KEGG   DGROUP: CYP2C19 substrate
Entry
DG01639                     DGroup                                 

Name
CYP2C19 substrate
Member
Omeprazole
 D00455  
Omeprazole (JP17/USP/INN)  <JP/US>
 D01207  
Omeprazole sodium (USAN)
 D05261  
Omeprazole sodium injection (JAN)  <JP>
 D05259  
Omeprazole magnesium (USP)  <US>
Pantoprazole
 D05353  
Pantoprazole (USAN/INN)
 D02593  
Pantoprazole sodium (USP); Pantoprazole sodium hydrate (JAN)  <US>
D00355  
Lansoprazole (JP17/USP/INN)  <JP/US>
Rabeprazole
 D08463  
Rabeprazole (INN)
 D00724  
Rabeprazole sodium (JP17/USP)  <JP/US>
Esomeprazole
 D07917  
Esomeprazole (INN)
 D01984  
Esomeprazole magnesium (USP); Esomeprazole magnesium hydrate (JAN)  <JP/US>
 D04056  
Esomeprazole sodium (USAN)  <US>
 D09339  
Esomeprazole potassium (USAN)
 D10120  
Esomeprazole strontium (USAN)  <US>
 D11114  
Esomeprazole magnesium dihydrate  <US>
D08903  
Dexlansoprazole (INN/USAN)  <US>
D09742  
Lansoprazole, amoxicillin hydrate and metronidazole
D08774  
Amoxicillin hydrate, clarithromycin and lansoprazole  <US>
Clopidogrel
 D07729  
Clopidogrel (USP/INN)
 D00769  
Clopidogrel bisulfate (USP); Clopidogrel sulfate (JP17); Clopidogrel sulfate tablets (JP17)  <JP/US>
 D10823  
Clopidogrel hydrochloride
 D10824  
Clopidogrel besilate
D01896  
Cilostazol (JP17/USP/INN)  <JP/US>
D10527  
Acetylsalicylic acid and lansoprazole  <JP>
D07077  
Ambrisentan (JAN/INN)  <JP/US>
Propranolol
 D08443  
Propranolol (INN)
 D00483  
Propranolol hydrochloride (JP17/USP)  <JP/US>
D01173  
Cilnidipine (JP17/INN)  <JP>
Terbinafine
 D02375  
Terbinafine (USAN/INN)
 D02219  
Terbinafine hydrochloride (JP17/USP)  <JP/US>
Doxepin
 D07875  
Doxepin (INN)
 D00814  
Doxepin hydrochloride (USP)  <US>
D02577  
Flibanserin (USAN/INN)  <US>
D04463  
Norgestrel and ethinylestradiol tablets (JP17)  <JP/US>
D00066  
Progesterone (JP17/USP/INN)  <JP/US>
Nelfinavir
 D08259  
Nelfinavir (INN)
 D00899  
Nelfinavir mesylate (USAN/INN); Nelfinavir mesilate (JAN)  <US>
D04112  
Etravirine (JAN/USAN/INN)  <JP/US>
Lapatinib
 D08108  
Lapatinib (INN)
 D04024  
Lapatinib ditosylate (USAN); Lapatinib tosilate hydrate (JAN)  <JP>
Tofacitinib
 D09970  
Tofacitinib (USAN)
 D09783  
Tofacitinib citrate (JAN/USAN)  <JP/US>
D01583  
Pirfenidone (JAN/USAN/INN)  <JP/US>
D11576  
Naproxen and esomeprazole magnesium  <US>
D00768  
Carisoprodol (JAN/USP/INN)  <US>
Esketamine
 D07283  
Esketamine (USAN/INN)
 D10627  
Esketamine hydrochloride (JAN/USAN)  <US>
D00700  
Mephobarbital (JAN/USP); Methylphenobarbital (INN)
Phenytoin
 D00512  
Phenytoin (JP17/USP/INN)  <JP/US>
 D02103  
Phenytoin sodium (USP); Phenytoin sodium for injection (JP17)  <JP/US>
D00375  
Mephenytoin (USP/INN)
Fosphenytoin
 D07993  
Fosphenytoin (INN)
 D02096  
Fosphenytoin sodium (USP)  <US>
 D07595  
Fosphenytoin sodium hydrate (JAN)  <JP>
D03844  
Phenytoin, phenobarbital and caffeine and sodium benzoate
D07583  
Phenytoin and phenobarbital  <JP>
D05928  
Stiripentol (JAN/USAN/INN)  <JP/US>
D07299  
Lacosamide (JAN/USAN/INN)  <JP/US>
D08879  
Brivaracetam (JAN/USAN/INN)  <US>
D10915  
Cannabidiol (USAN/INN)  <US>
D05768  
Rotigotine (JAN/USAN/INN)  <JP/US>
D00293  
Diazepam (JP17/USP/INN)  <JP/US>
D01253  
Clobazam (JAN/USAN/INN)  <JP/US>
D08283  
Nordazepam (INN)
Dexmedetomidine
 D00514  
Dexmedetomidine (USAN/INN)
 D01205  
Dexmedetomidine hydrochloride (JAN/USP)  <JP/US>
D10082  
Suvorexant (JAN/USAN)  <JP/US>
Imipramine
 D08070  
Imipramine (INN)
 D00815  
Imipramine hydrochloride (JP17/USP)  <JP/US>
 D08071  
Imipramine pamoate (USP)  <US>
Clomipramine
 D07727  
Clomipramine (INN)
 D00811  
Clomipramine hydrochloride (JP17/USP)  <JP/US>
Amitriptyline
 D07448  
Amitriptyline (INN)
 D00809  
Amitriptyline hydrochloride (JP17/USP)  <JP/US>
Sertraline
 D02360  
Sertraline (INN)
 D00825  
Sertraline hydrochloride (JAN/USP)  <JP/US>
Escitalopram
 D07913  
Escitalopram (INN)
 D02567  
Escitalopram oxalate (JAN/USP)  <JP/US>
D02561  
Moclobemide (USAN/INN)
Vilazodone
 D09698  
Vilazodone (USAN/INN)
 D09699  
Vilazodone hydrochloride (USAN)  <US>
Vortioxetine
 D10184  
Vortioxetine (USAN)
 D10185  
Vortioxetine hydrobromide (JAN/USAN)  <JP/US>
Methadone
 D08195  
Methadone (BAN)
 D02102  
Methadone hydrochloride (JAN/USP)  <JP/US>
Proguanil
 D08428  
Proguanil (INN)
 D02487  
Proguanil hydrochloride (JAN/USP)
D02472  
Atovaquone and proguanil hydrochloride  <JP/US>
Hydrocodone
 D08045  
Hydrocodone (INN)
 D03725  
Hydrocodone bitartrate (USP)  <US>
 D04461  
Hydrocodone polistirex (USAN)
 D08046  
Hydrocodone hydrochloride
Dorzolamide
 D07871  
Dorzolamide (INN)
 D00653  
Dorzolamide hydrochloride (JP17/USP)  <JP/US>
D08493  
Dorzolamide hydrochloride and timolol maleate  <JP/US>
Sarpogrelate
 D08508  
Sarpogrelate (INN)
 D01624  
Sarpogrelate hydrochloride (JP17)  <JP>
Fedratinib
 D10630  
Fedratinib (USAN/INN)
 D11296  
Fedratinib hydrochloride (USAN)  <US>
D10466  
Vonoprazan fumarate (JAN/USAN)  <JP>
D10513  
Clopidogrel sulfate and aspirin  <JP>
D10519  
Rabeprazole, amoxicillin and clarithromycin  <JP>
D10520  
Rabeprazole, amoxicillin and metronidazole  <JP>
D10525  
Valsartan and cilnidipine  <JP>
D10774  
Vonoprazan, amoxicillin and metronidazole  <JP>
D10775  
Vonoprazan, amoxicillin and clarithromycin  <JP>
D11586  
Carisoprodol and aspirin  <US>
D11587  
Carisoprodol, aspirin and codeine phosphate  <US>
D11616  
Aspirin and omeprazole  <US>
D11706  
Omeprazole and sodium bicarbonate  <US>
 » expand
Class
Metabolizing enzyme substrate
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