KEGG ORTHOLOGY: K10571

ORTHOLOGY: K10571

Entry

K10571                      KO

Symbol

DET1

Name

de-etiolated-1

Pathway

map04120

Ubiquitin mediated proteolysis

Brite

KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    K10571  DET1; de-etiolated-1
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K10571  DET1; de-etiolated-1
Ubiquitin system [BR:ko04121]
Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   Cul4 complex
    Target recognizing subunit (DCAF)
     K10571  DET1; de-etiolated-1

Genes

HSA:	55070(DET1)

PPS:	100967796(DET1)

GGO:	101134907(DET1)

PON:	100460452(DET1)

PPYG:

129014362(DET1)

NLE:	100584950(DET1)

HMH:	116481511(DET1)

SSYN:

129482103(DET1)

MCC:	697994(DET1)

MCF:	102125653(DET1)

MTHB:

126958910

MNI:	105488349(DET1)

CSAB:

103231132(DET1)

CATY:

105592425(DET1)

PANU:

101015258(DET1)

TGE:	112628646(DET1)

MLEU:

105544050(DET1)

RRO:	104661604(DET1)

RBB:	108535786(DET1)

TFN:	117070252(DET1)

PTEH:

111522859(DET1)

CANG:

105516225(DET1)

CJC:	100410207(DET1)

SBQ:	101046874(DET1)

CIMI:

108287608(DET1)

ANAN:

105707641(DET1)

CSYR:

103259527(DET1)

MMUR:

105884703(DET1)

LCAT:

123645159(DET1)

PCOQ:

105809836(DET1)

OGA:	100958803(DET1)

MMU:	76375(Det1)

MCAL:

110298358(Det1)

MPAH:

110324933(Det1)

RNO:	308775(Det1)

MCOC:

116102427(Det1)

ANU:	117698108(Det1)

MUN:	110552438(Det1)

CGE:	100770116(Det1)

MAUA:

101844579(Det1)

PROB:

127238130(Det1)

PLEU:

114699874(Det1)

MORG:

121447436(Det1)

MFOT:

126508715

AAMP:

119802872(Det1)

NGI:	103749922(Det1)

HGL:	101725685(Det1)

CPOC:

100732872(Det1)

CCAN:

109693798(Det1)

DORD:

105982263(Det1)

DSP:	122118612 122123956(Det1)

PLOP:

125343216 125368482(Det1)

NCAR:

124976893

MMMA:

107148443(Det1)

OCU:

100343868

OPI:	101516855(DET1)

TUP:	102481839(DET1)

GVR:	103585722(DET1)

CFA:	479036(DET1)

CLUD:

112653315(DET1)

VVP:	112921826(DET1)

VLG:	121489691(DET1)

NPO:	129510529(DET1)

AML:	100475401(DET1)

UMR:	103660170(DET1)

UAH:	113263675(DET1)

UAR:	123802404(DET1)

ELK:

111152610

LLV:

125105085

MPUF:

101692856(DET1)

MNP:	131999060(DET1)

MLK:	131835629(DET1)

NVS:	122893431(DET1)

ORO:	101381253(DET1)

EJU:	114223285(DET1)

ZCA:	113909936(DET1)

MLX:	118023035(DET1)

NSU:	110572285(DET1)

LWW:	102735460(DET1)

FCA:	101084794(DET1)

PYU:	121042417(DET1)

PCOO:

112856258(DET1)

PBG:	122468248(DET1)

PVIV:

125168676(DET1)

LRUF:

124517325

PTG:	102967194(DET1)

PPAD:

109273410(DET1)

PUC:

125910281

AJU:

106965857

HHV:	120220233(DET1)

BTA:	541005(DET1)

BOM:	102267209(DET1)

BIU:	109575589(DET1)

BBUB:

102403938(DET1)

BBIS:

105000729(DET1)

CHX:	102176645(DET1)

OAS:	101115993(DET1)

BTAX:

128066431(DET1)

ODA:	120875657(DET1)

CCAD:

122419607(DET1)

MBEZ:

129550259(DET1)

SSC:	100521834(DET1)

CFR:	102524503(DET1)

CBAI:

105075184(DET1)

CDK:	105085461(DET1)

VPC:	102528565(DET1)

BACU:

103010161(DET1)

BMUS:

118890196(DET1)

LVE:	103084354(DET1)

OOR:	101288964(DET1)

DLE:	111169337(DET1)

PCAD:

102993461(DET1)

PSIU:

116747986(DET1)

NASI:

112391553(DET1)

ECB:	100053984(DET1)

EPZ:	103554385(DET1)

EAI:	106832017(DET1)

MYB:	102250448(DET1)

MYD:	102760187(DET1)

MMYO:

118679208(DET1)

MLF:	102419513 102429983(DET1)

PKL:	118704310(DET1)

EFUS:

103301942(DET1)

MNA:	107527796(DET1)

DRO:	112306066(DET1)

SHON:

118991984(DET1)

AJM:	119049112(DET1)

PDIC:

114488562(DET1)

PHAS:

123809564(DET1)

MMF:	118640965(DET1)

PPAM:

129073897(DET1)

HAI:	109394767(DET1)

RFQ:	117018825(DET1)

PALE:

102881083(DET1)

PGIG:

120599313(DET1)

PVP:	105305198(DET1)

RAY:	107514178(DET1)

MJV:	108402155(DET1)

TOD:	119244302(DET1)

SARA:

101544199(DET1)

SETR:

126022369(DET1)

LAV:	100665900(DET1)

TMU:

101347726

ETF:	101648688(DET1)

DNM:	101447288(DET1)

MDO:	100013553(DET1)

GAS:	123236190(DET1)

SHR:	100925927(DET1)

AFZ:

127551376

PCW:	110193123(DET1)

TVP:	118830324(DET1) 118852697

OAA:	100087935(DET1)

GGA:	415497(DET1)

PCOC:

116225397(DET1)

MGP:	100549428(DET1)

CJO:	107318800(DET1)

TPAI:

128075415(DET1)

LMUT:

125698153(DET1)

NMEL:

110403651(DET1)

APLA:

101792893(DET1)

ACYG:

106036480(DET1)

CATA:

118252017(DET1)

AFUL:

116493734(DET1)

TGU:	100217762(DET1)

LSR:	110474196(DET1)

SCAN:

103816078(DET1)

PMOA:

120508895(DET1)

OTC:	121343358(DET1)

PRUF:

121354301(DET1)

GFR:	102035785(DET1)

FAB:	101807645(DET1)

OMA:	130257240(DET1)

PHI:	102099994(DET1)

PMAJ:

107209460(DET1)

CCAE:

111946044(DET1)

CCW:	104683932(DET1)

CBRC:

103621305(DET1)

ETL:	114058025(DET1)

ZAB:	102065198(DET1)

ZLE:	135452404(DET1)

ACHL:

103811474(DET1)

SVG:	106859235(DET1)

MMEA:

130573395(DET1)

HRT:	120758663(DET1)

FPG:	101911774(DET1)

FCH:	102058079(DET1)

CLV:	102090576(DET1)

EGZ:	104123604(DET1)

NNI:	104017081(DET1)

PCRI:

104038770(DET1)

PLET:

104628750(DET1)

EHS:	104506471(DET1)

PCAO:

104053624(DET1)

ACUN:

113484147(DET1)

TALA:

104359623(DET1)

PADL:

103926323(DET1)

AFOR:

103896675(DET1)

ACHC:

115341340(DET1)

HALD:

104323940(DET1)

HLE:	104834562(DET1)

AGEN:

126043640

GCL:

127020835

CCRI:

104166992(DET1)

CSTI:

104552997(DET1)

CMAC:

104475897(DET1)

MUI:	104534435(DET1)

BREG:

104643114(DET1)

FGA:	104083601(DET1)

GSTE:

104261439(DET1)

LDI:	104349142(DET1)

MNB:	103781171(DET1)

OHA:	104332079(DET1)

NNT:	104412602(DET1)

SHAB:

115612655(DET1)

DPUB:

104303358(DET1)

PGUU:

104467794(DET1)

ACAR:

104517925(DET1)

CPEA:

104394446(DET1)

AVIT:

104275776(DET1)

CVF:	104288437(DET1)

RTD:	128914709(DET1)

CUCA:

104059706(DET1)

TEO:	104378025(DET1)

BRHI:

104493208(DET1)

AAM:	106497609(DET1)

AROW:

112969850(DET1)

NPD:	112944792(DET1)

TGT:	104565520(DET1)

DNE:	112996030(DET1)

SCAM:

104148196(DET1)

ASN:	102385779(DET1)

AMJ:	102558619(DET1)

CPOO:

109309123(DET1)

GGN:	109288506(DET1)

PSS:	102460324(DET1)

CMY:	102938907(DET1)

CCAY:

125643641(DET1)

DCC:	119862699(DET1)

CPIC:

101938565(DET1)

TST:	117884251(DET1)

CABI:

116840123(DET1)

MRV:	120372974(DET1)

ACS:	100565065(det1)

ASAO:

132762305(DET1)

PVT:	110072965(DET1)

SUND:

121935568(DET1)

PBI:	103066523(DET1)

PMUR:

107293681(DET1)

CTIG:

120315119(DET1)

TSR:	106538922(DET1)

PGUT:

117669899(DET1)

APRI:

131184563(DET1)

PTEX:

113442053(DET1)

NSS:	113421475(DET1)

VKO:	123027652(DET1)

PMUA:

114584099(DET1)

PRAF:

128401422(DET1)

ZVI:	118092899(DET1)

HCG:	128334868(DET1)

GJA:	107124470(DET1)

STOW:

125424723(DET1)

EMC:	129345187(DET1)

XLA:	444462(det1.L)

XTR:	100379904(det1)

NPR:	108796892(DET1)

RTEM:

120931189(DET1)

BBUF:

120985943(DET1)

BGAR:

122927538(DET1)

MUO:	115459887(DET1)

GSH:	117348524(DET1)

DRE:	324089(det1)

SRX:	107707445 107714022

SANH:

107654110 107701843

SGH:	107581827 107583160

CCAR:

109064717 109084462

CAUA:

113043139 113066771 113080855

CGIB:

127946699 128014569

PTET:

122330950(det1)

LROH:

127156247(det1)

OMC:	131534655(det1)

PPRM:

120460193(det1)

RKG:	130085191(det1)

MAMB:

125247213(det1)

CIDE:

127507490

MASI:

127437834

TROS:

130551907(det1)

TDW:	130414274(det1)

MANU:

129433441(det1)

IPU:

108268416

IFU:	128611806(det1)

PHYP:

113546667(det1)

SMEO:

124385579(det1)

TFD:	113652304(det1)

TVC:	132855782(det1)

TRN:	134318757(det1)

AMEX:

103022743(det1)

CMAO:

118806540(det1)

EEE:	113590013(det1)

CHAR:

105892135(det1)

TRU:	101067971(det1)

TFS:	130536418(det1)

TNG:	GSTEN00006167G001

LCO:	104938581(det1)

NCC:	104948151(det1)

TBEN:

117491200(det1)

CGOB:

115010230(det1)

PGEO:

117447513(det1)

GACU:

117539629(det1)

EMAC:

134875322(det1)

ELY:	117261651(det1)

EFO:	125887896(det1)

PLEP:

121950244(det1)

SLUC:

116057710(det1)

ECRA:

117948889(det1)

ESP:	116694356(det1)

PFLV:

114560841(det1)

GAT:	120809636(det1)

PPUG:

119196664(det1)

AFB:	129108214(det1)

CLUM:

117732785(det1)

PSWI:

130195935(det1)

MSAM:

119893190(det1)

SCHU:

122875110(det1)

CUD:	121515517(det1)

ALAT:

119025047(det1)

MZE:	101485949(det1)

ONL:	100691243(det1)

OAU:	116315845(det1)

OLA:	101164229(det1)

OML:	112152897(det1)

CSAI:

133444639(det1)

XMA:	102229047(det1)

XCO:	114151830(det1)

XHE:	116711180(det1)

PRET:

103481213(det1)

PFOR:

103138845(det1)

PLAI:

106949630(det1)

PMEI:

106923695(det1)

GAF:	122835713(det1)

PPRL:

129367272(det1)

CVG:	107092621(det1)

CTUL:

119787244(det1)

GMU:	124877943(det1)

NFU:	107388538(det1)

KMR:	108250079(det1)

ALIM:

106520230(det1)

NWH:	119416155(det1)

AOCE:

111585861(det1)

MCEP:

125015560(det1)

CSEM:

103379488(det1)

POV:	109640721(det1)

SSEN:

122776513(det1)

HHIP:

117763876(det1)

HSP:	118110254(det1)

PPLT:

128445097(det1)

SMAU:

118315666(det1)

LCF:

108901928

SDU:	111225220(det1)

SLAL:

111655721(det1)

XGL:	120793845(det1)

HCQ:	109530481(det1)

SSCV:

125970716

SBIA:

133502316(det1)

PEE:	133402629(det1)

PTAO:

133478187(det1)

BPEC:

110169640(det1)

MALB:

109962556(det1)

BSPL:

114857794(det1)

SJO:	128358795(det1)

SASA:

100380576(det1) 106560940

STRU:

115151839 115196927

OTW:	112218429(det1) 112252254

OMY:	110493855(det1) 110510928

OGO:	123991981 124038112

ONE:	115109282 115134395

OKI:	109867347 109889246

OKE:	118396600(det1) 118401364

SALP:

111952937 111962263

SNH:	120053419 120066174

CCLU:

121531767 121545217 121576744

ELS:	105018512(det1)

SFM:	108926560(det1)

PKI:	111859178(det1)

AANG:

118228153(det1)

LOC:	102693081(det1)

PSPA:

121294310 121299089

ARUT:

117427773 117964206

PSEX:

120541408(det1)

LCM:	102351915(DET1)

CMK:	103189909(det1)

RTP:	109927089(det1)

CPLA:

122540951(det1)

HOC:	132834260(det1)

LERI:

129712808(det1)

PMRN:

116954961(DET1)

LRJ:	133348950(DET1)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

ARUN:

AJC:

SKO:

DME:	Dmel_CG6093(abo)

DER:

6543207

DSE:

6612091

DSI:	Dsimw501_GD22208(Dsim_GD22208)

DYA:	Dyak_GE13132

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI18896

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

AOQ:

TDA:	119662400 119681167

MDE:	101889190 101890624 131800593

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AALI:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ008362

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:	114875944 114876083

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_202508

BANY:

MJU:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PNAP:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CFEL:

CCRN:

API:	100162415 100168010

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

HVI:

MQU:	129001993 129002639

PHU:	Phum_PHUM307480

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_306042

DMK:

DPZ:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:	135224410 135224962

HAZT:

EAF:

LSM:

TCF:

PPOI:

ISC:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

CSCU:

PTEP:

ABRU:

UDV:

LPOL:

PMEO:

BMY:	BM_BM12912(Bm12912)

LOA:	LOAG_16674

HRO:	HELRODRAFT_64519

LGI:	LOTGIDRAFT_121100

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CANU:

CVN:	111128538 111128539

OED:

MYI:

PMAX:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

LLON:

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_50870

AQU:

105313297

ATH:	AT4G10180(DET1)

ALY:

9308567

CRB:

17881530

CSAT:

104707311 104721189 104737020

EUS:	EUTSA_v10028566mg

BRP:

103858553

BNA:	106423569 106436448

BOE:

RSZ:

THJ:

CPAP:

CIT:

CIC:	CICLE_v10015119mg

PVY:	116128876 116146562

MINC:

123228362

TCC:

18608416

GRA:

105779517

GHI:	107898887 107949219

GAB:

108470678

HSYR:

120129373 120188337 120200392

DZI:

111282820

EGR:

104444547

GMX:	100785677 100790158 100801685

GSJ:	114367013 114375976 114384023

PVU:	PHAVU_002G0354000

VRA:	106757024 106776581

VAR:

VUN:

VUM:

CCAJ:

APRC:

MTR:

TPRA:

CAM:

PSAT:

VVO:

ADU:

AIP:

AHF:	112749757 112801385

LANG:

109348581

PCIN:

129309199

QSA:	O6P43_022108

FVE:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:

MSYL:

PXB:

ZJU:

MNT:

CSAV:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

MEAN:

JCU:

HBR:

MESC:

POP:

PEU:

PALZ:

JRE:	109005020 109020263

CILL:

CAVE:

QLO:

TWL:

VVI:

VRI:

SLY:	778329(Det1)

SPEN:

SOT:

SSTN:

SDUL:

CANN:

LBB:

NTA:	107785321 107817062

NSY:

NTO:

NAU:

INI:

ITR:

SIND:

OEU:

EGT:

SSPL:

SMIL:

SHIS:

APAN:

HAN:

ECAD:

LSV:

CCAV:

DCR:

CSIN:

RVL:

AEW:

BVG:

SOE:

CQI:	110716013 110722146

ATRI:

MOF:

NNU:

MING:

TSS:	122639267 122647645

PSOM:

OSA:

OBR:

OGL:

BDI:

ATS:	109738707 109752128

TDC:	119268076 119276062

TAES:

123061186 123069905 123085700 123097641

TUA:	125528979 125530865

LPER:

127345893

LRD:

124667886

SBI:

8080887

ZMA:	100273813 100281541

SITA:

SVS:

PVIR:

PHAI:

PDA:

EGU:	105054632 105059434

MUS:

103990379

ZOF:	121988900 121997843 122001337 122005631

DCT:

PEQ:

AOF:

MSIN:

NCOL:

ATR:

SMO:	SELMODRAFT_104399(DET1-2) SELMODRAFT_167525(DET1-1)

PPP:	112274312 112288606 112296060

CSL:	COCSUDRAFT_48944

CVR:	CHLNCDRAFT_143175

OLU:	OSTLU_16748

OTA:	OT_ostta09g01840

BPG:	Bathy10g02750

GSL:	Gasu_45670

CCP:	CHC_T00003849001

MBR:	MONBRDRAFT_24110

DPP:	DICPUDRAFT_155299

DFA:

DFA_08723

» show all

Reference

PMID:17588513

Authors

Lee J, Zhou P.

Title

DCAFs, the missing link of the CUL4-DDB1 ubiquitin ligase.

Journal

Mol Cell 26:775-80 (2007)
DOI:10.1016/j.molcel.2007.06.001

Reference

PMID:14739464

Authors

Wertz IE, O'Rourke KM, Zhang Z, Dornan D, Arnott D, Deshaies RJ, Dixit VM.

Title

Human De-etiolated-1 regulates c-Jun by assembling a CUL4A ubiquitin ligase.

Journal

Science 303:1371-4 (2004)
DOI:10.1126/science.1093549

Sequence

[hsa:55070]

LinkDB

DBGET integrated database retrieval system