KEGG   PATHWAY: cvf04820
Entry
cvf04820                    Pathway                                
Name
Cytoskeleton in muscle cells - Charadrius vociferus (killdeer)
Class
Cellular Processes; Cell motility
Pathway map
cvf04820  Cytoskeleton in muscle cells
cvf04820

Organism
Charadrius vociferus (killdeer) [GN:cvf]
Gene
104281539  ITGB8; integrin beta-8 [KO:K06591]
104281582  [KO:K06238]
104281583  [KO:K06238]
104281649  SSPN; LOW QUALITY PROTEIN: sarcospan [KO:K22194]
104281681  FBLN1; fibulin-1 [KO:K17307]
104281696  CSRP2; cysteine and glycine-rich protein 2 isoform X1 [KO:K09377]
104281719  CAPZA3; LOW QUALITY PROTEIN: F-actin-capping protein subunit alpha-3 [KO:K10364]
104281816  FHL3; four and a half LIM domains protein 3 [KO:K24414]
104281846  ITGB4; integrin beta-4 [KO:K06525]
104281849  ATP1A1; sodium/potassium-transporting ATPase subunit alpha-1 [KO:K01539] [EC:7.2.2.13]
104281918  LAMA1; LOW QUALITY PROTEIN: laminin subunit alpha-1 [KO:K05637]
104281939  MYH10; myosin-10 isoform X1 [KO:K10352]
104282023  [KO:K12315]
104282115  LAMA2; laminin subunit alpha-2 [KO:K05637]
104282221  MYL2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351]
104282378  DAAM2; disheveled-associated activator of morphogenesis 2 [KO:K04512]
104282417  MYL3; myosin light chain 3 [KO:K12749]
104282421  OBSCN; obscurin [KO:K17531] [EC:2.7.11.1]
104282429  COL9A1; collagen alpha-1(IX) chain [KO:K08131]
104282434  MYOM2; myomesin-2 [KO:K24495]
104282511  LMNB2; lamin-B2 [KO:K07611]
104282533  TMOD1; tropomodulin-1 [KO:K10370]
104282767  [KO:K23342]
104282905  SNTB1; beta-1-syntrophin [KO:K24064]
104282977  DTNA; dystrobrevin alpha isoform X1 [KO:K26998]
104283151  LMOD1; leiomodin-1 [KO:K22030]
104283164  TNNT2; LOW QUALITY PROTEIN: troponin T, cardiac muscle [KO:K12045]
104283165  TNNI1; troponin I, slow skeletal muscle [KO:K10371]
104283166  CSRP1; cysteine and glycine-rich protein 1 isoform X1 [KO:K09377]
104283181  MYBPH; myosin-binding protein H [KO:K24494]
104283362  SYNE3; LOW QUALITY PROTEIN: nesprin-3 [KO:K21761]
104283397  NRAP; nebulin-related-anchoring protein [KO:K24421]
104283525  FHL1; four and a half LIM domains protein 1 isoform X1 [KO:K14365]
104283579  DIAPH2; protein diaphanous homolog 2 [KO:K05741]
104283660  MYH9; myosin-9 [KO:K10352]
104283672  SUN2; SUN domain-containing protein 2 [KO:K19347]
104283972  TRIM63; E3 ubiquitin-protein ligase TRIM63 [KO:K10655] [EC:2.3.2.27]
104283982  MYOM3; myomesin-3 [KO:K24495]
104284287  DCN; decorin [KO:K04660]
104284354  [KO:K17751]
104284615  PDLIM5; PDZ and LIM domain protein 5 [KO:K19867]
104284704  FHL2; four and a half LIM domains protein 2 [KO:K14380]
104284826  FMNL3; formin-like protein 3 [KO:K23957]
104285068  MYL7; myosin regulatory light chain 2, atrial isoform [KO:K12754]
104285096  THBS1; thrombospondin-1 [KO:K16857]
104285133  DMD; dystrophin [KO:K10366]
104285135  SDC4; syndecan-4 [KO:K16338]
104285149  [KO:K17751]
104285166  LMOD3; leiomodin-3 [KO:K22030]
104285236  LMOD2; leiomodin-2 [KO:K22030]
104285295  FMNL1; formin-like protein 1 [KO:K23957]
104285374  ITGB3; integrin beta-3 [KO:K06493]
104285387  MYL4; myosin light chain 4 [KO:K12750]
104285561  FMNL2; LOW QUALITY PROTEIN: formin-like protein 2 [KO:K23957]
104285566  NEB; LOW QUALITY PROTEIN: nebulin [KO:K18267]
104285576  [KO:K24220]
104285591  SYNE1; nesprin-1 [KO:K19326]
104285663  DES; desmin [KO:K07610]
104285682  [KO:K05745]
104285787  THBS4; thrombospondin-4 [KO:K04659]
104286206  COL11A1; LOW QUALITY PROTEIN: collagen alpha-1(XI) chain [KO:K19721]
104286308  COL24A1; collagen alpha-1(XXIV) chain [KO:K19721]
104286399  SGCZ; zeta-sarcoglycan [KO:K27062]
104286429  SGCB; beta-sarcoglycan [KO:K12566]
104286530  [KO:K06271]
104286671  [KO:K24220]
104286676  MYH13; myosin-13 [KO:K24220]
104286677  [KO:K24220]
104286725  SDC1; syndecan-1 [KO:K06257]
104286738  COL5A3; collagen alpha-3(V) chain [KO:K19721]
104286791  DSP; desmoplakin [KO:K10381]
104286928  TRIM55; tripartite motif-containing protein 55 [KO:K10654]
104286940  DAAM1; LOW QUALITY PROTEIN: disheveled-associated activator of morphogenesis 1 [KO:K04512]
104286974  TTN; LOW QUALITY PROTEIN: titin [KO:K12567] [EC:2.7.11.1]
104286976  ITGA4; LOW QUALITY PROTEIN: integrin alpha-4 [KO:K06483]
104287025  [KO:K10374]
104287061  TMOD2; tropomodulin-2 isoform X1 [KO:K10370]
104287062  TMOD3; tropomodulin-3 [KO:K10370]
104287149  SUN1; SUN domain-containing protein 1 [KO:K19347]
104287247  ACTN2; alpha-actinin-2 isoform X1 [KO:K21073]
104287257  NID1; nidogen-1 [KO:K06826]
104287301  DSG2; LOW QUALITY PROTEIN: desmoglein-2 [KO:K07597]
104287303  DSC1; desmocollin-1 [KO:K07601]
104287318  SPTBN1; spectrin beta chain, non-erythrocytic 1 isoform X1 [KO:K06115]
104287432  FBN1; fibrillin-1 [KO:K06825]
104287449  [KO:K07611]
104287537  CSRP3; cysteine and glycine-rich protein 3 [KO:K09377]
104287607  MYL9; myosin regulatory light polypeptide 9 [KO:K12755]
104287709  MYH15; myosin-15 isoform X1 [KO:K24220]
104287837  MYH11; myosin-11 isoform X1 [KO:K10352]
104287907  MYOM1; myomesin-1 [KO:K24495]
104287954  TLN2; talin-2 isoform X1 [KO:K06271]
104288164  ACTC1; actin, alpha cardiac muscle 1 [KO:K12314]
104288289  PKP2; plakophilin-2 [KO:K12642]
104288300  CAPZA2; F-actin-capping protein subunit alpha-2 [KO:K10364]
104288327  VIM; vimentin [KO:K07606]
104288338  NEBL; nebulette [KO:K25865]
104288458  ITGB5; LOW QUALITY PROTEIN: integrin beta-5 [KO:K06588]
104288612  MYBPC1; LOW QUALITY PROTEIN: myosin-binding protein C, slow-type [KO:K12557]
104288722  MYL1; myosin light chain 1/3, skeletal muscle isoform isoform X1 [KO:K05738]
104288731  COL6A3; collagen alpha-3(VI) chain [KO:K06238]
104288739  FN1; fibronectin [KO:K05717]
104288828  ANKRD2; ankyrin repeat domain-containing protein 2 [KO:K21434]
104288970  COMP; cartilage oligomeric matrix protein [KO:K04659]
104288995  MYOZ2; myozenin-2 isoform X1 [KO:K26050]
104288996  SYNPO2; synaptopodin-2 isoform X1 [KO:K24066]
104289069  CAPN3; calpain-3 isoform X1 [KO:K08573] [EC:3.4.22.54]
104289122  SPTAN1; spectrin alpha chain, non-erythrocytic 1 isoform X1 [KO:K06114]
104289134  COL27A1; collagen alpha-1(XXVII) chain [KO:K19721]
104289205  TMOD4; tropomodulin-4 [KO:K10370]
104289265  ANK2; ankyrin-2 [KO:K09255]
104289486  CAPZA1; F-actin-capping protein subunit alpha-1 [KO:K10364]
104289523  AMPD1; AMP deaminase 1 [KO:K01490] [EC:3.5.4.6]
104289722  [KO:K28413]
104289752  PDLIM1; PDZ and LIM domain protein 1 isoform X1 [KO:K23353]
104289758  MYOZ1; myozenin-1 isoform X1 [KO:K26050]
104289790  ANKRD1; ankyrin repeat domain-containing protein 1 [KO:K21433]
104289828  VCL; vinculin [KO:K05700]
104289931  ITGA8; integrin alpha-8 [KO:K06584]
104290146  ACTB; actin, cytoplasmic 1 isoform X1 [KO:K05692]
104290215  COL4A5; collagen alpha-5(IV) chain [KO:K06237]
104290265  ATP1B4; LOW QUALITY PROTEIN: protein ATP1B4 [KO:K01540]
104290273  COL4A6; collagen alpha-6(IV) chain [KO:K06237]
104290396  [KO:K10388]
104290474  ENO1; alpha-enolase isoform X1 [KO:K01689] [EC:4.2.1.11]
104290547  AGRN; LOW QUALITY PROTEIN: agrin [KO:K06254]
104290590  FBN2; fibrillin-2 isoform X1 [KO:K23342]
104290596  LMNB1; lamin-B1 [KO:K07611]
104290685  ANK3; ankyrin-3 [KO:K09259]
104290742  TMEM43; transmembrane protein 43 [KO:K27488]
104290766  FBLN2; fibulin-2 [KO:K17307]
104290810  CAPZB; F-actin-capping protein subunit beta isoform X1 [KO:K10365]
104290948  COL5A2; collagen alpha-2(V) chain [KO:K19721]
104291018  ITGAV; integrin alpha-V [KO:K06487]
104291019  COL3A1; collagen alpha-1(III) chain [KO:K19720]
104291067  COL4A4; collagen alpha-4(IV) chain [KO:K06237]
104291079  COL4A3; collagen alpha-3(IV) chain [KO:K06237]
104291160  ATP1B3; sodium/potassium-transporting ATPase subunit beta-3 [KO:K01540]
104291262  XIRP1; xin actin-binding repeat-containing protein 1 [KO:K27381]
104291348  [KO:K04659]
104291362  LMNA; lamin [KO:K12641]
104291378  COL9A2; collagen alpha-2(IX) chain [KO:K08131]
104291388  SGCG; gamma-sarcoglycan [KO:K12564]
104291515  PDLIM4; PDZ and LIM domain protein 4 [KO:K23353]
104291631  [KO:K10056]
104291682  AMPD3; AMP deaminase 3 isoform X1 [KO:K01490] [EC:3.5.4.6]
104291828  MYOT; myotilin [KO:K19875]
104291844  ACTA1; actin, alpha skeletal muscle isoform X1 [KO:K10354]
104291913  SYNE2; LOW QUALITY PROTEIN: nesprin-2 [KO:K19346]
104291929  [KO:K06115]
104291934  TNNC1; troponin C, slow skeletal and cardiac muscles isoform X1 [KO:K05865]
104292070  COL6A2; collagen alpha-2(VI) chain [KO:K06238]
104292071  COL6A1; collagen alpha-1(VI) chain [KO:K06238]
104292131  THBS2; thrombospondin-2 [KO:K04659]
104292205  ITGA9; integrin alpha-9 [KO:K06585]
104292236  TPM3; tropomyosin alpha-3 chain isoform X1 [KO:K09290]
104292293  ATP1B1; sodium/potassium-transporting ATPase subunit beta-1 [KO:K01540]
104292386  PDLIM3; PDZ and LIM domain protein 3 isoform X1 [KO:K23353]
104292523  SDC2; syndecan-2 [KO:K16336]
104292621  TNNI2; troponin I, fast skeletal muscle [KO:K12043]
104292623  TNNT3; troponin T, fast skeletal muscle [KO:K12046]
104292671  ITGA11; integrin alpha-11 [KO:K06587]
104292677  MYH7B; myosin-7B [KO:K24220]
104292742  COL4A2; collagen alpha-2(IV) chain [KO:K06237]
104292743  COL4A1; collagen alpha-1(IV) chain [KO:K06237]
104292888  ZYX; zyxin [KO:K06273]
104292892  COL5A1; collagen alpha-1(V) chain [KO:K19721]
104292955  ENO2; gamma-enolase isoform X1 [KO:K01689] [EC:4.2.1.11]
104293124  MYOZ3; myozenin-3 [KO:K26050]
104293140  SGCD; delta-sarcoglycan [KO:K12563]
104293473  AMPD2; AMP deaminase 2 [KO:K01490] [EC:3.5.4.6]
104293518  SDC3; syndecan-3 [KO:K16337]
104293523  LDB3; LIM domain-binding protein 3 [KO:K19867]
104293756  PDLIM7; PDZ and LIM domain protein 7 isoform X1 [KO:K19867]
104293904  COL9A3; collagen alpha-3(IX) chain [KO:K08131]
104293965  TNNC2; troponin C, skeletal muscle [KO:K12042]
104294088  FMN2; formin-2 [KO:K02184]
104294349  NID2; nidogen-2 [KO:K06826]
104294378  MYPN; myopalladin [KO:K22028]
104294571  ITGA1; integrin alpha-1 [KO:K06480]
104294596  ITGA2; integrin alpha-2 [KO:K06481]
104294657  LBR; lamin-B receptor [KO:K19532] [EC:1.3.1.70]
104294708  [KO:K24220]
104294716  [KO:K24220]
104294718  DAG1; dystroglycan [KO:K06265]
104294880  ITGA6; integrin alpha-6 [KO:K06485]
104294930  ITGB6; integrin beta-6 [KO:K06589]
104295369  ITGB1; integrin beta-1 [KO:K05719]
104295419  TPM4; tropomyosin alpha-4 chain isoform X1 [KO:K10375]
104295581  COL1A2; collagen alpha-2(I) chain [KO:K06236]
104295598  SGCE; epsilon-sarcoglycan [KO:K27061]
104295654  [KO:K24220]
104295656  [KO:K24220]
104295657  [KO:K24220]
104295850  MYBPC3; myosin-binding protein C, cardiac-type [KO:K12568]
104295913  SPTBN5; spectrin beta chain, non-erythrocytic 5 [KO:K06115]
104296025  [KO:K06236]
Reference
PMID:12142273
  Authors
Clark KA, McElhinny AS, Beckerle MC, Gregorio CC
  Title
Striated muscle cytoarchitecture: an intricate web of form and function.
  Journal
Annu Rev Cell Dev Biol 18:637-706 (2002)
DOI:10.1146/annurev.cellbio.18.012502.105840
Reference
PMID:31407867
  Authors
Mukund K, Subramaniam S
  Title
Skeletal muscle: A review of molecular structure and function, in health and disease.
  Journal
Wiley Interdiscip Rev Syst Biol Med 12:e1462 (2020)
DOI:10.1002/wsbm.1462
Reference
PMID:24481844
  Authors
Stroud MJ, Banerjee I, Veevers J, Chen J
  Title
Linker of nucleoskeleton and cytoskeleton complex proteins in cardiac structure, function, and disease.
  Journal
Circ Res 114:538-48 (2014)
DOI:10.1161/CIRCRESAHA.114.301236
Reference
PMID:28640448
  Authors
Henderson CA, Gomez CG, Novak SM, Mi-Mi L, Gregorio CC
  Title
Overview of the Muscle Cytoskeleton.
  Journal
Compr Physiol 7:891-944 (2017)
DOI:10.1002/cphy.c160033
Reference
PMID:32265741
  Authors
Csapo R, Gumpenberger M, Wessner B
  Title
Skeletal Muscle Extracellular Matrix - What Do We Know About Its Composition, Regulation, and Physiological Roles? A Narrative Review.
  Journal
Front Physiol 11:253 (2020)
DOI:10.3389/fphys.2020.00253
Reference
PMID:27114860
  Authors
Pinch M, Guth R, Samanta MP, Chaidez A, Unguez GA
  Title
The myogenic electric organ of Sternopygus macrurus: a non-contractile tissue with a skeletal muscle transcriptome.
  Journal
PeerJ 4:e1828 (2016)
DOI:10.7717/peerj.1828
Reference
PMID:23860255
  Authors
Sequeira V, Nijenkamp LL, Regan JA, van der Velden J
  Title
The physiological role of cardiac cytoskeleton and its alterations in heart failure.
  Journal
Biochim Biophys Acta 1838:700-22 (2014)
DOI:10.1016/j.bbamem.2013.07.011
Reference
PMID:36960155
  Authors
Zhang B, Powers JD, McCulloch AD, Chi NC
  Title
Nuclear mechanosignaling in striated muscle diseases.
  Journal
Front Physiol 14:1126111 (2023)
DOI:10.3389/fphys.2023.1126111
Reference
PMID:21464301
  Authors
Al-Amoudi A, Castano-Diez D, Devos DP, Russell RB, Johnson GT, Frangakis AS
  Title
The three-dimensional molecular structure of the desmosomal plaque.
  Journal
Proc Natl Acad Sci U S A 108:6480-5 (2011)
DOI:10.1073/pnas.1019469108
Reference
PMID:33067392
  Authors
Sikora M, Ermel UH, Seybold A, Kunz M, Calloni G, Reitz J, Vabulas RM, Hummer G, Frangakis AS
  Title
Desmosome architecture derived from molecular dynamics simulations and cryo-electron tomography.
  Journal
Proc Natl Acad Sci U S A 117:27132-27140 (2020)
DOI:10.1073/pnas.2004563117
Reference
PMID:26910421
  Authors
Xu XP, Kim E, Swift M, Smith JW, Volkmann N, Hanein D
  Title
Three-Dimensional Structures of Full-Length, Membrane-Embedded Human alpha(IIb)beta(3) Integrin Complexes.
  Journal
Biophys J 110:798-809 (2016)
DOI:10.1016/j.bpj.2016.01.016
Reference
PMID:22945352
  Authors
Wang W, Shi Z, Jiao S, Chen C, Wang H, Liu G, Wang Q, Zhao Y, Greene MI, Zhou Z
  Title
Structural insights into SUN-KASH complexes across the nuclear envelope.
  Journal
Cell Res 22:1440-52 (2012)
DOI:10.1038/cr.2012.126
Reference
PMID:23597672
  Authors
Sosa BA, Kutay U, Schwartz TU
  Title
Structural insights into LINC complexes.
  Journal
Curr Opin Struct Biol 23:285-91 (2013)
DOI:10.1016/j.sbi.2013.03.005
Reference
PMID:33058875
  Authors
Cruz VE, Esra Demircioglu F, Schwartz TU
  Title
Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes.
  Journal
J Mol Biol 432:6028-6041 (2020)
DOI:10.1016/j.jmb.2020.09.019
Reference
PMID:36523505
  Authors
Schuler SC, Liu Y, Dumontier S, Grandbois M, Le Moal E, Cornelison D, Bentzinger CF
  Title
Extracellular matrix: Brick and mortar in the skeletal muscle stem cell niche.
  Journal
Front Cell Dev Biol 10:1056523 (2022)
DOI:10.3389/fcell.2022.1056523
Reference
PMID:30425656
  Authors
Brull A, Morales Rodriguez B, Bonne G, Muchir A, Bertrand AT
  Title
The Pathogenesis and Therapies of Striated Muscle Laminopathies.
  Journal
Front Physiol 9:1533 (2018)
DOI:10.3389/fphys.2018.01533
Reference
PMID:36552829
  Authors
Storey EC, Fuller HR
  Title
Genotype-Phenotype Correlations in Human Diseases Caused by Mutations of LINC Complex-Associated Genes: A Systematic Review and Meta-Summary.
  Journal
Cells 11:cells11244065 (2022)
DOI:10.3390/cells11244065
Related
pathway
cvf04512  ECM-receptor interaction
cvf04814  Motor proteins
KO pathway
ko04820   

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