KEGG   PATHWAY: padl05132
Entry
padl05132                   Pathway                                
Name
Salmonella infection - Pygoscelis adeliae (Adelie penguin)
Description
Salmonella infection usually presents as a self-limiting gastroenteritis or the more severe typhoid fever and bacteremia. The common disease-causing Salmonella species in human is a single species, Salmonella enterica, which has numerous serovars.
Following intestinal colonization Salmonella inject effector proteins into the host cells using a type III secretion system (T3SS), T3SS1. Then a small group of effector proteins induce rearrangement of the actin cytoskeleton resulting in membrane ruffles and rapid internalization of the bacteria.The T3SS2 is responsible for translocating effector proteins that direct Salmonella-containing vacuole (SCV) maturation. The majority of the bacteria are known to survive and replicate in SCV.
Class
Human Diseases; Infectious disease: bacterial
Pathway map
padl05132  Salmonella infection
padl05132

Organism
Pygoscelis adeliae (Adelie penguin) [GN:padl]
Gene
103920834  PODXL; podocalyxin isoform X1 [KO:K06817]
103918772  PTPRC; receptor-type tyrosine-protein phosphatase C [KO:K06478] [EC:3.1.3.48]
103921524  RAB5A; ras-related protein Rab-5A [KO:K07887]
103919498  RAB5C; ras-related protein Rab-5C [KO:K07889]
103923250  PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
103914394  RAB7A; ras-related protein Rab-7a [KO:K07897]
103919790  RAB7B; ras-related protein Rab-7b [KO:K07898]
103926095  PLEKHM1; pleckstrin homology domain-containing family M member 1 [KO:K23282]
103916411  VPS11; vacuolar protein sorting-associated protein 11 homolog [KO:K20179]
103912861  VPS18; vacuolar protein sorting-associated protein 18 homolog [KO:K20181]
103914570  VPS33A; vacuolar protein sorting-associated protein 33A [KO:K20182]
103912843  VPS39; vam6/Vps39-like protein [KO:K20183]
103914738  VPS41; vacuolar protein sorting-associated protein 41 homolog [KO:K20184]
103920682  DYNC1H1; LOW QUALITY PROTEIN: cytoplasmic dynein 1 heavy chain 1 [KO:K10413]
103915449  DYNC2H1; LOW QUALITY PROTEIN: cytoplasmic dynein 2 heavy chain 1 [KO:K10414]
103922371  DYNC1I1; cytoplasmic dynein 1 intermediate chain 1 isoform X1 [KO:K10415]
103918176  DYNC1I2; cytoplasmic dynein 1 intermediate chain 2 [KO:K10415]
103913763  DYNC1LI2; cytoplasmic dynein 1 light intermediate chain 2 [KO:K10416]
103917101  DYNC1LI1; cytoplasmic dynein 1 light intermediate chain 1 [KO:K10416]
103918085  DYNC2LI1; LOW QUALITY PROTEIN: cytoplasmic dynein 2 light intermediate chain 1 [KO:K10417]
103921178  DYNLL2; dynein light chain 2, cytoplasmic [KO:K10418]
103922633  dynein light chain 1, cytoplasmic [KO:K10418]
103922634  dynein light chain 1, cytoplasmic-like [KO:K10418]
103912418  DYNLRB1; dynein light chain roadblock-type 1 [KO:K10419]
103923888  DYNLRB2; dynein light chain roadblock-type 2 [KO:K10419]
103912618  DYNLT3; dynein light chain Tctex-type 3 [KO:K10420]
103912765  DYNLT1; dynein light chain Tctex-type 1 [KO:K10420]
103923706  DCTN1; dynactin subunit 1 [KO:K04648]
103925918  DCTN3; dynactin subunit 3 [KO:K10425]
103915739  DCTN4; LOW QUALITY PROTEIN: dynactin subunit 4 [KO:K10426]
103913913  DCTN5; dynactin subunit 5 [KO:K10427]
103913387  DCTN6; dynactin subunit 6 [KO:K10428]
103916306  ACTR1A; alpha-centractin [KO:K16575]
103923081  ACTR10; actin-related protein 10 [KO:K16576]
103913812  tubulin alpha-8 chain [KO:K07374]
103920502  TUBA4A; tubulin alpha-4A chain [KO:K07374]
103917691  tubulin alpha chain [KO:K07374]
103925283  tubulin alpha-3 chain [KO:K07374]
103924356  TUBA8; tubulin alpha-8 chain [KO:K07374]
103924357  tubulin alpha-4 chain-like [KO:K07374]
103920837  tubulin alpha-3 chain [KO:K07374]
103922812  TUBAL3; tubulin alpha chain-like 3 isoform X1 [KO:K07374]
103912279  TUBB6; tubulin beta-6 chain [KO:K07375]
103918933  tubulin beta chain [KO:K07375]
103919015  tubulin beta-2 chain [KO:K07375]
103919295  TUBB1; tubulin beta-1 chain [KO:K07375]
103922995  FYCO1; FYVE and coiled-coil domain-containing protein 1 [KO:K21954]
103913816  ARL8A; ADP-ribosylation factor-like protein 8A [KO:K07955]
103923852  ADP-ribosylation factor-like protein 8B [KO:K07955]
103922479  ARL8B; ADP-ribosylation factor-like protein 8B [KO:K07955]
103922242  PLEKHM2; pleckstrin homology domain-containing family M member 2 [KO:K15348]
103912665  KIF5C; kinesin heavy chain isoform 5C [KO:K10396]
103918263  KIF5B; kinesin-1 heavy chain [KO:K10396]
103913697  KLC4; kinesin light chain 4 isoform X1 [KO:K10407]
103920103  KLC1; kinesin light chain 1 isoform X1 [KO:K10407]
103925048  ACBD3; Golgi resident protein GCP60 [KO:K23935]
103925495  RHOA; transforming protein RhoA [KO:K04513]
103922185  M6PR; cation-dependent mannose-6-phosphate receptor [KO:K10089]
103924810  RAB9A; ras-related protein Rab-9A [KO:K07899]
103923325  RAB9B; ras-related protein Rab-9B [KO:K07900]
103918879  GCC2; GRIP and coiled-coil domain-containing protein 2 [KO:K20282]
103913191  PFN4; profilin-4 [KO:K05759]
103925063  PFN3; LOW QUALITY PROTEIN: profilin-3 [KO:K05759]
103925311  PFN2; profilin-2 [KO:K05759]
103917482  EXOC7; exocyst complex component 7 [KO:K07195]
103923086  EXOC5; exocyst complex component 5 [KO:K19984]
103920845  EXOC4; exocyst complex component 4 [KO:K06111]
103919009  EXOC2; exocyst complex component 2 [KO:K17637]
103914767  RALA; ras-related protein Ral-A [KO:K07834]
103913542  ACTB; actin, cytoplasmic 1 [KO:K05692]
103921982  ANXA2; annexin A2 [KO:K17092]
103922229  LOW QUALITY PROTEIN: neuroblast differentiation-associated protein AHNAK-like [KO:K23934]
103920526  AHNAK2; protein AHNAK2 [KO:K23934]
103924239  RHOJ; rho-related GTP-binding protein RhoJ [KO:K07864]
103925306  ARHGEF26; rho guanine nucleotide exchange factor 26 [KO:K13744]
103912140  rho-related GTP-binding protein RhoG [KO:K07863]
103923340  rho-related GTP-binding protein RhoG-like [KO:K07863]
103923971  engulfment and cell motility protein 1-like [KO:K12366]
103923990  engulfment and cell motility protein 1 [KO:K12366]
103921868  ELMO2; engulfment and cell motility protein 2 isoform X1 [KO:K18985]
103924034  ROCK2; LOW QUALITY PROTEIN: rho-associated protein kinase 2 [KO:K17388] [EC:2.7.11.39]
103914543  MYL2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform isoform X1 [KO:K10351]
103921386  MYL9; myosin regulatory light polypeptide 9 [KO:K12755]
103912916  MYL10; myosin regulatory light chain 10 [KO:K12756]
103917825  myosin regulatory light chain 2, smooth muscle minor isoform-like [KO:K12757]
103917836  myosin regulatory light chain 2, smooth muscle minor isoform [KO:K12757]
103922268  FHOD1; FH1/FH2 domain-containing protein 1 [KO:K23938]
103925407  CDC42; cell division control protein 42 homolog isoform X1 [KO:K04393]
103913498  RAC1; ras-related C3 botulinum toxin substrate 1 [KO:K04392]
103921671  NCKAP1; nck-associated protein 1 [KO:K05750]
103924911  CYFIP2; cytoplasmic FMR1-interacting protein 2 isoform X1 [KO:K05749]
103923041  CYFIP1; cytoplasmic FMR1-interacting protein 1 [KO:K05749]
103921207  ABI1; abl interactor 1 [KO:K23649]
103920100  WASF3; wiskott-Aldrich syndrome protein family member 3 [KO:K06083]
103916354  wiskott-Aldrich syndrome protein family member 3-like [KO:K06083]
103917830  ACTR2; actin-related protein 2 [KO:K17260]
103915636  ACTR3B; actin-related protein 3B [KO:K18584]
103918500  actin-related protein 3 [KO:K18584]
103914104  ARPC1A; actin-related protein 2/3 complex subunit 1A [KO:K05757]
103918799  ARPC1B; actin-related protein 2/3 complex subunit 1B [KO:K05757]
103914267  ARPC2; actin-related protein 2/3 complex subunit 2 [KO:K05758]
103914553  ARPC3; actin-related protein 2/3 complex subunit 3 [KO:K05756]
103917495  ARPC5; actin-related protein 2/3 complex subunit 5 [KO:K05754]
103915162  PAK1; serine/threonine-protein kinase PAK 1 [KO:K04409] [EC:2.7.11.1]
103920160  PAK3; serine/threonine-protein kinase PAK 3 [KO:K05733] [EC:2.7.11.1]
103924668  MYO6; LOW QUALITY PROTEIN: unconventional myosin-VI [KO:K10358]
103914966  PIK3CA; LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
103917840  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
103917969  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
103920571  PIK3CG; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform [KO:K21289] [EC:2.7.1.153]
103924344  PIK3C2G; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma [KO:K00923] [EC:2.7.1.154]
103920719  PIK3C2A; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha [KO:K00923] [EC:2.7.1.154]
103919855  PIK3C2B; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta [KO:K00923] [EC:2.7.1.154]
103913549  CYTH3; cytohesin-3 [KO:K18441]
103924149  CYTH4; cytohesin-4 [KO:K18441]
103917409  CYTH1; cytohesin-1 [KO:K18441]
103913236  ADP-ribosylation factor 6-like [KO:K07941]
103914904  ARF6; ADP-ribosylation factor 6 [KO:K07941]
103924708  ARF1; ADP-ribosylation factor 1 [KO:K07937]
103912728  SNX9; sorting nexin-9 isoform X1 [KO:K17923]
103922045  SNX33; sorting nexin-33 [KO:K17923]
103919447  SNX18; sorting nexin-18 [KO:K17923]
103923835  WASL; neural Wiskott-Aldrich syndrome protein [KO:K23612]
103914840  DNM2; dynamin-2 [KO:K23484] [EC:3.6.5.5]
103914703  toll-like receptor 6 [KO:K10169]
103921773  toll-like receptor 2 type-1 [KO:K10159]
103921774  toll-like receptor 2 type-2 [KO:K10159]
103916420  TIRAP; toll/interleukin-1 receptor domain-containing adapter protein [KO:K05403]
103924746  MYD88; myeloid differentiation primary response protein MyD88 [KO:K04729]
103921595  CD14; monocyte differentiation antigen CD14 [KO:K04391]
103912903  TLR4; LOW QUALITY PROTEIN: toll-like receptor 4 [KO:K10160]
103926189  LY96; lymphocyte antigen 96 [KO:K05400]
103925024  TLR5; toll-like receptor 5 [KO:K10168]
103919991  IRAK4; interleukin-1 receptor-associated kinase 4 [KO:K04733] [EC:2.7.11.1]
103921676  TRAF6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
103913621  MAP3K7; mitogen-activated protein kinase kinase kinase 7 isoform X1 [KO:K04427] [EC:2.7.11.25]
103915676  TAB1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 [KO:K04403]
103917026  TAB2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1 [KO:K04404]
103925971  TAB3; TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X1 [KO:K12793]
103924297  CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [KO:K04467] [EC:2.7.11.10]
103920554  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [KO:K07209] [EC:2.7.11.10]
103912947  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
103919520  NFKB1; nuclear factor NF-kappa-B p105 subunit [KO:K02580]
103917059  NOD1; nucleotide-binding oligomerization domain-containing protein 1 [KO:K08727]
103920298  HSP90AA1; heat shock protein HSP 90-alpha [KO:K04079]
103922900  HSP90AB1; heat shock protein HSP 90-beta [KO:K04079]
103924528  HSP90B1; endoplasmin [KO:K09487]
103914195  receptor-interacting serine/threonine-protein kinase 2-like isoform X1 [KO:K08846] [EC:2.7.11.1]
103917314  RIPK2; receptor-interacting serine/threonine-protein kinase 2 [KO:K08846] [EC:2.7.11.1]
103919261  CSE1L; exportin-2 [KO:K18423]
103921143  KPNA1; importin subunit alpha-5 [KO:K23940]
103913485  KPNA3; importin subunit alpha-4 [KO:K23583]
103925239  KPNA4; importin subunit alpha-3 [KO:K23583]
103915188  RPS3; 40S ribosomal protein S3 [KO:K02985]
103916453  HRAS; GTPase HRas [KO:K02833]
103915210  RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
103914812  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
103916484  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
103922585  MAPK1; LOW QUALITY PROTEIN: mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
103918788  MAP2K3; dual specificity mitogen-activated protein kinase kinase 3 [KO:K04432] [EC:2.7.12.2]
103916640  MAP2K6; LOW QUALITY PROTEIN: dual specificity mitogen-activated protein kinase kinase 6 [KO:K04433] [EC:2.7.12.2]
103925940  MAPK13; mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
103925963  MAPK14; mitogen-activated protein kinase 14 [KO:K04441] [EC:2.7.11.24]
103923636  MAPK12; mitogen-activated protein kinase 12 [KO:K04441] [EC:2.7.11.24]
103923637  MAPK11; mitogen-activated protein kinase 11 [KO:K04441] [EC:2.7.11.24]
103925347  MAP2K4; dual specificity mitogen-activated protein kinase kinase 4 [KO:K04430] [EC:2.7.12.2]
103915758  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
103913739  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
103918603  MAPK10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
103913320  JUN; transcription factor AP-1 [KO:K04448]
103912923  interleukin-1 beta-like [KO:K04519]
103918452  IL6; interleukin-6 [KO:K05405]
103917696  interleukin-8-like [KO:K10030]
103917698  interleukin-8 [KO:K10030]
103917699  C-X-C motif chemokine 5-like [KO:K10030]
103917711  LOW QUALITY PROTEIN: interleukin-8-like [KO:K10030]
103914490  CTNNB1; catenin beta-1 [KO:K02105]
103915850  TCF7; transcription factor 7 [KO:K02620]
103918670  TCF7L2; transcription factor 7-like 2 [KO:K04491]
103919538  LEF1; LOW QUALITY PROTEIN: lymphoid enhancer-binding factor 1 [KO:K04492]
103922038  FBXO22; F-box only protein 22 [KO:K10302]
103915789  SKP1; S-phase kinase-associated protein 1 [KO:K03094]
103922177  tumor necrosis factor receptor superfamily member 1A-like [KO:K03158]
103921138  TRAF2; TNF receptor-associated factor 2 [KO:K03173] [EC:2.3.2.27]
103914203  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein [KO:K03171]
103918923  BIRC2; baculoviral IAP repeat-containing protein 2 [KO:K16060]
103919013  RIPK1; receptor-interacting serine/threonine-protein kinase 1 isoform X1 [KO:K02861] [EC:2.7.11.1]
103921100  GAPDH; glyceraldehyde-3-phosphate dehydrogenase [KO:K00134] [EC:1.2.1.12]
103924981  TNFSF10; tumor necrosis factor ligand superfamily member 10 [KO:K04721]
103925771  FADD; FAS-associated death domain protein [KO:K02373]
103924262  CASP8; caspase-8 [KO:K04398] [EC:3.4.22.61]
103923440  caspase-8-like [KO:K04398] [EC:3.4.22.61]
103919822  BAK1; bcl-2 homologous antagonist/killer [KO:K14021]
103918416  cytochrome c [KO:K08738]
103923966  LOW QUALITY PROTEIN: cytochrome c, somatic-like [KO:K08738]
103919231  BCL2; apoptosis regulator Bcl-2 [KO:K02161]
103922530  CASP3; caspase-3 [KO:K02187] [EC:3.4.22.56]
103918570  CASP7; caspase-7 [KO:K04397] [EC:3.4.22.60]
103926227  caspase-3-like [KO:K04397] [EC:3.4.22.60]
103922167  rho-related GTP-binding protein RhoB [KO:K07856]
103924005  RHOH; rho-related GTP-binding protein RhoH [KO:K07873]
103914586  AKT3; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
103919989  AKT1; RAC-alpha serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
103916212  LOW QUALITY PROTEIN: RAC-beta serine/threonine-protein kinase-like [KO:K04456] [EC:2.7.11.1]
103918117  MLKL; mixed lineage kinase domain-like protein [KO:K08849] [EC:2.7.11.1]
103921088  TXN; thioredoxin [KO:K03671]
103925463  NLRP6; LOW QUALITY PROTEIN: NACHT, LRR and PYD domains-containing protein 6 [KO:K12800]
103921065  NAIP; LOW QUALITY PROTEIN: baculoviral IAP repeat-containing protein 1 [KO:K12807]
103922882  NLRC4; LOW QUALITY PROTEIN: NLR family CARD domain-containing protein 4 [KO:K12805]
103916608  caspase-1-like [KO:K01370] [EC:3.4.22.36]
103921543  IL18; interleukin-18 [KO:K05482]
Compound
C00338  Lipopolysaccharide
C01194  1-Phosphatidyl-D-myo-inositol
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
Reference
PMID:28875943
  Authors
Bernal-Bayard J, Ramos-Morales F
  Title
Molecular Mechanisms Used by Salmonella to Evade the Immune System.
  Journal
Curr Issues Mol Biol 25:133-168 (2018)
DOI:10.21775/cimb.025.133
Reference
PMID:28848711
  Authors
Hume PJ, Singh V, Davidson AC, Koronakis V
  Title
Swiss Army Pathogen: The Salmonella Entry Toolkit.
  Journal
Front Cell Infect Microbiol 7:348 (2017)
DOI:10.3389/fcimb.2017.00348
Reference
PMID:31402916
  Authors
Wemyss MA, Pearson JS
  Title
Host Cell Death Responses to Non-typhoidal Salmonella Infection.
  Journal
Front Immunol 10:1758 (2019)
DOI:10.3389/fimmu.2019.01758
Reference
PMID:27974148
  Authors
Bierschenk D, Boucher D, Schroder K
  Title
Salmonella-induced inflammasome activation in humans.
  Journal
Mol Immunol 86:38-43 (2017)
DOI:10.1016/j.molimm.2016.11.009
Reference
PMID:29477730
  Authors
Pinaud L, Sansonetti PJ, Phalipon A
  Title
Host Cell Targeting by Enteropathogenic Bacteria T3SS Effectors.
  Journal
Trends Microbiol 26:266-283 (2018)
DOI:10.1016/j.tim.2018.01.010
Reference
PMID:25749450
  Authors
LaRock DL, Chaudhary A, Miller SI
  Title
Salmonellae interactions with host processes.
  Journal
Nat Rev Microbiol 13:191-205 (2015)
DOI:10.1038/nrmicro3420
Reference
PMID:17983751
  Authors
Ramsden AE, Holden DW, Mota LJ
  Title
Membrane dynamics and spatial distribution of Salmonella-containing vacuoles.
  Journal
Trends Microbiol 15:516-24 (2007)
DOI:10.1016/j.tim.2007.10.002
Reference
PMID:22702524
  Authors
van der Heijden J, Finlay BB
  Title
Type III effector-mediated processes in Salmonella infection.
  Journal
Future Microbiol 7:685-703 (2012)
DOI:10.2217/fmb.12.49
Reference
PMID:27222578
  Authors
Galan JE
  Title
Typhoid toxin provides a window into typhoid fever and the biology of Salmonella Typhi.
  Journal
Proc Natl Acad Sci U S A 113:6338-44 (2016)
DOI:10.1073/pnas.1606335113
Reference
PMID:19157959
  Authors
McGhie EJ, Brawn LC, Hume PJ, Humphreys D, Koronakis V
  Title
Salmonella takes control: effector-driven manipulation of the host.
  Journal
Curr Opin Microbiol 12:117-24 (2009)
DOI:10.1016/j.mib.2008.12.001
Reference
PMID:12675800
  Authors
Miao EA, Brittnacher M, Haraga A, Jeng RL, Welch MD, Miller SI
  Title
Salmonella effectors translocated across the vacuolar membrane interact with the actin cytoskeleton.
  Journal
Mol Microbiol 48:401-15 (2003)
DOI:10.1046/j.1365-2958.2003.t01-1-03456.x
Reference
PMID:17074883
  Authors
Patel JC, Galan JE
  Title
Differential activation and function of Rho GTPases during Salmonella-host cell interactions.
  Journal
J Cell Biol 175:453-63 (2006)
DOI:10.1083/jcb.200605144
Reference
PMID:18411289
  Authors
Wasylnka JA, Bakowski MA, Szeto J, Ohlson MB, Trimble WS, Miller SI, Brumell JH
  Title
Role for myosin II in regulating positioning of Salmonella-containing vacuoles and intracellular replication.
  Journal
Infect Immun 76:2722-35 (2008)
DOI:10.1128/IAI.00152-08
Reference
PMID:10499590
  Authors
Fu Y, Galan JE
  Title
A salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion.
  Journal
Nature 401:293-7 (1999)
DOI:10.1038/45829
Related
pathway
padl04010  MAPK signaling pathway
padl04210  Apoptosis
padl04217  Necroptosis
padl04621  NOD-like receptor signaling pathway
KO pathway
ko05132   
LinkDB

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