KEGG   PATHWAY: tdc04141
Entry
tdc04141                    Pathway                                
Name
Protein processing in endoplasmic reticulum - Triticum dicoccoides (wild emmer wheat)
Description
The endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylated. Correctly folded proteins are packaged into transport vesicles that shuttle them to the Golgi complex. Misfolded proteins are retained within the ER lumen in complex with molecular chaperones. Proteins that are terminally misfolded bind to BiP and are directed toward degradation through the proteasome in a process called ER-associated degradation (ERAD). Accumulation of misfolded proteins in the ER causes ER stress and activates a signaling pathway called the unfolded protein response (UPR). In certain severe situations, however, the protective mechanisms activated by the UPR are not sufficient to restore normal ER function and cells die by apoptosis.
Class
Genetic Information Processing; Folding, sorting and degradation
Pathway map
tdc04141  Protein processing in endoplasmic reticulum
tdc04141

Other DBs
GO: 0030433 0034976
Organism
Triticum dicoccoides (wild emmer wheat) [GN:tdc]
Gene
119309781  protein transport protein Sec61 subunit alpha-like [KO:K10956]
119275698  protein transport protein Sec61 subunit alpha-like [KO:K10956]
119296289  protein transport protein Sec61 subunit alpha-like isoform X1 [KO:K10956]
119296290  protein transport protein Sec61 subunit alpha-like isoform X1 [KO:K10956]
119296292  protein transport protein Sec61 subunit alpha-like [KO:K10956]
119299722  protein transport protein Sec61 subunit alpha-like [KO:K10956]
119284911  protein transport protein Sec61 subunit alpha-like [KO:K10956]
119301064  preprotein translocase subunit SECY, chloroplastic-like [KO:K10956]
119301348  protein transport protein Sec61 subunit alpha-like [KO:K10956]
119340149  protein transport protein Sec61 subunit alpha-like [KO:K10956]
119291224  protein transport protein Sec61 subunit alpha-like [KO:K10956]
119308589  preprotein translocase subunit SECY, chloroplastic-like [KO:K10956]
119308915  protein transport protein Sec61 subunit alpha-like [KO:K10956]
119276086  protein transport protein Sec61 subunit beta-like [KO:K09481]
119295648  protein transport protein Sec61 subunit beta-like [KO:K09481]
119296819  protein transport protein Sec61 subunit beta-like [KO:K09481]
119301022  protein transport protein Sec61 subunit beta-like [KO:K09481]
119268215  protein transport protein Sec61 subunit beta-like [KO:K09481]
119286166  protein transport protein Sec61 subunit beta-like [KO:K09481]
119307063  protein transport protein Sec61 subunit beta-like [KO:K09481]
119308537  protein transport protein Sec61 subunit beta-like [KO:K09481]
119344884  protein transport protein Sec61 subunit gamma-like [KO:K07342]
119327583  protein transport protein Sec61 subunit gamma-like [KO:K07342]
119327888  protein transport protein Sec61 subunit gamma-like [KO:K07342]
119294141  protein transport protein Sec61 subunit gamma-like [KO:K07342]
119314948  protein transport protein Sec61 subunit gamma-like [KO:K07342]
119366717  protein transport protein Sec61 subunit gamma-like [KO:K07342]
119280818  protein transport protein Sec61 subunit gamma-like [KO:K07342]
119297645  protein transport protein Sec61 subunit gamma-like [KO:K07342]
119316300  protein transport protein Sec61 subunit gamma-like [KO:K07342]
119332372  protein transport protein Sec61 subunit gamma [KO:K07342]
119368990  protein transport protein Sec61 subunit gamma-like [KO:K07342]
119335906  protein transport protein Sec61 subunit gamma-like [KO:K07342]
119321789  protein transport protein Sec61 subunit gamma-like [KO:K07342]
119322750  protein transport protein Sec61 subunit gamma-like [KO:K07342]
119323146  protein transport protein Sec61 subunit gamma-like [KO:K07342]
119358759  protein transport protein Sec61 subunit gamma-like [KO:K07342]
119359586  protein transport protein Sec61 subunit gamma-like [KO:K07342]
119304106  protein transport protein Sec61 subunit gamma-like [KO:K07342]
119340430  protein transport protein Sec61 subunit gamma [KO:K07342]
119316927  uncharacterized protein LOC119316927 [KO:K12275]
119322567  uncharacterized protein LOC119322567 [KO:K12275]
119363991  dnaJ protein ERDJ2 [KO:K09540]
119354862  dnaJ protein ERDJ2-like [KO:K09540]
119291843  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1A [KO:K12666]
119346756  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1B [KO:K12666]
119303958  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1A-like [KO:K12666]
119278048  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2-like [KO:K12667]
119270020  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 [KO:K12667]
119329673  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 [KO:K12668]
119330444  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD2 [KO:K12668]
119340141  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD2-like [KO:K12668]
119288193  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD2-like [KO:K12668]
119340468  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD2-like isoform X1 [KO:K12668]
119328590  dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit [KO:K12670]
119340511  dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit-like [KO:K12670]
119276827  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A-like isoform X1 [KO:K07151] [EC:2.4.99.18]
119349032  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A [KO:K07151] [EC:2.4.99.18]
119366373  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B-like [KO:K07151] [EC:2.4.99.18]
119357095  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B [KO:K07151] [EC:2.4.99.18]
119268871  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A-like [KO:K07151] [EC:2.4.99.18]
119287360  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A-like [KO:K07151] [EC:2.4.99.18]
119336542  probable dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3 [KO:K19478]
119328847  probable dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3 [KO:K19478]
119331230  oligosaccharyltransferase complex subunit ostc-like [KO:K26501]
119331649  transmembrane protein 258-like [KO:K26502]
119339994  transmembrane protein 258-like [KO:K26502]
119322634  transmembrane protein 258-like isoform X1 [KO:K26502]
119316681  transmembrane protein 258-like isoform X1 [KO:K26502]
119278174  mannosyl-oligosaccharide glucosidase GCS1-like [KO:K01228] [EC:3.2.1.106]
119270373  alpha-glucosidase 2-like [KO:K01228] [EC:3.2.1.106]
119317620  heat shock 70 kDa protein 17-like [KO:K09486]
119324439  heat shock 70 kDa protein 17-like [KO:K09486]
119343781  heat shock 70 kDa protein BIP4-like [KO:K09490] [EC:3.6.4.10]
119347642  heat shock 70 kDa protein BIP4-like [KO:K09490] [EC:3.6.4.10]
119350642  heat shock 70 kDa protein BIP4-like [KO:K09490] [EC:3.6.4.10]
119352423  heat shock 70 kDa protein BIP5-like [KO:K09490] [EC:3.6.4.10]
119352424  heat shock 70 kDa protein BIP5-like [KO:K09490] [EC:3.6.4.10]
119352425  heat shock 70 kDa protein BIP5-like [KO:K09490] [EC:3.6.4.10]
119352428  heat shock 70 kDa protein BIP5-like [KO:K09490] [EC:3.6.4.10]
119352429  heat shock 70 kDa protein BIP4-like [KO:K09490] [EC:3.6.4.10]
119352430  heat shock 70 kDa protein BIP5-like [KO:K09490] [EC:3.6.4.10]
119352431  heat shock 70 kDa protein BIP5-like [KO:K09490] [EC:3.6.4.10]
119353300  heat shock 70 kDa protein BIP5-like [KO:K09490] [EC:3.6.4.10]
119319558  luminal-binding protein 2 [KO:K09490] [EC:3.6.4.10]
119320434  luminal-binding protein 2 [KO:K09490] [EC:3.6.4.10]
119357162  heat shock 70 kDa protein BIP5-like [KO:K09490] [EC:3.6.4.10]
119339282  luminal-binding protein 4-like [KO:K09490] [EC:3.6.4.10]
119340064  heat shock 70 kDa protein BIP5-like [KO:K09490] [EC:3.6.4.10]
119305877  heat shock 70 kDa protein BIP5-like [KO:K09490] [EC:3.6.4.10]
119340592  heat shock 70 kDa protein BIP5-like [KO:K09490] [EC:3.6.4.10]
119362431  heat shock 70 kDa protein BIP5-like [KO:K09490] [EC:3.6.4.10]
119294430  heat shock 70 kDa protein BIP2-like [KO:K09490] [EC:3.6.4.10]
119341958  luminal-binding protein-like [KO:K09490] [EC:3.6.4.10]
119327081  dnaJ protein ERDJ3B-like [KO:K09517]
119367281  dnaJ protein ERDJ3B [KO:K09517]
119343759  dnaJ protein P58IPK homolog B-like isoform X1 [KO:K09523]
119344649  dnaJ protein P58IPK homolog B-like isoform X1 [KO:K09523]
119310397  heat shock protein 90-5, chloroplastic-like [KO:K09487]
119328120  endoplasmin homolog isoform X1 [KO:K09487]
119300617  heat shock protein 90-6, mitochondrial-like [KO:K09487]
119335977  endoplasmin homolog isoform X1 [KO:K09487]
119301921  heat shock protein 90-5, chloroplastic-like [KO:K09487]
119307947  heat shock protein 90-6, mitochondrial-like [KO:K09487]
119284945  probable glucan 1,3-alpha-glucosidase [KO:K05546] [EC:3.2.1.207]
119291193  probable glucan 1,3-alpha-glucosidase [KO:K05546] [EC:3.2.1.207]
119275865  glucosidase 2 subunit beta-like [KO:K08288]
119267995  glucosidase 2 subunit beta-like [KO:K08288]
119315076  calnexin homolog [KO:K08054]
119315077  calnexin homolog [KO:K08054]
119321757  calnexin homolog [KO:K08054]
119322836  calnexin homolog [KO:K08054]
119366285  calreticulin isoform X1 [KO:K08057]
119277894  calreticulin-3-like [KO:K08057]
119357020  calreticulin-like isoform X1 [KO:K08057]
119269882  calreticulin-3-like [KO:K08057]
119306668  calreticulin-like [KO:K08057]
119289491  calreticulin-like [KO:K08057]
119365454  mannosyl-oligosaccharide 1,2-alpha-mannosidase MNS1-like isoform X1 [KO:K01230] [EC:3.2.1.113]
119356278  mannosyl-oligosaccharide 1,2-alpha-mannosidase MNS1-like isoform X1 [KO:K01230] [EC:3.2.1.113]
119329569  mannosyl-oligosaccharide 1,2-alpha-mannosidase MNS3-like isoform X1 [KO:K23741] [EC:3.2.1.209]
119368635  mannosyl-oligosaccharide 1,2-alpha-mannosidase MNS3-like isoform X1 [KO:K23741] [EC:3.2.1.209]
119330379  SEC12-like protein 1 [KO:K14003]
119330616  SEC12-like protein 2 [KO:K14003]
119295926  SEC12-like protein 2 [KO:K14003]
119300245  SEC12-like protein 1 [KO:K14003]
119285952  SEC12-like protein 2 isoform X1 [KO:K14003]
119338140  SEC12-like protein 1 [KO:K14003]
119306474  SEC12-like protein 1 [KO:K14003]
119341417  SEC12-like protein 2 [KO:K14003]
119275717  GTP-binding protein SAR1A-like [KO:K07953] [EC:3.6.5.-]
119275912  GTP-binding protein SAR1A-like [KO:K07953] [EC:3.6.5.-]
119331788  GTP-binding protein SAR1A-like [KO:K07953] [EC:3.6.5.-]
119300081  GTP-binding protein SAR1A [KO:K07953] [EC:3.6.5.-]
119267838  GTP-binding protein SAR1A-like [KO:K07953] [EC:3.6.5.-]
119268065  GTP-binding protein SAR1A-like [KO:K07953] [EC:3.6.5.-]
119340488  GTP-binding protein SAR1A-like [KO:K07953] [EC:3.6.5.-]
119340549  GTP-binding protein SAR1A-like [KO:K07953] [EC:3.6.5.-]
119307823  GTP-binding protein SAR1A-like [KO:K07953] [EC:3.6.5.-]
119312571  protein transport protein SEC13 homolog B-like [KO:K14004]
119365905  protein transport protein SEC13 homolog B-like [KO:K14004]
119318329  protein transport protein SEC13 homolog B-like [KO:K14004]
119356683  protein transport protein SEC13 homolog B-like [KO:K14004]
119303874  protein transport protein SEC13 homolog B-like [KO:K14004]
119353500  protein transport protein SEC31 homolog B-like isoform X1 [KO:K14005]
119362671  protein transport protein SEC31 homolog B-like [KO:K14005]
119310135  protein transport protein SEC23-like [KO:K14006]
119311769  protein transport protein sec23-1-like [KO:K14006]
119295175  protein transport protein SEC23-like [KO:K14006]
119295960  protein transport protein SEC23-like [KO:K14006]
119301851  protein transport protein SEC23-like [KO:K14006]
119285861  protein transport protein SEC23-like [KO:K14006]
119286588  protein transport protein SEC23-like [KO:K14006]
119303092  protein transport protein sec23-1-like [KO:K14006]
119323476  protein transport protein SEC23-like isoform X1 [KO:K14006]
119295359  protein transport protein Sec24-like CEF [KO:K14007]
119352689  protein transport protein Sec24-like At3g07100 [KO:K14007]
119300674  protein transport protein Sec24-like CEF [KO:K14007]
119286355  protein transport protein Sec24-like CEF [KO:K14007]
119361698  protein transport protein Sec24-like At3g07100 [KO:K14007]
119268820  UDP-glucose:glycoprotein glucosyltransferase-like isoform X1 [KO:K11718] [EC:2.4.1.-]
119321153  UDP-glucose:glycoprotein glucosyltransferase-like isoform X1 [KO:K11718] [EC:2.4.1.-]
119317891  alpha-mannosidase I MNS5-like [KO:K10084]
119324161  alpha-mannosidase I MNS5-like [KO:K10084]
119277168  alpha-mannosidase I MNS4-like isoform X1 [KO:K10085]
119269171  alpha-mannosidase I MNS4-like isoform X1 [KO:K10085]
119364308  protein disulfide isomerase-like 5-2 [KO:K09580] [EC:5.3.4.1]
119364331  protein disulfide isomerase-like 1-2 [KO:K09580] [EC:5.3.4.1]
119292454  uncharacterized protein LOC119292454 [KO:K09580] [EC:5.3.4.1]
119295313  protein disulfide-isomerase-like [KO:K09580] [EC:5.3.4.1]
119330213  protein disulfide isomerase-like 1-5 [KO:K09580] [EC:5.3.4.1]
119280087  protein disulfide isomerase-like 1-4 [KO:K09580] [EC:5.3.4.1]
119317213  protein disulfide isomerase-like 5-3 [KO:K09580] [EC:5.3.4.1]
119355181  protein disulfide isomerase-like 5-2 [KO:K09580] [EC:5.3.4.1]
119319155  protein disulfide isomerase-like 1-4 [KO:K09580] [EC:5.3.4.1]
119319161  protein disulfide isomerase-like 1-4 isoform X1 [KO:K09580] [EC:5.3.4.1]
119286459  protein disulfide-isomerase [KO:K09580] [EC:5.3.4.1]
119338014  protein disulfide isomerase-like 1-5 [KO:K09580] [EC:5.3.4.1]
119322889  protein disulfide isomerase-like 5-3 [KO:K09580] [EC:5.3.4.1]
119323356  protein disulfide isomerase-like 1-4 [KO:K09580] [EC:5.3.4.1]
119309911  protein disulfide isomerase-like 2-3 [KO:K09584] [EC:5.3.4.1]
119326799  protein disulfide isomerase-like 2-1 [KO:K09584] [EC:5.3.4.1]
119367373  protein disulfide isomerase-like 2-1 [KO:K09584] [EC:5.3.4.1]
119301785  protein disulfide isomerase-like 2-3 [KO:K09584] [EC:5.3.4.1]
119294977  endoplasmic reticulum oxidoreductin-1-like [KO:K10950] [EC:1.8.4.-]
119329835  protein OS-9 homolog [KO:K10088]
119337057  protein OS-9 homolog [KO:K10088]
119328773  translocon-associated protein subunit alpha-like [KO:K13249]
119336161  translocon-associated protein subunit alpha-like [KO:K13249]
119267024  translocon-associated protein subunit beta-like [KO:K13250]
119274835  translocon-associated protein subunit beta-like [KO:K13250]
119342820  uncharacterized protein LOC119342820 [KO:K14009]
119329640  B-cell receptor-associated protein 31-like [KO:K14009]
119312850  B-cell receptor-associated protein 31-like [KO:K14009]
119278743  uncharacterized protein LOC119278743 [KO:K14009]
119332152  B-cell receptor-associated protein 31-like [KO:K14009]
119337994  B-cell receptor-associated protein 31-like [KO:K14009]
119287400  B-cell receptor-associated protein 31-like [KO:K14009]
119341073  B-cell receptor-associated protein 31-like [KO:K14009]
119329041  derlin-1-like isoform X1 [KO:K13989]
119312922  derlin-2 [KO:K13989]
119368189  derlin-1 [KO:K13989]
119287337  derlin-2-like [KO:K13989]
119295061  plant UBX domain-containing protein 11-like [KO:K24348]
119286686  plant UBX domain-containing protein 11-like [KO:K24348]
119309349  plant UBX domain-containing protein 2-like [KO:K14011]
119301516  plant UBX domain-containing protein 2-like [KO:K14011]
119364532  plant UBX domain-containing protein 4-like [KO:K14012]
119329090  plant UBX domain-containing protein 4-like [KO:K14012]
119355409  plant UBX domain-containing protein 4-like [KO:K14012]
119337181  plant UBX domain-containing protein 4-like [KO:K14012]
119309910  cell division cycle protein 48 homolog [KO:K13525]
119346734  cell division cycle protein 48 homolog [KO:K13525]
119346744  cell division control protein 48 homolog D-like [KO:K13525]
119347435  cell division cycle protein 48 homolog [KO:K13525]
119276590  cell division control protein 48 homolog E-like [KO:K13525]
119295084  cell division control protein 48 homolog E-like [KO:K13525]
119350848  cell division cycle protein 48 homolog [KO:K13525]
119279453  cell division control protein 48 homolog D-like [KO:K13525]
119353363  cell division control protein 48 homolog A-like [KO:K13525]
119281046  cell division control protein 48 homolog D-like [KO:K13525]
119281109  cell division control protein 48 homolog D-like [KO:K13525]
119281113  cell division control protein 48 homolog D-like [KO:K13525]
119281117  cell division control protein 48 homolog D-like [KO:K13525]
119281118  cell division cycle protein 48 homolog [KO:K13525]
119281122  cell division cycle protein 48 homolog [KO:K13525]
119281125  cell division control protein 48 homolog D-like [KO:K13525]
119281126  cell division cycle protein 48 homolog [KO:K13525]
119284736  cell division control protein 48 homolog E-like [KO:K13525]
119284737  cell division control protein 48 homolog E [KO:K13525]
119271397  cell division control protein 48 homolog D-like [KO:K13525]
119305957  cell division cycle protein 48 homolog [KO:K13525]
119305958  cell division cycle protein 48 homolog [KO:K13525]
119305959  cell division cycle protein 48 homolog [KO:K13525]
119306376  cell division control protein 48 homolog E-like [KO:K13525]
119306400  cell division control protein 48 homolog E-like [KO:K13525]
119306411  cell division control protein 48 homolog E-like [KO:K13525]
119307109  cell division cycle protein 48 homolog [KO:K13525]
119272850  cell division control protein 48 homolog E-like [KO:K13525]
119291420  cell division control protein 48 homolog E-like [KO:K13525]
119291421  cell division control protein 48 homolog E-like [KO:K13525]
119315387  NPL4-like protein [KO:K14015]
119322728  NPL4-like protein [KO:K14015]
119365133  ubiquitin fusion degradation protein 1 homolog isoform X1 [KO:K14016]
119279273  ubiquitin recognition factor in ER-associated degradation protein 1-like [KO:K14016]
119279274  uncharacterized protein LOC119279274 [KO:K14016]
119279275  ubiquitin recognition factor in ER-associated degradation protein 1-like [KO:K14016]
119279276  uncharacterized protein LOC119279276 [KO:K14016]
119316252  ubiquitin fusion degradation protein 1 homolog [KO:K14016]
119355999  ubiquitin fusion degradation protein 1 homolog [KO:K14016]
119322988  ubiquitin fusion degradation protein 1 homolog isoform X1 [KO:K14016]
119271848  ubiquitin recognition factor in ER-associated degradation protein 1-like [KO:K14016]
119271849  ubiquitin recognition factor in ER-associated degradation protein 1-like [KO:K14016]
119347443  heat shock 70 kDa protein 4 [KO:K03283]
119364800  heat shock cognate 70 kDa protein 2-like [KO:K03283]
119277548  heat shock cognate 70 kDa protein-like [KO:K03283]
119312522  heat shock cognate 70 kDa protein 2-like [KO:K03283]
119330397  stromal 70 kDa heat shock-related protein, chloroplastic-like [KO:K03283]
119295723  heat shock cognate 70 kDa protein 2 [KO:K03283]
119316034  heat shock cognate 70 kDa protein-like [KO:K03283]
119316036  heat shock cognate 70 kDa protein-like [KO:K03283]
119279605  heat shock cognate 70 kDa protein-like [KO:K03283]
119298943  uncharacterized protein LOC119298943 isoform X1 [KO:K03283]
119266643  heat shock 70 kDa protein 6, chloroplastic-like [KO:K03283]
119282457  heat shock 70 kDa protein 4-like [KO:K03283]
119299807  heat shock cognate 70 kDa protein 2-like [KO:K03283]
119300668  stromal 70 kDa heat shock-related protein, chloroplastic-like [KO:K03283]
119318121  heat shock cognate 70 kDa protein 2-like [KO:K03283]
119285282  heat shock cognate 70 kDa protein 2-like [KO:K03283]
119285286  heat shock cognate 70 kDa protein-like [KO:K03283]
119285290  heat shock cognate 70 kDa protein-like [KO:K03283]
119321396  heat shock cognate 70 kDa protein-like [KO:K03283]
119358258  heat shock 70 kDa protein 18-like [KO:K03283]
119269536  heat shock cognate 70 kDa protein-like [KO:K03283]
119303817  heat shock cognate 70 kDa protein 2-like [KO:K03283]
119322808  heat shock cognate 70 kDa protein 2-like [KO:K03283]
119271727  heat shock cognate 70 kDa protein-like [KO:K03283]
119307735  heat shock cognate 70 kDa protein 2-like [KO:K03283]
119308063  stromal 70 kDa heat shock-related protein, chloroplastic-like [KO:K03283]
119290807  heat shock cognate 70 kDa protein-like [KO:K03283]
119290816  heat shock cognate 70 kDa protein-like [KO:K03283]
119290821  heat shock cognate 70 kDa protein 2-like [KO:K03283]
119311675  dnaJ protein homolog 2-like [KO:K09503]
119312116  dnaJ protein homolog [KO:K09503]
119317370  chaperone protein dnaJ A6-like [KO:K09503]
119303000  dnaJ protein homolog 2-like [KO:K09503]
119303461  dnaJ protein homolog [KO:K09503]
119323069  chaperone protein dnaJ A6-like [KO:K09503]
119275970  chaperone protein dnaJ 49-like [KO:K09518]
119276668  chaperone protein dnaJ 49-like [KO:K09518]
119268163  chaperone protein dnaJ 49-like [KO:K09518]
119340611  chaperone protein dnaJ 49-like [KO:K09518]
119310744  heat shock protein 81-3 [KO:K04079]
119329636  heat shock protein 81-1 [KO:K04079]
119352813  heat shock protein 90-1-like [KO:K04079]
119336656  heat shock protein 81-1-like [KO:K04079]
119301997  heat shock protein 81-3-like [KO:K04079]
119361852  heat shock protein 83 [KO:K04079]
119311092  hsp70 nucleotide exchange factor FES1-like [KO:K09562]
119312545  hsp70-binding protein 1-like [KO:K09562]
119299767  hsp70 nucleotide exchange factor FES1-like [KO:K09562]
119285259  hsp70 nucleotide exchange factor FES1-like [KO:K09562]
119303837  hsp70-binding protein 1-like [KO:K09562]
119290844  hsp70 nucleotide exchange factor FES1-like [KO:K09562]
119343321  16.9 kDa class I heat shock protein 1-like [KO:K13993]
119310650  small heat shock protein, chloroplastic-like [KO:K13993]
119327735  26.2 kDa heat shock protein, mitochondrial-like [KO:K13993]
119345550  16.9 kDa class I heat shock protein 1-like [KO:K13993]
119293404  21.9 kDa heat shock protein-like [KO:K13993]
119314898  18.9 kDa heat shock protein-like [KO:K13993]
119330694  26.2 kDa heat shock protein, mitochondrial-like [KO:K13993]
119330737  16.0 kDa heat shock protein, peroxisomal [KO:K13993]
119330851  26.2 kDa heat shock protein, mitochondrial-like [KO:K13993]
119331008  26.2 kDa heat shock protein, mitochondrial-like [KO:K13993]
119331028  17.4 kDa class I heat shock protein-like [KO:K13993]
119367874  23.2 kDa heat shock protein-like [KO:K13993]
119368543  26.2 kDa heat shock protein, mitochondrial-like [KO:K13993]
119280619  16.6 kDa heat shock protein-like [KO:K13993]
119331905  26.2 kDa heat shock protein, mitochondrial-like [KO:K13993]
119332033  26.2 kDa heat shock protein, mitochondrial-like [KO:K13993]
119332073  26.2 kDa heat shock protein, mitochondrial-like [KO:K13993]
119332149  26.2 kDa heat shock protein, mitochondrial-like [KO:K13993]
119280959  17.5 kDa class II heat shock protein-like [KO:K13993]
119280961  17.5 kDa class II heat shock protein-like [KO:K13993]
119317337  18.6 kDa class III heat shock protein-like [KO:K13993]
119333290  26.2 kDa heat shock protein, mitochondrial-like [KO:K13993]
119333294  26.2 kDa heat shock protein, mitochondrial-like [KO:K13993]
119333404  26.2 kDa heat shock protein, mitochondrial-like [KO:K13993]
119266736  16.9 kDa class I heat shock protein 1-like [KO:K13993]
119266738  16.9 kDa class I heat shock protein 1 [KO:K13993]
119266742  17.9 kDa heat shock protein 2-like [KO:K13993]
119266743  17.9 kDa heat shock protein 2-like [KO:K13993]
119267259  17.5 kDa class II heat shock protein [KO:K13993]
119267260  17.5 kDa class II heat shock protein-like [KO:K13993]
119267261  17.5 kDa class II heat shock protein-like [KO:K13993]
119317943  24.1 kDa heat shock protein, mitochondrial-like [KO:K13993]
119318162  18.6 kDa class III heat shock protein-like [KO:K13993]
119285111  small heat shock protein, chloroplastic-like [KO:K13993]
119319021  23.6 kDa heat shock protein, mitochondrial-like [KO:K13993]
119285223  17.4 kDa class I heat shock protein [KO:K13993]
119285225  17.9 kDa class I heat shock protein [KO:K13993]
119285229  17.9 kDa class I heat shock protein-like [KO:K13993]
119285230  17.9 kDa class I heat shock protein-like [KO:K13993]
119285231  17.9 kDa class I heat shock protein-like [KO:K13993]
119301978  small heat shock protein, chloroplastic-like [KO:K13993]
119286562  21.9 kDa heat shock protein-like isoform X1 [KO:K13993]
119322370  24.1 kDa heat shock protein, mitochondrial-like [KO:K13993]
119338110  17.5 kDa class II heat shock protein-like [KO:K13993]
119357807  18.8 kDa class V heat shock protein-like [KO:K13993]
119357890  26.2 kDa heat shock protein, mitochondrial-like [KO:K13993]
119322656  18.6 kDa class III heat shock protein-like [KO:K13993]
119338319  26.2 kDa heat shock protein, mitochondrial-like [KO:K13993]
119338408  26.2 kDa heat shock protein, mitochondrial-like [KO:K13993]
119338694  26.2 kDa heat shock protein, mitochondrial-like [KO:K13993]
119338696  26.2 kDa heat shock protein, mitochondrial-like [KO:K13993]
119338997  26.2 kDa heat shock protein, mitochondrial-like [KO:K13993]
119359545  23.2 kDa heat shock protein-like [KO:K13993]
119305694  16.9 kDa class I heat shock protein 1-like [KO:K13993]
119340098  17.4 kDa class I heat shock protein-like [KO:K13993]
119271805  16.9 kDa class I heat shock protein 1-like [KO:K13993]
119288709  small heat shock protein, chloroplastic-like [KO:K13993]
119288710  small heat shock protein, chloroplastic [KO:K13993]
119288736  17.9 kDa class I heat shock protein-like [KO:K13993]
119324152  18.9 kDa heat shock protein-like [KO:K13993]
119340355  16.9 kDa class I heat shock protein 2-like [KO:K13993]
119340792  26.2 kDa heat shock protein, mitochondrial-like [KO:K13993]
119340934  26.2 kDa heat shock protein, mitochondrial-like [KO:K13993]
119325213  23.6 kDa heat shock protein, mitochondrial-like [KO:K13993]
119325378  18.6 kDa class III heat shock protein-like [KO:K13993]
119341357  16.0 kDa heat shock protein, peroxisomal-like [KO:K13993]
119341853  26.2 kDa heat shock protein, mitochondrial-like [KO:K13993]
119363473  18.8 kDa class V heat shock protein-like isoform X1 [KO:K13993]
119274533  17.9 kDa heat shock protein 2-like [KO:K13993]
119274534  17.9 kDa heat shock protein 2-like [KO:K13993]
119274538  16.9 kDa class I heat shock protein 1-like [KO:K13993]
119274539  16.9 kDa class I heat shock protein 1-like [KO:K13993]
119275112  17.5 kDa class II heat shock protein-like [KO:K13993]
119275113  17.5 kDa class II heat shock protein-like [KO:K13993]
119275114  17.5 kDa class II heat shock protein-like [KO:K13993]
119275116  17.5 kDa class II heat shock protein-like [KO:K13993]
119275117  17.5 kDa class II heat shock protein-like [KO:K13993]
119275118  17.5 kDa class II heat shock protein-like [KO:K13993]
119290871  17.9 kDa class I heat shock protein-like [KO:K13993]
119290873  17.4 kDa class I heat shock protein-like [KO:K13993]
119290878  17.9 kDa class I heat shock protein-like [KO:K13993]
119290879  17.4 kDa class I heat shock protein-like [KO:K13993]
119291006  small heat shock protein, chloroplastic-like [KO:K13993]
119315422  OVARIAN TUMOR DOMAIN-containing deubiquitinating enzyme 2-like [KO:K13719] [EC:3.1.2.-]
119324595  OVARIAN TUMOR DOMAIN-containing deubiquitinating enzyme 2-like [KO:K13719] [EC:3.1.2.-]
119363858  phospholipase A-2-activating protein-like [KO:K14018]
119354763  phospholipase A-2-activating protein-like [KO:K14018]
119301361  uncharacterized protein LOC119301361 [KO:K14018]
119309356  probable ubiquitin receptor RAD23 isoform X1 [KO:K10839]
119343461  ubiquitin receptor RAD23b-like [KO:K10839]
119328289  ubiquitin receptor RAD23d-like [KO:K10839]
119316278  ubiquitin receptor RAD23b-like [KO:K10839]
119301510  probable ubiquitin receptor RAD23 isoform X1 [KO:K10839]
119335779  ubiquitin receptor RAD23d-like [KO:K10839]
119322451  ubiquitin receptor RAD23b-like isoform X1 [KO:K10839]
119291875  ubiquitin domain-containing protein DSK2a-like isoform X1 [KO:K04523]
119303984  ubiquitin domain-containing protein DSK2a-like isoform X1 [KO:K04523]
119338235  ubiquitin domain-containing protein DSK2b-like [KO:K04523]
119274388  ubiquitin domain-containing protein DSK2a-like [KO:K04523]
119363582  peptide-N(4)-(N-acetyl-beta- glucosaminyl)asparagine amidase-like isoform X1 [KO:K01456] [EC:3.5.1.52]
119354351  peptide-N(4)-(N-acetyl-beta- glucosaminyl)asparagine amidase-like [KO:K01456] [EC:3.5.1.52]
119346669  putative ataxin-3 homolog [KO:K11863] [EC:3.4.22.-]
119277618  putative ataxin-3 homolog [KO:K11863] [EC:3.4.22.-]
119281677  ataxin-3 homolog [KO:K11863] [EC:3.4.22.-]
119269603  putative ataxin-3 homolog [KO:K11863] [EC:3.4.22.-]
119329869  probable ubiquitin conjugation factor E4 [KO:K10597] [EC:2.3.2.27]
119337590  probable ubiquitin conjugation factor E4 [KO:K10597] [EC:2.3.2.27]
119296396  eukaryotic translation initiation factor 2 subunit alpha homolog [KO:K03237]
119353149  eukaryotic translation initiation factor 2 subunit alpha homolog [KO:K03237]
119285426  eukaryotic translation initiation factor 2 subunit alpha homolog [KO:K03237]
119362246  eukaryotic translation initiation factor 2 subunit alpha homolog [KO:K03237]
119328603  subtilisin-like protease SBT6.1 [KO:K08653] [EC:3.4.21.112]
119341286  subtilisin-like protease SBT6.1 [KO:K08653] [EC:3.4.21.112]
119318425  serine/threonine-protein kinase/endoribonuclease IRE1-like isoform X1 [KO:K08852] [EC:2.7.11.1 3.1.26.-]
119324001  serine/threonine-protein kinase/endoribonuclease IRE1-like [KO:K08852] [EC:2.7.11.1 3.1.26.-]
119328850  probable E3 ubiquitin ligase SUD1 isoform X1 [KO:K10661] [EC:2.3.2.27]
119330009  probable E3 ubiquitin ligase SUD1 [KO:K10661] [EC:2.3.2.27]
119349063  probable E3 ubiquitin ligase SUD1 [KO:K10661] [EC:2.3.2.27]
119349071  probable E3 ubiquitin ligase SUD1 [KO:K10661] [EC:2.3.2.27]
119349790  probable E3 ubiquitin ligase SUD1 [KO:K10661] [EC:2.3.2.27]
119349795  probable E3 ubiquitin ligase SUD1 [KO:K10661] [EC:2.3.2.27]
119350991  probable E3 ubiquitin ligase SUD1 [KO:K10661] [EC:2.3.2.27]
119300120  probable E3 ubiquitin ligase SUD1 [KO:K10661] [EC:2.3.2.27]
119336784  probable E3 ubiquitin ligase SUD1 isoform X1 [KO:K10661] [EC:2.3.2.27]
119356802  probable E3 ubiquitin ligase SUD1 [KO:K10661] [EC:2.3.2.27]
119356857  probable E3 ubiquitin ligase SUD1 [KO:K10661] [EC:2.3.2.27]
119338058  probable E3 ubiquitin ligase SUD1 isoform X1 [KO:K10661] [EC:2.3.2.27]
119285508  ubiquitin-conjugating enzyme E2 32-like [KO:K10578] [EC:2.3.2.23]
119296295  ubiquitin-conjugating enzyme E2 32-like [KO:K10578] [EC:2.3.2.23]
119328559  ubiquitin-conjugating enzyme E2 34-like [KO:K04554] [EC:2.3.2.23]
119335651  ubiquitin-conjugating enzyme E2 34-like [KO:K04554] [EC:2.3.2.23]
119347455  ubiquitin-conjugating enzyme E2 7-like [KO:K10575] [EC:2.3.2.23]
119277544  ubiquitin-conjugating enzyme E2 7 [KO:K10575] [EC:2.3.2.23]
119282468  ubiquitin-conjugating enzyme E2 7-like [KO:K10575] [EC:2.3.2.23]
119269529  ubiquitin-conjugating enzyme E2 7 [KO:K10575] [EC:2.3.2.23]
119328600  ERAD-associated E3 ubiquitin-protein ligase HRD1-like [KO:K10601] [EC:2.3.2.27]
119334741  ERAD-associated E3 ubiquitin-protein ligase HRD1-like [KO:K10601] [EC:2.3.2.27]
119335740  ERAD-associated E3 ubiquitin-protein ligase HRD1-like [KO:K10601] [EC:2.3.2.27]
119283519  uncharacterized protein LOC119283519 [KO:K10666] [EC:2.3.2.27]
119269466  uncharacterized protein LOC119269466 [KO:K10666] [EC:2.3.2.27]
119348582  uncharacterized protein LOC119348582 [KO:K10666] [EC:2.3.2.27]
119294628  E3 ubiquitin-protein ligase RNF185-like [KO:K10666] [EC:2.3.2.27]
119364914  E3 ubiquitin-protein ligase RMA1H1-like [KO:K10666] [EC:2.3.2.27]
119355775  E3 ubiquitin-protein ligase RMA1H1-like [KO:K10666] [EC:2.3.2.27]
119277467  uncharacterized protein LOC119277467 [KO:K10666] [EC:2.3.2.27]
119281550  E3 ubiquitin-protein ligase RNF185-like [KO:K10666] [EC:2.3.2.27]
119298773  E3 ubiquitin-protein ligase RNF5-like [KO:K10666] [EC:2.3.2.27]
119307022  E3 ubiquitin-protein ligase RNF5-like [KO:K10666] [EC:2.3.2.27]
119287086  E3 ubiquitin-protein ligase RNF5-like [KO:K10666] [EC:2.3.2.27]
119285168  ERAD-associated E3 ubiquitin-protein ligase component HRD3 [KO:K14026]
119322701  ERAD-associated E3 ubiquitin-protein ligase component HRD3-like [KO:K14026]
119290939  ERAD-associated E3 ubiquitin-protein ligase component HRD3-like isoform X1 [KO:K14026]
119363609  E3 ubiquitin protein ligase RIN2-like [KO:K10636] [EC:2.3.2.36]
119354388  E3 ubiquitin protein ligase RIN2-like [KO:K10636] [EC:2.3.2.36]
119315700  E3 ubiquitin-protein ligase CHIP-like [KO:K09561] [EC:2.3.2.27]
119331036  E3 ubiquitin-protein ligase CHIP-like [KO:K09561] [EC:2.3.2.27]
119358152  E3 ubiquitin-protein ligase CHIP-like [KO:K09561] [EC:2.3.2.27]
119340656  E3 ubiquitin-protein ligase CHIP-like [KO:K09561] [EC:2.3.2.27]
119276439  ubiquitin-conjugating enzyme E2 5A [KO:K06689] [EC:2.3.2.23]
119348697  ubiquitin-conjugating enzyme E2-17 kDa-like [KO:K06689] [EC:2.3.2.23]
119277402  ubiquitin-conjugating enzyme E2-17 kDa-like isoform X1 [KO:K06689] [EC:2.3.2.23]
119366206  ubiquitin-conjugating enzyme E2 28-like [KO:K06689] [EC:2.3.2.23]
119366245  ubiquitin-conjugating enzyme E2 28-like [KO:K06689] [EC:2.3.2.23]
119314552  ubiquitin-conjugating enzyme E2 28-like [KO:K06689] [EC:2.3.2.23]
119330976  ubiquitin-conjugating enzyme E2 28 [KO:K06689] [EC:2.3.2.23]
119283646  ubiquitin-conjugating enzyme E2 28-like [KO:K06689] [EC:2.3.2.23]
119283649  ubiquitin-conjugating enzyme E2 28-like [KO:K06689] [EC:2.3.2.23]
119283951  ubiquitin-conjugating enzyme E2-17 kDa-like [KO:K06689] [EC:2.3.2.23]
119301227  ubiquitin-conjugating enzyme E2 28-like [KO:K06689] [EC:2.3.2.23]
119268542  ubiquitin-conjugating enzyme E2 5A [KO:K06689] [EC:2.3.2.23]
119356985  ubiquitin-conjugating enzyme E2 28-like [KO:K06689] [EC:2.3.2.23]
119269405  ubiquitin-conjugating enzyme E2-17 kDa-like isoform X1 [KO:K06689] [EC:2.3.2.23]
119337941  ubiquitin-conjugating enzyme E2 28 [KO:K06689] [EC:2.3.2.23]
119273092  uncharacterized protein LOC119273092 [KO:K06689] [EC:2.3.2.23]
119325717  ubiquitin-conjugating enzyme E2 28-like [KO:K06689] [EC:2.3.2.23]
119308764  ubiquitin-conjugating enzyme E2 28-like [KO:K06689] [EC:2.3.2.23]
119317601  E3 ubiquitin-protein ligase RBX1-like [KO:K03868] [EC:2.3.2.32]
119266566  RING-box protein 1 [KO:K03868] [EC:2.3.2.32]
119323775  E3 ubiquitin-protein ligase RBX1-like [KO:K03868] [EC:2.3.2.32]
119274241  RING-box protein 1-like [KO:K03868] [EC:2.3.2.32]
119325922  cullin-1-like [KO:K03347]
119325931  cullin-1 isoform X1 [KO:K03347]
119364875  cullin-1-like [KO:K03347]
119364884  cullin-1-like isoform X1 [KO:K03347]
119280599  cullin-1-like [KO:K03347]
119326527  SKP1-like protein 1 [KO:K03094]
119326586  SKP1-like protein 1 [KO:K03094]
119343323  SKP1-like protein 1 [KO:K03094]
119343824  SKP1-like protein 1 [KO:K03094]
119344731  SKP1-like protein 1 [KO:K03094]
119327523  SKP1-like protein 1 [KO:K03094]
119345842  SKP1-like protein 1 [KO:K03094]
119311362  SKP1-like protein 1 [KO:K03094]
119329140  SKP1-like protein 1 [KO:K03094]
119294136  SKP1-like protein 1 [KO:K03094]
119314486  SKP1-like protein 1 [KO:K03094]
119330811  SKP1-like protein 1 [KO:K03094]
119331018  SKP1-like protein 1 [KO:K03094]
119352235  SKP1-like protein 1 [KO:K03094]
119352492  SKP1-like protein 4 [KO:K03094]
119368195  SKP1-like protein 1 [KO:K03094]
119368651  SKP1-like protein 1 [KO:K03094]
119280830  SKP1-like protein 4 [KO:K03094]
119297104  SKP1-like protein 1 [KO:K03094]
119297257  SKP1-like protein 11 [KO:K03094]
119297584  SKP1-like protein 1 [KO:K03094]
119298403  SKP1-like protein 4 isoform X1 [KO:K03094]
119331798  SKP1-like protein 11 [KO:K03094]
119281772  SKP1-like protein 1 [KO:K03094]
119333929  SKP1-like protein 1A [KO:K03094]
119284037  SKP1-like protein 1 [KO:K03094]
119300041  SKP1-like protein 1A [KO:K03094]
119319133  SKP1-like protein 1 [KO:K03094]
119319174  SKP1-like protein 1 [KO:K03094]
119302685  SKP1-like protein 1 [KO:K03094]
119322681  SKP1-like protein 1 [KO:K03094]
119305299  SKP1-like protein 1 [KO:K03094]
119305466  SKP1-like protein 1 isoform X1 [KO:K03094]
119340093  SKP1-like protein 1 [KO:K03094]
119272353  SKP1-like protein 1 [KO:K03094]
119288277  SKP1-like protein 1 [KO:K03094]
119306003  SKP1-like protein 1 [KO:K03094]
119306173  SKP1-like protein 4 [KO:K03094]
119341103  SKP1-like protein 1 [KO:K03094]
119273360  SKP1-like protein 11 [KO:K03094]
119273567  SKP1-like protein 1 [KO:K03094]
119274168  SKP1-like protein 1 [KO:K03094]
119289511  SKP1-like protein 1 [KO:K03094]
119289662  SKP1-like protein 1 [KO:K03094]
119289663  SKP1-like protein 1 [KO:K03094]
Compound
C00076  Calcium cation
G00009   
G00010   
G00011   
G00012   
G10694   
Reference
PMID:19491040
  Authors
Naidoo N
  Title
ER and aging-Protein folding and the ER stress response.
  Journal
Ageing Res Rev 8:150-9 (2009)
DOI:10.1016/j.arr.2009.03.001
Reference
PMID:18023214
  Authors
Malhotra JD, Kaufman RJ
  Title
The endoplasmic reticulum and the unfolded protein response.
  Journal
Semin Cell Dev Biol 18:716-31 (2007)
DOI:10.1016/j.semcdb.2007.09.003
Reference
PMID:20347046
  Authors
Maattanen P, Gehring K, Bergeron JJ, Thomas DY
  Title
Protein quality control in the ER: the recognition of misfolded proteins.
  Journal
Semin Cell Dev Biol 21:500-11 (2010)
DOI:10.1016/j.semcdb.2010.03.006
Reference
PMID:20219571
  Authors
Stolz A, Wolf DH
  Title
Endoplasmic reticulum associated protein degradation: a chaperone assisted journey to hell.
  Journal
Biochim Biophys Acta 1803:694-705 (2010)
DOI:10.1016/j.bbamcr.2010.02.005
Reference
PMID:20112977
  Authors
Dejgaard K, Theberge JF, Heath-Engel H, Chevet E, Tremblay ML, Thomas DY
  Title
Organization of the Sec61 translocon, studied by high resolution native electrophoresis.
  Journal
J Proteome Res 9:1763-71 (2010)
DOI:10.1021/pr900900x
Related
pathway
tdc00510  N-Glycan biosynthesis
tdc03050  Proteasome
tdc03060  Protein export
KO pathway
ko04141   
LinkDB

DBGET integrated database retrieval system