KEGG ORTHOLOGY: K10608

ORTHOLOGY: K10608

Entry

K10608                      KO

Symbol

TRIM37, MUL

Name

tripartite motif-containing protein 37 [EC:2.3.2.27]

Pathway

map04120

Ubiquitin mediated proteolysis

Disease

H01289

Mulibrey nanism

Brite

KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    K10608  TRIM37, MUL; tripartite motif-containing protein 37
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K10608  TRIM37, MUL; tripartite motif-containing protein 37
Enzymes [BR:ko01000]
2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     K10608  TRIM37, MUL; tripartite motif-containing protein 37
Ubiquitin system [BR:ko04121]
Ubiquitin ligases (E3)
  Single Ring-finger type E3
   TRIM/RBCC proteins
    K10608  TRIM37, MUL; tripartite motif-containing protein 37

Genes

HSA:	4591(TRIM37)

PTR:	455163(TRIM37)

PPS:	100980647(TRIM37)

GGO:	101131673(TRIM37)

PON:	100435296(TRIM37)

PPYG:

129017389(TRIM37)

NLE:	100583751(TRIM37)

HMH:	116474408(TRIM37)

SSYN:

129470599(TRIM37)

MCC:	710934(TRIM37)

MCF:	102141097(TRIM37)

MTHB:

126939371

MNI:	105476833(TRIM37)

CSAB:

103242834(TRIM37)

CATY:

105583398(TRIM37)

PANU:

101017695(TRIM37)

TGE:	112610055(TRIM37)

MLEU:

105539130(TRIM37)

RRO:	104672959(TRIM37)

RBB:	108521624(TRIM37)

TFN:	117067309(TRIM37)

PTEH:

111537640(TRIM37)

CANG:

105520158(TRIM37)

CJC:	100403783(TRIM37)

SBQ:	101027755(TRIM37)

CIMI:

108312030(TRIM37)

ANAN:

105712449(TRIM37)

CSYR:

103270761(TRIM37)

MMUR:

105872804(TRIM37)

LCAT:

123620416(TRIM37)

PCOQ:

105813677(TRIM37)

OGA:	100941587(TRIM37)

MMU:	68729(Trim37)

MCAL:

110304539(Trim37)

MPAH:

110331513(Trim37)

RNO:	360592(Trim37)

MCOC:

116077431(Trim37)

ANU:	117710768(Trim37)

ASYL:

127695472(Trim37)

MUN:	110540066(Trim37)

CGE:	100754889(Trim37)

MAUA:

101837978(Trim37)

PROB:

127225221(Trim37)

PLEU:

114699269(Trim37)

PMAV:

102925392(Trim37)

MORG:

121456401(Trim37)

MFOT:

126486978

AAMP:

119811803(Trim37)

NGI:	103741774(Trim37)

HGL:	101716732(Trim37)

CPOC:

100714025(Trim37)

CCAN:

109686750(Trim37)

DORD:

105983248(Trim37)

DSP:	122117143(Trim37)

DMER:

138830601(Trim37)

PLOP:

125366423(Trim37)

NCAR:

124978907

MMMA:

107150393(Trim37)

ITI:	101960849(Trim37)

OCU:

100353301

OPI:	101531455(TRIM37)

OCZ:	121169689(TRIM37)

TUP:	102469329(TRIM37)

GVR:	103583304 103598675

CFA:	480575(TRIM37)

CLUD:

112655669(TRIM37)

VVP:	112917929(TRIM37)

VLG:	121472823(TRIM37)

NPO:	129504562(TRIM37)

AML:	100467093(TRIM37)

UMR:	103667343(TRIM37)

UAH:	113268881(TRIM37)

UAR:	123777083(TRIM37)

ELK:

111151430

LLV:

125088033

MPUF:

101684102(TRIM37)

MNP:	132004293(TRIM37)

MLK:	131816509(TRIM37)

NVS:	122906520(TRIM37)

ORO:	101384405(TRIM37)

EJU:	114213832(TRIM37)

ZCA:	113939361(TRIM37)

MLX:	118024692(TRIM37)

NSU:	110593149(TRIM37)

LWW:	102748851(TRIM37)

FCA:	101095387(TRIM37)

PYU:	121044708(TRIM37)

PCOO:

112854818(TRIM37)

PBG:	122485313(TRIM37)

PVIV:

125151425(TRIM37)

LRUF:

124513182

LGF:	123603379(TRIM37)

AJU:

106989950

PTG:	102955337(TRIM37)

PPAD:

109256113(TRIM37)

PUC:

125927422

PLEZ:

122206264(TRIM37)

HHV:	120241919(TRIM37)

BTA:	617078(TRIM37)

BOM:	102266195(TRIM37)

BIU:	109573166(TRIM37)

BBUB:

102414493(TRIM37)

BBIS:

105004094(TRIM37)

CHX:	102187429(TRIM37)

OAS:	101106605(TRIM37)

BTAX:

128064969(TRIM37)

CSUM:

138082880(TRIM37)

ODA:	120866441(TRIM37)

CCAD:

122450478(TRIM37)

MREE:

136149664(TRIM37)

OVR:	110142198(TRIM37)

MBEZ:

129539224(TRIM37)

SSC:	106505457(TRIM37)

CFR:	102512768(TRIM37)

CBAI:

105065859(TRIM37)

CDK:

105097816

VPC:	102542196(TRIM37)

BACU:

103018354(TRIM37)

BMUS:

118886542(TRIM37)

LVE:	103086598(TRIM37)

OOR:	101286368(TRIM37)

LALB:

132511128(TRIM37)

GMF:	115866340(TRIM37)

DDP:	132414617(TRIM37)

DLE:	111163747(TRIM37)

PCAD:

102983895(TRIM37)

PSIU:

116745482(TRIM37)

PPHC:

136137973(TRIM37)

NASI:

112408096(TRIM37)

ECB:	100057121(TRIM37)

EPZ:	103561736(TRIM37)

EAI:	106821770(TRIM37)

MYB:	102244567(TRIM37)

MYD:	102771022(TRIM37)

MMYO:

118671710(TRIM37)

MLF:	102436789(TRIM37)

MDT:	132218424(TRIM37)

MYUM:

138994961(TRIM37)

PKL:	118728072(TRIM37)

EFUS:

103291639(TRIM37)

MNA:	107535275(TRIM37)

DRO:	112316420(TRIM37)

SHON:

119003579(TRIM37)

AJM:	119062661(TRIM37)

PDIC:

114502590(TRIM37)

PHAS:

123817444(TRIM37)

MMF:	118633718(TRIM37)

PPAM:

129080186(TRIM37)

HAI:	109379790(TRIM37)

RFQ:	117014094(TRIM37)

PALE:

102886209(TRIM37)

PGIG:

120620811(TRIM37)

PVP:	105302114(TRIM37)

RAY:	107499155(TRIM37)

MJV:	108398499(TRIM37)

TOD:	119231685(TRIM37)

SARA:

101557612(TRIM37)

SFUM:

130035697(TRIM37)

SETR:

126007818(TRIM37)

LAV:	100657839(TRIM37)

TMU:

101358313

ETF:	101658677(TRIM37)

DNM:	101425438(TRIM37)

MDO:	100010737(TRIM37)

GAS:	123247701(TRIM37)

SHR:	100915944(TRIM37)

AFZ:

127559973

PCW:	110212060(TRIM37)

TVP:	118846218(TRIM37)

PBRV:

138153682(TRIM37)

MLAO:

141513607(TRIM37)

OAA:	100078358(TRIM37)

TACU:

119938982(TRIM37)

GGA:	417628(TRIM37)

PCOC:

116227972(TRIM37)

MGP:	100550103(TRIM37)

CJO:	107322515(TRIM37)

TPAI:

128083696(TRIM37)

LMUT:

125703111(TRIM37)

NMEL:

110407925(TRIM37)

APLA:

101795200(TRIM37)

ACYG:

106045802(TRIM37)

CATA:

118255019(TRIM37)

AFUL:

116497357(TRIM37)

TGU:	100225193(TRIM37)

LSR:	110467663(TRIM37)

SCAN:

103820163(TRIM37)

PMOA:

120507597(TRIM37)

OTC:	121347005(TRIM37)

PRUF:

121361594(TRIM37)

ATRC:

139600019(TRIM37)

GFR:	102038410(TRIM37)

FAB:	101814304(TRIM37)

OMA:	130261065(TRIM37)

PHI:	102102758(TRIM37)

PMAJ:

107212818(TRIM37)

CCAE:

111937824(TRIM37)

CCW:	104691011(TRIM37)

CBRC:

103613336(TRIM37)

ACOE:

138120484(TRIM37)

ETL:	114067717(TRIM37)

ZAB:

102065177

ZLE:	135455916(TRIM37)

ACHL:

103812045(TRIM37)

SVG:	106853415(TRIM37)

MMEA:

130585517(TRIM37)

HRT:	120761207(TRIM37)

SATI:

136370336(TRIM37)

CCIC:

134052688(TRIM37)

FPG:	101924329(TRIM37)

FCH:	102059122(TRIM37)

CCRI:

104158744(TRIM37)

NNT:	104405870(TRIM37)

SHAB:

115601820(TRIM37)

ACUN:

113487055(TRIM37)

TALA:

104366061(TRIM37)

ACHC:

115346911(TRIM37)

HALD:

104321112(TRIM37)

HLE:	104835649(TRIM37)

AGEN:

126039119

HHAR:

128149588(TRIM37)

GCL:

127024281

CSTI:

104558297(TRIM37)

LDI:	104344010(TRIM37)

MNB:	103772578(TRIM37)

DPUB:

104302719(TRIM37)

PPUS:

135187648(TRIM37)

AVIT:

104277683(TRIM37)

BRHI:

104502252(TRIM37)

EGZ:	104121890(TRIM37)

NNI:	104016632(TRIM37)

PCRI:

104029561(TRIM37)

PCAO:

104045415(TRIM37)

PADL:

103916761(TRIM37)

AFOR:

103898018(TRIM37)

FGA:	104079380(TRIM37)

CBOR:

142090495(TRIM37)

GSTE:

104254785(TRIM37)

CBOY:

140660830(TRIM37)

MAME:

142417248(TRIM37)

CLV:	102093588(TRIM37)

CNIC:

135995541(TRIM37)

MUI:	104548342(TRIM37)

PGUU:

104462950(TRIM37)

PLET:

104621302(TRIM37)

EHS:	104502780(TRIM37)

CMAC:

104484510(TRIM37)

CUCA:

104057169(TRIM37)

TEO:	104384165(TRIM37)

BREG:

104629365(TRIM37)

OHA:	104339623(TRIM37)

ACAR:

104527620(TRIM37)

CPEA:

104398912(TRIM37)

CVF:	104284367(TRIM37)

RTD:	128912322(TRIM37)

CRID:

134519024(TRIM37)

LMIC:

141746489(TRIM37)

AAM:	106500331(TRIM37)

AROW:

112968788(TRIM37)

NPD:	112954614(TRIM37)

TGT:	104570505(TRIM37)

DNE:	112983945(TRIM37)

SCAM:

104142780(TRIM37)

ASN:	102384993(TRIM37)

AMJ:	102568615(TRIM37)

CPOO:

109317182(TRIM37)

GGN:	109293301(TRIM37)

PSS:	102462735(TRIM37)

CIZ:	142023001(TRIM37)

CMY:	102931828(TRIM37)

CCAY:

125623750(TRIM37)

DCC:	119844585(TRIM37)

CPIC:

101946128(TRIM37)

TST:	117867355(TRIM37)

CABI:

116827405(TRIM37)

MRV:	120387333(TRIM37)

ACS:	100553676(trim37)

ASAO:

132763513(TRIM37)

PVT:	110075508(TRIM37)

SUND:

121916915(TRIM37)

PBI:	103060416(TRIM37)

PMUR:

107295180

CTIG:

120319565(TRIM37)

TSR:	106537520(TRIM37)

PGUT:

117656198(TRIM37)

PCAE:

139308462(TRIM37)

APRI:

131188659(TRIM37)

PTEX:

113442570(TRIM37)

NSS:	113424682(TRIM37)

VKO:	123023403(TRIM37)

PMUA:

114585256(TRIM37)

PRAF:

128402617(TRIM37)

ZVI:	118097145(TRIM37)

HCG:	128336019(TRIM37)

GJA:	107121281(TRIM37)

STOW:

125445814(TRIM37)

EMC:	129344750(TRIM37)

XLA:	108708315(trim37.L) 108709630(trim37.S)

XTR:	100036717(trim37)

NPR:	108791286(TRIM37)

RTEM:

120926686(TRIM37)

ACAT:

141128092(TRIM37)

PADS:

140334265(TRIM37)

BBUF:

120995501(TRIM37)

BGAR:

122931033(TRIM37)

DTC:	141088297(TRIM37)

PWL:	138285896(TRIM37)

MUO:	115482535(TRIM37)

GSH:	117348955(TRIM37)

DRE:	324237(trim37)

SRX:	107728810 107734467

SANH:

107686133 107691657

SGH:	107577452 107589414

CCAR:

109072272 109088281(trim37)

CAUA:

113054411 113109928(trim37)

CGIB:

127966776 128021085

PTET:

122353229(trim37)

LROH:

127172327(trim37)

GRF:	141299171(trim37)

OMC:	131548582(trim37)

PPRM:

120482371(trim37)

RKG:	130105501(trim37)

MAMB:

125262210(trim37)

CIDE:

127520083

CERY:

137029605(trim37)

MASI:

127432899 127433993

TROS:

130546231(trim37)

TDW:	130412144(trim37)

MANU:

129446825(trim37)

PDAB:

135741133(trim37)

IPU:

108277255

IFU:	128619972(trim37)

PHYP:

113524171(trim37)

SMEO:

124393734(trim37)

TFD:	113650269(trim37)

TVC:	132863446(trim37)

CGAR:

128505635(trim37)

NGRA:

132873681(trim37)

TRN:	134332187(trim37)

AMEX:

103041312(trim37)

CMAO:

118824981(trim37)

EEE:	113592017(trim37)

CHAR:

105909781(trim37)

SPIL:

134080651(trim37)

ASAD:

121708779(trim37)

TRU:	101071055(trim37)

TFS:	130537700(trim37)

TNG:	GSTEN00014650G001

LCO:	104918961(trim37)

TBEN:

117490739(trim37)

CGOB:

115018621 115018807

PGEO:

117458450(trim37)

GACU:

117548931(trim37)

EMAC:

134872546(trim37)

ELY:	117270791(trim37)

EFO:	125898248(trim37)

PLEP:

121952455(trim37)

SLUC:

116055968(trim37)

ECRA:

117955763(trim37)

ESP:	116701102(trim37)

PFLV:

114566831(trim37)

GAT:	120822436(trim37)

PPUG:

119215695(trim37)

AFB:	129113435(trim37)

CLUM:

117742616(trim37)

PSWI:

130190895(trim37)

CANA:

137802485(trim37)

CVE:	137890767(trim37)

MSAM:

119895589(trim37)

SCHU:

122887958(trim37)

CUD:	121518727(trim37)

SPUL:

138603235(trim37)

LMIX:

132988842(trim37)

HTC:	141791518(trim37)

ALAT:

119031099(trim37)

ASTR:

137606183(trim37)

MZE:	101483118(trim37)

ONL:	100694884(trim37)

OAU:	116319032(trim37)

OLA:	101162547(trim37)

OML:	112143024(trim37)

CSAI:

133460063(trim37)

XMA:	102224027(trim37)

XCO:	114153129(trim37)

XHE:	116728324(trim37)

PRET:

103476371(trim37)

PFOR:

103130777

PLAI:

106938516

PMEI:

106933418(trim37)

GAF:	122845342(trim37)

PPRL:

129353994(trim37)

CVG:	107098404(trim37)

CTUL:

119798133(trim37)

GMU:	124876375(trim37)

NFU:	107386632(trim37)

KMR:	108238099(trim37)

ALIM:

106530604(trim37)

NWH:	119420466(trim37)

AOCE:

111568603(trim37)

EJA:	138196077(trim37)

BFRE:

138627335(trim37)

MCEP:

125020840(trim37)

CSEM:

103395070(trim37)

POV:	109628729(trim37)

SSEN:

122779496(trim37)

SSOE:

131458793(trim37)

HHIP:

117774205(trim37)

HSP:	118122417(trim37)

PPLT:

128457203(trim37)

SMAU:

118300384(trim37)

LCF:

108893895

SDU:	111234488(trim37)

SLAL:

111648637 111666169 111671844

XGL:	120802381(trim37)

HCQ:	109516803(trim37)

SSCV:

125982022(trim37)

SBIA:

133491745(trim37)

PEE:	133415556(trim37)

PTAO:

133467183(trim37)

BPEC:

110170318(trim37)

ENY:	140361244(trim37)

MALB:

109959221(trim37)

BSPL:

114869617(trim37)

SJO:	128371596(trim37)

SSCO:

133994126(trim37)

TTY:	137195933(trim37)

GMH:	115546941(trim37)

SASA:

106567666 106603466(trim37)

STRU:

115148793 115154261(trim37)

OTW:	112228524 112257924

OMY:	110534878 110537545

OGO:	123999393 124011193

ONE:	115105481 115135961(trim37)

OKI:	109872786(trim37) 109892796

OKE:	118390032 118391105

OMM:	135548663 135550747

OCLA:

139418205 139423160

SALP:

111950506(trim37) 111980820

SNH:	120030756 120057023

SFON:

129818459 129868363

CCLU:

121550179 121579388

ELS:	105011106(trim37)

OEP:	134039466(trim37)

SFM:	108928036(trim37)

PKI:	111847868(trim37)

AANG:

118236446(trim37)

AROT:

135263895(trim37)

CCOG:

133133816(trim37)

LOC:	102686854(trim37)

PSPA:

121308499(trim37)

ARUT:

117429172 117430275

PSEX:

120531438(trim37)

LCM:	102352623(TRIM37)

CMK:	103186917(trim37)

RTP:	125486182(trim37)

CPLA:

122563916(trim37)

CPUN:

140491582(trim37)

HOC:	132830286(trim37)

SCAU:

119974349(trim37)

LERI:

129710567(trim37)

HAKA:

140731610(trim37)

PMRN:

116950121(TRIM37)

LRJ:	133348949(TRIM37)

BFO:

118426607

BBEL:

109466324

CIN:	778844(zf(bbox/ring)-2)

SCLV:

SPU:

LPIC:

LVG:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:	100373529(TRIM37)

PFLL:

ECOE:

CLON:

HIS:

AGA:	1274040 4576818

ACOZ:

AARA:

ASTE:

AMAP:

AMRS:

ACOS:

AAG:	110680385 5563854 5565917 5567550 5576280 5576649

AALB:

109401686 109413687 109414473 109418285 109420030 109420298 109622270 115257487 115266420

ASUA:

134211846 134217225 134218106 134220198 134227068

CQU:	CpipJ_CPIJ000278 CpipJ_CPIJ001213 CpipJ_CPIJ009165 CpipJ_CPIJ010192

CPII:

120426761 120431612 120432374

CBRI:

CNS:

BCOO:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

ACOC:

MZT:

CCOA:

TCZ:

TSEP:

PBAR:

VEM:

COBS:

TLN:

HST:

DQU:

CFO:

FEX:

PMEC:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

FAS:

DAM:

AGIF:

VCAN:

CCIN:

AROA:

TCA:

TMOL:

DPA:

ESIM:

EFOR:

SOY:

RFG:

ATD:	109603528 109603533

CSET:

HAXR:

AGB:

LDC:

DVV:	114328965 126889776

NVL:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_200134

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ONU:	135071671 135072120

ATRA:

GMW:

PGW:

LGLY:

CSTB:

CFUM:

CFEL:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

CLEC:

HHAL:

NLU:

LDA:

HVI:

MQU:

PHU:	Phum_PHUM125560

FOC:

TPAL:

ZNE:

CSEC:

PAME:

SGRE:

BROR:

IEL:

HAMR:

FCD:

DPX:	DAPPUDRAFT_312201

DMK:

DPZ:

PJA:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

MRJ:

PORN:

HAZT:

EAF:

LSM:

TCF:

PPOI:

DSV:

DALB:

RSAN:

RMP:

VDE:

VJA:

CSCU:

CVS:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

LGI:	LOTGIDRAFT_128738

PCAN:

LSAX:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

YBA:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:	115226655 118761862

LJP:

135476258

LAK:	106153512 106161360

SMM:	Smp_147520

OVI:	T265_07774

EGL:

LLON:

NVE:

EPA:

ATEN:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:	114520436 114538286

HMG:

100197314

RES:

135683193

TAD:	TRIADDRAFT_58319

AQU:

109583188

SMO:	SELMODRAFT_418725 SELMODRAFT_425390 SELMODRAFT_429827

PPP:	112280163 112281402 112290177

GSL:	Gasu_14950

TET:	TTHERM_00476630

PTM:	GSPATT00021059001 GSPATT00022963001

NGR:	NAEGRDRAFT_72663

TVA:	4749213(TVAGG3_0448090)

» show all

Reference

PMID:15885686

Authors

Kallijarvi J, Lahtinen U, Hamalainen R, Lipsanen-Nyman M, Palvimo JJ, Lehesjoki AE

Title

TRIM37 defective in mulibrey nanism is a novel RING finger ubiquitin E3 ligase.

Journal

Exp Cell Res 308:146-55 (2005)
DOI:10.1016/j.yexcr.2005.04.001

Sequence

[hsa:4591]

LinkDB

DBGET integrated database retrieval system