KEGG   PATHWAY: stru04520
Entry
stru04520                   Pathway                                
Name
Adherens junction - Salmo trutta (river trout)
Description
Cell-cell adherens junctions (AJs), the most common type of intercellular adhesions, are important for maintaining tissue architecture and cell polarity and can limit cell movement and proliferation. At AJs, E-cadherin serves as an essential cell adhesion molecules (CAMs). The cytoplasmic tail binds beta-catenin, which in turn binds alpha-catenin. Alpha-catenin is associated with F-actin bundles directly and indirectly. The integrity of the cadherin-catenin complex is negatively regulated by phosphorylation of beta-catenin by receptor tyrosine kinases (RTKs) and cytoplasmic tyrosine kinases (Fer, Fyn, Yes, and Src), which leads to dissociation of the cadherin-catenin complex. Integrity of this complex is positively regulated by beta -catenin phosphorylation by casein kinase II, and dephosphorylation by protein tyrosine phosphatases. Changes in the phosphorylation state of beta-catenin affect cell-cell adhesion, cell migration and the level of signaling beta-catenin. Wnt signaling acts as a positive regulator of beta-catenin by inhibiting beta-catenin degradation, which stabilizes beta-catenin, and causes its accumulation. Cadherin may acts as a negative regulator of signaling beta-catenin as it binds beta-catenin at the cell surface and thereby sequesters it from the nucleus. Nectins also function as CAMs at AJs, but are more highly concentrated at AJs than E-cadherin. Nectins transduce signals through Cdc42 and Rac, which reorganize the actin cytoskeleton, regulate the formation of AJs, and strengthen cell-cell adhesion.
Class
Cellular Processes; Cellular community - eukaryotes
Pathway map
stru04520  Adherens junction
stru04520

Other DBs
GO: 0005912
Organism
Salmo trutta (river trout) [GN:stru]
Gene
115153786  nectin-1-like isoform X1 [KO:K06081]
115163869  nectin-1-like [KO:K06081]
115206737  nectin-1-like [KO:K06081]
115180632  poliovirus receptor-like isoform X1 [KO:K06531]
115176381  nectin-2-like [KO:K06531]
115173533  poliovirus receptor-like isoform X1 [KO:K06531]
115175936  poliovirus receptor-like isoform X1 [KO:K06531]
115154500  nectin-3-like protein [KO:K06592]
115163396  nectin-3-like protein [KO:K06592]
115149038  nectin-3-like protein isoform X1 [KO:K06592]
115206320  nectin-3-like protein [KO:K06592]
115169513  nectin-4-like isoform X1 [KO:K06593]
115157282  nectin-4-like [KO:K06593]
115194302  nectin-4-like [KO:K06593]
115198310  nectin-4-like [KO:K06593]
115169829  partitioning defective 3 homolog isoform X1 [KO:K04237]
115153707  partitioning defective 3 homolog isoform X1 [KO:K04237]
115156868  partitioning defective 3 homolog isoform X1 [KO:K04237]
115167934  proto-oncogene tyrosine-protein kinase Src isoform X1 [KO:K05704] [EC:2.7.10.2]
115165589  proto-oncogene tyrosine-protein kinase Src-like isoform X1 [KO:K05704] [EC:2.7.10.2]
115150079  proto-oncogene tyrosine-protein kinase Src-like isoform X1 [KO:K05704] [EC:2.7.10.2]
115208382  proto-oncogene tyrosine-protein kinase Src-like isoform X1 [KO:K05704] [EC:2.7.10.2]
115158868  farp2; FERM, ARHGEF and pleckstrin domain-containing protein 2 isoform X1 [KO:K06082]
115168105  cell division control protein 42 homolog isoform X1 [KO:K04393]
115185212  cell division control protein 42 homolog [KO:K04393]
115188175  cell division control protein 42 homolog [KO:K04393]
115175951  cell division control protein 42 homolog [KO:K04393]
115165776  cell division control protein 42 homolog isoform X1 [KO:K04393]
115177487  cell division control protein 42 homolog [KO:K04393]
115173517  cell division control protein 42 homolog isoform X1 [KO:K04393]
115150657  cell division control protein 42 homolog isoform X1 [KO:K04393]
115152908  ras-related C3 botulinum toxin substrate 1 [KO:K04392]
115171654  ras-related C3 botulinum toxin substrate 1-like isoform X1 [KO:K04392]
115201416  ras-related C3 botulinum toxin substrate 1 [KO:K04392]
115205281  ras-related C3 botulinum toxin substrate 1-like isoform X1 [KO:K04392]
115171460  ras-related C3 botulinum toxin substrate 2 isoform X1 [KO:K07860]
115147435  ras-related C3 botulinum toxin substrate 2-like [KO:K07860]
115202895  ras-related C3 botulinum toxin substrate 2-like [KO:K07860]
115152909  ras-related C3 botulinum toxin substrate 3-like isoform X1 [KO:K07861]
115171935  ras-related C3 botulinum toxin substrate 3-like [KO:K07861]
115201417  rac3; ras-related C3 botulinum toxin substrate 3 isoform X1 [KO:K07861]
115208641  ras-related C3 botulinum toxin substrate 3-like [KO:K07861]
115180630  neural Wiskott-Aldrich syndrome protein-like isoform X1 [KO:K23612]
115192732  neural Wiskott-Aldrich syndrome protein-like [KO:K23612]
115197027  neural Wiskott-Aldrich syndrome protein-like isoform X1 [KO:K23612]
115198756  neural Wiskott-Aldrich syndrome protein-like isoform X1 [KO:K23612]
115150546  neural Wiskott-Aldrich syndrome protein-like isoform X1 [KO:K23612]
115168088  wiskott-Aldrich syndrome protein-like [KO:K05747]
115165753  was; wiskott-Aldrich syndrome protein isoform X1 [KO:K05747]
115166923  ras GTPase-activating-like protein IQGAP1 [KO:K16848]
115203385  ras GTPase-activating-like protein IQGAP1 [KO:K16848]
115189126  brain-specific angiogenesis inhibitor 1-associated protein 2-like isoform X1 [KO:K05627]
115153508  brain-specific angiogenesis inhibitor 1-associated protein 2-like isoform X1 [KO:K05627]
115176805  brain-specific angiogenesis inhibitor 1-associated protein 2-like isoform X1 [KO:K05627]
115171883  brain-specific angiogenesis inhibitor 1-associated protein 2-like isoform X1 [KO:K05627]
115201684  brain-specific angiogenesis inhibitor 1-associated protein 2-like isoform X1 [KO:K05627]
115208011  brain-specific angiogenesis inhibitor 1-associated protein 2-like isoform X1 [KO:K05627]
115174438  wiskott-Aldrich syndrome protein family member 1-like isoform X1 [KO:K05753]
115177424  wasf1; wiskott-Aldrich syndrome protein family member 1 [KO:K05753]
115173848  wasf2; wiskott-Aldrich syndrome protein family member 2 [KO:K05748]
115185805  LOW QUALITY PROTEIN: wiskott-Aldrich syndrome protein family member 2-like [KO:K05748]
115154798  wiskott-Aldrich syndrome protein family member 3-like isoform X1 [KO:K06083]
115154862  wiskott-Aldrich syndrome protein family member 3-like [KO:K06083]
115151204  wiskott-Aldrich syndrome protein family member 3-like [KO:K06083]
115195485  wiskott-Aldrich syndrome protein family member 3-like isoform X1 [KO:K06083]
115204402  wiskott-Aldrich syndrome protein family member 3-like isoform X1 [KO:K06083]
115204481  wiskott-Aldrich syndrome protein family member 3-like [KO:K06083]
115193037  afdn; afadin isoform X1 [KO:K05702]
115174826  afadin-like [KO:K05702]
115172057  afadin-like [KO:K05702]
115156246  LIM domain only protein 7-like isoform X1 [KO:K06084]
115160588  LIM domain only protein 7-like isoform X1 [KO:K06084]
115157927  ssx2ip; afadin- and alpha-actinin-binding protein isoform X1 [KO:K06085]
115169548  afadin- and alpha-actinin-binding protein-like isoform X1 [KO:K06085]
115157230  afadin- and alpha-actinin-binding protein-like [KO:K06085]
115207162  afadin- and alpha-actinin-binding protein-like isoform X1 [KO:K06085]
115193998  sorbin and SH3 domain-containing protein 1-like isoform X1 [KO:K06086]
115153011  sorbs1; sorbin and SH3 domain-containing protein 1 [KO:K06086]
115163178  alpha-actinin-4-like isoform X1 [KO:K05699]
115172169  alpha-actinin-1 [KO:K05699]
115206123  alpha-actinin-4 isoform X1 [KO:K05699]
115153530  vcl; vinculin isoform X1 [KO:K05700]
115153616  vinculin-like isoform X1 [KO:K05700]
115200894  vinculin-like [KO:K05700]
115192877  tight junction protein ZO-1-like isoform X1 [KO:K05701]
115167354  tight junction protein ZO-1-like isoform X1 [KO:K05701]
115202998  tight junction protein ZO-1-like isoform X1 [KO:K05701]
115196557  tight junction protein ZO-1-like isoform X1 [KO:K05701]
115167390  B-cadherin-like isoform X1 [KO:K05689]
115202968  B-cadherin-like [KO:K05689]
115190080  catenin delta-1-like isoform X1 [KO:K05690]
115171748  catenin delta-1-like isoform X1 [KO:K05690]
115202447  catenin delta-1-like isoform X1 [KO:K05690]
115205187  catenin delta-1-like isoform X1 [KO:K05690]
115185143  catenin beta-1 isoform X1 [KO:K02105]
115177148  catenin beta-1-like isoform X1 [KO:K02105]
115192023  catenin alpha-2-like [KO:K05691]
115166529  catenin alpha-1 isoform X1 [KO:K05691]
115202084  catenin alpha-2 [KO:K05691]
115205764  catenin alpha-1-like [KO:K05691]
115188892  actin, cytoplasmic 1 [KO:K05692]
115188893  actin, cytoplasmic 1 [KO:K05692]
115168240  rho-related GTP-binding protein RhoA-C [KO:K04513]
115168296  rho-related GTP-binding protein RhoA-B-like [KO:K04513]
115165260  rho-related GTP-binding protein RhoA-C-like [KO:K04513]
115165905  rho-related GTP-binding protein RhoA-C-like isoform X1 [KO:K04513]
115166252  rho-related GTP-binding protein RhoA-B [KO:K04513]
115150994  rho-related GTP-binding protein RhoA-D [KO:K04513]
115150254  transforming protein RhoA-like [KO:K04513]
115208179  transforming protein RhoA-like [KO:K04513]
115184182  acp1; low molecular weight phosphotyrosine protein phosphatase isoform X1 [KO:K14394] [EC:3.1.3.2 3.1.3.48]
115169218  receptor-type tyrosine-protein phosphatase mu-like [KO:K05693] [EC:3.1.3.48]
115156479  receptor-type tyrosine-protein phosphatase mu-like [KO:K05693] [EC:3.1.3.48]
115150117  receptor-type tyrosine-protein phosphatase mu-like isoform X1 [KO:K05693] [EC:3.1.3.48]
115195565  receptor-type tyrosine-protein phosphatase mu-like isoform X1 [KO:K05693] [EC:3.1.3.48]
115152314  receptor-type tyrosine-protein phosphatase beta-like [KO:K05694] [EC:3.1.3.48]
115189966  receptor-type tyrosine-protein phosphatase beta-like [KO:K05694] [EC:3.1.3.48]
115197532  receptor-type tyrosine-protein phosphatase beta-like isoform X1 [KO:K05694] [EC:3.1.3.48]
115185025  receptor-type tyrosine-protein phosphatase F-like [KO:K05695] [EC:3.1.3.48]
115192316  receptor-type tyrosine-protein phosphatase F-like isoform X1 [KO:K05695] [EC:3.1.3.48]
115158605  receptor-type tyrosine-protein phosphatase F-like [KO:K05695] [EC:3.1.3.48]
115168033  tyrosine-protein phosphatase non-receptor type 1-like [KO:K05696] [EC:3.1.3.48]
115165688  tyrosine-protein phosphatase non-receptor type 1-like [KO:K05696] [EC:3.1.3.48]
115187775  tyrosine-protein phosphatase non-receptor type 6-like isoform X1 [KO:K05697] [EC:3.1.3.48]
115177393  tyrosine-protein phosphatase non-receptor type 6-like isoform X1 [KO:K05697] [EC:3.1.3.48]
115192769  titin-like isoform X1 [KO:K05698] [EC:3.1.3.48]
115197043  receptor-type tyrosine-protein phosphatase eta-like [KO:K05698] [EC:3.1.3.48]
115185756  casein kinase II subunit alpha-like [KO:K03097] [EC:2.7.11.1]
115174049  casein kinase II subunit alpha-like isoform X1 [KO:K03097] [EC:2.7.11.1]
115175558  casein kinase II subunit alpha [KO:K03097] [EC:2.7.11.1]
115176623  casein kinase II subunit alpha-like [KO:K03097] [EC:2.7.11.1]
115166713  casein kinase II subunit alpha'-like isoform X1 [KO:K03097] [EC:2.7.11.1]
115151855  casein kinase II subunit alpha' isoform X1 [KO:K03097] [EC:2.7.11.1]
115150132  casein kinase II subunit alpha-like [KO:K03097] [EC:2.7.11.1]
115208343  casein kinase II subunit alpha isoform X1 [KO:K03097] [EC:2.7.11.1]
115196912  casein kinase II subunit alpha'-like isoform X1 [KO:K03097] [EC:2.7.11.1]
115203596  casein kinase II subunit alpha'-like [KO:K03097] [EC:2.7.11.1]
115185845  casein kinase II subunit beta-like isoform X1 [KO:K03115]
115176017  casein kinase II subunit beta [KO:K03115]
115176651  casein kinase II subunit beta-like isoform X1 [KO:K03115]
115173331  casein kinase II subunit beta isoform X1 [KO:K03115]
115154022  lymphoid enhancer-binding factor 1-like isoform X1 [KO:K02620]
115148559  lymphoid enhancer-binding factor 1-like isoform X1 [KO:K02620]
115159747  transcription factor 7-like 1-B isoform X1 [KO:K04490]
115164508  transcription factor 7-like 1-B isoform X1 [KO:K04490]
115203917  transcription factor 7-like 1-B isoform X1 [KO:K04490]
115200136  transcription factor 7-like 1-B isoform X1 [KO:K04490]
115158068  transcription factor 7-like 2 isoform X1 [KO:K04491]
115201081  transcription factor 7-like 2 isoform X1 [KO:K04491]
115191730  lef1; lymphoid enhancer-binding factor 1 isoform X1 [KO:K04492]
115182685  insulin-like growth factor 1 receptor [KO:K05087] [EC:2.7.10.1]
115151978  insulin-like growth factor 1 receptor [KO:K05087] [EC:2.7.10.1]
115196778  insulin-like growth factor 1 receptor [KO:K05087] [EC:2.7.10.1]
115203659  insulin-like growth factor 1 receptor isoform X1 [KO:K05087] [EC:2.7.10.1]
115157526  insulin receptor-like isoform X1 [KO:K04527] [EC:2.7.10.1]
115192162  insulin receptor-like [KO:K04527] [EC:2.7.10.1]
115169288  insulin receptor-like [KO:K04527] [EC:2.7.10.1]
115158830  insulin receptor-like isoform X1 [KO:K04527] [EC:2.7.10.1]
115152322  hepatocyte growth factor receptor-like [KO:K05099] [EC:2.7.10.1]
115197549  hepatocyte growth factor receptor-like isoform X1 [KO:K05099] [EC:2.7.10.1]
115169555  epidermal growth factor receptor-like [KO:K04361] [EC:2.7.10.1]
115157224  epidermal growth factor receptor-like isoform X1 [KO:K04361] [EC:2.7.10.1]
115150387  melanoma receptor tyrosine-protein kinase-like isoform X1 [KO:K04361] [EC:2.7.10.1]
115195550  melanoma receptor tyrosine-protein kinase-like [KO:K04361] [EC:2.7.10.1]
115162108  erbb2; receptor tyrosine-protein kinase erbB-2 [KO:K05083] [EC:2.7.10.1]
115159756  fibroblast growth factor receptor 1-A-like isoform X1 [KO:K04362] [EC:2.7.10.1]
115164552  fibroblast growth factor receptor 1-A-like isoform X1 [KO:K04362] [EC:2.7.10.1]
115203912  fibroblast growth factor receptor 1-A-like isoform X1 [KO:K04362] [EC:2.7.10.1]
115200093  fibroblast growth factor receptor 1-A-like isoform X1 [KO:K04362] [EC:2.7.10.1]
115159218  tyrosine-protein kinase Fer-like isoform X1 [KO:K08889] [EC:2.7.10.2]
115149333  tyrosine-protein kinase Fer-like isoform X1 [KO:K08889] [EC:2.7.10.2]
115194124  tyrosine-protein kinase Fyn isoform X1 [KO:K05703] [EC:2.7.10.2]
115190053  tyrosine-protein kinase Fyn-like isoform X1 [KO:K05703] [EC:2.7.10.2]
115154525  tyrosine-protein kinase Yes-like [KO:K05705] [EC:2.7.10.2]
115195795  tyrosine-protein kinase yes [KO:K05705] [EC:2.7.10.2]
115165075  mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
115192138  mitogen-activated protein kinase 1-like [KO:K04371] [EC:2.7.11.24]
115170800  mitogen-activated protein kinase 1-like [KO:K04371] [EC:2.7.11.24]
115200671  mitogen-activated protein kinase 1-like [KO:K04371] [EC:2.7.11.24]
115169603  zinc finger protein SNAI2-like [KO:K05706]
115157173  zinc finger protein SNAI2-like [KO:K05706]
115168526  protein snail homolog Sna-like isoform X1 [KO:K05707]
115150832  protein snail homolog Sna-like [KO:K05707]
115207599  protein snail homolog Sna-like [KO:K05707]
115169694  TGF-beta receptor type-1-like isoform X1 [KO:K04674] [EC:2.7.11.30]
115157085  TGF-beta receptor type-1-like [KO:K04674] [EC:2.7.11.30]
115149427  TGF-beta receptor type-1 isoform X1 [KO:K04674] [EC:2.7.11.30]
115195639  TGF-beta receptor type-1-like isoform X1 [KO:K04674] [EC:2.7.11.30]
115176037  TGF-beta receptor type-2-like isoform X1 [KO:K04388] [EC:2.7.11.30]
115155646  TGF-beta receptor type-2-like [KO:K04388] [EC:2.7.11.30]
115160989  TGF-beta receptor type-2-like [KO:K04388] [EC:2.7.11.30]
115173307  TGF-beta receptor type-2-like [KO:K04388] [EC:2.7.11.30]
115192958  smad3; mothers against decapentaplegic homolog 3 [KO:K23605]
115166794  mothers against decapentaplegic homolog 3 [KO:K23605]
115164984  smad4; LOW QUALITY PROTEIN: mothers against decapentaplegic homolog 4 [KO:K04501]
115173628  mothers against decapentaplegic homolog 4-like isoform X1 [KO:K04501]
115175837  mothers against decapentaplegic homolog 4-like isoform X1 [KO:K04501]
115176558  mothers against decapentaplegic homolog 4-like isoform X1 [KO:K04501]
115159360  mothers against decapentaplegic homolog 4-like isoform X1 [KO:K04501]
115180008  mothers against decapentaplegic homolog 4-like isoform X1 [KO:K04501]
115149222  mothers against decapentaplegic homolog 4-like isoform X1 [KO:K04501]
115199711  mothers against decapentaplegic homolog 4-like [KO:K04501]
115152698  histone acetyltransferase p300-like [KO:K04498] [EC:2.3.1.48]
115171283  histone acetyltransferase p300-like isoform X1 [KO:K04498] [EC:2.3.1.48]
115171774  CREB-binding protein-like isoform X1 [KO:K04498] [EC:2.3.1.48]
115178827  CREB-binding protein-like isoform X1 [KO:K04498] [EC:2.3.1.48]
115147398  CREB-binding protein-like isoform X1 [KO:K04498] [EC:2.3.1.48]
115206430  CREB-binding protein-like isoform X1 [KO:K04498] [EC:2.3.1.48]
115201319  histone acetyltransferase p300-like isoform X1 [KO:K04498] [EC:2.3.1.48]
115199931  histone acetyltransferase p300-like [KO:K04498] [EC:2.3.1.48]
115174914  mitogen-activated protein kinase kinase kinase 7-like isoform X1 [KO:K04427] [EC:2.7.11.25]
115162495  mitogen-activated protein kinase kinase kinase 7-like [KO:K04427] [EC:2.7.11.25]
115172787  mitogen-activated protein kinase kinase kinase 7-like [KO:K04427] [EC:2.7.11.25]
115194264  map3k7; mitogen-activated protein kinase kinase kinase 7 isoform X1 [KO:K04427] [EC:2.7.11.25]
115192155  serine/threonine-protein kinase NLK2-like [KO:K04468] [EC:2.7.11.24]
115170822  serine/threonine-protein kinase NLK2-like [KO:K04468] [EC:2.7.11.24]
115163594  serine/threonine-protein kinase NLK [KO:K04468] [EC:2.7.11.24]
115206491  serine/threonine-protein kinase NLK-like [KO:K04468] [EC:2.7.11.24]
115167408  cadherin-5-like [KO:K06533]
115202911  cadherin-5-like [KO:K06533]
115160984  protein HEG-like isoform X1 [KO:K24472]
115155643  protein HEG-like isoform X1 [KO:K24472]
115173679  krit1; krev interaction trapped protein 1 [KO:K17705]
115175796  krev interaction trapped protein 1-like isoform X1 [KO:K17705]
115175186  ccm2; cerebral cavernous malformations 2 protein isoform X1 [KO:K26416]
115183983  programmed cell death protein 10-like [KO:K18269]
115163741  programmed cell death protein 10 [KO:K18269]
115196181  programmed cell death protein 10-B-like [KO:K18269]
115183943  E3 ubiquitin-protein ligase SMURF1-like isoform X1 [KO:K04678] [EC:2.3.2.26]
115188858  E3 ubiquitin-protein ligase SMURF1-like isoform X1 [KO:K04678] [EC:2.3.2.26]
115188928  E3 ubiquitin-protein ligase SMURF1-like isoform X1 [KO:K04678] [EC:2.3.2.26]
115171382  E3 ubiquitin-protein ligase SMURF2-like isoform X1 [KO:K04678] [EC:2.3.2.26]
115178351  E3 ubiquitin-protein ligase SMURF2-like isoform X1 [KO:K04678] [EC:2.3.2.26]
115201867  E3 ubiquitin-protein ligase SMURF2 [KO:K04678] [EC:2.3.2.26]
115208608  E3 ubiquitin-protein ligase SMURF2-like isoform X1 [KO:K04678] [EC:2.3.2.26]
115168039  ras-related protein O-Krev isoform X1 [KO:K04353]
115165695  ras-related protein Rap-1A-like [KO:K04353]
115150983  ras-related protein Rap-1A-like [KO:K04353]
115207441  ras-related protein Rap-1A-like [KO:K04353]
115182047  ras-related protein Rap-1b [KO:K07836]
115182953  ras-related protein Rap-1b-like [KO:K07836]
115176356  ras-interacting protein 1-like [KO:K26417]
115188403  ras-interacting protein 1-like [KO:K26417]
115178666  ras-associating and dilute domain-containing protein-like [KO:K26418]
115202866  ras-associating and dilute domain-containing protein-like isoform X1 [KO:K26418]
115183497  ras-associating and dilute domain-containing protein-like [KO:K26418]
115171456  ras-associating and dilute domain-containing protein-like isoform X1 [KO:K26418]
115201296  ras-interacting protein 1-like isoform X1 [KO:K26418]
115183498  ras-associating and dilute domain-containing protein-like [KO:K26418]
115157594  LOW QUALITY PROTEIN: rho GTPase-activating protein 29-like [KO:K20644]
115153083  rho GTPase-activating protein 29-like isoform X1 [KO:K20644]
115170194  rho GTPase-activating protein 29-like isoform X1 [KO:K20644]
115195349  rho GTPase-activating protein 29-like isoform X1 [KO:K20644]
115169563  rho-associated protein kinase 1-like isoform X1 [KO:K04514] [EC:2.7.11.1]
115157216  rho-associated protein kinase 1-like isoform X1 [KO:K04514] [EC:2.7.11.1]
115175052  rho-associated protein kinase 2-like isoform X1 [KO:K17388] [EC:2.7.11.1]
115162175  rho-associated protein kinase 2-like isoform X1 [KO:K17388] [EC:2.7.11.1]
115172456  rho-associated protein kinase 2-like isoform X1 [KO:K17388] [EC:2.7.11.1]
115195645  rho-associated protein kinase 2-like [KO:K17388] [EC:2.7.11.1]
115149859  myosin regulatory light chain 2, ventricular/cardiac muscle isoform-like [KO:K10351]
115208045  myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351]
115160260  myosin light chain 5-like [KO:K12753]
115164223  myosin regulatory light chain 2, atrial isoform-like [KO:K12754]
115200420  myosin regulatory light chain 2, atrial isoform-like [KO:K12754]
115150175  myosin regulatory light polypeptide 9 [KO:K12755]
115208297  myosin regulatory light polypeptide 9 [KO:K12755]
115154273  myosin regulatory light chain 2, ventricular/cardiac muscle isoform-like [KO:K12756]
115148801  myosin regulatory light chain 2, ventricular/cardiac muscle isoform-like [KO:K12756]
115154593  myosin regulatory light polypeptide 9-like [KO:K12757]
115195786  myosin regulatory light polypeptide 9 [KO:K12757]
115171514  myosin regulatory light chain 2, skeletal muscle isoform type 2-like [KO:K12758]
115203748  myosin regulatory light chain 2, skeletal muscle isoform type 2-like [KO:K12758]
115200285  myosin regulatory light chain 2, skeletal muscle isoform-like [KO:K12758]
Reference
PMID:15001769
  Authors
Nelson WJ, Nusse R.
  Title
Convergence of Wnt, beta-catenin, and cadherin pathways.
  Journal
Science 303:1483-7 (2004)
DOI:10.1126/science.1094291
Reference
PMID:10204118
  Authors
Potter E, Bergwitz C, Brabant G.
  Title
The cadherin-catenin system: implications for growth and differentiation of endocrine tissues.
  Journal
Endocr Rev 20:207-39 (1999)
DOI:10.1210/edrv.20.2.0362
Reference
PMID:10959047
  Authors
Beavon IR.
  Title
The E-cadherin-catenin complex in tumour metastasis: structure, function and regulation.
  Journal
Eur J Cancer 36:1607-20 (2000)
DOI:10.1016/S0959-8049(00)00158-1
Reference
PMID:15489912
  Authors
Reynolds AB, Roczniak-Ferguson A.
  Title
Emerging roles for p120-catenin in cell adhesion and cancer.
  Journal
Oncogene 23:7947-56 (2004)
DOI:10.1038/sj.onc.1208161
Reference
PMID:11171368
  Authors
Angst BD, Marcozzi C, Magee AI.
  Title
The cadherin superfamily: diversity in form and function.
  Journal
J Cell Sci 114:629-41 (2001)
Reference
PMID:11984870
  Authors
Lilien J, Balsamo J, Arregui C, Xu G.
  Title
Turn-off, drop-out: functional state switching of cadherins.
  Journal
Dev Dyn 224:18-29 (2002)
DOI:10.1002/dvdy.10087
Reference
PMID:12640114
  Authors
Piedra J, Miravet S, Castano J, Palmer HG, Heisterkamp N, Garcia de Herreros A, Dunach M.
  Title
p120 Catenin-associated Fer and Fyn tyrosine kinases regulate beta-catenin Tyr-142 phosphorylation and beta-catenin-alpha-catenin Interaction.
  Journal
Mol Cell Biol 23:2287-97 (2003)
DOI:10.1128/MCB.23.7.2287-2297.2003
Reference
PMID:14623871
  Authors
Conacci-Sorrell M, Simcha I, Ben-Yedidia T, Blechman J, Savagner P, Ben-Ze'ev A.
  Title
Autoregulation of E-cadherin expression by cadherin-cadherin interactions: the roles of beta-catenin signaling, Slug, and MAPK.
  Journal
J Cell Biol 163:847-57 (2003)
DOI:10.1083/jcb.200308162
Reference
PMID:11703922
  Authors
Ciruna B, Rossant J.
  Title
FGF signaling regulates mesoderm cell fate specification and morphogenetic movement at the primitive streak.
  Journal
Dev Cell 1:37-49 (2001)
DOI:10.1016/S1534-5807(01)00017-X
Reference
PMID:12665527
  Authors
Peinado H, Quintanilla M, Cano A.
  Title
Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions.
  Journal
J Biol Chem 278:21113-23 (2003)
DOI:10.1074/jbc.M211304200
Reference
PMID:10890911
  Authors
Labbe E, Letamendia A, Attisano L.
  Title
Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-beta and wnt pathways.
  Journal
Proc Natl Acad Sci U S A 97:8358-63 (2000)
DOI:10.1073/pnas.150152697
Reference
PMID:15551862
  Authors
Nakanishi H, Takai Y.
  Title
Roles of nectins in cell adhesion, migration and polarization.
  Journal
Biol Chem 385:885-92 (2004)
DOI:10.1515/BC.2004.116
Reference
PMID:15561584
  Authors
Irie K, Shimizu K, Sakisaka T, Ikeda W, Takai Y.
  Title
Roles and modes of action of nectins in cell-cell adhesion.
  Journal
Semin Cell Dev Biol 15:643-56 (2004)
DOI:10.1016/j.semcdb.2004.09.002
Related
pathway
stru04010  MAPK signaling pathway
stru04060  Cytokine-cytokine receptor interaction
stru04310  Wnt signaling pathway
stru04350  TGF-beta signaling pathway
stru04530  Tight junction
stru04810  Regulation of actin cytoskeleton
KO pathway
ko04520   
LinkDB

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