KEGG   PATHWAY: prob04714
Entry
prob04714                   Pathway                                
Name
Thermogenesis - Phodopus roborovskii (desert hamster)
Description
Thermogenesis is essential for warm-blooded animals, ensuring normal cellular and physiological function under conditions of environmental challenge. Thermogenesis in brown and beige adipose tissue is mainly controlled by norepinephrine, which is released from sympathetic nervous system in response to cold or dietary stimuli. The mitochondrial uncoupling protein 1 (UCP1) is responsible for the process whereby chemical energy is converted into heat in these adipocytes. Activation of these adipocytes leads to an increase in calorie consumption and is expected to improve overweight conditions, providing a potential strategy for treating obesity and its related metabolic disorders.
Class
Organismal Systems; Environmental adaptation
Pathway map
prob04714  Thermogenesis
prob04714

Other DBs
GO: 1990845
Organism
Phodopus roborovskii (desert hamster) [GN:prob]
Gene
127220380  Adrb3; beta-3 adrenergic receptor [KO:K04143]
127222868  neuroendocrine secretory protein 55-like [KO:K04632]
127222787  Gnas; guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas isoform X1 [KO:K04632]
127233912  Adcy1; adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
127220711  Adcy2; adenylate cyclase type 2 isoform X1 [KO:K08042] [EC:4.6.1.1]
127220046  Adcy3; adenylate cyclase type 3 [KO:K08043] [EC:4.6.1.1]
127230359  Adcy4; adenylate cyclase type 4 [KO:K08044] [EC:4.6.1.1]
127227112  Adcy5; adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
127226028  Adcy6; adenylate cyclase type 6 isoform X1 [KO:K08046] [EC:4.6.1.1]
127229980  Adcy7; adenylate cyclase type 7 isoform X1 [KO:K08047] [EC:4.6.1.1]
127235293  Adcy8; adenylate cyclase type 8 isoform X1 [KO:K08048] [EC:4.6.1.1]
127219617  Adcy9; adenylate cyclase type 9 isoform X1 [KO:K08049] [EC:4.6.1.1]
127223525  Adcy10; adenylate cyclase type 10 [KO:K11265] [EC:4.6.1.1]
127229872  Prkaca; cAMP-dependent protein kinase catalytic subunit alpha isoform X1 [KO:K04345] [EC:2.7.11.11]
127229917  Prkacb; cAMP-dependent protein kinase catalytic subunit beta isoform X1 [KO:K04345] [EC:2.7.11.11]
127226375  Creb1; cyclic AMP-responsive element-binding protein 1 isoform X1 [KO:K05870]
127222230  Creb3l1; cyclic AMP-responsive element-binding protein 3-like protein 1 isoform X1 [KO:K09048]
127216557  Creb3l3; cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1 [KO:K09048]
127217490  cyclic AMP-responsive element-binding protein 3-like protein 2 [KO:K09048]
127224594  Creb3; cyclic AMP-responsive element-binding protein 3 [KO:K09048]
127232866  Creb3l4; cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X1 [KO:K09048]
127214253  Creb3l2; cyclic AMP-responsive element-binding protein 3-like protein 2 isoform X1 [KO:K09048]
127235522  Creb5; LOW QUALITY PROTEIN: cyclic AMP-responsive element-binding protein 5 [KO:K09047]
127213457  Prdm16; histone-lysine N-methyltransferase PRDM16 [KO:K22410] [EC:2.1.1.367]
127235071  Znf516; zinc finger protein 516 isoform X1 [KO:K22411]
127213383  Kdm1a; lysine-specific histone demethylase 1A isoform X1 [KO:K11450] [EC:1.14.99.66]
127229860  Ucp1; mitochondrial brown fat uncoupling protein 1 [KO:K08769]
127235108  Kdm3b; lysine-specific demethylase 3B isoform X1 [KO:K15601] [EC:1.14.11.65]
127235779  Kdm3a; lysine-specific demethylase 3A [KO:K15601] [EC:1.14.11.65]
127231289  Smarca4; transcription activator BRG1 isoform X1 [KO:K11647] [EC:5.6.2.-]
127233393  Smarca2; probable global transcription activator SNF2L2 isoform X1 [KO:K11647] [EC:5.6.2.-]
127224114  Smarcb1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 isoform X1 [KO:K11648]
127215627  Smarcc2; SWI/SNF complex subunit SMARCC2 isoform X1 [KO:K11649]
127236117  Smarcc1; SWI/SNF complex subunit SMARCC1 isoform X1 [KO:K11649]
127235799  Smarcd3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 isoform X1 [KO:K11650]
127218274  Smarcd2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 isoform X1 [KO:K11650]
127226070  Smarcd1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 [KO:K11650]
127215686  Smarce1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 isoform X1 [KO:K11651]
127234394  uncharacterized protein LOC127234394 [KO:K05692]
127234395  uncharacterized protein LOC127234395 [KO:K05692]
127234396  uncharacterized protein LOC127234396 [KO:K05692]
127217780  uncharacterized protein LOC127217780 [KO:K05692]
127237213  Actb; actin, cytoplasmic 1 isoform X1 [KO:K05692]
127237366  uncharacterized protein LOC127237366 [KO:K05692]
127220241  Actg1; actin, cytoplasmic 2 [KO:K05692]
127214100  uncharacterized protein LOC127214100 [KO:K05692]
127214101  uncharacterized protein LOC127214101 [KO:K05692]
127223332  Actl6a; actin-like protein 6A isoform X1 [KO:K11340]
127237211  Actl6b; actin-like protein 6B [KO:K11652]
127225505  Arid1a; AT-rich interactive domain-containing protein 1A isoform X1 [KO:K11653]
127237740  Arid1b; AT-rich interactive domain-containing protein 1B isoform X1 [KO:K11653]
127230947  Dpf3; zinc finger protein DPF3 isoform X1 [KO:K22198]
127238719  Dpf1; zinc finger protein neuro-d4 isoform X1 [KO:K22198]
127236259  Pparg; peroxisome proliferator-activated receptor gamma isoform X1 [KO:K08530]
127215051  Map3k5; mitogen-activated protein kinase kinase kinase 5 isoform X1 [KO:K04426] [EC:2.7.11.25]
127219179  Map2k3; dual specificity mitogen-activated protein kinase kinase 3 [KO:K04432] [EC:2.7.12.2]
127224210  Mapk13; mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
127224217  Mapk14; mitogen-activated protein kinase 14 isoform X1 [KO:K04441] [EC:2.7.11.24]
127225455  mitogen-activated protein kinase 13-like [KO:K04441] [EC:2.7.11.24]
127225941  Mapk12; mitogen-activated protein kinase 12 isoform X1 [KO:K04441] [EC:2.7.11.24]
127225942  Mapk11; mitogen-activated protein kinase 11 [KO:K04441] [EC:2.7.11.24]
127213598  Ppargc1a; peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1 [KO:K07202]
127222404  Atf2; cyclic AMP-dependent transcription factor ATF-2 isoform X1 [KO:K04450]
127216568  Sirt6; NAD-dependent protein deacylase sirtuin-6 isoform X1 [KO:K11416] [EC:2.3.1.286]
127213944  Fgf21; fibroblast growth factor 21 [KO:K22429]
127238159  Plin1; perilipin-1 [KO:K08768]
127238774  hormone-sensitive lipase [KO:K07188] [EC:3.1.1.79]
127228542  Pnpla2; patatin-like phospholipase domain-containing protein 2 [KO:K16816] [EC:3.1.1.3]
127235989  Mgll; monoglyceride lipase isoform X1 [KO:K01054] [EC:3.1.1.23]
127224997  Prkaa2; 5'-AMP-activated protein kinase catalytic subunit alpha-2 [KO:K07198] [EC:2.7.11.31]
127220610  Prkaa1; 5'-AMP-activated protein kinase catalytic subunit alpha-1 [KO:K07198] [EC:2.7.11.31]
127216002  Prkab1; 5'-AMP-activated protein kinase subunit beta-1 [KO:K07199]
127233006  Prkab2; 5'-AMP-activated protein kinase subunit beta-2 isoform X1 [KO:K07199]
127235796  Prkag2; 5'-AMP-activated protein kinase subunit gamma-2 isoform X1 [KO:K07200]
127226041  Prkag1; 5'-AMP-activated protein kinase subunit gamma-1 [KO:K07200]
127226445  Prkag3; 5'-AMP-activated protein kinase subunit gamma-3 [KO:K07200]
127222478  Gcg; pro-glucagon isoform X1 [KO:K05259]
127225306  bone morphogenetic protein 8B [KO:K16622]
127225314  bone morphogenetic protein 8A [KO:K16622]
127224475  Cnr1; cannabinoid receptor 1 [KO:K04277]
127213212  Nppa; natriuretic peptides A [KO:K12334]
127213244  Nppb; natriuretic peptides B [KO:K12335]
127233107  Npr1; atrial natriuretic peptide receptor 1 [KO:K12323] [EC:4.6.1.2]
127233462  Prkg1; cGMP-dependent protein kinase 1 isoform X1 [KO:K07376] [EC:2.7.11.12]
127232334  Prkg2; cGMP-dependent protein kinase 2 [KO:K19477] [EC:2.7.11.12]
127232288  Klb; beta-klotho [KO:K22404]
127220342  Fgfr1; fibroblast growth factor receptor 1 isoform X1 [KO:K04362] [EC:2.7.10.1]
127215727  Frs2; fibroblast growth factor receptor substrate 2 [KO:K12461]
127219174  Grb2; growth factor receptor-bound protein 2 [KO:K04364]
127217013  Sos1; son of sevenless homolog 1 [KO:K03099]
127230645  Sos2; son of sevenless homolog 2 isoform X1 [KO:K03099]
127228530  Hras; GTPase HRas [KO:K02833]
127213087  Kras; GTPase KRas isoform X1 [KO:K07827]
127233129  Nras; GTPase NRas [KO:K07828]
127216119  Rps6ka3; ribosomal protein S6 kinase alpha-3 isoform X1 [KO:K04373] [EC:2.7.11.1]
127237637  Rps6ka2; ribosomal protein S6 kinase alpha-2 isoform X1 [KO:K04373] [EC:2.7.11.1]
127213392  Rps6ka1; ribosomal protein S6 kinase alpha-1 isoform X1 [KO:K04373] [EC:2.7.11.1]
127226602  Rps6ka6; ribosomal protein S6 kinase alpha-6 [KO:K04373] [EC:2.7.11.1]
127222678  Tsc1; hamartin isoform X1 [KO:K07206]
127219556  Tsc2; tuberin isoform X1 [KO:K07207]
127235802  Rheb; GTP-binding protein Rheb [KO:K07208]
127220055  Rptor; regulatory-associated protein of mTOR [KO:K07204]
127213510  Mtor; serine/threonine-protein kinase mTOR [KO:K07203] [EC:2.7.11.1]
127219561  Mlst8; target of rapamycin complex subunit LST8 isoform X1 [KO:K08266]
127213931  Akt1s1; proline-rich AKT1 substrate 1 isoform X1 [KO:K16184]
127228636  Rps6kb2; ribosomal protein S6 kinase beta-2 [KO:K04688] [EC:2.7.11.1]
127224001  Rps6kb1; ribosomal protein S6 kinase beta-1 isoform X1 [KO:K04688] [EC:2.7.11.1]
127236638  40S ribosomal protein S6 [KO:K02991]
127224923  Rps6; 40S ribosomal protein S6 [KO:K02991]
127217133  Acsl4; long-chain-fatty-acid--CoA ligase 4 isoform X1 [KO:K01897] [EC:6.2.1.3]
127219281  Acsl6; long-chain-fatty-acid--CoA ligase 6 [KO:K01897] [EC:6.2.1.3]
127226487  Acsl3; fatty acid CoA ligase Acsl3 [KO:K01897] [EC:6.2.1.3]
127220533  Acsl1; long-chain-fatty-acid--CoA ligase 1 isoform X1 [KO:K01897] [EC:6.2.1.3]
127233565  Acsl5; long-chain-fatty-acid--CoA ligase 5 isoform X1 [KO:K01897] [EC:6.2.1.3]
30213863  BOP69_gp13; NADH dehydrogenase subunit 1 [KO:K03878] [EC:7.1.1.2]
30213866  BOP69_gp12; NADH dehydrogenase subunit 2 [KO:K03879] [EC:7.1.1.2]
30213875  BOP69_gp06; NADH dehydrogenase subunit 3 [KO:K03880] [EC:7.1.1.2]
30213853  BOP69_gp04; NADH dehydrogenase subunit 4 [KO:K03881] [EC:7.1.1.2]
30213876  BOP69_gp05; NADH dehydrogenase subunit 4L [KO:K03882] [EC:7.1.1.2]
30213879  BOP69_gp03; NADH dehydrogenase subunit 5 [KO:K03883] [EC:7.1.1.2]
30213855  BOP69_gp02; NADH dehydrogenase subunit 6 [KO:K03884] [EC:7.1.1.2]
127226362  Ndufs1; NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial [KO:K03934] [EC:7.1.1.2]
127223568  Ndufs2; NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial [KO:K03935] [EC:7.1.1.2]
127222286  Ndufs3; NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial [KO:K03936] [EC:7.1.1.2]
127225317  Ndufs5; NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 [KO:K03938]
127231389  NADH dehydrogenase [ubiquinone] iron-sulfur protein 5-like [KO:K03938]
127233027  NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 [KO:K03938]
127220858  Ndufs6; NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial [KO:K03939]
127216631  Ndufs7; NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial [KO:K03940] [EC:7.1.1.2]
127228614  Ndufs8; NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial [KO:K03941] [EC:7.1.1.2]
127228621  Ndufv1; NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial [KO:K03942] [EC:7.1.1.2]
127226765  Ndufv2; NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial [KO:K03943] [EC:7.1.1.2]
127224173  Ndufv3; NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial [KO:K03944]
127235179  Ndufa2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 [KO:K03946]
127225561  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 [KO:K03947]
127238962  Ndufa3; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 [KO:K03947]
127215662  Ndufa4l2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 [KO:K03948]
127227199  cytochrome c oxidase subunit NDUFA4 [KO:K03948]
127215318  Ndufa4; cytochrome c oxidase subunit NDUFA4 [KO:K03948]
127215361  Ndufa5; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 [KO:K03949]
127225860  Ndufa6; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 [KO:K03950]
127217788  Ndufa7; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 [KO:K03951]
127222829  Ndufa8; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 [KO:K03952]
127212845  Ndufa9; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial [KO:K03953]
127218502  LOW QUALITY PROTEIN: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial-like [KO:K03954]
127226704  Ndufa10; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial [KO:K03954]
127228294  Ndufab1; acyl carrier protein, mitochondrial [KO:K03955]
127216779  Ndufa11; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 [KO:K03956]
127237896  Ndufa12; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 [KO:K11352]
127217171  Ndufa13; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 [KO:K11353]
127214232  Ndufb2; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial [KO:K03958]
127226334  Ndufb3; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 [KO:K03959]
127213479  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4-like [KO:K03960]
127227152  Ndufb4; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 [KO:K03960]
127227382  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4-like [KO:K03960]
127223336  Ndufb5; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial [KO:K03961]
127224505  Ndufb6; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 isoform X1 [KO:K03962]
127229861  Ndufb7; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 [KO:K03963]
127233334  Ndufb8; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial [KO:K03964]
127235381  Ndufb9; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 [KO:K03965]
127219546  Ndufb10; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 [KO:K03966]
127218277  Ndufb11; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial [KO:K11351]
127230881  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial-like [KO:K11351]
127237386  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial-like [KO:K11351]
127216294  Ndufc1; NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial [KO:K03967]
127227923  Ndufc2; NADH dehydrogenase [ubiquinone] 1 subunit C2 [KO:K03968]
127221614  Ndufaf1; complex I intermediate-associated protein 30, mitochondrial [KO:K18159]
127221041  Ndufaf2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 [KO:K18160]
127236413  Ndufaf3; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 [KO:K09008]
127232496  Ndufaf4; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 [KO:K18161]
127221375  Ndufaf5; arginine-hydroxylase NDUFAF5, mitochondrial [KO:K18162] [EC:2.1.1.-]
127232251  Ndufaf6; NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 [KO:K18163]
127217032  Ndufaf7; protein arginine methyltransferase NDUFAF7, mitochondrial [KO:K18164]
127221566  Ndufaf8; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8 [KO:K24726]
127220879  Sdha; succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial isoform X1 [KO:K00234] [EC:1.3.5.1]
127234957  LOW QUALITY PROTEIN: succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial-like [KO:K00235] [EC:1.3.5.1]
127213191  Sdhb; succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial [KO:K00235] [EC:1.3.5.1]
127214858  succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial [KO:K00235] [EC:1.3.5.1]
127223562  Sdhc; succinate dehydrogenase cytochrome b560 subunit, mitochondrial [KO:K00236]
127222110  succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial-like [KO:K00237]
127231714  Sdhd; succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial [KO:K00237]
127229373  cytochrome b-c1 complex subunit Rieske, mitochondrial [KO:K00411] [EC:7.1.1.8]
127234176  LOW QUALITY PROTEIN: cytochrome b-c1 complex subunit Rieske, mitochondrial-like [KO:K00411] [EC:7.1.1.8]
30213880  BOP69_gp01; cytochrome b [KO:K00412]
127225607  cytochrome c1, heme protein, mitochondrial [KO:K00413]
127236238  cytochrome b-c1 complex subunit 1, mitochondrial [KO:K00414]
127228268  cytochrome b-c1 complex subunit 2, mitochondrial [KO:K00415]
127225195  cytochrome b-c1 complex subunit 6, mitochondrial [KO:K00416]
127235340  cytochrome b-c1 complex subunit 7 [KO:K00417]
127232158  cytochrome b-c1 complex subunit 7-like [KO:K00417]
127219303  cytochrome b-c1 complex subunit 8 [KO:K00418]
30213871  BOP69_gp11; cytochrome c oxidase subunit I [KO:K02256] [EC:7.1.1.9]
30213873  BOP69_gp10; cytochrome c oxidase subunit II [KO:K02261]
30213850  BOP69_gp07; cytochrome c oxidase subunit III [KO:K02262]
127228584  cytochrome c oxidase subunit 4 isoform 2, mitochondrial [KO:K02263]
127234699  cytochrome c oxidase subunit 4 isoform 1, mitochondrial [KO:K02263]
127231812  cytochrome c oxidase subunit 5A, mitochondrial [KO:K02264]
127236762  cytochrome c oxidase subunit 5B, mitochondrial [KO:K02265]
127220855  cytochrome c oxidase subunit 5B, mitochondrial-like [KO:K02265]
127215993  cytochrome c oxidase subunit 6A1, mitochondrial [KO:K02266]
127227703  cytochrome c oxidase subunit 6A2, mitochondrial [KO:K02266]
127238390  cytochrome c oxidase subunit 6B2 isoform X1 [KO:K02267]
127238700  cytochrome c oxidase subunit 6B1 [KO:K02267]
127235327  cytochrome c oxidase subunit 6C-2 [KO:K02268]
127212991  cytochrome c oxidase subunit 7A2, mitochondrial [KO:K02270]
127238724  cytochrome c oxidase subunit 7A1, mitochondrial [KO:K02270]
127214896  cytochrome c oxidase subunit 7A-related protein, mitochondrial [KO:K02270]
127233672  cytochrome c oxidase subunit 7A-related protein, mitochondrial-like [KO:K02270]
127217663  cytochrome c oxidase subunit 7B, mitochondrial [KO:K02271]
127219135  protoheme IX farnesyltransferase, mitochondrial [KO:K02257] [EC:2.5.1.141]
127230373  cytochrome c oxidase assembly protein COX11, mitochondrial [KO:K02258]
127233502  cytochrome c oxidase assembly protein COX15 homolog [KO:K02259] [EC:1.17.99.9]
127227173  cytochrome c oxidase copper chaperone [KO:K02260]
127232117  cytochrome c oxidase assembly protein COX18, mitochondrial isoform X1 [KO:K17797]
127237260  cytochrome c oxidase assembly protein COX19 [KO:K18183]
127223673  cytochrome c oxidase assembly protein COX20, mitochondrial [KO:K18184]
127216622  cytochrome c oxidase assembly factor 3 homolog, mitochondrial [KO:K18175]
127227974  cytochrome c oxidase assembly factor 4 homolog, mitochondrial [KO:K18177]
127236763  cytochrome c oxidase assembly factor 5 [KO:K18178]
127234416  cytochrome c oxidase assembly factor 6 homolog [KO:K18179]
127225137  cytochrome c oxidase assembly factor 7 [KO:K18180]
127235073  Atp5f1a; ATP synthase subunit alpha, mitochondrial [KO:K02132]
127215643  Atp5f1b; ATP synthase subunit beta, mitochondrial [KO:K02133] [EC:7.1.2.2]
127229828  Atp5f1c; ATP synthase subunit gamma, mitochondrial [KO:K02136]
127226968  ATP synthase subunit gamma, mitochondrial [KO:K02136]
127216638  Atp5f1d; ATP synthase subunit delta, mitochondrial [KO:K02134]
127227528  Atp5po; ATP synthase subunit O, mitochondrial [KO:K02137]
30213849  BOP69_gp08; ATP synthase F0 subunit 6 [KO:K02126]
127233069  Atp5pb; ATP synthase F(0) complex subunit B1, mitochondrial isoform X1 [KO:K02127]
127221396  LOW QUALITY PROTEIN: ATP synthase F(0) complex subunit B1, mitochondrial-like [KO:K02127]
127222152  ATP synthase F(0) complex subunit C2, mitochondrial-like [KO:K02128]
127215909  ATP synthase F(0) complex subunit C2, mitochondrial-like [KO:K02128]
127222403  Atp5mc3; ATP synthase F(0) complex subunit C3, mitochondrial [KO:K02128]
127217469  ATP synthase F(0) complex subunit C2, mitochondrial [KO:K02128]
127224096  ATP synthase F(0) complex subunit C2, mitochondrial [KO:K02128]
127230764  ATP synthase F(0) complex subunit C2, mitochondrial-like [KO:K02128]
127225202  ATP synthase F(0) complex subunit C2, mitochondrial [KO:K02128]
127225599  ATP synthase F(0) complex subunit C2, mitochondrial-like [KO:K02128]
127220028  ATP synthase F(0) complex subunit C2, mitochondrial-like [KO:K02128]
127226169  Atp5mc2; ATP synthase F(0) complex subunit C2, mitochondrial [KO:K02128]
127238618  Atp5mc1; ATP synthase F(0) complex subunit C1, mitochondrial [KO:K02128]
127220598  ATP synthase F(0) complex subunit C1, mitochondrial [KO:K02128]
127214556  ATP synthase F(0) complex subunit C2, mitochondrial [KO:K02128]
127214557  ATP synthase F(0) complex subunit C2, mitochondrial [KO:K02128]
127234711  ATP synthase subunit d, mitochondrial-like [KO:K02138]
127219094  Atp5pd; ATP synthase subunit d, mitochondrial isoform X1 [KO:K02138]
127234686  ATP synthase subunit f, mitochondrial-like [KO:K02130]
127217707  ATP synthase subunit f, mitochondrial-like [KO:K02130]
127214223  ATP synthase subunit f, mitochondrial [KO:K02130]
127221132  ATP synthase subunit f, mitochondrial-like [KO:K02130]
127227454  Atp5pf; ATP synthase-coupling factor 6, mitochondrial [KO:K02131]
30213874  BOP69_gp09; ATP synthase F0 subunit 8 [KO:K02125]
127231626  Atp5mg; ATP synthase subunit g, mitochondrial [KO:K02140]
127225124  Cpt2; carnitine O-palmitoyltransferase 2, mitochondrial [KO:K08766] [EC:2.3.1.21]
127236402  Slc25a20; mitochondrial carnitine/acylcarnitine carrier protein [KO:K15109]
127231141  Slc25a29; mitochondrial basic amino acids transporter [KO:K15109]
127228604  Cpt1a; carnitine O-palmitoyltransferase 1, liver isoform [KO:K08765] [EC:2.3.1.21]
127225959  Cpt1b; carnitine O-palmitoyltransferase 1, muscle isoform [KO:K19523] [EC:2.3.1.21]
127213870  Cpt1c; carnitine O-palmitoyltransferase 1, brain isoform [KO:K19524] [EC:2.3.1.21]
Compound
C00002  ATP
C00004  NADH
C00008  ADP
C00010  CoA
C00024  Acetyl-CoA
C00040  Acyl-CoA
C00080  H+
C00116  Glycerol
C00162  Fatty acid
C00165  Diacylglycerol
C00318  L-Carnitine
C00422  Triacylglycerol
C00547  L-Noradrenaline
C00575  3',5'-Cyclic AMP
C00745  Nicotine
C00942  3',5'-Cyclic GMP
C00951  Estradiol-17beta
C01352  FADH2
C01885  1-Acylglycerol
C02301  O-Acylcarnitine
C02465  Triiodothyronine
C11695  Anandamide
C13856  2-Arachidonoylglycerol
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Nat Commun 6:7052 (2015)
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Related
pathway
prob00020  Citrate cycle (TCA cycle)
prob00190  Oxidative phosphorylation
prob04010  MAPK signaling pathway
prob04022  cGMP-PKG signaling pathway
prob04024  cAMP signaling pathway
prob04150  mTOR signaling pathway
prob04923  Regulation of lipolysis in adipocytes
KO pathway
ko04714   
LinkDB

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