors
Scita G, Di Fiore PP
  Title
The endocytic matrix.
  Journal
Nature 463:464-73 (2010)
DOI:10.1038/nature08910
Reference
PMID:15687999
  Authors
Le Roy C, Wrana JL
  Title
Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling.
  Journal
Nat Rev Mol Cell Biol 6:112-26 (2005)
DOI:10.1038/nrm1571
Reference
PMID:19924646
  Authors
Jovic M, Sharma M, Rahajeng J, Caplan S
  Title
The early endosome: a busy sorting station for proteins at the crossroads.
  Journal
Histol Histopathol 25:99-112 (2010)
DOI:10.14670/HH-25.99
Reference
PMID:16203612
  Authors
Pietiainen VM, Marjomaki V, Heino J, Hyypia T
  Title
Viral entry, lipid rafts and caveosomes.
  Journal
Ann Med 37:394-403 (2005)
DOI:10.1080/07853890510011976
Reference
PMID:19696797
  Authors
Grant BD, Donaldson JG
  Title
Pathways and mechanisms of endocytic recycling.
  Journal
Nat Rev Mol Cell Biol 10:597-608 (2009)
DOI:10.1038/nrm2755
Reference
PMID:22193161
  Authors
Cullen PJ, Korswagen HC
  Title
Sorting nexins provide diversity for retromer-dependent trafficking events.
  Journal
Nat Cell Biol 14:29-37 (2012)
DOI:10.1038/ncb2374
Related
pathway
ccan04060  Cytokine-cytokine receptor interaction
ccan04070  Phosphatidylinositol signaling system
ccan04130  SNARE interactions in vesicular transport
ccan04142  Lysosome
ccan04350  TGF-beta signaling pathway
KO pathway
ko04144   

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